Guide to the Human Genome
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Search of human proteins with 37655167

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]
         (432 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]          891   0.0  
gi|37655169 ring finger protein 135 isoform 2 [Homo sapiens]          357   9e-99
gi|15208660 tripartite motif protein 21 [Homo sapiens]                 93   4e-19
gi|217035095 tripartite motif-containing 62 [Homo sapiens]             91   2e-18
gi|38679905 tripartite motif-containing 65 [Homo sapiens]              91   2e-18
gi|68160937 tripartite motif-containing 25 [Homo sapiens]              91   3e-18
gi|21630277 tripartite motif-containing 11 [Homo sapiens]              85   1e-16
gi|56605981 tripartite motif-containing 72 [Homo sapiens]              82   7e-16
gi|22749269 ring finger protein 129 [Homo sapiens]                     78   1e-14
gi|157743261 tripartite motif-containing 75 [Homo sapiens]             77   2e-14
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]    76   5e-14
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]     76   5e-14
gi|31542779 tripartite motif family-like 1 [Homo sapiens]              75   2e-13
gi|210147600 tripartite motif-containing 64 [Homo sapiens]             74   3e-13
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-...    74   3e-13
gi|37622899 ring finger protein 137 [Homo sapiens]                     73   4e-13
gi|89886468 fibronectin type III and SPRY domain containing 1-li...    71   2e-12
gi|223718222 fibronectin type III and SPRY domain containing 1-l...    71   2e-12
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]       70   3e-12
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]       70   3e-12
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...    70   3e-12
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]    69   6e-12
gi|239755486 PREDICTED: tripartite motif-containing protein 64C-...    62   8e-10
gi|239755484 PREDICTED: tripartite motif-containing protein 64C-...    62   8e-10
gi|239750044 PREDICTED: tripartite motif-containing protein 64C-...    62   8e-10
gi|239750042 PREDICTED: tripartite motif-containing protein 64C-...    62   8e-10
gi|239744355 PREDICTED: tripartite motif-containing protein 64C-...    62   8e-10
gi|239744353 PREDICTED: tripartite motif-containing protein 64C-...    62   8e-10
gi|46409324 SPRY domain containing 4 [Homo sapiens]                    62   8e-10
gi|148596968 tripartite motif-containing 8 [Homo sapiens]              62   1e-09

>gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]
          Length = 432

 Score =  891 bits (2302), Expect = 0.0
 Identities = 432/432 (100%), Positives = 432/432 (100%)

Query: 1   MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP 60
           MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP
Sbjct: 1   MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP 60

Query: 61  TCRQGAAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAARPRRRP 120
           TCRQGAAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAARPRRRP
Sbjct: 61  TCRQGAAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAARPRRRP 120

Query: 121 ELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGKAFSSGVDL 180
           ELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGKAFSSGVDL
Sbjct: 121 ELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGKAFSSGVDL 180

Query: 181 SMASPKLVTSDTAAGKIRDILHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPL 240
           SMASPKLVTSDTAAGKIRDILHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPL
Sbjct: 181 SMASPKLVTSDTAAGKIRDILHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPL 240

Query: 241 PDQSHPALRRASRFAQWAIHPTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTS 300
           PDQSHPALRRASRFAQWAIHPTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTS
Sbjct: 241 PDQSHPALRRASRFAQWAIHPTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTS 300

Query: 301 QVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSRDQVLGRTMDSCCVEWKGTSQLSAW 360
           QVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSRDQVLGRTMDSCCVEWKGTSQLSAW
Sbjct: 301 QVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSRDQVLGRTMDSCCVEWKGTSQLSAW 360

Query: 361 HMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAFWLYGLH 420
           HMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAFWLYGLH
Sbjct: 361 HMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAFWLYGLH 420

Query: 421 PGNYLIIKQVKV 432
           PGNYLIIKQVKV
Sbjct: 421 PGNYLIIKQVKV 432


>gi|37655169 ring finger protein 135 isoform 2 [Homo sapiens]
          Length = 210

 Score =  357 bits (917), Expect = 9e-99
 Identities = 172/172 (100%), Positives = 172/172 (100%)

Query: 1   MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP 60
           MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP
Sbjct: 1   MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP 60

Query: 61  TCRQGAAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAARPRRRP 120
           TCRQGAAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAARPRRRP
Sbjct: 61  TCRQGAAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAARPRRRP 120

Query: 121 ELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGK 172
           ELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGK
Sbjct: 121 ELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGK 172


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 116/466 (24%), Positives = 185/466 (39%), Gaps = 77/466 (16%)

Query: 6   LGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQG 65
           + SA  + +  +++ C IC      P ++ CGHSFC+ C+  +     +    CP CRQ 
Sbjct: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGS---VCPVCRQR 57

Query: 66  AAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGS----------SSLSSAAAR 115
              + +LR N  L ++ +  +  ++E + G+    C   G            +L    A+
Sbjct: 58  FLLK-NLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQ 116

Query: 116 PRRRPELQRVAVEKSITEVA-------------QELTELVEHLVDIVRS----------- 151
            R+  +   V +E++  E               QEL E +E  + I R+           
Sbjct: 117 SRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKS 176

Query: 152 --------------LQNQRPLSESGPDN--ELSILGKAFSSGVDLSMASPKLVTSDTAAG 195
                          + QR L E   D   +L ILG+  +     S A  +L+ S+    
Sbjct: 177 RIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELI-SELDRR 235

Query: 196 KIRDILHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSH-PALRRASRF 254
                L  L+E+   L+ S +W            L+    +S  L    H P L++  R 
Sbjct: 236 CHSSALELLQEVIIVLERSESWN-----------LKDLDITSPELRSVCHVPGLKKMLRT 284

Query: 255 AQWAIHPTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERF-STSQVLCSQALSSGKH 313
              A+H T +  + +  L +S+D R V +    Q    + ERF S   VL +Q   SGKH
Sbjct: 285 C--AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKH 342

Query: 314 YWEVDTRNCSHWAVGVASWEMSR-DQVLGRTMDSCCVEWKGTSQLSAWHMVKETVLGSDR 372
           YWEVD      W +GV    + R    L  +       W    Q        +T L    
Sbjct: 343 YWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQV 402

Query: 373 PGV-VGIWLNLEEGKLAFYSVDNQEKLLY---ECTISASSPLYPAF 414
           P   VGI+L+ E G ++FY++ +   L+Y   EC    + PL P F
Sbjct: 403 PPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAF--TGPLRPFF 446


>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 108/439 (24%), Positives = 180/439 (41%), Gaps = 62/439 (14%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALW------GARDARRWACPTCRQGAAQQ 69
           +D+L C IC  +   P +L C H FCR C+   W      GARD     CP CR+  A +
Sbjct: 6   KDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARD-----CPECRRTFA-E 59

Query: 70  PHLRKNTLLQDLADKY-----------RRAAREIQAGSDPAHCPCPGSSSLSSAAARPRR 118
           P L  +  L ++ ++Y           RRAAR  QA            + L      P  
Sbjct: 60  PALAPSLKLANIVERYSSFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPAL 119

Query: 119 RPELQRVAVEKSITEVAQELTELVEHLVDIVRS-------LQNQRPLSESGPDNELSILG 171
             + Q   ++ +  E+ +EL + ++ L D  R        L+ Q   ++S   +  + +G
Sbjct: 120 HEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIG 179

