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Search of human proteins with 34303932
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34303932 transmembrane and coiled-coil domains 5A [Homo
sapiens]
(288 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34303932 transmembrane and coiled-coil domains 5A [Homo sapiens] 565 e-161
gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens] 57 1e-08
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 57 1e-08
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 57 1e-08
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 55 7e-08
gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens] 55 7e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 55 7e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 55 7e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 55 7e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 55 7e-08
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 55 7e-08
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 55 7e-08
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 55 9e-08
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 55 9e-08
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 53 4e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 52 5e-07
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 52 5e-07
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 52 5e-07
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 52 5e-07
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 52 6e-07
gi|21735548 centrosomal protein 2 [Homo sapiens] 52 8e-07
gi|156104908 myosin heavy chain 6 [Homo sapiens] 51 1e-06
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 51 1e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 2e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 2e-06
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 50 2e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 50 2e-06
gi|187761324 shootin1 isoform a [Homo sapiens] 50 2e-06
gi|50511340 shootin1 isoform b [Homo sapiens] 50 2e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 3e-06
>gi|34303932 transmembrane and coiled-coil domains 5A [Homo sapiens]
Length = 288
Score = 565 bits (1455), Expect = e-161
Identities = 288/288 (100%), Positives = 288/288 (100%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE
Sbjct: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSS 120
DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSS
Sbjct: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSS 120
Query: 121 PDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEE 180
PDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEE
Sbjct: 121 PDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEE 180
Query: 181 LEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKIFCCLFFITLFFIRLLS 240
LEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKIFCCLFFITLFFIRLLS
Sbjct: 181 LEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKIFCCLFFITLFFIRLLS 240
Query: 241 YMFFHVRFINPDLLVNVLPKVLGRSTLWKLRCFFFPSLTLETEDMLPH 288
YMFFHVRFINPDLLVNVLPKVLGRSTLWKLRCFFFPSLTLETEDMLPH
Sbjct: 241 YMFFHVRFINPDLLVNVLPKVLGRSTLWKLRCFFFPSLTLETEDMLPH 288
>gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]
Length = 676
Score = 57.4 bits (137), Expect = 1e-08
Identities = 57/220 (25%), Positives = 103/220 (46%), Gaps = 27/220 (12%)
Query: 16 LNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTM--- 72
L D +++ E K++E E K+Q L++ + +TR + D + + + TT
Sbjct: 179 LQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKAD 238
Query: 73 ERERALQELEEETARLE---RKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETK 129
E E + +LE R E R+ +TL ++ L SQ Q +PD A+E
Sbjct: 239 EIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQ-----IQKAPDVAIE--V 291
Query: 130 VKLQQLEASYACQEKELLKVMKE----YAFVTQLCEDQALYIKKYQE-------TLKKIE 178
+ LE A +E+E+ +++++ A +T+L E+ A I + ++ TLK++E
Sbjct: 292 LTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLE 351
Query: 179 EELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTAR 218
E+L+ EV K ++ + K +EG TQ A+
Sbjct: 352 EKLKGQADYEEVKKELN---ILKSMEFAPSEGAGTQDAAK 388
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 57.4 bits (137), Expect = 1e-08
Identities = 55/191 (28%), Positives = 86/191 (45%), Gaps = 24/191 (12%)
Query: 20 LERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQ 79
LE Q +D NQ+L ++ KIQ+LESE+ ++ E EN+T + L+
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESEL---------QDLEMENQTLQKNLEELK 804
Query: 80 ELEEETARLERKNKTLVHSITELQQ--KLTRKSQKITNCEQSSPDGALEETKVKLQQLEA 137
+ +LE++NK+L ++L++ K K K + D LEE VK+ L
Sbjct: 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL-- 862
Query: 138 SYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMN 197
EKE + KE + C K+ +E +K+ +++ L RE LVS
Sbjct: 863 -----EKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLRE--DLVS-- 913
Query: 198 PVEKEHTSQNN 208
EK T Q N
Sbjct: 914 --EKLKTQQMN 922
Score = 50.8 bits (120), Expect = 1e-06
Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 29/198 (14%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
+E RL ++ N LE + Q ++ NQ L ++E + +RL
Sbjct: 763 IENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRL------------ 810
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQ-- 118
E+ EKEN++ E+ +LE++ +LE++NK L L + KI N E+
Sbjct: 811 -EQLEKENKSL---EQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN 866
Query: 119 ---SSPDGALEETKVKLQQLEASYACQEKELLK-VMKEYAFVTQLCED---QALYIKKYQ 171
S G +E+ V+L++LE + KEL+K + + L ED + L ++
Sbjct: 867 KTLSKEIGIYKESCVRLKELEK----ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMN 922
Query: 172 ETLKKIEEELEALFLERE 189
L+K+ ELE + L +E
Sbjct: 923 NDLEKLTHELEKIGLNKE 940
Score = 44.3 bits (103), Expect = 1e-04
Identities = 53/222 (23%), Positives = 103/222 (46%), Gaps = 30/222 (13%)
Query: 19 DLERDTQRIDEANQKLLLKIQERE---DKIQRLESEIIQTRGLVEDEEWEKENR---TTM 72
+LE + +++ N+ L KI + +KI+ LE E + E E+ENR T+
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQE---------NSELERENRKLKKTL 679
Query: 73 ERER----ALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEET 128
+ + L+ LE+E ++L+ +N L ++ L+ + +Q E + E+
Sbjct: 680 DSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ--LQLENKELESEKEQL 737
Query: 129 KVKLQQLEASYACQEKELLKVMK-----EYAFVTQLCEDQALYIKKYQETLKKIEEELEA 183
K L+ L+AS+ ++ E L+V E + + E+ I++ + L+ +E E +
Sbjct: 738 KKGLELLKASF--KKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQT 795
Query: 184 LFLEREVSKLVS--MNPVEKEHTSQNNEGTPTQKTARLFSKK 223
L E K+ S + +EKE+ S E + +K + K+
Sbjct: 796 LQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Score = 38.9 bits (89), Expect = 0.005
Identities = 50/209 (23%), Positives = 92/209 (44%), Gaps = 26/209 (12%)
Query: 10 KRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESE-IIQTRGLV--EDEEWEK 66
+ I +L LE T + Q+L + E QR + E ++Q+ + ED +WE+
Sbjct: 973 EEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWER 1032
Query: 67 ENRTT----MERERALQELEEETARLERKNKTLVHSITELQ--------QKLTRKSQKIT 114
E++ T ++ + L E+E A L+ + + L + +L+ Q L + Q ++
Sbjct: 1033 ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVS 1092
Query: 115 NCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETL 174
EQ++ L+ KLQ ++ Q L+ + E++ + K +E L
Sbjct: 1093 LQEQNT---TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDL 1149
Query: 175 K-------KIEEELEALFLEREVSKLVSM 196
K K E+LE L ER+ S+ S+
Sbjct: 1150 KSLYDSLIKDHEKLELLH-ERQASEYESL 1177
Score = 37.7 bits (86), Expect = 0.012
Identities = 50/215 (23%), Positives = 99/215 (46%), Gaps = 37/215 (17%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
+E+ RL Q N++S D DE + ++E+ ++ +LESE+ + + +
Sbjct: 286 IELKRLQQENMNLLS---DARSARMYRDELDA-----LREKAVRVDKLESEVSRYKERLH 337
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKL--TR-KSQKITNCE 117
D E+ K ++EL+E+ N+ L+ + T L+ +L TR +S K+ E
Sbjct: 338 DIEFYKAR---------VEELKED-------NQVLLETKTMLEDQLEGTRARSDKLHELE 381
Query: 118 QSSPDGALEETKVKLQQLEASYACQEKELLKVMKE---YAFVTQLCEDQALYIKKYQETL 174
+ + + K KL +E K++ ++M+E + D++L++ E +
Sbjct: 382 KEN-----LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQI 436
Query: 175 KKIEEELEA--LFLEREVSKLVSMNPVEKEHTSQN 207
+ E EA L EV++L S ++ E +Q+
Sbjct: 437 SRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQS 471
Score = 37.7 bits (86), Expect = 0.012
Identities = 54/208 (25%), Positives = 93/208 (44%), Gaps = 29/208 (13%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
EI + QS +N +L+ DL ++ ++++ + L + ER+ KI E+E +
Sbjct: 513 EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLR-ENSERQIKILEQENEHL-------- 563
Query: 62 EEWEKENRTTME-RERALQELEEETARLERKNKTLVHSITELQQKLTR----KSQKITNC 116
N+T R+R+ E +E++NK L SI E KL++ K Q
Sbjct: 564 ------NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKEL 617
Query: 117 EQSSPDG-ALEETKVKLQQLEASYACQEKEL--LKVMKEYAFVTQL----CEDQALYIKK 169
E G EE + +L LE +K++ LK+ E + E + +KK
Sbjct: 618 EHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKK 677
Query: 170 YQETLKKIEEELEALFLEREVSKLVSMN 197
++ K + +LE+ LE+E S+L N
Sbjct: 678 TLDSFKNLTFQLES--LEKENSQLDEEN 703
Score = 29.3 bits (64), Expect = 4.2
Identities = 35/186 (18%), Positives = 82/186 (44%), Gaps = 19/186 (10%)
Query: 27 IDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEE-ET 85
+ A++ L ++ ++ ED+ +L ++ +G +ED E +E+E+ L E + ET
Sbjct: 1184 LKSAHKNLEVEHRDLEDRYNQL----LKQKGQLED----LEKMLKVEQEKMLLENKNHET 1235
Query: 86 ARLERK-----NKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYA 140
E K N L H+ ++L K ++ + + L +K++ +LEA ++
Sbjct: 1236 VAAEYKKLCGENDRLNHTYSQLL-----KETEVLQTDHKNLKSLLNNSKLEQTRLEAEFS 1290
Query: 141 CQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPVE 200
+++ ++ + CE + +E + + ++++ L L+ +M +
Sbjct: 1291 KLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKD 1350
Query: 201 KEHTSQ 206
H Q
Sbjct: 1351 LFHVEQ 1356
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 57.4 bits (137), Expect = 1e-08
Identities = 55/191 (28%), Positives = 86/191 (45%), Gaps = 24/191 (12%)
Query: 20 LERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQ 79
LE Q +D NQ+L ++ KIQ+LESE+ ++ E EN+T + L+
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESEL---------QDLEMENQTLQKNLEELK 804
Query: 80 ELEEETARLERKNKTLVHSITELQQ--KLTRKSQKITNCEQSSPDGALEETKVKLQQLEA 137
+ +LE++NK+L ++L++ K K K + D LEE VK+ L
Sbjct: 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL-- 862
Query: 138 SYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMN 197
EKE + KE + C K+ +E +K+ +++ L RE LVS
Sbjct: 863 -----EKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLRE--DLVS-- 913
Query: 198 PVEKEHTSQNN 208
EK T Q N
Sbjct: 914 --EKLKTQQMN 922
Score = 50.8 bits (120), Expect = 1e-06
Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 29/198 (14%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
+E RL ++ N LE + Q ++ NQ L ++E + +RL
Sbjct: 763 IENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRL------------ 810
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQ-- 118
E+ EKEN++ E+ +LE++ +LE++NK L L + KI N E+
Sbjct: 811 -EQLEKENKSL---EQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN 866
Query: 119 ---SSPDGALEETKVKLQQLEASYACQEKELLK-VMKEYAFVTQLCED---QALYIKKYQ 171
S G +E+ V+L++LE + KEL+K + + L ED + L ++
Sbjct: 867 KTLSKEIGIYKESCVRLKELEK----ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMN 922
Query: 172 ETLKKIEEELEALFLERE 189
L+K+ ELE + L +E
Sbjct: 923 NDLEKLTHELEKIGLNKE 940
Score = 44.3 bits (103), Expect = 1e-04
Identities = 53/222 (23%), Positives = 103/222 (46%), Gaps = 30/222 (13%)
Query: 19 DLERDTQRIDEANQKLLLKIQERE---DKIQRLESEIIQTRGLVEDEEWEKENR---TTM 72
+LE + +++ N+ L KI + +KI+ LE E + E E+ENR T+
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQE---------NSELERENRKLKKTL 679
Query: 73 ERER----ALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEET 128
+ + L+ LE+E ++L+ +N L ++ L+ + +Q E + E+
Sbjct: 680 DSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ--LQLENKELESEKEQL 737
Query: 129 KVKLQQLEASYACQEKELLKVMK-----EYAFVTQLCEDQALYIKKYQETLKKIEEELEA 183
K L+ L+AS+ ++ E L+V E + + E+ I++ + L+ +E E +
Sbjct: 738 KKGLELLKASF--KKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQT 795
Query: 184 LFLEREVSKLVS--MNPVEKEHTSQNNEGTPTQKTARLFSKK 223
L E K+ S + +EKE+ S E + +K + K+
Sbjct: 796 LQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Score = 37.7 bits (86), Expect = 0.012
Identities = 50/215 (23%), Positives = 99/215 (46%), Gaps = 37/215 (17%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
+E+ RL Q N++S D DE + ++E+ ++ +LESE+ + + +
Sbjct: 286 IELKRLQQENMNLLS---DARSARMYRDELDA-----LREKAVRVDKLESEVSRYKERLH 337
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKL--TR-KSQKITNCE 117
D E+ K ++EL+E+ N+ L+ + T L+ +L TR +S K+ E
Sbjct: 338 DIEFYKAR---------VEELKED-------NQVLLETKTMLEDQLEGTRARSDKLHELE 381
Query: 118 QSSPDGALEETKVKLQQLEASYACQEKELLKVMKE---YAFVTQLCEDQALYIKKYQETL 174
+ + + K KL +E K++ ++M+E + D++L++ E +
Sbjct: 382 KEN-----LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQI 436
Query: 175 KKIEEELEA--LFLEREVSKLVSMNPVEKEHTSQN 207
+ E EA L EV++L S ++ E +Q+
Sbjct: 437 SRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQS 471
Score = 37.7 bits (86), Expect = 0.012
Identities = 54/208 (25%), Positives = 93/208 (44%), Gaps = 29/208 (13%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
EI + QS +N +L+ DL ++ ++++ + L + ER+ KI E+E +
Sbjct: 513 EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLR-ENSERQIKILEQENEHL-------- 563
Query: 62 EEWEKENRTTME-RERALQELEEETARLERKNKTLVHSITELQQKLTR----KSQKITNC 116
N+T R+R+ E +E++NK L SI E KL++ K Q
Sbjct: 564 ------NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKEL 617
Query: 117 EQSSPDG-ALEETKVKLQQLEASYACQEKEL--LKVMKEYAFVTQL----CEDQALYIKK 169
E G EE + +L LE +K++ LK+ E + E + +KK
Sbjct: 618 EHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKK 677
Query: 170 YQETLKKIEEELEALFLEREVSKLVSMN 197
++ K + +LE+ LE+E S+L N
Sbjct: 678 TLDSFKNLTFQLES--LEKENSQLDEEN 703
Score = 35.4 bits (80), Expect = 0.058
Identities = 52/231 (22%), Positives = 96/231 (41%), Gaps = 48/231 (20%)
Query: 6 LAQSKRNIISLNMDLERDTQRIDEAN---QKLLLKIQEREDKIQRLESEIIQTRGLVEDE 62
L K +N DLE+ T +++ ++LL Q +D+ + LES++ T
Sbjct: 911 LVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTL------ 964
Query: 63 EWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKL---------TRKSQKI 113
+++L+ EE+ A LE + + + +L+Q+L ++ Q
Sbjct: 965 ------------KKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
Query: 114 TNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFV-----TQLCEDQALYIK 168
QSSP + E+ K + + E + +ELLKV V T E QAL +
Sbjct: 1013 ERMVQSSPPISGEDNKWERESQETT-----RELLKVKDRLIEVERNNATLQAEKQALKTQ 1067
Query: 169 KYQETLKKIEEELEALFLEREVSKLVSMN--------PVEKEHTSQNNEGT 211
Q + + + L L+R+ L N ++ E+++ N++ T
Sbjct: 1068 LKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQST 1118
Score = 29.3 bits (64), Expect = 4.2
Identities = 35/186 (18%), Positives = 82/186 (44%), Gaps = 19/186 (10%)
Query: 27 IDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEE-ET 85
+ A++ L ++ ++ ED+ +L ++ +G +ED E +E+E+ L E + ET
Sbjct: 1183 LKSAHKNLEVEHRDLEDRYNQL----LKQKGQLED----LEKMLKVEQEKMLLENKNHET 1234
Query: 86 ARLERK-----NKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYA 140
E K N L H+ ++L K ++ + + L +K++ +LEA ++
Sbjct: 1235 VAAEYKKLCGENDRLNHTYSQLL-----KETEVLQTDHKNLKSLLNNSKLEQTRLEAEFS 1289
Query: 141 CQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPVE 200
+++ ++ + CE + +E + + ++++ L L+ +M +
Sbjct: 1290 KLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKD 1349
Query: 201 KEHTSQ 206
H Q
Sbjct: 1350 LFHVEQ 1355
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 55.1 bits (131), Expect = 7e-08
Identities = 55/220 (25%), Positives = 100/220 (45%), Gaps = 25/220 (11%)
Query: 16 LNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTM--- 72
L D +++ E K++E E K+Q L++ + +TR + D + + + TT
Sbjct: 168 LQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKAD 227
Query: 73 ERERALQELEEETARLE---RKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETK 129
E E + +LE R E R+ +TL ++ L SQ Q +PD
Sbjct: 228 EIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQ-----IQKAPDVEQAIEV 282
Query: 130 VKLQQLEASYACQEKELLKVMKE----YAFVTQLCEDQALYIKKYQE-------TLKKIE 178
+ LE A +E+E+ +++++ A +T+L E+ A I + ++ TLK++E
Sbjct: 283 LTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLE 342
Query: 179 EELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTAR 218
E+L+ EV K ++ + K +EG TQ A+
Sbjct: 343 EKLKGQADYEEVKKELN---ILKSMEFAPSEGAGTQDAAK 379
Score = 34.3 bits (77), Expect = 0.13
Identities = 50/211 (23%), Positives = 88/211 (41%), Gaps = 27/211 (12%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEA-NQKLLLKIQEREDKIQRLESEIIQTRGLV 59
+++ RL + L LE + E NQ++ +K + +KI+ E + +
Sbjct: 103 LKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALK--EKIREYEQTLKNQAETI 160
Query: 60 EDEEWEKENRTTMERERALQELE-EETARLERKNKTLVHSITELQQKLTRKSQKITNCEQ 118
E+ +K E+ER LQE + T++LE H + LQ L + ++ + +
Sbjct: 161 ALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAE----HKVQSLQTALEKTRTELFDLKT 216
