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Search of human proteins with 37537696
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37537696 M-phase phosphoprotein 9 [Homo sapiens]
(1031 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37537696 M-phase phosphoprotein 9 [Homo sapiens] 2043 0.0
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 66 2e-10
gi|34577114 cytomatrix protein p110 [Homo sapiens] 60 8e-09
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 58 4e-08
gi|7705415 hook homolog 1 [Homo sapiens] 57 7e-08
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 56 2e-07
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 56 2e-07
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 56 2e-07
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 56 2e-07
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 56 2e-07
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 56 2e-07
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 56 2e-07
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 56 2e-07
gi|157785668 coiled-coil domain containing 39 [Homo sapiens] 55 3e-07
gi|71061468 centromere protein E [Homo sapiens] 54 6e-07
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 54 8e-07
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 54 1e-06
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 54 1e-06
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 54 1e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 53 2e-06
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 52 2e-06
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 52 2e-06
gi|93102364 SWAP-70 protein [Homo sapiens] 52 3e-06
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 52 4e-06
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 52 4e-06
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 52 4e-06
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 51 5e-06
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 51 5e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 51 6e-06
gi|55749708 outer dense fiber of sperm tails 2-like isoform b [H... 51 6e-06
>gi|37537696 M-phase phosphoprotein 9 [Homo sapiens]
Length = 1031
Score = 2043 bits (5294), Expect = 0.0
Identities = 1031/1031 (100%), Positives = 1031/1031 (100%)
Query: 1 MGFFSLSSERNESVIHYPESTEPEIQQEMSTSQPDCNVDSCSVSSGYGTFCISELNLYKS 60
MGFFSLSSERNESVIHYPESTEPEIQQEMSTSQPDCNVDSCSVSSGYGTFCISELNLYKS
Sbjct: 1 MGFFSLSSERNESVIHYPESTEPEIQQEMSTSQPDCNVDSCSVSSGYGTFCISELNLYKS 60
Query: 61 KDPKEFMEHIDVPKGQYVAPAVPAESLVDGVKNENFYIQTPEECHVSLKEDVSISPGEFE 120
KDPKEFMEHIDVPKGQYVAPAVPAESLVDGVKNENFYIQTPEECHVSLKEDVSISPGEFE
Sbjct: 61 KDPKEFMEHIDVPKGQYVAPAVPAESLVDGVKNENFYIQTPEECHVSLKEDVSISPGEFE 120
Query: 121 HNFLGENKVSEVYSGKTNSNAITSWAQKLKQNQPKRAHVEDGGSRSKQGNEQSKKTPIEK 180
HNFLGENKVSEVYSGKTNSNAITSWAQKLKQNQPKRAHVEDGGSRSKQGNEQSKKTPIEK
Sbjct: 121 HNFLGENKVSEVYSGKTNSNAITSWAQKLKQNQPKRAHVEDGGSRSKQGNEQSKKTPIEK 180
Query: 181 SDFAAATHPRAFYLSKPDETPNAWMSDSGTGLTYWKLEEKDMHHSLPETLEKTFISLSST 240
SDFAAATHPRAFYLSKPDETPNAWMSDSGTGLTYWKLEEKDMHHSLPETLEKTFISLSST
Sbjct: 181 SDFAAATHPRAFYLSKPDETPNAWMSDSGTGLTYWKLEEKDMHHSLPETLEKTFISLSST 240
Query: 241 DVSPNQSNTSNEMKLPSLKDIYYKKQRENKQLPERNLTSASNPNHPPEVLTLDPTLHMKP 300
DVSPNQSNTSNEMKLPSLKDIYYKKQRENKQLPERNLTSASNPNHPPEVLTLDPTLHMKP
Sbjct: 241 DVSPNQSNTSNEMKLPSLKDIYYKKQRENKQLPERNLTSASNPNHPPEVLTLDPTLHMKP 300
Query: 301 KQQISGIQPHGLPNALDDRISFSPDSVLEPSMSSPSDIDSFSQASNVTSQLPGFPKYPSH 360
KQQISGIQPHGLPNALDDRISFSPDSVLEPSMSSPSDIDSFSQASNVTSQLPGFPKYPSH
Sbjct: 301 KQQISGIQPHGLPNALDDRISFSPDSVLEPSMSSPSDIDSFSQASNVTSQLPGFPKYPSH 360
Query: 361 TKASPVDSWKNQTFQNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQSQLPG 420
TKASPVDSWKNQTFQNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQSQLPG
Sbjct: 361 TKASPVDSWKNQTFQNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQSQLPG 420
Query: 421 TANSVPECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISG 480
TANSVPECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISG
Sbjct: 421 TANSVPECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISG 480
Query: 481 VEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKIL 540
VEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKIL
Sbjct: 481 VEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKIL 540
Query: 541 QERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEY 600
QERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEY
Sbjct: 541 QERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEY 600
Query: 601 ESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIH 660
ESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIH
Sbjct: 601 ESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIH 660
Query: 661 VRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKD 720
VRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKD
Sbjct: 661 VRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKD 720
Query: 721 SSPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSV 780
SSPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSV
Sbjct: 721 SSPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSV 780
Query: 781 NASRSPEKCAQQRQKRLNSASQRSSSLPPSNRKSSTPTKREIMLTPVTVAYSPKRSPKEN 840
NASRSPEKCAQQRQKRLNSASQRSSSLPPSNRKSSTPTKREIMLTPVTVAYSPKRSPKEN
Sbjct: 781 NASRSPEKCAQQRQKRLNSASQRSSSLPPSNRKSSTPTKREIMLTPVTVAYSPKRSPKEN 840
Query: 841 LSPGFSHLLSKNESSPIRFDILLDDLDTVPVSTLQRTNPRKQLQFLPLDDSEEKTYSEKA 900
LSPGFSHLLSKNESSPIRFDILLDDLDTVPVSTLQRTNPRKQLQFLPLDDSEEKTYSEKA
Sbjct: 841 LSPGFSHLLSKNESSPIRFDILLDDLDTVPVSTLQRTNPRKQLQFLPLDDSEEKTYSEKA 900
Query: 901 TDNHVNHSSCPEPVPNGVKKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFEYTAKIRTLA 960
TDNHVNHSSCPEPVPNGVKKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFEYTAKIRTLA
Sbjct: 901 TDNHVNHSSCPEPVPNGVKKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFEYTAKIRTLA 960
Query: 961 ETERFFDELTKEKDQIEAALSRMPSPGGRITLQTRLNQEALEDRLERINRELGSVRMTLK 1020
ETERFFDELTKEKDQIEAALSRMPSPGGRITLQTRLNQEALEDRLERINRELGSVRMTLK
Sbjct: 961 ETERFFDELTKEKDQIEAALSRMPSPGGRITLQTRLNQEALEDRLERINRELGSVRMTLK 1020
Query: 1021 KFHVLRTSANL 1031
KFHVLRTSANL
Sbjct: 1021 KFHVLRTSANL 1031
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 65.9 bits (159), Expect = 2e-10
Identities = 85/410 (20%), Positives = 174/410 (42%), Gaps = 42/410 (10%)
Query: 427 ECISLTSLEDPVILSKIRQNLKEK-HARHIADLRAYYESEINSLKQKLEA---------- 475
E + + +L D + L + R++ K K + + A E+ I+ L+ +L
Sbjct: 229 ELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQ 288
Query: 476 ---KEISGVEDWKITNQILVDRC-------GQLDSALHEATSRVRTLENKNNLLEIEVND 525
K S V + NQ L + +L+ +E + + ++ + +++
Sbjct: 289 ELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQ 348
Query: 526 LRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEA- 584
L+ R SA+ ++ + + E ++++ + ++++ Q L+ F+ + ++KE
Sbjct: 349 LQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQH 408
Query: 585 --QLKQE-NKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQ 641
QL+ E N++ LL LG+ H R+K+ + KL+D Q++DL+ +S+LE Q
Sbjct: 409 GLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQ 468
Query: 642 VKQVEHENMLSLRHN-SRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSN 700
+K+ + N L+H + + L S ++ + E + D + N
Sbjct: 469 LKE-KVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQN 527
Query: 701 VDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIFKNWG 760
++ L++ S + S LEK+ L K Q +T ++ L+E KN
Sbjct: 528 LEALLQK--SKENISLLEKERE------DLYAKIQAGEGETAVLNQLQE-------KNHT 572
Query: 761 TQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQRSSSLPPS 810
Q + + Q+E+ A + Q+++ L +A R SL S
Sbjct: 573 LQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETS 622
Score = 45.8 bits (107), Expect = 2e-04
Identities = 73/374 (19%), Positives = 145/374 (38%), Gaps = 33/374 (8%)
Query: 427 ECISLTSLEDPVILSKIRQNLKEKHA-RHIADLRAYYESEINSLKQKLEAKEISGVEDWK 485
E ISL E + +KI+ E + + + ++ L +KL+ + E K
Sbjct: 537 ENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQS----ESHK 592
Query: 486 ITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIE 545
+ L D+ + + L A RV +LE N L ++N+ +E+ S K E +
Sbjct: 593 QAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELL- 651
Query: 546 EMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGK 605
S E T R DL+ + A DK+ +L + + + + +
Sbjct: 652 ----LSAEAAKTAQRA-----DLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQE 702
Query: 606 EHRRVKDALNTTENKLLDAYTQISDLKRMISKLEA---QVKQVEHENMLSLRHNSRIHVR 662
+++ L + K L + +L+ I KLEA +VK + + + L+ +++
Sbjct: 703 HCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTD 762
Query: 663 PSRANTLATSDVSRRKWLIPGAEYSI-FTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDS 721
T + + K ++ + + L++ + Q EE + L++D
Sbjct: 763 LELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEE------KQILKQDF 816
Query: 722 SPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVN 781
S T K Q E + I + EL + K+ K + + S + + ++ S +
Sbjct: 817 ETLSQET----KIQHEELNNRIQTTVTELQKVKMEK----EALMTELSTVKDKLSKVSDS 868
Query: 782 ASRSPEKCAQQRQK 795
S + ++ QK
Sbjct: 869 LKNSKSEFEKENQK 882
Score = 37.4 bits (85), Expect = 0.073
Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 36/218 (16%)
Query: 467 NSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLEN-KNNLLEIEVND 525
N L Q+L+ + + +D Q L +RC L E + + + L N K+ L EIE
Sbjct: 1074 NKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIK 1133
Query: 526 LRERFSAASSASKILQERIEEMR--TSSKEKDNTIIRLKSRLQD--------LEEAFENA 575
R+ ++ ++E ++ T+ K+ +I+ K LQ +E+ N
Sbjct: 1134 CRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQ 1193
Query: 576 YKLSD--------------DKEAQLKQENKMFQDLLGEYE-----------SLGKEHRRV 610
L D +KEA+L E K + + ++E +L + V
Sbjct: 1194 QILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTV 1253
Query: 611 KDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHE 648
K +++ ++ + Q DL+ I+ LEA V+ + E
Sbjct: 1254 KKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDE 1291
Score = 37.0 bits (84), Expect = 0.096
Identities = 40/222 (18%), Positives = 97/222 (43%), Gaps = 26/222 (11%)
Query: 429 ISLTSLEDPVILSK--IRQNLKEKHARHIADLRAYYESEINSLKQKLEAK--EISGVEDW 484
+ L S+++ +I ++ ++QN KE+ + IN LKQ E K +I ++
Sbjct: 931 LELNSMQEQLIQAQNTLKQNEKEEQQ---------LQGNINELKQSSEQKKKQIEALQ-- 979
Query: 485 KITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERI 544
G+L A+ + T L+ + E+ +E+ S + + QE
Sbjct: 980 -----------GELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETF 1028
Query: 545 EEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLG 604
+++++ +++ ++ + L+ +EE A + Q+ +NK+ Q+L +L
Sbjct: 1029 KQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLE 1088
Query: 605 KEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVE 646
++ + + L L D + S ++ + ++++ ++E
Sbjct: 1089 QDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIE 1130
Score = 30.4 bits (67), Expect = 9.0
Identities = 95/494 (19%), Positives = 182/494 (36%), Gaps = 56/494 (11%)
Query: 539 ILQERIEEMRTSSKEKDNTIIRLKSRL---QDLEEAFENAYKLSDDKEAQLKQENKMFQD 595
+L++ +++++ S KE+ LK L Q L++ L D A+L Q
Sbjct: 87 LLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAEL-------QS 139
Query: 596 LLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRH 655
L + E E+ +K + E K T+I+D+K SK + + E R
Sbjct: 140 LEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIK---SKYDEERSLREAAEQKVTRL 196
Query: 656 NSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQL--EETCSLGH 713
++ + L T + R PG E + L + +DN E S
Sbjct: 197 TEELNKEATVIQDLKTELLQR-----PGIEDVAVLKKELVQVQTLMDNMTLERERESEKL 251
Query: 714 RSPLEKDSSPGSSSTSLLIKKQRETSDTP--IMRALKELDEGKIFKNWGTQTEKEDTSNI 771
+ +K S +SS + + + + E + P + ++EL + K N TQ + T N+
Sbjct: 252 KDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENL 311
Query: 772 NPRQTETSVNASRSPEKCAQQRQKRLNSASQRSSSLPPSNRKSSTPTKREIMLTPVTVAY 831
++ + + + E+ ++ + + +R S++ T L + V
Sbjct: 312 LKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETS----LHRIHVEL 367
Query: 832 SPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDTVPVSTLQRTNPRKQLQFLPLDDS 891
S K + L S + +K + F L + LQ + QL L+
Sbjct: 368 SEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLE-- 425
Query: 892 EEKTYSEKATDNHVNHSSCPEPVPNGVKKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFE 951
E+ E H E +++S +K + V+ Q K + Q +
Sbjct: 426 TERQLGEA-------HGRLKEQ-----RQLSSEKLMDKEQQVADLQLKLSRLEEQLKE-- 471
Query: 952 YTAKIRTLAETERFFDELTKEKDQIEAALSRMPSPGGRITLQTRLNQEALEDRLERINRE 1011
K+ E + D+ TK++ Q + AL + T ++ LE++ R+
Sbjct: 472 ---KVTNSTELQHQLDK-TKQQHQEQQALQQ----------STTAKLREAQNDLEQVLRQ 517
Query: 1012 LGSVRMTLKKFHVL 1025
+G ++ L
Sbjct: 518 IGDKDQKIQNLEAL 531
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 60.5 bits (145), Expect = 8e-09
Identities = 50/219 (22%), Positives = 101/219 (46%), Gaps = 21/219 (9%)
Query: 440 LSKIRQNLKEKHARHIADLRAYYESEINS---LKQKLEA--KEISGVEDWKITNQILVD- 493
+ +++Q L +K + +A L+ E+ N KQ +E + ++ E Q VD
Sbjct: 436 IDQLKQELSKKESELLA-LQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDA 494
Query: 494 ---RCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTS 550
R + +S L++ T +++ L + L E+ D+++ +LQ++IE ++
Sbjct: 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQ 554
Query: 551 SKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDL-----------LGE 599
++KD + LK R++ L+ N E L ++ ++ + L L E
Sbjct: 555 LRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEE 614
Query: 600 YESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKL 638
ES KE++ +K+ +N + +L + + + DLK S L
Sbjct: 615 IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSL 653
Score = 48.1 bits (113), Expect = 4e-05
Identities = 51/217 (23%), Positives = 94/217 (43%), Gaps = 52/217 (23%)
Query: 453 RHIADLRAYYESEINSLKQ------KLEAKEISGVEDWKITNQILVDRCGQLDSALHEAT 506
R+I DL E EI LK + +EI +E +K ++ + + QL L +
Sbjct: 392 RNIRDL----EDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKE 447
Query: 507 S-------RVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTII 559
S ++ TL N+N+ + + L+E +A + ILQ ++ +R +
Sbjct: 448 SELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALR----------L 497
Query: 560 RLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDAL----- 614
RL ++KE+ L ++ K QDL E +L E R +KD L
Sbjct: 498 RL------------------EEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKER 539
Query: 615 --NTTENKLLDAYTQISDLKRMISKLEAQVKQVEHEN 649
N + K+ + Q+ D + ++ L+ +VK ++ ++
Sbjct: 540 KINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDS 576
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 58.2 bits (139), Expect = 4e-08
Identities = 89/391 (22%), Positives = 164/391 (41%), Gaps = 40/391 (10%)
Query: 448 KEKHARHIADLRAYYESEINSLKQKLE--AKEISGV----EDWKITNQILVDRCGQLDSA 501
+EK+ + +A +RA E+ + ++++ + A+E+ + E K+ ++L +R +
Sbjct: 1473 REKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKV--KVLEER-QRFQEE 1529
Query: 502 LHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRL 561
+ T++V LE +V +L ++ + + ASK+ Q++++ ++ E RL
Sbjct: 1530 RQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRL 1589
Query: 562 KSRLQDL-------EEAFENAYKLSDDKEAQ----LKQENKMFQDLLGEYESLGKEHRRV 610
+++L +L E+A E+ YKL +K KQ+N+ Q+ L E L KE++ +
Sbjct: 1590 QAQLNELQAQLSQKEQAAEH-YKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKEL 1648
Query: 611 KDALNTTENKLLDAYTQISDLKRMISKLEAQVK----QVEHENMLSLRHNSRIHVRPSRA 666
+ ++L A + + ++ L AQV+ QV H + LR + V
Sbjct: 1649 RAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ-QLRDLGKFQVATDAL 1707
Query: 667 NTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEETCSLGH-RSPLEKDSSPG- 724
+ + I + S G PL Q + T G SP+ + P