Query: 172 KAFSSGVDLSMASPKL----VTSDTA-------------AGKIRDILHDLEEIQEKLQES 214
           +AF     L     K     + +DTA             + ++R +    + +QE+L E+
Sbjct: 180 EAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAET 239

Query: 215 -----VTWKEAPEAQMQGELLEAP-SSSSCPLPDQSHPALRRASRFAQWAIHP-----TF 263
                +    +   +++G++ E   +    P    + P      +     IHP     T 
Sbjct: 240 DRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTL 299

Query: 264 NLKSLSCSLEVSKDSRTVTVSH-RPQPYRWSCERFSTS-QVLCSQALSSGKHYWEVDTRN 321
           +  +    L +S D   V   +  PQP + S +RF     VL S+A SSG HYWEV    
Sbjct: 300 DPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAE 359

Query: 322 CSHWAVGVASWEMSR--DQVLGRTMDSCCVEWKGTSQLSAWHMVKETVLGSDRPGVVGIW 379
            + W +G+A    SR     +  +    C+     +Q SA       +   D+   VG++
Sbjct: 360 KTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVF 419

Query: 380 LNLEEGKLAFYSVDNQEKL 398
           L+ ++G L FY+ D+   L
Sbjct: 420 LDYDQGLLIFYNADDMSWL 438


>gi|38679905 tripartite motif-containing 65 [Homo sapiens]
          Length = 517

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 125/496 (25%), Positives = 186/496 (37%), Gaps = 102/496 (20%)

Query: 14  LAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLR 73
           L E+ L C IC GL   P TLPCGH+FC  C+   W   D    ACP CR+       LR
Sbjct: 5   LLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWW---DRCGKACPECREPFPDGAELR 61

Query: 74  KNTLLQDLADKYRRAAREIQAGSDP-------AHCP-----------CPGSSSLSSAAAR 115
           +N  L  + +   RA      G DP       A CP             G    S    R
Sbjct: 62  RNVALSGVLEVV-RAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCTVR 120

Query: 116 PRRRPE--------LQRVAVEKSITEVA-QELTELVEHLVDIVR---SLQNQRPLSESGP 163
             R  E        L+R A  ++  EV  Q+ T+    L+++ +    +QN   +  S  
Sbjct: 121 ECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWV 180

Query: 164 DNELSILGKAFSSGVDLSMASPKLVTSDTAAG--------------------KIRDILHD 203
             + S L +A       ++ S ++  +   A                     +IR++L  
Sbjct: 181 SGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQ 240

Query: 204 LEEIQEKLQES--------------VTWKEAPE--------AQMQGELLEAPSSSSCPL- 240
           ++E Q  LQES              + W E  +        +++ G LLE  S    P  
Sbjct: 241 VDE-QTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAK 299

Query: 241 -----------PDQSHPALRRASRFAQWAIHPTFNLKSLSCSLEVSKDSRTVTVSH-RPQ 288
                      P    P+     R   W  +       +S +       +   V H R  
Sbjct: 300 PVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQS 359

Query: 289 PYRWSCERFSTSQVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSRDQV------LGR 342
                   F   QV C+Q+  +G HYWEV   + S   +GV+  ++ R ++      +GR
Sbjct: 360 RGPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHS-VTLGVSYPQLPRCRLGPHTDNIGR 418

Query: 343 TMDS--CCVEWKGTSQLSAWHMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLY 400
              S   CV+      L AWH  +   L      ++G+ L+L  G L FYS++ Q + LY
Sbjct: 419 GPCSWGLCVQ---EDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPLY 475

Query: 401 ECTISASSPLYPAFWL 416
                 + PL P FWL
Sbjct: 476 TFHALFNQPLTPVFWL 491


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score = 90.5 bits (223), Expect = 3e-18
 Identities = 52/140 (37%), Positives = 78/140 (55%), Gaps = 5/140 (3%)

Query: 282 TVSHRPQPYRWSCERFS-TSQVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSR---D 337
           +V+  PQ YR   +RF+  SQVL       G HYWEV+ +  +   VG+    M+R   +
Sbjct: 480 SVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPE 539

Query: 338 QVLGRTMDSCCVEWKGTSQLSAWHMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEK 397
             LGR   S CVEW  T ++SAWH   E  L S +   VG+ LN + G + F++V ++  
Sbjct: 540 SRLGRNSASWCVEWFNT-KISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVH 598

Query: 398 LLYECTISASSPLYPAFWLY 417
           L+Y+  +  +  LYPAFW++
Sbjct: 599 LMYKFRVDFTEALYPAFWVF 618



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 5/96 (5%)

Query: 17  DDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKNT 76
           ++L C IC      P T PCGH+FC  CL   W  + +  + CP CR     +P L KNT
Sbjct: 9   EELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS-PYLCPQCRAVYQARPQLHKNT 67

Query: 77  LLQDLADKYRRA--AREIQAG--SDPAHCPCPGSSS 108
           +L ++ +++ +A  ARE  A   + PA    P  ++
Sbjct: 68  VLCNVVEQFLQADLAREPPADVWTPPARASAPSPNA 103


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 109/441 (24%), Positives = 170/441 (38%), Gaps = 51/441 (11%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
           +++  C IC      P    CGH+FCR C+   WG  +   +ACP CR+  + Q +LR N
Sbjct: 11  QEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEG-PYACPECRE-LSPQRNLRPN 68

Query: 76  TLLQDLADKYRR--AAREIQAGSDPAH-----CPCPGSSSLSSAAARPRRRPELQRVAVE 128
             L  +A+  RR      +  G  PAH       C     L  AA          RV   
Sbjct: 69  RPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRV--- 125

Query: 129 KSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGKAFSSGVDLSMASPKLV 188
           + + + A++L   +E  ++ +R  Q Q  L      +E  +L +        ++      
Sbjct: 126 RPLQDAAEDLKAKLEKSLEHLRK-QMQDALLFQAQADETCVLWQKMVESQRQNVLGEFER 184

Query: 189 TSDTAAGKIRDILHDLEEIQEKLQESVTWKEAPEAQMQGELLE--APSSSSCPLP----- 241
                A + + +L  LEE + ++   +    A   Q    L E  A     C LP     
Sbjct: 185 LRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGLL 244

Query: 242 DQSHPALRR-------------------------ASRFAQWAIHPTFNLKSLSCSLEVSK 276
                ALRR                              ++    T +  + +  L +S+
Sbjct: 245 QDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPELILSE 304

Query: 277 DSRTVTVSHRPQPYRWSCERFSTSQ-VLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMS 335
           D R+V      Q    S ERF     VL  +  +SG+HYWEV+  + + WA+GV    ++
Sbjct: 305 DRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVN 364

Query: 336 RDQVLGRTMDSCCVEWKGTSQLSAWHMVKETVLG--SDRPGVVGIWLNLEEGKLAFYSVD 393
           R +   +   S    +     L +++   E  L    D P  VGI+L+ E G L+FYS  
Sbjct: 365 RKE---KGELSAGNGFWILVFLGSYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSAT 421