Query: 119 SSPDGALEETKVKLQQLE------------ASYACQEKELLKVMKEYA-FVTQLCE--DQ 163
EET K ++E A A +E E L+ A QL +
Sbjct: 217 KYD----EETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQK 272
Query: 164 ALYIKKYQETLKKIEEELEALFLEREVSKLV 194
A +++ E L + E+E ERE+++LV
Sbjct: 273 APDVEQAIEVLTRSSLEVELAAKEREIAQLV 303
>gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens]
Length = 678
Score = 55.1 bits (131), Expect = 7e-08
Identities = 55/220 (25%), Positives = 100/220 (45%), Gaps = 25/220 (11%)
Query: 16 LNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTM--- 72
L D +++ E K++E E K+Q L++ + +TR + D + + + TT
Sbjct: 179 LQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKAD 238
Query: 73 ERERALQELEEETARLE---RKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETK 129
E E + +LE R E R+ +TL ++ L SQ Q +PD
Sbjct: 239 EIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQ-----IQKAPDVEQAIEV 293
Query: 130 VKLQQLEASYACQEKELLKVMKE----YAFVTQLCEDQALYIKKYQE-------TLKKIE 178
+ LE A +E+E+ +++++ A +T+L E+ A I + ++ TLK++E
Sbjct: 294 LTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLE 353
Query: 179 EELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTAR 218
E+L+ EV K ++ + K +EG TQ A+
Sbjct: 354 EKLKGQADYEEVKKELN---ILKSMEFAPSEGAGTQDAAK 390
Score = 34.3 bits (77), Expect = 0.13
Identities = 50/211 (23%), Positives = 88/211 (41%), Gaps = 27/211 (12%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEA-NQKLLLKIQEREDKIQRLESEIIQTRGLV 59
+++ RL + L LE + E NQ++ +K + +KI+ E + +
Sbjct: 114 LKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALK--EKIREYEQTLKNQAETI 171
Query: 60 EDEEWEKENRTTMERERALQELE-EETARLERKNKTLVHSITELQQKLTRKSQKITNCEQ 118
E+ +K E+ER LQE + T++LE H + LQ L + ++ + +
Sbjct: 172 ALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAE----HKVQSLQTALEKTRTELFDLKT 227
Query: 119 SSPDGALEETKVKLQQLE------------ASYACQEKELLKVMKEYA-FVTQLCE--DQ 163
EET K ++E A A +E E L+ A QL +
Sbjct: 228 KYD----EETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQK 283
Query: 164 ALYIKKYQETLKKIEEELEALFLEREVSKLV 194
A +++ E L + E+E ERE+++LV
Sbjct: 284 APDVEQAIEVLTRSSLEVELAAKEREIAQLV 314
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 55.1 bits (131), Expect = 7e-08
Identities = 47/212 (22%), Positives = 98/212 (46%), Gaps = 11/212 (5%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
E+ L Q+K+ + LE Q + E DK+ +L++E+ G++ +
Sbjct: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298
Query: 62 EEWE-----KENRTTMERERALQELEEETARLERKNKTLVHSITE----LQQKLTRKSQK 112
E + K+ + + + QEL +E R + T + + E LQ +L + +
Sbjct: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1358
Query: 113 ITNCEQ--SSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKY 170
N E+ S+ + L ++K KLQ ++ E+ + KE +TQ E++A K
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 171 QETLKKIEEELEALFLEREVSKLVSMNPVEKE 202
++T ++++EL+ L ++ + + + N +K+
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1450
Score = 47.4 bits (111), Expect = 1e-05
Identities = 49/226 (21%), Positives = 94/226 (41%), Gaps = 33/226 (14%)
Query: 5 RLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEW 64
+L ++ + +DLE + + A QKL L+ E KI++LE EI+
Sbjct: 940 QLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEIL----------- 988
Query: 65 EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCE--QSSPD 122
++++ +L ++ K L I++L L + +K N ++ +
Sbjct: 989 ---------------VMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 123 GALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELE 182
+ E +V+L++ E S EK K+ + + + D I + + L K EEEL+
Sbjct: 1034 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1093
Query: 183 ALFLEREVSKLVSMNPVEK-----EHTSQNNEGTPTQKTARLFSKK 223
A + N ++K H S E +++ AR ++K
Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1139
Score = 41.6 bits (96), Expect = 8e-04
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 21 ERDTQRIDEANQKLLL----KIQEREDKI----QRLESEIIQTRGLVEDEEWEKENRTTM 72
E D +D NQ+ L+ K Q + D++ + + S+ R E E EKE + +
Sbjct: 1428 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA-L 1486
Query: 73 ERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS--SPDGALEETKV 130
RAL+E E LER NK L + +L + + E+S + + +EE K
Sbjct: 1487 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1546
Query: 131 KLQQLEASYACQEKELLKV-MKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLERE 189
+L++LE E L++ + A Q D ++ +E ++++ +L E E
Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELE 1606
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/191 (21%), Positives = 85/191 (44%), Gaps = 12/191 (6%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRL--ESEIIQTRGLVEDEEWEKENRTTMERERAL 78
E + Q+ E QK +++E E K +L E ++Q + E E + + +
Sbjct: 858 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917
Query: 79 QELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEAS 138
QELEE +E + + +LQ + + +Q++ + E+ LEE + Q+L+
Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ-----LEEEEAARQKLQLE 972
Query: 139 YACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNP 198
E ++ K+ E + +DQ + K ++ L++ +L E E K ++
Sbjct: 973 KVTAEAKIKKLEDEIL----VMDDQNNKLSKERKLLEERISDLTTNLAEEE-EKAKNLTK 1027
Query: 199 VEKEHTSQNNE 209
++ +H S +E
Sbjct: 1028 LKNKHESMISE 1038
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/225 (18%), Positives = 93/225 (41%), Gaps = 9/225 (4%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQ-------RLESEIIQ 54
E+ L SK ++ +LE+ + ++ +++ +++E ED++Q RLE +
Sbjct: 1512 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 55 TRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKIT 114
+G E + ++ + +R + ++L E LE + K ++ +K K
Sbjct: 1572 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ--RALAAAAKKKLEGDLKDL 1629
Query: 115 NCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETL 174
+ S EE +L++L+A ++EL + ++ K + L
Sbjct: 1630 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1689
Query: 175 KKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARL 219
+++E+L A R+ + L E+ +S + + RL
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL 1734
Score = 36.2 bits (82), Expect = 0.034
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 34/178 (19%)
Query: 60 EDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQ- 118
E+E KE+ +ER Q+ E E LE+K+ L LQ++L +++ E+
Sbjct: 851 EEEMQAKEDELQKTKERQ-QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
Query: 119 ---------------SSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQ 163
+ LEE + + QQL+A +++L + E + Q
Sbjct: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL--EEQLEEEEAARQ 967
Query: 164 ALYIKKY--QETLKKIEEEL------------EALFLEREVSKLVSMNPVEKEHTSQN 207
L ++K + +KK+E+E+ E LE +S L + N E+E ++N
Sbjct: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT-NLAEEEEKAKN 1024
Score = 36.2 bits (82), Expect = 0.034
Identities = 32/139 (23%), Positives = 67/139 (48%), Gaps = 5/139 (3%)
Query: 42 EDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITE 101
+D+ +RLE+ I Q +E+E+ E + R +A Q+ E+ + L + T
Sbjct: 1728 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR-KATQQAEQLSNELATERST-AQKNES 1785
Query: 102 LQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCE 161
+Q+L R+++++ + + K + LEA A E+++ + +E T+ +
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Query: 162 DQALYIKKYQETLKKIEEE 180
+ KK +E L ++E+E
Sbjct: 1846 QKD---KKLKEILLQVEDE 1861
Score = 35.4 bits (80), Expect = 0.058
Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 4 SRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED-- 61
S +A + I L +E++ + A + L ++++ K++ + ++ R + E
Sbjct: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSL----KQKDKKLKEILLQVEDERKMAEQYK 1869
Query: 62 EEWEKENRTTMERERALQELEEETARLERKNKTLVHSITE 101
E+ EK N + +R L+E EEE+ R+ + L + E
Sbjct: 1870 EQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1909
Score = 33.9 bits (76), Expect = 0.17
Identities = 36/191 (18%), Positives = 82/191 (42%), Gaps = 10/191 (5%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
+ + + +S++ + L LE D E L +I E + ++ + E E+ ++
Sbjct: 1041 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1100
Query: 61 DEEWEKEN--RTTMERERALQELEEE-------TARLERKNKTLVHSITELQQKLTRKSQ 111
DE +K N + E E + +L+E+ + E++ + L + L+ +L +
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL-EDTL 1159
Query: 112 KITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQ 171
T +Q +E V + L+ E ++ ++ +++A + +Q K+ +
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219
Query: 172 ETLKKIEEELE 182
L K ++ LE
Sbjct: 1220 ANLDKNKQTLE 1230
Score = 33.5 bits (75), Expect = 0.22
Identities = 48/196 (24%), Positives = 83/196 (42%), Gaps = 38/196 (19%)
Query: 27 IDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETA 86
+DE + ++QE K + E+ E+ E+ R ++ Q LE+E A
Sbjct: 1183 LDEETRSHEAQVQEMRQKHAQAVEELT--------EQLEQFKRAKANLDKNKQTLEKENA 1234
Query: 87 RL--------------ERKNKTLVHSITELQQK----------LTRKSQKITNCEQSSPD 122
L E K K L + ELQ K L K K+ N E S
Sbjct: 1235 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN-EVESVT 1293
Query: 123 GALEETK---VKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLK-KIE 178
G L E + +KL + AS + Q ++ ++++E + +++ + +L+ +++
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 179 EELEA-LFLEREVSKL 193
EE+EA LER +S L
Sbjct: 1354 EEMEAKQNLERHISTL 1369
Score = 32.3 bits (72), Expect = 0.50
Identities = 31/162 (19%), Positives = 75/162 (46%), Gaps = 14/162 (8%)
Query: 74 RERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQ 133
+E +Q E+E + + + + + + EL+QK ++ +++ ++ A E + +
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ--AETELYAEAE 907
Query: 134 QLEASYACQEKELLKVMKEYAFVTQLCEDQALYI----KKYQETLKKIEEELE------- 182
++ A +++EL +++ E + ED+ + KK + + +EE+LE
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
Query: 183 ALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKI 224
L LE+ V+ + +E E +++ K +L ++I
Sbjct: 968 KLQLEK-VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1008
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 55.1 bits (131), Expect = 7e-08
Identities = 47/212 (22%), Positives = 98/212 (46%), Gaps = 11/212 (5%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
E+ L Q+K+ + LE Q + E DK+ +L++E+ G++ +
Sbjct: 1246 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1305
Query: 62 EEWE-----KENRTTMERERALQELEEETARLERKNKTLVHSITE----LQQKLTRKSQK 112
E + K+ + + + QEL +E R + T + + E LQ +L + +
Sbjct: 1306 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1365
Query: 113 ITNCEQ--SSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKY 170
N E+ S+ + L ++K KLQ ++ E+ + KE +TQ E++A K
Sbjct: 1366 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 171 QETLKKIEEELEALFLEREVSKLVSMNPVEKE 202
++T ++++EL+ L ++ + + + N +K+
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1457
Score = 47.4 bits (111), Expect = 1e-05
Identities = 49/226 (21%), Positives = 94/226 (41%), Gaps = 33/226 (14%)
Query: 5 RLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEW 64
+L ++ + +DLE + + A QKL L+ E KI++LE EI+
Sbjct: 947 QLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEIL----------- 995
Query: 65 EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCE--QSSPD 122
++++ +L ++ K L I++L L + +K N ++ +
Sbjct: 996 ---------------VMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1040
Query: 123 GALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELE 182
+ E +V+L++ E S EK K+ + + + D I + + L K EEEL+
Sbjct: 1041 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1100
Query: 183 ALFLEREVSKLVSMNPVEK-----EHTSQNNEGTPTQKTARLFSKK 223
A + N ++K H S E +++ AR ++K
Sbjct: 1101 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1146
Score = 41.6 bits (96), Expect = 8e-04
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 21 ERDTQRIDEANQKLLL----KIQEREDKI----QRLESEIIQTRGLVEDEEWEKENRTTM 72
E D +D NQ+ L+ K Q + D++ + + S+ R E E EKE + +
Sbjct: 1435 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA-L 1493
Query: 73 ERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS--SPDGALEETKV 130
RAL+E E LER NK L + +L + + E+S + + +EE K
Sbjct: 1494 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1553
Query: 131 KLQQLEASYACQEKELLKV-MKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLERE 189
+L++LE E L++ + A Q D ++ +E ++++ +L E E
Sbjct: 1554 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELE 1613
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/191 (21%), Positives = 85/191 (44%), Gaps = 12/191 (6%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRL--ESEIIQTRGLVEDEEWEKENRTTMERERAL 78
E + Q+ E QK +++E E K +L E ++Q + E E + + +
Sbjct: 865 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924
Query: 79 QELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEAS 138
QELEE +E + + +LQ + + +Q++ + E+ LEE + Q+L+
Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ-----LEEEEAARQKLQLE 979
Query: 139 YACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNP 198
E ++ K+ E + +DQ + K ++ L++ +L E E K ++
Sbjct: 980 KVTAEAKIKKLEDEIL----VMDDQNNKLSKERKLLEERISDLTTNLAEEE-EKAKNLTK 1034
Query: 199 VEKEHTSQNNE 209
++ +H S +E
Sbjct: 1035 LKNKHESMISE 1045
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/225 (18%), Positives = 93/225 (41%), Gaps = 9/225 (4%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQ-------RLESEIIQ 54
E+ L SK ++ +LE+ + ++ +++ +++E ED++Q RLE +
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1578
Query: 55 TRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKIT 114
+G E + ++ + +R + ++L E LE + K ++ +K K
Sbjct: 1579 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ--RALAAAAKKKLEGDLKDL 1636
Query: 115 NCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETL 174
+ S EE +L++L+A ++EL + ++ K + L
Sbjct: 1637 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1696
Query: 175 KKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARL 219
+++E+L A R+ + L E+ +S + + RL
Sbjct: 1697 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL 1741
Score = 36.2 bits (82), Expect = 0.034
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 34/178 (19%)
Query: 60 EDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQ- 118
E+E KE+ +ER Q+ E E LE+K+ L LQ++L +++ E+
Sbjct: 858 EEEMQAKEDELQKTKERQ-QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916
Query: 119 ---------------SSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQ 163
+ LEE + + QQL+A +++L + E + Q
Sbjct: 917 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL--EEQLEEEEAARQ 974
Query: 164 ALYIKKY--QETLKKIEEEL------------EALFLEREVSKLVSMNPVEKEHTSQN 207
L ++K + +KK+E+E+ E LE +S L + N E+E ++N
Sbjct: 975 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT-NLAEEEEKAKN 1031
Score = 36.2 bits (82), Expect = 0.034
Identities = 32/139 (23%), Positives = 67/139 (48%), Gaps = 5/139 (3%)
Query: 42 EDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITE 101
+D+ +RLE+ I Q +E+E+ E + R +A Q+ E+ + L + T
Sbjct: 1735 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR-KATQQAEQLSNELATERST-AQKNES 1792
Query: 102 LQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCE 161
+Q+L R+++++ + + K + LEA A E+++ + +E T+ +
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Query: 162 DQALYIKKYQETLKKIEEE 180
+ KK +E L ++E+E
Sbjct: 1853 QKD---KKLKEILLQVEDE 1868
Score = 35.4 bits (80), Expect = 0.058
Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 4 SRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED-- 61
S +A + I L +E++ + A + L ++++ K++ + ++ R + E
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSL----KQKDKKLKEILLQVEDERKMAEQYK 1876
Query: 62 EEWEKENRTTMERERALQELEEETARLERKNKTLVHSITE 101
E+ EK N + +R L+E EEE+ R+ + L + E
Sbjct: 1877 EQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1916
Score = 33.9 bits (76), Expect = 0.17
Identities = 36/191 (18%), Positives = 82/191 (42%), Gaps = 10/191 (5%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
+ + + +S++ + L LE D E L +I E + ++ + E E+ ++
Sbjct: 1048 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1107
Query: 61 DEEWEKEN--RTTMERERALQELEEE-------TARLERKNKTLVHSITELQQKLTRKSQ 111
DE +K N + E E + +L+E+ + E++ + L + L+ +L +
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL-EDTL 1166
Query: 112 KITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQ 171
T +Q +E V + L+ E ++ ++ +++A + +Q K+ +
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 172 ETLKKIEEELE 182
L K ++ LE
Sbjct: 1227 ANLDKNKQTLE 1237
Score = 33.5 bits (75), Expect = 0.22
Identities = 48/196 (24%), Positives = 83/196 (42%), Gaps = 38/196 (19%)
Query: 27 IDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETA 86
+DE + ++QE K + E+ E+ E+ R ++ Q LE+E A
Sbjct: 1190 LDEETRSHEAQVQEMRQKHAQAVEELT--------EQLEQFKRAKANLDKNKQTLEKENA 1241
Query: 87 RL--------------ERKNKTLVHSITELQQK----------LTRKSQKITNCEQSSPD 122
L E K K L + ELQ K L K K+ N E S
Sbjct: 1242 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN-EVESVT 1300
Query: 123 GALEETK---VKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLK-KIE 178
G L E + +KL + AS + Q ++ ++++E + +++ + +L+ +++
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 179 EELEA-LFLEREVSKL 193
