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Search of human proteins with 34878787
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34878787 ring finger protein 25 [Homo sapiens]
(459 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34878787 ring finger protein 25 [Homo sapiens] 954 0.0
gi|65287717 eukaryotic translation initiation factor 2 alpha kin... 60 4e-09
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 55 2e-07
gi|50345997 E1A binding protein p300 [Homo sapiens] 51 2e-06
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 49 7e-06
gi|55953123 RWD domain containing 1 isoform a [Homo sapiens] 49 1e-05
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 49 1e-05
gi|160707881 formin 2 [Homo sapiens] 48 2e-05
gi|93277115 ataxin 7-like 2 [Homo sapiens] 48 2e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 47 4e-05
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 46 8e-05
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 45 1e-04
gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens] 45 1e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 45 1e-04
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 45 1e-04
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 44 2e-04
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 44 2e-04
gi|18641360 collectin sub-family member 12 [Homo sapiens] 44 3e-04
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 44 4e-04
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 44 4e-04
gi|150170670 piccolo isoform 2 [Homo sapiens] 44 4e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 44 4e-04
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 43 5e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni... 43 5e-04
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 43 7e-04
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 43 7e-04
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 43 7e-04
gi|19924099 synapsin I isoform Ia [Homo sapiens] 43 7e-04
gi|19924097 synapsin I isoform Ib [Homo sapiens] 43 7e-04
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 43 7e-04
>gi|34878787 ring finger protein 25 [Homo sapiens]
Length = 459
Score = 954 bits (2465), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MAASASAAAGEEDWVLPSEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQ 60
MAASASAAAGEEDWVLPSEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQ
Sbjct: 1 MAASASAAAGEEDWVLPSEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQ 60
Query: 61 YVCFTLVLQVPAEYPHEVPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEK 120
YVCFTLVLQVPAEYPHEVPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEK
Sbjct: 61 YVCFTLVLQVPAEYPHEVPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEK 120
Query: 121 GKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQ 180
GKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQ
Sbjct: 121 GKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQ 180
Query: 181 EQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEERKR 240
EQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEERKR
Sbjct: 181 EQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEERKR 240
Query: 241 LYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAV 300
LYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAV
Sbjct: 241 LYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAV 300
Query: 301 QSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGEC 360
QSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGEC
Sbjct: 301 QSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGEC 360
Query: 361 HAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRW 420
HAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRW
Sbjct: 361 HAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRW 420
Query: 421 ERSKGRTPGSSYPRLPRGQGAYRPGTRRESLGLESKDGS 459
ERSKGRTPGSSYPRLPRGQGAYRPGTRRESLGLESKDGS
Sbjct: 421 ERSKGRTPGSSYPRLPRGQGAYRPGTRRESLGLESKDGS 459
>gi|65287717 eukaryotic translation initiation factor 2 alpha kinase
4 [Homo sapiens]
Length = 1649
Score = 60.1 bits (144), Expect = 4e-09
Identities = 45/170 (26%), Positives = 80/170 (47%), Gaps = 25/170 (14%)
Query: 19 EVEVLESIYLDELQVIKGNGR---TSPWEIYITLHPATAEDQDSQYVCFTLVLQVPAEYP 75
E++ LE+IY + Q ++ + P EI + L+P ++ YV L ++ P YP
Sbjct: 26 ELQALEAIYGADFQDLRPDACGPVKEPPEINLVLYPQGLTGEEV-YVKVDLRVKCPPTYP 84
Query: 76 HEVPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEKGKEILTDNNIPHGQC 135
VP+I ++N +GLS+E ++ + L +AK G M++EL + L+++N P +
Sbjct: 85 DVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGEVMIFELAYHVQSFLSEHNKPPPKS 144
Query: 136 VICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQEQERQ 185
FH L R Q +Q L +++EQE++
Sbjct: 145 ---------------------FHEEMLERRAQEEQQRLLEAKRKEEQEQR 173
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 54.7 bits (130), Expect = 2e-07
Identities = 42/104 (40%), Positives = 51/104 (49%), Gaps = 23/104 (22%)
Query: 320 PGTRSNQQRLGETQKAML--DPPKPSRGPWRQPERRHPKGGEC-HAPKGTRDTQEL---- 372
PG R NQ G + M+ PP+ RGP HP GG H P+ R QE+
Sbjct: 788 PGPRENQ---GPAPQGMIMGHPPQEMRGP-------HPPGGLLGHGPQEMRGPQEIRGMQ 837
Query: 373 -PPPEGP-LKEPMDLKPEPHSQGVEGPPQ-EKGP---GSWQGPP 410
PPP+G L P +L+ P SQ +GPPQ GP G QGPP
Sbjct: 838 GPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPP 881
Score = 42.0 bits (97), Expect = 0.001
Identities = 55/257 (21%), Positives = 90/257 (35%), Gaps = 33/257 (12%)
Query: 177 GQEQEQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQE 236
G E+ ++ QK V P+ P + A ++ P E+ E ++ +E
Sbjct: 477 GMEEVMQKDQKKVPQKKVPYAKPI---PAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEE 533
Query: 237 ERKRLYQRQQERGGI----------IDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQP 286
++K + +QE + + +E + +Q PP+ P G P
Sbjct: 534 KKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGP 593
Query: 287 PSTLAAELSTS------PAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPP 340
S + P + + PP P + PG + G P
Sbjct: 594 MSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQF----RPPGPQGQMGPQGPPLHQGGGGP 649
Query: 341 KPSRGPW--RQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHS-----QG 393
+ GP + P + P+ + H P+G Q P P GPL P+ S G
Sbjct: 650 QGFMGPQGPQGPPQGLPRPQDMHGPQGM---QRHPGPHGPLGPQGPPGPQGSSGPQGHMG 706
Query: 394 VEGPPQEKGPGSWQGPP 410
+GPP +G QGPP
Sbjct: 707 PQGPPGPQGHIGPQGPP 723
Score = 36.2 bits (82), Expect = 0.064
Identities = 35/130 (26%), Positives = 51/130 (39%), Gaps = 18/130 (13%)
Query: 327 QRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRD---TQELPP--------- 374
+RL + Q + PP S P P+ +G P+G + +Q++P
Sbjct: 562 ERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPG 621
Query: 375 PEGPLKEP-----MDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTR-DCVRWERSKGRTP 428
P+G + P M + P QG GP GP QGPP R + + R P
Sbjct: 622 PQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHP 681
Query: 429 GSSYPRLPRG 438
G P P+G
Sbjct: 682 GPHGPLGPQG 691
Score = 33.1 bits (74), Expect = 0.54
Identities = 25/89 (28%), Positives = 35/89 (39%), Gaps = 19/89 (21%)
Query: 340 PKPSRGPWRQPERRHPKGGECH-APKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPP 398
P+ GP + P G + H P+G TQ + P GP ++ PH G++G P
Sbjct: 707 PQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGP----RGMQGPPHPHGIQGGP 762
Query: 399 QEKG--------------PGSWQGPPPRR 413
+G P QGPP R
Sbjct: 763 GSQGIQGPVSQGPLMGLNPRGMQGPPGPR 791
Score = 31.6 bits (70), Expect = 1.6
Identities = 51/221 (23%), Positives = 76/221 (34%), Gaps = 38/221 (17%)
Query: 265 LQQPPAPAE-----PESAV-----DVSKGSQPPSTLAA----ELSTSPAVQSTLPPPLPV 310
+Q PP P E P+ + +G PP L E+ ++ PP
Sbjct: 784 MQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQG 843
Query: 311 ATQHICEKIPGTRSNQQRLGETQKAMLDPPKPS-RGPWRQPERRHPKGGECHAPKGTRDT 369
+ +++ G +Q + G Q ++ PP+ +GP +++P G H +G
Sbjct: 844 SMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGP-HPSQGPIPF 902
Query: 370 QELPPP------------EGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGP-------P 410
Q+ P EG P L P QG +G PG GP P
Sbjct: 903 QQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGP 962
Query: 411 PRRTRDCV---RWERSKGRTPGSSYPRLPRGQGAYRPGTRR 448
P + R E+S G G GQ P RR
Sbjct: 963 PNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRR 1003
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 51.2 bits (121), Expect = 2e-06
Identities = 59/243 (24%), Positives = 88/243 (36%), Gaps = 16/243 (6%)
Query: 178 QEQEQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEE 237
Q+ ++ QH ++ CP+C++ + K E + P+ + LRQQ+
Sbjct: 1759 QKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQL 1818
Query: 238 RKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQP--PSTLAAELS 295
+ RL Q Q R + A R + QQ P+ + G QP P T
Sbjct: 1819 QHRLQQAQMLRRRM----ASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQ 1874