Query: 394 NQEKLLYECTISASSPLYPAF 414
           +   L     I  S  L P F
Sbjct: 422 DGSLLFIFPEIPFSGTLRPLF 442


>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
          Length = 477

 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 124/463 (26%), Positives = 186/463 (40%), Gaps = 67/463 (14%)

Query: 8   SAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWA-CPTCR--- 63
           SA P  L   +L C +C  L D P T  CGHSFCR CL  + G   A     CP C+   
Sbjct: 2   SAAP-GLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPT 60

Query: 64  ---------------QGAAQQPHLRKNTLLQDLA-----DKYRRAAREIQAGSDPAHCPC 103
                          +G AQ P       L  L+     D+          GS   H   
Sbjct: 61  RPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLL 120

Query: 104 PGSSSLSSAAAR-PRRRPELQRVAV--EKSITEVAQELTELVEHLVDIVRSLQNQ----- 155
           P + + +    + P+++ +LQ   +  EKS+  +  +L E+ E +     ++  Q     
Sbjct: 121 PAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMR 180

Query: 156 --RPLSESGPDNELS-ILGKAFSSGVDLSMASPKLVTSDTAAGKIRDILHDLEEIQEKLQ 212
                 E   D E   + G+A   GV L     +L + ++   ++R +   LEE+ +K Q
Sbjct: 181 VFLAALEGSLDCEAERVRGEA---GVALRR---ELGSLNSYLEQLRQMEKVLEEVADKPQ 234

Query: 213 ESVTWKEA-PEAQMQGELLEAPSSSSCPLPDQSHPALRRASRFAQW-----AIHP----- 261
                K     +++Q  L E+P  +     D   P +    +F  W     A+ P     
Sbjct: 235 TEFLMKYCLVTSRLQKILAESPPPARL---DIQLPIISDDFKFQVWRKMFRALMPALEEL 291

Query: 262 TFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCER--FSTSQVLCSQALSSGKHYWEVDT 319
           TF+  S   SL VS   R V  S +  P      R       V+  Q LS G+HYWEVD 
Sbjct: 292 TFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDV 351

Query: 320 RNCSHWAVGVASWEMSRDQVLGRTMDSCCVEWKGTSQ---LSAWHMVKE-TVLGSD--RP 373
            +   WA+GV + E  R   L   + S  +   G  +   L A    KE   L S   RP
Sbjct: 352 GDKPRWALGVIAAEAPRRGRL-HAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRP 410

Query: 374 GVVGIWLNLEEGKLAFYSVDNQEKL--LYECTISASSPLYPAF 414
             +G++L+  +G L+FY   + + L  L+        P+YP F
Sbjct: 411 TRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFF 453


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 113/471 (23%), Positives = 182/471 (38%), Gaps = 99/471 (21%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
           +++  C IC   L  P T+ CGH+FCR CL   W   D   + CP CR         R+N
Sbjct: 11  QEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDT-FPCPVCRF-CFPYKSFRRN 68

Query: 76  TLLQDLAD-----KYRRAAREIQ------------------------------AGSDPAH 100
             L++L +     + RR+ R+ Q                              +     H
Sbjct: 69  PQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFSTKHQKH 128

Query: 101 CPCPGSSSLS------SAAARPRRR--PELQRVAVEKSITEVAQELTELVEHLVDIVRS- 151
             CP   + S        +  P R     +++V + +    V  EL + VE+  + + S 
Sbjct: 129 YICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSV--ELKKKVEYKREEINSE 186

Query: 152 -------LQN-QRPLSESGPDNELSILGKAFSSGVDLSMASPKLVTSDTAAGKIRDILHD 203
                  LQN Q  +     D E++IL K   + V+LS               +  + H 
Sbjct: 187 FEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELS-------------DYVSTLKHL 233

Query: 204 LEEIQEKLQES--VTWKEAPEAQMQGELLEAPSSSSCPLPDQSH---PALRRASRFAQ-W 257
           L E++ K  +S      +A     + + L+ P   S  L        P      R  + +
Sbjct: 234 LREVEGKSVQSNLELLTQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKPF 293

Query: 258 AIHPTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTSQ-VLCSQALSSGKHYWE 316
            +    +L +    L VS+D + V    + +   +   RF     VL SQ  SSG+HYWE
Sbjct: 294 QVDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWE 353

Query: 317 VDTRNCSHWAVGVA------SWE-----MSRDQVLGRTMDSCCV-EWKGTSQLSAWHMVK 364
           V+  N   W +GV       +W+     +     +GR M S  V     T+QL       
Sbjct: 354 VEVGNKPKWILGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYVASGPKTTQL------- 406

Query: 365 ETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAFW 415
              L   +P  +GI+L+ E G L+FY++ N   +LY      +  ++P F+
Sbjct: 407 ---LPVVKPSKIGIFLDYELGDLSFYNM-NDRSILYTFNDCFTEAVWPYFY 453


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 96/449 (21%), Positives = 177/449 (39%), Gaps = 65/449 (14%)

Query: 21  CIICQGLLDWPATLPCGHSFCRHCLEALWGARDARR-WACPTCRQGAAQQPHLRKNTLLQ 79
           C IC   L  P T+ CGH+FCR C++  W   D +  + CP CR    Q+ H R NT L 
Sbjct: 16  CSICLDYLSDPVTIECGHNFCRSCIQQSW--LDLQELFPCPVCRH-QCQEGHFRSNTQLG 72

Query: 80  DLAD--------KYRRAAREIQAGSDPAHCP------------CPGSSSLSSAAARPRRR 119
            + +        K  +  +E     +  + P            CP  +          R 
Sbjct: 73  RMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDHQGHHVRP 132

Query: 120 PELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLS-ESGPDNELSILGKAFS--- 175
            E   +   K      Q L + +  L  ++ S Q+++PL      +N+   L   F    
Sbjct: 133 IEKAAIHYRKRFCSYIQPLKKQLADLQKLI-STQSKKPLELREMVENQRQELSSEFEHLN 191

Query: 176 -------SGVDLSMASPKLVTSDTAAGKIRDILHDLEEIQEKLQESVTWKEAPEAQMQGE 228
                    V   +A  +       +  I    +    ++ +L + V   E  E ++  +
Sbjct: 192 QFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSELSELELLSQ 251

Query: 229 L---LEAPSSSS------------CPLPDQSHPALRRASRFAQWAIHPTFNLKSLSCSLE 273
           +    E+ + SS            C  P Q + AL+R  +  ++ +    + ++   +L 
Sbjct: 252 IKIFYESENESSPSIFSIHLKRDGCSFPPQ-YSALQRIIK--KFKVEIILDPETAHPNLI 308

Query: 274 VSKDSRTVTVSHRPQPYRWSCERFSTSQVLCS-QALSSGKHYWEVDTRNCSHWAVGVASW 332
           VS+D + V  + R Q      +RF+   V+       SG+H+WE++  + S WA+G+   
Sbjct: 309 VSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSEWAIGICKD 368

Query: 333 EMSRDQVLGRTMDSCCVEWKGTSQLSAWH---MVKETVLGSDRPGVVGIWLNLEEGKLAF 389
            +        +    C  W+   Q   +H        +L   +   +GI+L+ E G+++F
Sbjct: 369 SLPTKARRPSSAQQEC--WRIELQDDGYHAPGAFPTPLLLEVKARAIGIFLDYEMGEISF 426