EE+EA LER +S L
Sbjct: 1361 EEMEAKQNLERHISTL 1376
Score = 32.3 bits (72), Expect = 0.50
Identities = 31/162 (19%), Positives = 75/162 (46%), Gaps = 14/162 (8%)
Query: 74 RERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQ 133
+E +Q E+E + + + + + + EL+QK ++ +++ ++ A E + +
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ--AETELYAEAE 914
Query: 134 QLEASYACQEKELLKVMKEYAFVTQLCEDQALYI----KKYQETLKKIEEELE------- 182
++ A +++EL +++ E + ED+ + KK + + +EE+LE
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974
Query: 183 ALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKI 224
L LE+ V+ + +E E +++ K +L ++I
Sbjct: 975 KLQLEK-VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1015
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 55.1 bits (131), Expect = 7e-08
Identities = 47/212 (22%), Positives = 98/212 (46%), Gaps = 11/212 (5%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
E+ L Q+K+ + LE Q + E DK+ +L++E+ G++ +
Sbjct: 1246 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1305
Query: 62 EEWE-----KENRTTMERERALQELEEETARLERKNKTLVHSITE----LQQKLTRKSQK 112
E + K+ + + + QEL +E R + T + + E LQ +L + +
Sbjct: 1306 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1365
Query: 113 ITNCEQ--SSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKY 170
N E+ S+ + L ++K KLQ ++ E+ + KE +TQ E++A K
Sbjct: 1366 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 171 QETLKKIEEELEALFLEREVSKLVSMNPVEKE 202
++T ++++EL+ L ++ + + + N +K+
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1457
Score = 47.4 bits (111), Expect = 1e-05
Identities = 49/226 (21%), Positives = 94/226 (41%), Gaps = 33/226 (14%)
Query: 5 RLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEW 64
+L ++ + +DLE + + A QKL L+ E KI++LE EI+
Sbjct: 947 QLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEIL----------- 995
Query: 65 EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCE--QSSPD 122
++++ +L ++ K L I++L L + +K N ++ +
Sbjct: 996 ---------------VMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1040
Query: 123 GALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELE 182
+ E +V+L++ E S EK K+ + + + D I + + L K EEEL+
Sbjct: 1041 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1100
Query: 183 ALFLEREVSKLVSMNPVEK-----EHTSQNNEGTPTQKTARLFSKK 223
A + N ++K H S E +++ AR ++K
Sbjct: 1101 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1146
Score = 41.6 bits (96), Expect = 8e-04
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 21 ERDTQRIDEANQKLLL----KIQEREDKI----QRLESEIIQTRGLVEDEEWEKENRTTM 72
E D +D NQ+ L+ K Q + D++ + + S+ R E E EKE + +
Sbjct: 1435 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA-L 1493
Query: 73 ERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS--SPDGALEETKV 130
RAL+E E LER NK L + +L + + E+S + + +EE K
Sbjct: 1494 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1553
Query: 131 KLQQLEASYACQEKELLKV-MKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLERE 189
+L++LE E L++ + A Q D ++ +E ++++ +L E E
Sbjct: 1554 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELE 1613
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/191 (21%), Positives = 85/191 (44%), Gaps = 12/191 (6%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRL--ESEIIQTRGLVEDEEWEKENRTTMERERAL 78
E + Q+ E QK +++E E K +L E ++Q + E E + + +
Sbjct: 865 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924
Query: 79 QELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEAS 138
QELEE +E + + +LQ + + +Q++ + E+ LEE + Q+L+
Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ-----LEEEEAARQKLQLE 979
Query: 139 YACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNP 198
E ++ K+ E + +DQ + K ++ L++ +L E E K ++
Sbjct: 980 KVTAEAKIKKLEDEIL----VMDDQNNKLSKERKLLEERISDLTTNLAEEE-EKAKNLTK 1034
Query: 199 VEKEHTSQNNE 209
++ +H S +E
Sbjct: 1035 LKNKHESMISE 1045
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/225 (18%), Positives = 93/225 (41%), Gaps = 9/225 (4%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQ-------RLESEIIQ 54
E+ L SK ++ +LE+ + ++ +++ +++E ED++Q RLE +
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1578
Query: 55 TRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKIT 114
+G E + ++ + +R + ++L E LE + K ++ +K K
Sbjct: 1579 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ--RALAAAAKKKLEGDLKDL 1636
Query: 115 NCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETL 174
+ S EE +L++L+A ++EL + ++ K + L
Sbjct: 1637 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1696
Query: 175 KKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARL 219
+++E+L A R+ + L E+ +S + + RL
Sbjct: 1697 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL 1741
Score = 36.2 bits (82), Expect = 0.034
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 34/178 (19%)
Query: 60 EDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQ- 118
E+E KE+ +ER Q+ E E LE+K+ L LQ++L +++ E+
Sbjct: 858 EEEMQAKEDELQKTKERQ-QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916
Query: 119 ---------------SSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQ 163
+ LEE + + QQL+A +++L + E + Q
Sbjct: 917 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL--EEQLEEEEAARQ 974
Query: 164 ALYIKKY--QETLKKIEEEL------------EALFLEREVSKLVSMNPVEKEHTSQN 207
L ++K + +KK+E+E+ E LE +S L + N E+E ++N
Sbjct: 975 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT-NLAEEEEKAKN 1031
Score = 36.2 bits (82), Expect = 0.034
Identities = 32/139 (23%), Positives = 67/139 (48%), Gaps = 5/139 (3%)
Query: 42 EDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITE 101
+D+ +RLE+ I Q +E+E+ E + R +A Q+ E+ + L + T
Sbjct: 1735 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR-KATQQAEQLSNELATERST-AQKNES 1792
Query: 102 LQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCE 161
+Q+L R+++++ + + K + LEA A E+++ + +E T+ +
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Query: 162 DQALYIKKYQETLKKIEEE 180
+ KK +E L ++E+E
Sbjct: 1853 QKD---KKLKEILLQVEDE 1868
Score = 35.4 bits (80), Expect = 0.058
Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 4 SRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED-- 61
S +A + I L +E++ + A + L ++++ K++ + ++ R + E
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSL----KQKDKKLKEILLQVEDERKMAEQYK 1876
Query: 62 EEWEKENRTTMERERALQELEEETARLERKNKTLVHSITE 101
E+ EK N + +R L+E EEE+ R+ + L + E
Sbjct: 1877 EQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1916
Score = 33.9 bits (76), Expect = 0.17
Identities = 36/191 (18%), Positives = 82/191 (42%), Gaps = 10/191 (5%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
+ + + +S++ + L LE D E L +I E + ++ + E E+ ++
Sbjct: 1048 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1107
Query: 61 DEEWEKEN--RTTMERERALQELEEE-------TARLERKNKTLVHSITELQQKLTRKSQ 111
DE +K N + E E + +L+E+ + E++ + L + L+ +L +
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL-EDTL 1166
Query: 112 KITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQ 171
T +Q +E V + L+ E ++ ++ +++A + +Q K+ +
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 172 ETLKKIEEELE 182
L K ++ LE
Sbjct: 1227 ANLDKNKQTLE 1237
Score = 33.5 bits (75), Expect = 0.22
Identities = 48/196 (24%), Positives = 83/196 (42%), Gaps = 38/196 (19%)
Query: 27 IDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETA 86
+DE + ++QE K + E+ E+ E+ R ++ Q LE+E A
Sbjct: 1190 LDEETRSHEAQVQEMRQKHAQAVEELT--------EQLEQFKRAKANLDKNKQTLEKENA 1241
Query: 87 RL--------------ERKNKTLVHSITELQQK----------LTRKSQKITNCEQSSPD 122
L E K K L + ELQ K L K K+ N E S
Sbjct: 1242 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN-EVESVT 1300
Query: 123 GALEETK---VKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLK-KIE 178
G L E + +KL + AS + Q ++ ++++E + +++ + +L+ +++
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 179 EELEA-LFLEREVSKL 193
EE+EA LER +S L
Sbjct: 1361 EEMEAKQNLERHISTL 1376
Score = 32.3 bits (72), Expect = 0.50
Identities = 31/162 (19%), Positives = 75/162 (46%), Gaps = 14/162 (8%)
Query: 74 RERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQ 133
+E +Q E+E + + + + + + EL+QK ++ +++ ++ A E + +
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ--AETELYAEAE 914
Query: 134 QLEASYACQEKELLKVMKEYAFVTQLCEDQALYI----KKYQETLKKIEEELE------- 182
++ A +++EL +++ E + ED+ + KK + + +EE+LE
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974
Query: 183 ALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKI 224
L LE+ V+ + +E E +++ K +L ++I
Sbjct: 975 KLQLEK-VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1015
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 55.1 bits (131), Expect = 7e-08
Identities = 47/212 (22%), Positives = 98/212 (46%), Gaps = 11/212 (5%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
E+ L Q+K+ + LE Q + E DK+ +L++E+ G++ +
Sbjct: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298
Query: 62 EEWE-----KENRTTMERERALQELEEETARLERKNKTLVHSITE----LQQKLTRKSQK 112
E + K+ + + + QEL +E R + T + + E LQ +L + +
Sbjct: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1358
Query: 113 ITNCEQ--SSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKY 170
N E+ S+ + L ++K KLQ ++ E+ + KE +TQ E++A K
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 171 QETLKKIEEELEALFLEREVSKLVSMNPVEKE 202
++T ++++EL+ L ++ + + + N +K+
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1450
Score = 47.4 bits (111), Expect = 1e-05
Identities = 49/226 (21%), Positives = 94/226 (41%), Gaps = 33/226 (14%)
Query: 5 RLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEW 64
+L ++ + +DLE + + A QKL L+ E KI++LE EI+
Sbjct: 940 QLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEIL----------- 988
Query: 65 EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCE--QSSPD 122
++++ +L ++ K L I++L L + +K N ++ +
Sbjct: 989 ---------------VMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 123 GALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELE 182
+ E +V+L++ E S EK K+ + + + D I + + L K EEEL+
Sbjct: 1034 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1093
Query: 183 ALFLEREVSKLVSMNPVEK-----EHTSQNNEGTPTQKTARLFSKK 223
A + N ++K H S E +++ AR ++K
Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEK 1139
Score = 41.6 bits (96), Expect = 8e-04
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 21 ERDTQRIDEANQKLLL----KIQEREDKI----QRLESEIIQTRGLVEDEEWEKENRTTM 72
E D +D NQ+ L+ K Q + D++ + + S+ R E E EKE + +
Sbjct: 1428 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA-L 1486
Query: 73 ERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS--SPDGALEETKV 130
RAL+E E LER NK L + +L + + E+S + + +EE K
Sbjct: 1487 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1546
Query: 131 KLQQLEASYACQEKELLKV-MKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLERE 189
+L++LE E L++ + A Q D ++ +E ++++ +L E E
Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELE 1606
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/191 (21%), Positives = 85/191 (44%), Gaps = 12/191 (6%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRL--ESEIIQTRGLVEDEEWEKENRTTMERERAL 78
E + Q+ E QK +++E E K +L E ++Q + E E + + +
Sbjct: 858 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917
Query: 79 QELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEAS 138
QELEE +E + + +LQ + + +Q++ + E+ LEE + Q+L+
Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ-----LEEEEAARQKLQLE 972
Query: 139 YACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNP 198
E ++ K+ E + +DQ + K ++ L++ +L E E K ++
Sbjct: 973 KVTAEAKIKKLEDEIL----VMDDQNNKLSKERKLLEERISDLTTNLAEEE-EKAKNLTK 1027
Query: 199 VEKEHTSQNNE 209
++ +H S +E
Sbjct: 1028 LKNKHESMISE 1038
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/225 (18%), Positives = 93/225 (41%), Gaps = 9/225 (4%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQ-------RLESEIIQ 54
E+ L SK ++ +LE+ + ++ +++ +++E ED++Q RLE +
Sbjct: 1512 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 55 TRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKIT 114
+G E + ++ + +R + ++L E LE + K ++ +K K
Sbjct: 1572 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ--RALAAAAKKKLEGDLKDL 1629
Query: 115 NCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETL 174
+ S EE +L++L+A ++EL + ++ K + L
Sbjct: 1630 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1689
Query: 175 KKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARL 219
+++E+L A R+ + L E+ +S + + RL
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL 1734
Score = 36.2 bits (82), Expect = 0.034
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 34/178 (19%)
Query: 60 EDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQ- 118
E+E KE+ +ER Q+ E E LE+K+ L LQ++L +++ E+
Sbjct: 851 EEEMQAKEDELQKTKERQ-QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
Query: 119 ---------------SSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQ 163
+ LEE + + QQL+A +++L + E + Q
Sbjct: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL--EEQLEEEEAARQ 967
Query: 164 ALYIKKY--QETLKKIEEEL------------EALFLEREVSKLVSMNPVEKEHTSQN 207
L ++K + +KK+E+E+ E LE +S L + N E+E ++N
Sbjct: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT-NLAEEEEKAKN 1024
Score = 36.2 bits (82), Expect = 0.034
Identities = 32/139 (23%), Positives = 67/139 (48%), Gaps = 5/139 (3%)
Query: 42 EDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITE 101
+D+ +RLE+ I Q +E+E+ E + R +A Q+ E+ + L + T
Sbjct: 1728 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR-KATQQAEQLSNELATERST-AQKNES 1785
Query: 102 LQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCE 161
+Q+L R+++++ + + K + LEA A E+++ + +E T+ +
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Query: 162 DQALYIKKYQETLKKIEEE 180
+ KK +E L ++E+E
Sbjct: 1846 QKD---KKLKEILLQVEDE 1861
Score = 35.4 bits (80), Expect = 0.058
Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 4 SRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED-- 61
S +A + I L +E++ + A + L ++++ K++ + ++ R + E
Sbjct: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSL----KQKDKKLKEILLQVEDERKMAEQYK 1869
Query: 62 EEWEKENRTTMERERALQELEEETARLERKNKTLVHSITE 101
E+ EK N + +R L+E EEE+ R+ + L + E
Sbjct: 1870 EQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1909
Score = 33.9 bits (76), Expect = 0.17
Identities = 36/191 (18%), Positives = 82/191 (42%), Gaps = 10/191 (5%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
+ + + +S++ + L LE D E L +I E + ++ + E E+ ++
Sbjct: 1041 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1100
Query: 61 DEEWEKEN--RTTMERERALQELEEE-------TARLERKNKTLVHSITELQQKLTRKSQ 111
DE +K N + E E + +L+E+ + E++ + L + L+ +L +
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL-EDTL 1159
Query: 112 KITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQ 171
T +Q +E V + L+ E ++ ++ +++A + +Q K+ +
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219
Query: 172 ETLKKIEEELE 182
L K ++ LE
Sbjct: 1220 ANLDKNKQTLE 1230
Score = 33.5 bits (75), Expect = 0.22
Identities = 48/196 (24%), Positives = 83/196 (42%), Gaps = 38/196 (19%)
Query: 27 IDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETA 86
+DE + ++QE K + E+ E+ E+ R ++ Q LE+E A
Sbjct: 1183 LDEETRSHEAQVQEMRQKHAQAVEELT--------EQLEQFKRAKANLDKNKQTLEKENA 1234
Query: 87 RL--------------ERKNKTLVHSITELQQK----------LTRKSQKITNCEQSSPD 122
L E K K L + ELQ K L K K+ N E S
Sbjct: 1235 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN-EVESVT 1293
Query: 123 GALEETK---VKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLK-KIE 178
G L E + +KL + AS + Q ++ ++++E + +++ + +L+ +++
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 179 EELEA-LFLEREVSKL 193
EE+EA LER +S L
Sbjct: 1354 EEMEAKQNLERHISTL 1369
Score = 32.3 bits (72), Expect = 0.50
Identities = 31/162 (19%), Positives = 75/162 (46%), Gaps = 14/162 (8%)
Query: 74 RERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQ 133
+E +Q E+E + + + + + + EL+QK ++ +++ ++ A E + +
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ--AETELYAEAE 907
Query: 134 QLEASYACQEKELLKVMKEYAFVTQLCEDQALYI----KKYQETLKKIEEELE------- 182
++ A +++EL +++ E + ED+ + KK + + +EE+LE
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
Query: 183 ALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKI 224
L LE+ V+ + +E E +++ K +L ++I
Sbjct: 968 KLQLEK-VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1008
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 55.1 bits (131), Expect = 7e-08
Identities = 48/215 (22%), Positives = 97/215 (45%), Gaps = 25/215 (11%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
++ L + + L ++ + + EA+Q+ L +Q EDK+ L I+ V+D
Sbjct: 980 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1039
Query: 62 EEW--EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS 119
E E+E + M+ ERA ++LE + + + + +L +KL +K +I+N +
Sbjct: 1040 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099
Query: 120 SPD---------GALEETKVKLQQLE-------ASYACQEKELLKVMKEYAFVTQLCED- 162
D ++E + ++++LE AS A EK+ + +E +++ E+
Sbjct: 1100 IEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1159