Query: 296 TSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGP------WRQ 349
P +++PP LP TQ G + Q T PP P P +
Sbjct: 1875 PQPTPPNSMPPYLP-RTQAAGPVSQGKAAGQV-TPPTPPQTAQPPLPGPPPAAVEMAMQI 1932
Query: 350 PERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQE-KGPGSWQG 408
+ H R Q PP P+ PM + P P ++G G + GP Q
Sbjct: 1933 QRAAETQRQMAHVQIFQRPIQHQMPPMTPM-APMGMNPPPMTRGPSGHLEPGMGPTGMQQ 1991
Query: 409 PPP 411
PP
Sbjct: 1992 QPP 1994
Score = 35.4 bits (80), Expect = 0.11
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 32/185 (17%)
Query: 265 LQQP-------PAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICE 317
+QQP P P ++V+ PS+ A +S + S+ P P+
Sbjct: 755 MQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMP----- 809
Query: 318 KIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRH--PKGGECHAPKGTRDTQELPPP 375
PG++ + + + L PS P R P H P G P T +P
Sbjct: 810 --PGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATT-----IP-- 860
Query: 376 EGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYP-R 434
P+ P + P P SQ + PP+ Q P P T+ + + S P + P +
Sbjct: 861 -APVPTPPAMPPGPQSQALHPPPR-------QTPTPPTTQLPQQVQPSLPAAPSADQPQQ 912
Query: 435 LPRGQ 439
PR Q
Sbjct: 913 QPRSQ 917
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 49.3 bits (116), Expect = 7e-06
Identities = 51/175 (29%), Positives = 66/175 (37%), Gaps = 48/175 (27%)
Query: 268 PPAPAEPESAV----DVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTR 323
PP P +P+ + S+G PP QS PPP P + P +
Sbjct: 51 PPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPER-----PPPQ 105
Query: 324 SNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGG-ECHAPKGTRDTQELPPPEGPLKE- 381
Q G PP P + PER P+GG + H P E PPP+G +
Sbjct: 106 GGNQSQGT-------PPPPGK-----PERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQ 153
Query: 382 ---PMDLKPE--PHSQG------------VEGPPQEKG--------PGSWQGPPP 411
P KPE P +G +GPPQ++G PG QGPPP
Sbjct: 154 GPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPP 208
Score = 43.9 bits (102), Expect = 3e-04
Identities = 41/148 (27%), Positives = 54/148 (36%), Gaps = 15/148 (10%)
Query: 268 PPAPAEPE----SAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTR 323
PP P +PE + S+G+ PP QS PPP P E+ P
Sbjct: 93 PPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKP----ERPPPQG 148
Query: 324 SNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPM 383
NQ + + P P G + R P G P+ + + PPP G + P
Sbjct: 149 GNQSQGPPPHPGKPEGPPPQEGN-KSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGP- 206
Query: 384 DLKPEPHSQGVEGPPQEKGPGSWQGPPP 411
P + G PQ G QGPPP
Sbjct: 207 -----PPAGGNPQQPQAPPAGKPQGPPP 229
Score = 41.2 bits (95), Expect = 0.002
Identities = 43/168 (25%), Positives = 55/168 (32%), Gaps = 35/168 (20%)
Query: 301 QSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERR------- 353
Q PPP P Q P + Q G PP P + R P+
Sbjct: 46 QPQRPPPPPGKPQG-----PPPQGGNQSQGP-------PPPPGKPEGRPPQGGNQSQGPP 93
Query: 354 -HPKGGECHAPKGTRDTQELPPPEGPLKEP------MDLKPEPHSQGVEGPPQEKG---- 402
HP E P+G +Q PPP G + P +P P E PP + G
Sbjct: 94 PHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQ 153
Query: 403 -----PGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQGAYRPG 445
PG +GPPP+ G+ G + QG PG
Sbjct: 154 GPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPG 201
Score = 34.7 bits (78), Expect = 0.19
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 20/92 (21%)
Query: 349 QPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQG 408
+PE R P+GG Q PPP G +P P+ +Q +GPP PG +G
Sbjct: 35 KPEGRRPQGGN--------QPQRPPPPPG---KPQGPPPQGGNQS-QGPPPP--PGKPEG 80
Query: 409 PPPRRTRDCVRWERSKGRTPGSSYPRLPRGQG 440
PP+ +S+G P P P QG
Sbjct: 81 RPPQ------GGNQSQGPPPHPGKPERPPPQG 106
>gi|55953123 RWD domain containing 1 isoform a [Homo sapiens]
Length = 243
Score = 48.9 bits (115), Expect = 1e-05
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 18 SEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQYVCFTLVLQVPAEYPHE 77
+E+E LESIY D V+ N P IT+ E+ ++ V TL +YP E
Sbjct: 10 NELEALESIYPDSFTVLSEN----PPSFTITVTSEAGENDET--VQTTLKFTYSEKYPDE 63
Query: 78 VPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEKGKEILTD 127
P I + L D + IL++L A+ LG M++ L+ +E L +
Sbjct: 64 APLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNE 113
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 48.5 bits (114), Expect = 1e-05
Identities = 54/195 (27%), Positives = 69/195 (35%), Gaps = 24/195 (12%)
Query: 268 PPAPAEPESAV----DVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTR 323
PP P +PE + S+G P QS PPP P E P
Sbjct: 114 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP----EGPPPQG 169
Query: 324 SNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPP----PEGPL 379
NQ + + P P G Q P E P+G +Q PP PEGP
Sbjct: 170 GNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 229
Query: 380 KEPMDLK--PEPHSQGVEGPPQEKG--------PGSWQGPPPRRTRDCVRWERSKGRTPG 429
+ + P PH +GPP ++G PG QGPPP G+ G
Sbjct: 230 SQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQG 289
Query: 430 SSYPRLPRGQGAYRP 444
P P+G +RP
Sbjct: 290 PPPP--PQGGRPHRP 302
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/150 (30%), Positives = 55/150 (36%), Gaps = 17/150 (11%)
Query: 301 QSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGEC 360
Q T PPP E P NQ + + + P P G Q P E
Sbjct: 48 QRTPPPPGKP------EGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG 101
Query: 361 HAPKGTRDTQELPP----PEGPLKE--PMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRT 414
P+G +Q PP PEGP + P P EGPP + G S QGPPPR
Sbjct: 102 QPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQS-QGPPPRPG 160
Query: 415 R----DCVRWERSKGRTPGSSYPRLPRGQG 440
+ +S+G P P P QG
Sbjct: 161 KPEGPPPQGGNQSQGPPPHPGKPEGPPPQG 190
Score = 38.1 bits (87), Expect = 0.017
Identities = 33/102 (32%), Positives = 39/102 (38%), Gaps = 19/102 (18%)
Query: 349 QPERRHPKGGECHAPKGTRDTQELPPPEG------PLKEPMDLKPEPHSQGVEGPPQEKG 402
+PE R P+GG Q PPP G P P P EGPP + G
Sbjct: 35 KPEGRRPQGGN--------QPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGG 86
Query: 403 PGSWQGPPPR----RTRDCVRWERSKGRTPGSSYPRLPRGQG 440
S QGPPPR + +S+G P P P QG
Sbjct: 87 NQS-QGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQG 127
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 48.1 bits (113), Expect = 2e-05
Identities = 68/250 (27%), Positives = 93/250 (37%), Gaps = 37/250 (14%)
Query: 173 LKAQGQEQEQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAP-EPQQPMELYQPSAES 231
L+A E+++ R H + K++ Q E V L + P P P P AES
Sbjct: 723 LEALRLEEKEVRHHRILEAKSI--QTSPTEEGGVLTLPPVDGLPGRPPCP-----PGAES 775
Query: 232 LRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLA 291
Q + + R + L++ + IS Q PP P+ SA GSQPP +++
Sbjct: 776 GPQTKFCSEISLIVSPRRISVQLDSHQPTQSIS-QPPPPPSLLWSAGQGQPGSQPPHSIS 834
Query: 292 AELSTS--PAVQSTL--------PPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPK 341
E TS +V S PPPLP T S+ G PP
Sbjct: 835 TEFQTSHEHSVSSAFKNSCNIPSPPPLPC-----------TESSSSMPGLGMVPPPPPPL 883
Query: 342 PSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEK 401
P P P+ P + T+ LPPP PL + P P G P
Sbjct: 884 PGMTVPTLPSTAIPQ------PPPLQGTEMLPPPPPPL-PGAGIPPPPPLPGAGILPLPP 936
Query: 402 GPGSWQGPPP 411
PG+ PPP
Sbjct: 937 LPGAGIPPPP 946
Score = 35.4 bits (80), Expect = 0.11
Identities = 41/144 (28%), Positives = 48/144 (33%), Gaps = 30/144 (20%)
Query: 268 PPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQ 327
PP P P +A+ PP L P LPPPLP A +PG
Sbjct: 943 PPPPPLPGAAIP------PPPPL-------PGAGIPLPPPLPGAGIPPPPPLPG------ 983
Query: 328 RLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKP 387
A + PP P G P P G P +PPP P + P
Sbjct: 984 -------AGIPPPPPLPGAGIPPPPPLPGAGI--PPPPPLPGAGIPPP--PPLPGAGIPP 1032
Query: 388 EPHSQGVEGPPQEKGPGSWQGPPP 411
P G PP PG+ PPP
Sbjct: 1033 PPPLPGAGIPPPPPLPGAGIPPPP 1056
Score = 34.7 bits (78), Expect = 0.19
Identities = 45/152 (29%), Positives = 52/152 (34%), Gaps = 35/152 (23%)
Query: 268 PPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQ 327
PP P P + G PP L P V PPPLP A +PG
Sbjct: 1086 PPPPPLPGA------GIPPPPPL-------PGVGIPPPPPLPGAGIPPPPPLPG------ 1126
Query: 328 RLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPK----GTRDTQELP----PPEGPL 379
A + PP P G P P+ G P G LP PP PL
Sbjct: 1127 -------AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1179
Query: 380 KEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPP 411
+ + P P GV PP PG+ PPP
Sbjct: 1180 PG-VGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1210
Score = 33.1 bits (74), Expect = 0.54
Identities = 37/144 (25%), Positives = 47/144 (32%), Gaps = 19/144 (13%)
Query: 268 PPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQ 327
PP P P + + PP A L P + +PPP P+ I P +
Sbjct: 910 PPPPPLPGAGIP----PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIP 965