Sbjct: 1708 KSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKV 1767
Query: 725 SSSTSLLIKKQRETSDTPIMRALKELDEGKIFKNWGTQT---EKEDTSNINPRQTE---- 777
S SL S P+ +L L G +F + G +T + T IN T+
Sbjct: 1768 ESLESLYFTPIPARSQAPLESSLDSL--GDVFLDSGRKTRSARRRTTQIINITMTKKLDV 1825
Query: 778 ---TSVNASRSPEKCAQQRQKRLNSASQRSS 805
S N+S + A Q L + S S
Sbjct: 1826 EEPDSANSSFYSTRSAPASQASLRATSSTQS 1856
Score = 37.0 bits (84), Expect = 0.096
Identities = 38/195 (19%), Positives = 80/195 (41%), Gaps = 14/195 (7%)
Query: 465 EINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVN 524
E S Q+L+ E+ Q +++ QL+ L A + LE KN +L+ +++
Sbjct: 329 EFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLS 388
Query: 525 DLRERFSAASS---------ASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENA 575
L E S +LQ + ++ +NT ++ + + + E + A
Sbjct: 389 QLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEA 448
Query: 576 YKLSD--DKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKR 633
L++ E + +Q + + DL +L + ++ A +L Q++ L
Sbjct: 449 KLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLT---AQVASLTS 505
Query: 634 MISKLEAQVKQVEHE 648
++ L A ++Q + E
Sbjct: 506 ELTTLNATIQQQDQE 520
Score = 36.2 bits (82), Expect = 0.16
Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 11/159 (6%)
Query: 497 QLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDN 556
+L H+A +R LE + N+ S AS ILQ +MR K+ +
Sbjct: 167 ELSPPSHQAKREIRFLELQKVASSSSGNNFLSG-SPASPMGDILQTPQFQMRRLKKQLAD 225
Query: 557 TIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDL--LGEYESLG----KEHRRV 610
+S +LE KL +K+AQ+ + L L E ++ KE +
Sbjct: 226 E----RSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEEL 281
Query: 611 KDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHEN 649
+D + +L + Q DLK S+++ ++ Q+ EN
Sbjct: 282 RDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEEN 320
Score = 34.3 bits (77), Expect = 0.62
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 34/237 (14%)
Query: 440 LSKIRQNLKEKHARHIADL----------RAYYESEINSLKQK-LEAKEISGVEDWKITN 488
L+ ++Q KEK A+ L R E +SLKQK + KE++ ++ +
Sbjct: 521 LAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQD 580
Query: 489 --QILVDRCGQLDSALHEATSRVRTLE----NKNNLLEIEVNDLR----ERFSAASSASK 538
Q L + +++L E + ++ LE K LEI L+ R SA +S ++
Sbjct: 581 HAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQ 640
Query: 539 ILQER------IEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKM 592
+E+ +EE++ + ++++ +LE + + + +KE ++++++
Sbjct: 641 AQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQL 700
Query: 593 FQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHEN 649
+ L ESL + K +L + + DA + + +R IS+L+A+ + + ++
Sbjct: 701 QEQLQALKESL----KVTKGSLEEEKRRAADA---LEEQQRCISELKAETRSLVEQH 750
Score = 30.8 bits (68), Expect = 6.9
Identities = 50/264 (18%), Positives = 110/264 (41%), Gaps = 25/264 (9%)
Query: 400 VDEENTVMVASASVSQSQLPGTANSVPECISLTSLEDPVILSKIRQ--NLKEKHARHIAD 457
++E+N ++ S + L ++ P+ E +L + Q LK++ A A+
Sbjct: 376 LEEKNEILQGKLSQLEEHLSQLQDNPPQ-------EKGEVLGDVLQLETLKQEAATLAAN 428
Query: 458 ---LRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLEN 514
L+A E + + + + EAK ++ ++ Q L L S++ + LE
Sbjct: 429 NTQLQARVEM-LETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQ 487
Query: 515 KNNL----LEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEE 570
+ L +V L + ++ + + + ++ +KEK +L LQ E+
Sbjct: 488 ASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQ---AQLAQTLQQQEQ 544
Query: 571 AFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEH-RRVKDALNTTENKLLDAYTQIS 629
A + + + LKQ+ + +++ + E+ ++H +++ A E L + +
Sbjct: 545 ASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALK 604
Query: 630 DL----KRMISKLEAQVKQVEHEN 649
L K +KLE +Q++ N
Sbjct: 605 QLEALEKEKAAKLEILQQQLQVAN 628
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 57.4 bits (137), Expect = 7e-08
Identities = 59/271 (21%), Positives = 122/271 (45%), Gaps = 27/271 (9%)
Query: 425 VPECISLTSLEDPVILSKIRQNL---------KEKHARHIADLRAYYESEINSLKQKLEA 475
+P+ +T DPV L ++ Q + K++H ++I L + + + Q+L +
Sbjct: 102 IPDLNQITECSDPVELGRLLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMS 161
Query: 476 KEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASS 535
KEI ++ L+ L EA + L + L+++V L++ ++ S
Sbjct: 162 KEILSSPPNDAVGELEQQLKRALEE-LQEALAEKEELRQRCEELDMQVTTLQDEKNSLVS 220
Query: 536 ASKILQERIEEMRTSSKEKDNTIIRLK---SRLQDLEEAFENAYKLSDDKE------AQL 586
++++ E+++++ S + NT++ K ++LQ LE+ E ++L K+ +L
Sbjct: 221 ENEMMNEKLDQL-DGSFDDPNTVVAKKYFHAQLQ-LEQLQEENFRLEAAKDDYRVHCEEL 278
Query: 587 KQENKMFQDLLGEYESLGKEHRRVKDALNTTE------NKLLDAYTQISDLKRMISKLEA 640
+++ FQ E SL +E R +KD ++ NKL + ++ L
Sbjct: 279 EKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRK 338
Query: 641 QVKQVEHENMLSLRHNSRIHVRPSRANTLAT 671
QVK ++ NM+ + + + +AN T
Sbjct: 339 QVKTLQETNMMYMHNTVSLEEELKKANAART 369
Score = 48.1 bits (113), Expect = 4e-05
Identities = 64/274 (23%), Positives = 119/274 (43%), Gaps = 41/274 (14%)
Query: 433 SLEDPVILSKIRQNLKEKHARHIADLRAYYESE----------INSLKQKLEA------K 476
SLE+ + + + E + R + DL SE + L++K EA +
Sbjct: 356 SLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKER 415
Query: 477 EISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSA 536
I + K TN+ L RC Q+ T T +N EI + RE F
Sbjct: 416 LIEQRDTLKETNEEL--RCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHE 473
Query: 537 SKILQ--------ERIEEMRTSSKEKDNTIIRL-------KSRLQDLEEAFENAYKLSDD 581
+K+L+ ERIEE++ ++K + L K R+++L++ E+ K +
Sbjct: 474 NKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQE 533
Query: 582 KEAQLKQE--NKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLE 639
+ ++ + E +K+ Q L E L + H + L + + D I+ + I++LE
Sbjct: 534 QGSKSEGESSSKLKQKLEAHMEKLTEVH----EELQKKQELIEDLQPDINQNVQKINELE 589
Query: 640 AQVKQVEHENMLSLRHNSRIHVRPSRANTLATSD 673
A + Q + E+M ++ ++++ +R N + T D
Sbjct: 590 AAL-QKKDEDMKAMEERYKMYLEKAR-NVIKTLD 621
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 56.2 bits (134), Expect = 2e-07
Identities = 146/689 (21%), Positives = 278/689 (40%), Gaps = 100/689 (14%)
Query: 277 LTSASNPNHPPEVLTLDPTLH-MKPKQQIS--GIQPHGL-------PN--------ALD- 317
+T+ ++P PP + DP + P +++S I H PN +LD
Sbjct: 662 ITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDL 721
Query: 318 DRISFSPDS---------VLEPSMSSPSDI-DSFSQASNVTSQLPGFPKYPSHTKASPVD 367
D ++ SP+S V+E ++SSP+ I D S V S + +
Sbjct: 722 DSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTN 781
Query: 368 SWKNQTFQNESRTSSTFPSVYTITSND-ISVNTVDEENTVMVASASVSQSQLPGTANSVP 426
+ F + + + + + S+ T+ E+ + + Q + +NS
Sbjct: 782 VCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKED---LCHFRTFVQKEQCDFSNS-- 836
Query: 427 ECISLTSLEDPVILSKIRQNL----KEKHARHIADLRAYYESEINSLKQKLE-----AKE 477
+ T++E I+ K++ +L KEKH + + L+ YE +++ L ++ E K+
Sbjct: 837 --LKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKK 894
Query: 478 ISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNN--LLEIEVNDLRERFSAASS 535
+ G + ++L ++ + HE + V L+N+ + LLE+E N + +
Sbjct: 895 LKG--ELVCLEEVLQNKDNEFALVKHEKEA-VICLQNEKDQKLLEME-NIMHSQNCEIKE 950
Query: 536 ASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQE-NKMFQ 594
+ + +E+++ E D + L++ LQ LE++ + +L D + + QE K+
Sbjct: 951 LKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQS--HLKELEDTLQVRHIQEFEKVMT 1008
Query: 595 DLLGEYESLGKEHRRV--------KDALNTTENKLLDAYTQISDLKRMISKLEAQ--VKQ 644
D E L KE++++ + + E +L + ++SDL KLE + +K+
Sbjct: 1009 DHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKE 1068
Query: 645 VEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQ 704
E + + L SR + + + L + R + Q + + N
Sbjct: 1069 AETDEIKILLEESRAQQKETLKSLLEQETENLRTEISK-------LNQKIQDNNENYQVG 1121
Query: 705 LEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIFKNWGTQTE 764
L E +L +EKD S LI + E S+ I++A EL++ N + E
Sbjct: 1122 LAELRTL---MTIEKD-----QCISELISRHEEESN--ILKA--ELNKVTSLHNQAFEIE 1169
Query: 765 KEDTSNINPRQ----TETSVNASRSPEKCAQQRQK------RLNSASQRSSSLPPSNRKS 814
K I Q +E S + EK QQ +K L Q+ S +R+
Sbjct: 1170 KNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQ 1229
Query: 815 STP----TKREIMLTPVTVAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDTVP 870
K E + T + + ++ L HL ++ SP D D ++
Sbjct: 1230 LIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSP-AIDSTRGDSSSL- 1287
Query: 871 VSTLQRTNPRKQLQFLPLDDSEEKTYSEK 899
V+ LQ ++ +FL + +EK +E+
Sbjct: 1288 VAELQEKLQEEKAKFLEQLEEQEKRKNEE 1316
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 56.2 bits (134), Expect = 2e-07
Identities = 146/689 (21%), Positives = 278/689 (40%), Gaps = 100/689 (14%)
Query: 277 LTSASNPNHPPEVLTLDPTLH-MKPKQQIS--GIQPHGL-------PN--------ALD- 317
+T+ ++P PP + DP + P +++S I H PN +LD
Sbjct: 662 ITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDL 721
Query: 318 DRISFSPDS---------VLEPSMSSPSDI-DSFSQASNVTSQLPGFPKYPSHTKASPVD 367
D ++ SP+S V+E ++SSP+ I D S V S + +
Sbjct: 722 DSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTN 781
Query: 368 SWKNQTFQNESRTSSTFPSVYTITSND-ISVNTVDEENTVMVASASVSQSQLPGTANSVP 426
+ F + + + + + S+ T+ E+ + + Q + +NS
Sbjct: 782 VCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKED---LCHFRTFVQKEQCDFSNS-- 836
Query: 427 ECISLTSLEDPVILSKIRQNL----KEKHARHIADLRAYYESEINSLKQKLE-----AKE 477
+ T++E I+ K++ +L KEKH + + L+ YE +++ L ++ E K+
Sbjct: 837 --LKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKK 894
Query: 478 ISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNN--LLEIEVNDLRERFSAASS 535
+ G + ++L ++ + HE + V L+N+ + LLE+E N + +
Sbjct: 895 LKG--ELVCLEEVLQNKDNEFALVKHEKEA-VICLQNEKDQKLLEME-NIMHSQNCEIKE 950
Query: 536 ASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQE-NKMFQ 594
+ + +E+++ E D + L++ LQ LE++ + +L D + + QE K+
Sbjct: 951 LKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQS--HLKELEDTLQVRHIQEFEKVMT 1008
Query: 595 DLLGEYESLGKEHRRV--------KDALNTTENKLLDAYTQISDLKRMISKLEAQ--VKQ 644
D E L KE++++ + + E +L + ++SDL KLE + +K+
Sbjct: 1009 DHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKE 1068
Query: 645 VEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQ 704
E + + L SR + + + L + R + Q + + N
Sbjct: 1069 AETDEIKILLEESRAQQKETLKSLLEQETENLRTEISK-------LNQKIQDNNENYQVG 1121
Query: 705 LEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIFKNWGTQTE 764
L E +L +EKD S LI + E S+ I++A EL++ N + E
Sbjct: 1122 LAELRTL---MTIEKD-----QCISELISRHEEESN--ILKA--ELNKVTSLHNQAFEIE 1169
Query: 765 KEDTSNINPRQ----TETSVNASRSPEKCAQQRQK------RLNSASQRSSSLPPSNRKS 814
K I Q +E S + EK QQ +K L Q+ S +R+
Sbjct: 1170 KNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQ 1229
Query: 815 STP----TKREIMLTPVTVAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDTVP 870
K E + T + + ++ L HL ++ SP D D ++
Sbjct: 1230 LIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSP-AIDSTRGDSSSL- 1287
Query: 871 VSTLQRTNPRKQLQFLPLDDSEEKTYSEK 899
V+ LQ ++ +FL + +EK +E+
Sbjct: 1288 VAELQEKLQEEKAKFLEQLEEQEKRKNEE 1316
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 55.8 bits (133), Expect = 2e-07
Identities = 58/232 (25%), Positives = 112/232 (48%), Gaps = 27/232 (11%)
Query: 431 LTSLEDPVILSKIRQNLKEKHARHIADLRAY---YESEINSLKQKLEAKEISGVEDWKIT 487
LT L+ V K +H + I LR E +I++LK+ L +KE VE K+
Sbjct: 716 LTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE---VEVAKLE 772
Query: 488 NQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEM 547
Q+L ++ D+ + ++ E + LE EV+ L + + + + + ++
Sbjct: 773 KQLLEEKAAMTDAMVPRSS-----YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQI 827
Query: 548 RTS----SKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQ----ENKMFQDLLGE 599
R+ +EK+N LKS+ Q++ E + ++ + ++ A++K+ +K+ +D +
Sbjct: 828 RSEVSQVKREKENIQTLLKSKEQEVNELLQK-FQQAQEELAEMKRYAESSSKLEEDKDKK 886
Query: 600 YESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEA---QVKQVEHE 648
+ KE ++K+ALN+ L S KR +LEA QVKQ++++
Sbjct: 887 INEMSKEVTKLKEALNS----LSQLSYSTSSSKRQSQQLEALQQQVKQLQNQ 934
Score = 38.9 bits (89), Expect = 0.025
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 42/235 (17%)
Query: 402 EENTVMVASASVSQSQLPGTANSVPECIS-----LTSLEDPVILSKIRQNLKEKHAR--- 453
+EN+V + + L A + E IS L S E V ++K+ + L E+ A
Sbjct: 727 KENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE--VEVAKLEKQLLEEKAAMTD 784
Query: 454 ------HIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATS 507
L++ ESE++ L KL+ S E K+ ++++ R E +
Sbjct: 785 AMVPRSSYEKLQSSLESEVSVLASKLKE---SVKEKEKVHSEVVQIRS--------EVSQ 833
Query: 508 RVRTLENKNNLL---EIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSR 564
R EN LL E EVN+L ++F A ++ E ++KD I +
Sbjct: 834 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 893
Query: 565 LQDLEEAFEN----AYKLSDDKEAQ-----LKQENKMFQDLLGEYESLGKEHRRV 610
+ L+EA + +Y S K L+Q+ K Q+ L E + K+H+ V
Sbjct: 894 VTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK---KQHQEV 945
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 55.8 bits (133), Expect = 2e-07
Identities = 58/232 (25%), Positives = 112/232 (48%), Gaps = 27/232 (11%)
Query: 431 LTSLEDPVILSKIRQNLKEKHARHIADLRAY---YESEINSLKQKLEAKEISGVEDWKIT 487
LT L+ V K +H + I LR E +I++LK+ L +KE VE K+
Sbjct: 705 LTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE---VEVAKLE 761
Query: 488 NQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEM 547
Q+L ++ D+ + ++ E + LE EV+ L + + + + + ++
Sbjct: 762 KQLLEEKAAMTDAMVPRSS-----YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQI 816
Query: 548 RTS----SKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQ----ENKMFQDLLGE 599
R+ +EK+N LKS+ Q++ E + ++ + ++ A++K+ +K+ +D +
Sbjct: 817 RSEVSQVKREKENIQTLLKSKEQEVNELLQK-FQQAQEELAEMKRYAESSSKLEEDKDKK 875
Query: 600 YESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEA---QVKQVEHE 648
+ KE ++K+ALN+ L S KR +LEA QVKQ++++
Sbjct: 876 INEMSKEVTKLKEALNS----LSQLSYSTSSSKRQSQQLEALQQQVKQLQNQ 923
Score = 38.9 bits (89), Expect = 0.025
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 42/235 (17%)
Query: 402 EENTVMVASASVSQSQLPGTANSVPECIS-----LTSLEDPVILSKIRQNLKEKHAR--- 453
+EN+V + + L A + E IS L S E V ++K+ + L E+ A
Sbjct: 716 KENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE--VEVAKLEKQLLEEKAAMTD 773
Query: 454 ------HIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATS 507
L++ ESE++ L KL+ S E K+ ++++ R E +
Sbjct: 774 AMVPRSSYEKLQSSLESEVSVLASKLKE---SVKEKEKVHSEVVQIRS--------EVSQ 822
Query: 508 RVRTLENKNNLL---EIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSR 564
R EN LL E EVN+L ++F A ++ E ++KD I +
Sbjct: 823 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 882
Query: 565 LQDLEEAFEN----AYKLSDDKEAQ-----LKQENKMFQDLLGEYESLGKEHRRV 610
+ L+EA + +Y S K L+Q+ K Q+ L E + K+H+ V
Sbjct: 883 VTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK---KQHQEV 934
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 55.8 bits (133), Expect = 2e-07
Identities = 58/232 (25%), Positives = 112/232 (48%), Gaps = 27/232 (11%)
Query: 431 LTSLEDPVILSKIRQNLKEKHARHIADLRAY---YESEINSLKQKLEAKEISGVEDWKIT 487
LT L+ V K +H + I LR E +I++LK+ L +KE VE K+
Sbjct: 684 LTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE---VEVAKLE 740
Query: 488 NQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEM 547
Q+L ++ D+ + ++ E + LE EV+ L + + + + + ++
Sbjct: 741 KQLLEEKAAMTDAMVPRSS-----YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQI 795
Query: 548 RTS----SKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQ----ENKMFQDLLGE 599
R+ +EK+N LKS+ Q++ E + ++ + ++ A++K+ +K+ +D +
Sbjct: 796 RSEVSQVKREKENIQTLLKSKEQEVNELLQK-FQQAQEELAEMKRYAESSSKLEEDKDKK 854
Query: 600 YESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEA---QVKQVEHE 648
+ KE ++K+ALN+ L S KR +LEA QVKQ++++