Query: 390 YSVDNQEKLLYECTI--SASSPLYPAFWL 416
           Y++  +  +   CT   + + PL P F++
Sbjct: 427 YNMAEKSHI---CTFTDTFTGPLRPYFYV 452


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 110/465 (23%), Positives = 180/465 (38%), Gaps = 61/465 (13%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALW----GARDARR----WACPTCRQGAA 67
           +++  C IC      P    CGH+FCR C++  W    G +  R+    + CP CR+ + 
Sbjct: 11  QEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSP 70

Query: 68  QQPHL--RKNTLLQDLADKYRRAARE--IQAGSDPAHCPCPGSSSLSSAAARPRRRPELQ 123
           Q+  L  R  T + ++A ++    ++   Q   +P    C    S      R  R   L 
Sbjct: 71  QRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLH 130

Query: 124 RVA-VEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESG--------PDNELSILGKAF 174
           RV   E+++     +L E +E+L + +    N +   E           +    I+ +  
Sbjct: 131 RVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFE 190

Query: 175 SSGVDLSMASPKLVTS-----DTAAGKIRDIL-------HDLEEIQEKLQESVTWKEAPE 222
              + L     +L+ +     +  A ++R+ +       H LE +  +L+E  T      
Sbjct: 191 KMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQM 250

Query: 223 AQMQGELLEAPSSSSCPLPDQSHPALRRASRFAQWAIH----------PTFNLKSLSCSL 272
            Q   E L   ++ S   P+ + P   R        I           P          L
Sbjct: 251 LQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLL 310

Query: 273 EVSKDSRTVTVSHRPQPYRWSCERFSTSQVLCSQ-ALSSGKHYWEV--DTRNCSHWAVGV 329
             S+  R +  S     +  S +RF        Q A SSG+HYWEV  +    + WA+GV
Sbjct: 311 YESRQRRYLGSSPEGSGF-CSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGV 369

Query: 330 ASWEMSRDQVLGRTMDSCCVE---W-----KGTSQLSAWHMVKETVLGSDRPGVVGIWLN 381
                 RD V  +     C E   W     KGT  LS +  +   +L  + P  +GI+L+
Sbjct: 370 C-----RDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVML-MEPPSHMGIFLD 423

Query: 382 LEEGKLAFYSVDNQEKLLYECTISASSPLYPAFWLYGLHPGNYLI 426
            E G+++FYSV +   L      +   PL P F L     G  +I
Sbjct: 424 FEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVI 468


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 110/465 (23%), Positives = 180/465 (38%), Gaps = 61/465 (13%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALW----GARDARR----WACPTCRQGAA 67
           +++  C IC      P    CGH+FCR C++  W    G +  R+    + CP CR+ + 
Sbjct: 11  QEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSP 70

Query: 68  QQPHL--RKNTLLQDLADKYRRAARE--IQAGSDPAHCPCPGSSSLSSAAARPRRRPELQ 123
           Q+  L  R  T + ++A ++    ++   Q   +P    C    S      R  R   L 
Sbjct: 71  QRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLH 130

Query: 124 RVA-VEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESG--------PDNELSILGKAF 174
           RV   E+++     +L E +E+L + +    N +   E           +    I+ +  
Sbjct: 131 RVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFE 190

Query: 175 SSGVDLSMASPKLVTS-----DTAAGKIRDIL-------HDLEEIQEKLQESVTWKEAPE 222
              + L     +L+ +     +  A ++R+ +       H LE +  +L+E  T      
Sbjct: 191 KMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQM 250

Query: 223 AQMQGELLEAPSSSSCPLPDQSHPALRRASRFAQWAIH----------PTFNLKSLSCSL 272
            Q   E L   ++ S   P+ + P   R        I           P          L
Sbjct: 251 LQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLL 310

Query: 273 EVSKDSRTVTVSHRPQPYRWSCERFSTSQVLCSQ-ALSSGKHYWEV--DTRNCSHWAVGV 329
             S+  R +  S     +  S +RF        Q A SSG+HYWEV  +    + WA+GV
Sbjct: 311 YESRQRRYLGSSPEGSGF-CSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGV 369

Query: 330 ASWEMSRDQVLGRTMDSCCVE---W-----KGTSQLSAWHMVKETVLGSDRPGVVGIWLN 381
                 RD V  +     C E   W     KGT  LS +  +   +L  + P  +GI+L+
Sbjct: 370 C-----RDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVML-MEPPSHMGIFLD 423

Query: 382 LEEGKLAFYSVDNQEKLLYECTISASSPLYPAFWLYGLHPGNYLI 426
            E G+++FYSV +   L      +   PL P F L     G  +I
Sbjct: 424 FEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVI 468


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 104/439 (23%), Positives = 169/439 (38%), Gaps = 75/439 (17%)

Query: 17  DDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKNT 76
           ++L C IC      P T  CGHSFC  CL   W   +    +CP C +   + PH + N 
Sbjct: 12  EELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPL-SCPECWR-TLEGPHFQSNE 69

Query: 77  LLQDLADKYRRAAREIQAGSDP-------------------------AHCPCPGSSSLSS 111
            L  LA   R+   ++    D                          A         LSS
Sbjct: 70  RLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQSHGANRVHLSS 129

Query: 112 AAARPRR-------------RPELQRVAV-EKSITEVAQELTELVEHLVDIVRSLQNQRP 157
            A    R             R E Q V   EK   ++ QE T+  + +V  V        
Sbjct: 130 EAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQVV--VSEYMKMHQ 187

Query: 158 LSESGPDNELSILGKAFSSGVDLSMASPKLVTSDTAAGKIRDILHDLEEIQEKLQESV-- 215
             +     +L +L +     +     +   +T      +IR +   + +I+   Q S   
Sbjct: 188 FLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQ-----QIRSLSKMIAQIESSSQSSAFE 242

Query: 216 TWKEAPEAQMQGE--LLEAPSSSSCPLPDQSHPALRRASRFAQWAIHPTFNLKSLSCSLE 273
           + +E   A  + E  LL+ P +++  L       ++   R  +++   T +  + +  L 
Sbjct: 243 SLEEVRGALERSEPLLLQCPEATTTELSLCRITGMKEMLR--KFSTEITLDPATANAYLV 300

Query: 274 VSKDSRTVTVSHRPQPYRWSCERFSTSQ-VLCSQALSSGKHYWEVDTRNCSHWAVGVASW 332
           +S+D ++V      Q    + ERF  S  VL +Q  +SG+HYWEV+  N + W VG+   
Sbjct: 301 LSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKD 360

Query: 333 EMSRD-----------QVLGRTMDSCCVEWKGTSQLSAWHMVKETVLGSDRPGVVGIWLN 381
            +SR             ++G  +      W  +S L   H V+E V        VG++L+
Sbjct: 361 SVSRKGNLPKPPGDLFSLIGLKIGDDYSLWV-SSPLKGQH-VREPVC------KVGVFLD 412

Query: 382 LEEGKLAFYSVDNQEKLLY 400
            E G +AFY+    E L+Y
Sbjct: 413 YESGHIAFYN-GTDESLIY 430


>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
          Length = 449

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 90/444 (20%), Positives = 166/444 (37%), Gaps = 54/444 (12%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
           +++L C IC      P T+ CGHSFCR CL  L          CP+CR+  +++P+   N
Sbjct: 10  QNELICCICVNYFIDPVTIDCGHSFCRPCL-CLCSEEGRAPMRCPSCRK-ISEKPNFNTN 67