Query: 328 RLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKP 387
A + PP P G P P G +PPP P + P
Sbjct: 966 LPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-------------IPPP--PPLPGAGIPP 1010
Query: 388 EPHSQGVEGPPQEKGPGSWQGPPP 411
P G PP PG+ PPP
Sbjct: 1011 PPPLPGAGIPPPPPLPGAGIPPPP 1034
Score = 32.7 bits (73), Expect = 0.71
Identities = 48/205 (23%), Positives = 76/205 (37%), Gaps = 22/205 (10%)
Query: 219 QQPMELYQPSAESLR---QQEERKRLYQRQQERGGIIDLEAERNRYFISLQQ-------- 267
QQ + L Q + L+ QQ+++++ Q +E + + F+ L +
Sbjct: 200 QQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGG 259
Query: 268 -PPAPAEPESAVDVSKGSQPPSTLAAELST--SPAVQSTLP----PPLPVATQHICEKIP 320
AP P++ +S S P +LAAE P LP P LP A +
Sbjct: 260 AGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPS 319
Query: 321 GTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLK 380
T G ++A P RG E E AP+G+ + P
Sbjct: 320 STAFPFPEAGPGEEAA---GAPVRGAGDTDEEGEEDAFE-DAPRGSPGEEWAPEVGEDAP 375
Query: 381 EPMDLKPEPHSQGVEGPPQEKGPGS 405
+ + +PE +QG + P PGS
Sbjct: 376 QRLGEEPEEEAQGPDAPAAASLPGS 400
Score = 32.3 bits (72), Expect = 0.92
Identities = 37/145 (25%), Positives = 49/145 (33%), Gaps = 10/145 (6%)
Query: 268 PPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQST-LPPPLPVATQHICEKIPGTRSNQ 326
PP P P + + + PP A + P + +PPP P+ I P +
Sbjct: 954 PPPPPLPGAGIPL-----PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1008
Query: 327 QRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLK 386
A + PP P G P P G P +PPP P +
Sbjct: 1009 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI--PPPPPLPGAGIPPP--PPLPGAGIP 1064
Query: 387 PEPHSQGVEGPPQEKGPGSWQGPPP 411
P P G PP PG+ PPP
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPP 1089
Score = 32.0 bits (71), Expect = 1.2
Identities = 39/147 (26%), Positives = 48/147 (32%), Gaps = 25/147 (17%)
Query: 268 PPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQST---LPPPLPVATQHICEKIPGTRS 324
PP P P + + PP A + P + PPPLP A +PG
Sbjct: 976 PPPPPLPGAGIP-----PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG--- 1027
Query: 325 NQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMD 384
A + PP P G P P G P +PPP P
Sbjct: 1028 ----------AGIPPPPPLPGAGIPPPPPLPGAGI--PPPPPLPGAGIPPP--PPLPGAG 1073
Query: 385 LKPEPHSQGVEGPPQEKGPGSWQGPPP 411
+ P P G PP PG+ PPP
Sbjct: 1074 IPPPPPLPGAGIPPPPPLPGAGIPPPP 1100
Score = 30.8 bits (68), Expect = 2.7
Identities = 39/147 (26%), Positives = 47/147 (31%), Gaps = 25/147 (17%)
Query: 268 PPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQST---LPPPLPVATQHICEKIPGTRS 324
PP P P + + PP A + P + PPPLP A +PG
Sbjct: 987 PPPPPLPGAGIP-----PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG--- 1038
Query: 325 NQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMD 384
A + PP P G P P G P +PPP P
Sbjct: 1039 ----------AGIPPPPPLPGAGIPPPPPLPGAGI--PPPPPLPGAGIPPP--PPLPGAG 1084
Query: 385 LKPEPHSQGVEGPPQEKGPGSWQGPPP 411
+ P P G PP PG PPP
Sbjct: 1085 IPPPPPLPGAGIPPPPPLPGVGIPPPP 1111
>gi|93277115 ataxin 7-like 2 [Homo sapiens]
Length = 722
Score = 47.8 bits (112), Expect = 2e-05
Identities = 41/135 (30%), Positives = 56/135 (41%), Gaps = 8/135 (5%)
Query: 305 PPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPK 364
PPP P ++Q C + G + G T+ + + + SR QP + K C
Sbjct: 116 PPPAPASSQK-CHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQPGG 174
Query: 365 GTRDTQELPPPEGPLKEP-----MDLKP-EPHSQGVEGPPQEKGPGSWQGPPPRRTRDCV 418
T+D+ PP P KEP +++ P E S EG P EK P S PP+ R
Sbjct: 175 LTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEP-SGTRLPPKTHRKMA 233
Query: 419 RWERSKGRTPGSSYP 433
R E R G P
Sbjct: 234 RKECDLNRQCGVINP 248
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 47.0 bits (110), Expect = 4e-05
Identities = 35/120 (29%), Positives = 47/120 (39%), Gaps = 14/120 (11%)
Query: 269 PAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQR 328
P P P + G+ PP+ ++ + T+P Q+ PPP P A + PG +
Sbjct: 149 PTPTPPPAVTSAPPGAPPPTPPSSGVPTTPP-QAGGPPPPPAA---VPGPGPGPKQGPGP 204
Query: 329 LGETQKAMLDPPKPSRGPWRQPERRHPK----------GGECHAPKGTRDTQELPPPEGP 378
G M PKP GP HPK GG H P + + PPP GP
Sbjct: 205 GGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGP 264
Score = 40.4 bits (93), Expect = 0.003
Identities = 44/167 (26%), Positives = 58/167 (34%), Gaps = 23/167 (13%)
Query: 266 QQPPAPAEPESAVDVSK--------GSQPPSTLAAELSTSP---AVQSTLPPPLPVATQH 314
QQPP P + S V++ GS PP++ +A +T P A + P P P
Sbjct: 97 QQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPA 156
Query: 315 ICEKIP----------GTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPK 364
+ P G + + G P P GP + P PKGG+
Sbjct: 157 VTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGP 216
Query: 365 GTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPP 411
L P G K P EP PP + QGPPP
Sbjct: 217 KPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQ--QHHQGPPP 261
Score = 30.0 bits (66), Expect = 4.6
Identities = 19/74 (25%), Positives = 27/74 (36%), Gaps = 1/74 (1%)
Query: 373 PPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSY 432
PPP ++P +P P PP P Q PPP +D + ++G P
Sbjct: 63 PPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPP-PPQDSSKPVVAQGPGPAPGV 121
Query: 433 PRLPRGQGAYRPGT 446
P + P T
Sbjct: 122 GSAPPASSSAPPAT 135
Score = 29.3 bits (64), Expect = 7.8
Identities = 29/121 (23%), Positives = 38/121 (31%), Gaps = 22/121 (18%)
Query: 301 QSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGEC 360
QS PP+P H QQ+ Q PP P QP ++
Sbjct: 53 QSGPKPPIPPPPPH---------QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQ------ 97
Query: 361 HAPKGTRDTQELPPPEGP-------LKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRR 413
P +D+ + +GP P P + G P GPG PPP
Sbjct: 98 QPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAV 157
Query: 414 T 414
T
Sbjct: 158 T 158
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 45.8 bits (107), Expect = 8e-05
Identities = 52/185 (28%), Positives = 66/185 (35%), Gaps = 26/185 (14%)
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSN 325
Q PP P +P+ G P + S SP + PPP PG
Sbjct: 151 QGPPPPGKPQ-------GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 203
Query: 326 QQRLGETQKAMLDPPKPSRGPWRQPER-----RHPKGG-ECHAPKGTRDTQELPPPEGPL 379
G + PP +GP Q + R P G + P+G Q PPP G
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKP 263
Query: 380 KEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQ 439
+ P P +GPP PG QGPPP+ RS PG P+ P Q
Sbjct: 264 QGP----PPQGGNKPQGPPP---PGKPQGPPPQGGSK----SRSSRSPPGK--PQGPPPQ 310
Query: 440 GAYRP 444
G +P
Sbjct: 311 GGNQP 315
Score = 43.1 bits (100), Expect = 5e-04
Identities = 47/182 (25%), Positives = 63/182 (34%), Gaps = 21/182 (11%)
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAV---QSTLPPPLPVATQHICEKIPGT 322
Q PP P +P+ S+ P + + P Q PPP P Q P
Sbjct: 90 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG-----PPP 144
Query: 323 RSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEP 382
+ + G P P + R P + P+G Q PPP G + P
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 204
Query: 383 MDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQGAY 442
P +GPP PG QGPPP+ +S PG P+ P QG
Sbjct: 205 ----PPQGGNKPQGPPP---PGKPQGPPPQGDNK----SQSARSPPGK--PQGPPPQGGN 251
Query: 443 RP 444
+P
Sbjct: 252 QP 253
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/153 (26%), Positives = 54/153 (35%), Gaps = 20/153 (13%)
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSN 325
Q PP P +P+ G P ++ + SP + PPP PG
Sbjct: 213 QGPPPPGKPQ-------GPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 265
Query: 326 QQRLGETQKAMLDPPKPSRGPWRQ------PERRHPKGGECHAPKGTRDTQELPPPEGPL 379
G + PP +GP Q R P + P+G Q PPP G
Sbjct: 266 PPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 325
Query: 380 KEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPR 412
+ P P +GPP PG QGPPP+
Sbjct: 326 QGP----PPQGGNKPQGPPP---PGKPQGPPPQ 351
Score = 40.0 bits (92), Expect = 0.004
Identities = 46/177 (25%), Positives = 60/177 (33%), Gaps = 19/177 (10%)
Query: 268 PPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQ 327
PP P +P+ PP P + PPP + PG
Sbjct: 257 PPPPGKPQGP--------PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP 308
Query: 328 RLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKP 387
G Q PP P P P P+GG + PPP+G K P
Sbjct: 309 PQGGNQPQ--GPPPPPGKPQGPP----PQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP 362
Query: 388 EPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQGAYRP 444
QG PPQ++G + QGPPP + + + P PR P+G RP
Sbjct: 363 PGKPQG---PPQQEG-NNPQGPPPPAGGNPQQPQAPPAGQP-QGPPRPPQGGRPSRP 414
Score = 38.5 bits (88), Expect = 0.013
Identities = 39/134 (29%), Positives = 53/134 (39%), Gaps = 19/134 (14%)
Query: 311 ATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQ 370