Sbjct: 855 INEMSKEVTKLKEALNS----LSQLSYSTSSSKRQSQQLEALQQQVKQLQNQ 902
Score = 38.9 bits (89), Expect = 0.025
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 42/235 (17%)
Query: 402 EENTVMVASASVSQSQLPGTANSVPECIS-----LTSLEDPVILSKIRQNLKEKHAR--- 453
+EN+V + + L A + E IS L S E V ++K+ + L E+ A
Sbjct: 695 KENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE--VEVAKLEKQLLEEKAAMTD 752
Query: 454 ------HIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATS 507
L++ ESE++ L KL+ S E K+ ++++ R E +
Sbjct: 753 AMVPRSSYEKLQSSLESEVSVLASKLKE---SVKEKEKVHSEVVQIRS--------EVSQ 801
Query: 508 RVRTLENKNNLL---EIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSR 564
R EN LL E EVN+L ++F A ++ E ++KD I +
Sbjct: 802 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 861
Query: 565 LQDLEEAFEN----AYKLSDDKEAQ-----LKQENKMFQDLLGEYESLGKEHRRV 610
+ L+EA + +Y S K L+Q+ K Q+ L E + K+H+ V
Sbjct: 862 VTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK---KQHQEV 913
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 55.8 bits (133), Expect = 2e-07
Identities = 58/232 (25%), Positives = 112/232 (48%), Gaps = 27/232 (11%)
Query: 431 LTSLEDPVILSKIRQNLKEKHARHIADLRAY---YESEINSLKQKLEAKEISGVEDWKIT 487
LT L+ V K +H + I LR E +I++LK+ L +KE VE K+
Sbjct: 713 LTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE---VEVAKLE 769
Query: 488 NQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEM 547
Q+L ++ D+ + ++ E + LE EV+ L + + + + + ++
Sbjct: 770 KQLLEEKAAMTDAMVPRSS-----YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQI 824
Query: 548 RTS----SKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQ----ENKMFQDLLGE 599
R+ +EK+N LKS+ Q++ E + ++ + ++ A++K+ +K+ +D +
Sbjct: 825 RSEVSQVKREKENIQTLLKSKEQEVNELLQK-FQQAQEELAEMKRYAESSSKLEEDKDKK 883
Query: 600 YESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEA---QVKQVEHE 648
+ KE ++K+ALN+ L S KR +LEA QVKQ++++
Sbjct: 884 INEMSKEVTKLKEALNS----LSQLSYSTSSSKRQSQQLEALQQQVKQLQNQ 931
Score = 38.9 bits (89), Expect = 0.025
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 42/235 (17%)
Query: 402 EENTVMVASASVSQSQLPGTANSVPECIS-----LTSLEDPVILSKIRQNLKEKHAR--- 453
+EN+V + + L A + E IS L S E V ++K+ + L E+ A
Sbjct: 724 KENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE--VEVAKLEKQLLEEKAAMTD 781
Query: 454 ------HIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATS 507
L++ ESE++ L KL+ S E K+ ++++ R E +
Sbjct: 782 AMVPRSSYEKLQSSLESEVSVLASKLKE---SVKEKEKVHSEVVQIRS--------EVSQ 830
Query: 508 RVRTLENKNNLL---EIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSR 564
R EN LL E EVN+L ++F A ++ E ++KD I +
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 890
Query: 565 LQDLEEAFEN----AYKLSDDKEAQ-----LKQENKMFQDLLGEYESLGKEHRRV 610
+ L+EA + +Y S K L+Q+ K Q+ L E + K+H+ V
Sbjct: 891 VTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK---KQHQEV 942
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 55.8 bits (133), Expect = 2e-07
Identities = 58/232 (25%), Positives = 112/232 (48%), Gaps = 27/232 (11%)
Query: 431 LTSLEDPVILSKIRQNLKEKHARHIADLRAY---YESEINSLKQKLEAKEISGVEDWKIT 487
LT L+ V K +H + I LR E +I++LK+ L +KE VE K+
Sbjct: 713 LTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE---VEVAKLE 769
Query: 488 NQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEM 547
Q+L ++ D+ + ++ E + LE EV+ L + + + + + ++
Sbjct: 770 KQLLEEKAAMTDAMVPRSS-----YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQI 824
Query: 548 RTS----SKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQ----ENKMFQDLLGE 599
R+ +EK+N LKS+ Q++ E + ++ + ++ A++K+ +K+ +D +
Sbjct: 825 RSEVSQVKREKENIQTLLKSKEQEVNELLQK-FQQAQEELAEMKRYAESSSKLEEDKDKK 883
Query: 600 YESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEA---QVKQVEHE 648
+ KE ++K+ALN+ L S KR +LEA QVKQ++++
Sbjct: 884 INEMSKEVTKLKEALNS----LSQLSYSTSSSKRQSQQLEALQQQVKQLQNQ 931
Score = 38.9 bits (89), Expect = 0.025
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 42/235 (17%)
Query: 402 EENTVMVASASVSQSQLPGTANSVPECIS-----LTSLEDPVILSKIRQNLKEKHAR--- 453
+EN+V + + L A + E IS L S E V ++K+ + L E+ A
Sbjct: 724 KENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE--VEVAKLEKQLLEEKAAMTD 781
Query: 454 ------HIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATS 507
L++ ESE++ L KL+ S E K+ ++++ R E +
Sbjct: 782 AMVPRSSYEKLQSSLESEVSVLASKLKE---SVKEKEKVHSEVVQIRS--------EVSQ 830
Query: 508 RVRTLENKNNLL---EIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSR 564
R EN LL E EVN+L ++F A ++ E ++KD I +
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 890
Query: 565 LQDLEEAFEN----AYKLSDDKEAQ-----LKQENKMFQDLLGEYESLGKEHRRV 610
+ L+EA + +Y S K L+Q+ K Q+ L E + K+H+ V
Sbjct: 891 VTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK---KQHQEV 942
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 55.8 bits (133), Expect = 2e-07
Identities = 58/232 (25%), Positives = 112/232 (48%), Gaps = 27/232 (11%)
Query: 431 LTSLEDPVILSKIRQNLKEKHARHIADLRAY---YESEINSLKQKLEAKEISGVEDWKIT 487
LT L+ V K +H + I LR E +I++LK+ L +KE VE K+
Sbjct: 713 LTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE---VEVAKLE 769
Query: 488 NQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEM 547
Q+L ++ D+ + ++ E + LE EV+ L + + + + + ++
Sbjct: 770 KQLLEEKAAMTDAMVPRSS-----YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQI 824
Query: 548 RTS----SKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQ----ENKMFQDLLGE 599
R+ +EK+N LKS+ Q++ E + ++ + ++ A++K+ +K+ +D +
Sbjct: 825 RSEVSQVKREKENIQTLLKSKEQEVNELLQK-FQQAQEELAEMKRYAESSSKLEEDKDKK 883
Query: 600 YESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEA---QVKQVEHE 648
+ KE ++K+ALN+ L S KR +LEA QVKQ++++
Sbjct: 884 INEMSKEVTKLKEALNS----LSQLSYSTSSSKRQSQQLEALQQQVKQLQNQ 931
Score = 38.9 bits (89), Expect = 0.025
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 42/235 (17%)
Query: 402 EENTVMVASASVSQSQLPGTANSVPECIS-----LTSLEDPVILSKIRQNLKEKHAR--- 453
+EN+V + + L A + E IS L S E V ++K+ + L E+ A
Sbjct: 724 KENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE--VEVAKLEKQLLEEKAAMTD 781
Query: 454 ------HIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATS 507
L++ ESE++ L KL+ S E K+ ++++ R E +
Sbjct: 782 AMVPRSSYEKLQSSLESEVSVLASKLKE---SVKEKEKVHSEVVQIRS--------EVSQ 830
Query: 508 RVRTLENKNNLL---EIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSR 564
R EN LL E EVN+L ++F A ++ E ++KD I +
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 890
Query: 565 LQDLEEAFEN----AYKLSDDKEAQ-----LKQENKMFQDLLGEYESLGKEHRRV 610
+ L+EA + +Y S K L+Q+ K Q+ L E + K+H+ V
Sbjct: 891 VTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK---KQHQEV 942
>gi|157785668 coiled-coil domain containing 39 [Homo sapiens]
Length = 941
Score = 55.5 bits (132), Expect = 3e-07
Identities = 114/628 (18%), Positives = 251/628 (39%), Gaps = 108/628 (17%)
Query: 441 SKIRQNLKEKHARHIADLR------AYYESEINSLKQKLEAKEISGVEDWKITN-QILVD 493
S+I N + + +AD + AY + E + ++ K E + + ++ + L
Sbjct: 271 SEIGNNTEFEKRISVADRKLLKCRTAYQDHETSRIQLKGELDSLKATVNRTSSDLEALRK 330
Query: 494 RCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKE 553
++ +HE T+R++ +N N +++ ++ ++ E+ + + L++ ++E KE
Sbjct: 331 NISKIKKDIHEETARLQKTKNHNEIIQTKLKEITEKTMSVEEKATNLEDMLKEEEKDVKE 390
Query: 554 KDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDA 613
D + +K L +K + + + + +E + ++ G SL + +++
Sbjct: 391 VDVQLNLIKGVL----------FKKAQELQTETMKEKAVLSEIEGTRSSLKHLNHQLQKL 440
Query: 614 LNTTENKLLDAYTQ---ISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANTLA 670
T + Y+Q I ++R +S+L+ ++ E + L
Sbjct: 441 DFETLKQQEIMYSQDFHIQQVERRMSRLKGEINSEEKQ-------------------ALE 481
Query: 671 TSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSL 730
V RK L E T L+TQ + N L ++K S S
Sbjct: 482 AKIVELRKSL----EEKKSTCGLLETQIKKLHNDLYF---------IKKAHSKNSDEKQS 528
Query: 731 LIKKQRETSDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCA 790
L+ K E + I R+ KELD+ K FK +++ + ++T +++
Sbjct: 529 LMTKINELN-LFIDRSEKELDKAKGFKQ--DLMIEDNLLKLEVKRTREMLHSKAEEVLSL 585
Query: 791 QQRQKRLNSASQRSSSLPPSNRKSSTPTKREIMLTPVTVAYSPKRSPKENLSPGFSHLLS 850
++R+++L +A + R + ++ + + +EN+S F LS
Sbjct: 586 EKRKQQLYTAMEE--------RTEEIKVHKTMLASQIRYV----DQERENISTEFRERLS 633
Query: 851 KNESSPIRFDILL--------DDLDTVPVSTLQRTNPRKQLQ------FLPLDDSEEKTY 896
K E R++IL ++ T ++ +++LQ ++ +E++ Y
Sbjct: 634 KIEKLKNRYEILTVVMLPPEGEEEKTQAYYVIKAAQEKEELQREGDCLDAKINKAEKEIY 693
Query: 897 SEKATDNHVNHSSCPEPVPNGVKKVS-------VRTAWEKNK-----SVSYEQCKPVSVT 944
+ + T +N SC KKV+ ++ E+ K Y+Q + +
Sbjct: 694 ALENTLQVLN--SCNNNYKQSFKKVTPSSDEYELKIQLEEQKRAVDEKYRYKQRQIRELQ 751
Query: 945 PQGNDFEYTAKI---------RTLAETERFFDELTKEKDQIEAALSRMPSPGGRITLQTR 995
E T + L+E + + +L+KE ++ + L R+ ++T + R
Sbjct: 752 EDIQSMENTLDVIEHLANNVKEKLSEKQAYSFQLSKETEEQKPKLERVTKQCAKLTKEIR 811
Query: 996 LNQEALEDRLERINRELGSVRMTLKKFH 1023
L ++ ++ +E + +L +K+FH
Sbjct: 812 LLKDTKDETMEEQDIKL----REMKQFH 835
Score = 32.0 bits (71), Expect = 3.1
Identities = 32/159 (20%), Positives = 62/159 (38%), Gaps = 3/159 (1%)
Query: 488 NQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEM 547
N++L D+ +L +R E + N + ++++ S S K + E
Sbjct: 24 NKLLEDQLSKLKDERASLQDELREYEERINSMTSHFKNVKQELSITQSLCKARERETESE 83
Query: 548 RTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEH 607
+ R+K +Q LE + + DKE + K Q L G + +
Sbjct: 84 EHFKAIAQRELGRVKDEIQRLENEMASILEKKSDKENGI---FKATQKLDGLKCQMNWDQ 140
Query: 608 RRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVE 646
+ ++ L + +K DA T ++ +K+ A Q+E
Sbjct: 141 QALEAWLEESAHKDSDALTLQKYAQQDDNKIRALTLQLE 179
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 54.3 bits (129), Expect = 6e-07
Identities = 84/355 (23%), Positives = 145/355 (40%), Gaps = 60/355 (16%)
Query: 359 SHTKAS---PVDSWKNQTFQNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQ 415
SHTK PV + + N S T T N++ + T A +
Sbjct: 1274 SHTKLQEEIPVLHEEQELLPNVKEVSETQE-----TMNELELLTEQSTTKDSTTLARIEM 1328
Query: 416 SQL---PGTANSVPECISLTSLEDPVILSKIRQNLKEKHAR---HIADLRAYYESEINSL 469
+L S E SLT D L I++ L+ KH + HI + A + +
Sbjct: 1329 ERLRLNEKFQESQEEIKSLTKERDN--LKTIKEALEVKHDQLKEHIRETLAKIQESQSKQ 1386
Query: 470 KQKLEAKE--------ISGVEDWKITNQIL----VDRCGQLDSALHEATSRVRTLEN--- 514
+Q L KE +S +E +K + L ++ G L L E+ ++++
Sbjct: 1387 EQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLG-LSKRLQESHDEMKSVAKEKD 1445
Query: 515 ----------------KNNLLEIEVNDLR--ERFSAASSASKILQERIEEMRTSSKEKDN 556
K N+ EI L E A K +E I E+R + EK+
Sbjct: 1446 DLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKET 1505
Query: 557 TIIRLKSRLQDLEEAFENAYKLSDDKEAQ--LKQENKMFQDLLGEYESLGKEHRRVKD-A 613
I ++ +L+ + + +N + +KE Q +KQ +++ Q+ + E + KEHR+ KD A
Sbjct: 1506 EISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEV-QEKVNELKQF-KEHRKAKDSA 1563
Query: 614 LNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANT 668
L + E+K+L+ ++ + S+ E Q+ E E M ++ +I + NT
Sbjct: 1564 LQSIESKMLELTNRLQE-----SQEEIQIMIKEKEEMKRVQEALQIERDQLKENT 1613
Score = 42.4 bits (98), Expect = 0.002
Identities = 69/330 (20%), Positives = 134/330 (40%), Gaps = 45/330 (13%)
Query: 427 ECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKE--------- 477
E ++L + + L LKEK + +A E++I + +LEAK+
Sbjct: 631 ETVALDAKRESAFLRSENLELKEK-MKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKE 689
Query: 478 ----------ISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLR 527
++ + D K+ +L + +L+ + + + +N L EV L
Sbjct: 690 LQSAFNEITKLTSLIDGKVPKDLLCNL--ELEGKITDLQKELNKEVEENEALREEVILLS 747
Query: 528 ERFSAASSASKI---LQERIEEMRTSSKEKD---NTIIRLKSRLQDLEEAFENAYKLSDD 581
E S S ++ +Q++ EE+ + EKD + ++ +SR+Q L E K DD
Sbjct: 748 ELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGL---LEEIGKTKDD 804
Query: 582 ---KEAQLKQENKMFQ-------DLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDL 631
++ K ++ FQ D +Y+ + +E+ R+ + + + + L
Sbjct: 805 LATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGAL 864
Query: 632 KRMISKLEAQVKQVEHENMLSLRHNSRIHVR-PSRANTLATSDVSRRKWLIPGAEYSIFT 690
K +S ++++ E L ++ + +R +TL T V R K LI
Sbjct: 865 KTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQT--VEREKTLITEKLQQTLE 922
Query: 691 GQPLDTQDSNVDNQLEETCSLGHRSPLEKD 720
TQ+ + QL+E+ + R L+ D
Sbjct: 923 EVKTLTQEKDDLKQLQESLQI-ERDQLKSD 951
Score = 42.4 bits (98), Expect = 0.002
Identities = 48/232 (20%), Positives = 109/232 (46%), Gaps = 33/232 (14%)
Query: 431 LTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQI 490
+ S E + K+R+ + EK + I+D++ + + L++K++ + ++ ++ +
Sbjct: 1931 MLSKEHKETVDKLREKISEKTIQ-ISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDV 1989
Query: 491 LVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLR-ERFSAASSASKILQERIEEMRT 549
+ H+ + + L+ + + + +R + F +K L E +EE+R
Sbjct: 1990 NMS---------HKKINEMEQLKKQFEAQNLSMQSVRMDNFQL----TKKLHESLEEIRI 2036
Query: 550 SSKEKDNTIIRLKSRLQDLEEAFENAYK---LSDDKEAQLKQENKMFQDLLGEY---ESL 603
+KE+D + R+K L+ + F + D + Q+K E ++ D G+ ESL
Sbjct: 2037 VAKERDE-LRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSD--GQQHLTESL 2093
Query: 604 GKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQV-KQVEHENMLSLR 654
++ R+K+ LL Y+++ D +++L + K++E + LS+R
Sbjct: 2094 REKCSRIKE--------LLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMR 2137
Score = 40.4 bits (93), Expect = 0.009
Identities = 54/235 (22%), Positives = 105/235 (44%), Gaps = 46/235 (19%)
Query: 443 IRQNLKEKHA--RHIADLRAYYES---EINSLKQKLE---AKEISGVEDWKITNQIL--- 491
+ +NL+E + + DLR+ E+ E + LK+ L +++ E+ KI + L
Sbjct: 1674 LHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEH 1733
Query: 492 ---VDRC-GQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEM 547
+D+ G + +E ++ + LE+ N+ L+ + ++E A K QE I+++
Sbjct: 1734 QETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKL 1793
Query: 548 RTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEH 607
R EK + +L ++++ EN+ +K +LK EH
Sbjct: 1794 RGIVSEKTD-------KLSNMQKDLENSNAKLQEKIQELK----------------ANEH 1830
Query: 608 RRV--KDALNTTENKLLD---AYTQISDLKRMISKLEAQ---VKQVEHENMLSLR 654
+ + K +N T+ K+ + QI D +SKLE + + Q HEN+ ++
Sbjct: 1831 QLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMK 1885
Score = 37.0 bits (84), Expect = 0.096
Identities = 104/547 (19%), Positives = 216/547 (39%), Gaps = 79/547 (14%)
Query: 462 YESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEI 521
++S + +LK +L K Q L ++ ++ L+E LEN+++ L+
Sbjct: 857 FDSSLGALKTELSYK-----------TQELQEKTREVQERLNEMEQLKEQLENRDSTLQT 905
Query: 522 EVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFE-NAYKLSD 580
+ + ++ LQ+ +EE++T ++EKD+ L+ L+E+ + +L
Sbjct: 906 VERE-------KTLITEKLQQTLEEVKTLTQEKDD--------LKQLQESLQIERDQLKS 950
Query: 581 DKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEA 640
D + + L ESL K+H ++ +NT ++K+ + ++ ++ + +
Sbjct: 951 DIHDTVNMNIDTQEQLRNALESL-KQH---QETINTLKSKISEEVSRNLHMEENTGETKD 1006
Query: 641 QVKQVEHENMLSLRHNSRIHVRPSRANTLATSD-------------VSRRKWLIPGAEYS 687
+ +Q M+ + + + ++ T D + + L E
Sbjct: 1007 EFQQ----KMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESV 1062
Query: 688 IFTGQPLDTQ-----DSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTP 742
I + L T + ++NQ EE LG L+K + + IKK+ E S T
Sbjct: 1063 IAEKEQLKTDLKENIEMTIENQ-EELRLLG--DELKKQQEIVAQEKNHAIKKEGELSRT- 1118
Query: 743 IMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQ 802
L E++E K+ Q +++ N+ +E + + + K L
Sbjct: 1119 -CDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHM 1177
Query: 803 RSSSLPPSNR------KSSTPTKREIMLTPVTVAYSPKRSP-----KENLSPGFSHLLSK 851
+ L + + + + TK +L + ++ +R +E + G L
Sbjct: 1178 ETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATG----LQT 1233
Query: 852 NESSPIRFDILLDDLDTVPVSTLQRTNPRKQLQFLPLDDSEEKTYSEKATDNHVNHSSCP 911