Query: 163 ------QALYIKKYQETLKKIEEELEALFLEREVS 191
Q KK + +K+ +LE L+ E +
Sbjct: 1160 GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEAT 1194
Score = 43.1 bits (100), Expect = 3e-04
Identities = 47/198 (23%), Positives = 90/198 (45%), Gaps = 20/198 (10%)
Query: 2 EISRLAQSKRNIIS-LNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
E SR K ++S L+ + TQ+I+E ++L +I+ + L+S L
Sbjct: 1292 EFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLL-- 1349
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKT-LVHSITELQQKLTRKSQKITNCEQ- 118
E++E+E + E +RAL + E A+ K +T + EL++ + +Q++ E+
Sbjct: 1350 REQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEH 1409
Query: 119 ----SSPDGALEETKVKLQ-----------QLEASYACQEKELLKVMKEYAFVTQLCEDQ 163
++ +LE+TK +LQ + A+ A +K+ K A Q CE+
Sbjct: 1410 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEET 1469
Query: 164 ALYIKKYQETLKKIEEEL 181
++ Q+ + + EL
Sbjct: 1470 HAELEASQKEARSLGTEL 1487
Score = 38.9 bits (89), Expect = 0.005
Identities = 42/187 (22%), Positives = 87/187 (46%), Gaps = 17/187 (9%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
MEI LA + + +LE+ + +++ L +++ +E++ QRL +++ RG ++
Sbjct: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQ----LSELKSKEEEQQRLINDLTAQRGRLQ 1287
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKL---TRKSQKITNCE 117
E + E R L E E ++L R + I EL+++L + + +
Sbjct: 1288 TE--------SGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHAL 1339
Query: 118 QSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYA-FVTQLCEDQALYIKKYQETLKK 176
QSS + + + ++ + S A ++ L K E A + T+ D ++ +E KK
Sbjct: 1340 QSSRHDC-DLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
Query: 177 IEEELEA 183
+ + L+A
Sbjct: 1399 LAQRLQA 1405
Score = 37.0 bits (84), Expect = 0.020
Identities = 52/232 (22%), Positives = 94/232 (40%), Gaps = 37/232 (15%)
Query: 6 LAQSKRNIISLNMDLERDTQRIDEANQKL----LLKIQEREDKI-----------QRLES 50
+ + + N++ ++ R T E ++K+ LL ER + ++LE+
Sbjct: 1679 MVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLET 1738
Query: 51 EIIQTRGLVED------EEWEKENRTTMERERALQELEEE---TARLERKNKTLVHSITE 101
+I Q +G +ED EK + + +EL++E +A LER K + ++ +
Sbjct: 1739 DISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKD 1798
Query: 102 LQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCE 161
LQ +L Q AL+ K ++Q+LEA E E+ K A +
Sbjct: 1799 LQLRLDEAEQL-----------ALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 162 DQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPT 213
+K+ T + E+ L L+ V KL + K + E + T
Sbjct: 1848 KHERRVKEL--TYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNT 1897
Score = 36.2 bits (82), Expect = 0.034
Identities = 45/171 (26%), Positives = 82/171 (47%), Gaps = 33/171 (19%)
Query: 58 LVEDEEWEKENRTTMERERALQELEEETARLERKNK-------TLVHSITELQQKLTRKS 110
L++ E EKE T E Q++++E A+ E K K TL+ +LQ ++ ++
Sbjct: 845 LLKSAETEKEMATMKEE---FQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEA 901
Query: 111 QKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKY 170
+ + + E+ L +TK+ QLEA +KE VT+ ED+ +
Sbjct: 902 EGLADAEERCDQ--LIKTKI---QLEAK-----------IKE---VTERAEDEEEINAEL 942
Query: 171 QETLKKIEEELEALFLEREVSKL-VSMNPVEKE-HTSQNNEGTPTQKTARL 219
+K+E+E L++++ L +++ VEKE H ++N T++ A L
Sbjct: 943 TAKKRKLEDECSE--LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 991
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 55.1 bits (131), Expect = 7e-08
Identities = 48/215 (22%), Positives = 97/215 (45%), Gaps = 25/215 (11%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
++ L + + L ++ + + EA+Q+ L +Q EDK+ L I+ V+D
Sbjct: 980 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1039
Query: 62 EEW--EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS 119
E E+E + M+ ERA ++LE + + + + +L +KL +K +I+N +
Sbjct: 1040 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099
Query: 120 SPD---------GALEETKVKLQQLE-------ASYACQEKELLKVMKEYAFVTQLCED- 162
D ++E + ++++LE AS A EK+ + +E +++ E+
Sbjct: 1100 IEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1159
Query: 163 ------QALYIKKYQETLKKIEEELEALFLEREVS 191
Q KK + +K+ +LE L+ E +
Sbjct: 1160 GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEAT 1194
Score = 43.1 bits (100), Expect = 3e-04
Identities = 47/198 (23%), Positives = 90/198 (45%), Gaps = 20/198 (10%)
Query: 2 EISRLAQSKRNIIS-LNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
E SR K ++S L+ + TQ+I+E ++L +I+ + L+S L
Sbjct: 1292 EFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLL-- 1349
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKT-LVHSITELQQKLTRKSQKITNCEQ- 118
E++E+E + E +RAL + E A+ K +T + EL++ + +Q++ E+
Sbjct: 1350 REQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEH 1409
Query: 119 ----SSPDGALEETKVKLQ-----------QLEASYACQEKELLKVMKEYAFVTQLCEDQ 163
++ +LE+TK +LQ + A+ A +K+ K A Q CE+
Sbjct: 1410 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEET 1469
Query: 164 ALYIKKYQETLKKIEEEL 181
++ Q+ + + EL
Sbjct: 1470 HAELEASQKEARSLGTEL 1487
Score = 38.9 bits (89), Expect = 0.005
Identities = 42/187 (22%), Positives = 87/187 (46%), Gaps = 17/187 (9%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
MEI LA + + +LE+ + +++ L +++ +E++ QRL +++ RG ++
Sbjct: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQ----LSELKSKEEEQQRLINDLTAQRGRLQ 1287
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKL---TRKSQKITNCE 117
E + E R L E E ++L R + I EL+++L + + +
Sbjct: 1288 TE--------SGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHAL 1339
Query: 118 QSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYA-FVTQLCEDQALYIKKYQETLKK 176
QSS + + + ++ + S A ++ L K E A + T+ D ++ +E KK
Sbjct: 1340 QSSRHDC-DLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
Query: 177 IEEELEA 183
+ + L+A
Sbjct: 1399 LAQRLQA 1405
Score = 37.0 bits (84), Expect = 0.020
Identities = 52/232 (22%), Positives = 94/232 (40%), Gaps = 37/232 (15%)
Query: 6 LAQSKRNIISLNMDLERDTQRIDEANQKL----LLKIQEREDKI-----------QRLES 50
+ + + N++ ++ R T E ++K+ LL ER + ++LE+
Sbjct: 1679 MVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLET 1738
Query: 51 EIIQTRGLVED------EEWEKENRTTMERERALQELEEE---TARLERKNKTLVHSITE 101
+I Q +G +ED EK + + +EL++E +A LER K + ++ +
Sbjct: 1739 DISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKD 1798
Query: 102 LQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCE 161
LQ +L Q AL+ K ++Q+LEA E E+ K A +
Sbjct: 1799 LQLRLDEAEQL-----------ALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 162 DQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPT 213
+K+ T + E+ L L+ V KL + K + E + T
Sbjct: 1848 KHERRVKEL--TYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNT 1897
Score = 36.2 bits (82), Expect = 0.034
Identities = 45/171 (26%), Positives = 82/171 (47%), Gaps = 33/171 (19%)
Query: 58 LVEDEEWEKENRTTMERERALQELEEETARLERKNK-------TLVHSITELQQKLTRKS 110
L++ E EKE T E Q++++E A+ E K K TL+ +LQ ++ ++
Sbjct: 845 LLKSAETEKEMATMKEE---FQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEA 901
Query: 111 QKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKY 170
+ + + E+ L +TK+ QLEA +KE VT+ ED+ +
Sbjct: 902 EGLADAEERCDQ--LIKTKI---QLEAK-----------IKE---VTERAEDEEEINAEL 942
Query: 171 QETLKKIEEELEALFLEREVSKL-VSMNPVEKE-HTSQNNEGTPTQKTARL 219
+K+E+E L++++ L +++ VEKE H ++N T++ A L
Sbjct: 943 TAKKRKLEDECSE--LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 991
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 54.7 bits (130), Expect = 9e-08
Identities = 38/137 (27%), Positives = 72/137 (52%), Gaps = 8/137 (5%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
E+ R + R + + D E + ++E Q+ K+QE+E+KIQR E +I + E+
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ----EE 483
Query: 62 EEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS-- 119
+ W +E +++E + E EE+ R E K + E ++K+ R+ +K+ E
Sbjct: 484 KTWRQEK--LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
Query: 120 SPDGALEETKVKLQQLE 136
+ ++E +V+LQ+LE
Sbjct: 542 QQEEKMQEQEVRLQELE 558
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/195 (22%), Positives = 93/195 (47%), Gaps = 11/195 (5%)
Query: 5 RLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEW 64
++ + I ++ R ++I E +K K+ +E K++ + +I + E+E W
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ----EEEMW 430
Query: 65 EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSS--PD 122
+E + E E +Q+ EE+ +E K + + E ++K+ R+ +KI E+ + +
Sbjct: 431 RQEEKIR-ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 123 GALEETKVKLQQLEASYACQEK--ELLKVMKEYAFVTQLCED--QALYIKKYQETLKKIE 178
L++ + +Q E + +EK E + M+E Q E+ + ++ +Q+ K E
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
Query: 179 EELEALFLEREVSKL 193
+E+ LE + KL
Sbjct: 550 QEVRLQELEERLGKL 564
Score = 41.6 bits (96), Expect = 8e-04
Identities = 53/233 (22%), Positives = 106/233 (45%), Gaps = 33/233 (14%)
Query: 5 RLAQSKRNIISLNM-DLERDTQRIDEANQKLLLKIQEREDKIQRLESEI----IQTRGLV 59
RL +S+++ I LN+ DL+R +R +LLL Q+ + + RL E+ + + V
Sbjct: 228 RLVESEKSEIQLNVKDLKRKLERA-----QLLLPQQQLQVEADRLGKELQSVSAKLQAQV 282
Query: 60 EDEE-------------WEKENRTT------MERERALQELEEETARLERKNKTLVHSIT 100
E+ E W +E + E+E ++E EE+ R E K I
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342
Query: 101 ELQQKLTRKSQKITNCEQS--SPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQ 158
E + K+ R+ +KI E+ + + + K+++ + QE+E+ + ++ +
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 159 LCEDQA-LYIKKYQETLKKIEEELEALFLERE-VSKLVSMNPVEKEHTSQNNE 209
+++ KK +E +KI E+ E ++ + E + +L M ++E + E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Score = 38.1 bits (87), Expect = 0.009
Identities = 37/127 (29%), Positives = 64/127 (50%), Gaps = 23/127 (18%)
Query: 37 KIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTL- 95
K+QE+E+K+QR E ++ + E W++E + E+E LQELEE +L +K + L
Sbjct: 518 KMQEQEEKMQRQEEKMREQ----EVRLWQQEEKM-QEQEVRLQELEERLGKLGQKAELLG 572
Query: 96 ----------VHSITELQQKLTRKSQKITNCEQSSPD--GALEETKVKLQQL----EASY 139
+ ++T + Q + KSQ+ + +Q G L++ QQL EA
Sbjct: 573 GAGRESGSQRLPTLTPILQ-VELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALP 631
Query: 140 ACQEKEL 146
+C ++L
Sbjct: 632 SCSSRKL 638
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 54.7 bits (130), Expect = 9e-08
Identities = 38/137 (27%), Positives = 72/137 (52%), Gaps = 8/137 (5%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
E+ R + R + + D E + ++E Q+ K+QE+E+KIQR E +I + E+
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ----EE 483
Query: 62 EEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS-- 119
+ W +E +++E + E EE+ R E K + E ++K+ R+ +K+ E
Sbjct: 484 KTWRQEK--LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
Query: 120 SPDGALEETKVKLQQLE 136
+ ++E +V+LQ+LE
Sbjct: 542 QQEEKMQEQEVRLQELE 558
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/195 (22%), Positives = 93/195 (47%), Gaps = 11/195 (5%)
Query: 5 RLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEW 64
++ + I ++ R ++I E +K K+ +E K++ + +I + E+E W
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ----EEEMW 430
Query: 65 EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSS--PD 122
+E + E E +Q+ EE+ +E K + + E ++K+ R+ +KI E+ + +
Sbjct: 431 RQEEKIR-ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 123 GALEETKVKLQQLEASYACQEK--ELLKVMKEYAFVTQLCED--QALYIKKYQETLKKIE 178
L++ + +Q E + +EK E + M+E Q E+ + ++ +Q+ K E
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
Query: 179 EELEALFLEREVSKL 193
+E+ LE + KL
Sbjct: 550 QEVRLQELEERLGKL 564
Score = 41.6 bits (96), Expect = 8e-04
Identities = 53/233 (22%), Positives = 106/233 (45%), Gaps = 33/233 (14%)
Query: 5 RLAQSKRNIISLNM-DLERDTQRIDEANQKLLLKIQEREDKIQRLESEI----IQTRGLV 59
RL +S+++ I LN+ DL+R +R +LLL Q+ + + RL E+ + + V
Sbjct: 228 RLVESEKSEIQLNVKDLKRKLERA-----QLLLPQQQLQVEADRLGKELQSVSAKLQAQV 282
Query: 60 EDEE-------------WEKENRTT------MERERALQELEEETARLERKNKTLVHSIT 100
E+ E W +E + E+E ++E EE+ R E K I
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342
Query: 101 ELQQKLTRKSQKITNCEQS--SPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQ 158
E + K+ R+ +KI E+ + + + K+++ + QE+E+ + ++ +
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 159 LCEDQA-LYIKKYQETLKKIEEELEALFLERE-VSKLVSMNPVEKEHTSQNNE 209
+++ KK +E +KI E+ E ++ + E + +L M ++E + E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Score = 38.1 bits (87), Expect = 0.009
Identities = 37/127 (29%), Positives = 64/127 (50%), Gaps = 23/127 (18%)
Query: 37 KIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTL- 95
K+QE+E+K+QR E ++ + E W++E + E+E LQELEE +L +K + L
Sbjct: 518 KMQEQEEKMQRQEEKMREQ----EVRLWQQEEKM-QEQEVRLQELEERLGKLGQKAELLG 572
Query: 96 ----------VHSITELQQKLTRKSQKITNCEQSSPD--GALEETKVKLQQL----EASY 139
+ ++T + Q + KSQ+ + +Q G L++ QQL EA
Sbjct: 573 GAGRESGSQRLPTLTPILQ-VELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALP 631
Query: 140 ACQEKEL 146
+C ++L
Sbjct: 632 SCSSRKL 638
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 52.8 bits (125), Expect = 4e-07
Identities = 46/215 (21%), Positives = 96/215 (44%), Gaps = 25/215 (11%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
++ L + + L ++ + + EA+Q+ L +Q EDK+ L I+ V+D
Sbjct: 978 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1037
Query: 62 EE--WEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS 119
E E+E + M+ ERA ++LE + + + + +L +KL +K +++ +
Sbjct: 1038 LEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSK 1097
Query: 120 SPD---------GALEETKVKLQQLE-------ASYACQEKELLKVMKEYAFVTQLCED- 162
D ++E + ++++LE AS A EK+ + +E +++ E+
Sbjct: 1098 IEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1157
Query: 163 ------QALYIKKYQETLKKIEEELEALFLEREVS 191
Q KK + +K+ +LE L+ E +
Sbjct: 1158 GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEAT 1192
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/198 (23%), Positives = 90/198 (45%), Gaps = 20/198 (10%)
Query: 2 EISRLAQSKRNIIS-LNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
E SR K ++S L+ + TQ+I+E ++L +I+ + L+S L
Sbjct: 1290 EYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLL-- 1347
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKT-LVHSITELQQKLTRKSQKITNCEQ- 118
E++E+E E +RA+ + E A+ K +T + EL++ + +Q++ + E+
Sbjct: 1348 REQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEH 1407
Query: 119 ----SSPDGALEETKVKLQ-----------QLEASYACQEKELLKVMKEYAFVTQLCEDQ 163
++ +LE+TK +LQ + A+ A +K+ K A Q CE+
Sbjct: 1408 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEET 1467
Query: 164 ALYIKKYQETLKKIEEEL 181
++ Q+ + + EL
Sbjct: 1468 HAELEASQKESRSLSTEL 1485
Score = 38.1 bits (87), Expect = 0.009
Identities = 40/209 (19%), Positives = 93/209 (44%), Gaps = 35/209 (16%)
Query: 6 LAQSKRNIISLNMDLERDTQRIDEANQKL----LLKIQEREDKI-----------QRLES 50
+ + + N++ ++ R T E ++K+ LL ER + ++LE+
Sbjct: 1677 MVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLET 1736
Query: 51 EIIQTRGLVED------EEWEKENRTTMERERALQELEEE---TARLERKNKTLVHSITE 101
+I Q +G +ED EK + + +EL++E +A LER K L ++ +
Sbjct: 1737 DISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1796
Query: 102 LQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMK-------EYA 154
LQ +L Q + +++ + ++++LE ++K ++ +K +
Sbjct: 1797 LQHRLDEAEQLALKGGKKQ----IQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVK 1852
Query: 155 FVTQLCEDQALYIKKYQETLKKIEEELEA 183
+T E+ I + Q+ + K++ ++++
Sbjct: 1853 ELTYQTEEDRKNILRLQDLVDKLQAKVKS 1881
Score = 35.8 bits (81), Expect = 0.045
Identities = 45/168 (26%), Positives = 80/168 (47%), Gaps = 27/168 (16%)
Query: 58 LVEDEEWEKENRTTMER-ERALQELEEETAR---LERKNKTLVHSITELQQKLTRKSQKI 113
L++ E EKE E E+ +EL + A+ LE K TL+ +LQ ++ ++ +
Sbjct: 843 LLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSL 902
Query: 114 TNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQET 173
+ E+ L +TK+ QLEA +KE VT+ ED+ +
Sbjct: 903 ADAEERCDQ--LIKTKI---QLEAK-----------IKE---VTERAEDEEEINAELTAK 943
Query: 174 LKKIEEELEALFLEREVSKL-VSMNPVEKE-HTSQNNEGTPTQKTARL 219
+K+E+E L++++ L +++ VEKE H ++N T++ A L
Sbjct: 944 KRKLEDECSE--LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 989
Score = 35.4 bits (80), Expect = 0.058
Identities = 42/194 (21%), Positives = 84/194 (43%), Gaps = 22/194 (11%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
MEI LA + + +LE+ + +++ L +I+ +E++ QRL +++ R ++
Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRALEDQ----LSEIKTKEEEQQRLINDLTAQRARLQ 1285
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKL---TRKSQKITNCE 117
E + E R L E + ++L R + I EL+++L + + +
Sbjct: 1286 TE--------SGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHAL 1337
Query: 118 QSSPDGA------LEETKVKLQQLEASYACQEKELLKVMKEY-AFVTQLCEDQALYIKKY 170
QSS EE + +L+ + + E+ + +Y Q E+ KK
Sbjct: 1338 QSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1397
Query: 171 QETLKKIEEELEAL 184
+ L+ EE +EA+
Sbjct: 1398 AQRLQDAEEHVEAV 1411
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 52.4 bits (124), Expect = 5e-07
Identities = 36/165 (21%), Positives = 83/165 (50%), Gaps = 4/165 (2%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWE--KENRTTMERERAL 78
E + R E Q+ K+ +E+KI+ E +I + +++++E + ++ E+E +