+ Q++ E + S G Q A +GP P + P+G P+G Q
Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGK--PQGPP---PQGGNQPQ 69
Query: 371 ELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGS 430
PPP G + P P +GPP PG QGPPP+ + RS PG
Sbjct: 70 GPPPPPGKPQGP----PPQGGNKPQGPPP---PGKPQGPPPQGDK-----SRSPRSPPGK 117
Query: 431 SYPRLPRGQGAYRP 444
P+ P QG +P
Sbjct: 118 --PQGPPPQGGNQP 129
Score = 33.5 bits (75), Expect = 0.41
Identities = 36/147 (24%), Positives = 46/147 (31%), Gaps = 19/147 (12%)
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSN 325
Q PP P +P+ G P + S SP + PPP PG
Sbjct: 275 QGPPPPGKPQ-------GPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 327
Query: 326 QQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGT---------RDTQELPPPE 376
G + PP +GP P + K +P G + Q PPP
Sbjct: 328 PPPQGGNKPQGPPPPGKPQGP---PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPA 384
Query: 377 GPLKEPMDLKPEPHSQGVEGPPQEKGP 403
G + P QG PPQ P
Sbjct: 385 GGNPQQPQAPPAGQPQGPPRPPQGGRP 411
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 45.4 bits (106), Expect = 1e-04
Identities = 54/283 (19%), Positives = 102/283 (36%), Gaps = 32/283 (11%)
Query: 160 HCLARYIQHMEQELKAQGQ-----EQEQERQHATTKQKAVGVQCPVCREPL--------- 205
H + IQ +Q+L+ Q +Q+Q++Q +Q+A+ Q P+ + P+
Sbjct: 225 HQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQ 284
Query: 206 --------VYDLASLKAAPEPQQPMELYQPSAESLRQQEERKRLYQRQQERGGIIDLEAE 257
++ + P+PQQP ++ Q + + + Q Q G ++ +
Sbjct: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP 344
Query: 258 RN--RYFISLQQPPAPAEPESAVDVSKGSQPPSTLA--AELSTSPAVQSTLP-----PPL 308
R + +QQPP + + + +Q +A ++ T Q + PP
Sbjct: 345 LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPT 404
Query: 309 PVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRD 368
+ IP R ++ ++ ML P P + + P+ P P
Sbjct: 405 TAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQV-QTPQSMPPPPQPSPQPGQPSS 463
Query: 369 TQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPP 411
GP P P P Q + P + P ++ P P
Sbjct: 464 QPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSP 506
>gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens]
Length = 340
Score = 45.4 bits (106), Expect = 1e-04
Identities = 58/225 (25%), Positives = 87/225 (38%), Gaps = 38/225 (16%)
Query: 267 QPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQS--------TLPP----PLPVATQH 314
QP AP + S P + LA E + +PA S +L P + +
Sbjct: 44 QPEAPQPGPNTTAAPVDSGPKAGLAPETTETPAGASETAQATDLSLSPGGESKANCSPED 103
Query: 315 ICEKIPGTRSNQQRLGETQKAMLD---PPKPSRGPWRQPERRHPKGGECHAPKGTRD--- 368
C++ + Q + L+ PP+P+ P QP+ P+ PK
Sbjct: 104 PCQETVSKPEVSKEATADQGSRLESAAPPEPAPEPAPQPD---PRPDSQPTPKPALQPEL 160
Query: 369 -TQELPPPE------GPLKEPMDLKPEPHSQGVEGP-------PQEKGPGSWQGPPPRRT 414
TQE P PE G +E + P G EGP P +K P + G PPR
Sbjct: 161 PTQEDPTPEILSESVGEKQENGAVVPLQAGDGEEGPAPEPHSPPSKKSPPA-NGAPPRVL 219
Query: 415 RDCVRWERSKGRTPGSSYPRLPRGQGAYRPGTRRESLGLESKDGS 459
+ V E + R S +P PRG + P ++ G+E +G+
Sbjct: 220 QQLV--EEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGT 262
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 45.1 bits (105), Expect = 1e-04
Identities = 66/286 (23%), Positives = 119/286 (41%), Gaps = 50/286 (17%)
Query: 166 IQHMEQELKAQGQEQEQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELY 225
+Q ++Q+ + Q Q+Q Q++Q +Q Q + ++ L + + QQ ++
Sbjct: 3897 LQQLQQQQQLQQQQQLQQQQQQQLQQ-----QQQLQQQQLQQQQQQQQLQQQQQQQLQQQ 3951
Query: 226 QPSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQ---------PPAPAEPES 276
Q + +QQ++++ Q+QQ++ G+++ ++R +S QQ P PA+P
Sbjct: 3952 QQQLQQQQQQQQQQFQQQQQQQQMGLLN----QSRTLLSPQQQQQQQVALGPGMPAKPLQ 4007
Query: 277 AVDVSKGSQPPSTLAA---ELSTSPAVQSTLPP--------PLPVATQHICEKIPGTRSN 325
S G+ P+ L + + PAV S PL + T
Sbjct: 4008 HFS-SPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVK 4066
Query: 326 QQRLGETQKAMLDP---PKPS----RGPWRQPERR-------HPKGGECHAPKGTRDTQE 371
G++Q ++ P P+PS + P R P ++ H GG H G+ + E
Sbjct: 4067 PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSE 4126
Query: 372 LPPPEGPLKEP-MDLKPEPHS--QGVEGPPQ---EKGPGSWQGPPP 411
L +P + L +P S Q + GP Q E+ + GP P
Sbjct: 4127 ASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQP 4172
Score = 40.8 bits (94), Expect = 0.003
Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 24/97 (24%)
Query: 339 PPKPSRGPWRQPERRH------PKGG-------------ECHA-PKGTRDTQELPPPEGP 378
PP+P P +P+ + PKGG +C A P G Q P E P
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433
Query: 379 LKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTR 415
L E M L P P + PP+E S PPP +R
Sbjct: 434 LNEEMPLLPPPEESPLSPPPEE----SPTSPPPEASR 466
Score = 35.0 bits (79), Expect = 0.14
Identities = 45/178 (25%), Positives = 61/178 (34%), Gaps = 26/178 (14%)
Query: 265 LQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRS 324
L++ P PE S S PP + SP +S L PP E+ P + +
Sbjct: 489 LEESPLSPPPEE----SPLSPPPESSPF----SPLEESPLSPP---------EESPPSPA 531
Query: 325 NQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMD 384
+ L +A P P P P A + + +E P P + PM
Sbjct: 532 LETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS 591
Query: 385 LKPE------PHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLP 436
PE P + PP E+ P S PPP +R E S P P P
Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLS---PPPEASRLSPPPEDSPMSPPPEESPMSP 646
Score = 35.0 bits (79), Expect = 0.14
Identities = 45/184 (24%), Positives = 66/184 (35%), Gaps = 16/184 (8%)
Query: 264 SLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTL--PPPLPVATQHICEKIPG 321
+L+ P +P S + P S EL TSP +++ PPP E+ P
Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPM 590
Query: 322 TRSNQ--QRLGETQKAMLDPPKPSRGPWRQP---ERRHPKGGECHAPKGTRDTQELPPPE 376
+ + + +++ L PP P P P R P + ++ PPPE
Sbjct: 591 SPPPEASRLFPPFEESPLSPP-PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPE 649
Query: 377 GPLKEPMD----LKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSY 432
P+ L P P + PP+E S PPP +R E S P
Sbjct: 650 VSRLSPLPVVSRLSPPPEESPLSPPPEE----SPTSPPPEASRLSPPPEDSPTSPPPEDS 705
Query: 433 PRLP 436
P P
Sbjct: 706 PASP 709
Score = 34.3 bits (77), Expect = 0.24
Identities = 60/257 (23%), Positives = 86/257 (33%), Gaps = 52/257 (20%)
Query: 185 QHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQ-----------PSAESLR 233
Q + Q +G Q P+ P+ + P+P +P + Q P+ LR
Sbjct: 4144 QPGSMTQNLLGPQQPMLERPMQNN-----TGPQPPKPGPVLQSGQGLPGVGIMPTVGQLR 4198
Query: 234 QQ--------EERKRLYQRQQERGGIIDLEAERNRYFISLQQPP--APAEPESAVDVSKG 283
Q + + L +QQ++ + ++ + + Q PP P S + G
Sbjct: 4199 AQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLG 4258
Query: 284 SQP-------PST-LAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKA 335
QP P T EL P Q PP LP PG S LG
Sbjct: 4259 CQPQLGGFPGPQTGPLQELGAGPRPQG--PPRLPAP--------PGALSTGPVLGPVHPT 4308
Query: 336 MLDPPKPSRGPWRQPERRHPKGG---ECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQ 392
PP + P R + P E P T P P+GP EP + P +
Sbjct: 4309 --PPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT---PKPQGPTLEPPPGRVSPAAA 4363
Query: 393 GVEGPPQEKGPGSWQGP 409
+ KG G W P
Sbjct: 4364 QLADTLFSKGLGPWDPP 4380
Score = 34.3 bits (77), Expect = 0.24
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 263 ISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGT 322
+S P P+ P S + S S PP+ EL T P + +P PLP+A+ + P
Sbjct: 4906 LSAPPPEEPSPPPSPLAPSPAS-PPTEPLVELPTEPLAEPPVPSPLPLASSPESAR-PKP 4963
Query: 323 RSNQQRLGETQKAMLDPPK 341
R+ GE + PP+
Sbjct: 4964 RARPPEEGEDSR----PPR 4978
Score = 33.5 bits (75), Expect = 0.41
Identities = 51/207 (24%), Positives = 76/207 (36%), Gaps = 23/207 (11%)
Query: 215 APEPQQPMELYQPSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQPP-APAE 273
+P P++P QP L Q E L R +E + E E+ ++PP P +
Sbjct: 816 SPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE--SHLSPELEKPPLSPRPEKPPEEPGQ 873
Query: 274 PESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQ 333
+ ++ P + L PA+ PPL + E++P + S + L Q
Sbjct: 874 CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPL----SPLPEELPLSPSGEPSL-SPQ 928
Query: 334 KAMLDPPKPSRGP---WRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPM---DLKP 387
DP P P P P GE P G + + PE PL P+ + P
Sbjct: 929 LMPPDPLPPPLSPIITAAAPPALSPL-GELEYPFGAKGDSD---PESPLAAPILETPISP 984
Query: 388 EPHSQGVEGPP-----QEKGPGSWQGP 409
P + + P PGS GP
Sbjct: 985 PPEANCTDPEPVPPMILPPSPGSPVGP 1011
Score = 30.0 bits (66), Expect = 4.6
Identities = 42/178 (23%), Positives = 56/178 (31%), Gaps = 31/178 (17%)
Query: 267 QPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTL--PPPLPVATQHICEKIPGTRS 324
Q AP E + P S E TSP +++ PPP + + E + +R
Sbjct: 429 QLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRP 488
Query: 325 NQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMD 384
+++ L PP P P P P P E PL P +
Sbjct: 489 -------LEESPLSPP-PEESPLSPPPESSPFS---------------PLEESPLSPPEE 525
