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Search of human proteins with 33356179
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33356179 transcription termination factor, RNA polymerase I
[Homo sapiens]
(905 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33356179 transcription termination factor, RNA polymerase I [... 1799 0.0
gi|215599992 cyclin D binding myb-like transcription factor 1 is... 112 2e-24
gi|215599981 cyclin D binding myb-like transcription factor 1 is... 112 2e-24
gi|215599967 cyclin D binding myb-like transcription factor 1 is... 112 2e-24
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 65 3e-10
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 59 2e-08
gi|104526627 triadin [Homo sapiens] 54 9e-07
gi|87299628 biorientation of chromosomes in cell division 1-like... 50 9e-06
gi|32528306 replication factor C large subunit [Homo sapiens] 49 3e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 48 4e-05
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 47 8e-05
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 47 8e-05
gi|33356550 G patch domain containing 4 isoform 2 [Homo sapiens] 47 1e-04
gi|33356552 G patch domain containing 4 isoform 1 [Homo sapiens] 47 1e-04
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 47 1e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 46 1e-04
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 46 2e-04
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 46 2e-04
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 45 2e-04
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 45 2e-04
gi|111607441 hypothetical protein LOC400506 [Homo sapiens] 45 3e-04
gi|50962882 G patch domain containing 8 [Homo sapiens] 45 3e-04
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 45 4e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 44 7e-04
gi|4557509 cylicin 2 [Homo sapiens] 44 7e-04
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 44 7e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 44 7e-04
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 44 7e-04
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 44 7e-04
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 44 7e-04
>gi|33356179 transcription termination factor, RNA polymerase I
[Homo sapiens]
Length = 905
Score = 1799 bits (4660), Expect = 0.0
Identities = 905/905 (100%), Positives = 905/905 (100%)
Query: 1 MEGESSRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQ 60
MEGESSRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQ
Sbjct: 1 MEGESSRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQ 60
Query: 61 HLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFR 120
HLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFR
Sbjct: 61 HLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFR 120
Query: 121 KDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWES 180
KDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWES
Sbjct: 121 KDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWES 180
Query: 181 QRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGS 240
QRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGS
Sbjct: 181 QRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGS 240
Query: 241 QAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVG 300
QAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVG
Sbjct: 241 QAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVG 300
Query: 301 SEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEG 360
SEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEG
Sbjct: 301 SEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEG 360
Query: 361 SQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFD 420
SQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFD
Sbjct: 361 SQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFD 420
Query: 421 SVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHNVETAEDSEIRYLSAD 480
SVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHNVETAEDSEIRYLSAD
Sbjct: 421 SVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHNVETAEDSEIRYLSAD 480
Query: 481 SGDADDSDADLGSAVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFS 540
SGDADDSDADLGSAVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFS
Sbjct: 481 SGDADDSDADLGSAVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFS 540
Query: 541 VKENKQLEKNVEDFLALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPW 600
VKENKQLEKNVEDFLALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPW
Sbjct: 541 VKENKQLEKNVEDFLALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPW 600
Query: 601 KLIYYRAKKMFDVNNYKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQI 660
KLIYYRAKKMFDVNNYKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQI
Sbjct: 601 KLIYYRAKKMFDVNNYKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQI 660
Query: 661 SSQRNRGAWSKSETRKLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGI 720
SSQRNRGAWSKSETRKLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGI
Sbjct: 661 SSQRNRGAWSKSETRKLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGI 720
Query: 721 SWVEVEAKVQTRNWMQCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDT 780
SWVEVEAKVQTRNWMQCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDT
Sbjct: 721 SWVEVEAKVQTRNWMQCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDT 780
Query: 781 NEIDWEDLASAIGDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKEKLE 840
NEIDWEDLASAIGDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKEKLE
Sbjct: 781 NEIDWEDLASAIGDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKEKLE 840
Query: 841 KMMEKKGTKIQTPAAPKQVFPFRDIFYYEDDSEGEDIEKESEGQAPCMAHACNSSTLGGQ 900
KMMEKKGTKIQTPAAPKQVFPFRDIFYYEDDSEGEDIEKESEGQAPCMAHACNSSTLGGQ
Sbjct: 841 KMMEKKGTKIQTPAAPKQVFPFRDIFYYEDDSEGEDIEKESEGQAPCMAHACNSSTLGGQ 900
Query: 901 GRWII 905
GRWII
Sbjct: 901 GRWII 905
>gi|215599992 cyclin D binding myb-like transcription factor 1
isoform a [Homo sapiens]
Length = 760
Score = 112 bits (279), Expect = 2e-24
Identities = 84/314 (26%), Positives = 142/314 (45%), Gaps = 40/314 (12%)
Query: 496 KQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKNVEDFL 555
+QL E P + + S + + + E +G K G +S +E L N+E +L
Sbjct: 114 EQLDEISP-LGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYL 172
Query: 556 ALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPWKLIYYRAKKMFDVNN 615
GI+ A ++++ E K F I + RP +Y R +M+D N
Sbjct: 173 KARGIKDATEIIFEMSKDERKD----------FYRTIAWGLNRPLFAVYRRVLRMYDDRN 222
Query: 616 YKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQISSQRNRGAWSKSETR 675
+ G+Y+ + EKLK GNDW TIG + RS+ SV + + N G W++ E +
Sbjct: 223 HVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEK 282
Query: 676 KLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGISWVEVEAKVQTRNWM 735
+L + V E L P ++ + +G+SW V +V TR+
Sbjct: 283 RLAEVVHE--LTSTEPGDI---------------------VTQGVSWAAVAERVGTRSEK 319
Query: 736 QCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDTNEIDWEDLASAIGDV 795
QC+SKW L + + G +++LI R+ E++V D N+I+W+ LA V
Sbjct: 320 QCRSKWLNYLNWKQSGGTEW-----TKEDEINLILRIAELDVADENDINWDLLAEGWSSV 374
Query: 796 -PPSYVQTKFSRLK 808
P ++++K+ +K
Sbjct: 375 RSPQWLRSKWWTIK 388
>gi|215599981 cyclin D binding myb-like transcription factor 1
isoform b [Homo sapiens]
Length = 672
Score = 112 bits (279), Expect = 2e-24
Identities = 84/314 (26%), Positives = 142/314 (45%), Gaps = 40/314 (12%)
Query: 496 KQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKNVEDFL 555
+QL E P + + S + + + E +G K G +S +E L N+E +L
Sbjct: 26 EQLDEISP-LGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYL 84
Query: 556 ALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPWKLIYYRAKKMFDVNN 615
GI+ A ++++ E K F I + RP +Y R +M+D N
Sbjct: 85 KARGIKDATEIIFEMSKDERKD----------FYRTIAWGLNRPLFAVYRRVLRMYDDRN 134
Query: 616 YKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQISSQRNRGAWSKSETR 675
+ G+Y+ + EKLK GNDW TIG + RS+ SV + + N G W++ E +
Sbjct: 135 HVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEK 194
Query: 676 KLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGISWVEVEAKVQTRNWM 735
+L + V E L P ++ + +G+SW V +V TR+
Sbjct: 195 RLAEVVHE--LTSTEPGDI---------------------VTQGVSWAAVAERVGTRSEK 231
Query: 736 QCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDTNEIDWEDLASAIGDV 795
QC+SKW L + + G +++LI R+ E++V D N+I+W+ LA V
Sbjct: 232 QCRSKWLNYLNWKQSGGTEW-----TKEDEINLILRIAELDVADENDINWDLLAEGWSSV 286
Query: 796 -PPSYVQTKFSRLK 808
P ++++K+ +K
Sbjct: 287 RSPQWLRSKWWTIK 300
>gi|215599967 cyclin D binding myb-like transcription factor 1
isoform a [Homo sapiens]
Length = 760
Score = 112 bits (279), Expect = 2e-24
Identities = 84/314 (26%), Positives = 142/314 (45%), Gaps = 40/314 (12%)
Query: 496 KQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKNVEDFL 555
+QL E P + + S + + + E +G K G +S +E L N+E +L
Sbjct: 114 EQLDEISP-LGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYL 172
Query: 556 ALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPWKLIYYRAKKMFDVNN 615
GI+ A ++++ E K F I + RP +Y R +M+D N
Sbjct: 173 KARGIKDATEIIFEMSKDERKD----------FYRTIAWGLNRPLFAVYRRVLRMYDDRN 222
Query: 616 YKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQISSQRNRGAWSKSETR 675
+ G+Y+ + EKLK GNDW TIG + RS+ SV + + N G W++ E +
Sbjct: 223 HVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEK 282
Query: 676 KLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGISWVEVEAKVQTRNWM 735
+L + V E L P ++ + +G+SW V +V TR+
Sbjct: 283 RLAEVVHE--LTSTEPGDI---------------------VTQGVSWAAVAERVGTRSEK 319
Query: 736 QCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDTNEIDWEDLASAIGDV 795
QC+SKW L + + G +++LI R+ E++V D N+I+W+ LA V
Sbjct: 320 QCRSKWLNYLNWKQSGGTEW-----TKEDEINLILRIAELDVADENDINWDLLAEGWSSV 374
Query: 796 -PPSYVQTKFSRLK 808
P ++++K+ +K
Sbjct: 375 RSPQWLRSKWWTIK 388
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 65.1 bits (157), Expect = 3e-10
Identities = 82/404 (20%), Positives = 150/404 (37%), Gaps = 37/404 (9%)
Query: 58 DFQHLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPK 117
D I+ PL S DE A +++++ ++ E DEE K+ N P
Sbjct: 531 DLDAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEADEEELARRREARKQEQANNPF 590
Query: 118 HFRKD---------------VDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSK 162
+ + + VV +D+S+ K+P P +D++ L + H+ + K
Sbjct: 591 YIKSSPSPQKRYQDTPGVEHIPVVQIDLSVPLKVPGLPMSDQYVKLEEERRHRQKLEKDK 650
Query: 163 VREK---KNKKHQRKAASWESQRARDTLP--QSESHQEESWLSVGPGGEITELPASAHKN 217
R+K K KK +R+ +S ++ D P Q + EE + P E + P ++
Sbjct: 651 RRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDPNDPYRA 710
Query: 218 KSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKK 277
K ++ E +P E ++ P V + P+ HK+K +
Sbjct: 711 LDIDLDKPLADSE----KLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERD 766
Query: 278 KKKKKSNHQEFEALAM-------PEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKN 330
K+KKK ++ E L P + + V + + GE
Sbjct: 767 KEKKKEKEKKAEDLDFWLSTTPPPAPAPAPAPVPSTDECEDAKTEAQGEEDDAEGQDQDK 826
Query: 331 KSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSK 390