E I L + +T + L+R+ K Q + D EK++++ + V H
Sbjct: 1234 KEELKIAHIHLKEHQET--IDELRRSVSEKTAQIINTQDL-EKSHTKLQEEIPVLHEE-Q 1289
Query: 912 EPVPNGVKKVS-VRTAWEKNKSVSYEQCKPVSVTPQGNDFEYTAKIRTLAETERFFDELT 970
E +PN VK+VS + + + ++ + S T + E E++ LT
Sbjct: 1290 ELLPN-VKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLT 1348
Query: 971 KEKDQIE 977
KE+D ++
Sbjct: 1349 KERDNLK 1355
Score = 35.0 bits (79), Expect = 0.36
Identities = 64/349 (18%), Positives = 130/349 (37%), Gaps = 41/349 (11%)
Query: 500 SALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDN--- 556
+A++E ++ +E+ E + +L + ++IL E +EEMR+ +KE+D+
Sbjct: 1634 TAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRS 1693
Query: 557 ------------------TIIR-------LKSRLQDLEEAFENAYKLSDDKEAQLKQENK 591
TI R LK L+E E KL + + +
Sbjct: 1694 VEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISN 1753
Query: 592 MFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMIS----KLEAQVKQVEH 647
M +DL ++L + ++++ L L + I L+ ++S KL K +E+
Sbjct: 1754 MQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLEN 1813
Query: 648 EN------MLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNV 701
N + L+ N + + VS + L + T L+ ++ N+
Sbjct: 1814 SNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNL 1873
Query: 702 DNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIFKNWGT 761
+L E E+D+ T L + Q + S E+ + +
Sbjct: 1874 AQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLS 1933
Query: 762 QTEKEDTSNINPRQTETSVNAS---RSPEKCAQQRQKRLNSASQRSSSL 807
+ KE + + +E ++ S + +K + QK++ ++ L
Sbjct: 1934 KEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQL 1982
Score = 32.7 bits (73), Expect = 1.8
Identities = 46/195 (23%), Positives = 83/195 (42%), Gaps = 23/195 (11%)
Query: 508 RVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQD 567
++RT + + L E NDL E F A +K QE ++ N + + QD
Sbjct: 516 QLRTEKEEMELKLKEKNDLDE-FEALERKTKKDQEM--QLIHEISNLKNLVKHAEVYNQD 572
Query: 568 LEEAFENAYKLSDDKEAQLKQENKMF---------QDLLGEYESLGKEHRRVKDALNTTE 618
LE + +L +KE Q+K+ + DL ES+ ++ +++K L E
Sbjct: 573 LENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESI-EDPKQMKQTLFDAE 631
Query: 619 NKLLDAYTQIS-------DLKRMISKLEAQVKQVEHENML---SLRHNSRIHVRPSRANT 668
LDA + + +LK + +L KQ+E++ L L ++ V +
Sbjct: 632 TVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQ 691
Query: 669 LATSDVSRRKWLIPG 683
A +++++ LI G
Sbjct: 692 SAFNEITKLTSLIDG 706
Score = 30.4 bits (67), Expect = 9.0
Identities = 48/247 (19%), Positives = 109/247 (44%), Gaps = 48/247 (19%)
Query: 440 LSKIRQNLKEKHAR---HIADLRAY------YESEINSLKQKLEAKEI--SGVEDWKITN 488
LS ++++L+ +A+ I +L+A + ++N ++K+ E ++D +T
Sbjct: 1804 LSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTL 1863
Query: 489 QILVDRCGQLDSALHEATSRVRT-LENKNNLLEIEVNDLRERFSAASSASKILQERIEE- 546
L L LHE +++ ++ ++NL +E ER L+E ++E
Sbjct: 1864 SKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQ--------LKESLQET 1915
Query: 547 -------------MRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMF 593
R SKE T+ +L+ ++ E ++SD ++ K ++++
Sbjct: 1916 KARDLEIQQELKTARMLSKEHKETVDKLREKIS------EKTIQISDIQKDLDKSKDEL- 1968
Query: 594 QDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSL 653
Q + E + + RVK+ +N + K I++++++ + EAQ ++ M +
Sbjct: 1969 QKKIQELQKKELQLLRVKEDVNMSHKK-------INEMEQLKKQFEAQNLSMQSVRMDNF 2021
Query: 654 RHNSRIH 660
+ ++H
Sbjct: 2022 QLTKKLH 2028
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 53.9 bits (128), Expect = 8e-07
Identities = 68/341 (19%), Positives = 145/341 (42%), Gaps = 19/341 (5%)
Query: 347 VTSQLP--GFPKYPSHTKASPVDSWKNQTFQNESRT--SSTFPSVYTITSNDISVNTVDE 402
V +QLP GF Y + S + N+T N ++ S ++Y + + + +
Sbjct: 388 VGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKD 447
Query: 403 ENTVMVASASVS----QSQLPGTANSVPECISLTS-LEDPVILSKIRQNLKEKHARHIAD 457
E ++++ +L N S S +E +L + R N ++ A +
Sbjct: 448 EMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENE 507
Query: 458 LRAYYESEINSLKQKLE-AKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKN 516
R E+E+++LK +LE K++S +Q+ ++ QL L EA +RT +
Sbjct: 508 KRRNVENEVSTLKDQLEDLKKVSQ------NSQLANEKLSQLQKQLEEANDLLRTESDTA 561
Query: 517 NLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAY 576
L ++ + S S ++ LQER + S + D +L++ L+ +
Sbjct: 562 VRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDS 621
Query: 577 KLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMIS 636
++ D +A++ + + L E + E + +D LN +E + + DL +
Sbjct: 622 EMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEI---DLNYKLK 678
Query: 637 KLEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRR 677
L+ +++Q +E+ ++ + H A ++A ++ ++
Sbjct: 679 SLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKK 719
Score = 39.3 bits (90), Expect = 0.019
Identities = 49/225 (21%), Positives = 93/225 (41%), Gaps = 20/225 (8%)
Query: 441 SKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITN-----QILVDRC 495
++I +N K + + L+A E+E + + E+ G +IT+ + L
Sbjct: 589 NRILENSKSQTDKDYYQLQAILEAE---RRDRGHDSEMIGDLQARITSLQEEVKHLKHNL 645
Query: 496 GQLDSALHEATSRVRTLENKNNLLEIEVN----DLRERFSAASSASKILQERIEEMRTSS 551
+++ EA + E + N LEI++N L++R + K+ + R+ + S
Sbjct: 646 EKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSI 705
Query: 552 KE-KDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQ-------LKQENKMFQDLLGEYESL 603
+E K + ++ +L++ EA E A E Q LKQ + + L G E +
Sbjct: 706 EEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERM 765
Query: 604 GKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHE 648
E + + L NK L ++ L+ KQ++ E
Sbjct: 766 EDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQE 810
Score = 38.1 bits (87), Expect = 0.043
Identities = 42/213 (19%), Positives = 93/213 (43%), Gaps = 39/213 (18%)
Query: 390 ITSNDISVNTVDEENTVMVASASVSQSQLPGTANSVPECISLTSLEDPVILSKIRQNLKE 449
IT D +V+ ++E N+++ + + + + K + K
Sbjct: 931 ITDKDHTVSRLEEANSMLTKDIEILRRENEELTEK---------------MKKAEEEYKL 975
Query: 450 KHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRV 509
+ I++L+A +E IN+ ++ L+ + ++ + + +DR T +
Sbjct: 976 EKEEEISNLKAAFEKNINT-ERTLKTQAVNKLAEIMNRKDFKIDR-------KKANTQDL 1027
Query: 510 RTLENKNNLLEIEVNDLRERFSA-----ASSASKILQERIEE--------MRTSSKEKDN 556
R E +N L++E+N RE+F+ + + + +EE M+ +SKE D
Sbjct: 1028 RKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESD- 1086
Query: 557 TIIRLKSRLQDLEEAFENA-YKLSDDKEAQLKQ 588
I +L+++L DL ++ A + +D+ + L +
Sbjct: 1087 -IEQLRAKLLDLSDSTSVASFPSADETDGNLPE 1118
Score = 33.5 bits (75), Expect = 1.1
Identities = 68/375 (18%), Positives = 139/375 (37%), Gaps = 60/375 (16%)
Query: 449 EKHARHIADLRAYYESEINSLKQKLEAKEISGV--EDWKITNQILVDRCGQLDSALHEAT 506
++ H+ + E E+ +L +LE + + ++ T D L+ + +
Sbjct: 752 QQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQ-- 809
Query: 507 SRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQ 566
+ TL LLE E+ L +++ + LQ+++E
Sbjct: 810 -EINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLE--------------------- 847
Query: 567 DLEEAFENAYK-----LSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKL 621
E+ F YK L ++ E + ++ K Q+L E E+L + L+ E K
Sbjct: 848 -AEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQ-------LDLAETKA 899
Query: 622 LDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLI 681
L+ +L + K+ N + R AN++ T D+ I
Sbjct: 900 ESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIE-----I 954
Query: 682 PGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKK------- 734
E T + ++ + EE +L ++ EK+ + + + + K
Sbjct: 955 LRRENEELTEKMKKAEEEYKLEKEEEISNL--KAAFEKNINTERTLKTQAVNKLAEIMNR 1012
Query: 735 -----QRETSDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKC 789
R+ ++T +R KE + K+ + EK + + Q E + ++ E+C
Sbjct: 1013 KDFKIDRKKANTQDLRK-KEKENRKLQLELNQEREKFNQMVVK-HQKELNDMQAQLVEEC 1070
Query: 790 AQQRQKRLNSASQRS 804
A + + ++ AS+ S
Sbjct: 1071 AHRNELQMQLASKES 1085
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 53.5 bits (127), Expect = 1e-06
Identities = 64/258 (24%), Positives = 120/258 (46%), Gaps = 35/258 (13%)
Query: 396 SVNTVDEENTVMV-ASASVSQSQLPGTANSVPECISLTSLEDP--VILSKIRQNLKEKHA 452
S++TV++ +V AS S + +L A I L LE +L ++ ++ + +
Sbjct: 564 SLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELE 623
Query: 453 RHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTL 512
R L +E E++ LK+ LE + +E K+ + + + Q+D +E + ++ T+
Sbjct: 624 RLRTQLLFSHEEELSKLKEDLEIEHRINIE--KLKDNLGIHYKQQIDGLQNEMSQKIETM 681
Query: 513 E-------NKNNLLEIEVNDLRE-RFSAASSASKI-------LQERIEEMRTSSKEKDNT 557
+ K N L +E++ L++ + S +S S+ LQ+ IE +R KEK
Sbjct: 682 QFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGT- 740
Query: 558 IIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTT 617
L+ +Q+L+ E K +KE DL ++ L E+ +KD T
Sbjct: 741 ---LEQEVQELQLKTELLEKQMKEKE----------NDLQEKFAQLEAENSILKDEKKTL 787
Query: 618 ENKLLDAYTQISDLKRMI 635
E+ +L +T +S +R+I
Sbjct: 788 ED-MLKIHTPVSQEERLI 804
Score = 44.3 bits (103), Expect = 6e-04
Identities = 47/220 (21%), Positives = 94/220 (42%), Gaps = 32/220 (14%)
Query: 445 QNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQI--LVDRCGQLDSAL 502
Q + E R + L + + + + + L +KE + + +I L R +L+ AL
Sbjct: 2101 QPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQAL 2160
Query: 503 HEATSRVRTLENKNNL----------LEIEVNDLRERFSAASSASKILQERIEEMRTSSK 552
+ + +E++ + LE+++ R+ L+E++E+ R +
Sbjct: 2161 LVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELE 2220
Query: 553 EKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKD 612
K+ + Q L E K S + +L+QENK+F+D + E LG + D
Sbjct: 2221 NKNEEV-------QQLHMQLEIQKKESTTRLQELEQENKLFKD---DMEKLGLAIKE-SD 2269
Query: 613 ALNTTENKLL---------DAYTQISDLKRMISKLEAQVK 643
A++T + +L + +I L ++KL+ Q+K
Sbjct: 2270 AMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLK 2309
Score = 42.0 bits (97), Expect = 0.003
Identities = 75/410 (18%), Positives = 170/410 (41%), Gaps = 35/410 (8%)
Query: 402 EENTVMVASASVSQSQLPGTANSVP--ECISLTSLEDPVILSKIRQNLKEKHARHIADLR 459
EE +V++A+ + L GT ++V C+ E V + L++ R +
Sbjct: 3036 EERSVLLAAFRTELTAL-GTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEI 3094
Query: 460 AYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLL 519
+++N K L+ ++ E K + ++L Q S + E + +++++ L
Sbjct: 3095 QALHAQMNGRKITLKREQ----ESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATEL 3150
Query: 520 EIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLS 579
+ +++ E+ A S++ Q ++E + T+ K + + L++ ++++ + + L+
Sbjct: 3151 QEQLSS--EKMVVAELKSELAQTKLE-LETTLKAQHKHLKELEAFRLEVKDKTDEVHLLN 3207
Query: 580 DDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISK-- 637
D ++ K+ ++ L E LG+ R K+ L + L + L ++ +
Sbjct: 3208 DTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQK 3267
Query: 638 --LEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLD 695
L +++E + ML S R L S+ R + + LD
Sbjct: 3268 QLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREM----------SSTLD 3317
Query: 696 TQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLL--IKKQRETSDTPIMRALKELDEG 753
++ + QL+ + G S P S LL ++KQ E + I+ L E ++
Sbjct: 3318 -RERELHAQLQSSDGTG-------QSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKY 3369
Query: 754 KIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQR 803
K+ + T+ + E ++ + +T A+ +K + Q ++ ++
Sbjct: 3370 KL-DSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQ 3418
Score = 34.3 bits (77), Expect = 0.62
Identities = 46/227 (20%), Positives = 96/227 (42%), Gaps = 12/227 (5%)
Query: 424 SVPECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVED 483
++ E ++++ + V+ K Q ++EK I L ++ L+Q+L+ + V +
Sbjct: 2264 AIKESDAMSTQDQHVLFGKFAQIIQEKEVE-IDQLN----EQVTKLQQQLKITTDNKVIE 2318
Query: 484 WKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQER 543
K N+++ D Q++ + + R E + L + L++ + + +
Sbjct: 2319 EK--NELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHS 2376
Query: 544 IEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESL 603
+ E S K + + +I K L E+ E A + + LK+ N L E SL
Sbjct: 2377 LSEEADSLKHQLDVVIAEKLAL---EQQVETANEEMTFMKNVLKETNFKMNQLTQELFSL 2433
Query: 604 GKEHRRVKDALNTTENKLLDAYTQISDLKRMISKL--EAQVKQVEHE 648
+E V+ + EN + A +S K + + E +K +E++
Sbjct: 2434 KRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQ 2480
Score = 30.4 bits (67), Expect = 9.0
Identities = 66/322 (20%), Positives = 125/322 (38%), Gaps = 44/322 (13%)
Query: 375 QNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQSQLPGTANSVPEC---ISL 431
+ ES S Y I + + E + M A+ Q QL V E ++
Sbjct: 3111 EQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQ 3170
Query: 432 TSLEDPVILSKIRQNLKEKHARHIADLRAYY------ESEINSLKQKLEAKEISGVE-DW 484
T LE + LK +H +H+ +L A+ E++ L L +++ E W
Sbjct: 3171 TKLE-------LETTLKAQH-KHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQW 3222
Query: 485 KITNQILVDRCGQLDSALHEATSRVR-TLENK-------NNLLEIEVNDLRERFSAASSA 536
+ + + G+ + E ++ +LE++ N LLE + L E S
Sbjct: 3223 ALEKEKA--KLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQ 3280
Query: 537 SKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQ-- 594
+ ++ E + + E + K R++++ + +L AQL+ + Q
Sbjct: 3281 RMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDREREL----HAQLQSSDGTGQSR 3336
Query: 595 ------DLLGEYES-LGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEH 647
DLL E + L ++H R+ + LN TE LD+ + ++M + K ++
Sbjct: 3337 PPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDS---LQTRQQMEKDRQVHRKTLQT 3393
Query: 648 ENMLSLRHNSRIHVRPSRANTL 669
E + ++H S+ L
Sbjct: 3394 EQEANTEGQKKMHELQSKVEDL 3415
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 53.5 bits (127), Expect = 1e-06
Identities = 64/258 (24%), Positives = 120/258 (46%), Gaps = 35/258 (13%)
Query: 396 SVNTVDEENTVMV-ASASVSQSQLPGTANSVPECISLTSLEDP--VILSKIRQNLKEKHA 452
S++TV++ +V AS S + +L A I L LE +L ++ ++ + +
Sbjct: 564 SLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELE 623
Query: 453 RHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTL 512
R L +E E++ LK+ LE + +E K+ + + + Q+D +E + ++ T+
Sbjct: 624 RLRTQLLFSHEEELSKLKEDLEIEHRINIE--KLKDNLGIHYKQQIDGLQNEMSQKIETM 681
Query: 513 E-------NKNNLLEIEVNDLRE-RFSAASSASKI-------LQERIEEMRTSSKEKDNT 557
+ K N L +E++ L++ + S +S S+ LQ+ IE +R KEK
Sbjct: 682 QFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGT- 740
Query: 558 IIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTT 617
L+ +Q+L+ E K +KE DL ++ L E+ +KD T
Sbjct: 741 ---LEQEVQELQLKTELLEKQMKEKE----------NDLQEKFAQLEAENSILKDEKKTL 787
Query: 618 ENKLLDAYTQISDLKRMI 635
E+ +L +T +S +R+I
Sbjct: 788 ED-MLKIHTPVSQEERLI 804
Score = 46.2 bits (108), Expect = 2e-04
Identities = 55/245 (22%), Positives = 105/245 (42%), Gaps = 46/245 (18%)
Query: 440 LSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEA-------KEISGVEDWKITNQIL- 491
L K+R+ L E+ + R ++ EI L+Q+L+ E E ++ N +
Sbjct: 2062 LEKMRKFLDEQAIDREHE-RDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKE 2120
Query: 492 -VDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDL--------RERFSAASSASKI-LQ 541
D+C +L + + ++ + LE V +L R+ F A + ++ L+
Sbjct: 2121 KTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLE 2180
Query: 542 ERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAY--------------KLSDDKEAQLK 587
+++ R + K+ I L+ +L+ E EN K S + +L+
Sbjct: 2181 VQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELE 2240
Query: 588 QENKMFQDLLGEYESLGKEHRRVKDALNTTENKLL---------DAYTQISDLKRMISKL 638
QENK+F+D + E LG + DA++T + +L + +I L ++KL
Sbjct: 2241 QENKLFKD---DMEKLGLAIKE-SDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKL 2296
Query: 639 EAQVK 643
+ Q+K
Sbjct: 2297 QQQLK 2301
Score = 42.0 bits (97), Expect = 0.003
Identities = 75/410 (18%), Positives = 170/410 (41%), Gaps = 35/410 (8%)