Query: 385 LKPEPHSQGVEGPPQEKGP------GSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLP 436
P P + PP E P S PPP E S+ P P P
Sbjct: 526 SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP 583
Score = 29.6 bits (65), Expect = 6.0
Identities = 36/144 (25%), Positives = 47/144 (32%), Gaps = 16/144 (11%)
Query: 263 ISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGT 322
+S PP P S + PP A+ LS P T PPP P
Sbjct: 659 VSRLSPPPEESPLSPPPEESPTSPPPE-ASRLSPPPEDSPTSPPPEDSPAS------PPP 711
Query: 323 RSNQQRLGETQKAMLD-PPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKE 381
+ L + +L P +P P + P+ E H + P E P
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLS 771
Query: 382 PMDLKP-------EPH-SQGVEGP 397
P +P EPH S EGP
Sbjct: 772 PQPEEPCLCAVPEEPHLSPQAEGP 795
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 45.1 bits (105), Expect = 1e-04
Identities = 49/197 (24%), Positives = 70/197 (35%), Gaps = 32/197 (16%)
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAV---QSTLPPPLPVATQHICEK---- 318
Q PP P +P+ S+ P + + P Q PPP P Q +
Sbjct: 69 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNR 128
Query: 319 -----IPGTRSNQQRLGETQKAMLDPPKPSRGP----WRQPERRHPKGGECHAP--KGTR 367
PG G+ ++ PP +GP QP+ P G+ P +G +
Sbjct: 129 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188
Query: 368 DTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRT 427
Q PPP P P QG + + PG QGPPP+ + +G
Sbjct: 189 KPQGPPPPGKP--------QGPPPQGDKSRSSQSPPGKPQGPPPQ------GGNQPQGPP 234
Query: 428 PGSSYPRLPRGQGAYRP 444
P P+ P QG +P
Sbjct: 235 PPPGKPQGPPPQGGNKP 251
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/202 (25%), Positives = 73/202 (36%), Gaps = 25/202 (12%)
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAV---QSTLPPPLPVATQHICEK---- 318
Q PP P +P+ S+ P + + P Q PPP P Q +
Sbjct: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189
Query: 319 -----IPGTRSNQQRLGETQKAMLDPPKPSRGP----WRQPERRHPKGGECHAP--KGTR 367
PG G+ ++ PP +GP QP+ P G+ P +G
Sbjct: 190 PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249
Query: 368 DTQELPPPEGPLKEPMDLKPEPHSQGV-----EGPPQEKGPGSWQGPPPRRTRDCVRWER 422
Q PPP P P + S +GPPQ++G + QGPPP + + +
Sbjct: 250 KPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG-NNPQGPPPPAGGNPQQPQA 308
Query: 423 SKGRTPGSSYPRLPRGQGAYRP 444
P PR P+G RP
Sbjct: 309 PPAGQP-QGPPRPPQGGRPSRP 329
Score = 36.6 bits (83), Expect = 0.049
Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 14/83 (16%)
Query: 362 APKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWE 421
+P+G Q PPP G + P P +GPP PG QGPPP+ +
Sbjct: 40 SPQGGNKPQGPPPPPGKPQGP----PPQGGNKPQGPPP---PGKPQGPPPQGDK-----S 87
Query: 422 RSKGRTPGSSYPRLPRGQGAYRP 444
RS PG P+ P QG +P
Sbjct: 88 RSPRSPPGK--PQGPPPQGGNQP 108
Score = 35.8 bits (81), Expect = 0.083
Identities = 31/109 (28%), Positives = 41/109 (37%), Gaps = 16/109 (14%)
Query: 338 DPPKPSRGPWRQPERRHPKGGECHAP--KGTRDTQELPPPEGPLKEPMDLKPEPHSQGVE 395
+P PS +P+ P G+ P +G Q PPP P P QG +
Sbjct: 35 NPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--------QGPPPQGDK 86
Query: 396 GPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQGAYRP 444
PG QGPPP+ + +G P P+ P QG RP
Sbjct: 87 SRSPRSPPGKPQGPPPQ------GGNQPQGPPPPPGKPQGPPPQGGNRP 129
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 44.3 bits (103), Expect = 2e-04
Identities = 55/186 (29%), Positives = 62/186 (33%), Gaps = 23/186 (12%)
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSN 325
Q PP P G PP + P + PPP PV PG
Sbjct: 234 QTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPP-PVL-------FPGQPFG 285
Query: 326 QQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPP-PEGPLKEPMD 384
Q LG PP P GP P P+ G P PP P GPL P+
Sbjct: 286 QPPLGPLPPGP-PPPVPGYGP--PPGPPPPQQGPPPPPG------PFPPRPPGPLGPPLT 336
Query: 385 LKPEPHSQGVEGPPQEKGPGSWQGPP--PRRTRDCVRWERSKGRTPGSSYPR-LPRGQGA 441
L P PH G PP P P P T + S+G P Y R P +G
Sbjct: 337 LAPPPHLPG--PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGD 394
Query: 442 YRPGTR 447
Y P R
Sbjct: 395 YGPPGR 400
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 44.3 bits (103), Expect = 2e-04
Identities = 50/185 (27%), Positives = 69/185 (37%), Gaps = 23/185 (12%)
Query: 264 SLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTR 323
SL +P A A SA S S+ + S+S + P P E P T
Sbjct: 456 SLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAP-----EPEPPT- 509
Query: 324 SNQQRLGETQKAMLDPPKPSRGPWR-QPERRHP--KGGECHAPKGTRDTQELPPPEGPLK 380
+N+ +L + P P GP +P RRHP KG A + PPP+ K
Sbjct: 510 TNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSK 569
Query: 381 EPMDLKPEPH--------SQGVEGPPQEKGPGSWQGPPPRR------TRDCVRWERSKGR 426
P PH S + PPQ + G+ Q P + +R ++ ER G
Sbjct: 570 APRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGL 629
Query: 427 TPGSS 431
P S
Sbjct: 630 LPYGS 634
Score = 30.8 bits (68), Expect = 2.7
Identities = 43/202 (21%), Positives = 75/202 (37%), Gaps = 25/202 (12%)
Query: 212 LKAAPEP------QQPMELYQPSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYFISL 265
L P+P Q+ E QP A E+R + + + E + + I L
Sbjct: 770 LSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRL 829
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSN 325
++ + +S+ S + T + S+ + + LPPP PV++ P + +
Sbjct: 830 EKE---IKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPP-PVSSSSQKPAKPALKRS 885
Query: 326 QQRLGETQKAMLDPPKPSRGPWRQ------PERRHPKGGECHAPKGTRDTQELPPPEGPL 379
++ E DPPK + P++R +G KG+R + E G
Sbjct: 886 RR---EADTCGQDPPKSASSTKSNHKDSSIPKQRRVEG------KGSRSSSEHKGSSGDT 936
Query: 380 KEPMDLKPEPHSQGVEGPPQEK 401
P + P+ G PQ K
Sbjct: 937 ANPFPVPSLPNGNSKPGKPQVK 958
>gi|18641360 collectin sub-family member 12 [Homo sapiens]
Length = 742
Score = 43.9 bits (102), Expect = 3e-04
Identities = 33/95 (34%), Positives = 43/95 (45%), Gaps = 12/95 (12%)
Query: 320 PGTRSNQQRLGETQKAMLDPPKPSR-----GPWRQPERRHPKGGE-CHAPKGTRDTQELP 373
PG N+ + GE K PP P+ GP P R KG + PKG+R + P
Sbjct: 460 PGPTGNKGQKGE--KGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKP 517
Query: 374 PPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQG 408
P+GP +P P G EG P +GP +QG
Sbjct: 518 GPQGPSGDP----GPPGPPGKEGLPGPQGPPGFQG 548
Score = 36.6 bits (83), Expect = 0.049
Identities = 46/160 (28%), Positives = 55/160 (34%), Gaps = 24/160 (15%)
Query: 262 FISLQQPPAPAEPESAVDVSKGSQ-PPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIP 320
F LQ PP P P +GSQ PP + + P P P
Sbjct: 438 FTILQGPPGPRGPRG----DRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPP 493
Query: 321 GTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGP-- 378
G R + G PK SRG +P + P G P G + LP P+GP
Sbjct: 494 GERGGKGSKGS------QGPKGSRGSPGKPGPQGPSGDP--GPPGPPGKEGLPGPQGPPG 545
Query: 379 -------LKEPMDLKPE--PHSQGVEGPPQEKGPGSWQGP 409
+ EP P P GV G P KGP GP
Sbjct: 546 FQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGP 585
Score = 32.0 bits (71), Expect = 1.2
Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 9/80 (11%)
Query: 363 PKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRR----TRDCV 418
P+G R +Q P P G + K E G GP E+GP GPP R ++
Sbjct: 450 PRGDRGSQGPPGPTGNKGQ----KGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQ 505
Query: 419 RWERSKGRTPGSSYPRLPRG 438
+ S+G +PG P+ P G
Sbjct: 506 GPKGSRG-SPGKPGPQGPSG 524
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 43.5 bits (101), Expect = 4e-04
Identities = 62/224 (27%), Positives = 76/224 (33%), Gaps = 24/224 (10%)
Query: 250 GIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPP--- 306
GI L+ ER PP P + S PP A + PP
Sbjct: 1204 GIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQ 1263
Query: 307 --PLPVATQHICEKIPGTRSNQQRL-GETQKAMLDPPKPSRGPWRQPERRHPKGGECHAP 363
P P + PG + L GE L P GP P + G C
Sbjct: 1264 GPPGPDGPRG-APGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPG--CDGK 1320
Query: 364 KGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGP-----PPRRTRDCV 418
G + P P+GP P P +G+ GPP KGP GP PP DC
Sbjct: 1321 DGQKGPVGFPGPQGPHGFP----GPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCP 1376
Query: 419 RWERSKGRTPGSSYPR----LPRGQGAYRPGTRRESLGLESKDG 458
R G PG P LP +G PG + E GL+ + G
Sbjct: 1377 RIPGLPG-APGMRGPEGAMGLPGMRGPSGPGCKGEP-GLDGRRG 1418
Score = 40.8 bits (94), Expect = 0.003
Identities = 40/131 (30%), Positives = 51/131 (38%), Gaps = 18/131 (13%)
Query: 339 PPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPL----------KEPMDLKPE 388
PP P P + ER P G +P G R + P P G + P D+ P+
Sbjct: 1199 PPGPVGIPGLKGERGDP-GSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDI-PD 1256
Query: 389 PHSQGVEGPPQEKGPGSWQGPPP-RRTRDCVRWERSKGRTPGSSYPRLPRGQGAYRPGTR 447
P G +GPP GP GPP + D +R E PG P P G Y+
Sbjct: 1257 PGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFP- 1315
Query: 448 RESLGLESKDG 458
G + KDG
Sbjct: 1316 ----GCDGKDG 1322
Score = 31.2 bits (69), Expect = 2.1