KS K KKK + +E E + P GS+ + G G E +S
Sbjct: 827 KSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAA------GEPVQNGAPEEEQLPPESS 880
Query: 391 KRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVK 434
L +++ D ++S+ T+ +E + + +G++
Sbjct: 881 YSLLAENSYVKMTCDIRGSLQEDSQVTVAIVLENRSSSILKGME 924
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 59.3 bits (142), Expect = 2e-08
Identities = 72/328 (21%), Positives = 130/328 (39%), Gaps = 49/328 (14%)
Query: 58 DFQHLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPK 117
D I+ PL S DE A +++++ ++ E DEE K+ N P
Sbjct: 622 DLDAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEADEEELARRREARKQEQANNPF 681
Query: 118 HFRKD---------------VDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSK 162
+ + + VV +D+S+ K+P P +D++ L + H+ + K
Sbjct: 682 YIKSSPSPQKRYQDTPGVEHIPVVQIDLSVPLKVPGLPMSDQYVKLEEERRHRQKLEKDK 741
Query: 163 VREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEI----TELPASAHKNK 218
R+K+ +K ++ +R +LP +ES ++ + P ++ E+P +A
Sbjct: 742 RRKKRKEKEKK------GKRRHSSLP-TESDED-----IAPAQQVDIVTEEMPENA---L 786
Query: 219 SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKK 278
+ K N Y L + +Q+ + T ++P+ P +KKSKK
Sbjct: 787 PSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTE--TSKSPEKDVPMVEKKSKKP 844
Query: 279 KKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKK 338
KKK+ H+E E + + + +P H + + K KKK KK
Sbjct: 845 KKKEKKHKE------KERDKEKKKEKEKKKSPKPKKKKHRK-----EKEERTKGKKKSKK 893
Query: 339 SNHQEFEAVAMPESLESAYPEGSQVGSE 366
EA P +++ PE Q+ E
Sbjct: 894 QPPGSEEAAGEP--VQNGAPEEEQLPPE 919
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 53.5 bits (127), Expect = 9e-07
Identities = 79/366 (21%), Positives = 135/366 (36%), Gaps = 56/366 (15%)
Query: 129 DMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNK-------KHQRKAASWESQ 181
+ I+ K+ K K + + + + +A H + EKK K K Q+KA + E
Sbjct: 155 ERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKS 214
Query: 182 RARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAM----- 236
+ QE+ + E+ + P+ + + K+K S + + + A
Sbjct: 215 EEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMI 274
Query: 237 ---------PEGSQAGREAGTDMQESQPT---------VGLDDETPQLLGPTHKKKSKKK 278
P S A Q S+PT G + + + KKK K+
Sbjct: 275 DIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKED 334
Query: 279 KKKKSNH------QEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKS 332
KKKS ++ E E Q ++ A + + PA + K
Sbjct: 335 IKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKG 394
Query: 333 KKKKKKSNHQEFEAVAMPESLESAYPEGSQVGS-------EVGTVEGSTALKGFKESNST 385
KK++KK H E A E + P QV + E+G V A+ G KE +T
Sbjct: 395 KKQEKKEKHVE---PAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTT 451
Query: 386 K------KKSKKRKLTSVKRAR--VSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRP 437
K +K K K +S+ + + + G + VP+ E + D M + G + +P
Sbjct: 452 KTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKE--PETKKDEKMSKAGKEVKP 509
Query: 438 RQKKTQ 443
+ + Q
Sbjct: 510 KPPQLQ 515
Score = 38.1 bits (87), Expect = 0.037
Identities = 85/440 (19%), Positives = 157/440 (35%), Gaps = 69/440 (15%)
Query: 16 DKKKKKCSIHKERPQ----KHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSR 71
DK+K S H+++ Q ++ +IF L QS I PL +
Sbjct: 252 DKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPA-------------IPPPLPTEQ 298
Query: 72 ICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMS 131
T + + +K +++ + +V E +KE+I +K +D
Sbjct: 299 ASRPTPASPALEEKEGEKKKAEKKVTSETKKK----EKEDIK------KKSEKETAID-- 346
Query: 132 IEQKLPRKPKTDK---FQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLP 188
+E+K P K K ++ A++ A K E + KK + ++ + ++ + P
Sbjct: 347 VEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEP 406
Query: 189 QSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGT 248
+E S S TE S KK E T + + + + T
Sbjct: 407 AKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKT 466
Query: 249 D--MQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGAD 306
+++ +P G +++ P L + K +K K+ + +G +
Sbjct: 467 SSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQI 526
Query: 307 MQESRPAVG----LHGETAGIPAPAY-------------------KNKSKKKKKKSNHQE 343
+E++PA+ +H + P K K KK+ H+E
Sbjct: 527 KKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHRE 586
Query: 344 FEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESN----------STKKKSKK-- 391
E ++ P+G+ +E G + + K KE ST+K+S +
Sbjct: 587 REPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKESLQLH 646
Query: 392 RKLTSVKRARVSGDDFSVPS 411
+ K ARVS D VP+
Sbjct: 647 NVTKAEKPARVSKDVEDVPA 666
Score = 37.4 bits (85), Expect = 0.064
Identities = 76/379 (20%), Positives = 148/379 (39%), Gaps = 53/379 (13%)
Query: 190 SESHQEESWLSVGPGGEITELPA---SAHKNKSKKKKKKSSNREYETLAMPEGSQAGREA 246
SE +++ GEI E P HK+K++K++K R+ +T + + G+E
Sbjct: 116 SEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPE--RKIQTKVTHKEKEKGKEK 173
Query: 247 GTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEV-GA 305
+ ++ + ++ + P K +K++KK K+ + E + EV G
Sbjct: 174 VREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEE--------KTKKEVKGG 225
Query: 306 DMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGS---- 361
++ + E P+ + + K+K S H++ + A + + G
Sbjct: 226 KQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPG 285
Query: 362 ---QVGSEVGTVEGS---TALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSE 415
+ + T + S A +E KKK++K K+TS + + D + K+ +
Sbjct: 286 QSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEK-KVTSETKKKEKED---IKKKSEK 341
Query: 416 STLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHNVETAEDSEIR 475
T D VE E G S +Q K +A + +E + +T + +E+
Sbjct: 342 ETAID-VE----KKEPGKASETKQGTV------KIAAQAAAKKDEKKEDSKKTKKPAEVE 390
Query: 476 YLSADSGDADDSDADLGSAVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIK 535
+ + + + K+ + +P+ K T ER KE + V+IK
Sbjct: 391 QPKGKKQEKKEKHVEPAKSPKK-EHSVPSDKQVKAKT---------ERAKE-EIGAVSIK 439
Query: 536 F---GKFSVKENKQLEKNV 551
GK K K +E+ +
Sbjct: 440 KAVPGKKEEKTTKTVEQEI 458
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 50.1 bits (118), Expect = 9e-06
Identities = 109/531 (20%), Positives = 189/531 (35%), Gaps = 74/531 (13%)
Query: 4 ESSRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLI 63
E + E T ++ ++ I E PQK + + L + S+ K L+
Sbjct: 665 EGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKS-------LL 717
Query: 64 SSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDV 123
+K S+ E S K K +Y + + G L E ++ +K
Sbjct: 718 KKEVKSSKEKPEREKTPSEDKLSVKHKYKG-DCMHKTGDETELHSSEKGLKVEENIQKQS 776
Query: 124 DVVCVDMSIEQKLPRKPK---TDKFQVLAKSHAHKSEAL---HSKVREKKNKKHQRKAAS 177
+S + K RK K K VL K SE + VR++ NKK +R +A
Sbjct: 777 QQT--KLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAE 834
Query: 178 -----WESQRARDTLPQSES-----------HQEESWLSVGPGGEITELPAS------AH 215
+S+R+ D+ Q +S + ES+ + T + ++ H
Sbjct: 835 KTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVH 894
Query: 216 KNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKS 275
K K + K ++ + +G Q + T++QE T P T + S
Sbjct: 895 KEKRRTKSLLEEKLVLKSKSKTQGKQV-KVVETELQEGA-TKQATTPKPDKEKNTEENDS 952
Query: 276 KKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKK 335
+K++K K + FE + + S Q+ A +P K KS K
Sbjct: 953 EKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDS------SHRAKLPLAKEKYKSDKD 1006
Query: 336 --------------KKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKE 381
K +S + + + +S +G +V S G+++L K
Sbjct: 1007 STSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKL 1066
Query: 382 SN----------STKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEE 431
S S + + KL + + SG P K+ + TL E E
Sbjct: 1067 SRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEP 1126
Query: 432 GVKSRPRQKKTQACLASKHVQEAPRLEPAN-EEHNVETAEDSEIRYLSADS 481
GV++ KTQ + Q+ ++ N ++ T + E+R +ADS
Sbjct: 1127 GVENVFEVSKTQDNRNNNSQQD---IDSENMKQKTSATVQKDELRTCTADS 1174
Score = 34.7 bits (78), Expect = 0.41
Identities = 70/407 (17%), Positives = 150/407 (36%), Gaps = 66/407 (16%)
Query: 46 QSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKKRKKRRYSALE---------- 95
+ ++ KKRKKD +++ + KK + +++ T + +K + S+ +
Sbjct: 567 EKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSE 626
Query: 96 --------------VDEEAGVTVVLVDKENINNTP---KHFRKDVDVVCVDMSIEQK--L 136
VDE + + + + +TP + +++ D V +E+
Sbjct: 627 PSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEIC 686
Query: 137 PRKPKTDKFQVLAKSHAHK--SEALHSKVREKKNKKHQRKAASWESQRARDTL------- 187
+P+ K + + H K SE H K KK K ++ E + D L
Sbjct: 687 TEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYK 746
Query: 188 --------PQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEG 239
++E H E L V I + + K ++KS +R L++
Sbjct: 747 GDCMHKTGDETELHSSEKGLKVEE--NIQKQSQQTKLSSDDKTERKSKHRNERKLSVL-- 802
Query: 240 SQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQ--------EFEAL 291
+ G+ + ++ V ++ + K K++ K ++ S+ + + +
Sbjct: 803 GKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGI 862
Query: 292 AMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPE 351
+ S+ SE DM + L P +K++ KS +E +
Sbjct: 863 TLQRRSESYSEDKCDMDSTNMDSNL--------KPEEVVHKEKRRTKSLLEEKLVLKSKS 914
Query: 352 SLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVK 398
+ + + + G + +T K KE N+ + S+K++ + V+
Sbjct: 915 KTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVE 961
Score = 33.9 bits (76), Expect = 0.70
Identities = 76/417 (18%), Positives = 155/417 (37%), Gaps = 63/417 (15%)
Query: 149 AKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESW---LSVGPGG 205
A++ S A S+ KK S + +R + + E +S L P
Sbjct: 218 ARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKS 277
Query: 206 E-ITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETP 264
E ++LP + K+ K+ +N + + S + TD E +P
Sbjct: 278 EEFSDLPCPVEEIKNYTKEH--NNLILLNKDVQQESSEQKNKSTDKGEKKPD-------- 327
Query: 265 QLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIP 324
+++K +KK+KK+ ++F+ E +Q +V + Q E +
Sbjct: 328 -----SNEKGERKKEKKEKTEKKFDHSKKSEDTQ---KVKDEKQAKEK------EVESLK 373
Query: 325 APAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEV-GTVEGSTALKGFKESN 383
P+ KN +K K + ++F S + S+V G + + + + +
Sbjct: 374 LPSEKNSNKAKTVEGTKEDF----------------SLIDSDVDGLTDITVSSVHTSDLS 417
Query: 384 STKKKSKKRKLT--SVKRARVSGDDFSVPSKNSEST-LFDSVEGDGAMMEEGVKSRPRQK 440
S ++ +++ +T S++ ++ DD +N T DS EG + +P
Sbjct: 418 SFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKP--- 474
Query: 441 KTQACLASKHVQEAPRLEPANEEHNVETAEDSEIRYL-------SADSGDADDSDADLGS 493
L SK+ ++ E E+ A++ E R L + ++ S
Sbjct: 475 ----YLYSKYYSDSDD-ELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSS 529
Query: 494 AVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKN 550
K ++++ +T +++ E KE K + K K+++ +E+N
Sbjct: 530 KTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEEN 586
Score = 33.1 bits (74), Expect = 1.2
Identities = 36/158 (22%), Positives = 65/158 (41%), Gaps = 26/158 (16%)
Query: 345 EAVAMPESLESAYPEG-SQVGSEVGTVEGSTALK--GFKESNSTKKKSKKRKLTSVKRAR 401
E +A PESL P G +++ E V S ++ GF+ + +S +
Sbjct: 2685 EILAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSESYNK--------- 2735