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 79 QELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS--SPDGALEETKVKLQQLE 136
QE EE+ R E K + I E ++K+ + + + E+ +G + E + K+Q+ E
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQE 487
Query: 137 ASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEEL 181
QE+++ + K+ + +Q +++ +E + + EE++
Sbjct: 488 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 532
Score = 45.4 bits (106), Expect = 6e-05
Identities = 34/158 (21%), Positives = 81/158 (51%), Gaps = 14/158 (8%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWE--KENRTTMERERAL 78
E + Q +E ++ KI+E+E KI+ E +I + +++++E + ++ E+E +
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483
Query: 79 QELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEAS 138
QE EE+ R E K I E ++K+ + +KI E+ ++E + K+ + E
Sbjct: 484 QEQEEKMRRQEEK-------IREQEKKIREQEEKIREQEE-----MMQEQEEKMWEQEEK 531
Query: 139 YACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKK 176
QE+++ + ++ + +Q + +++ +E +++
Sbjct: 532 MCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/179 (23%), Positives = 86/179 (48%), Gaps = 18/179 (10%)
Query: 25 QRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEE---WEKENRTT------MERE 75
++I E +K+ + + RE + +R E E I+ + +++E W +E + E+E
Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 76 RALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQL 135
+QE EE+ E K + E ++K+ R+ +KI E+ + E + K+++
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK-----IREQEEKIREQ 458
Query: 136 EASYACQEKEL----LKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREV 190
E QE+++ K+ ++ A + + E +K +E KKI E+ E + + E+
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517
Score = 42.0 bits (97), Expect = 6e-04
Identities = 37/151 (24%), Positives = 76/151 (50%), Gaps = 11/151 (7%)
Query: 37 KIQEREDKIQRLESEIIQTRGLVEDEE---WEKENRTTMERERALQELEEETARLERKNK 93
KIQERE+KIQ E +I + + +E WEKE + + E + E EE+ LE K
Sbjct: 296 KIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM-MWEKEEKIRELEEK-- 352
Query: 94 TLVHSITEL--QQKLTRKSQKITNCEQSSPDGA-LEETKVKLQQLEASYACQEKELLKVM 150
+H ++ Q++ ++ +KI E+ A + + K+++ E QE+ + +
Sbjct: 353 --MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQE 410
Query: 151 KEYAFVTQLCEDQALYIKKYQETLKKIEEEL 181
++ + +Q +++ +E +++ EE++
Sbjct: 411 EKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI 441
Score = 41.6 bits (96), Expect = 8e-04
Identities = 50/216 (23%), Positives = 97/216 (44%), Gaps = 44/216 (20%)
Query: 5 RLAQSKRNIISLNM-DLERDTQRIDEANQKLLLKIQEREDKIQRLESEI----IQTRGLV 59
+L +S+++ I LN+ +L+R +R KLLL Q+ + + L E+ + + V
Sbjct: 219 QLVESEKSEIQLNVKELKRKLERA-----KLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273
Query: 60 EDEE-------------WEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKL 106
E+ E W +E + ERE +QE EE+ E K + + E ++K+
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKI-QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKM 332
Query: 107 TR-------KSQKITNCEQ---------SSPDGALEETKV----KLQQLEASYACQEKEL 146
R K +KI E+ + EE K+ K Q+ EA QE+++
Sbjct: 333 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 392
Query: 147 LKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELE 182
+ ++ ++ ++Q + + +E + + EEE++
Sbjct: 393 REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428
Score = 31.6 bits (70), Expect = 0.84
Identities = 48/223 (21%), Positives = 92/223 (41%), Gaps = 23/223 (10%)
Query: 3 ISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDE 62
+ +L R++IS D + +++A L + ++ K R E+ + R + E
Sbjct: 141 VKQLEGEARDLISRLHDSWKFAGELEQA----LSAVATQKKKADRYIEELTKERDALSLE 196
Query: 63 EWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPD 122
+ R T+ E EL+E+ A+L+ K + + +E+Q + +K+ + P
Sbjct: 197 LY----RNTITDE----ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ 248
Query: 123 GAL----EETKVKLQQLEASYACQ--EKELLKVMKEYAFVTQLCEDQALYIKKYQETLKK 176
L + +LQ + A Q E EL + + Q E +K QE +K
Sbjct: 249 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ-----QQEEKMWRQEEKIQEREEK 303
Query: 177 IEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARL 219
I+E+ E + + E + EKE + E +K ++
Sbjct: 304 IQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
[Homo sapiens]
Length = 969
Score = 52.4 bits (124), Expect = 5e-07
Identities = 66/241 (27%), Positives = 107/241 (44%), Gaps = 20/241 (8%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE- 60
E SRLA+++ ++ ++ E++ E ++KL + ED T L +
Sbjct: 114 EESRLAKNEAARMAALVEAEKECNL--ELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQR 171
Query: 61 DEEWEKENRTTMERERALQELEEETARL----ERKNKTLVHSITE---LQQKLTRKSQKI 113
D+ E+ N++ +ER +++L E +L E V +TE QQKL I
Sbjct: 172 DKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTI 231
Query: 114 TNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQET 173
T +QS D L E + K+QQ EA+ +++L ++ E + + Q I+ +ET
Sbjct: 232 T--QQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKET 289
Query: 174 LKKIEEELEALFLEREVSKLVSMNPVEKEHTSQ-----NNEGT-PTQKTARL--FSKKIF 225
LK E E E L+ E E H SQ ++EGT P Q+ L +F
Sbjct: 290 LKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALF 349
Query: 226 C 226
C
Sbjct: 350 C 350
Score = 32.7 bits (73), Expect = 0.38
Identities = 29/131 (22%), Positives = 66/131 (50%), Gaps = 8/131 (6%)
Query: 75 ERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQ 134
E A E E++ + N+ L ++ +LQ++L KSQ++ E + + + +Q
Sbjct: 380 EAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWE-AEKYNEIRTQEQNIQH 438
Query: 135 LEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEEL--EALFLEREV-S 191
L S + +E ++++E+ + Q ++ ++ + L+K+ + + +A+ LER +
Sbjct: 439 LNHSLSHKE----QLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDE 494
Query: 192 KLVSMNPVEKE 202
K ++ EKE
Sbjct: 495 KFSALEEKEKE 505
Score = 32.7 bits (73), Expect = 0.38
Identities = 28/127 (22%), Positives = 61/127 (48%), Gaps = 3/127 (2%)
Query: 22 RDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQEL 81
+ Q + +A Q+L ++Q + +++ E+E +++ + N + +E+ LQE
Sbjct: 395 KHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIR-TQEQNIQHLNHSLSHKEQLLQEF 453
Query: 82 EEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPD--GALEETKVKLQQLEASY 139
E + +KTL + L++ R K E++ + ALEE + +L+QL +
Sbjct: 454 RELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAV 513
Query: 140 ACQEKEL 146
++ +L
Sbjct: 514 RERDHDL 520
Score = 32.3 bits (72), Expect = 0.50
Identities = 28/128 (21%), Positives = 61/128 (47%), Gaps = 14/128 (10%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQ----EREDKIQRLESEIIQTR 56
+E+ +L+ + +N+ L ++E R + + ++ ++Q +R +++ L + ++
Sbjct: 546 LEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKL 605
Query: 57 GLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNC 116
G + E E+ + +ER LQ+L L +NK ++ E+Q L Q ++
Sbjct: 606 GPGQSEIAEELCQRLQRKERMLQDL------LSDRNKQVLEHEMEIQGLL----QSVSTR 655
Query: 117 EQSSPDGA 124
EQ S A
Sbjct: 656 EQESQAAA 663
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
[Homo sapiens]
Length = 2346
Score = 52.4 bits (124), Expect = 5e-07
Identities = 66/241 (27%), Positives = 107/241 (44%), Gaps = 20/241 (8%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE- 60
E SRLA+++ ++ ++ E++ E ++KL + ED T L +
Sbjct: 114 EESRLAKNEAARMAALVEAEKECNL--ELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQR 171
Query: 61 DEEWEKENRTTMERERALQELEEETARL----ERKNKTLVHSITE---LQQKLTRKSQKI 113
D+ E+ N++ +ER +++L E +L E V +TE QQKL I
Sbjct: 172 DKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTI 231
Query: 114 TNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQET 173
T +QS D L E + K+QQ EA+ +++L ++ E + + Q I+ +ET
Sbjct: 232 T--QQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKET 289
Query: 174 LKKIEEELEALFLEREVSKLVSMNPVEKEHTSQ-----NNEGT-PTQKTARL--FSKKIF 225
LK E E E L+ E E H SQ ++EGT P Q+ L +F
Sbjct: 290 LKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALF 349
Query: 226 C 226
C
Sbjct: 350 C 350
Score = 32.7 bits (73), Expect = 0.38
Identities = 29/131 (22%), Positives = 66/131 (50%), Gaps = 8/131 (6%)
Query: 75 ERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQ 134
E A E E++ + N+ L ++ +LQ++L KSQ++ E + + + +Q
Sbjct: 380 EAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWE-AEKYNEIRTQEQNIQH 438
Query: 135 LEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEEL--EALFLEREV-S 191
L S + +E ++++E+ + Q ++ ++ + L+K+ + + +A+ LER +
Sbjct: 439 LNHSLSHKE----QLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDE 494
Query: 192 KLVSMNPVEKE 202
K ++ EKE
Sbjct: 495 KFSALEEKEKE 505
Score = 32.7 bits (73), Expect = 0.38
Identities = 28/127 (22%), Positives = 61/127 (48%), Gaps = 3/127 (2%)
Query: 22 RDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQEL 81
+ Q + +A Q+L ++Q + +++ E+E +++ + N + +E+ LQE
Sbjct: 395 KHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIR-TQEQNIQHLNHSLSHKEQLLQEF 453
Query: 82 EEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPD--GALEETKVKLQQLEASY 139
E + +KTL + L++ R K E++ + ALEE + +L+QL +
Sbjct: 454 RELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAV 513
Query: 140 ACQEKEL 146
++ +L
Sbjct: 514 RERDHDL 520
Score = 32.3 bits (72), Expect = 0.50
Identities = 28/128 (21%), Positives = 61/128 (47%), Gaps = 14/128 (10%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQ----EREDKIQRLESEIIQTR 56
+E+ +L+ + +N+ L ++E R + + ++ ++Q +R +++ L + ++
Sbjct: 546 LEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKL 605
Query: 57 GLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNC 116
G + E E+ + +ER LQ+L L +NK ++ E+Q L Q ++
Sbjct: 606 GPGQSEIAEELCQRLQRKERMLQDL------LSDRNKQVLEHEMEIQGLL----QSVSTR 655
Query: 117 EQSSPDGA 124
EQ S A
Sbjct: 656 EQESQAAA 663
Score = 31.6 bits (70), Expect = 0.84
Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 41 REDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSIT 100
RED +RL++++ +E E + LQELE+E + + + L+ +
Sbjct: 1908 REDN-RRLQAQLSHV-SREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLR 1965
Query: 101 ELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELL 147
E QQ++ ++ + +++ D L+ V LQQ C+EK+ L
Sbjct: 1966 EKQQEVLHFREERLSLQEN--DSRLQHKLVLLQQ-----QCEEKQQL 2005
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 52.4 bits (124), Expect = 5e-07
Identities = 48/222 (21%), Positives = 104/222 (46%), Gaps = 20/222 (9%)
Query: 5 RLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDK---IQRLESEIIQTRGLVED 61
+ AQ I + + + + A QK+ +E + IQ L++E++Q G+ +
Sbjct: 164 KAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDV 223
Query: 62 EEWEKE--------NRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKI 113
+KE + T+ERER ++L++E +L+ + + +I++L+ +L + Q++
Sbjct: 224 AVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEV 283
Query: 114 TNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQET 173
Q L++ K + +L + LLK ++Y + + ++++ K Q T
Sbjct: 284 AVYVQE-----LQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQAT 338
Query: 174 LKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQK 215
L +++L+ L+ +S S + + H + +G TQK
Sbjct: 339 LH--QKDLDCQQLQSRLS--ASETSLHRIHVELSEKGEATQK 376
Score = 50.1 bits (118), Expect = 2e-06
Identities = 42/217 (19%), Positives = 101/217 (46%), Gaps = 16/217 (7%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
E+S + +++ + L++ + ++ +L +I + K+ E ++ + G +++
Sbjct: 380 ELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKE 439
Query: 62 EEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSP 121
+ + + M++E+ + +L+ + +RLE + K V + TELQ +L + Q +
Sbjct: 440 QR-QLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQ-----QHQEQ 493
Query: 122 DGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEEL 181
+ T KL++ + +L +V+++ Q ++ ++K +E + +E+E
Sbjct: 494 QALQQSTTAKLRE-------AQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKER 546
Query: 182 EALFLEREVSK---LVSMNPVEKEHTSQNNEGTPTQK 215
E L+ + + + V EK HT Q T+K
Sbjct: 547 EDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEK 583
Score = 46.6 bits (109), Expect = 3e-05
Identities = 47/197 (23%), Positives = 96/197 (48%), Gaps = 22/197 (11%)
Query: 2 EISRLAQSKRNIIS-LNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
E+S+ + ++ I+S +DL++ ++ ++ QKL QE E +I + + E + ++
Sbjct: 769 ELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTK--QEEEKQILKQDFETLSQETKIQ 826
Query: 61 DEEWEKENRTT--------MERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQK 112
EE +TT ME+E + EL +L + + +L +S +E +++ +
Sbjct: 827 HEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAA 886
Query: 113 ITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKE-----YAFVTQLCEDQALYI 167
I + E++ +E K +LQ + ++KEL K +++ + +L Q I
Sbjct: 887 ILDLEKT-----CKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLI 941
Query: 168 KKYQETLKKIEEELEAL 184
+ Q TLK+ E+E + L
Sbjct: 942 QA-QNTLKQNEKEEQQL 957
Score = 45.8 bits (107), Expect = 4e-05
Identities = 50/246 (20%), Positives = 106/246 (43%), Gaps = 21/246 (8%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
+++SRL + + ++ + +L+ + + +Q+ Q K++ ++++ Q +
Sbjct: 460 LKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIG 519
Query: 61 DEEWE-----------KENRTTMERERA-----LQELEEETA---RLERKNKTLVHSITE 101
D++ + KEN + +E+ER +Q E ETA +L+ KN TL +T+
Sbjct: 520 DKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQ 579
Query: 102 LQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCE 161
L +KL +S+ +++ D ++E K L+ + E + ++ + +
Sbjct: 580 LTEKLKNQSESHKQAQENLHD-QVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVS 638
Query: 162 DQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTP-TQKTARLF 220
+ IK E L E A + + + N ++ + N T Q TA+L
Sbjct: 639 QLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQ 698
Query: 221 SKKIFC 226
K+ C
Sbjct: 699 DKQEHC 704
Score = 43.1 bits (100), Expect = 3e-04
Identities = 43/207 (20%), Positives = 102/207 (49%), Gaps = 5/207 (2%)
Query: 13 IISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTM 72
+++ DL+ +++ A + L+ + ++ +L E+ + +E + +KE +
Sbjct: 1042 LLATRQDLKSVEEKLSLAQEDLISNRNQIGNQ-NKLIQELKTAKATLEQDSAKKEQQL-Q 1099
Query: 73 ERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKL 132
ER +ALQ++++E + E++ + E+++ R+ ++IT + LE K ++
Sbjct: 1100 ERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIK-EI 1158
Query: 133 QQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSK 192
L+ + ++ L++ + + E + + ++ +KK EEEL+ F+E+E +K
Sbjct: 1159 TNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKE-AK 1217
Query: 193 LVSMNPVEKEHTSQNNEGTPTQKTARL 219
L S EKE + +E + T ++
Sbjct: 1218 LHS-EIKEKEVGMKKHEENEAKLTMQI 1243
Score = 37.7 bits (86), Expect = 0.012
Identities = 43/193 (22%), Positives = 87/193 (45%), Gaps = 30/193 (15%)
Query: 19 DLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKEN---------- 68
D +++ +I ++ K+Q++++ +LES + + + E + E
Sbjct: 678 DKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEA 737
Query: 69 ---RTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKI--TNCEQSSPDG 123
+E+ALQ+L+++ + N L TEL ++L + + + T +
Sbjct: 738 DSLEVKASKEQALQDLQQQ----RQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSE 793
Query: 124 ALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQET----LKKIEE 179
ALE K KL + E +EK++LK +++ ++Q + Q + +T L+K++
Sbjct: 794 ALESIKQKLTKQE-----EEKQILK--QDFETLSQETKIQHEELNNRIQTTVTELQKVKM 846
Query: 180 ELEALFLEREVSK 192
E EAL E K
Sbjct: 847 EKEALMTELSTVK 859
Score = 33.5 bits (75), Expect = 0.22
Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 15/201 (7%)
Query: 27 IDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETA 86
++E N +L E ++K+ +L+ +I L+ E K T +R L+
Sbjct: 623 VNELNSQL----NESKEKVSQLDIQIKAKTELLLSAEAAK----TAQRADLQNHLDTAQN 674
Query: 87 RLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKEL 146
L+ K + L T+L Q + K +C Q + L+E K K LE E ++
Sbjct: 675 ALQDKQQELNKITTQLDQVTAKLQDKQEHCSQL--ESHLKEYKEKYLSLEQKTEELEGQI 732
Query: 147 LKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREV---SKLVSMNPVEKEH 203
K+ + + + ++QAL + Q L + EL A L +++ ++VS ++ +
Sbjct: 733 KKLEAD-SLEVKASKEQALQDLQQQRQL-NTDLELRATELSKQLEMEKEIVSSTRLDLQK 790
Query: 204 TSQNNEGTPTQKTARLFSKKI 224
S+ E + T + K+I
Sbjct: 791 KSEALESIKQKLTKQEEEKQI 811
Score = 33.1 bits (74), Expect = 0.29
Identities = 43/211 (20%), Positives = 88/211 (41%), Gaps = 30/211 (14%)
Query: 8 QSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQT-RGLVEDEE--- 63
Q + NI L E+ ++I+ +L + + ++ + +L+ ++ Q + L ++E
Sbjct: 956 QLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKIS 1015
Query: 64 -----WEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITN--- 115
+EK T + + E E + K++ ++ Q+ L +I N
Sbjct: 1016 VLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNK 1075
Query: 116 -----------CEQSSP--DGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCED 162
EQ S + L+E LQ ++ + +EKEL+ + A + ++
Sbjct: 1076 LIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCR 1135
Query: 163 QALYIKKYQETLKKIEEELEALFLEREVSKL 193
Q I K E LK +LE++ +E++ L
Sbjct: 1136 QEKEITKLNEELK--SHKLESI---KEITNL 1161
Score = 32.7 bits (73), Expect = 0.38
Identities = 38/215 (17%), Positives = 91/215 (42%), Gaps = 10/215 (4%)
Query: 3 ISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQR--LESEIIQTRGLVE 60