Identities = 30/109 (27%), Positives = 39/109 (35%), Gaps = 28/109 (25%)
Query: 360 CHAPKGTRDTQELPPPEGPLKE-----PMDLKPEPHSQGVEGPP------QEKGP----- 403
C KG+R P P+GP+ P+ L E +G GPP +KGP
Sbjct: 57 CVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPG 116
Query: 404 -------GSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQGAYRPG 445
GPP R + + G P P G+GA PG
Sbjct: 117 FPGLDGIPGHPGPPGPRGKPGM-----SGHNGSRGDPGFPGGRGALGPG 160
Score = 29.6 bits (65), Expect = 6.0
Identities = 38/142 (26%), Positives = 52/142 (36%), Gaps = 18/142 (12%)
Query: 305 PPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQP--------ERRHPK 356
PP LP +H PG N+ G+ + + K RGP P R
Sbjct: 537 PPGLP--GKHGASGPPG---NKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGH 591
Query: 357 GGECHAPKGTRDTQELPPP----EGPLKEPMDLKPE-PHSQGVEGPPQEKGPGSWQGPPP 411
GE P D ++ P GPL P P P G GPP E+G G P
Sbjct: 592 AGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPG 651
Query: 412 RRTRDCVRWERSKGRTPGSSYP 433
R D ++ ++ + +YP
Sbjct: 652 VRGPDGLKGQKGDTISCNVTYP 673
Score = 29.3 bits (64), Expect = 7.8
Identities = 31/99 (31%), Positives = 35/99 (35%), Gaps = 2/99 (2%)
Query: 363 PKGTRDTQELPPPEGPL-KEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWE 421
PKG + P P G L P+ LK P G G E G GPP R
Sbjct: 342 PKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACA 401
Query: 422 RSKGRTPGSSYPRLPRGQG-AYRPGTRRESLGLESKDGS 459
G +P LP G A PG + G K GS
Sbjct: 402 GMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGS 440
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 43.5 bits (101), Expect = 4e-04
Identities = 51/244 (20%), Positives = 93/244 (38%), Gaps = 21/244 (8%)
Query: 169 MEQELKAQGQEQEQERQHATTKQKAVGV-----QCPVCREPLVYDLASLKAAPEPQQPME 223
M+Q+ +A Q+Q+Q +Q +Q + + Q ++ + +A L+ + QQ +
Sbjct: 196 MQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQ 255
Query: 224 LYQPSAESLRQQE--ERKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVS 281
Q ++L+ Q ++ + Q Q + + ++ + Q PP P +P A +
Sbjct: 256 QQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP 315
Query: 282 KGSQPPST---LAAELSTSPAVQSTLPPPL-----PVATQHICEKIPGTRSNQQRLGETQ 333
P S L ++ P PPL P+ Q + P + Q + Q
Sbjct: 316 SQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ-PQVQQQQTAVQTAQ 374
Query: 334 KAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQG 393
A + P P P G+ + Q +PPP P +P +P+S
Sbjct: 375 AAQMVAPGVQVSQSSLPMLSSPSPGQ-----QVQTPQSMPPPPQPSPQPGQPSSQPNSNV 429
Query: 394 VEGP 397
GP
Sbjct: 430 SSGP 433
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 43.5 bits (101), Expect = 4e-04
Identities = 55/202 (27%), Positives = 84/202 (41%), Gaps = 38/202 (18%)
Query: 267 QPPAPAEP---ESAVDVSKGSQP-PSTLAAE--LSTSPAVQS--TLPPPLPVATQHICEK 318
QP PA+P ++ + QP P LA + +PA Q PP V T +
Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Query: 319 IPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGP 378
PG +S + G T+ + P GP + P ++ A G Q+ P + P
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQP-----GPGKIPAQQ--------AGPGKTSAQQTGPTKPP 470
Query: 379 LKEPMDLKPEPHSQG-VEGPPQEKG--------PGSWQGPPPRRTRDCVRWERSKGRTPG 429
+ P KP P G + PPQ+ G PGS + PPP++ + + PG
Sbjct: 471 SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK-PPPQQPGPA----KPSPQQPG 525
Query: 430 SSYPRLPRGQ-GAYRPGTRRES 450
S+ P P Q G+ +P ++ S
Sbjct: 526 STKP--PSQQPGSAKPSAQQPS 545
Score = 38.1 bits (87), Expect = 0.017
Identities = 57/252 (22%), Positives = 93/252 (36%), Gaps = 23/252 (9%)
Query: 209 LASLKAAPEPQQPMELYQPSAESLRQQEERKRLYQRQQERG-GIID--LEAERNRYFISL 265
L+++ + P +L S S + +++++ Q++Q + GII L+ + +
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQ 222
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAEL-STSPAVQSTLPPPLPVATQHICEKI----- 319
Q P + S SQ P + ++ T +Q P T H +
Sbjct: 223 QGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTP---QTDHAKLPLQRDAS 279
Query: 320 -PGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGP 378
P T+ GE+ K L P PS+ P +QP P + K + P
Sbjct: 280 RPQTKQADIVRGESVKPSL--PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG 337
Query: 379 LKEPMDLKPEPHSQGVEGPPQEKGPGSWQGP--PPRRTRDCVRWERSKGRTPGSSYPRLP 436
L +P+ +P V+ P K P GP PP + E+ PG P
Sbjct: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS---EKPSSEQPGPKALAQP 394
Query: 437 RGQG---AYRPG 445
G G A +PG
Sbjct: 395 PGVGKTPAQQPG 406
Score = 31.6 bits (70), Expect = 1.6
Identities = 56/280 (20%), Positives = 106/280 (37%), Gaps = 49/280 (17%)
Query: 180 QEQERQHATTKQKAVG-----VQCPVCREPLVYDLASLKAAPEPQQ---PMELYQPSAES 231
+E+ RQ A +A G V P ++ L ++ P+Q P + +P+
Sbjct: 50 EEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPG 109
Query: 232 LRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLA 291
L + Q+ G R+ ISL++ + + + + K S P L+
Sbjct: 110 LSKSRTTDTFRSEQKLPG--------RSPSTISLKESKSRTDLK---EEHKSSMMPGFLS 158
Query: 292 AELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPE 351
E++ AV S + P + I + ++Q+ + QK + G + P
Sbjct: 159 -EVNALSAVSSVVNKFNPF------DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL 211
Query: 352 RRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPP 411
++ P PK +P +GP ++P+ P S + P + K G P
Sbjct: 212 QQQP-------PK------PIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPI 258
Query: 412 RRTRDCVRWERSKGRTPGSSYPRLPRGQGAYRPGTRRESL 451
+ +TP + + +LP + A RP T++ +
Sbjct: 259 Q----------GPTQTPQTDHAKLPLQRDASRPQTKQADI 288
Score = 30.0 bits (66), Expect = 4.6
Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 368 DTQELPP-PEGPLKEPMDLKPEPHSQGVEGPPQEK 401
D +++PP P GP PM + E SQ PPQ K
Sbjct: 1121 DIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK 1155
Score = 29.3 bits (64), Expect = 7.8
Identities = 44/212 (20%), Positives = 79/212 (37%), Gaps = 24/212 (11%)
Query: 199 PVCREPLVYDLASLKAA--PEPQQPMELYQPSAESLRQQEERKRLYQRQQERGGIIDLEA 256
P+ ++P ++ S KA PE + P S+ ++++ + + ++ ++
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764
Query: 257 ERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTS-PAVQSTLPP------PLP 309
+ + +P P+ + K + P T +A+ S S P + P P P
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824
Query: 310 VATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDT 369
+ I PG S + G+ Q +DP + P + + PK PKG+
Sbjct: 825 ASDSKIISH-PGPSSESK--GQKQ---VDPVQKKEEPKKAQTKMSPKPDAKPMPKGS--- 875
Query: 370 QELPPPEGPLKEPMDLKPEPHSQGVEGPPQEK 401
P P GP P P PQE+
Sbjct: 876 ---PTPPGPRPTAGQTVPTPQQ---SPKPQEQ 901
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 43.5 bits (101), Expect = 4e-04
Identities = 55/202 (27%), Positives = 84/202 (41%), Gaps = 38/202 (18%)
Query: 267 QPPAPAEP---ESAVDVSKGSQP-PSTLAAE--LSTSPAVQS--TLPPPLPVATQHICEK 318
QP PA+P ++ + QP P LA + +PA Q PP V T +
Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Query: 319 IPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGP 378
PG +S + G T+ + P GP + P ++ A G Q+ P + P
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQP-----GPGKIPAQQ--------AGPGKTSAQQTGPTKPP 470
Query: 379 LKEPMDLKPEPHSQG-VEGPPQEKG--------PGSWQGPPPRRTRDCVRWERSKGRTPG 429
+ P KP P G + PPQ+ G PGS + PPP++ + + PG
Sbjct: 471 SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK-PPPQQPGPA----KPSPQQPG 525
Query: 430 SSYPRLPRGQ-GAYRPGTRRES 450
S+ P P Q G+ +P ++ S
Sbjct: 526 STKP--PSQQPGSAKPSAQQPS 545
Score = 38.1 bits (87), Expect = 0.017
Identities = 57/252 (22%), Positives = 93/252 (36%), Gaps = 23/252 (9%)
Query: 209 LASLKAAPEPQQPMELYQPSAESLRQQEERKRLYQRQQERG-GIID--LEAERNRYFISL 265
L+++ + P +L S S + +++++ Q++Q + GII L+ + +
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQ 222
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAEL-STSPAVQSTLPPPLPVATQHICEKI----- 319
Q P + S SQ P + ++ T +Q P T H +
Sbjct: 223 QGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTP---QTDHAKLPLQRDAS 279
Query: 320 -PGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGP 378
P T+ GE+ K L P PS+ P +QP P + K + P
Sbjct: 280 RPQTKQADIVRGESVKPSL--PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG 337
Query: 379 LKEPMDLKPEPHSQGVEGPPQEKGPGSWQGP--PPRRTRDCVRWERSKGRTPGSSYPRLP 436
L +P+ +P V+ P K P GP PP + E+ PG P
Sbjct: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS---EKPSSEQPGPKALAQP 394
Query: 437 RGQG---AYRPG 445
G G A +PG
Sbjct: 395 PGVGKTPAQQPG 406
Score = 31.6 bits (70), Expect = 1.6
Identities = 56/280 (20%), Positives = 106/280 (37%), Gaps = 49/280 (17%)
Query: 180 QEQERQHATTKQKAVG-----VQCPVCREPLVYDLASLKAAPEPQQ---PMELYQPSAES 231
+E+ RQ A +A G V P ++ L ++ P+Q P + +P+
Sbjct: 50 EEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPG 109
Query: 232 LRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLA 291
L + Q+ G R+ ISL++ + + + + K S P L+
Sbjct: 110 LSKSRTTDTFRSEQKLPG--------RSPSTISLKESKSRTDLK---EEHKSSMMPGFLS 158
Query: 292 AELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPE 351