Query: 402 VSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASK------------ 449
G+ S N+E+ SVE D +EE + P++K+ Q L+S+
Sbjct: 2736 --GEISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDS 2793
Query: 450 HVQEAPRLEPANEEHNVETAEDSEIRYLSADSGDADDS 487
++ A R P E H+ + ++ L S + + +
Sbjct: 2794 RIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNST 2831
>gi|32528306 replication factor C large subunit [Homo sapiens]
Length = 1147
Score = 48.5 bits (114), Expect = 3e-05
Identities = 101/474 (21%), Positives = 180/474 (37%), Gaps = 76/474 (16%)
Query: 94 LEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHA 153
L DEE T+ ++D+E K RKD + S++ L + A+ H
Sbjct: 219 LHEDEEFARTLAMLDEEP---KTKKARKDTEAGETFSSVQANLSK----------AEKHK 265
Query: 154 HKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPAS 213
+ + ++V +++ RK + +ES + +S+ H + S +G E++ AS
Sbjct: 266 YPHKVKTAQVSDERKSYSPRKQSKYESSK------ESQQHSKSSADKIG---EVSSPKAS 316
Query: 214 AHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKK 273
+ K K+K++SS +E E +A A + G + +TP+ + K
Sbjct: 317 S-KLAIMKRKEESSYKEIEPVASKRKENAIKLKG------------ETKTPKKTKSSPAK 363
Query: 274 KS----KKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYK 329
K + +KK++N+Q + + EG + GL G+ +
Sbjct: 364 KESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLESIER 423
Query: 330 NKSK------------KKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALK 377
+++K KK+N+ + + A G+++ E G + +
Sbjct: 424 DEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIRTMP 483
Query: 378 GFK---ESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVK 434
G K E + K+ KL + V G PSK E K
Sbjct: 484 GKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKE---------------SESKK 528
Query: 435 SRPRQKK-TQACLASKHVQEAPRLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGS 493
SRP K+ + A K + E+ ET+ DS+ R L+ DS + +
Sbjct: 529 SRPTSKRDSLAKTIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVD 588
Query: 494 AVK--QLQEFIPNIKDRA-TSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKEN 544
K L+ I D++ + + R R+ + E K KFGKFS K++
Sbjct: 589 KYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHA---KFGKFSGKDD 639
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 48.1 bits (113), Expect = 4e-05
Identities = 84/398 (21%), Positives = 148/398 (37%), Gaps = 51/398 (12%)
Query: 27 ERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKKR 86
E P+ +S + R+SS + ++KK+KKD + R + ++ K
Sbjct: 166 EPPKPYS--LVRESSSSRSPTPKQKKKKKKKD----------RGRRSESSSPRRERKKSS 213
Query: 87 KKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQ 146
KK+++ + ++ +++ + TPK RK D P+ + +
Sbjct: 214 KKKKHRSESESKK---------RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST 264
Query: 147 VLAKSHAHKSEALHSKVREKKNKKHQ-----RKAASWESQRARDTLPQSESHQEESWLSV 201
+ A S+ S+ R K H R + +R P SE +
Sbjct: 265 --SADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPS 322
Query: 202 GPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGRE--------AGTDMQES 253
P T+ P+S +++K K KK+KS+ R + PE S G E A
Sbjct: 323 SPE-TATKQPSSPYEDKDKDKKEKSATRPSPS---PERSSTGPEPPAPTPLLAERHGGSP 378
Query: 254 QP--TVGLDDE---TPQLLGPTHKKKSKKKKKKKSNHQEFEAL-AMPEGSQVGSEVGADM 307
QP T L E P PT + K +K E+ P+ ++V +
Sbjct: 379 QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438
Query: 308 QESR--PAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGS 365
+ + PA G H E + P ++ + K+ KS H + M S A + + S
Sbjct: 439 ESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKS-HSHTPSRRMGRSRSPATAKRGRSRS 497
Query: 366 EVGTVEGSTALKG--FKESNSTKKKSKKRKLTSVKRAR 401
T G + + ++ S S ++ + R R+R
Sbjct: 498 RTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSR 535
Score = 38.1 bits (87), Expect = 0.037
Identities = 40/150 (26%), Positives = 60/150 (40%), Gaps = 18/150 (12%)
Query: 201 VGPGGE---------ITELPASAHKNKSKKKKKKSS---NREYETLAMPEGSQAGREAGT 248
V PGG+ +TE A N+ K ++ +++ + Y + + + REA
Sbjct: 103 VNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQ 162
Query: 249 DMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQ 308
E L E+ PT K+K KKKKKK + E+ + + S+
Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQK--KKKKKKDRGRRSESSSPRRERKKSSKKKKHRS 220
Query: 309 ESRPAVGLHGETAGIPAPAYKNKSKKKKKK 338
ES H P P K KSK KK+K
Sbjct: 221 ESESKKRKHRS----PTPKSKRKSKDKKRK 246
Score = 35.4 bits (80), Expect = 0.24
Identities = 46/244 (18%), Positives = 89/244 (36%), Gaps = 23/244 (9%)
Query: 165 EKKNKKHQRKAASWESQRARD---TLPQSESHQEESWLSVGPGGEITELPASAHKNKSKK 221
+ K++ R++ S S +D P+++S + S P LP + S K
Sbjct: 1586 DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA--LPRRSRSGSSSK 1643
Query: 222 KKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKK 281
+ S T + PE R A + S P K KS+ ++
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSS---------------PEPKTKSRTPPRR 1688
Query: 282 KSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGI--PAPAYKNKSKKKKKKS 339
+S+ E S+ + + H + + P PA K++S ++++ +
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748
Query: 340 NHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKR 399
+ + + S P G Q E + + S S++ S++R+ S R
Sbjct: 1749 SSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQ-RSRSR 1807
Query: 400 ARVS 403
+RV+
Sbjct: 1808 SRVT 1811
Score = 31.6 bits (70), Expect = 3.5
Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query: 793 GDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKEKLEKMMEKKGTKIQT 852
G+ P + + RL+A V K+ P+I+D+ + + L +LE+MME++G + Q
Sbjct: 31 GERPDYKGEEELRRLEAALV----KRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQ- 85
Query: 853 PAAPKQVFPFRDIFYYEDDSEGEDIEKESEGQAPCM 888
++V FR + +D + G ++E+ GQ P +
Sbjct: 86 -QIQEKVATFRLMLLEKDVNPGG--KEETPGQRPAV 118
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 47.0 bits (110), Expect = 8e-05
Identities = 55/245 (22%), Positives = 100/245 (40%), Gaps = 44/245 (17%)
Query: 162 KVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKK 221
K + +K KK + A +E + + + E H+E+ ++ +S+ K + KK
Sbjct: 35 KEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKL---------LSGSESSSKKRQRKK 85
Query: 222 KKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKK 281
K+KK S R S + ++ + +S +DE KK+ K++KKK
Sbjct: 86 KEKKKSGR------YSSSSSSSSDSSSSSSDS------EDE--------DKKQGKRRKKK 125
Query: 282 KSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNH 341
K+ + +M E + ++S+ + G+ SKK+K S
Sbjct: 126 KNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGL--------SKKRKMYSED 177
Query: 342 QEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRAR 401
+ + ++ ES Y E + + + E A + K+ KK SKK+K K+A
Sbjct: 178 KPLSSESLS---ESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKK----KKAA 230
Query: 402 VSGDD 406
S D
Sbjct: 231 SSSPD 235
Score = 40.4 bits (93), Expect = 0.008
Identities = 34/153 (22%), Positives = 69/153 (45%), Gaps = 4/153 (2%)
Query: 133 EQKLPRKPKTDKFQVLAKSHAHKSEALH-SKVREKKNKKHQRKAASWESQRARDTLPQSE 191
++K K K+ ++ + S + S + S+ +KK K ++K + + + ++ ++E
Sbjct: 82 QRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETE 141
Query: 192 SHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQ 251
S ++S + TE K SKK+K S ++ + ++ E +
Sbjct: 142 SDSKDSLKKKKKSKDGTEKEKDI-KGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKK 200
Query: 252 ESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSN 284
S+ ++T + HKK SKKKKKK ++
Sbjct: 201 SSEEREKATEKTKKK--KKHKKHSKKKKKKAAS 231
Score = 37.7 bits (86), Expect = 0.049
Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 23/174 (13%)
Query: 17 KKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDET 76
K+KKK + S S +E + +R+K+KK+ H S +S + +
Sbjct: 86 KEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSS----ESSMSETE 141
Query: 77 ANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKL 136
+++ +LKK+KK + E ++ D + ++ K + +D + +S + +
Sbjct: 142 SDSKDSLKKKKKSK-DGTEKEK---------DIKGLSKKRKMYSEDKPLSSESLSESEYI 191
Query: 137 PRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQS 190
K KS + +A ++KK+KKH +K + ++A + P S
Sbjct: 192 EEVRAKKK-----KSSEEREKATEKTKKKKKHKKHSKK----KKKKAASSSPDS 236
Score = 36.2 bits (82), Expect = 0.14
Identities = 40/203 (19%), Positives = 80/203 (39%), Gaps = 31/203 (15%)
Query: 26 KERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKK 85
K+ +KH ++ S +++ Q R+KK KK SS S ++++ KK
Sbjct: 60 KKELEKHREKLLSGSESSSKKRQ--RKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKK 117
Query: 86 RKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKF 145
+ KRR ++ + + + + ++ K +K D + I+ ++ +
Sbjct: 118 QGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSED 177
Query: 146 QVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGG 205
+ L+ +SE + +VR KK K + + + E + +
Sbjct: 178 KPLSSESLSESEYI-EEVRAKKKKSSEEREKATEKTKKK--------------------- 215
Query: 206 EITELPASAHKNKSKKKKKKSSN 228
HK SKKKKKK+++
Sbjct: 216 -------KKHKKHSKKKKKKAAS 231
Score = 30.8 bits (68), Expect = 6.0
Identities = 43/211 (20%), Positives = 76/211 (36%), Gaps = 39/211 (18%)
Query: 133 EQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSES 192
E+K+ K + + K + + + R+KK KK + +S S + + S+S
Sbjct: 52 EEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDS 111
Query: 193 HQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQE 252
E+ K K++KK NR +++ E+ E
Sbjct: 112 EDED--------------------KKQGKRRKKKKNRSHKS----------SESSMSETE 141
Query: 253 SQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRP 312
S L + G +K K KK+ + E + L+ S+ SE +++ +
Sbjct: 142 SDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSE--SEYIEEVRAKKK 199
Query: 313 AVGLHGETAGIPAPAYKNKSKKKKKKSNHQE 343
E A K+KKKKK H +
Sbjct: 200 KSSEEREKA-------TEKTKKKKKHKKHSK 223
Score = 30.4 bits (67), Expect = 7.8
Identities = 40/222 (18%), Positives = 85/222 (38%), Gaps = 18/222 (8%)
Query: 250 MQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQE 309
+Q S PT+ P+ K++ +KKKK EFE ++ ++++
Sbjct: 13 IQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFE-------EKMNENWKKELEK 65
Query: 310 SRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGT 369
R + +G + + K + KKK+KK + + + + S+ + + G
Sbjct: 66 HREKL-----LSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGK 120
Query: 370 VEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGD------DFSVPSKNSESTLFDSVE 423
+ K S S+ +++ S+K+ + S D D SK + D
Sbjct: 121 RRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPL 180
Query: 424 GDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHN 465
++ E R KK ++ + E + + +++H+
Sbjct: 181 SSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHS 222
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 47.0 bits (110), Expect = 8e-05
Identities = 55/245 (22%), Positives = 100/245 (40%), Gaps = 44/245 (17%)
Query: 162 KVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKK 221
K + +K KK + A +E + + + E H+E+ ++ +S+ K + KK
Sbjct: 45 KEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKL---------LSGSESSSKKRQRKK 95
Query: 222 KKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKK 281
K+KK S R S + ++ + +S +DE KK+ K++KKK
Sbjct: 96 KEKKKSGR------YSSSSSSSSDSSSSSSDS------EDE--------DKKQGKRRKKK 135
Query: 282 KSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNH 341
K+ + +M E + ++S+ + G+ SKK+K S