Query: 402 EENTVMVASASVSQSQLPGTANSVP--ECISLTSLEDPVILSKIRQNLKEKHARHIADLR 459
EE +V++A+ + L GT ++V C+ E V + L++ R +
Sbjct: 3028 EERSVLLAAFRTELTAL-GTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEI 3086
Query: 460 AYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLL 519
+++N K L+ ++ E K + ++L Q S + E + +++++ L
Sbjct: 3087 QALHAQMNGRKITLKREQ----ESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATEL 3142
Query: 520 EIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLS 579
+ +++ E+ A S++ Q ++E + T+ K + + L++ ++++ + + L+
Sbjct: 3143 QEQLSS--EKMVVAELKSELAQTKLE-LETTLKAQHKHLKELEAFRLEVKDKTDEVHLLN 3199
Query: 580 DDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISK-- 637
D ++ K+ ++ L E LG+ R K+ L + L + L ++ +
Sbjct: 3200 DTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQK 3259
Query: 638 --LEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLD 695
L +++E + ML S R L S+ R + + LD
Sbjct: 3260 QLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREM----------SSTLD 3309
Query: 696 TQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLL--IKKQRETSDTPIMRALKELDEG 753
++ + QL+ + G S P S LL ++KQ E + I+ L E ++
Sbjct: 3310 -RERELHAQLQSSDGTG-------QSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKY 3361
Query: 754 KIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQR 803
K+ + T+ + E ++ + +T A+ +K + Q ++ ++
Sbjct: 3362 KL-DSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQ 3410
Score = 34.3 bits (77), Expect = 0.62
Identities = 46/227 (20%), Positives = 96/227 (42%), Gaps = 12/227 (5%)
Query: 424 SVPECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVED 483
++ E ++++ + V+ K Q ++EK I L ++ L+Q+L+ + V +
Sbjct: 2256 AIKESDAMSTQDQHVLFGKFAQIIQEKEVE-IDQLN----EQVTKLQQQLKITTDNKVIE 2310
Query: 484 WKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQER 543
K N+++ D Q++ + + R E + L + L++ + + +
Sbjct: 2311 EK--NELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHS 2368
Query: 544 IEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESL 603
+ E S K + + +I K L E+ E A + + LK+ N L E SL
Sbjct: 2369 LSEEADSLKHQLDVVIAEKLAL---EQQVETANEEMTFMKNVLKETNFKMNQLTQELFSL 2425
Query: 604 GKEHRRVKDALNTTENKLLDAYTQISDLKRMISKL--EAQVKQVEHE 648
+E V+ + EN + A +S K + + E +K +E++
Sbjct: 2426 KRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQ 2472
Score = 30.4 bits (67), Expect = 9.0
Identities = 66/322 (20%), Positives = 125/322 (38%), Gaps = 44/322 (13%)
Query: 375 QNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQSQLPGTANSVPEC---ISL 431
+ ES S Y I + + E + M A+ Q QL V E ++
Sbjct: 3103 EQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQ 3162
Query: 432 TSLEDPVILSKIRQNLKEKHARHIADLRAYY------ESEINSLKQKLEAKEISGVE-DW 484
T LE + LK +H +H+ +L A+ E++ L L +++ E W
Sbjct: 3163 TKLE-------LETTLKAQH-KHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQW 3214
Query: 485 KITNQILVDRCGQLDSALHEATSRVR-TLENK-------NNLLEIEVNDLRERFSAASSA 536
+ + + G+ + E ++ +LE++ N LLE + L E S
Sbjct: 3215 ALEKEKA--KLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQ 3272
Query: 537 SKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQ-- 594
+ ++ E + + E + K R++++ + +L AQL+ + Q
Sbjct: 3273 RMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDREREL----HAQLQSSDGTGQSR 3328
Query: 595 ------DLLGEYES-LGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEH 647
DLL E + L ++H R+ + LN TE LD+ + ++M + K ++
Sbjct: 3329 PPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDS---LQTRQQMEKDRQVHRKTLQT 3385
Query: 648 ENMLSLRHNSRIHVRPSRANTL 669
E + ++H S+ L
Sbjct: 3386 EQEANTEGQKKMHELQSKVEDL 3407
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 53.5 bits (127), Expect = 1e-06
Identities = 46/224 (20%), Positives = 103/224 (45%), Gaps = 16/224 (7%)
Query: 440 LSKIRQNLKEKHARHIADLRAY--YESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQ 497
L++ ++ ++ R++++L+ + E ++ L+ K + WK+ ++ +
Sbjct: 447 LTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQWKLKHK-------K 499
Query: 498 LDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSK----- 552
L+ AL + + V L KNN + E ++L+ + AA + L++ + ++ T
Sbjct: 500 LERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEE 559
Query: 553 --EKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRV 610
K+ + +KS DLE +N+ E++LK+++K+ + E L +E +
Sbjct: 560 LHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAEL 619
Query: 611 KDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLR 654
K + + KLL+ I DL + + L ++ + E L+
Sbjct: 620 KKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLK 663
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/148 (21%), Positives = 69/148 (46%), Gaps = 1/148 (0%)
Query: 502 LHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRL 561
LH +R L ++ L + N R S + + +K E + E +++++ R+
Sbjct: 161 LHGFHQSLRDLSSEQIRLGDDFNRELSRRSRSDAETKRALEELTEKLNEAQKQEVVSDRV 220
Query: 562 KSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHR-RVKDALNTTENK 620
+ RLQ+LE +L + ++ QL + Q+ L + E+ EH +K+ L TE +
Sbjct: 221 ERRLQELEREMRTERELVERRQDQLGLMSLQLQEALKKQEAKADEHEGAIKNKLRQTETE 280
Query: 621 LLDAYTQISDLKRMISKLEAQVKQVEHE 648
++ +R++++ E + + H+
Sbjct: 281 KNQLEQELELSRRLLNQSEGSRETLLHQ 308
Score = 36.6 bits (83), Expect = 0.13
Identities = 47/214 (21%), Positives = 93/214 (43%), Gaps = 31/214 (14%)
Query: 485 KITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERF----SAASSASKI- 539
K N +L R Q + LH ++R +++ LE+EV + + S SKI
Sbjct: 544 KELNDVLTKRALQ-EEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQ 602
Query: 540 ---------LQERIEEMRTSSKEKDNTIIRLKSRLQDLEE-AFENAYKLSDDKEAQLKQE 589
L+E I E++ S + ++ ++ ++DL + A KL++++ A+ K
Sbjct: 603 SQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAK-KAV 661
Query: 590 NKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHEN 649
K DL + +S +E + L L+ +LK + S L++ VK +N
Sbjct: 662 LKDLSDLTAQAKSRDEETATIITQLK------LERDVHQRELKDLTSSLQS-VKTKHEQN 714
Query: 650 MLSL-------RHNSRIHVRPSRANTLATSDVSR 676
+ L + + H+R +A +L ++++
Sbjct: 715 IQELMKHFKKEKSEAENHIRTLKAESLEEKNMAK 748
Score = 36.2 bits (82), Expect = 0.16
Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 19/137 (13%)
Query: 510 RTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLE 569
R +E + LE +++DLR + + ++ AS++ EE++ + KD L S++++L
Sbjct: 352 RGVEREKQDLEKQMSDLRVQLNFSAMASEL-----EEVKRCMERKDKEKAHLASQVENLT 406
Query: 570 EAFENAYKLS--------------DDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALN 615
EN K D EA+ K + +L E K+ R L
Sbjct: 407 RELENGEKQQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERYLSELQ 466
Query: 616 TTENKLLDAYTQISDLK 632
+E +A + DLK
Sbjct: 467 QSEALKEEAEKRREDLK 483
Score = 33.5 bits (75), Expect = 1.1
Identities = 52/241 (21%), Positives = 98/241 (40%), Gaps = 28/241 (11%)
Query: 440 LSKIRQN--LKEKHARHIADLRAYYESEINSLK---QKLEA---KEISGVEDWKITNQIL 491
LS+++Q+ LKE+ + DL+ + I K +KLE K+ V++ N +
Sbjct: 462 LSELQQSEALKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQI 521
Query: 492 VDRCGQLDSALHEATSRVRTLENKNN-------LLEIEVNDLRERFSAASSASKILQ--- 541
+ +L + L+ A ++ L + N L E E++ E+ S L+
Sbjct: 522 LKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSKEEKLRDIKSHQADLELEV 581
Query: 542 ----ERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDL- 596
+ I + + K++ ++K LEE K +A+L + + +DL
Sbjct: 582 KNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQESIKDLS 641
Query: 597 ---LGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMIS--KLEAQVKQVEHENML 651
L +E R K L + A ++ + +I+ KLE V Q E +++
Sbjct: 642 AIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEETATIITQLKLERDVHQRELKDLT 701
Query: 652 S 652
S
Sbjct: 702 S 702
Score = 32.0 bits (71), Expect = 3.1
Identities = 28/149 (18%), Positives = 65/149 (43%), Gaps = 11/149 (7%)
Query: 507 SRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKD----------N 556
+++R E + N LE E+ R + + + + L ++EE+RT + + +
Sbjct: 272 NKLRQTETEKNQLEQELELSRRLLNQSEGSRETLLHQVEELRTQLTKAEGDRKGLQHQVS 331
Query: 557 TIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNT 616
I + +S QD E+ + ++ ++E Q ++ + + ++ E VK +
Sbjct: 332 QISKQQSNYQD-EQGEDWRFRRGVEREKQDLEKQMSDLRVQLNFSAMASELEEVKRCMER 390
Query: 617 TENKLLDAYTQISDLKRMISKLEAQVKQV 645
+ + +Q+ +L R + E Q Q+
Sbjct: 391 KDKEKAHLASQVENLTRELENGEKQQLQM 419
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 52.8 bits (125), Expect = 2e-06
Identities = 131/658 (19%), Positives = 257/658 (39%), Gaps = 74/658 (11%)
Query: 386 SVYTITSNDISVNTVDEENTVMVASASVSQSQLPGTANSVPECISLTS--LEDPVILSKI 443
+V ++ N + +++EN + + ++++ S+ C +L+ +++ L K
Sbjct: 482 TVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKT 541
Query: 444 RQNLKEKHARHIADLRAYYE---SEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDS 500
+ L+E R I L E ++SL+Q+ + + V+D + N+I L
Sbjct: 542 IETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI-------LHE 594
Query: 501 ALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIR 560
++ E +S++ +E + ++ E+ +E+ A L+ + + ++ I
Sbjct: 595 SIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE----LENELHHLEKENELLQKKITN 650
Query: 561 LKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKD---ALNTT 617
LK + + EA E + + +LK+ F++L + ESL KE+ ++ + L
Sbjct: 651 LKITCEKI-EALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 709
Query: 618 ENKLLDAYTQISDLKRMISKLEAQVKQVEHENML---SLRHNSRIHVR-----PSRANTL 669
L A +++ L+ +LE++ +Q++ L S + R+ V
Sbjct: 710 VESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ 769
Query: 670 ATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEE-TCSLGHRSPLEKDSSPGSSST 728
T + S +K I E + Q L+ ++ + LEE S LEK++ T
Sbjct: 770 KTLENSNKK--IQQLESEL---QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQET 824
Query: 729 SLLIKKQRETSDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEK 788
S L K +++ + + K L + K+ + N+ S E
Sbjct: 825 SQLEKDKKQ-----LEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKES 879
Query: 789 CAQQRQKRLNSASQRSSSLPPSNRKSSTPTKREIMLTPVTVAYSPKRSPKENLSPGFSHL 848
C RL + + L ++++ K + L V+ K N +H
Sbjct: 880 CV-----RLKELEKENKELV---KRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE 931
Query: 849 LSK---NESSPIRFDILLDDLDTVPVSTLQRTNPRKQLQFLPLDDSEEKTYS-EKATDNH 904
L K N+ + + DD + S L+ T + L+ EEK + E +
Sbjct: 932 LEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKS------LEIKEEKIAALEARLEES 985
Query: 905 VNHSSCPEPVPNGVKKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFEYTAKIRTLAETER 964
N++ VKK +++ + P+S G D ++ R ET R
Sbjct: 986 TNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPIS----GEDNKWE---RESQETTR 1038
Query: 965 FFDELTKEKDQ-IEAALSRMPSPGGRITLQTRLNQEALEDRLERINRELGSVRMTLKK 1021
EL K KD+ IE + + L+T+L Q LE N L + + L++
Sbjct: 1039 ---ELLKVKDRLIEVERNNATLQAEKQALKTQLKQ------LETQNNNLQAQILALQR 1087
Score = 44.7 bits (104), Expect = 5e-04
Identities = 76/338 (22%), Positives = 139/338 (41%), Gaps = 93/338 (27%)
Query: 370 KNQTFQNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQSQLPGTANSVPECI 429
K Q Q E++ ++ + + +S+ E+NT + + Q + T NS +
Sbjct: 1065 KTQLKQLETQNNNLQAQILALQRQTVSLQ---EQNTTLQTQNAKLQVE-NSTLNS--QST 1118
Query: 430 SLTSLEDPVILSKIR-QNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITN 488
SL + +++ + +N E + DL++ Y+S I +KLE ++
Sbjct: 1119 SLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKD-HEKLELLHERQASEY---- 1173
Query: 489 QILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMR 548
+ L+ + G L SA +KN LE+E DL +R+
Sbjct: 1174 ESLISKHGTLKSA------------HKN--LEVEHRDLEDRY------------------ 1201
Query: 549 TSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHR 608
N +++ K +L+DLE K+ ++ ++ ENK + + EY+ L E+
Sbjct: 1202 -------NQLLKQKGQLEDLE-------KMLKVEQEKMLLENKNHETVAAEYKKLCGEN- 1246
Query: 609 RVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANT 668
D LN T ++LL E +V Q +H+N+ SL +NS++ T
Sbjct: 1247 ---DRLNHTYSQLLK---------------ETEVLQTDHKNLKSLLNNSKLE------QT 1282
Query: 669 LATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLE 706
++ S+ K +Y Q LD + ++NQ E
Sbjct: 1283 RLEAEFSKLK-----EQY-----QQLDITSTKLNNQCE 1310
Score = 43.5 bits (101), Expect = 0.001
Identities = 106/454 (23%), Positives = 182/454 (40%), Gaps = 75/454 (16%)
Query: 463 ESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIE 522
ESE LK+ LE + S +K T ++ V G LD E +TLEN N +
Sbjct: 731 ESEKEQLKKGLELLKAS----FKKTERLEVSYQG-LDI---ENQRLQKTLENSNK----K 778
Query: 523 VNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDK 582
+ L ++ LQ+ +EE++ SSK RL+ ++ + + +L DK
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSK-------RLEQLEKENKSLEQETSQLEKDK 831
Query: 583 EAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQV 642
+ QL++ENK + E + E VK ENK L +I K +L
Sbjct: 832 K-QLEKENKRLRQ-QAEIKDTTLEENNVKIGNLEKENKTLS--KEIGIYKESCVRL---- 883
Query: 643 KQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVD 702
K++E EN ++ AT D+ K L+ E + + L TQ N
Sbjct: 884 KELEKENKELVKR--------------ATIDI---KTLVTLREDLV--SEKLKTQQMN-- 922
Query: 703 NQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSD------TPIMRALKELDEGKIF 756
N LE+ + L K+ L+ ++ T D + + LK+ E K
Sbjct: 923 NDLEKLTHELEKIGLNKER---------LLHDEQSTDDRYKLLESKLESTLKKSLEIKEE 973
Query: 757 KNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQ-QRQKRLNSASQRSSSLPPSNRKSS 815
K + E+++N N + + ++ E Q Q ++R+ +S S + S
Sbjct: 974 KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERES 1033
Query: 816 TPTKREIM-----LTPVTVAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDTVP 870
T RE++ L V + ++ K+ L L ++N + ++ IL TV
Sbjct: 1034 QETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNN--LQAQILALQRQTVS 1091
Query: 871 V----STLQRTNPRKQLQFLPLDDSEEKTYSEKA 900
+ +TLQ N + Q++ L+ ++ A
Sbjct: 1092 LQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA 1125
Score = 42.0 bits (97), Expect = 0.003
Identities = 137/691 (19%), Positives = 264/691 (38%), Gaps = 96/691 (13%)
Query: 366 VDSWKNQTFQNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQSQLPGTANSV 425
+DS+KN TFQ ES + +DEEN +L S+
Sbjct: 679 LDSFKNLTFQLESLEKEN--------------SQLDEENL-----------ELRRNVESL 713
Query: 426 PECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEIS--GVED 483
+C S+ +++++ KE ESE LK+ LE + S E
Sbjct: 714 -KCASMK-------MAQLQLENKE------------LESEKEQLKKGLELLKASFKKTER 753
Query: 484 WKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQE- 542
+++ Q L +L L + +++ LE++ LE+E L++ +SK L++
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813
Query: 543 ----RIEEMRTSSKEKDNTIIRLKS-RLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLL 597
+ E TS EKD + ++ RL+ E + + ++ K L++ENK +
Sbjct: 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Query: 598 GEY-ESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMIS-KLEAQ-----VKQVEHE-N 649
G Y ES + K+ + +D T ++ + ++S KL+ Q ++++ HE
Sbjct: 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELE 933
Query: 650 MLSLRHNSRIHVRPS---RANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLE 706
+ L +H S R L + S K + E I + + +N + QL
Sbjct: 934 KIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLR 993
Query: 707 ETC--------SLGHRSPLEK--DSSPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIF 756
+ +L R E+ SSP S +++ + + +++ L E +
Sbjct: 994 QELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIE--VE 1051
Query: 757 KNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQRSSSLPPSNRK--- 813
+N T ++ +Q ET N + + A QRQ S +++++L N K
Sbjct: 1052 RNNATLQAEKQALKTQLKQLETQ-NNNLQAQILALQRQ--TVSLQEQNTTLQTQNAKLQV 1108
Query: 814 -SSTPTKREIMLTPVTVAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDTVPVS 872
+ST + L ++S EN + ++ + E +D L+ D +
Sbjct: 1109 ENSTLNSQSTSLMNQNAQLLIQQSSLENEN---ESVIKEREDLKSLYDSLIKDHE----- 1160