++ L Q + + + E+D +++E + + + + + + + L+ + +Q+R
Sbjct: 297 VNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSAS 356
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSS 120
+ + + E+ A Q+L+EE + +E K + L +LQQ+ K Q +
Sbjct: 357 ETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEI 416
Query: 121 PDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLK----- 175
+ + + Q EA +E+ L K Q+ D L + + +E LK
Sbjct: 417 NQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVA-DLQLKLSRLEEQLKEKVTN 475
Query: 176 --KIEEELEALFLEREVSKLVSMNPVEKEHTSQNN 208
+++ +L+ + + + + + K +QN+
Sbjct: 476 STELQHQLDKTKQQHQEQQALQQSTTAKLREAQND 510
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 52.0 bits (123), Expect = 6e-07
Identities = 44/195 (22%), Positives = 92/195 (47%), Gaps = 7/195 (3%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
++ L + + + L ++ + + EA+Q+ L +Q EDK+ L ++ V+D
Sbjct: 974 KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDD 1033
Query: 62 EE--WEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKIT--NCE 117
E E+E + M+ ERA ++LE + + L + +L ++L +K ++ N
Sbjct: 1034 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNAR 1093
Query: 118 QSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKI 177
+ + KL++L+A E+EL A V +L D + ++ +E +++
Sbjct: 1094 IEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLS---RELEEISERL 1150
Query: 178 EEELEALFLEREVSK 192
EE A ++ E++K
Sbjct: 1151 EEAGGATSVQIEMNK 1165
Score = 42.7 bits (99), Expect = 4e-04
Identities = 56/223 (25%), Positives = 102/223 (45%), Gaps = 23/223 (10%)
Query: 7 AQSKRNIISLNMDLERDTQ-RIDEA---NQKLLLKIQEREDKIQRLESEIIQTRGLVEDE 62
A++++ + SL L +DTQ ++D+A N L I E + L++E+ + R +VE
Sbjct: 1637 AEAQKQVKSLQ-SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQT 1695
Query: 63 EWEKE--NRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSS 120
E ++ + +E +Q L + L + K + +++LQ ++ Q+ N E+ +
Sbjct: 1696 ERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKA 1755
Query: 121 ----PDGAL--EETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQAL-----YIKK 169
D A+ EE K K Q A +K + + +K+ E AL ++K
Sbjct: 1756 KKAITDAAMMAEELK-KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQK 1814
Query: 170 YQETLKKIEEELEALFLEREVSKLVSMNPVE---KEHTSQNNE 209
+ ++++E ELEA +R + M E KE T Q E
Sbjct: 1815 LEARVRELENELEA-EQKRNAESVKGMRKSERRIKELTYQTEE 1856
Score = 38.9 bits (89), Expect = 0.005
Identities = 53/237 (22%), Positives = 104/237 (43%), Gaps = 31/237 (13%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
EIS L + + +LE+ ++++ +L ++E E ++ E +I++ +
Sbjct: 1508 EISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQ----- 1562
Query: 62 EEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSP 121
+ N+ E ER L E +EE + +R + +V S+ TR + ++
Sbjct: 1563 ---LEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKM- 1618
Query: 122 DGALEETKVKL---QQLEASYACQEKELLKVMKEYAFVTQLCEDQAL-----------YI 167
+G L E +++L ++ A Q K L ++K+ TQ+ D A+ +
Sbjct: 1619 EGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKD----TQIQLDDAVRANDDLKENIAIV 1674
Query: 168 KKYQETLKKIEEELEALFLEREVS-KLVSMNPVEKEHTSQNNEGTPTQKTARLFSKK 223
++ L+ EEL A+ + E S KL +E TS+ + +Q T+ + KK
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIE---TSERVQLLHSQNTSLINQKK 1728
Score = 38.5 bits (88), Expect = 0.007
Identities = 43/211 (20%), Positives = 96/211 (45%), Gaps = 19/211 (9%)
Query: 6 LAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWE 65
+A K L LE+ R E +K++ +QE+ D ++++E Q +E +
Sbjct: 849 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAE--QDNLADAEERCD 906
Query: 66 KENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITN-CEQSSPDGA 124
+ + ++ E ++E+ E RLE + E+ +LT K +K+ + C + D
Sbjct: 907 QLIKNKIQLEAKVKEMNE---RLEDEE--------EMNAELTAKKRKLEDECSELKRD-- 953
Query: 125 LEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEAL 184
+++ ++ L ++E E ++ + +E A + ++ K QE ++ ++L+A
Sbjct: 954 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA- 1012
Query: 185 FLEREVSKLVSMNPVEKEHTSQNNEGTPTQK 215
E + ++ V+ E + EG+ Q+
Sbjct: 1013 --EEDKVNTLTKAKVKLEQQVDDLEGSLEQE 1041
Score = 35.8 bits (81), Expect = 0.045
Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 17/172 (9%)
Query: 25 QRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEE 84
Q + N L+ + ++ + + +L++E+ + + E EK + + +EL++E
Sbjct: 1714 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE-EKAKKAITDAAMMAEELKKE 1772
Query: 85 ---TARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYAC 141
+A LER K + +I +LQ +L Q AL+ K +LQ+LEA
Sbjct: 1773 QDTSAHLERMKKNMEQTIKDLQHRLDEAEQI-----------ALKGGKKQLQKLEARVRE 1821
Query: 142 QEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKL 193
E EL K A + IK+ T + E+ L L+ V KL
Sbjct: 1822 LENELEAEQKRNAESVKGMRKSERRIKEL--TYQTEEDRKNLLRLQDLVDKL 1871
Score = 35.4 bits (80), Expect = 0.058
Identities = 38/185 (20%), Positives = 86/185 (46%), Gaps = 24/185 (12%)
Query: 19 DLERDTQRIDEANQKLLLKIQEREDKIQRLE---SEIIQTRGLVEDEEWEKENRTTMERE 75
D + T+ ++EA +KL ++QE E+ ++ + S + +T+ +++E ++ +ER
Sbjct: 1378 DAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE--IEDLMVDVERS 1435
Query: 76 RALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVK---- 131
A A L++K + + E +QK ++ + ++ + + E K+K
Sbjct: 1436 NA------AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE 1489
Query: 132 --LQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEE---ELEALFL 186
L+ LE ++E + +E + +T+ I + ++ K++E EL++
Sbjct: 1490 ESLEHLETF----KRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1545
Query: 187 EREVS 191
E E S
Sbjct: 1546 EAEAS 1550
Score = 35.0 bits (79), Expect = 0.076
Identities = 31/157 (19%), Positives = 67/157 (42%), Gaps = 12/157 (7%)
Query: 40 EREDKIQRLESEIIQTRGLVE----------DEEWEKENRTTMERERALQELEEETARLE 89
E + + + SE+ Q R E +E +K + E E A++ + + + LE
Sbjct: 1356 ELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLE 1415
Query: 90 RKNKTLVHSITELQQKLTRKSQKIT--NCEQSSPDGALEETKVKLQQLEASYACQEKELL 147
+ L + I +L + R + + +Q + D L E K K ++ ++ +KE
Sbjct: 1416 KTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1475
Query: 148 KVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEAL 184
+ E + E+ +++ ++ K ++EE+ L
Sbjct: 1476 SLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
Score = 31.2 bits (69), Expect = 1.1
Identities = 32/163 (19%), Positives = 74/163 (45%), Gaps = 11/163 (6%)
Query: 33 KLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEK----ENRTTMERER-----ALQELEE 83
K LLK ERE ++ ++ E + + +E E + E ++ +E+ +Q ++
Sbjct: 837 KPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 84 ETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKV--KLQQLEASYAC 141
A E + L+ + +L+ K+ ++++ + E+ + + ++ K+ + +L+
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 142 QEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEAL 184
E L KV KE ++ + E + K+ +E +AL
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKAL 999
Score = 30.4 bits (67), Expect = 1.9
Identities = 40/193 (20%), Positives = 85/193 (44%), Gaps = 20/193 (10%)
Query: 37 KIQEREDKIQRLESEIIQTRGLVEDEEWEK------ENRTTMERERALQELEEETARLER 90
K+ ER D + ++ I G V++ W K + ERE+ + ++EE RL+
Sbjct: 803 KLLERRDSLLVIQWNIRAFMG-VKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLK- 860
Query: 91 KNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQE--KELLK 148
++ + + + +K+ + Q D L+ + +A C + K ++
Sbjct: 861 ------EALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQ 914
Query: 149 VMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKL-VSMNPVEKE-HTSQ 206
+ + + + ED+ + +K+E+E L+R++ L +++ VEKE H ++
Sbjct: 915 LEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSE--LKRDIDDLELTLAKVEKEKHATE 972
Query: 207 NNEGTPTQKTARL 219
N T++ A L
Sbjct: 973 NKVKNLTEEMAGL 985
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 51.6 bits (122), Expect = 8e-07
Identities = 50/203 (24%), Positives = 98/203 (48%), Gaps = 19/203 (9%)
Query: 4 SRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEII---QTRGLVE 60
++L +++R + D + E + LL + + +++ L+S+++ ++ LVE
Sbjct: 971 TQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVE 1030
Query: 61 DEEWEKENRTTMERERALQELEEETARL-----ERKNKTLV----HSITELQQKLTRKSQ 111
E EK R T E R +ELE E A L E++ + LV SI + + R+
Sbjct: 1031 QEVQEKL-RETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDM 1089
Query: 112 KITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIK--- 168
+ EQ +E + ++++ EA + QE +LL+ + E + +T+ +L+ +
Sbjct: 1090 QEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEEL-EASHITEQQLRASLWAQEAK 1148
Query: 169 --KYQETLKKIEEELEALFLERE 189
+ Q L+ E +LEAL E++
Sbjct: 1149 AAQLQLRLRSTESQLEALAAEQQ 1171
Score = 38.9 bits (89), Expect = 0.005
Identities = 43/211 (20%), Positives = 95/211 (45%), Gaps = 42/211 (19%)
Query: 21 ERDTQRI---------DEANQKLLLKIQERED----------KIQRLESEIIQTRGLVED 61
+R+TQR+ +E +Q+L + + D ++Q + E+ R +E+
Sbjct: 1582 QRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEE 1641
Query: 62 EEWEKENRTTMERERALQELEEETARLE-------RKNKTLVHSITELQQKLTRKSQKIT 114
+ +KE+ T + ER QEL + R++ R+ K L + +++ L + +++T
Sbjct: 1642 LQRQKEH-LTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELT 1700
Query: 115 NCEQ-------------SSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCE 161
Q + G+LE K+ L+ E CQ++ + ++ + + Q +
Sbjct: 1701 TQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQ--Q 1758
Query: 162 DQALYIKKYQETLKKIEEELEALFLEREVSK 192
Q L+ K + +L + E E + L++++ +
Sbjct: 1759 LQGLHRKVGETSLLLSQREQEIVVLQQQLQE 1789
Score = 38.5 bits (88), Expect = 0.007
Identities = 42/203 (20%), Positives = 91/203 (44%), Gaps = 38/203 (18%)
Query: 6 LAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQE-------REDKIQRLESEIIQTRGL 58
L+Q ++ I+ L L+ ++ + Q L ++ E R+ +++ L+ E Q +G
Sbjct: 1773 LSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQ 1832
Query: 59 VEDEE---------WEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRK 109
E + E+ + T ER LQ+ +E+ RLE ++L +
Sbjct: 1833 EERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLE--------------EELAVE 1878
Query: 110 SQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKK 169
+++ E+ L + + + ++ E + +++ + +E+ T+ +D L +
Sbjct: 1879 GRRVQALEE-----VLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWL---Q 1930
Query: 170 YQETLKKIEEELEALFLEREVSK 192
Q LK+ ++ELEAL E + S+
Sbjct: 1931 AQAVLKERDQELEALRAESQSSR 1953
Score = 37.0 bits (84), Expect = 0.020
Identities = 33/184 (17%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Query: 30 ANQKLLLKIQEREDKIQRLES-----EIIQTRGLVEDEEWEKENRTTMERERALQELEEE 84
A L LK +E E + +R ++ E+ +G E +T ERE ++ L +
Sbjct: 1384 ARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQ 1443
Query: 85 TARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPD-----GALEETKVKLQQLEASY 139
LE++ + ++ L L +++Q++ ++ + LE + +Q+ E
Sbjct: 1444 IQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKL 1503
Query: 140 ACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPV 199
Q +++ ++ K+ + E Q L ++K + ++ +++ L + + +++
Sbjct: 1504 TVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELE 1563
Query: 200 EKEH 203
E H
Sbjct: 1564 ENHH 1567
Score = 35.0 bits (79), Expect = 0.076
Identities = 47/217 (21%), Positives = 93/217 (42%), Gaps = 17/217 (7%)
Query: 4 SRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE--D 61
S + + + SL L+R+ +R+ A ++ + E +K Q L + QT+ V
Sbjct: 2132 SPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQ 2191
Query: 62 EEWEKENRTTMERERALQELEEE---TARLERKNKTLVHSITELQQKLTRKSQKITNCEQ 118
E + +ER+ Q L++E T R K + T + +R Q + E
Sbjct: 2192 EVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEV 2251
Query: 119 S------SPDGALEET-KVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQ 171
S SPDG +++ + +L+ L+ + A E + ++ + + E +++ +
Sbjct: 2252 SGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQ----VERER 2307
Query: 172 ETLKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNN 208
LK+ E A E+SK + +P +++ Q N
Sbjct: 2308 RKLKR-EAMRAAQAGSLEISKATASSPTQQDGRGQKN 2343
Score = 29.3 bits (64), Expect = 4.2
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 12/100 (12%)
Query: 64 WEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCE--QSSP 121
W+ + + R++ +Q+LEE E + + + +LQ++L++ ++ + E Q+S
Sbjct: 1253 WKTQQTRDVLRDQ-VQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSL 1311
Query: 122 DG---ALEETKVKLQ------QLEASYACQEKELLKVMKE 152
+ L ET LQ +L+ A E+ELL+ KE
Sbjct: 1312 ESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKE 1351
Score = 28.5 bits (62), Expect = 7.2
Identities = 50/223 (22%), Positives = 88/223 (39%), Gaps = 45/223 (20%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKL---LLKIQEREDKIQRLESEI----- 52
++++ + + + N LE Q+ +EA +L L IQE +++IQ+ SE
Sbjct: 645 VDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQE 704
Query: 53 ------------------IQTRGLVEDEEWEKENRTTMER----ERALQELEEETARLER 90
+ R + E E +E R ER Q+L E+ L
Sbjct: 705 AATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSS 764
Query: 91 KNKTLVHSITELQQ----------KLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYA 140
+ L S+ E QQ +L + Q +T ++ G + K++L E S A
Sbjct: 765 AKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVI-QGEVRCLKLEL-DTERSQA 822
Query: 141 CQEKELLK---VMKEYAFVTQLCEDQALYIKKYQETLKKIEEE 180
QE++ E T L + +A + K+ + +K E+E
Sbjct: 823 EQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKE 865
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/196 (24%), Positives = 93/196 (47%), Gaps = 9/196 (4%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
++ L + + + L ++ + + EA+Q+ L +Q EDK+ L ++ V+D
Sbjct: 976 KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDD 1035
Query: 62 EE--WEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS 119
E E+E + M+ ERA ++LE + + L + +L++KL +K I
Sbjct: 1036 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSK 1095
Query: 120 SPDG---ALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKK 176
D AL+ K KL++ +A E+EL A V +L D + ++ +E ++
Sbjct: 1096 IEDEQVLALQLQK-KLKENQARIEELEEELEAERTARAKVEKLRSDLS---RELEEISER 1151
Query: 177 IEEELEALFLEREVSK 192
+EE A ++ E++K
Sbjct: 1152 LEEAGGATSVQIEMNK 1167
Score = 44.7 bits (104), Expect = 1e-04
Identities = 57/223 (25%), Positives = 102/223 (45%), Gaps = 23/223 (10%)
Query: 7 AQSKRNIISLNMDLERDTQ-RIDEA---NQKLLLKIQEREDKIQRLESEIIQTRGLVEDE 62
A++++ + SL L +DTQ ++D+A N L I E + L++E+ + R +VE
Sbjct: 1639 AEAQKQVKSLQ-SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQT 1697
Query: 63 EWEKE--NRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSS 120
E ++ + +E +Q L + L + K + +T+LQ ++ Q+ N E+ +
Sbjct: 1698 ERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKA 1757
Query: 121 ----PDGAL--EETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQAL-----YIKK 169
D A+ EE K K Q A +K + + +K+ E AL ++K
Sbjct: 1758 KKAITDAAMMAEELK-KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQK 1816
Query: 170 YQETLKKIEEELEALFLEREVSKLVSMNPVE---KEHTSQNNE 209
+ ++++E ELEA +R + M E KE T Q E
Sbjct: 1817 LEARVRELEGELEA-EQKRNAESVKGMRKSERRIKELTYQTEE 1858
Score = 38.1 bits (87), Expect = 0.009
Identities = 45/172 (26%), Positives = 75/172 (43%), Gaps = 17/172 (9%)
Query: 25 QRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEE 84
Q + N L+ + ++ E + +L+SE+ + + E EK + + +EL++E
Sbjct: 1716 QLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAE-EKAKKAITDAAMMAEELKKE 1774
Query: 85 ---TARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYAC 141
+A LER K + +I +LQ +L Q AL+ K +LQ+LEA
Sbjct: 1775 QDTSAHLERMKKNMEQTIKDLQHRLDEAEQI-----------ALKGGKKQLQKLEARVRE 1823
Query: 142 QEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKL 193
E EL K A + IK+ T + E++ L L+ V KL
Sbjct: 1824 LEGELEAEQKRNAESVKGMRKSERRIKEL--TYQTEEDKKNLLRLQDLVDKL 1873
Score = 37.0 bits (84), Expect = 0.020
Identities = 43/211 (20%), Positives = 96/211 (45%), Gaps = 19/211 (9%)
Query: 6 LAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWE 65
+A K + LE+ R E +K++ +QE+ D ++++E Q +E +
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAE--QDNLNDAEERCD 908
Query: 66 KENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITN-CEQSSPDGA 124
+ + ++ E ++E+ E RLE + E+ +LT K +K+ + C + D
Sbjct: 909 QLIKNKIQLEAKVKEMNE---RLEDEE--------EMNAELTAKKRKLEDECSELKKD-- 955
Query: 125 LEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEAL 184
+++ ++ L ++E E ++ + +E A + ++ K QE ++ L+ L
Sbjct: 956 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA---HQQALDDL 1012
Query: 185 FLEREVSKLVSMNPVEKEHTSQNNEGTPTQK 215
+E + +S + V+ E + EG+ Q+
Sbjct: 1013 QVEEDKVNSLSKSKVKLEQQVDDLEGSLEQE 1043
Score = 36.6 bits (83), Expect = 0.026
Identities = 46/215 (21%), Positives = 89/215 (41%), Gaps = 33/215 (15%)
Query: 3 ISRLAQSKRNIISLNMDLERDTQRIDEANQKL------------LLKIQERED-----KI 45
IS+L + K + DL+R + +A L LL+ Q E+ ++
Sbjct: 1300 ISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 1359
Query: 46 QRL----ESEIIQTRGLVED------EEWEKENRTTMER----ERALQELEEETARLERK 91
QR+ SE+ Q R E EE E+ + +R E A++ + + + LE+
Sbjct: 1360 QRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKT 1419
Query: 92 NKTLVHSITELQQKLTRKSQKITNCE--QSSPDGALEETKVKLQQLEASYACQEKELLKV 149