E++ AV S + P + I + ++Q+ + QK + G + P
Sbjct: 159 -EVNALSAVSSVVNKFNPF------DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL 211
Query: 352 RRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPP 411
++ P PK +P +GP ++P+ P S + P + K G P
Sbjct: 212 QQQP-------PK------PIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPI 258
Query: 412 RRTRDCVRWERSKGRTPGSSYPRLPRGQGAYRPGTRRESL 451
+ +TP + + +LP + A RP T++ +
Sbjct: 259 Q----------GPTQTPQTDHAKLPLQRDASRPQTKQADI 288
Score = 30.0 bits (66), Expect = 4.6
Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 368 DTQELPP-PEGPLKEPMDLKPEPHSQGVEGPPQEK 401
D +++PP P GP PM + E SQ PPQ K
Sbjct: 1121 DIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK 1155
Score = 29.3 bits (64), Expect = 7.8
Identities = 44/212 (20%), Positives = 79/212 (37%), Gaps = 24/212 (11%)
Query: 199 PVCREPLVYDLASLKAA--PEPQQPMELYQPSAESLRQQEERKRLYQRQQERGGIIDLEA 256
P+ ++P ++ S KA PE + P S+ ++++ + + ++ ++
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764
Query: 257 ERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTS-PAVQSTLPP------PLP 309
+ + +P P+ + K + P T +A+ S S P + P P P
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824
Query: 310 VATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDT 369
+ I PG S + G+ Q +DP + P + + PK PKG+
Sbjct: 825 ASDSKIISH-PGPSSESK--GQKQ---VDPVQKKEEPKKAQTKMSPKPDAKPMPKGS--- 875
Query: 370 QELPPPEGPLKEPMDLKPEPHSQGVEGPPQEK 401
P P GP P P PQE+
Sbjct: 876 ---PTPPGPRPTAGQTVPTPQQ---SPKPQEQ 901
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 43.1 bits (100), Expect = 5e-04
Identities = 52/209 (24%), Positives = 69/209 (33%), Gaps = 48/209 (22%)
Query: 207 YDLASLKAAPEPQQPMELYQPSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQ 266
+DL +L PE + ++ S L+ +E K +Y ++ GG+ EA +N
Sbjct: 223 FDLNNLD--PELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGV---EAVKNELRRQAP 277
Query: 267 QPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQ 326
PP P S+G PP P ++ PPP P +
Sbjct: 278 PPPPP---------SRGGPPP--------PPPPPHNSGPPPPPARGRG------------ 308
Query: 327 QRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEG-PLKEPMDL 385
PP PSR P P P P + PPP P P
Sbjct: 309 ----------APPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGP 358
Query: 386 KPEPHS---QGVEGPPQEKGPGSWQGPPP 411
P P S G PP P GPPP
Sbjct: 359 PPPPPSVLGVGPVAPPPPPPPPPPPGPPP 387
Score = 30.8 bits (68), Expect = 2.7
Identities = 20/57 (35%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 356 KGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPR 412
K G A K Q PPP P P PH+ G PP +G G+ PP R
Sbjct: 261 KTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSG-PPPPPARGRGAPPPPPSR 316
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 43.1 bits (100), Expect = 5e-04
Identities = 47/176 (26%), Positives = 63/176 (35%), Gaps = 13/176 (7%)
Query: 268 PPAPAEPESAVDVSKGSQPPSTLAAELST---SPAVQSTLPPPLPVATQHICEKIPGTRS 324
PP+P +A + KG+ P+T AA L + PA S P P A K G +
Sbjct: 1040 PPSPKGSPAATPLPKGA--PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK--GGPA 1095
Query: 325 NQQRLGETQKAMLDPPKPSRGPWRQPERRHPK--GGECHAPKGTRDTQELPPPEGPLKEP 382
G PP P G P + P +PKG T PPP+G P
Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT---PPPKGAPTTP 1152
Query: 383 MDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRG 438
P P G+ PP + P + PP T ++ P P+G
Sbjct: 1153 AATPPSPKG-GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207
Score = 43.1 bits (100), Expect = 5e-04
Identities = 41/151 (27%), Positives = 53/151 (35%), Gaps = 14/151 (9%)
Query: 271 PAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPP--LPVATQHICEKIPGTRSNQQR 328
P P+ + P+T AA SP PPP P + G +
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAAT-PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283
Query: 329 LGETQKAMLDPPKPSRGPWRQPER--RHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLK 386
G A++ PP P GP P + P +PKG+ T PPP+G P
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT---PPPKGAPTPPAVTP 1340
Query: 387 PEPHSQGV--EGPPQEKG----PGSWQGPPP 411
P P P KG P S +GP P
Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
Score = 39.7 bits (91), Expect = 0.006
Identities = 44/150 (29%), Positives = 56/150 (37%), Gaps = 14/150 (9%)
Query: 268 PPAPAEPESAVDVSKG-SQPPSTLAAELSTSPAVQSTLP---PPLPVATQHICEKIPGTR 323
PP+P +A KG S PP+ SPA + LP P P AT + P T
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA-TPLPKGAPTTPAATLPSPKGGPATP 1074
Query: 324 SNQQRLGETQKAMLDPPKPSRGPWRQPER--RHPKGGECHAPKGTRDTQELPPPEGPLKE 381
S + G PP P GP + P +PKG T PP +G
Sbjct: 1075 SLK---GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT---PPHKGAPTT 1128
Query: 382 PMDLKPEPHSQGVEGPPQEKGPGSWQGPPP 411
P P P G+ PP + P + PP
Sbjct: 1129 PAATPPSPKG-GLATPPPKGAPTTPAATPP 1157
Score = 38.9 bits (89), Expect = 0.010
Identities = 38/168 (22%), Positives = 59/168 (35%), Gaps = 24/168 (14%)
Query: 268 PPAPAEPESAVDVSKGSQP---------------PSTLAAELSTSPAVQSTLPPPLPVAT 312
PP+P EP + V+ S P P+ + + PA S+ P+
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 313 QHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDT--Q 370
+ +K P T + ++ L + P K P + P E +P + +
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591
Query: 371 ELPPPEGPLKEPMDLKPEPHS----QGVEGPPQEKGPGSWQGPPPRRT 414
P P+ L P P P V P EKGP + P P+ T
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT---PAPKGT 1636
Score = 33.9 bits (76), Expect = 0.32
Identities = 56/270 (20%), Positives = 79/270 (29%), Gaps = 16/270 (5%)
Query: 170 EQELKAQGQEQEQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSA 229
E L QG + H+ T G P PL S K P P E PS
Sbjct: 838 ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL-----SPKGVTLP--PKETPTPSV 890
Query: 230 ESLRQQEERKRLYQRQQERG-GIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPS 288
+L +E +Q + ++ R + + PA P+ A + PPS
Sbjct: 891 VNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA-PTPPAATPPS 949
Query: 289 TLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWR 348
+ SP T P P + + G + G PP P GP
Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPK-------GGPATPSPKGAPTPPAATPPSPKGGPAT 1002
Query: 349 QPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQG 408
+ P P P P+G P P P P + P +
Sbjct: 1003 PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062
Query: 409 PPPRRTRDCVRWERSKGRTPGSSYPRLPRG 438
P TP ++ P P+G
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092
Score = 33.1 bits (74), Expect = 0.54
Identities = 36/148 (24%), Positives = 48/148 (32%), Gaps = 47/148 (31%)
Query: 269 PAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQR 328
P P E + + S PP+ + +P+ + L P P S +
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP-------------PAVTSPSPK 1611
Query: 329 LGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPE 388
T A + PP P +GP APKGT P P P LK
Sbjct: 1612 EAPTPPA-VTPPSPEKGP------------ATPAPKGT--------PTSPPVTPSSLKDS 1650
Query: 389 PHS-------------QGVEGPPQEKGP 403
P S Q +G P +KGP
Sbjct: 1651 PTSPASVTCKMGATVPQASKGLPAKKGP 1678
Score = 29.3 bits (64), Expect = 7.8
Identities = 30/130 (23%), Positives = 43/130 (33%), Gaps = 19/130 (14%)
Query: 268 PPAP-----AEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLP---PPLPVATQHICEKI 319
PP+P P + PPS + + P T P PP P T +
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 320 PGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPL 379
P ++ G T + + P P P P KGG P + +P P+G
Sbjct: 1354 PSSKG-----GPTTPSSKEGPTP---PAATPSH---KGGPAMTPPSPKRGPAIPSPKGDP 1402
Query: 380 KEPMDLKPEP 389
P + P
Sbjct: 1403 TSPAVIPLSP 1412
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 42.7 bits (99), Expect = 7e-04
Identities = 67/307 (21%), Positives = 114/307 (37%), Gaps = 30/307 (9%)
Query: 167 QHMEQELKAQGQEQEQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQ 226
Q +EQ+ Q + +E +RQ +QK + Q R + + + QQ E +
Sbjct: 371 QQLEQQ---QRENEEHKRQLLAERQKRIEEQKEQRRR--LEEQQRREKELRKQQEREQRR 425
Query: 227 PSAESLRQQEERKRLYQRQQERGGIIDLEAERNR----------YFISLQ---QPPAPAE 273
E +R++EER+R Q+ + ++ + + R Y +SLQ Q P E
Sbjct: 426 HYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVE 485
Query: 274 PESAVDVSKGSQPPS--TLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGE 331
+ +G P A E+ AV+S P A+Q + E+ S Q
Sbjct: 486 KKPLYHYKEGMSPSEKPAWAKEIPHLVAVKS--QGPALTASQSVHEQPTKGLSGFQEALN 543
Query: 332 TQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPP----EGPLKEPMDLKP 387
++ P+ + P + + + R +++PP + + K
Sbjct: 544 VTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKN 603
Query: 388 EPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVR---WERSKGRTPGSSYP-RLPRGQGAYR 443
P + GP P P RRT + S G + SS P P QG +
Sbjct: 604 SPGNGSALGPRLGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQPSSQGGSQ 663
Query: 444 PGTRRES 450
PG++ S
Sbjct: 664 PGSQAGS 670