Query: 873 TLQRTNPRKQLQFLPLDDSEEKTYSEKATDNHVNHSSCPEPVPNGVKKVSVRTAWEKNKS 932
L+ + R+ ++ L S+ T + V H + +K+ EK
Sbjct: 1161 KLELLHERQASEYESL-ISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLK 1219
Query: 933 VSYEQCKPVSVTPQGNDFEYTAKIRTLAETERFFDELTKEKDQIEAALSRMPSPGGRITL 992
V E+ + + EY + +L KE + ++ + S +
Sbjct: 1220 VEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKS----LLN 1275
Query: 993 QTRLNQEALEDRLERINRELGSVRMTLKKFH 1023
++L Q LE ++ + + +T K +
Sbjct: 1276 NSKLEQTRLEAEFSKLKEQYQQLDITSTKLN 1306
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 52.4 bits (124), Expect = 2e-06
Identities = 70/342 (20%), Positives = 133/342 (38%), Gaps = 60/342 (17%)
Query: 415 QSQLPGTANSVPECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLE 474
Q++ G A++ C D +I +KI+ K K A+ +E+ + K+KLE
Sbjct: 898 QAEAEGLADAEERC-------DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE 950
Query: 475 AKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAAS 534
+ +D L+ L + ENK L E+ L E + +
Sbjct: 951 DECSELKKD-----------IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLT 999
Query: 535 SASKILQERIEEMRT---SSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENK 591
K LQE ++ + ++K NT+ + K +L+ + DD E L+QE K
Sbjct: 1000 KEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE----------QQVDDLEGSLEQEKK 1049
Query: 592 MFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQV----KQVEH 647
+ D L + R+++ L + ++D + L + K E ++ ++E
Sbjct: 1050 LRMD-------LERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED 1102
Query: 648 ENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEE 707
E L ++ +I +R L + R + + Q S++ +LEE
Sbjct: 1103 EQALGIQLQKKIKELQARIEELEEEIEAERA-----------SRAKAEKQRSDLSRELEE 1151
Query: 708 TCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKE 749
+ + G++S + + K+RE + R L+E
Sbjct: 1152 ISE-------RLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1186
Score = 42.4 bits (98), Expect = 0.002
Identities = 73/348 (20%), Positives = 132/348 (37%), Gaps = 71/348 (20%)
Query: 449 EKHARHIADLRAYYESEINSLKQKLEAKEIS----GVEDWKITNQILVDRCGQLDSALHE 504
+K R+ + A ++ + +LEA + G E +KI N A E
Sbjct: 1449 DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKN------------AYEE 1496
Query: 505 ATSRVRTLENKNNLLEIEVNDLRERFSAASSA----SKI----------LQERIEEMRTS 550
+ ++ TL+ +N L+ E++DL E+ + KI LQ +EE S
Sbjct: 1497 SLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEAS 1556
Query: 551 SKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQ---------------------- 588
+ ++ I+R++ L ++ + D++ QLK+
Sbjct: 1557 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRND 1616
Query: 589 ----ENKMFQDLLGEYESLGKEHRRVKDAL---NTTENKLLDAYTQISDLKRMISKLEAQ 641
+ KM DL L +R +AL T+ L D + D R L+ Q
Sbjct: 1617 AIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQ 1676
Query: 642 VKQVEHE-NML-----SLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIF-TGQPL 694
+ VE N+L LR R + D S R L+ S+ T + L
Sbjct: 1677 LAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1736
Query: 695 DTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLL---IKKQRETS 739
+T S + ++E+ L E+ + + +++ +KK+++TS
Sbjct: 1737 ETDISQMQGEMEDI--LQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1782
Score = 42.0 bits (97), Expect = 0.003
Identities = 34/178 (19%), Positives = 85/178 (47%), Gaps = 10/178 (5%)
Query: 497 QLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDN 556
++ L ++ ++ + LE K L E NDL+ + A + +ER +++
Sbjct: 864 KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQL-------IK 916
Query: 557 TIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNT 616
T I+L+++++++ E E+ +++ + A+ ++ +L + + L +V+ +
Sbjct: 917 TKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 976
Query: 617 TENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDV 674
TENK+ + +++ L I+KL + K ++ + +L + + NTL + +
Sbjct: 977 TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL---DDLQAEEDKVNTLTKAKI 1031
Score = 33.1 bits (74), Expect = 1.4
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Query: 919 KKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFEYT--AKIRTLAETERFFDELTKEKDQI 976
+K+ A + K E+ K V++ + ND + A+ LA+ E D+L K K Q+
Sbjct: 863 QKIKDELAKSEAKRKELEE-KMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQL 921
Query: 977 EAALSRMPSPG---GRITLQTRLNQEALEDRLERINRELGSVRMTLKK 1021
EA + + I + + LED + +++ + +TL K
Sbjct: 922 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 969
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 52.4 bits (124), Expect = 2e-06
Identities = 70/342 (20%), Positives = 133/342 (38%), Gaps = 60/342 (17%)
Query: 415 QSQLPGTANSVPECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLE 474
Q++ G A++ C D +I +KI+ K K A+ +E+ + K+KLE
Sbjct: 898 QAEAEGLADAEERC-------DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE 950
Query: 475 AKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAAS 534
+ +D L+ L + ENK L E+ L E + +
Sbjct: 951 DECSELKKD-----------IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLT 999
Query: 535 SASKILQERIEEMRT---SSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENK 591
K LQE ++ + ++K NT+ + K +L+ + DD E L+QE K
Sbjct: 1000 KEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE----------QQVDDLEGSLEQEKK 1049
Query: 592 MFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQV----KQVEH 647
+ D L + R+++ L + ++D + L + K E ++ ++E
Sbjct: 1050 LRMD-------LERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED 1102
Query: 648 ENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEE 707
E L ++ +I +R L + R + + Q S++ +LEE
Sbjct: 1103 EQALGIQLQKKIKELQARIEELEEEIEAERA-----------SRAKAEKQRSDLSRELEE 1151
Query: 708 TCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKE 749
+ + G++S + + K+RE + R L+E
Sbjct: 1152 ISE-------RLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1186
Score = 42.4 bits (98), Expect = 0.002
Identities = 73/348 (20%), Positives = 132/348 (37%), Gaps = 71/348 (20%)
Query: 449 EKHARHIADLRAYYESEINSLKQKLEAKEIS----GVEDWKITNQILVDRCGQLDSALHE 504
+K R+ + A ++ + +LEA + G E +KI N A E
Sbjct: 1449 DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKN------------AYEE 1496
Query: 505 ATSRVRTLENKNNLLEIEVNDLRERFSAASSA----SKI----------LQERIEEMRTS 550
+ ++ TL+ +N L+ E++DL E+ + KI LQ +EE S
Sbjct: 1497 SLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEAS 1556
Query: 551 SKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQ---------------------- 588
+ ++ I+R++ L ++ + D++ QLK+
Sbjct: 1557 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRND 1616
Query: 589 ----ENKMFQDLLGEYESLGKEHRRVKDAL---NTTENKLLDAYTQISDLKRMISKLEAQ 641
+ KM DL L +R +AL T+ L D + D R L+ Q
Sbjct: 1617 AIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQ 1676
Query: 642 VKQVEHE-NML-----SLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIF-TGQPL 694
+ VE N+L LR R + D S R L+ S+ T + L
Sbjct: 1677 LAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1736
Query: 695 DTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLL---IKKQRETS 739
+T S + ++E+ L E+ + + +++ +KK+++TS
Sbjct: 1737 ETDISQMQGEMEDI--LQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1782
Score = 42.0 bits (97), Expect = 0.003
Identities = 34/178 (19%), Positives = 85/178 (47%), Gaps = 10/178 (5%)
Query: 497 QLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDN 556
++ L ++ ++ + LE K L E NDL+ + A + +ER +++
Sbjct: 864 KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQL-------IK 916
Query: 557 TIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNT 616
T I+L+++++++ E E+ +++ + A+ ++ +L + + L +V+ +
Sbjct: 917 TKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 976
Query: 617 TENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDV 674
TENK+ + +++ L I+KL + K ++ + +L + + NTL + +
Sbjct: 977 TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL---DDLQAEEDKVNTLTKAKI 1031
Score = 33.1 bits (74), Expect = 1.4
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Query: 919 KKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFEYT--AKIRTLAETERFFDELTKEKDQI 976
+K+ A + K E+ K V++ + ND + A+ LA+ E D+L K K Q+
Sbjct: 863 QKIKDELAKSEAKRKELEE-KMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQL 921
Query: 977 EAALSRMPSPG---GRITLQTRLNQEALEDRLERINRELGSVRMTLKK 1021
EA + + I + + LED + +++ + +TL K
Sbjct: 922 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 969
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 52.0 bits (123), Expect = 3e-06
Identities = 50/240 (20%), Positives = 101/240 (42%), Gaps = 23/240 (9%)
Query: 424 SVPECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVED 483
++ I L L P + RQ KE + +A+ + E+ ++L+A S ++
Sbjct: 300 AIHSTIHLLKLGSPPPHKEARQRRKELRKKQLAE-----QEELERQMKELQAANESKQQE 354
Query: 484 WKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQER 543
+ + L EA SR E K ++E L+ RFS K+++++
Sbjct: 355 LEAVRK-----------KLEEAASRAAEEEKKRLQTQVE---LQARFSTELEREKLIRQQ 400
Query: 544 IEEMRTSSKEKDNTIIRLKSRLQD----LEEAFENAYKLSDDKEAQLKQENKMFQDLLGE 599
+EE + ++ L+D L+EA E+ + D+E K + ++ ++ +
Sbjct: 401 MEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSK 460
Query: 600 YESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRI 659
L K H + A+ TTE + + Q ++ + + Q++Q+E E +L +
Sbjct: 461 RAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEV 520
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 51.6 bits (122), Expect = 4e-06
Identities = 42/196 (21%), Positives = 89/196 (45%), Gaps = 16/196 (8%)
Query: 443 IRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSAL 502
++++L K R A ++E+++L+ +LE KE + K Q + + G +
Sbjct: 506 LKESLTAKEQR-----AAILQTEVDALRLRLEEKETMLNKKTKQI-QDMAEEKGTQAGEI 559
Query: 503 HEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLK 562
H+ + E K N+L+ ++ +L+E+ L+ER++ ++ + D + L+
Sbjct: 560 HDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLE 619
Query: 563 SRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLL 622
L + E E K D++ + KQE E ++ K+ + +K+ ++ + L
Sbjct: 620 EALAEKERTIER-LKEQRDRDEREKQE---------EIDNYKKDLKDLKEKVSLLQGDLS 669
Query: 623 DAYTQISDLKRMISKL 638
+ + DLK S L
Sbjct: 670 EKEASLLDLKEHASSL 685
Score = 47.0 bits (110), Expect = 9e-05
Identities = 50/217 (23%), Positives = 89/217 (41%), Gaps = 30/217 (13%)
Query: 461 YYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLE 520
+ ++++ LK++L +KE E+ K L GQ+ L + + L+ K L
Sbjct: 435 FMKNKVEQLKEELSSKEAQW-EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLT 493
Query: 521 IEVND-------LRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDL-EEAF 572
+ +D L+E +A + ILQ ++ +R +EK+ + + ++QD+ EE
Sbjct: 494 NQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKG 553
Query: 573 ENAYKLSDDK--------------------EAQLKQENKMFQDLLGEYESLGKEHRRVKD 612
A ++ D K + QL+ + K L +SL +
Sbjct: 554 TQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDT 613
Query: 613 ALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHEN 649
AL T E L + I LK + E + KQ E +N
Sbjct: 614 ALTTLEEALAEKERTIERLKEQRDRDERE-KQEEIDN 649
Score = 45.1 bits (105), Expect = 4e-04
Identities = 59/281 (20%), Positives = 113/281 (40%), Gaps = 56/281 (19%)
Query: 400 VDEENTVMVASASVSQSQL--PGTANSVPECISLTSLEDPVILSKIRQNLKEKHARHIAD 457
V EEN M + Q +L N + + S + +P + +N + HA H
Sbjct: 218 VQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQ 277
Query: 458 LRAYY---------ESEINSLKQKLEAKEIS-----------------GVEDWKITNQIL 491
+ + E I + KQ L A++ S ED + T
Sbjct: 278 AKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTR--- 334
Query: 492 VDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSS 551
R + + +H S + E +N++L E++ RF A ++K + ++T
Sbjct: 335 --RLAEAEMHVHHLESLLEQKEKENSMLREEMH---RRFENAPDSAKT-----KALQTVI 384
Query: 552 KEKDNTIIRLKSRLQDLEEAFE----NAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEH 607
+ KD+ I ++ L+DLEE + N ++++E ++KQ E
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQ-----------MEVYRSHS 433
Query: 608 RRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHE 648
+ +K+ + + +L Q +LK+ + L+A++ QV+ E
Sbjct: 434 KFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQE 474
Score = 43.5 bits (101), Expect = 0.001
Identities = 73/356 (20%), Positives = 157/356 (44%), Gaps = 37/356 (10%)
Query: 430 SLTSLEDPVI-LSKIRQNLKEKHARHIADLRAY---YESEINSLKQKLEAKEISGVEDWK 485
+LT+LE+ + + + LKE+ R + + Y+ ++ LK+K+ + + + +
Sbjct: 614 ALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQ-GDLSEKE 672
Query: 486 ITNQILVDRCGQLDSALHEATSRVRTLE-----NKNNLLEIEVNDLRERFSAA--SSASK 538
+ L + L S+ + SR++TLE K L++E + L++ AA + AS
Sbjct: 673 ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKME-SQLKKAHEAALEARASP 731
Query: 539 ILQERIEEM-RTSSKEKDNT------IIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENK 591
+ +RI+ + R ++ KD + + RL L+++E + K + E Q+K +NK
Sbjct: 732 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK 791
Query: 592 MFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKR----MISKLEAQVKQ--- 644
+L + + K+ ++ + E+ L D+ Q+ D R I +LE +++
Sbjct: 792 KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQ 851
Query: 645 --VEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVD 702
E E +L+ ++R + L + +++ A+ S T Q L +++++
Sbjct: 852 ITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS-STQQSLAEKETHLT 910
Query: 703 N-------QLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKELD 751
N LEE + + L S ++ L + ++ + + +E D
Sbjct: 911 NLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKD 966
Score = 31.6 bits (70), Expect = 4.0
Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 14/166 (8%)
Query: 427 ECISLTSLEDPVILSK--IRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDW 484
E + +T+ + V+ + R N EK + + E+ S+K KL + + S E
Sbjct: 848 ESVQITAEREMVLAQEESARTNA-EKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE 906
Query: 485 KITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERI 544
+ +R L+ L ++ + L I D SS+ K QE +
Sbjct: 907 THLTNLRAERRKHLEEVLE--------MKQEALLAAISEKDANIALLELSSSKKKTQEEV 958
Query: 545 EEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQEN 590
++ +EKD + +LK + Q+ + + Y+ K + Q N
Sbjct: 959 AALK---REKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTN 1001
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 51.6 bits (122), Expect = 4e-06
Identities = 42/196 (21%), Positives = 89/196 (45%), Gaps = 16/196 (8%)
Query: 443 IRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSAL 502
++++L K R A ++E+++L+ +LE KE + K Q + + G +
Sbjct: 478 LKESLTAKEQR-----AAILQTEVDALRLRLEEKETMLNKKTKQI-QDMAEEKGTQAGEI 531
Query: 503 HEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLK 562
H+ + E K N+L+ ++ +L+E+ L+ER++ ++ + D + L+
Sbjct: 532 HDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLE 591
Query: 563 SRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLL 622
L + E E K D++ + KQE E ++ K+ + +K+ ++ + L
Sbjct: 592 EALAEKERTIER-LKEQRDRDEREKQE---------EIDNYKKDLKDLKEKVSLLQGDLS 641
Query: 623 DAYTQISDLKRMISKL 638
+ + DLK S L
Sbjct: 642 EKEASLLDLKEHASSL 657
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/266 (19%), Positives = 109/266 (40%), Gaps = 30/266 (11%)
Query: 412 SVSQSQLPGTANSVPECISLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQ 471
S+ + ++ + P+ +L+ + + + + E+ R + + +S +L
Sbjct: 358 SMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSN-GALST 416
Query: 472 KLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVND------ 525
+ +E+ +E ++ ++ + ++ GQ+ L + + L+ K L + +D
Sbjct: 417 EEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 476
Query: 526 -LRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDL-EEAFENAYKLSDDK- 582
L+E +A + ILQ ++ +R +EK+ + + ++QD+ EE A ++ D K