Sbjct: 136 KNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGL--------SKKRKMYSED 187
Query: 342 QEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRAR 401
+ + ++ ES Y E + + + E A + K+ KK SKK+K K+A
Sbjct: 188 KPLSSESLS---ESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKK----KKAA 240
Query: 402 VSGDD 406
S D
Sbjct: 241 SSSPD 245
Score = 40.4 bits (93), Expect = 0.008
Identities = 34/153 (22%), Positives = 69/153 (45%), Gaps = 4/153 (2%)
Query: 133 EQKLPRKPKTDKFQVLAKSHAHKSEALH-SKVREKKNKKHQRKAASWESQRARDTLPQSE 191
++K K K+ ++ + S + S + S+ +KK K ++K + + + ++ ++E
Sbjct: 92 QRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETE 151
Query: 192 SHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQ 251
S ++S + TE K SKK+K S ++ + ++ E +
Sbjct: 152 SDSKDSLKKKKKSKDGTEKEKDI-KGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKK 210
Query: 252 ESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSN 284
S+ ++T + HKK SKKKKKK ++
Sbjct: 211 SSEEREKATEKTKKK--KKHKKHSKKKKKKAAS 241
Score = 37.7 bits (86), Expect = 0.049
Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 23/174 (13%)
Query: 17 KKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDET 76
K+KKK + S S +E + +R+K+KK+ H S +S + +
Sbjct: 96 KEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSS----ESSMSETE 151
Query: 77 ANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKL 136
+++ +LKK+KK + E ++ D + ++ K + +D + +S + +
Sbjct: 152 SDSKDSLKKKKKSK-DGTEKEK---------DIKGLSKKRKMYSEDKPLSSESLSESEYI 201
Query: 137 PRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQS 190
K KS + +A ++KK+KKH +K + ++A + P S
Sbjct: 202 EEVRAKKK-----KSSEEREKATEKTKKKKKHKKHSKK----KKKKAASSSPDS 246
Score = 36.2 bits (82), Expect = 0.14
Identities = 40/203 (19%), Positives = 80/203 (39%), Gaps = 31/203 (15%)
Query: 26 KERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKK 85
K+ +KH ++ S +++ Q R+KK KK SS S ++++ KK
Sbjct: 70 KKELEKHREKLLSGSESSSKKRQ--RKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKK 127
Query: 86 RKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKF 145
+ KRR ++ + + + + ++ K +K D + I+ ++ +
Sbjct: 128 QGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSED 187
Query: 146 QVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGG 205
+ L+ +SE + +VR KK K + + + E + +
Sbjct: 188 KPLSSESLSESEYI-EEVRAKKKKSSEEREKATEKTKKK--------------------- 225
Query: 206 EITELPASAHKNKSKKKKKKSSN 228
HK SKKKKKK+++
Sbjct: 226 -------KKHKKHSKKKKKKAAS 241
Score = 30.8 bits (68), Expect = 6.0
Identities = 43/211 (20%), Positives = 76/211 (36%), Gaps = 39/211 (18%)
Query: 133 EQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSES 192
E+K+ K + + K + + + R+KK KK + +S S + + S+S
Sbjct: 62 EEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDS 121
Query: 193 HQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQE 252
E+ K K++KK NR +++ E+ E
Sbjct: 122 EDED--------------------KKQGKRRKKKKNRSHKS----------SESSMSETE 151
Query: 253 SQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRP 312
S L + G +K K KK+ + E + L+ S+ SE +++ +
Sbjct: 152 SDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSE--SEYIEEVRAKKK 209
Query: 313 AVGLHGETAGIPAPAYKNKSKKKKKKSNHQE 343
E A K+KKKKK H +
Sbjct: 210 KSSEEREKA-------TEKTKKKKKHKKHSK 233
Score = 30.4 bits (67), Expect = 7.8
Identities = 40/222 (18%), Positives = 85/222 (38%), Gaps = 18/222 (8%)
Query: 250 MQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQE 309
+Q S PT+ P+ K++ +KKKK EFE ++ ++++
Sbjct: 23 IQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFE-------EKMNENWKKELEK 75
Query: 310 SRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGT 369
R + +G + + K + KKK+KK + + + + S+ + + G
Sbjct: 76 HREKL-----LSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGK 130
Query: 370 VEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGD------DFSVPSKNSESTLFDSVE 423
+ K S S+ +++ S+K+ + S D D SK + D
Sbjct: 131 RRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPL 190
Query: 424 GDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHN 465
++ E R KK ++ + E + + +++H+
Sbjct: 191 SSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHS 232
>gi|33356550 G patch domain containing 4 isoform 2 [Homo sapiens]
Length = 370
Score = 46.6 bits (109), Expect = 1e-04
Identities = 49/215 (22%), Positives = 88/215 (40%), Gaps = 36/215 (16%)
Query: 130 MSIEQKLPR-KPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLP 188
++++ KL R + + F K + L S+ + K KK +R+ E A +
Sbjct: 165 ITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERND 224
Query: 189 QSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGT 248
E H P A +N K KKKK ++E + EG+ G E
Sbjct: 225 ADEKH-----------------PEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEK-- 265
Query: 249 DMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQ 308
+++ T GL + + T++ K KKKK+ +H+E + + EG + G E ++
Sbjct: 266 --EDAAGTSGLGELNSR--EQTNQSLRKGKKKKRWHHEEEKMGVLEEGGK-GKEAAGSVR 320
Query: 309 ESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQE 343
T + + AY + ++KK+ +E
Sbjct: 321 -----------TEEVESRAYADPCSRRKKRQQQEE 344
Score = 39.7 bits (91), Expect = 0.013
Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 34/139 (24%)
Query: 258 GLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLH 317
G D PQL + K KKKK+++ +E A E A H
Sbjct: 187 GQDPGAPQLQSESKPPKKKKKKRRQKEEEE-----------------ATASERNDADEKH 229
Query: 318 GETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTA-- 375
P A +N K KKKK HQE + S EG+ G+E G++
Sbjct: 230 ------PEHAEQNIRKSKKKKRRHQEGKV--------SDEREGTTKGNEKEDAAGTSGLG 275
Query: 376 -LKGFKESNSTKKKSKKRK 393
L +++N + +K KK+K
Sbjct: 276 ELNSREQTNQSLRKGKKKK 294
Score = 32.0 bits (71), Expect = 2.7
Identities = 40/219 (18%), Positives = 87/219 (39%), Gaps = 31/219 (14%)
Query: 76 TANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQK 135
TA+ + L K + + LE E+A + + K D + E K
Sbjct: 156 TAHKAARLGITMKAKLARLEAQEQAFLARL---------------KGQDPGAPQLQSESK 200
Query: 136 LPRKPKTDKFQ-------VLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLP 188
P+K K + Q ++ A + H++ +K+KK +R+ + R+
Sbjct: 201 PPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGT- 259
Query: 189 QSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGT 248
++ +++E GE+ + + KKKK+ + E + + EG + AG+
Sbjct: 260 -TKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGS 318
Query: 249 DMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQE 287
E + E+ P ++K +++++++ + E
Sbjct: 319 VRTE-------EVESRAYADPCSRRKKRQQQEEEDLNLE 350
>gi|33356552 G patch domain containing 4 isoform 1 [Homo sapiens]
Length = 375
Score = 46.6 bits (109), Expect = 1e-04
Identities = 49/215 (22%), Positives = 88/215 (40%), Gaps = 36/215 (16%)
Query: 130 MSIEQKLPR-KPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLP 188
++++ KL R + + F K + L S+ + K KK +R+ E A +
Sbjct: 170 ITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERND 229
Query: 189 QSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGT 248
E H P A +N K KKKK ++E + EG+ G E
Sbjct: 230 ADEKH-----------------PEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEK-- 270
Query: 249 DMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQ 308
+++ T GL + + T++ K KKKK+ +H+E + + EG + G E ++
Sbjct: 271 --EDAAGTSGLGELNSR--EQTNQSLRKGKKKKRWHHEEEKMGVLEEGGK-GKEAAGSVR 325
Query: 309 ESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQE 343
T + + AY + ++KK+ +E
Sbjct: 326 -----------TEEVESRAYADPCSRRKKRQQQEE 349
Score = 39.7 bits (91), Expect = 0.013
Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 34/139 (24%)
Query: 258 GLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLH 317
G D PQL + K KKKK+++ +E A E A H
Sbjct: 192 GQDPGAPQLQSESKPPKKKKKKRRQKEEEE-----------------ATASERNDADEKH 234
Query: 318 GETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTA-- 375
P A +N K KKKK HQE + S EG+ G+E G++
Sbjct: 235 ------PEHAEQNIRKSKKKKRRHQEGKV--------SDEREGTTKGNEKEDAAGTSGLG 280
Query: 376 -LKGFKESNSTKKKSKKRK 393
L +++N + +K KK+K
Sbjct: 281 ELNSREQTNQSLRKGKKKK 299
Score = 32.0 bits (71), Expect = 2.7
Identities = 40/219 (18%), Positives = 87/219 (39%), Gaps = 31/219 (14%)
Query: 76 TANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQK 135
TA+ + L K + + LE E+A + + K D + E K
Sbjct: 161 TAHKAARLGITMKAKLARLEAQEQAFLARL---------------KGQDPGAPQLQSESK 205
Query: 136 LPRKPKTDKFQ-------VLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLP 188
P+K K + Q ++ A + H++ +K+KK +R+ + R+
Sbjct: 206 PPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGT- 264
Query: 189 QSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGT 248
++ +++E GE+ + + KKKK+ + E + + EG + AG+
Sbjct: 265 -TKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGS 323
Query: 249 DMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQE 287
E + E+ P ++K +++++++ + E
Sbjct: 324 VRTE-------EVESRAYADPCSRRKKRQQQEEEDLNLE 355
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 46.6 bits (109), Expect = 1e-04
Identities = 84/477 (17%), Positives = 180/477 (37%), Gaps = 47/477 (9%)
Query: 29 PQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKKRKK 88
P++ + + RDSS + RR R++D + SSP++ DE ++R++
Sbjct: 609 PERDNRDQARDSSFERRHGERDRRDNRERDQRP--SSPIRHQGRNDELERD----ERREE 662
Query: 89 RRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVL 148
RR VD+ D+E + + E++ R + +K + L
Sbjct: 663 RRVD--RVDDRRDERARERDRERERDR-------------ERERERERERDREREKEREL 707
Query: 149 AKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEIT 208
+ A + E K R+++ + + E +R RD + E +EE E
Sbjct: 708 ERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERE 767
Query: 209 ELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQ-PTVGLDDETPQLL 267
+ ++ K++ R++E +G RE +++E + P G D+ +
Sbjct: 768 RERERERERARERDKERERQRDWED--KDKGRDDRREKREEIREDRNPRDGHDERKSKKR 825
Query: 268 GPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAP- 326
S ++ K+ ++ A G + Q RP + +
Sbjct: 826 YRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDR 885
Query: 327 --AYKNKSKKKKKKSNHQEFEAVAMPESLESA--------YPEGSQVGSE--VGTVEGST 374
+K + +K ++K + + +E + E + S E S++ ++ +G +
Sbjct: 886 QGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSED 945
Query: 375 ALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVK 434
+ + KKK+K +K K+ DD + N E+T S +G ++G K
Sbjct: 946 RETSDRAHDENKKKAKIQKKPIKKKKE---DDVGIERGNIETT---SEDGQVFSPKKGQK 999
Query: 435 SRPRQKKTQACLASKHVQEAPRLEPANEEHNVE----TAEDSEIRYLSADSGDADDS 487
+ +KK + + + + + ++ T ++ + + +G +DS
Sbjct: 1000 KKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDS 1056
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 46.2 bits (108), Expect = 1e-04
Identities = 64/307 (20%), Positives = 117/307 (38%), Gaps = 38/307 (12%)
Query: 139 KPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESW 198
KP + + + ++S +H R + +H RK+ R+R +S + S
Sbjct: 176 KPGSRRRRSYSRSRSHS--------RSRSRSRHSRKS------RSRSGSSKSSHSKSRSR 221
Query: 199 LSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVG 258
G S +++SKK+K +S ++E + AG+ +++ +
Sbjct: 222 SRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKE---KSRSRSHSAGKSRSKSKDQAEEKIQ 278
Query: 259 LDDET--PQLLGPT-HKKKSKKKKKKKSNHQEFEALAMPEGS-QVGSEVGADMQESRPAV 314