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 42.7 bits (99), Expect = 7e-04
Identities = 67/307 (21%), Positives = 114/307 (37%), Gaps = 30/307 (9%)
Query: 167 QHMEQELKAQGQEQEQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQ 226
Q +EQ+ Q + +E +RQ +QK + Q R + + + QQ E +
Sbjct: 371 QQLEQQ---QRENEEHKRQLLAERQKRIEEQKEQRRR--LEEQQRREKELRKQQEREQRR 425
Query: 227 PSAESLRQQEERKRLYQRQQERGGIIDLEAERNR----------YFISLQ---QPPAPAE 273
E +R++EER+R Q+ + ++ + + R Y +SLQ Q P E
Sbjct: 426 HYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVE 485
Query: 274 PESAVDVSKGSQPPS--TLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGE 331
+ +G P A E+ AV+S P A+Q + E+ S Q
Sbjct: 486 KKPLYHYKEGMSPSEKPAWAKEIPHLVAVKS--QGPALTASQSVHEQPTKGLSGFQEALN 543
Query: 332 TQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPP----EGPLKEPMDLKP 387
++ P+ + P + + + R +++PP + + K
Sbjct: 544 VTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKN 603
Query: 388 EPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVR---WERSKGRTPGSSYP-RLPRGQGAYR 443
P + GP P P RRT + S G + SS P P QG +
Sbjct: 604 SPGNGSALGPRLGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQPSSQGGSQ 663
Query: 444 PGTRRES 450
PG++ S
Sbjct: 664 PGSQAGS 670
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 42.7 bits (99), Expect = 7e-04
Identities = 38/158 (24%), Positives = 58/158 (36%), Gaps = 25/158 (15%)
Query: 262 FISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPA-----------------VQSTL 304
F+ + PP P P + ++ S P T + T P V+ L
Sbjct: 476 FLEQRSPPPPPPPPTLLN---SSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPAL 532
Query: 305 PPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERR---HPKGGECH 361
PP PV H + PG+ + + + Q + P +P QP + HP H
Sbjct: 533 QPPGPVGILHFSQ--PGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPH 590
Query: 362 APKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQ 399
P+ + Q+ PP P +P P H + PPQ
Sbjct: 591 QPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQ 628
Score = 32.7 bits (73), Expect = 0.71
Identities = 40/143 (27%), Positives = 54/143 (37%), Gaps = 17/143 (11%)
Query: 266 QQPPAPA-EPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPP-LPVATQHICEKIPGTR 323
++P PA +P V + SQP S A P Q LP P P H T+
Sbjct: 525 ERPVRPALQPPGPVGILHFSQPGS--ATTRPFIPPRQPFLPGPGQPFLPTH-------TQ 575
Query: 324 SNQQRLGETQKAMLDPPKPS-RGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEP 382
N Q G + P +P + P +QP +H H P Q PPP+ P + P
Sbjct: 576 PNLQ--GPLHPPLPPPHQPQPQQPQQQPPPQHQPP---HQPPHQPPPQHQPPPQHPPQHP 630
Query: 383 MDLKPEPHSQGVEGPPQEKGPGS 405
+ H + PP P S
Sbjct: 631 PQHQHHHHHHHLSVPPPPLMPMS 653
Score = 30.8 bits (68), Expect = 2.7
Identities = 43/167 (25%), Positives = 54/167 (32%), Gaps = 41/167 (24%)
Query: 266 QQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSN 325
Q PP P P + QP L P LPV H G
Sbjct: 318 QAPPPPPPPPQQQPIRSLFQP---------------QPLQPLLPVQHPHHPSPPQGMHMP 362
Query: 326 QQRLGETQKAMLDPPKPSRGPWRQPERRH---------------PKGGECHAPKGTRDTQ 370
Q ET + M+ PP + +QP+ H P P+ Q
Sbjct: 363 PQL--ETPRMMMTPPPVTP---QQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQ 417
Query: 371 ELP-PPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRD 416
P PPE P P P P+S PP+ W+ PPP + RD
Sbjct: 418 RFPGPPEFPQHTP---GPVPNS--FSQPPRLPLQDQWRAPPPPQDRD 459
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 42.7 bits (99), Expect = 7e-04
Identities = 42/147 (28%), Positives = 59/147 (40%), Gaps = 21/147 (14%)
Query: 321 GTRSNQQRLG----ETQKAMLDPPKPSRGPWRQP---ERRHPKGGECH-----APKGTRD 368
G +++QQ G + PP+P GP RQ ++R P G+ H P G+
Sbjct: 445 GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPL 504
Query: 369 TQELPPPEGPLKEP-MDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKG-- 425
Q LP P ++P P QG + P GPG+ PP R +R G
Sbjct: 505 PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA---PPAARPPASPSPQRQAGPP 561
Query: 426 ---RTPGSSYPRLPRGQGAYRPGTRRE 449
R S P P+ GA G +R+
Sbjct: 562 QATRQTSVSGPAPPKASGAPPGGQQRQ 588
Score = 37.7 bits (86), Expect = 0.022
Identities = 40/146 (27%), Positives = 52/146 (35%), Gaps = 28/146 (19%)
Query: 268 PPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSN-- 325
PP + + V+ G P AA SP+ Q PP + P S
Sbjct: 524 PPTQGQGRQSRPVAGGPGAPP--AARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAP 581
Query: 326 ---QQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGP---- 378
QQR G QK PP P+ GP RQ + P P+ T + P P GP
Sbjct: 582 PGGQQRQGPPQK----PPGPA-GPTRQASQAGP------VPRTGPPTTQQPRPSGPGPAG 630
Query: 379 ------LKEPMDLKPEPHSQGVEGPP 398
++P P P + GPP
Sbjct: 631 RPKPQLAQKPSQDVPPPATAAAGGPP 656
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 42.7 bits (99), Expect = 7e-04
Identities = 42/147 (28%), Positives = 59/147 (40%), Gaps = 21/147 (14%)
Query: 321 GTRSNQQRLG----ETQKAMLDPPKPSRGPWRQP---ERRHPKGGECH-----APKGTRD 368
G +++QQ G + PP+P GP RQ ++R P G+ H P G+
Sbjct: 445 GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPL 504
Query: 369 TQELPPPEGPLKEP-MDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKG-- 425
Q LP P ++P P QG + P GPG+ PP R +R G
Sbjct: 505 PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA---PPAARPPASPSPQRQAGPP 561
Query: 426 ---RTPGSSYPRLPRGQGAYRPGTRRE 449
R S P P+ GA G +R+
Sbjct: 562 QATRQTSVSGPAPPKASGAPPGGQQRQ 588
Score = 37.7 bits (86), Expect = 0.022
Identities = 40/146 (27%), Positives = 52/146 (35%), Gaps = 28/146 (19%)
Query: 268 PPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSN-- 325
PP + + V+ G P AA SP+ Q PP + P S
Sbjct: 524 PPTQGQGRQSRPVAGGPGAPP--AARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAP 581
Query: 326 ---QQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGP---- 378
QQR G QK PP P+ GP RQ + P P+ T + P P GP
Sbjct: 582 PGGQQRQGPPQK----PPGPA-GPTRQASQAGP------VPRTGPPTTQQPRPSGPGPAG 630
Query: 379 ------LKEPMDLKPEPHSQGVEGPP 398
++P P P + GPP
Sbjct: 631 RPKPQLAQKPSQDVPPPATAAAGGPP 656
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 42.7 bits (99), Expect = 7e-04
Identities = 56/227 (24%), Positives = 83/227 (36%), Gaps = 38/227 (16%)
Query: 199 PVCREPLVYDLASLKAAPEPQQPMELY-QPSAESLRQQEERKRLYQRQQERGGIIDLEAE 257
P +P + + A+ KA P P + + QPS E E + +
Sbjct: 266 PAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAEN------------- 312
Query: 258 RNRYFISLQQPPAPAEPESAVDVSKGSQPPST-------LAAELSTSPAVQSTLPPPLPV 310
S++ P PAE V+ QPPS L AE+ A +S P
Sbjct: 313 ------SVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAE 366
Query: 311 ATQHICEKIPGTR-SNQQRLGETQKAMLD-PPKPSRGPWRQ-PERRHPKGGECHAPKGTR 367
EK P + R QKA ++ P P+ G + P + P E +
Sbjct: 367 ILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVE----ETLA 422
Query: 368 DTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRT 414
D Q L P E P +E +L+ + P E+ P +Q P P+ T
Sbjct: 423 DVQPLLPEEAPREEARELQLSTAME----TPAEEAPTEFQSPLPKET 465
Score = 38.1 bits (87), Expect = 0.017
Identities = 59/262 (22%), Positives = 93/262 (35%), Gaps = 30/262 (11%)
Query: 178 QEQEQERQHATT-----KQKAVGVQCPVCREPLVYDLAS---LKAAPEP---QQPMELYQ 226
+E+ +E Q +T ++ Q P+ +E + ++ L AA EP + P E
Sbjct: 434 REEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARS 493
Query: 227 PSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQP----PAPA-----EPESA 277
P +E +E + E + AE + +++ P PA A E SA
Sbjct: 494 PLSEETSAEEAHAEVQSPLAEETTAEEASAEI-QLLAAIEAPADETPAEAQSPLSEETSA 552
Query: 278 VDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAML 337
+ Q PS + +P PP T + + E A +
Sbjct: 553 EEAPAEVQSPSAKGVSIEEAPL--ELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEV 610
Query: 338 DPPKPSRGPWR-QPERRHPKGGECHAPKGTRDTQELPPPEGPLKE-PMDLKPEPHSQG-- 393
PP P QP E P E+ PP P +E P +++P P +
Sbjct: 611 QPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPP--PAEEAPAEVQPPPAEEAPA 668
Query: 394 -VEGPPQEKGPGSWQGPPPRRT 414
V+ PP E+ P Q P T
Sbjct: 669 EVQPPPAEEAPAEVQSLPAEET 690
Score = 31.2 bits (69), Expect = 2.1
Identities = 32/143 (22%), Positives = 46/143 (32%), Gaps = 9/143 (6%)
Query: 174 KAQGQEQEQERQHATTKQKAVGVQCPVCRE--------PLVYDLASLKAAPEPQQPMELY 225
+A +E E Q ++ VQ P E P A ++ P + P E+
Sbjct: 600 EASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ 659
Query: 226 QPSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQ 285
P AE + + + E + E ++ PPA P V K S
Sbjct: 660 PPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSP 719
Query: 286 PPS-TLAAELSTSPAVQSTLPPP 307
P L E A PPP
Sbjct: 720 PADLLLTEEFPIGEASAEVSPPP 742
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,628,101
Number of Sequences: 37866
Number of extensions: 1522412
Number of successful extensions: 10005
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 720
Number of HSP's that attempted gapping in prelim test: 7096
Number of HSP's gapped (non-prelim): 2949
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.