Sbjct: 477 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKD 536
Query: 583 -------------------EAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLD 623
+ QL+ + K L +SL + AL T E L +
Sbjct: 537 MLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAE 596
Query: 624 AYTQISDLKRMISKLEAQVKQVEHEN 649
I LK + E + KQ E +N
Sbjct: 597 KERTIERLKEQRDRDERE-KQEEIDN 621
Score = 43.5 bits (101), Expect = 0.001
Identities = 73/356 (20%), Positives = 157/356 (44%), Gaps = 37/356 (10%)
Query: 430 SLTSLEDPVI-LSKIRQNLKEKHARHIADLRAY---YESEINSLKQKLEAKEISGVEDWK 485
+LT+LE+ + + + LKE+ R + + Y+ ++ LK+K+ + + + +
Sbjct: 586 ALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQ-GDLSEKE 644
Query: 486 ITNQILVDRCGQLDSALHEATSRVRTLE-----NKNNLLEIEVNDLRERFSAA--SSASK 538
+ L + L S+ + SR++TLE K L++E + L++ AA + AS
Sbjct: 645 ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKME-SQLKKAHEAALEARASP 703
Query: 539 ILQERIEEM-RTSSKEKDNT------IIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENK 591
+ +RI+ + R ++ KD + + RL L+++E + K + E Q+K +NK
Sbjct: 704 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK 763
Query: 592 MFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKR----MISKLEAQVKQ--- 644
+L + + K+ ++ + E+ L D+ Q+ D R I +LE +++
Sbjct: 764 KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQ 823
Query: 645 --VEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVD 702
E E +L+ ++R + L + +++ A+ S T Q L +++++
Sbjct: 824 ITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS-STQQSLAEKETHLT 882
Query: 703 N-------QLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKELD 751
N LEE + + L S ++ L + ++ + + +E D
Sbjct: 883 NLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKD 938
Score = 31.6 bits (70), Expect = 4.0
Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 14/166 (8%)
Query: 427 ECISLTSLEDPVILSK--IRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDW 484
E + +T+ + V+ + R N EK + + E+ S+K KL + + S E
Sbjct: 820 ESVQITAEREMVLAQEESARTNA-EKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE 878
Query: 485 KITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERI 544
+ +R L+ L ++ + L I D SS+ K QE +
Sbjct: 879 THLTNLRAERRKHLEEVLE--------MKQEALLAAISEKDANIALLELSSSKKKTQEEV 930
Query: 545 EEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQEN 590
++ +EKD + +LK + Q+ + + Y+ K + Q N
Sbjct: 931 AALK---REKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTN 973
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 51.6 bits (122), Expect = 4e-06
Identities = 54/248 (21%), Positives = 108/248 (43%), Gaps = 38/248 (15%)
Query: 447 LKEKHARHIADLRAYYESEINS------LKQKLEA--------------KEISGVEDWKI 486
LK H R + +++ ++EI S +K+K+E + + + +
Sbjct: 1590 LKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRN 1649
Query: 487 TNQILVDRCGQLDSALH---EATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQ-- 541
T IL D LD A+ + ++ +E + NL++ EV +LR K+ +
Sbjct: 1650 TQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQE 1709
Query: 542 -----ERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQ---ENKMF 593
ER++ + T + NT +L++ + ++ E+ + + + E + K+ + M
Sbjct: 1710 LLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMM 1769
Query: 594 QDLLGEYESLGKEHRRVKDALNTTENKL---LDAYTQIS--DLKRMISKLEAQVKQVEHE 648
+ L + + R+K + T L LD Q++ K+ I KLEA+V+++E E
Sbjct: 1770 AEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESE 1829
Query: 649 NMLSLRHN 656
+HN
Sbjct: 1830 VESEQKHN 1837
Score = 50.1 bits (118), Expect = 1e-05
Identities = 66/321 (20%), Positives = 124/321 (38%), Gaps = 53/321 (16%)
Query: 436 DPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRC 495
D +I +KI+ K K A+ +E+ + K+KLE + +D
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD-----------I 958
Query: 496 GQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTS---SK 552
L+ L + ENK L E+ L E + + K LQE ++ +
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEE 1018
Query: 553 EKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKD 612
+K NT+ + K++L+ + DD E L+QE K+ D L + R+++
Sbjct: 1019 DKVNTLTKAKTKLE----------QQVDDLEGSLEQEKKLCMD-------LERAKRKLEG 1061
Query: 613 ALNTTENKLLDAYTQISDLKRMISKLEAQVK----QVEHENMLSLRHNSRIHVRPSRANT 668
L + +D L + K E ++ ++E E L+++ +I +R
Sbjct: 1062 DLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEE 1121
Query: 669 LATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSST 728
L + R + + Q S++ +LEE + + G++S
Sbjct: 1122 LEEEIEAERA-----------SRAKAEKQRSDLSRELEEISE-------RLEEAGGATSA 1163
Query: 729 SLLIKKQRETSDTPIMRALKE 749
+ + K+RE + R L+E
Sbjct: 1164 QIEMNKKREAEFQKMRRDLEE 1184
Score = 46.6 bits (109), Expect = 1e-04
Identities = 59/303 (19%), Positives = 128/303 (42%), Gaps = 28/303 (9%)
Query: 502 LHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRL 561
L + ++ + LE K L E NDL+ + A + A +ER +++ T I+L
Sbjct: 867 LAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQL-------IKTKIQL 919
Query: 562 KSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKL 621
+++++++ E E+ +++ + A+ ++ +L + + L +V+ + TENK+
Sbjct: 920 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 979
Query: 622 LDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLI 681
+ +++ L I+KL + K ++ + +L + + + NTL T ++ + +
Sbjct: 980 KNLTEEMAGLDETIAKLTKEKKALQEAHQQTL---DDLQMEEDKVNTL-TKAKTKLEQQV 1035
Query: 682 PGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDT 741
E S+ + L +LE L S ++ ++ + L KK+ E S+
Sbjct: 1036 DDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLK-KKEFEMSNL 1094
Query: 742 PIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSAS 801
+GKI + E+ + + E E+ +R R +
Sbjct: 1095 ----------QGKI------EDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
Query: 802 QRS 804
QRS
Sbjct: 1139 QRS 1141
Score = 44.3 bits (103), Expect = 6e-04
Identities = 46/199 (23%), Positives = 85/199 (42%), Gaps = 14/199 (7%)
Query: 464 SEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEV 523
SE+ + K E I E+ + + L R + + S+ +LE L+ EV
Sbjct: 1370 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEV 1429
Query: 524 NDLR---ERFSAASSASKILQERIEEMRTSSKEK-DNTIIRLKSRLQDLE----EAFE-- 573
DL ER +AA A Q +++ K+K + T L++ ++ E F+
Sbjct: 1430 EDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVK 1489
Query: 574 NAYKLSDDKEAQLKQENKMFQ----DLLGEYESLGKEHRRVKDALNTTENKLLDAYTQIS 629
NAY+ S D LK+ENK Q DL + GK ++ +++ + T +
Sbjct: 1490 NAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLE 1549
Query: 630 DLKRMISKLEAQVKQVEHE 648
+ + + E ++ +++ E
Sbjct: 1550 EAEASLEHEEGKILRIQLE 1568
Score = 42.4 bits (98), Expect = 0.002
Identities = 50/232 (21%), Positives = 97/232 (41%), Gaps = 23/232 (9%)
Query: 440 LSKIRQNLKE--KHARHIADLRAYYESEINSLKQKLEAKEIS-GVEDWKIT------NQI 490
+S + + + E KH + ++ + E + L+ LE E S E+ KI NQ+
Sbjct: 1513 ISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQV 1572
Query: 491 L--VDR-CGQLDSALHEAT-SRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEE 546
+DR + D L + + +R +E+ + L+ E+ + L E +
Sbjct: 1573 KSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQ 1632
Query: 547 MRTSSKEKDNTIIRLKSR---LQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESL 603
+ ++++ + L++ L+D + ++A + DD + QL + + E E L
Sbjct: 1633 LNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEEL 1692
Query: 604 GKEHRRVKDALNTTENKLLDA-------YTQISDLKRMISKLEAQVKQVEHE 648
R + E +LLDA +TQ + L KLE + Q++ E
Sbjct: 1693 RASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGE 1744
Score = 32.7 bits (73), Expect = 1.8
Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 939 KPVSVTPQGNDFEYT--AKIRTLAETERFFDELTKEKDQIEAALSRMPSPG---GRITLQ 993
K V++ + ND + A+ LA+ E D+L K K Q+EA + + I +
Sbjct: 880 KMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAE 939
Query: 994 TRLNQEALEDRLERINRELGSVRMTLKK 1021
+ LED + +++ + +TL K
Sbjct: 940 LTAKKRKLEDECSELKKDIDDLELTLAK 967
Score = 30.8 bits (68), Expect = 6.9
Identities = 43/226 (19%), Positives = 90/226 (39%), Gaps = 29/226 (12%)
Query: 448 KEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCG---QLDSALHE 504
K K + + DL E E L LE + D K+ + +D QL+ L +
Sbjct: 1028 KTKLEQQVDDLEGSLEQE-KKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKK 1086
Query: 505 ATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSR 564
+ L+ K + L+++ + + L+E IE R S + + L
Sbjct: 1087 KEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1146
Query: 565 LQDLEEAFENA-------YKLSDDKEAQLKQENKMFQDLLGEYES----LGKEH------ 607
L+++ E E A +++ +EA+ ++ + ++ ++E+ L K+H
Sbjct: 1147 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAE 1206
Query: 608 --------RRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQV 645
+RVK L +++L ++ +SK +A +++
Sbjct: 1207 LGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKM 1252
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 51.2 bits (121), Expect = 5e-06
Identities = 124/656 (18%), Positives = 256/656 (39%), Gaps = 92/656 (14%)
Query: 386 SVYTITSNDISVNTVDEENTVMVASASVSQSQLPGTANSVPECISLTS--LEDPVILSKI 443
+V ++ N + +++EN + + ++++ S+ C +L+ +++ L K
Sbjct: 482 TVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKT 541
Query: 444 RQNLKEKHARHIADLRAYYE---SEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDS 500
+ L+E R I L E ++SL+Q+ + + V+D + N+I L
Sbjct: 542 IETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI-------LHE 594
Query: 501 ALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIR 560
++ E +S++ +E + ++ E+ +E+ ER EE+ +N +
Sbjct: 595 SIKETSSKLSKIEFEKRQIKKELEHYKEK-----------GERAEEL-------ENELHH 636
Query: 561 LKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENK 620
L+ + L++ N K++ +K L+QEN L +E+R++K L++ +N
Sbjct: 637 LEKENELLQKKITN-LKITCEKIEALEQEN----------SELERENRKLKKTLDSFKN- 684
Query: 621 LLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWL 680
L + LE + Q++ EN L LR N V + ++ + +
Sbjct: 685 ----------LTFQLESLEKENSQLDEEN-LELRRN----VESLKCASMKMAQLQLENKE 729
Query: 681 IPGAEYSIFTGQPLDTQDSNVDNQLEETC-SLGHRSPLEKDSSPGSSSTSLLIKKQRETS 739
+ + + G L +LE + L + + + S+ ++ + +
Sbjct: 730 LESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDL 789
Query: 740 DTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNS 799
+ K L+E KI Q EKE+ S E + +K ++ KRL
Sbjct: 790 EMENQTLQKNLEELKISSKRLEQLEKENKS------LEQETSQLEKDKKQLEKENKRLRQ 843
Query: 800 ASQ-RSSSLPPSNRKSSTPTKREIMLTPVTVAYSPKRSPKENLSPGFSHLLSKNESSPIR 858
++ + ++L +N K K L+ Y + L L+ +
Sbjct: 844 QAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Query: 859 FDILLDDLDTVPVSTLQRTNPRK----QLQFLPLDDSEEKTYSEKATDNHVNHSSCPEPV 914
L +DL + + T Q N + +L+ + L + E + E++TD+
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGL-NKERLLHDEQSTDD----------- 951
Query: 915 PNGVKKVSVRTAWEKNKSVSYEQCKPVSVTPQ-GNDFEYTAKIRTLAETERFFDELTKEK 973
+ K + + KS+ ++ K ++ + Y ++R +T + E K++
Sbjct: 952 -SRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQR 1010
Query: 974 DQIEAALSRMPSPGGRITLQTRLNQEA------LEDRL---ERINRELGSVRMTLK 1020
E + P G R +QE ++DRL ER N L + + LK
Sbjct: 1011 QDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALK 1066
Score = 47.0 bits (110), Expect = 9e-05
Identities = 109/454 (24%), Positives = 180/454 (39%), Gaps = 74/454 (16%)
Query: 463 ESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIE 522
ESE LK+ LE + S +K T ++ V G LD E +TLEN N +
Sbjct: 731 ESEKEQLKKGLELLKAS----FKKTERLEVSYQG-LDI---ENQRLQKTLENSNK----K 778
Query: 523 VNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDK 582
+ L ++ LQ+ +EE++ SSK RL+ ++ + + +L DK
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSK-------RLEQLEKENKSLEQETSQLEKDK 831
Query: 583 EAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQV 642
+ QL++ENK + E + E VK ENK L +I K +L
Sbjct: 832 K-QLEKENKRLRQ-QAEIKDTTLEENNVKIGNLEKENKTLS--KEIGIYKESCVRL---- 883
Query: 643 KQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVD 702
K++E EN ++ AT D+ K L+ E + + L TQ N
Sbjct: 884 KELEKENKELVKR--------------ATIDI---KTLVTLREDLV--SEKLKTQQMN-- 922
Query: 703 NQLE------ETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIF 756
N LE E L L + S S LL K T ++ E+ E KI
Sbjct: 923 NDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLEST-----LKKSLEIKEEKIA 977
Query: 757 KNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQ-QRQKRLNSASQRSSSLPPSNRKSS 815
+ E+++N N + + ++ E Q Q ++R+ +S S + S
Sbjct: 978 ---ALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERES 1034
Query: 816 TPTKREIM-----LTPVTVAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDTVP 870
T RE++ L V + ++ K+ L L ++N + ++ IL TV
Sbjct: 1035 QETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNN--LQAQILALQRQTVS 1092
Query: 871 V----STLQRTNPRKQLQFLPLDDSEEKTYSEKA 900
+ +TLQ N + Q++ L+ ++ A
Sbjct: 1093 LQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA 1126
Score = 44.7 bits (104), Expect = 5e-04
Identities = 76/338 (22%), Positives = 139/338 (41%), Gaps = 93/338 (27%)
Query: 370 KNQTFQNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQSQLPGTANSVPECI 429
K Q Q E++ ++ + + +S+ E+NT + + Q + T NS +
Sbjct: 1066 KTQLKQLETQNNNLQAQILALQRQTVSLQ---EQNTTLQTQNAKLQVE-NSTLNS--QST 1119
Query: 430 SLTSLEDPVILSKIR-QNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITN 488
SL + +++ + +N E + DL++ Y+S I +KLE ++
Sbjct: 1120 SLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKD-HEKLELLHERQASEY---- 1174
Query: 489 QILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMR 548
+ L+ + G L SA +KN LE+E DL +R+
Sbjct: 1175 ESLISKHGTLKSA------------HKN--LEVEHRDLEDRY------------------ 1202
Query: 549 TSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHR 608
N +++ K +L+DLE K+ ++ ++ ENK + + EY+ L E+
Sbjct: 1203 -------NQLLKQKGQLEDLE-------KMLKVEQEKMLLENKNHETVAAEYKKLCGEN- 1247
Query: 609 RVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANT 668
D LN T ++LL E +V Q +H+N+ SL +NS++ T
Sbjct: 1248 ---DRLNHTYSQLLK---------------ETEVLQTDHKNLKSLLNNSKLE------QT 1283
Query: 669 LATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLE 706
++ S+ K +Y Q LD + ++NQ E
Sbjct: 1284 RLEAEFSKLK-----EQY-----QQLDITSTKLNNQCE 1311
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 51.2 bits (121), Expect = 5e-06
Identities = 97/524 (18%), Positives = 200/524 (38%), Gaps = 74/524 (14%)
Query: 400 VDEENTVMVASASVSQSQLPGTANSVPECISLTSLEDPVILSKIRQNLKEKHARHIADLR 459
++E+ ++ + Q Q+ A+S+ + D +I +KI+ K K A+
Sbjct: 877 LEEKMVTLMQEKNDLQLQVQAEADSLADAEERC---DQLIKTKIQLEAKIKEVTERAEDE 933
Query: 460 AYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLL 519
+E+ + K+KLE + +D L+ L + ENK L
Sbjct: 934 EEINAELTAKKRKLEDECSELKKD-----------IDDLELTLAKVEKEKHATENKVKNL 982
Query: 520 EIEVNDLRERFSAASSASKILQERIEEM---RTSSKEKDNTI----IRLKSRLQDLEEAF 572
E+ L E + + K LQE ++ + ++K NT+ I+L+ ++ DLE +
Sbjct: 983 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1042
Query: 573 ENAYKLSDD-------KEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAY 625
E K+ D E LK + D+ + + L ++ ++ + ++ ++K+ D
Sbjct: 1043 EQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQ 1102
Query: 626 TQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAE 685
L++ I +L+A+++++E E + RA SR K
Sbjct: 1103 ALGMQLQKKIKELQARIEELEEE------------IEAERA--------SRAK------- 1135
Query: 686 YSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMR 745
+ Q S++ +LEE + + G++S + + K+RE +
Sbjct: 1136 --------AEKQRSDLSRELEEISE-------RLEEAGGATSAQIEMNKKREAE---FQK 1177
Query: 746 ALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQRSS 805
++L+E + T ++ ++ E N R +K +++ + +S
Sbjct: 1178 MRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1237
Query: 806 SLPPSNRKSSTPTKREIMLTPVTVAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDD 865
++ ++ K L K ++ L + ++ ++ + LD+