+D P+ P+ HK KSK + + + E E GS G +++SR
Sbjct: 279 NNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEE----KRGSVSRGRSQEKSLRQSRSRS 334
Query: 315 GLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPES-LESAYPEGSQVGSEVGTVEGS 373
G + K+K K+K +K + +E + + S E + GS+ S+ G+
Sbjct: 335 RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS---- 390
Query: 374 TALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGV 433
S KK+ R + VS + S++S+ E G E
Sbjct: 391 --------SKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRS 442
Query: 434 KSRPRQK 440
+SR K
Sbjct: 443 RSRSNSK 449
Score = 38.1 bits (87), Expect = 0.037
Identities = 59/291 (20%), Positives = 108/291 (37%), Gaps = 30/291 (10%)
Query: 149 AKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEIT 208
++S + S+ +++K++ ++ + S A + +S+ EE + G+
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 209 ELPASAHKNKSKKKKKKSSNREYETLAMPEGS-QAGREAGTDMQESQPTVGLDDETPQLL 267
S HK+KSK + + R E GS GR +++S+ +
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEE---KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS 344
Query: 268 GPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPA 327
K K K+K +K+S E S+ S + + SR AG
Sbjct: 345 RSRSKSKDKRKGRKRSR----------EESRSRSRSRSKSERSRKRGSKRDSKAG----- 389
Query: 328 YKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKK 387
S KKKKK + ++ + S+ E SE EG +G E+ T +
Sbjct: 390 ----SSKKKKKEDTDRSQSRSPSRSVSK---EREHAKSESSQREG----RGESENAGTNQ 438
Query: 388 KSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPR 438
+++ R ++ K + SK++ T S + +SR R
Sbjct: 439 ETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 45.8 bits (107), Expect = 2e-04
Identities = 68/310 (21%), Positives = 118/310 (38%), Gaps = 45/310 (14%)
Query: 16 DKKKKKCSIHKERP--------QKHSHEIFRDSS---LVNEQSQITRRKKRKKDFQHLIS 64
DK K+ + KER +K S + FR+ L E+ I K +F L
Sbjct: 710 DKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKD--SEFTSLGM 767
Query: 65 SPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVD 124
S +++S I ++K++K + E E+ + +K+ K F K+
Sbjct: 768 SAIEES-IGLHLVEKEIDIEKQEKHIKESKEKPEKRSQ---IKEKDIEKMERKTFEKEKK 823
Query: 125 VVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKV--------------REKKNKK 170
+ S + KL DK + K ++H +E H + REK +K
Sbjct: 824 IKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREK 883
Query: 171 HQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNRE 230
RK + ++ R E H E E ++ +K K ++ KK +R+
Sbjct: 884 MDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRD 943
Query: 231 YETLAMPEGSQAGREA------GTDMQESQPTVGLDDETPQ--LLGPTHKKKSKKKK--- 279
E++ + E G Q +P + L ++T L P K+K KK K
Sbjct: 944 KESINITNSKHIQEEKKSSIVDGNKAQHEKP-LSLKEKTKDEPLKTPDGKEKDKKDKDID 1002
Query: 280 --KKKSNHQE 287
K++ H++
Sbjct: 1003 RYKERDKHKD 1012
Score = 37.0 bits (84), Expect = 0.083
Identities = 99/511 (19%), Positives = 183/511 (35%), Gaps = 73/511 (14%)
Query: 12 TPVSDKKKKKCSIHKERPQKHSHEIFR----DSSLVNEQSQIT-----RRKKRKKDFQHL 62
TP+ + K C ++ R +S + E S + + K +KDF HL
Sbjct: 533 TPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDF-HL 591
Query: 63 ISSPLKKSRICDET-----ANATSTLKKR-------KKRRYSALEVDEEAGVTVVLVDKE 110
++I DE N+ TLKK KK + E ++E + +KE
Sbjct: 592 EFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKE 651
Query: 111 NINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKK 170
K K++ V+ E K+D+ + L + H+S L K + +KN K
Sbjct: 652 KYKT--KDSAKELQR-SVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIK 708
Query: 171 HQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNRE 230
+ + R+ + + ++ES + +++K K E
Sbjct: 709 DDKSTKEKHVSKERNFKEERDKIKKES------------------EKSFREEKIKDLKEE 750
Query: 231 YETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEA 290
E + + S+ + ++ES ++ E H K+SK+K +K+S +E +
Sbjct: 751 RENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDI 810
Query: 291 LAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMP 350
M E +E + E + +K K+K K +H
Sbjct: 811 EKM--------ERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHT------- 855
Query: 351 ESLESAYPEGSQVGSEVG---TVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDF 407
E + EG + + T + + + + +K K+R L K + +
Sbjct: 856 ---EKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLM-EKK 911
Query: 408 SVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPR---LEPANEEH 464
+ S NSE + + + E K + R K++ SKH+QE + ++ +H
Sbjct: 912 NKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQH 971
Query: 465 N-----VETAEDSEIRYLSADSGDADDSDAD 490
E +D ++ D D D D
Sbjct: 972 EKPLSLKEKTKDEPLKTPDGKEKDKKDKDID 1002
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 45.8 bits (107), Expect = 2e-04
Identities = 68/310 (21%), Positives = 118/310 (38%), Gaps = 45/310 (14%)
Query: 16 DKKKKKCSIHKERP--------QKHSHEIFRDSS---LVNEQSQITRRKKRKKDFQHLIS 64
DK K+ + KER +K S + FR+ L E+ I K +F L
Sbjct: 733 DKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKD--SEFTSLGM 790
Query: 65 SPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVD 124
S +++S I ++K++K + E E+ + +K+ K F K+
Sbjct: 791 SAIEES-IGLHLVEKEIDIEKQEKHIKESKEKPEKRSQ---IKEKDIEKMERKTFEKEKK 846
Query: 125 VVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKV--------------REKKNKK 170
+ S + KL DK + K ++H +E H + REK +K
Sbjct: 847 IKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREK 906
Query: 171 HQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNRE 230
RK + ++ R E H E E ++ +K K ++ KK +R+
Sbjct: 907 MDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRD 966
Query: 231 YETLAMPEGSQAGREA------GTDMQESQPTVGLDDETPQ--LLGPTHKKKSKKKK--- 279
E++ + E G Q +P + L ++T L P K+K KK K
Sbjct: 967 KESINITNSKHIQEEKKSSIVDGNKAQHEKP-LSLKEKTKDEPLKTPDGKEKDKKDKDID 1025
Query: 280 --KKKSNHQE 287
K++ H++
Sbjct: 1026 RYKERDKHKD 1035
Score = 37.0 bits (84), Expect = 0.083
Identities = 99/511 (19%), Positives = 183/511 (35%), Gaps = 73/511 (14%)
Query: 12 TPVSDKKKKKCSIHKERPQKHSHEIFR----DSSLVNEQSQIT-----RRKKRKKDFQHL 62
TP+ + K C ++ R +S + E S + + K +KDF HL
Sbjct: 556 TPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDF-HL 614
Query: 63 ISSPLKKSRICDET-----ANATSTLKKR-------KKRRYSALEVDEEAGVTVVLVDKE 110
++I DE N+ TLKK KK + E ++E + +KE
Sbjct: 615 EFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKE 674
Query: 111 NINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKK 170
K K++ V+ E K+D+ + L + H+S L K + +KN K
Sbjct: 675 KYKT--KDSAKELQR-SVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIK 731
Query: 171 HQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNRE 230
+ + R+ + + ++ES + +++K K E
Sbjct: 732 DDKSTKEKHVSKERNFKEERDKIKKES------------------EKSFREEKIKDLKEE 773
Query: 231 YETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEA 290
E + + S+ + ++ES ++ E H K+SK+K +K+S +E +
Sbjct: 774 RENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDI 833
Query: 291 LAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMP 350
M E +E + E + +K K+K K +H
Sbjct: 834 EKM--------ERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHT------- 878
Query: 351 ESLESAYPEGSQVGSEVG---TVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDF 407
E + EG + + T + + + + +K K+R L K + +
Sbjct: 879 ---EKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLM-EKK 934
Query: 408 SVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPR---LEPANEEH 464
+ S NSE + + + E K + R K++ SKH+QE + ++ +H
Sbjct: 935 NKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQH 994
Query: 465 N-----VETAEDSEIRYLSADSGDADDSDAD 490
E +D ++ D D D D
Sbjct: 995 EKPLSLKEKTKDEPLKTPDGKEKDKKDKDID 1025
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 45.4 bits (106), Expect = 2e-04
Identities = 63/264 (23%), Positives = 106/264 (40%), Gaps = 42/264 (15%)
Query: 202 GPGGEITE----LPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTV 257
GP ++ + LP+ + + KKKKKK+++ E + G G D QE
Sbjct: 575 GPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKD-DFPGGVDNQELNRN- 632
Query: 258 GLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLH 317
L G +KK KK+ K K + +E P+ + E P +
Sbjct: 633 -------SLDGSQEEKKKKKRSKAKKDPKE------PKEPKEKKEPKEPKTPKAPKI--P 677
Query: 318 GETAGIPAPAYKNKSKKKKKKSNHQ-EFEAVAMPESLESAYPEGSQVGSEVGTVEGSTAL 376
E A K K KK SN + + EA A+ + + +G GSE ++ +
Sbjct: 678 KEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVN----KGKTEGSENSDLDKTPPP 733
Query: 377 KGFKESNSTKKKSKKRKLTSVKRARVSGD-DFSV---------------PSKNSESTLFD 420
E + K+R VKR R + D +F + PS S+S +
Sbjct: 734 SPPPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQE 793
Query: 421 SVEGDGAMMEEGVKSRPRQKKTQA 444
SV+ +G ++E+ + SR +K+ ++
Sbjct: 794 SVDAEGPVVEKIMSSRSVKKQKES 817
Score = 41.6 bits (96), Expect = 0.003
Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 9/165 (5%)
Query: 133 EQKLPRKPKTDKFQVLAKSHAHKSEALHS----KVREKKNKKHQRKAASWESQRARDTLP 188
E+K P++PKT K + K K + ++ NKK +A++ + + +
Sbjct: 661 EKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTE 720
Query: 189 QSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPE----GSQAGR 244
SE+ + P E E P + S++ K+K + E E AGR
Sbjct: 721 GSENSDLDKTPPPSPPPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGR 780
Query: 245 EAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFE 289
++ ++ +S+ +D E P ++ +S KK+K+ E E
Sbjct: 781 DSPSNTSQSEQQESVDAEGP-VVEKIMSSRSVKKQKESGEEVEIE 824
Score = 40.0 bits (92), Expect = 0.010
Identities = 63/315 (20%), Positives = 120/315 (38%), Gaps = 49/315 (15%)
Query: 260 DDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGE 319
DD P + ++ +KKKKKK+NH E + G G D QE L+
Sbjct: 584 DDYLPSI----EQQPQQKKKKKKNNHIVAEDPSKGFGKD-DFPGGVDNQE------LNRN 632
Query: 320 TAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGF 379
+ K K + K KK + E E E P+ ++ E + TA
Sbjct: 633 SLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKP 692
Query: 380 KESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQ 439
K S + K + +++K+ G ++ SE++ D EE ++
Sbjct: 693 KSSKKSSNKKPDSEASALKKKVNKG-----KTEGSENSDLDKTPPPSPPPEEDEDPGVQK 747
Query: 440 KKTQACLASKHVQEAPRLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSAVKQLQ 499
+++ + K E + ++EE AD DA D+ ++ + Q
Sbjct: 748 RRSSRQVKRKRYTEDLEFKISDEE---------------ADDADAAGRDSPSNTSQSEQQ 792
Query: 500 EFI----PNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFS-----------VKEN 544
E + P ++ +S R + E +E + + +K+ FS ++++
Sbjct: 793 ESVDAEGPVVEKIMSS---RSVKKQKESGEEVEIEEFYVKYKNFSYLHCQWASIEDLEKD 849
Query: 545 KQLEKNVEDFLALTG 559
K++++ ++ F A G
Sbjct: 850 KRIQQKIKRFKAKQG 864
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 45.4 bits (106), Expect = 2e-04
Identities = 98/470 (20%), Positives = 168/470 (35%), Gaps = 86/470 (18%)
Query: 14 VSDKKKKKCSIHKERPQKHSHEI-----FRDSSLVNEQSQITRRKKR---KKDFQHLISS 65
+ ++K K+ + + P K SHE + SS N +SQ ++ + +KD + +S
Sbjct: 147 IVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNS 206
Query: 66 PLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLV------DKENIN------ 113
+ N LK+ K E+ E + V + D E+IN
Sbjct: 207 KKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLR 266
Query: 114 --------------------NTPKHFRKDVDVVCVDMSIEQKLPRKPKTD------KFQV 147
+T K+ +K D D +K +K K + K V
Sbjct: 267 NYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDV 326