Query: 76  TLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAAR-----PRRRPELQRVAVEKS 130
            +L+ L+   R+   +    SD        +  L   A +     P              
Sbjct: 68  VVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSP 127

Query: 131 ITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGKAFSSGVDLSMASPKLVT- 189
           I   A+E  E +   +D +  +  +         N L+   + F S  D      +++T 
Sbjct: 128 IGWAAEECREKLIKEMDYLWEINQETR-------NNLNQETRTFHSLKDYVSVRKRIITI 180

Query: 190 ---------SDTAAGKIRDILHDLEEIQEKLQESVT----------------WK--EAPE 222
                     +     ++ +  + EE+ ++LQ+S                  W+    P+
Sbjct: 181 QYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHVPD 240

Query: 223 AQMQGELLEAPSSSSCPLPDQSHPALRRASRFA---------QWAIHPTFNLKSLSCSLE 273
            ++  ++    + +      +  P     + +           + +    + + + C + 
Sbjct: 241 VELLQDVRNVSARTDLAQMQKPQPVNPELTSWCITGVLDMLNNFRVDSALSTEMIPCYIS 300

Query: 274 VSKDSRTVTVSHRPQPYRWSCERFSTSQVLCSQALSSGKHYWEVDTRNCSHWAVGVASWE 333
           +S+D R V             +   +  V  +QA +SGKHYWEVD    S+W +GV    
Sbjct: 301 LSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCQDS 360

Query: 334 MSRDQ--VLGRTMDSCCVEWKGTSQLSAWHMVKETVLGSDRP-GVVGIWLNLEEGKLAFY 390
            + D   V+        +  K ++  S        +    RP G VG++L+ + G ++F+
Sbjct: 361 RTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFF 420

Query: 391 SVDNQEKLLYECTISASSPLYPAF 414
            V     +      S SSPL P F
Sbjct: 421 DVSKGSLIYGFPPSSFSSPLRPFF 444


>gi|169202375 PREDICTED: tripartite motif-containing protein
           64B-like [Homo sapiens]
          Length = 449

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 95/444 (21%), Positives = 168/444 (37%), Gaps = 54/444 (12%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
           +++L C IC      P T+ CGHSFCR CL  L          CP+CR+  +++P+   N
Sbjct: 10  QNELICCICVNYFIDPVTIDCGHSFCRPCL-CLCSEEGRAPMRCPSCRK-TSEKPNFNTN 67

Query: 76  TLLQDLADKYRRAAREIQAGSD----------PAHCPCPGSSSLSSAAARPRRRPELQRV 125
            +L+ L+   R+   +    SD             C           +  P         
Sbjct: 68  LVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAH-SHS 126

Query: 126 AVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGKAFSSGVDLSMASP 185
            +  +  E  ++L + +++L +I +  +N     E+   + L          + +     
Sbjct: 127 PIGWAAEECREKLIKEMDYLWEINQETRNNLN-QETSTFHSLKDYVSVRKRIITIQYQKM 185

Query: 186 KLVTSDTAAGKIRDILHDLEEIQEKLQES---VTWKEAPEAQMQGELLEAPSSSSCPLPD 242
            +   +     ++ +  + EE+ ++LQ+S   +T        M  EL E     +C +PD
Sbjct: 186 PIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWE-----TCHMPD 240

Query: 243 ----QSHPALRRASRFAQ-------------WAIHPTFNL------------KSLSCSLE 273
               Q    +   +  AQ             W I    ++            + + C + 
Sbjct: 241 VVLLQDVRNVSARTDLAQMQKPQPVNPELTSWCITGVLDMLNNFRVDSALSTEMIPCYIS 300

Query: 274 VSKDSRTVTVSHRPQPYRWSCERFSTSQVLCSQALSSGKHYWEVDTRNCSHWAVGVASWE 333
           +S+D R V             +   +  V  +QA +SGKHYWEVD    S+W +GV    
Sbjct: 301 LSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCRDS 360

Query: 334 MSRDQ--VLGRTMDSCCVEWKGTSQLSAWHMVKETVLGSDRP-GVVGIWLNLEEGKLAFY 390
            + D   V+        +  K ++  S        +    RP G VG++L+ + G ++F+
Sbjct: 361 RTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFF 420

Query: 391 SVDNQEKLLYECTISASSPLYPAF 414
            V     +      S SSPL P F
Sbjct: 421 DVSKGSLIYGFPPSSFSSPLRPFF 444


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 90/385 (23%), Positives = 140/385 (36%), Gaps = 72/385 (18%)

Query: 17  DDLGCIICQGLLDWPATLPCGHSFCRHCLEALW---GARDARRWACPTCRQGAAQQPHLR 73
           +++ C IC   L  P ++ CGHSFC  CL  LW   G      + CP CR    Q  +LR
Sbjct: 12  EEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCR-APVQPRNLR 70

Query: 74  KNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSS----------SLSSAAARPRRRPELQ 123
            N  L ++ +K R        G     C   G             +  A ++        
Sbjct: 71  PNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAHS 130

Query: 124 RVAVEKSITEVAQELTELVEHL----------------------VDIVRSLQN------- 154
            V +E    E   EL E +EHL                      + +    Q+       
Sbjct: 131 VVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFEK 190

Query: 155 -QRPLSESGPDNE----------LSILGKAFSSGVDLSMASPKLVTSDTAAGKIRDILHD 203
            QR L +  P +            S+  +A  +   L +   +L+       ++      
Sbjct: 191 YQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRM------ 244

Query: 204 LEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSHPALRRASR-------FAQ 256
           + E++E+ Q  V W      Q   E+L    S S   P+     L+   R          
Sbjct: 245 IAELKERSQRPVRWM----LQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREILKT 300

Query: 257 WAIHPTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERF-STSQVLCSQALSSGKHYW 315
           +A     +  +    L VS+D + V      Q    + ERF   + VL SQ +SSG+HYW
Sbjct: 301 YAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYW 360

Query: 316 EVDTRNCSHWAVGVASWEMSRDQVL 340
           EV+  + S W +GV    + R +V+
Sbjct: 361 EVEVGDRSEWGLGVCKQNVDRKEVV 385


>gi|89886468 fibronectin type III and SPRY domain containing 1-like
           isoform 1 [Homo sapiens]
          Length = 498

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 48/148 (32%), Positives = 74/148 (50%), Gaps = 8/148 (5%)

Query: 279 RTVTVSHRPQPYRWSCERFSTSQ--VLCSQALSSGKHYWEVDT-RNCSHWAVGVASWEMS 335
           +  +V  RP   R S +RF+     VL   A+ SG+HYWEV   ++C  ++VGVA   + 
Sbjct: 317 KRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLG 376

Query: 336 RDQVLGRTMDSCCVEWKGTSQ--LSAWHMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVD 393
           +   LG+T  S C+      Q   +A H  K   L    P  +G++ + + G+L+FY   
Sbjct: 377 KFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDA- 435