Sbjct: 1238 NMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDE 1297
Query: 866 LDTVPVSTLQRTNPRKQLQFLPLDDSEEKTYSEKATDNHVNHSS 909
DT+ VS L R Q L E+ K+ H SS
Sbjct: 1298 KDTL-VSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSS 1340
Score = 45.1 bits (105), Expect = 4e-04
Identities = 62/310 (20%), Positives = 128/310 (41%), Gaps = 42/310 (13%)
Query: 502 LHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRL 561
L + ++ + LE K L E NDL+ + A + + +ER +++ T I+L
Sbjct: 867 LAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQL-------IKTKIQL 919
Query: 562 KSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKL 621
+++++++ E E+ +++ + A+ ++ +L + + L +V+ + TENK+
Sbjct: 920 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 979
Query: 622 LDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLI 681
+ +++ L I+KL + K ++ + +L + + NTL + +
Sbjct: 980 KNLTEEMAGLDETIAKLTKEKKALQEAHQQTL---DDLQAEEDKVNTLTKAKIK------ 1030
Query: 682 PGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDT 741
L+ Q +++ LE+ + R LE+ L Q T D
Sbjct: 1031 ------------LEQQVDDLEGSLEQEKKI--RMDLERAKRKLEGDLKL---AQESTMD- 1072
Query: 742 PIMRALKELDE---GKIFKNWGTQTEKEDTS----NINPRQTETSVNASRSPEKCAQQRQ 794
I ++LDE K F+ G Q++ ED + + E E+ +R
Sbjct: 1073 -IENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERA 1131
Query: 795 KRLNSASQRS 804
R + QRS
Sbjct: 1132 SRAKAEKQRS 1141
Score = 42.4 bits (98), Expect = 0.002
Identities = 49/226 (21%), Positives = 92/226 (40%), Gaps = 41/226 (18%)
Query: 447 LKEKHARHIADLRAYYESEINSLKQ--KLEAKEISGVEDWKITNQILVDRCGQLDSALHE 504
+K H R + +++ ++EI S +L+ K + + +I QL+ A
Sbjct: 1590 MKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI----------QLNHANRM 1639
Query: 505 ATSRVRTLENKNNLLEI----------EVNDLRERFSAASSASKILQERIEEMRTSSKEK 554
A +R N +L+ DL+E+ + + +LQ IEE+R + ++
Sbjct: 1640 AAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQT 1699
Query: 555 DNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQD---LLGEYESLGKEHRRVK 611
+ + K Q+L +A E L + + + K+ D + GE E + +E R +
Sbjct: 1700 ERS---RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAE 1756
Query: 612 DALNTTENKLLDAYTQISDLK----------RMISKLEAQVKQVEH 647
+ + + DA +LK RM LE VK ++H
Sbjct: 1757 E---KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Score = 42.0 bits (97), Expect = 0.003
Identities = 70/357 (19%), Positives = 139/357 (38%), Gaps = 64/357 (17%)
Query: 449 EKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSR 508
+K R+ + A ++ + +LEA + E ++ ++ ++ +A E+ +
Sbjct: 1447 DKKQRNFDKILAEWKQKCEETHAELEASQ---KESRSLSTELF-----KIKNAYEESLDQ 1498
Query: 509 VRTLENKNNLLEIEVNDLRERFSAASSA----SKI----------LQERIEEMRTSSKEK 554
+ TL+ +N L+ E++DL E+ + KI LQ +EE S + +
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHE 1558
Query: 555 DNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQ-------------------------- 588
+ I+R++ L ++ + D++ Q+K+
Sbjct: 1559 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRL 1618
Query: 589 ENKMFQDLLGEYESLGKEHRRVKDALNTTENK---LLDAYTQISDLKRMISKLEAQVKQV 645
+ KM DL L +R +AL N L D + D R L+ Q+ V
Sbjct: 1619 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMV 1678
Query: 646 EHE-NML-----SLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIF-TGQPLDTQD 698
E N+L LR R + D S R L+ S+ T + L+T
Sbjct: 1679 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1738
Query: 699 SNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLL---IKKQRETSDTPIMRALKELDE 752
S + ++E+ + E+ + + +++ +KK+++TS + R K L++
Sbjct: 1739 SQIQGEMEDIIQEARNA--EEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKNLEQ 1792
Score = 33.1 bits (74), Expect = 1.4
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 5/88 (5%)
Query: 939 KPVSVTPQGNDFEYT--AKIRTLAETERFFDELTKEKDQIEAALSRMPSPG---GRITLQ 993
K V++ + ND + A+ +LA+ E D+L K K Q+EA + + I +
Sbjct: 880 KMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAE 939
Query: 994 TRLNQEALEDRLERINRELGSVRMTLKK 1021
+ LED + +++ + +TL K
Sbjct: 940 LTAKKRKLEDECSELKKDIDDLELTLAK 967
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 50.8 bits (120), Expect = 6e-06
Identities = 77/363 (21%), Positives = 148/363 (40%), Gaps = 56/363 (15%)
Query: 432 TSLEDPVILSKIRQNLKEKHARHIADLRAY-------YESEINSLKQK--LEAKEISG-V 481
T LED + + +Q L+ K + +A+L+ +E++I ++Q+ +E+S +
Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQL 1212
Query: 482 EDWKITNQILVDRCGQLDSALHEATSRVRTL-------ENKNNLLEIEVNDL-------- 526
E K L L++ E V+ L E+K L+ +V +L
Sbjct: 1213 EQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD 1272
Query: 527 RERFSAASSASKILQERIEEMRTSSKEKDNTIIR-------LKSRLQDLEEAFENAYKLS 579
R R A ASK LQ ++ + T +E + I+ L+S+LQD +E + +
Sbjct: 1273 RLRVELAEKASK-LQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQK 1331
Query: 580 DDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLE 639
+ ++++Q L E SL ++ ++A E ++L +Q++D K+ +
Sbjct: 1332 LNLSSRIRQ-------LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDL 1384
Query: 640 AQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRK--------WLIPGAEYSIFTG 691
++ +E L+ + R LA + + K L ++
Sbjct: 1385 GTIESLEEAKKKLLKDAEALSQR-LEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVA 1443
Query: 692 QPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKELD 751
L+ + D L E S+ R E+D + + +++ET + RAL+E
Sbjct: 1444 SNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEA-------REKETKALSLARALEEAL 1496
Query: 752 EGK 754
E K
Sbjct: 1497 EAK 1499
Score = 48.9 bits (115), Expect = 2e-05
Identities = 55/285 (19%), Positives = 114/285 (40%), Gaps = 41/285 (14%)
Query: 402 EENTVMVASASVSQSQLPGTANSVPECIS--LTSLEDPVILSKIRQNLKEKHARHIADLR 459
+ T + A A +++L + E + + +E+ ++I QN K+K HI DL
Sbjct: 897 QAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLE 956
Query: 460 AYYESEINSLKQKLEAKEISG-VEDWKITNQILV----------------DRCGQLDSAL 502
+ E +QKL+ ++++ + K+ +IL+ DR + S L
Sbjct: 957 EQLDEE-EGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQL 1015
Query: 503 HEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKIL---------------------Q 541
E + + L N E+ ++DL ER + L Q
Sbjct: 1016 AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQ 1075
Query: 542 ERIEEMRTSSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYE 601
+I+E++ +K+ + +R D NA K+ + +AQ+ + + F+
Sbjct: 1076 AQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRN 1135
Query: 602 SLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVE 646
K+ R + + L + +L D + + + +K E +V +++
Sbjct: 1136 KAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELK 1180
Score = 47.0 bits (110), Expect = 9e-05
Identities = 92/464 (19%), Positives = 186/464 (40%), Gaps = 61/464 (13%)
Query: 430 SLTSLEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQ 489
S +LE V + + E + D + E + ++K + E + E + +
Sbjct: 1533 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592
Query: 490 ILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRT 549
+L+ + +L++ L + + +EI++ DL + AA+ A E I+++R
Sbjct: 1593 LLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKAR---DEVIKQLR- 1648
Query: 550 SSKEKDNTIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKE--- 606
+L+++++D + E A D+ AQ K+ K + L E L +E
Sbjct: 1649 ----------KLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELAS 1698
Query: 607 HRRVKDALNTTENKLLDAYTQISDLKRMI----SKLEAQVKQVEHE------NMLSLRHN 656
R + ++L D T + K + +LEA++ Q+E E NM L N
Sbjct: 1699 SERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELL--N 1756
Query: 657 SRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEE--------- 707
R + +TL + R A+ S Q L+ Q+ + +L+E
Sbjct: 1757 DRFRKTTLQVDTLNAELAAERS----AAQKSDNARQQLERQNKELKAKLQELEGAVKSKF 1812
Query: 708 -------TCSLGH-RSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKELDEGKIFKNW 759
+G LE+++ +++ L+ + +++ + ++ DE + +
Sbjct: 1813 KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEI----FMQVEDERRHADQY 1868
Query: 760 GTQTEKEDTSNIN-PRQTETSVNASRSPEKCAQQRQKRLNSASQRSSSLPPSNRKSSTPT 818
Q EK + RQ E + + ++ Q+ L+ A++ + L +R+ ST
Sbjct: 1869 KEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL---SREVSTLK 1925
Query: 819 KREIMLTPVTVAYSPKRSPKENLS-PGFSHLLSKNESSPIRFDI 861
R P +++S RS + L G S LS +++ D+
Sbjct: 1926 NRLRRGGP--ISFSSSRSGRRQLHLEGASLELSDDDTESKTSDV 1967
Score = 46.2 bits (108), Expect = 2e-04
Identities = 100/522 (19%), Positives = 208/522 (39%), Gaps = 88/522 (16%)
Query: 441 SKIRQNLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDS 500
+K+ L+E +H L E N L ++L+A+ E ++ ++ + +L+
Sbjct: 869 TKVEGELEEMERKHQQLLE-----EKNILAEQLQAETELFAEAEEMRARLAAKK-QELEE 922
Query: 501 ALHEATSRVRTLENKNNLLEIE-------VNDLRERFSAASSASKILQ----------ER 543
LH+ SRV E +N +L+ E + DL E+ A + LQ ++
Sbjct: 923 ILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKK 982
Query: 544 IEEMRTSSKEKDNTIIRLK-----------SRLQDLEEAFENAYKLSD-------DKEAQ 585
+EE +++++ I+ K S+L + EE +N K+ + D E +
Sbjct: 983 MEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEER 1042
Query: 586 LKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVK-- 643
LK+E K Q+L K R++ ++++ + QI +LK ++K E +++
Sbjct: 1043 LKKEEKTRQEL-------EKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGA 1095
Query: 644 QVEHENMLSLRHNSRIHVRPSRA----------NTLATSDVSRRKWLIPGAEYSIFTGQP 693
++ ++N+ VR +A + A+ + + ++ E +
Sbjct: 1096 LARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL 1155
Query: 694 LDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALKELDEG 753
DT D+ Q T + L+K + + I+ R+ T + ++L++
Sbjct: 1156 EDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQA 1215
Query: 754 KIFK-NWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQRSSSLPPSNR 812
K FK N + +T N ++ V + + ++ ++K+L++ Q +
Sbjct: 1216 KRFKANLEKNKQGLETDN---KELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD 1272
Query: 813 KSSTPTKREIMLTPVTVAYSPKRSPKENLSPGFSHLLSKNESSPIRF--------DILLD 864
+ + V + K S +N S LL + E I+F L D
Sbjct: 1273 R-------------LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQD 1319
Query: 865 DLDTVPVSTLQRTNPRKQLQFLPLDDS---EEKTYSEKATDN 903
+ + T Q+ N +++ L + + E++ E+A N
Sbjct: 1320 TQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN 1361
Score = 45.4 bits (106), Expect = 3e-04
Identities = 58/302 (19%), Positives = 125/302 (41%), Gaps = 29/302 (9%)
Query: 360 HTKASPVDSWKNQTFQNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQSQLP 419
H K S D + + + S+ + +V T+ + +++ A+ +SQL
Sbjct: 1265 HAKVSEGDRLRVELAEKASKLQNELDNVSTL------LEEAEKKGIKFAKDAASLESQLQ 1318
Query: 420 GTANSVPE----CISLTS----LEDPVILSKIRQNLKEKHARHIADLRAYYESEINSLKQ 471
T + E ++L+S LE+ + +Q +E+ +++ +S++ K+
Sbjct: 1319 DTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKK 1378
Query: 472 KLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDL----- 526
K++ ++ +E + + L+ L L E LE N L+ E++DL
Sbjct: 1379 KVD-DDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLD 1437
Query: 527 --RERFSAASSASKILQERIEEMRTSS----KEKDNTIIRLK---SRLQDLEEAFENAYK 577
R+ S K + + E ++ S +E+D + ++ L A E A +
Sbjct: 1438 HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALE 1497
Query: 578 LSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISK 637
++ E Q KQ +DL+ + +GK ++ + E ++ + TQ+ +L+ +
Sbjct: 1498 AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 638 LE 639
E
Sbjct: 1558 TE 1559
Score = 37.4 bits (85), Expect = 0.073
Identities = 50/233 (21%), Positives = 95/233 (40%), Gaps = 36/233 (15%)
Query: 448 KEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATS 507
KE+ R LRA E ++S K + +E K + L + ++ + L E
Sbjct: 1499 KEEFERQNKQLRADMEDLMSSKDDV--GKNVHELEKSK---RALEQQVEEMRTQLEELED 1553
Query: 508 RVRTLENKNNLLEIEVN--------DLRERFSAASSASKILQERIEEMRTSSK-EKDNTI 558
++ E+ LE+ + DL+ R ++L +++ E+ + E+
Sbjct: 1554 ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRA 1613
Query: 559 IRLKSR------LQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKD 612
+ + S+ L+DLE E A K D+ QL++ +D E E E R +D
Sbjct: 1614 LAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELE----EARASRD 1669
Query: 613 ALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSR 665
+ + Q + ++ + LEA++ Q++ E L+ +R H R
Sbjct: 1670 ----------EIFAQSKESEKKLKSLEAEILQLQEE--LASSERARRHAEQER 1710
Score = 30.4 bits (67), Expect = 9.0
Identities = 53/248 (21%), Positives = 106/248 (42%), Gaps = 29/248 (11%)
Query: 415 QSQLPGTANSVPECI-SLTSLEDPVILSKIRQNLKEKHARHIADLRAY--YESEINSLKQ 471
QSQL T V + + ++ SLE+ K+ ++ + R AY E N L+Q
Sbjct: 1370 QSQLADTKKKVDDDLGTIESLEEAK--KKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ 1427
Query: 472 KLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSRVRTLENKNNLLEIEVNDLRERFS 531
+L+ + ++ + L + + D L E S + + E E RE+ +
Sbjct: 1428 ELDDLTVDLDHQRQVASN-LEKKQKKFDQLLAEEKSISARYAEERDRAEAEA---REKET 1483
Query: 532 AASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDL----EEAFENAYKLSDDKEAQLK 587
A S ++ L+E +E + +E + +L++ ++DL ++ +N ++L K A +
Sbjct: 1484 KALSLARALEEALE----AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQ 1539
Query: 588 QENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISK-LEAQVKQVE 646
Q +M L ++D L TE+ L + +K + L+ + +Q E
Sbjct: 1540 QVEEMRTQL-----------EELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNE 1588
Query: 647 HENMLSLR 654
+ L ++
Sbjct: 1589 EKKRLLIK 1596
>gi|55749708 outer dense fiber of sperm tails 2-like isoform b [Homo
sapiens]
Length = 513
Score = 50.8 bits (120), Expect = 6e-06
Identities = 46/205 (22%), Positives = 92/205 (44%), Gaps = 15/205 (7%)
Query: 446 NLKEKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEA 505
N + H I + E +I ++K+++ I+ +ED K + C E
Sbjct: 151 NAWKSHYEKIVIEKTELEVQIETMKKQI----INLLEDLKKMEDHGKNSC-------EEI 199
Query: 506 TSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRL 565
+V ++E +N L +E L+ +A ++ + E++ K++ I K+++
Sbjct: 200 LRKVHSIEYENETLNLENTKLKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQV 259
Query: 566 QDLEEAFENAYKLSDD---KEAQL-KQENKMFQDLLGEYESLGKEHRRVKDALNTTENKL 621
Q L+EA E ++ K Q+ K +NK + + G+ ES KE RV D+L E +L
Sbjct: 260 QKLQEAAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRL 319
Query: 622 LDAYTQISDLKRMISKLEAQVKQVE 646
+ + K + E +++++
Sbjct: 320 HECQESLQCCKGKCADQEHTIRELQ 344
Score = 40.8 bits (94), Expect = 0.007
Identities = 45/214 (21%), Positives = 93/214 (43%), Gaps = 20/214 (9%)
Query: 463 ESEINSLKQKLEAKE-----ISGVEDWKITNQILVDRCGQLDSALHEATS-RVRTLENKN 516
ESE +LK+K+ KE +S + + N + +R Q +HE ++ E +N
Sbjct: 10 ESENTNLKKKVFEKEAHIQELSCLFQSEKANTLKANRFSQSVKVVHERLQIQIHKREAEN 69
Query: 517 NLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRL----KSRLQDLEEAF 572
+ L+ V L + + + S++ + M+ +S++K + + K RL A
Sbjct: 70 DKLKEYVKSLETKIAKWNLQSRMNKNEAIVMKEASRQKTVALKKASKVYKQRLDHFTGAI 129
Query: 573 ENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLK 632
E D+EA+L + YE + E ++ + T + ++++ + DLK
Sbjct: 130 EKLTSQIRDQEAKLSETISASNAWKSHYEKIVIEKTELEVQIETMKKQIINL---LEDLK 186
Query: 633 RM-------ISKLEAQVKQVEHENMLSLRHNSRI 659
+M ++ +V +E+EN N+++
Sbjct: 187 KMEDHGKNSCEEILRKVHSIEYENETLNLENTKL 220
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,908,277
Number of Sequences: 37866
Number of extensions: 1920618
Number of successful extensions: 9557
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 144
Number of HSP's successfully gapped in prelim test: 647
Number of HSP's that attempted gapping in prelim test: 7049
Number of HSP's gapped (non-prelim): 2611
length of query: 1031
length of database: 18,247,518
effective HSP length: 112
effective length of query: 919
effective length of database: 14,006,526
effective search space: 12871997394
effective search space used: 12871997394
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.