Query: 148 LAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEI 207
+ + +E+ SK K KK ++K + + +DT ES ES + +
Sbjct: 327 KKDTESTDAESGDSKDERKDTKKDKKKLK--KDDKKKDTKKYPESTDTESGDAKDARNDS 384
Query: 208 TELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQP----TVGLDDET 263
L A KN KKK K ++ + E ++ ++ D ++S+ +V D+E+
Sbjct: 385 RNLK-KASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEES 443
Query: 264 P----------------QLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADM 307
+ G KK KKK K N + E + E+ D
Sbjct: 444 TDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTE-------MESDLELKKDK 496
Query: 308 QESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEV 367
+ S+ G + K +K +S EF+ + S +GS SE
Sbjct: 497 KHSKEKKGSKKDI---------KKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEE 547
Query: 368 GTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSEST 417
+ A K ES+ T SK L S + R+S + K +++
Sbjct: 548 SLYKPG-AKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKAS 596
>gi|111607441 hypothetical protein LOC400506 [Homo sapiens]
Length = 458
Score = 45.1 bits (105), Expect = 3e-04
Identities = 69/247 (27%), Positives = 96/247 (38%), Gaps = 43/247 (17%)
Query: 117 KHFRKDVDVVCVD-MSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKA 175
K +K V +C + + E LP + +T+K L K E L EKKNKK
Sbjct: 68 KKKKKGVSTLCEEHVEPETTLPAR-RTEKSPSLRKQVFGHLEFLSG---EKKNKKS---- 119
Query: 176 ASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLA 235
P + SH S P E K KK+KK + + ++
Sbjct: 120 ------------PLAMSHASGVKTSPDPRQGEEETRVGKKLKKHKKEKKGAQDPTAFSVQ 167
Query: 236 MPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKK-----KKKKSNHQEFEA 290
P +A REA D+ ++ +VG DE LG K+KS ++ KKKK HQE +A
Sbjct: 168 DPWFCEA-REA-RDVGDTC-SVGKKDEEQAALGQKRKRKSPREHNGKVKKKKKIHQEGDA 224
Query: 291 LAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAY-------KNKSKKKKKKSNHQE 343
L G + ES P G + + AP Y K +KKK K E
Sbjct: 225 LP-------GHSKPSRSMESSPRKGSKKKPVKVEAPEYIPISDDPKASAKKKMKSKKKVE 277
Query: 344 FEAVAMP 350
+ P
Sbjct: 278 QPVIEEP 284
Score = 35.0 bits (79), Expect = 0.32
Identities = 65/331 (19%), Positives = 117/331 (35%), Gaps = 55/331 (16%)
Query: 17 KKKKKCSIHKERPQKHS----HEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKK--- 69
+KKKK + KE ++S + F D S + S + L+ KK
Sbjct: 14 EKKKKKKVVKEPETRYSVLNNDDYFADVSPLRATSPSKSVAHGQAPEMPLVKKKKKKKKG 73
Query: 70 -SRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCV 128
S +C+E +TL R+ + +L + + +K+N +K +
Sbjct: 74 VSTLCEEHVEPETTLPARRTEKSPSLRKQVFGHLEFLSGEKKN--------KKSPLAMSH 125
Query: 129 DMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLP 188
++ + ++ +V K HK E ++ + + + E++ DT
Sbjct: 126 ASGVKTSPDPRQGEEETRVGKKLKKHKKEKKGAQDPTAFSVQDPWFCEAREARDVGDTCS 185
Query: 189 QSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGT 248
+ +E++ L G + H K KKKKK + A+P S+ R +
Sbjct: 186 VGKKDEEQAAL----GQKRKRKSPREHNGKVKKKKKIHQEGD----ALPGHSKPSRSMES 237
Query: 249 DMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQ 308
++ + E P+ + + K+ KKK KS +
Sbjct: 238 SPRKGSKKKPVKVEAPEYIPISDDPKASAKKKMKSKKKV--------------------- 276
Query: 309 ESRPAVGLHGETAGIPAPAYKNKSKKKKKKS 339
E I PA K K KKK+K+S
Sbjct: 277 ----------EQPVIEEPALKRKKKKKRKES 297
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 45.1 bits (105), Expect = 3e-04
Identities = 89/374 (23%), Positives = 131/374 (35%), Gaps = 51/374 (13%)
Query: 154 HKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQ-SESHQEESWLSVGP--------- 203
H A SK K KAA+ SQ A T+ + SE +E S
Sbjct: 427 HPKNAPESKKGSSPKPKSCIKAAA--SQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKK 484
Query: 204 --GGEITELPASAHKNKSKKKKKKSSNREYET-LAMPEGSQAGREAGTDMQESQPTVGLD 260
GG++++ +H K + + SN ET LA P G ++ P + D
Sbjct: 485 ALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKD 544
Query: 261 DET----PQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGL 316
+ T P L K + + +F+ + G+E D+ S L
Sbjct: 545 ESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKD-HL 603
Query: 317 HGETAGIPAPAYKNKSKK----KKKKSNHQEFEAVAMPES---LESAYPEGSQVGSEVGT 369
G G P NKSK+ K +S+ +A A + L P GS GSE
Sbjct: 604 QGLDPGEP-----NKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSH-GSETED 657
Query: 370 VEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMM 429
S K + S + K KK+ S K R D S +ES
Sbjct: 658 TGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESG------------ 705
Query: 430 EEGVKSRPRQKKTQACLASKHVQEAPRLE------PANEEHNVETAEDSEIRYLSADSGD 483
E+ K + R++K A + P+ E PA +DS+ R L A+ G
Sbjct: 706 EKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGS 765
Query: 484 ADDSDADLGSAVKQ 497
+ D G + Q
Sbjct: 766 SGKKDEGGGGSSSQ 779
Score = 41.6 bits (96), Expect = 0.003
Identities = 52/286 (18%), Positives = 113/286 (39%), Gaps = 31/286 (10%)
Query: 150 KSHAHKSEALHSKVREKKNKKHQRK---------AASWESQRARDTLPQSESHQEESWLS 200
KSH HK + H KK+ KH+RK + + ++++ + + S +
Sbjct: 671 KSHRHKKKKKH-----KKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPA 725
Query: 201 VGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLD 260
G E P S +++++ + + +L EGS ++ G SQ G
Sbjct: 726 DSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRK 785
Query: 261 DETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGET 320
+ +L + ++++ K+ +S+H+ + + S S+ + E
Sbjct: 786 HK-GELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEED 844
Query: 321 AGIPAPAYKNKSKKK--KKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKG 378
+G +++S ++ +S+ + + + + S +S Y + + + +
Sbjct: 845 SGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRH 904
Query: 379 FKESN--------STKKKSKKRKLTSVKRARVSGDDFSVPSKNSES 416
K S+ S+K +SK+ K +S S DD+S+ S S
Sbjct: 905 SKRSHDSDDSDYASSKHRSKRHKYSS------SDDDYSLSCSQSRS 944
Score = 35.4 bits (80), Expect = 0.24
Identities = 49/278 (17%), Positives = 106/278 (38%), Gaps = 19/278 (6%)
Query: 209 ELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQE-----------SQPTV 257
E +H++K KKK KKSS + + A E + E+G ++ S P
Sbjct: 667 ERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPAD 726
Query: 258 GLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLH 317
P+ G +++++ + + Q +L EGS + G S+ G
Sbjct: 727 SERGPKPEPPGSGSPAPPRRRRRAQDDSQR-RSLPAEEGSSGKKDEGGGGSSSQDHGGRK 785
Query: 318 GETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALK 377
+ P+ + K+ +S+H+ + +S +++ Q + E
Sbjct: 786 HKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDS 845
Query: 378 GFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRP 437
G + S S + R+ +S + +R S S S + D + + +SR
Sbjct: 846 GSEHSRSRSRSG--RRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRR 903
Query: 438 RQKKTQAC-----LASKHVQEAPRLEPANEEHNVETAE 470
K++ +SKH + + +++++++ ++
Sbjct: 904 HSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQ 941
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 44.7 bits (104), Expect = 4e-04
Identities = 40/158 (25%), Positives = 71/158 (44%), Gaps = 7/158 (4%)
Query: 133 EQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSES 192
E+K RK K+ + + S S + S+ EKK K ++K + + ++ + +SES
Sbjct: 92 ERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESES 151
Query: 193 HQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQE 252
+ES + TE +S KK+K S + + L+ S++ E ++
Sbjct: 152 ESKESVKKKKKSKDETEKEKDV---RSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKK 208
Query: 253 S---QPTVGLDDETPQLLGPTHKKKSKKKKKKK-SNHQ 286
+ ++ + HKK SKKKKKK S+H+
Sbjct: 209 KRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHK 246
Score = 40.0 bits (92), Expect = 0.010
Identities = 56/252 (22%), Positives = 97/252 (38%), Gaps = 66/252 (26%)
Query: 164 REKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKK 223
++ +NKK KA + ++ + + E LS G E +S+ K + KKK+
Sbjct: 46 KQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLS---GNE-----SSSKKRERKKKR 97
Query: 224 KKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKS 283
KK S R + + + S + ++ +DE KK+ K++KKKK+
Sbjct: 98 KKKSCRSSSSSSSSDSSSSSSDS-------------EDE--------EKKQGKRRKKKKN 136
Query: 284 NHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQE 343
+ + E ES+ +V K KKK K +E
Sbjct: 137 RSYKSSQSSTHESES----------ESKESV----------------KKKKKSKDETEKE 170
Query: 344 FEAVAMPESLESAYPE----GSQVGSEVGTVEGSTALKGFK-------ESNSTKKKSKKR 392
+ ++ + + +YP+ S+ SE E A K + + KKK K+
Sbjct: 171 KDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQH 230
Query: 393 KLTSVKRARVSG 404
K S K+ + SG
Sbjct: 231 KKHSKKKKKKSG 242
Score = 33.9 bits (76), Expect = 0.70
Identities = 39/173 (22%), Positives = 71/173 (41%), Gaps = 24/173 (13%)
Query: 17 KKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDET 76
KK+KK S S S +E+ + +R+K+KK+ + S +S +
Sbjct: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSS----QSSTHESE 150
Query: 77 ANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKL 136
+ + ++KK+KK S E ++E D +++ K D + + S E
Sbjct: 151 SESKESVKKKKK---SKDETEKEK-------DVRSLSKKRKKSYPDDKPLSSESSSESDY 200
Query: 137 PRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKH-----QRKAASWESQRAR 184
+ Q K + E KV++KK K+H ++K S S ++R
Sbjct: 201 -----EEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
Score = 31.2 bits (69), Expect = 4.6
Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 6 SRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISS 65
S E V KKK K KE+ + + + S + ++ + D++ + +
Sbjct: 149 SESESKESVKKKKKSKDETEKEKDVRSLSKKRKKS--YPDDKPLSSESSSESDYEEDVQA 206
Query: 66 PLKKSRICDETANATSTLKKRKKRRY 91
KK R C+E A +KK+KK+++
Sbjct: 207 --KKKRRCEEREQAKEKVKKKKKKQH 230
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 43.9 bits (102), Expect = 7e-04
Identities = 96/471 (20%), Positives = 173/471 (36%), Gaps = 57/471 (12%)
Query: 1 MEGESSRFEIHTPVSDKKKKKCSIHKER-PQKHSHE----IFRDSSLVNEQSQITRRKKR 55
+EG+ + + TP + +++K + +E +K S E + D L E+S+I + K
Sbjct: 1978 VEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLE 2037
Query: 56 KKDFQHL-ISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINN 114
Q + + K ++ + +L K + L+ ++ + +E I
Sbjct: 2038 FTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKM 2097
Query: 115 TPKHFRKDVDVVCVDMSIEQ-KLPRKP-----KTDKFQVLAKSHAHKSEALHSKVREKKN 168
T ++ + V +SIEQ KL K K + K A K L +K+R N
Sbjct: 2098 TK--MKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMIN 2155
Query: 169 KKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSN 228
K + K ES+ AR +EE + E +P + + +K+ K+
Sbjct: 2156 K--EEKMTEEESKLARKHSEVILDDEEEGGIE-----EEEVIPFLKRRWRKRKEAKR--- 2205
Query: 229 REYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKS----KKKKKKKSN 284
G + + + + E + +E LL K++S +++++++
Sbjct: 2206 ----------GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEE 2255
Query: 285 HQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEF 344
+E E + E + E G + Q + K K KK+KKK QE
Sbjct: 2256 EREEEEVREEEEERKEEEEGEEKQVEKEE-------------EEKKKKKKEKKKEEVQEK 2302
Query: 345 EAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSG 404
E V + + E + E E + + KK K+ KL +R + G
Sbjct: 2303 EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRG 2362
Query: 405 DDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAP 455
+ + S L G G + GV P +K L K P
Sbjct: 2363 RERVL------SILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVP 2407