Query: 394 NQEKLLYECTISASSPLYPAF--WLYGL 419
           N ++LLY      + P+ P F  W  GL
Sbjct: 436 NSKQLLYSFKTKFTQPVLPGFMVWCGGL 463


>gi|223718222 fibronectin type III and SPRY domain containing 1-like
           isoform 3 [Homo sapiens]
          Length = 530

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 48/148 (32%), Positives = 74/148 (50%), Gaps = 8/148 (5%)

Query: 279 RTVTVSHRPQPYRWSCERFSTSQ--VLCSQALSSGKHYWEVDT-RNCSHWAVGVASWEMS 335
           +  +V  RP   R S +RF+     VL   A+ SG+HYWEV   ++C  ++VGVA   + 
Sbjct: 349 KRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLG 408

Query: 336 RDQVLGRTMDSCCVEWKGTSQ--LSAWHMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVD 393
           +   LG+T  S C+      Q   +A H  K   L    P  +G++ + + G+L+FY   
Sbjct: 409 KFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDA- 467

Query: 394 NQEKLLYECTISASSPLYPAF--WLYGL 419
           N ++LLY      + P+ P F  W  GL
Sbjct: 468 NSKQLLYSFKTKFTQPVLPGFMVWCGGL 495


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 107/473 (22%), Positives = 182/473 (38%), Gaps = 84/473 (17%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCL-----EALWGARDARRWACPTCRQGAAQQP 70
           ++++ C IC  LL  P +L CGHS CR C+     EA+       + +CP C    + + 
Sbjct: 10  QEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSM--GGKSSCPVCGISYSFE- 66

Query: 71  HLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSA----------AARPRRRP 120
           HL+ N  L ++ ++ +        G     C   G   L               R +   
Sbjct: 67  HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 126

Query: 121 ELQRVAVEKSITEVAQELTELVEHL-----------VDIVRS-------LQNQRPLSESG 162
               V  E+   E  ++L  +++ L            DI          +Q +R   ++ 
Sbjct: 127 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 186

Query: 163 PDNELSILGKAFSSGVDLSMASPKLVTSDTAAGK---------IRDILHDLE-------- 205
            D   SIL       +       K      A  +         +R+++ D+E        
Sbjct: 187 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 246

Query: 206 EIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSH--PALRRASRFAQWAIHPTF 263
           E+ + +   + W E    + + +++     +    PD S      R  +    + +  T 
Sbjct: 247 ELLQDMSGIMKWSEIWRLK-KPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 305

Query: 264 NLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTSQVLCSQALSSGKHYWEVDTRNCS 323
           N  +L+ +L +S+D R V +S    P++  C  +    VL SQ  SSGKHYWEVD    +
Sbjct: 306 NSVNLNLNLVLSEDQRQV-ISVPIWPFQ--CYNYG---VLGSQYFSSGKHYWEVDVSKKT 359

Query: 324 HWAVGVASWEMSRDQ--VLGRTMDSCCVEWKGTSQLSAW---------HMVKETVLGSD- 371
            W +GV     SR    V+ R  +   +  K       W         + V E  L SD 
Sbjct: 360 AWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDP 419

Query: 372 ---------RPGVVGIWLNLEEGKLAFYSVDNQEKLLYECT-ISASSPLYPAF 414
                     P  VG++L+ E G ++F++V +   L+Y+ +    S P+YP F
Sbjct: 420 EVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 472


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 107/473 (22%), Positives = 182/473 (38%), Gaps = 84/473 (17%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCL-----EALWGARDARRWACPTCRQGAAQQP 70
           ++++ C IC  LL  P +L CGHS CR C+     EA+       + +CP C    + + 
Sbjct: 10  QEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSM--GGKSSCPVCGISYSFE- 66

Query: 71  HLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSA----------AARPRRRP 120
           HL+ N  L ++ ++ +        G     C   G   L               R +   
Sbjct: 67  HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 126

Query: 121 ELQRVAVEKSITEVAQELTELVEHL-----------VDIVRS-------LQNQRPLSESG 162
               V  E+   E  ++L  +++ L            DI          +Q +R   ++ 
Sbjct: 127 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 186

Query: 163 PDNELSILGKAFSSGVDLSMASPKLVTSDTAAGK---------IRDILHDLE-------- 205
            D   SIL       +       K      A  +         +R+++ D+E        
Sbjct: 187 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 246

Query: 206 EIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSH--PALRRASRFAQWAIHPTF 263
           E+ + +   + W E    + + +++     +    PD S      R  +    + +  T 
Sbjct: 247 ELLQDMSGIMKWSEIWRLK-KPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 305

Query: 264 NLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTSQVLCSQALSSGKHYWEVDTRNCS 323
           N  +L+ +L +S+D R V +S    P++  C  +    VL SQ  SSGKHYWEVD    +
Sbjct: 306 NSVNLNLNLVLSEDQRQV-ISVPIWPFQ--CYNYG---VLGSQYFSSGKHYWEVDVSKKT 359

Query: 324 HWAVGVASWEMSRDQ--VLGRTMDSCCVEWKGTSQLSAW---------HMVKETVLGSD- 371
            W +GV     SR    V+ R  +   +  K       W         + V E  L SD 
Sbjct: 360 AWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDP 419

Query: 372 ---------RPGVVGIWLNLEEGKLAFYSVDNQEKLLYECT-ISASSPLYPAF 414
                     P  VG++L+ E G ++F++V +   L+Y+ +    S P+YP F
Sbjct: 420 EVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 472


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 107/473 (22%), Positives = 182/473 (38%), Gaps = 84/473 (17%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCL-----EALWGARDARRWACPTCRQGAAQQP 70
           ++++ C IC  LL  P +L CGHS CR C+     EA+       + +CP C    + + 
Sbjct: 364 QEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSM--GGKSSCPVCGISYSFE- 420

Query: 71  HLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSA----------AARPRRRP 120
           HL+ N  L ++ ++ +        G     C   G   L               R +   
Sbjct: 421 HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 480

Query: 121 ELQRVAVEKSITEVAQELTELVEHL-----------VDIVRS-------LQNQRPLSESG 162
               V  E+   E  ++L  +++ L            DI          +Q +R   ++ 
Sbjct: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540

Query: 163 PDNELSILGKAFSSGVDLSMASPKLVTSDTAAGK---------IRDILHDLE-------- 205
            D   SIL       +       K      A  +         +R+++ D+E        
Sbjct: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600

Query: 206 EIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSH--PALRRASRFAQWAIHPTF 263
           E+ + +   + W E    + + +++     +    PD S      R  +    + +  T 
Sbjct: 601 ELLQDMSGIMKWSEIWRLK-KPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 659

Query: 264 NLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTSQVLCSQALSSGKHYWEVDTRNCS 323
           N  +L+ +L +S+D R V +S    P++  C  +    VL SQ  SSGKHYWEVD    +
Sbjct: 660 NSVNLNLNLVLSEDQRQV-ISVPIWPFQ--CYNYG---VLGSQYFSSGKHYWEVDVSKKT 713

Query: 324 HWAVGVASWEMSRDQ--VLGRTMDSCCVEWKGTSQLSAW---------HMVKETVLGSD- 371
            W +GV     SR    V+ R  +   +  K       W         + V E  L SD 
Sbjct: 714 AWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDP 773