L + I +L + R + + Q + D L E K K ++ ++ +KE +
Sbjct: 1420 KHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSL 1479
Query: 150 MKEYAFVTQLCEDQALYIKKYQETLKKIEEELEAL 184
E + E+ +++ ++ K ++EE+ L
Sbjct: 1480 STELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1514
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 51.2 bits (121), Expect = 1e-06
Identities = 53/221 (23%), Positives = 96/221 (43%), Gaps = 30/221 (13%)
Query: 20 LERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQ 79
LER+ QR+ E N +L K+ E +++E+ +++GL + ENRT + LQ
Sbjct: 633 LERELQRLQEENGRLARKVTSLETATEKVEALEHESQGL------QLENRTLRKSLDTLQ 686
Query: 80 ELEEETARLERKNKTLVHSITELQ---QKLTRKSQKITNCEQSSPDGALEETKV------ 130
+ + LER NK L EL+ + + S K+ E+ + E+ ++
Sbjct: 687 NVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLEREKEELRKNVDL 746
Query: 131 ------KLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEAL 184
K ++LE SY E L++ Q E + + + L ++E E +AL
Sbjct: 747 LKALGKKSERLELSYQSVSAENLRLQ-------QSLESSSHKTQTLESELGELEAERQAL 799
Query: 185 FLEREVSKLVS--MNPVEKEHTSQNNEGTPTQKTARLFSKK 223
+ E +L + + EK+ + E +K +L K+
Sbjct: 800 RRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKE 840
Score = 42.4 bits (98), Expect = 5e-04
Identities = 51/200 (25%), Positives = 79/200 (39%), Gaps = 41/200 (20%)
Query: 20 LERDTQRIDEANQKLLLKIQEREDKIQRLESEI----IQTRGLVEDEEWEKENRTTME-R 74
LE Q + N +L ++ K Q LESE+ + + L D E + +E
Sbjct: 757 LELSYQSVSAENLRLQQSLESSSHKTQTLESELGELEAERQALRRDLEALRLANAQLEGA 816
Query: 75 ERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQ 134
E+ + LE+E A+LE+ K L L Q++ K D L+++ KL
Sbjct: 817 EKDRKALEQEVAQLEKDKKLLEKEAKRLWQQVELK------------DAVLDDSTAKLSA 864
Query: 135 LEASYACQEKELLK---------------------VMKEYAFVTQLCEDQALYIKKYQE- 172
+E +KEL + V +T L ED L K Q+
Sbjct: 865 VEKESRALDKELARCRDAAGKLKELEKDNRDLTKQVTVHARTLTTLREDLVLEKLKSQQL 924
Query: 173 --TLKKIEEELEALFLEREV 190
L K+ +ELE + L RE+
Sbjct: 925 SSELDKLSQELEKVGLNREL 944
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/182 (25%), Positives = 83/182 (45%), Gaps = 8/182 (4%)
Query: 15 SLNMDLERDTQRID-EANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTME 73
S + LE T R + Q + L+++ E ++L++E ++ R LVE + ME
Sbjct: 668 SQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQME 727
Query: 74 RERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQ 133
RE E E+E RKN L+ ++ + ++L Q + + E +LE + K Q
Sbjct: 728 RENQQLEREKEEL---RKNVDLLKALGKKSERLELSYQSV-SAENLRLQQSLESSSHKTQ 783
Query: 134 QLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELE--ALFLEREVS 191
LE+ E E + ++ +L Q +K ++ L++ +LE LE+E
Sbjct: 784 TLESELGELEAERQALRRDLE-ALRLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKEAK 842
Query: 192 KL 193
+L
Sbjct: 843 RL 844
Score = 40.8 bits (94), Expect = 0.001
Identities = 53/204 (25%), Positives = 91/204 (44%), Gaps = 16/204 (7%)
Query: 8 QSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKE 67
Q + I L LER+ Q + I+E+E +E+ ++D E EK+
Sbjct: 505 QLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKD 564
Query: 68 --NRTTME-RERALQELEEETARLERKNKTLVHSITELQQKLTR----KSQKITNCEQSS 120
NR RER+ E +E++NK L ++TE KL++ K Q + EQ+
Sbjct: 565 HLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAK 624
Query: 121 PDG-ALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQL-CEDQALY-----IKKYQET 173
G E+ + +LQ+L+ +++ + V L E Q L ++K +T
Sbjct: 625 EKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEALEHESQGLQLENRTLRKSLDT 684
Query: 174 LKKIEEELEALFLEREVSKLVSMN 197
L+ + +LE LER+ +L + N
Sbjct: 685 LQNVSLQLEG--LERDNKQLDAEN 706
Score = 35.0 bits (79), Expect = 0.076
Identities = 55/242 (22%), Positives = 100/242 (41%), Gaps = 54/242 (22%)
Query: 8 QSKRNIISLNMDLERDTQRIDEA-NQKLLLKIQEREDKIQRL----ESEIIQTRGLVEDE 62
Q K + L +D + D +RI+E + ++L+I +++ + E E + + D
Sbjct: 389 QLKSKLHDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWELEQLSKNADLSDA 448
Query: 63 ------------------EWEKENRTTMERERALQE----LEE---ETARLERKNKTLVH 97
+ EKEN++ + L++ LEE + LE++N L
Sbjct: 449 SRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLVLEESGLKCGELEKENHQLSK 508
Query: 98 SITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVT 157
I +LQ +L R+ Q + E S EE + +QL++ + E LK
Sbjct: 509 KIEKLQTQLEREKQSNQDLETLS-----EELIREKEQLQS-----DMETLKA-------- 550
Query: 158 QLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTA 217
D+A IK ++ + + +L +VS M VEKE+ + + T T+
Sbjct: 551 ----DKARQIKDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQ--TVTEANG 604
Query: 218 RL 219
+L
Sbjct: 605 KL 606
Score = 28.5 bits (62), Expect = 7.2
Identities = 32/148 (21%), Positives = 63/148 (42%), Gaps = 13/148 (8%)
Query: 17 NMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWE------KENRT 70
N L + R++ + +L + +E + L++ + + +E W+ KE
Sbjct: 1251 NQRLRGELDRVNFLHHQLKGEYEELHAHTKELKTSLNNAQ--LELNRWQARFDELKEQHQ 1308
Query: 71 TMERERALQELEEETARLERKNKTLV---HSITELQQKLTRKSQKITNCEQSSPDGALEE 127
TM+ +L +L+ L R L H + Q L++++Q + + + EE
Sbjct: 1309 TMDI--SLTKLDNHCELLSRLKGNLEEENHHLLSQIQLLSQQNQMLLEQNMENKEQYHEE 1366
Query: 128 TKVKLQQLEASYACQEKELLKVMKEYAF 155
K + +L A +EK K+M +Y F
Sbjct: 1367 QKQYIDKLNALRRHKEKLEEKIMDQYKF 1394
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 50.4 bits (119), Expect = 2e-06
Identities = 37/163 (22%), Positives = 83/163 (50%), Gaps = 9/163 (5%)
Query: 25 QRIDEANQKLLL---KIQEREDKIQRLESEIIQTRGLV-EDEEWEKENRTTMERERALQE 80
++I E +K+ KI+E+E+KI+ E +I + ++ E EE E M+ + ++
Sbjct: 509 EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRR 568
Query: 81 LEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYA 140
EE+ E K + I E ++K+ + +KI E+ ++E + K+ + E
Sbjct: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE-----MMQEQEEKMWEQEEKMC 623
Query: 141 CQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEA 183
QE+++ + ++ + +Q + +++ +E +++ +E LEA
Sbjct: 624 EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 49.7 bits (117), Expect = 3e-06
Identities = 40/134 (29%), Positives = 65/134 (48%), Gaps = 5/134 (3%)
Query: 16 LNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEE---WEKENRTTM 72
LN E R +E Q+ KIQE+E+KI+ E +I + + +E WEKE +
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK-MR 352
Query: 73 ERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKL 132
+E + E EE+ RLE I EL++K+ + +KI E+ + + K
Sbjct: 353 RQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM-HEQEKIREQEEKRQEEEKIREQEKR 411
Query: 133 QQLEASYACQEKEL 146
Q+ EA QE+++
Sbjct: 412 QEQEAKMWRQEEKI 425
Score = 48.1 bits (113), Expect = 9e-06
Identities = 52/213 (24%), Positives = 100/213 (46%), Gaps = 17/213 (7%)
Query: 28 DEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETAR 87
+E ++L + E+E+KI+ LE ++ + + E EE +E E+E+ QE E + R
Sbjct: 362 EEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR-QEQEAKMWR 420
Query: 88 LERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEE------TKVKLQQLEASYAC 141
E K + I E ++K+ R+ +KI E+ + +E + K+++ E +
Sbjct: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 480
Query: 142 QEK--ELLKVMKEYAFV---TQLCEDQALYIKKYQETL----KKIEEELEAL-FLEREVS 191
+EK E K+ K+ V + DQ I++ +E + +KI E+ E + E ++
Sbjct: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 192 KLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKI 224
+ M ++E + E Q+ R +KI
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Score = 39.7 bits (91), Expect = 0.003
Identities = 38/179 (21%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 39 QEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHS 98
Q++E+K+ R E +I +EWE++ E+E ++E EE+ E K +
Sbjct: 296 QQQEEKMWRQEEKI---------QEWEEK---IQEQEEKIREQEEKIREQEEKMRRQEEM 343
Query: 99 ITELQQKLTRKSQKITNCEQSSP--DGALEETKVKLQQLEASYACQEK----ELLKVMKE 152
+ E ++K+ R+ + + E+ + + E + K+++LE QEK E + +E
Sbjct: 344 MWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 403
Query: 153 YAFVTQLCEDQALYIKKYQETLKKIEEEL--EALFLEREVSKLVSMNPVEKEHTSQNNE 209
+ ++Q + + +E +++ EE++ + + R+ K+ + +E Q E
Sbjct: 404 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 462
Score = 39.3 bits (90), Expect = 0.004
Identities = 42/207 (20%), Positives = 89/207 (42%), Gaps = 9/207 (4%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQE 80
E++ R +E Q+ ++ +E+KI+ E Q + E E+ K+ +E + +
Sbjct: 448 EQEKIREEEKRQEQE-EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506
Query: 81 LEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYA 140
EE+ E K I E ++K+ + +KI E+ ++E + K+ + E
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE-----MMQEQEEKMGEQEEKMQ 561
Query: 141 CQEK---ELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMN 197
QEK + K+ ++ + + E +K E +KI E+ E + + E
Sbjct: 562 EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
Query: 198 PVEKEHTSQNNEGTPTQKTARLFSKKI 224
E+E Q E ++ +++ +++
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKMWEQEV 648
Score = 36.6 bits (83), Expect = 0.026
Identities = 42/193 (21%), Positives = 84/193 (43%), Gaps = 38/193 (19%)
Query: 22 RDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEE-------WEKENRTT--- 71
R ++I E +K I+E+E K+ R E +I + + E+E+ W +E +
Sbjct: 420 RQEEKIREQEEK----IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475
Query: 72 --------MERERALQELEEETARLERKNKTLVHSITELQQKLTR-------KSQKITNC 116
M + +++ EE+ R E K I E ++K+ R + +KI
Sbjct: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
Query: 117 EQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKK 176
E+ + E + +Q+ E QE+++ + K ++ E + +K +E +K
Sbjct: 536 EEK-----IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQE----EKIREQKEK 586
Query: 177 IEEELEALFLERE 189
I E+ E ++ + E
Sbjct: 587 IREQEEKIWEQEE 599
Score = 35.4 bits (80), Expect = 0.058
Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 16/94 (17%)
Query: 20 LERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQ 79
+ R ++I E +K I+E+++KI+ E +I WE+E + E+E +Q
Sbjct: 566 MRRQEEKIREQEEK----IREQKEKIREQEEKI-----------WEQEEK-IREQEEMMQ 609
Query: 80 ELEEETARLERKNKTLVHSITELQQKLTRKSQKI 113
E EE+ E K + E ++K+ R+ +K+
Sbjct: 610 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643
Score = 31.6 bits (70), Expect = 0.84
Identities = 46/225 (20%), Positives = 94/225 (41%), Gaps = 20/225 (8%)
Query: 3 ISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDE 62
+ +L R++IS D + +++A L + ++ K R E+ + R + E
Sbjct: 153 VKQLEGEARDLISRLHDSWKFAGELEQA----LSAVATQKKKADRYIEELTKERDALSLE 208
Query: 63 EWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPD 122
+ R T+ E EL+E+ A+L+ K + + +E+Q + +K+ + P
Sbjct: 209 LY----RNTITDE----ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ 260
Query: 123 GAL----EETKVKLQQLEASYACQ--EKELLKVMKEYAFVTQLCEDQAL--YIKKYQETL 174
L + +LQ + A Q E EL + + +++ + + +K QE
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Query: 175 KKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARL 219
+KI E+ E + + E + EKE + E +K ++
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 50.4 bits (119), Expect = 2e-06
Identities = 51/221 (23%), Positives = 98/221 (44%), Gaps = 15/221 (6%)
Query: 6 LAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEII-QTRGLVEDEEW 64
L + ++ I + R +R+ E K+ +E+E+K+ R E + Q + L E E+
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKM----REQEEKMWRQEKRLREQEKELREQEKE 336
Query: 65 EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS----- 119
+E + E+E +QE EE+ E K + + +++L + +++ EQ
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Query: 120 ----SPDGALEETKVKLQQLEASYACQEK-ELLKVMKEYAFVTQLCEDQALYIKKYQETL 174
D L E + ++++ E + EK K M+E T+ E++ ++ +E
Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 175 KKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQK 215
KK+ EE E + + E + N E+E + P QK
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 497
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/165 (21%), Positives = 84/165 (50%), Gaps = 13/165 (7%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEE---WEKENRTTMERERA 77
E+ + +E ++ K+QE+E+K+Q E ++ + ++++E WE+E + + E+
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEK- 653
Query: 78 LQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKV-KLQQLE 136
+ E+ E+K K H + Q+K+ + +KI E+ +E K +++
Sbjct: 654 ---MWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710
Query: 137 ASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEEL 181
+ +E+E K M+E ++ +Q +++ +E +++ EEE+
Sbjct: 711 EEESMRERE--KKMRE---EEEMMREQEEKMQEQEEKMQEQEEEM 750
Score = 41.6 bits (96), Expect = 8e-04
Identities = 41/242 (16%), Positives = 101/242 (41%), Gaps = 23/242 (9%)
Query: 1 MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVE 60
+E+ R + + N +L+ + ++ L ++E + K++R + + Q +
Sbjct: 211 LELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTL 270
Query: 61 DEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSS 120
EE ++ E+E+ +++ EE+ R E + + + E ++K+ R+ +++ E+
Sbjct: 271 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKEL 330
Query: 121 PDGALE----------------------ETKVKLQQLEASYACQEKELLKVMKEYAFVTQ 158
+ E E + K+++ E QE+ L + K+ Q
Sbjct: 331 REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 390
Query: 159 LCEDQALYIKKYQETLKKIEEEL-EALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTA 217
DQ + + E L++ EE + E + +V K+ ++++ ++ Q+
Sbjct: 391 KMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE 450
Query: 218 RL 219
R+
Sbjct: 451 RI 452
Score = 38.5 bits (88), Expect = 0.007
Identities = 34/171 (19%), Positives = 80/171 (46%), Gaps = 28/171 (16%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEE--WEKENRTTMERERAL 78
E QR+ E +KL ++K+Q E +I + + D+E W +E + M R+ +
Sbjct: 487 EWQQQRLPEQKEKLW-----EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK--MWRQEKM 539
Query: 79 QELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEAS 138
+E E++ E K + + + ++++ +K+Q+ + EE +++ ++ +
Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599
Query: 139 YACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLERE 189
+E+E+++ +E K QE +K++E+ E ++ + E
Sbjct: 600 ---EEEEMMREQEE----------------KMQEQEEKMQEQEEKMWEQEE 631
Score = 37.7 bits (86), Expect = 0.012
Identities = 41/200 (20%), Positives = 83/200 (41%), Gaps = 12/200 (6%)
Query: 25 QRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTM-ERERALQELEE 83
+++ + QK+ + + E K Q E + + +EE +E M E E ++E EE
Sbjct: 551 EKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 610
Query: 84 ETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSS--------PDGALEETKVKLQQL 135
+ E K + + E ++K+ + +K+ E+ L E K KL +
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 670
Query: 136 EASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVS 195
E QE+E ++ +E + + E + +K +K+ EE E+++ +
Sbjct: 671 E---KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 196 MNPVEKEHTSQNNEGTPTQK 215
M ++E + E Q+
Sbjct: 728 MMREQEEKMQEQEEKMQEQE 747
Score = 35.0 bits (79), Expect = 0.076
Identities = 40/177 (22%), Positives = 75/177 (42%), Gaps = 33/177 (18%)
Query: 23 DTQRIDEANQKLLL--------KIQEREDKI----------QRLESEIIQTRGLVEDEEW 64
+ QR+ E +KL K+QE+E+KI Q E + + E+E
Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715
Query: 65 EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGA 124
+ + E E ++E EE+ E K + + E ++K+ + +K+ ++
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR------ 769
Query: 125 LEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEEL 181
L E K KL + E QE+E + +E DQ ++ +E ++ EE++
Sbjct: 770 LPEQKEKLWEHE---KMQEQEKIWEQEE------KMRDQEEKMRGQEEKMRGQEEKM 817
Score = 34.7 bits (78), Expect = 0.100
Identities = 43/214 (20%), Positives = 91/214 (42%), Gaps = 27/214 (12%)
Query: 37 KIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTM-ERERALQELEE----------ET 85
K+QE+E K + E ++ + + E E+ +E TM E+E +Q+ EE +
Sbjct: 431 KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 490
Query: 86 ARLERKNKTL--VHSITELQQKLTRKSQKITNCEQ--------------SSPDGALEETK 129
RL + + L + E ++K+ + +KI + E+ + + E +
Sbjct: 491 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 550
Query: 130 VKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLERE 189
K++ E QE+ + K +E T E++ ++ +E KK+ EE E + + E
Sbjct: 551 EKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 610
Query: 190 VSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKK 223
+ E+E E ++ +++ ++
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Score = 34.3 bits (77), Expect = 0.13
Identities = 36/164 (21%), Positives = 80/164 (48%), Gaps = 12/164 (7%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQE 80
E+ + +E ++ K+QE+E+K+Q E E+ + E++ WE+E + M ++ L E
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQ----EEKMWEQEEK--MWEQQRLPE 772
Query: 81 LEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYA 140
+E+ E+ + I E ++K+ + +K+ E+ +E K++ Q+ E +
Sbjct: 773 QKEKLWEHEKMQEQ--EKIWEQEEKMRDQEEKMRGQEEKMRG---QEEKMRGQE-EKMWG 826
Query: 141 CQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEAL 184
+EK + K + ++ + +K Q +K+ E+ E +
Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKM 870
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 50.4 bits (119), Expect = 2e-06
Identities = 46/215 (21%), Positives = 95/215 (44%), Gaps = 25/215 (11%)
Query: 2 EISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVED 61