Score = 36.6 bits (83), Expect = 0.11
Identities = 54/259 (20%), Positives = 103/259 (39%), Gaps = 22/259 (8%)
Query: 221 KKKKKSSNREYETLAMPEGS---QAGREAGTDMQESQPTVGLD-DETPQLLGPTHKKKSK 276
+K K+ E+E + E QAG + + + Q L +E Q+ KSK
Sbjct: 1475 RKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSK 1534
Query: 277 KKKKKKSNHQEFEALAMPEGSQVGSEVGAD---MQESRPAVGLHGETAGIPAPAYKNKSK 333
+++ K E EG + +V + +QE +H + A + + K
Sbjct: 1535 EQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERK 1594
Query: 334 --KKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALK-------GFKESNS 384
++++K +E + L AY + +Q E+ EG A K G K S
Sbjct: 1595 LAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQE 1654
Query: 385 TKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQA 444
+K ++KRK + K +V+ ++ + K + ++ + + V+ P++++
Sbjct: 1655 AEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNI------LAQKVEELPQREQNLD 1708
Query: 445 CLASKHVQEAPRLEPANEE 463
+ QE LE EE
Sbjct: 1709 WQEKELAQELEELEWDMEE 1727
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 43.9 bits (102), Expect = 7e-04
Identities = 77/370 (20%), Positives = 130/370 (35%), Gaps = 70/370 (18%)
Query: 47 SQITRRKKRKKDFQHLISSPL--------KKSRICDETANATSTLKKRKKRRY------S 92
S+++++ ++ F L P K S+I D T + + R RR S
Sbjct: 21 SELSKKSWNQQHFALLFPKPQRPGTKRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRS 80
Query: 93 ALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVL--AK 150
+ + E +V L + + D + E K +K TD L K
Sbjct: 81 LMRISERP--SVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGK 138
Query: 151 SHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITEL 210
+ K + + EK + K K ++++ +D+ +SE + GG
Sbjct: 139 KDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEK---------GGA---- 185
Query: 211 PASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPT 270
K KK KK SN+ ++ EG + G E +
Sbjct: 186 ------KKDNKKDKKDSNKGKDSATESEGEKGGTEKDS---------------------- 217
Query: 271 HKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADM-QESRPAVGLHGETAGIPAPAYK 329
KK K KK K + E +A+ E + A+ ES+ A E K
Sbjct: 218 -KKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIK-------K 269
Query: 330 NKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKS 389
K KKK S + + ES + A + +V + E + + K K+ + KK +
Sbjct: 270 GKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKK--NAKKDA 327
Query: 390 KKRKLTSVKR 399
KK + K+
Sbjct: 328 KKDAKKNAKK 337
Score = 31.2 bits (69), Expect = 4.6
Identities = 65/288 (22%), Positives = 106/288 (36%), Gaps = 61/288 (21%)
Query: 247 GTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKK-KKSNHQEFEALAMPEGSQVGSEVGA 305
G D + T + E Q KK SKK K +K ++ +A + + +E G
Sbjct: 118 GEDKTTQKDTTDSESELKQ-----GKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGK 172
Query: 306 DMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGS 365
D A E G K +KK KK SN + A EG + G+
Sbjct: 173 DS-----ATESEDEKGGA-----KKDNKKDKKDSNKGKDSATES---------EGEKGGT 213
Query: 366 EVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGD 425
E K+S KK SKK K ++++ V D+ K E D+ +GD
Sbjct: 214 E-------------KDSKKGKKDSKKGKDSAIELQAVKADE-----KKDEDGKKDANKGD 255
Query: 426 GAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHNV--ETAEDSEIRYLSADSGD 483
+S+ +K + K ++ P ++ + +V E+ +D+ D
Sbjct: 256 --------ESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKD 307
Query: 484 ADDSDADLGSAVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQG 531
+ AD K+ N K A K+ + D + K+ K +G
Sbjct: 308 TEKESADSKKDAKK------NAKKDAKKDAKKNAKKDEK--KDAKKKG 347
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 11/239 (4%)
Query: 185 DTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEG-SQAG 243
D +++ Q LS GG+ E + KS+K KK + N + TLA+ +Q
Sbjct: 1166 DGKQEAKPQQAAGMLSPKTGGK--EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCL 1223
Query: 244 REAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEV 303
+ E+Q + +LL KK K+ E + G Q +
Sbjct: 1224 LGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKL-SGDQPAART 1282
Query: 304 GADMQESRPAVGLHGETAGIP---APAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEG 360
++ + G GE + P + K K+K+ K + +E + S +
Sbjct: 1283 PRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPE 1342
Query: 361 SQVGSEVGTVEG----STALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSE 415
++ +GTVEG + K K+ + +KK K++K K + S D PS+ +
Sbjct: 1343 EELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1401
Score = 39.3 bits (90), Expect = 0.017
Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 20/303 (6%)
Query: 172 QRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNR-- 229
Q KA+ SQ + P ES ++ + + P G+ A A K ++ + SS
Sbjct: 284 QAKASGKTSQVGAASAPAKESPRKGA--APAPPGKTGPAVAKAQAGKREEDSQSSSEESD 341
Query: 230 ---EYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGP------THKKKSKKKKK 280
E A P G A + + P G P+ GP K++ +
Sbjct: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 401
Query: 281 KKSNHQEFEALAMPEGSQVGSEVGADMQ---ESRPAVGLHGETAGIPAPAYKNKSKKKKK 337
+ + + EALA +QV +G Q S +G G+ AG P + +
Sbjct: 402 SEESDSDREALAAMNAAQV-KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 460
Query: 338 KSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSV 397
+E + ES +S+ E + L+ S+ K +K +V
Sbjct: 461 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 520
Query: 398 K-RARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPR 456
+ +A D+ ++S+S DS E AM K + +T+AC + + +
Sbjct: 521 QVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAK 578
Query: 457 LEP 459
+ P
Sbjct: 579 VAP 581
Score = 39.3 bits (90), Expect = 0.017
Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 28/194 (14%)
Query: 95 EVDEEAGVTVVLVD------KENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVL 148
E +A V VL + K+ ++ T + RK + +S +Q R P++ K + L
Sbjct: 1232 EAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKL 1291
Query: 149 AKSHAHKSEALHSKVREKKNKKHQRKAASWE--SQRARDTL-PQSESHQEESWLSVGPGG 205
++ K K +R AS + ++ + +L Q + E L G G
Sbjct: 1292 GAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMG- 1350
Query: 206 EITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQ 265
T KSKK+KKKS R+ + E + ++A T ES
Sbjct: 1351 --TVEGGDQSNPKSKKEKKKSDKRKKDK-EKKEKKKKAKKASTKDSES------------ 1395
Query: 266 LLGPTHKKKSKKKK 279
P+ KKK KKKK
Sbjct: 1396 ---PSQKKKKKKKK 1406
Score = 35.8 bits (81), Expect = 0.19
Identities = 41/192 (21%), Positives = 79/192 (41%), Gaps = 16/192 (8%)
Query: 115 TPKHFRK--------DVDVVCVDMSIEQKLPRKP-KTDKFQVLAKSHAHKSEALHSKVRE 165
TP+ RK + + +I Q L +P ++ QV A +E L + ++
Sbjct: 1194 TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKK 1253
Query: 166 KKNKKHQRKAASWESQRARDTLPQSESH----QEESWLSVGPGGEITELP---ASAHKNK 218
+ + WES++ + + Q + +++ L G GGE + P ++ K K
Sbjct: 1254 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1313
Query: 219 SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKK 278
+K+ K +E + A E ++Q+ TV D++ KK K+K
Sbjct: 1314 AKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRK 1373
Query: 279 KKKKSNHQEFEA 290
K K+ ++ +A
Sbjct: 1374 KDKEKKEKKKKA 1385
Score = 31.2 bits (69), Expect = 4.6
Identities = 62/305 (20%), Positives = 104/305 (34%), Gaps = 48/305 (15%)
Query: 203 PGGEITELPASAHKNK-------SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQP 255
P G++ SA K S ++ SS+ E T P A ++ ++ +++P
Sbjct: 448 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP----AQEKSLGNILQAKP 503
Query: 256 TVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVG 315
T PQ GP + +K S E S+ S+ AD +E+ A+
Sbjct: 504 TSSPAKGPPQKAGPVAVQVKAEKPMDNS-----------ESSEESSD-SADSEEAPAAM- 550
Query: 316 LHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTA 375
TA PA K K K + A P + + P + G+ S A
Sbjct: 551 ----TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR--KAGTATSPAGSSPA 604
Query: 376 LKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKS 435
+ G + + S + E T G + +G++
Sbjct: 605 VAGGTQRPAEDSSSSEES-----------------DSEEEKTGLAVTVGQAKSVGKGLQV 647
Query: 436 RPRQKKTQACLASKHVQEAP-RLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSA 494
+ + L P + P + E EDSE +DS +A S A + ++
Sbjct: 648 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 707
Query: 495 VKQLQ 499
VK+ Q
Sbjct: 708 VKKTQ 712
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 11/239 (4%)
Query: 185 DTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEG-SQAG 243
D +++ Q LS GG+ E + KS+K KK + N + TLA+ +Q
Sbjct: 1205 DGKQEAKPQQAAGMLSPKTGGK--EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCL 1262
Query: 244 REAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEV 303
+ E+Q + +LL KK K+ E + G Q +
Sbjct: 1263 LGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKL-SGDQPAART 1321
Query: 304 GADMQESRPAVGLHGETAGIP---APAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEG 360
++ + G GE + P + K K+K+ K + +E + S +
Sbjct: 1322 PRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPE 1381
Query: 361 SQVGSEVGTVEG----STALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSE 415
++ +GTVEG + K K+ + +KK K++K K + S D PS+ +
Sbjct: 1382 EELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1440
Score = 39.3 bits (90), Expect = 0.017
Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 20/303 (6%)
Query: 172 QRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNR-- 229
Q KA+ SQ + P ES ++ + + P G+ A A K ++ + SS
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGA--APAPPGKTGPAVAKAQAGKREEDSQSSSEESD 418
Query: 230 ---EYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGP------THKKKSKKKKK 280
E A P G A + + P G P+ GP K++ +
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 478
Query: 281 KKSNHQEFEALAMPEGSQVGSEVGADMQ---ESRPAVGLHGETAGIPAPAYKNKSKKKKK 337
+ + + EALA +QV +G Q S +G G+ AG P + +
Sbjct: 479 SEESDSDREALAAMNAAQV-KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
Query: 338 KSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSV 397
+E + ES +S+ E + L+ S+ K +K +V
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 597
Query: 398 K-RARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPR 456
+ +A D+ ++S+S DS E AM K + +T+AC + + +
Sbjct: 598 QVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAK 655
Query: 457 LEP 459
+ P
Sbjct: 656 VAP 658
Score = 39.3 bits (90), Expect = 0.017
Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 28/194 (14%)
Query: 95 EVDEEAGVTVVLVD------KENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVL 148
E +A V VL + K+ ++ T + RK + +S +Q R P++ K + L
Sbjct: 1271 EAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKL 1330
Query: 149 AKSHAHKSEALHSKVREKKNKKHQRKAASWE--SQRARDTL-PQSESHQEESWLSVGPGG 205
++ K K +R AS + ++ + +L Q + E L G G
Sbjct: 1331 GAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMG- 1389
Query: 206 EITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQ 265
T KSKK+KKKS R+ + E + ++A T ES
Sbjct: 1390 --TVEGGDQSNPKSKKEKKKSDKRKKDK-EKKEKKKKAKKASTKDSES------------ 1434
Query: 266 LLGPTHKKKSKKKK 279
P+ KKK KKKK
Sbjct: 1435 ---PSQKKKKKKKK 1445
Score = 35.8 bits (81), Expect = 0.19
Identities = 41/192 (21%), Positives = 79/192 (41%), Gaps = 16/192 (8%)