Query: 372 ---------RPGVVGIWLNLEEGKLAFYSVDNQEKLLYECT-ISASSPLYPAF 414
                     P  VG++L+ E G ++F++V +   L+Y+ +    S P+YP F
Sbjct: 774 EVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 8/75 (10%)

Query: 17  DDLGCIICQGLLDWPATLPCGHSFCRHCL-----EALWGARDARRWACPTCRQGAAQQPH 71
           +++ C IC  LL  P ++ CGHSFC+ C+     E++ G    R  +CP C Q + Q  +
Sbjct: 39  EEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGER--SCPVC-QTSYQPGN 95

Query: 72  LRKNTLLQDLADKYR 86
           LR N  L ++  + R
Sbjct: 96  LRPNRHLANIVRRLR 110


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 106/445 (23%), Positives = 173/445 (38%), Gaps = 61/445 (13%)

Query: 36  CGHSFCRHCLEALW----GARDARR----WACPTCRQGAAQQPHL--RKNTLLQDLADKY 85
           CGH+FCR C++  W    G +  R+    + CP CR+ + Q+  L  R  T + ++A ++
Sbjct: 4   CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQH 63

Query: 86  RRAARE--IQAGSDPAHCPCPGSSSLSSAAARPRRRPELQRVA-VEKSITEVAQELTELV 142
               ++   Q   +P    C    S      R  R   L RV   E+++     +L E +
Sbjct: 64  PGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDM 123

Query: 143 EHLVDIVRSLQNQRPLSESG--------PDNELSILGKAFSSGVDLSMASPKLVTS---- 190
           E+L + +    N +   E           +    I+ +     + L     +L+ +    
Sbjct: 124 EYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETE 183

Query: 191 -DTAAGKIRDIL-------HDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPD 242
            +  A ++R+ +       H LE +  +L+E  T       Q   E L   ++ S   P+
Sbjct: 184 EEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPE 243

Query: 243 QSHPALRRASRFAQWAIH----------PTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRW 292
            + P   R        I           P          L  S+  R +  S     +  
Sbjct: 244 VAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEGSGF-C 302

Query: 293 SCERFSTSQVLCSQ-ALSSGKHYWEV--DTRNCSHWAVGVASWEMSRDQVLGRTMDSCCV 349
           S +RF        Q A SSG+HYWEV  +    + WA+GV      RD V  +     C 
Sbjct: 303 SKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVC-----RDNVSRKDRVPKCP 357

Query: 350 E---W-----KGTSQLSAWHMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYE 401
           E   W     KGT  LS +  +   +L  + P  +GI+L+ E G+++FYSV +   L   
Sbjct: 358 ENGFWVVQLSKGTKYLSTFSALTPVML-MEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTY 416

Query: 402 CTISASSPLYPAFWLYGLHPGNYLI 426
              +   PL P F L     G  +I
Sbjct: 417 SQATFPGPLQPFFCLGAPKSGQMVI 441


>gi|239755486 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 13/225 (5%)

Query: 201 LHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSHPALRR------ASRF 254
           L  ++++  +L E+    +    Q  G +      +  P P   +P L            
Sbjct: 220 LEGMKDMYRELWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWCITGVLDML 279

Query: 255 AQWAIHPTFNLKSLSCSLEVSKDSRTVTVS--HRPQPYRWSCERFSTSQVLCSQALSSGK 312
             + +    + +   C + +S+D R V     HR  P     +   +  V C+QA +SGK
Sbjct: 280 NNFRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPM--DPQGVESFAVWCAQAFTSGK 337

Query: 313 HYWEVDTRNCSHWAVGVASWEMSRDQ--VLGRTMDSCCVEWKGTSQLSAWHMVKETVLGS 370
           HYWEVD  + S+W +GV     + D   V+        +  K ++  S        +   
Sbjct: 338 HYWEVDVTHSSNWILGVCRDSRTADTNIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYV 397

Query: 371 DRP-GVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAF 414
            RP G VG++L+ + G ++F+ V     +      S SSPL P F
Sbjct: 398 QRPLGWVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFF 442



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 16 EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
          +++L C IC      P T  C HSFCR CL  L          CP CR+  +++P+   N
Sbjct: 10 QNELICCICVNYFIDPVTTDCVHSFCRPCL-CLCSEEGRAPMRCPLCRK-ISEKPNFNTN 67

Query: 76 TLLQDLADKYRRAAREIQAGSD 97
            L+ LA   R+   +    SD
Sbjct: 68 VALKKLASLARQTRPQNINSSD 89


>gi|239755484 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 450

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 13/225 (5%)

Query: 201 LHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSHPALRR------ASRF 254
           L  ++++  +L E+    +    Q  G +      +  P P   +P L            
Sbjct: 223 LEGMKDMYRELWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWCITGVLDML 282

Query: 255 AQWAIHPTFNLKSLSCSLEVSKDSRTVTVS--HRPQPYRWSCERFSTSQVLCSQALSSGK 312
             + +    + +   C + +S+D R V     HR  P     +   +  V C+QA +SGK
Sbjct: 283 NNFRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPM--DPQGVESFAVWCAQAFTSGK 340

Query: 313 HYWEVDTRNCSHWAVGVASWEMSRDQ--VLGRTMDSCCVEWKGTSQLSAWHMVKETVLGS 370
           HYWEVD  + S+W +GV     + D   V+        +  K ++  S        +   
Sbjct: 341 HYWEVDVTHSSNWILGVCRDSRTADTNIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYV 400

Query: 371 DRP-GVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAF 414
            RP G VG++L+ + G ++F+ V     +      S SSPL P F
Sbjct: 401 QRPLGWVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFF 445



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 16 EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
          +++L C IC      P T  C HSFCR CL  L          CP CR+  +++P+   N
Sbjct: 10 QNELICCICVNYFIDPVTTDCVHSFCRPCL-CLCSEEGRAPMRCPLCRK-ISEKPNFNTN 67

Query: 76 TLLQDLADKYRRAAREIQAGSD 97
            L+ LA   R+   +    SD
Sbjct: 68 VALKKLASLARQTRPQNINSSD 89


>gi|239750044 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 13/225 (5%)

Query: 201 LHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSHPALRR------ASRF 254
           L  ++++  +L E+    +    Q  G +      +  P P   +P L            
Sbjct: 220 LEGMKDMYRELWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWCITGVLDML 279

Query: 255 AQWAIHPTFNLKSLSCSLEVSKDSRTVTVS--HRPQPYRWSCERFSTSQVLCSQALSSGK 312
             + +    + +   C + +S+D R V     HR  P     +   +  V C+QA +SGK
Sbjct: 280 NNFRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPM--DPQGVESFAVWCAQAFTSGK 337

Query: 313 HYWEVDTRNCSHWAVGVASWEMSRDQ--VLGRTMDSCCVEWKGTSQLSAWHMVKETVLGS 370
           HYWEVD  + S+W +GV     + D   V+        +  K ++  S        +   
Sbjct: 338 HYWEVDVTHSSNWILGVCRDSRTADTNIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYV 397

Query: 371 DRP-GVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAF 414
            RP G VG++L+ + G ++F+ V     +      S SSPL P F
Sbjct: 398 QRPLGWVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFF 442