++ L + + L ++ + + EA+Q+ L +Q EDK+ L + V+D
Sbjct: 978 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDD 1037
Query: 62 EEW--EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS 119
E E+E + M+ ERA ++LE + + + +L +KL +K +++N +
Sbjct: 1038 LEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGK 1097
Query: 120 SPD---------GALEETKVKLQQLE-------ASYACQEKELLKVMKEYAFVTQLCED- 162
D ++E + ++++LE AS A EK+ + +E +++ E+
Sbjct: 1098 IEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1157
Query: 163 ------QALYIKKYQETLKKIEEELEALFLEREVS 191
Q KK + +K+ +LE L+ E +
Sbjct: 1158 GGATSAQIEMNKKREAEFQKMRRDLEESTLQHEAT 1192
Score = 37.4 bits (85), Expect = 0.015
Identities = 41/195 (21%), Positives = 88/195 (45%), Gaps = 32/195 (16%)
Query: 16 LNMDLERDTQRIDEANQKLLLKIQEREDKI-----------QRLESEIIQTRGLVED--- 61
L LER T+R + ++ LL ER + ++LE++I Q +G +ED
Sbjct: 1692 LRASLER-TERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQ 1750
Query: 62 ---EEWEKENRTTMERERALQELEEE---TARLERKNKTLVHSITELQQKLTRKSQKITN 115
EK + + +EL++E +A LER K + ++ +LQ +L Q
Sbjct: 1751 EARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALK 1810
Query: 116 CEQSSPDGALEETKVKLQQLEASYACQEKELLKVMK-------EYAFVTQLCEDQALYIK 168
+ +++ + ++++LE+ ++K ++ +K +T E+ I
Sbjct: 1811 GGKKQ----IQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNIL 1866
Query: 169 KYQETLKKIEEELEA 183
+ Q+ + K++ +++A
Sbjct: 1867 RLQDLVDKLQTKVKA 1881
Score = 35.8 bits (81), Expect = 0.045
Identities = 46/240 (19%), Positives = 106/240 (44%), Gaps = 39/240 (16%)
Query: 5 RLAQSKRNIISLNM---DLERDTQRIDEANQKLLLKIQERE------DKIQRLESEII-- 53
RL ++ ++ ++N LE+ QR+ + L++ ++ DK QR +++
Sbjct: 1400 RLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAE 1459
Query: 54 ------QTRGLVEDEEWEKENRTT--MERERALQELEEETARLERKNKTLVHSITELQQK 105
+T+ +E + E + +T + + A +E + L+R+NK L I++L ++
Sbjct: 1460 WKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQ 1519
Query: 106 LTR------------------KSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELL 147
+ KS+ T+ E++ EE K+ QLE + E +
Sbjct: 1520 IAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEID-R 1578
Query: 148 KVMKEYAFVTQLCEDQALYIKKYQETL-KKIEEELEALFLEREVSKLVSMNPVEKEHTSQ 206
K+ ++ + QL + ++ Q TL +I +AL +++++ ++ ++ H ++
Sbjct: 1579 KIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANR 1638
Score = 35.4 bits (80), Expect = 0.058
Identities = 45/168 (26%), Positives = 80/168 (47%), Gaps = 27/168 (16%)
Query: 58 LVEDEEWEKENRTTMER-ERALQELEEETAR---LERKNKTLVHSITELQQKLTRKSQKI 113
L++ E EKE E E+ +EL + A+ LE K TL+ +LQ ++ ++ +
Sbjct: 843 LLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADAL 902
Query: 114 TNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQET 173
+ E+ L +TK+ QLEA +KE VT+ ED+ +
Sbjct: 903 ADAEERCDQ--LIKTKI---QLEAK-----------IKE---VTERAEDEEEINAELTAK 943
Query: 174 LKKIEEELEALFLEREVSKL-VSMNPVEKE-HTSQNNEGTPTQKTARL 219
+K+E+E L++++ L +++ VEKE H ++N T++ A L
Sbjct: 944 KRKLEDECSE--LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 989
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 50.1 bits (118), Expect = 2e-06
Identities = 35/149 (23%), Positives = 79/149 (53%), Gaps = 14/149 (9%)
Query: 37 KIQEREDKIQRLESEIIQTRGLVEDEEWE--KENRTTMERERALQELEEETARLERKNKT 94
KI+E+E+KI+ E +I + + +++E + ++ E+E +QE EE+ R E K
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK--- 642
Query: 95 LVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYA 154
I E ++K+ + +KI E+ ++E + K+ + E QE+++ + ++
Sbjct: 643 ----IREQEKKIREQEEKIREQEE-----MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 693
Query: 155 FVTQLCEDQALYIKKYQETLKKIEEELEA 183
+ +Q + +++ +E +++ +E LEA
Sbjct: 694 RQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 48.1 bits (113), Expect = 9e-06
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 31/197 (15%)
Query: 16 LNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEE---WEKENRTTM 72
LN E R +E Q+ KIQE+E+KI+ E +I + + +E WEKE +
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK-MR 413
Query: 73 ERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKL 132
+E + E EE+ R E I EL++K+ + +KI E+ EE K++
Sbjct: 414 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM-HEQEKIREQEEKRQ----EEEKIRE 468
Query: 133 QQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSK 192
Q+ QE+E +E +K +E +KI E+ E ++ R+ K
Sbjct: 469 QEKR-----QEQEAKMWRQE---------------EKIREQEEKIREQEEKMW--RQEEK 506
Query: 193 LVSMNPVEKEHTSQNNE 209
+ + +E Q E
Sbjct: 507 IHEQEKIREEEKRQEQE 523
Score = 43.5 bits (101), Expect = 2e-04
Identities = 42/192 (21%), Positives = 90/192 (46%), Gaps = 32/192 (16%)
Query: 22 RDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEE-------WEKENRTTM-- 72
R ++I E +K I+E+E+K+ R E +I + + E+E+ W +E +
Sbjct: 481 RQEEKIREQEEK----IREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 536
Query: 73 ----------ERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPD 122
E+E +++ EE+ R E K I E ++K+ R+ +KI E+
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK--- 593
Query: 123 GALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETL----KKIE 178
+ E + K+++ E QE+++ + ++ + ++Q +++ +E + KKI
Sbjct: 594 --IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651
Query: 179 EELEALFLEREV 190
E+ E + + E+
Sbjct: 652 EQEEKIREQEEM 663
Score = 39.3 bits (90), Expect = 0.004
Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 4/74 (5%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEE---WEKENRTTMERERA 77
E Q +E ++ KI+E+E KI+ E +I + +++++E WE+E + E+E
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK-MCEQEEK 684
Query: 78 LQELEEETARLERK 91
+QE EE+ R E K
Sbjct: 685 MQEQEEKMRRQEEK 698
Score = 35.0 bits (79), Expect = 0.076
Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 10/116 (8%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQE 80
E TQ +E + K+ E+E+K+Q E ++ + ++E+ ++ + E+E ++E
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRR-----QEEKIREQEKKIREQEEKIRE 659
Query: 81 LEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLE 136
EE E K + E ++K+ + +K+ E+ + E +V+L+Q E
Sbjct: 660 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK-----MWEQEVRLRQQE 710
Score = 34.3 bits (77), Expect = 0.13
Identities = 40/199 (20%), Positives = 87/199 (43%), Gaps = 30/199 (15%)
Query: 25 QRIDEANQKL--LLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTM--------ER 74
++I E +K+ KI+E+E+K Q E + ++E +E M E+
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEK--------IREQEKRQEQEAKMWRQEEKIREQ 489
Query: 75 ERALQELEEETARLERK----NKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKV 130
E ++E EE+ R E K K + Q+++ R+ +KI E+ + K
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE------IWRQKE 543
Query: 131 KLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREV 190
K+ + E QE+++ + ++ + +Q + + +E +++ EE++ E ++
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE--QEEKI 601
Query: 191 SKLVSMNPVEKEHTSQNNE 209
+ M ++E + E
Sbjct: 602 REQEEMTQEQEEKMGEQEE 620
Score = 31.6 bits (70), Expect = 0.84
Identities = 46/225 (20%), Positives = 94/225 (41%), Gaps = 20/225 (8%)
Query: 3 ISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDE 62
+ +L R++IS D + +++A L + ++ K R E+ + R + E
Sbjct: 214 VKQLEGEARDLISRLHDSWKFAGELEQA----LSAVATQKKKADRYIEELTKERDALSLE 269
Query: 63 EWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPD 122
+ R T+ E EL+E+ A+L+ K + + +E+Q + +K+ + P
Sbjct: 270 LY----RNTITDE----ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ 321
Query: 123 GAL----EETKVKLQQLEASYACQ--EKELLKVMKEYAFVTQLCEDQAL--YIKKYQETL 174
L + +LQ + A Q E EL + + +++ + + +K QE
Sbjct: 322 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 381
Query: 175 KKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARL 219
+KI E+ E + + E + EKE + E +K ++
Sbjct: 382 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 50.1 bits (118), Expect = 2e-06
Identities = 43/163 (26%), Positives = 84/163 (51%), Gaps = 11/163 (6%)
Query: 35 LLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKT 94
++ +QE E KI +E E ++++ + E E+ N+ E+ E+ E+ LE+ N+
Sbjct: 151 IVSVQE-EKKILAIELENLKSKLV---EVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRV 206
Query: 95 ---LVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQ-QLEASYACQEKELLKVM 150
V E+Q L + E + + +E+ K+K Q L + +++LLK +
Sbjct: 207 SMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKAL 266
Query: 151 KEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKL 193
E A +TQ E++ + ++Q+ +K++EE+LE L +E+ L
Sbjct: 267 DENAKLTQQLEEERI---QHQQKVKELEEQLENETLHKEIHNL 306
Score = 41.6 bits (96), Expect = 8e-04
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 36/147 (24%)
Query: 3 ISRLAQSKRNIISLNMDLERDTQRIDEA-------------------------NQKLLLK 37
+S LA + + +N++LE+D ++ E+ +Q+LL
Sbjct: 206 VSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKA 265
Query: 38 IQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMER----ERALQELEEETARLE---- 89
+ E Q+LE E IQ + V++ E + EN T + ++ L+ LEE+ LE
Sbjct: 266 LDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELELKYQ 325
Query: 90 ---RKNKTLVHSITELQQKLTRKSQKI 113
K + L HS+ ELQ+++ + +
Sbjct: 326 NSEEKARNLKHSVDELQKRVNQSENSV 352
>gi|50511340 shootin1 isoform b [Homo sapiens]
Length = 456
Score = 50.1 bits (118), Expect = 2e-06
Identities = 43/163 (26%), Positives = 84/163 (51%), Gaps = 11/163 (6%)
Query: 35 LLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKT 94
++ +QE E KI +E E ++++ + E E+ N+ E+ E+ E+ LE+ N+
Sbjct: 151 IVSVQE-EKKILAIELENLKSKLV---EVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRV 206
Query: 95 ---LVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQ-QLEASYACQEKELLKVM 150
V E+Q L + E + + +E+ K+K Q L + +++LLK +
Sbjct: 207 SMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKAL 266
Query: 151 KEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKL 193
E A +TQ E++ + ++Q+ +K++EE+LE L +E+ L
Sbjct: 267 DENAKLTQQLEEERI---QHQQKVKELEEQLENETLHKEIHNL 306
Score = 41.6 bits (96), Expect = 8e-04
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 36/147 (24%)
Query: 3 ISRLAQSKRNIISLNMDLERDTQRIDEA-------------------------NQKLLLK 37
+S LA + + +N++LE+D ++ E+ +Q+LL
Sbjct: 206 VSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKA 265
Query: 38 IQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMER----ERALQELEEETARLE---- 89
+ E Q+LE E IQ + V++ E + EN T + ++ L+ LEE+ LE
Sbjct: 266 LDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELELKYQ 325
Query: 90 ---RKNKTLVHSITELQQKLTRKSQKI 113
K + L HS+ ELQ+++ + +
Sbjct: 326 NSEEKARNLKHSVDELQKRVNQSENSV 352
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 49.7 bits (117), Expect = 3e-06
Identities = 45/188 (23%), Positives = 90/188 (47%), Gaps = 13/188 (6%)
Query: 37 KIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLV 96
K QE+EDK+ R E +I + E++ W +E + E+E QE EE+ + E K +
Sbjct: 564 KRQEQEDKMWRQEEKIREQ----EEKVWRQEEKIR-EQEEKRQEQEEKMWKQEEKIREQE 618
Query: 97 HSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFV 156
I E ++K+ + +KI E+ + +E + K+ + E C+++E ++ +E +
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMT-----QEQEEKMGEQEEK-MCEQEEKMQEQEETMWR 672
Query: 157 TQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKT 216
+ E KK +E +KI E+ E + + E E+E Q E ++
Sbjct: 673 QE--EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Query: 217 ARLFSKKI 224
+++ +++
Sbjct: 731 EKMWEQEV 738
Score = 45.8 bits (107), Expect = 4e-05
Identities = 45/199 (22%), Positives = 90/199 (45%), Gaps = 21/199 (10%)
Query: 16 LNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEE---WEKENRTTM 72
LN E R +E Q+ KIQE+E+KI+ E +I + + +E WEKE +
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK-MR 352
Query: 73 ERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKL 132
+E + E EE+ R E + ++ + K +KI E+ E+ K++
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH----EQEKIRE 408
Query: 133 QQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEEL--EALFLEREV 190
Q+ + QE+E ++ ++ ++Q + + +E +++ EE++ + + R+
Sbjct: 409 QEEKR----QEEEKIREQEKR-------QEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 191 SKLVSMNPVEKEHTSQNNE 209
K+ + +E Q E
Sbjct: 458 EKIHEQEKIREEEKRQEQE 476
Score = 45.8 bits (107), Expect = 4e-05
Identities = 33/158 (20%), Positives = 78/158 (49%), Gaps = 7/158 (4%)
Query: 21 ERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQE 80
E Q +E K KI+E+E+KIQ E +I + ++E+ ++ T E+E + E
Sbjct: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE-----QEEKIREQEEMTQEQEEKMGE 651
Query: 81 LEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQS--SPDGALEETKVKLQQLEAS 138
EE+ E K + ++ ++K+ + +KI E+ + ++E + K+ + E
Sbjct: 652 QEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 711
Query: 139 YACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKK 176
QE+++ + ++ + +Q + +++ +E +++
Sbjct: 712 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 42.0 bits (97), Expect = 6e-04
Identities = 39/171 (22%), Positives = 84/171 (49%), Gaps = 22/171 (12%)
Query: 22 RDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWE--KENRTTMERERALQ 79
R ++I E +K QE+E+K+ + E +I + ++++E + ++ E+E Q
Sbjct: 588 RQEEKIREQEEKR----QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 80 ELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASY 139
E EE+ E K + E ++ + R+ +KI E+ + E + K+++ E
Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK-----IREQEEKIREQEEMM 698
Query: 140 ACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREV 190
QE+++ + + ++CE + +K QE +K+ + E ++ E+EV
Sbjct: 699 QEQEEKMWEQEE------KMCEQE----EKMQEQEEKMRRQEEKMW-EQEV 738
Score = 40.8 bits (94), Expect = 0.001
Identities = 49/215 (22%), Positives = 94/215 (43%), Gaps = 16/215 (7%)
Query: 5 RLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEW 64
++ + + I + R ++I E KI+E E+K Q E Q + E EE
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQE-----KIRE-EEKRQEQEEMWRQEEKIHEQEEI 491
Query: 65 EKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQ--SSPD 122
++ E+E +++ EE+ R E K + I E ++K+ R+ +KI E+ +
Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Query: 123 GALEETKV----KLQQLEASYACQEKELL----KVMKEYAFVTQLCEDQALYIKKYQETL 174
E+ K+ K Q+ E QE+++ KV ++ + + E + +K +
Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611
Query: 175 KKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNE 209
+KI E+ E + + E + E+E +Q E
Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE 646
Score = 35.4 bits (80), Expect = 0.058
Identities = 37/183 (20%), Positives = 79/183 (43%), Gaps = 14/183 (7%)
Query: 40 EREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQEL------------EEETAR 87
E+E+KI+ LE ++ + + E EE +E E+E+ ++ +EE R
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
Query: 88 LERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELL 147
+ K Q+K+ + ++ E + + E + +Q E + QE+++
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE-QEEKIR 506
Query: 148 KVMKEYAFVTQLCEDQALYIKKYQETLKKIEEEL-EALFLEREVSKLVSMNPVEKEHTSQ 206
K ++ + +Q I++ +E + + EE++ E + RE K+ + +E Q
Sbjct: 507 KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 207 NNE 209
E
Sbjct: 567 EQE 569
Score = 32.3 bits (72), Expect = 0.50
Identities = 48/238 (20%), Positives = 101/238 (42%), Gaps = 31/238 (13%)
Query: 5 RLAQSKRNIISLNM-DLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLV---- 59
+L +S+++ I LN+ +L+R +R KLLL Q+ + + L E+ +
Sbjct: 231 QLVESEKSEIQLNVKELKRKLERA-----KLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 60 -EDEEWEKENRTTMER-----------ERALQELEEETARLERKNKTLVHSITELQQKLT 107
E+E W + N+ E+ E +QE EE+ E K + + ++ +
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Query: 108 RKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYI 167
K +K+ E+ + +E K++ Q+ E + +EK M+ + E++ +
Sbjct: 346 EKEEKMRRQEEMMWE---KEEKMRRQE-EMMWEKEEK-----MRRQEEMMWEKEEKIREL 396
Query: 168 KKYQETLKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKIF 225
++ +KI E+ E E ++ + E + Q + ++ R KK++
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Score = 31.6 bits (70), Expect = 0.84
Identities = 46/225 (20%), Positives = 94/225 (41%), Gaps = 20/225 (8%)
Query: 3 ISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDE 62
+ +L R++IS D + +++A L + ++ K R E+ + R + E
Sbjct: 153 VKQLEGEARDLISRLHDSWKFAGELEQA----LSAVATQKKKADRYIEELTKERDALSLE 208
Query: 63 EWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPD 122
+ R T+ E EL+E+ A+L+ K + + +E+Q + +K+ + P
Sbjct: 209 LY----RNTITDE----ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ 260
Query: 123 GAL----EETKVKLQQLEASYACQ--EKELLKVMKEYAFVTQLCEDQAL--YIKKYQETL 174
L + +LQ + A Q E EL + + +++ + + +K QE
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Query: 175 KKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARL 219
+KI E+ E + + E + EKE + E +K ++
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,740,799
Number of Sequences: 37866
Number of extensions: 432086
Number of successful extensions: 7661
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 279
Number of HSP's successfully gapped in prelim test: 824
Number of HSP's that attempted gapping in prelim test: 3702
Number of HSP's gapped (non-prelim): 3221
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.