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 16 EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
          +++L C IC      P T  C HSFCR CL  L          CP CR+  +++P+   N
Sbjct: 10 QNELICCICVNYFIDPVTTDCVHSFCRPCL-CLCSEEGRAPMRCPLCRK-ISEKPNFNTN 67

Query: 76 TLLQDLADKYRRAAREIQAGSD 97
            L+ LA   R+   +    SD
Sbjct: 68 VALKKLASLARQTRPQNINSSD 89


>gi|239750042 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 450

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 13/225 (5%)

Query: 201 LHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSHPALRR------ASRF 254
           L  ++++  +L E+    +    Q  G +      +  P P   +P L            
Sbjct: 223 LEGMKDMYRELWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWCITGVLDML 282

Query: 255 AQWAIHPTFNLKSLSCSLEVSKDSRTVTVS--HRPQPYRWSCERFSTSQVLCSQALSSGK 312
             + +    + +   C + +S+D R V     HR  P     +   +  V C+QA +SGK
Sbjct: 283 NNFRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPM--DPQGVESFAVWCAQAFTSGK 340

Query: 313 HYWEVDTRNCSHWAVGVASWEMSRDQ--VLGRTMDSCCVEWKGTSQLSAWHMVKETVLGS 370
           HYWEVD  + S+W +GV     + D   V+        +  K ++  S        +   
Sbjct: 341 HYWEVDVTHSSNWILGVCRDSRTADTNIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYV 400

Query: 371 DRP-GVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAF 414
            RP G VG++L+ + G ++F+ V     +      S SSPL P F
Sbjct: 401 QRPLGWVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFF 445



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 16 EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
          +++L C IC      P T  C HSFCR CL  L          CP CR+  +++P+   N
Sbjct: 10 QNELICCICVNYFIDPVTTDCVHSFCRPCL-CLCSEEGRAPMRCPLCRK-ISEKPNFNTN 67

Query: 76 TLLQDLADKYRRAAREIQAGSD 97
            L+ LA   R+   +    SD
Sbjct: 68 VALKKLASLARQTRPQNINSSD 89


>gi|239744355 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 447

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 13/225 (5%)

Query: 201 LHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSHPALRR------ASRF 254
           L  ++++  +L E+    +    Q  G +      +  P P   +P L            
Sbjct: 220 LEGMKDMYRELWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWCITGVLDML 279

Query: 255 AQWAIHPTFNLKSLSCSLEVSKDSRTVTVS--HRPQPYRWSCERFSTSQVLCSQALSSGK 312
             + +    + +   C + +S+D R V     HR  P     +   +  V C+QA +SGK
Sbjct: 280 NNFRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPM--DPQGVESFAVWCAQAFTSGK 337

Query: 313 HYWEVDTRNCSHWAVGVASWEMSRDQ--VLGRTMDSCCVEWKGTSQLSAWHMVKETVLGS 370
           HYWEVD  + S+W +GV     + D   V+        +  K ++  S        +   
Sbjct: 338 HYWEVDVTHSSNWILGVCRDSRTADTNIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYV 397

Query: 371 DRP-GVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAF 414
            RP G VG++L+ + G ++F+ V     +      S SSPL P F
Sbjct: 398 QRPLGWVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFF 442



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 16 EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
          +++L C IC      P T  C HSFCR CL  L          CP CR+  +++P+   N
Sbjct: 10 QNELICCICVNYFIDPVTTDCVHSFCRPCL-CLCSEEGRAPMRCPLCRK-ISEKPNFNTN 67

Query: 76 TLLQDLADKYRRAAREIQAGSD 97
            L+ LA   R+   +    SD
Sbjct: 68 VALKKLASLARQTRPQNINSSD 89


>gi|239744353 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 450

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 13/225 (5%)

Query: 201 LHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPLPDQSHPALRR------ASRF 254
           L  ++++  +L E+    +    Q  G +      +  P P   +P L            
Sbjct: 223 LEGMKDMYRELWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWCITGVLDML 282

Query: 255 AQWAIHPTFNLKSLSCSLEVSKDSRTVTVS--HRPQPYRWSCERFSTSQVLCSQALSSGK 312
             + +    + +   C + +S+D R V     HR  P     +   +  V C+QA +SGK
Sbjct: 283 NNFRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPM--DPQGVESFAVWCAQAFTSGK 340

Query: 313 HYWEVDTRNCSHWAVGVASWEMSRDQ--VLGRTMDSCCVEWKGTSQLSAWHMVKETVLGS 370
           HYWEVD  + S+W +GV     + D   V+        +  K ++  S        +   
Sbjct: 341 HYWEVDVTHSSNWILGVCRDSRTADTNIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYV 400

Query: 371 DRP-GVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAF 414
            RP G VG++L+ + G ++F+ V     +      S SSPL P F
Sbjct: 401 QRPLGWVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFF 445



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 16 EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
          +++L C IC      P T  C HSFCR CL  L          CP CR+  +++P+   N
Sbjct: 10 QNELICCICVNYFIDPVTTDCVHSFCRPCL-CLCSEEGRAPMRCPLCRK-ISEKPNFNTN 67

Query: 76 TLLQDLADKYRRAAREIQAGSD 97
            L+ LA   R+   +    SD
Sbjct: 68 VALKKLASLARQTRPQNINSSD 89


>gi|46409324 SPRY domain containing 4 [Homo sapiens]
          Length = 207

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 53/175 (30%), Positives = 78/175 (44%), Gaps = 13/175 (7%)

Query: 251 ASRFAQWAIHPTFNLKSLSCSLEVSKDSRTVT---VSHRPQPYRWSCERFST-SQVLCSQ 306
           AS  AQ  +      K+   SL + +D   V    V   P     + ERF   + VL   
Sbjct: 22  ASTEAQRGVSFKLEEKTAHSSLALFRDDTGVKYGLVGLEPTKVALNVERFREWAVVLADT 81

Query: 307 ALSSGKHYWEVDTRNCSHWAVGVASWEMSRDQVLGRTMDSCCVEWKGTSQLSAWHMV--- 363
           A++SG+HYWEV  +    + +GVA  +MSRD  +G    S    W  T     W+ +   
Sbjct: 82  AVTSGRHYWEVTVKRSQQFRIGVADVDMSRDSCIGVDDRS----WVFTYAQRKWYTMLAN 137

Query: 364 -KETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAFWLY 417
            K  V G  +P  VG+ L  E  KL+   V +Q  +++        P+ PAF L+
Sbjct: 138 EKAPVEGIGQPEKVGLLLEYEAQKLSLVDV-SQVSVVHTLQTDFRGPVVPAFALW 191


>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
          Length = 551

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 3/86 (3%)

Query: 16  EDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKN 75
           E++L C IC  +   P  LPC H+FCR C+   W A+D+    CP C Q   Q+P L KN
Sbjct: 10  EEELICPICLHVFVEPVQLPCKHNFCRGCIGEAW-AKDSGLVRCPECNQAYNQKPGLEKN 68

Query: 76  TLLQDLADKYRRAAREIQAGSDPAHC 101
             L ++ +K+   A  ++      HC
Sbjct: 69  LKLTNIVEKFN--ALHVEKPPAALHC 92


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.131    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,984,516
Number of Sequences: 37866
Number of extensions: 817676
Number of successful extensions: 3900
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 232
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 3400
Number of HSP's gapped (non-prelim): 522
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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