Query: 115 TPKHFRK--------DVDVVCVDMSIEQKLPRKP-KTDKFQVLAKSHAHKSEALHSKVRE 165
TP+ RK + + +I Q L +P ++ QV A +E L + ++
Sbjct: 1233 TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKK 1292
Query: 166 KKNKKHQRKAASWESQRARDTLPQSESH----QEESWLSVGPGGEITELP---ASAHKNK 218
+ + WES++ + + Q + +++ L G GGE + P ++ K K
Sbjct: 1293 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1352
Query: 219 SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKK 278
+K+ K +E + A E ++Q+ TV D++ KK K+K
Sbjct: 1353 AKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRK 1412
Query: 279 KKKKSNHQEFEA 290
K K+ ++ +A
Sbjct: 1413 KDKEKKEKKKKA 1424
Score = 31.2 bits (69), Expect = 4.6
Identities = 62/305 (20%), Positives = 104/305 (34%), Gaps = 48/305 (15%)
Query: 203 PGGEITELPASAHKNK-------SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQP 255
P G++ SA K S ++ SS+ E T P A ++ ++ +++P
Sbjct: 525 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP----AQEKSLGNILQAKP 580
Query: 256 TVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVG 315
T PQ GP + +K S E S+ S+ AD +E+ A+
Sbjct: 581 TSSPAKGPPQKAGPVAVQVKAEKPMDNS-----------ESSEESSD-SADSEEAPAAM- 627
Query: 316 LHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTA 375
TA PA K K K + A P + + P + G+ S A
Sbjct: 628 ----TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR--KAGTATSPAGSSPA 681
Query: 376 LKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKS 435
+ G + + S + E T G + +G++
Sbjct: 682 VAGGTQRPAEDSSSSEES-----------------DSEEEKTGLAVTVGQAKSVGKGLQV 724
Query: 436 RPRQKKTQACLASKHVQEAP-RLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSA 494
+ + L P + P + E EDSE +DS +A S A + ++
Sbjct: 725 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
Query: 495 VKQLQ 499
VK+ Q
Sbjct: 785 VKKTQ 789
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 11/239 (4%)
Query: 185 DTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEG-SQAG 243
D +++ Q LS GG+ E + KS+K KK + N + TLA+ +Q
Sbjct: 1242 DGKQEAKPQQAAGMLSPKTGGK--EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCL 1299
Query: 244 REAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEV 303
+ E+Q + +LL KK K+ E + G Q +
Sbjct: 1300 LGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKL-SGDQPAART 1358
Query: 304 GADMQESRPAVGLHGETAGIP---APAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEG 360
++ + G GE + P + K K+K+ K + +E + S +
Sbjct: 1359 PRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPE 1418
Query: 361 SQVGSEVGTVEG----STALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSE 415
++ +GTVEG + K K+ + +KK K++K K + S D PS+ +
Sbjct: 1419 EELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1477
Score = 39.3 bits (90), Expect = 0.017
Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 20/303 (6%)
Query: 172 QRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNR-- 229
Q KA+ SQ + P ES ++ + + P G+ A A K ++ + SS
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGA--APAPPGKTGPAVAKAQAGKREEDSQSSSEESD 418
Query: 230 ---EYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGP------THKKKSKKKKK 280
E A P G A + + P G P+ GP K++ +
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 478
Query: 281 KKSNHQEFEALAMPEGSQVGSEVGADMQ---ESRPAVGLHGETAGIPAPAYKNKSKKKKK 337
+ + + EALA +QV +G Q S +G G+ AG P + +
Sbjct: 479 SEESDSDREALAAMNAAQV-KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
Query: 338 KSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSV 397
+E + ES +S+ E + L+ S+ K +K +V
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 597
Query: 398 K-RARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPR 456
+ +A D+ ++S+S DS E AM K + +T+AC + + +
Sbjct: 598 QVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAK 655
Query: 457 LEP 459
+ P
Sbjct: 656 VAP 658
Score = 39.3 bits (90), Expect = 0.017
Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 28/194 (14%)
Query: 95 EVDEEAGVTVVLVD------KENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVL 148
E +A V VL + K+ ++ T + RK + +S +Q R P++ K + L
Sbjct: 1308 EAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKL 1367
Query: 149 AKSHAHKSEALHSKVREKKNKKHQRKAASWE--SQRARDTL-PQSESHQEESWLSVGPGG 205
++ K K +R AS + ++ + +L Q + E L G G
Sbjct: 1368 GAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMG- 1426
Query: 206 EITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQ 265
T KSKK+KKKS R+ + E + ++A T ES
Sbjct: 1427 --TVEGGDQSNPKSKKEKKKSDKRKKDK-EKKEKKKKAKKASTKDSES------------ 1471
Query: 266 LLGPTHKKKSKKKK 279
P+ KKK KKKK
Sbjct: 1472 ---PSQKKKKKKKK 1482
Score = 35.8 bits (81), Expect = 0.19
Identities = 41/192 (21%), Positives = 79/192 (41%), Gaps = 16/192 (8%)
Query: 115 TPKHFRK--------DVDVVCVDMSIEQKLPRKP-KTDKFQVLAKSHAHKSEALHSKVRE 165
TP+ RK + + +I Q L +P ++ QV A +E L + ++
Sbjct: 1270 TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKK 1329
Query: 166 KKNKKHQRKAASWESQRARDTLPQSESH----QEESWLSVGPGGEITELP---ASAHKNK 218
+ + WES++ + + Q + +++ L G GGE + P ++ K K
Sbjct: 1330 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1389
Query: 219 SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKK 278
+K+ K +E + A E ++Q+ TV D++ KK K+K
Sbjct: 1390 AKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRK 1449
Query: 279 KKKKSNHQEFEA 290
K K+ ++ +A
Sbjct: 1450 KDKEKKEKKKKA 1461
Score = 31.2 bits (69), Expect = 4.6
Identities = 62/305 (20%), Positives = 104/305 (34%), Gaps = 48/305 (15%)
Query: 203 PGGEITELPASAHKNK-------SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQP 255
P G++ SA K S ++ SS+ E T P A ++ ++ +++P
Sbjct: 525 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP----AQEKSLGNILQAKP 580
Query: 256 TVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVG 315
T PQ GP + +K S E S+ S+ AD +E+ A+
Sbjct: 581 TSSPAKGPPQKAGPVAVQVKAEKPMDNS-----------ESSEESSD-SADSEEAPAAM- 627
Query: 316 LHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTA 375
TA PA K K K + A P + + P + G+ S A
Sbjct: 628 ----TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR--KAGTATSPAGSSPA 681
Query: 376 LKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKS 435
+ G + + S + E T G + +G++
Sbjct: 682 VAGGTQRPAEDSSSSEES-----------------DSEEEKTGLAVTVGQAKSVGKGLQV 724
Query: 436 RPRQKKTQACLASKHVQEAP-RLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSA 494
+ + L P + P + E EDSE +DS +A S A + ++
Sbjct: 725 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
Query: 495 VKQLQ 499
VK+ Q
Sbjct: 785 VKKTQ 789
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 11/239 (4%)
Query: 185 DTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEG-SQAG 243
D +++ Q LS GG+ E + KS+K KK + N + TLA+ +Q
Sbjct: 1165 DGKQEAKPQQAAGMLSPKTGGK--EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCL 1222
Query: 244 REAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEV 303
+ E+Q + +LL KK K+ E + G Q +
Sbjct: 1223 LGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKL-SGDQPAART 1281
Query: 304 GADMQESRPAVGLHGETAGIP---APAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEG 360
++ + G GE + P + K K+K+ K + +E + S +
Sbjct: 1282 PRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPE 1341
Query: 361 SQVGSEVGTVEG----STALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSE 415
++ +GTVEG + K K+ + +KK K++K K + S D PS+ +
Sbjct: 1342 EELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1400
Score = 39.3 bits (90), Expect = 0.017
Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 20/303 (6%)
Query: 172 QRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNR-- 229
Q KA+ SQ + P ES ++ + + P G+ A A K ++ + SS
Sbjct: 284 QAKASGKTSQVGAASAPAKESPRKGA--APAPPGKTGPAVAKAQAGKREEDSQSSSEESD 341
Query: 230 ---EYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGP------THKKKSKKKKK 280
E A P G A + + P G P+ GP K++ +
Sbjct: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 401
Query: 281 KKSNHQEFEALAMPEGSQVGSEVGADMQ---ESRPAVGLHGETAGIPAPAYKNKSKKKKK 337
+ + + EALA +QV +G Q S +G G+ AG P + +
Sbjct: 402 SEESDSDREALAAMNAAQV-KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 460
Query: 338 KSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSV 397
+E + ES +S+ E + L+ S+ K +K +V
Sbjct: 461 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 520
Query: 398 K-RARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPR 456
+ +A D+ ++S+S DS E AM K + +T+AC + + +
Sbjct: 521 QVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAK 578
Query: 457 LEP 459
+ P
Sbjct: 579 VAP 581
Score = 39.3 bits (90), Expect = 0.017
Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 28/194 (14%)
Query: 95 EVDEEAGVTVVLVD------KENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVL 148
E +A V VL + K+ ++ T + RK + +S +Q R P++ K + L
Sbjct: 1231 EAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKL 1290
Query: 149 AKSHAHKSEALHSKVREKKNKKHQRKAASWE--SQRARDTL-PQSESHQEESWLSVGPGG 205
++ K K +R AS + ++ + +L Q + E L G G
Sbjct: 1291 GAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMG- 1349
Query: 206 EITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQ 265
T KSKK+KKKS R+ + E + ++A T ES
Sbjct: 1350 --TVEGGDQSNPKSKKEKKKSDKRKKDK-EKKEKKKKAKKASTKDSES------------ 1394
Query: 266 LLGPTHKKKSKKKK 279
P+ KKK KKKK
Sbjct: 1395 ---PSQKKKKKKKK 1405
Score = 35.8 bits (81), Expect = 0.19
Identities = 41/192 (21%), Positives = 79/192 (41%), Gaps = 16/192 (8%)
Query: 115 TPKHFRK--------DVDVVCVDMSIEQKLPRKP-KTDKFQVLAKSHAHKSEALHSKVRE 165
TP+ RK + + +I Q L +P ++ QV A +E L + ++
Sbjct: 1193 TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKK 1252
Query: 166 KKNKKHQRKAASWESQRARDTLPQSESH----QEESWLSVGPGGEITELP---ASAHKNK 218
+ + WES++ + + Q + +++ L G GGE + P ++ K K
Sbjct: 1253 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1312
Query: 219 SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKK 278
+K+ K +E + A E ++Q+ TV D++ KK K+K
Sbjct: 1313 AKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRK 1372
Query: 279 KKKKSNHQEFEA 290
K K+ ++ +A
Sbjct: 1373 KDKEKKEKKKKA 1384
Score = 31.2 bits (69), Expect = 4.6
Identities = 62/305 (20%), Positives = 104/305 (34%), Gaps = 48/305 (15%)
Query: 203 PGGEITELPASAHKNK-------SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQP 255
P G++ SA K S ++ SS+ E T P A ++ ++ +++P
Sbjct: 448 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP----AQEKSLGNILQAKP 503
Query: 256 TVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVG 315
T PQ GP + +K S E S+ S+ AD +E+ A+
Sbjct: 504 TSSPAKGPPQKAGPVAVQVKAEKPMDNS-----------ESSEESSD-SADSEEAPAAM- 550
Query: 316 LHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTA 375
TA PA K K K + A P + + P + G+ S A
Sbjct: 551 ----TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR--KAGTATSPAGSSPA 604
Query: 376 LKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKS 435
+ G + + S + E T G + +G++
Sbjct: 605 VAGGTQRPAEDSSSSEES-----------------DSEEEKTGLAVTVGQAKSVGKGLQV 647
Query: 436 RPRQKKTQACLASKHVQEAP-RLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSA 494
+ + L P + P + E EDSE +DS +A S A + ++
Sbjct: 648 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 707
Query: 495 VKQLQ 499
VK+ Q
Sbjct: 708 VKKTQ 712
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 11/239 (4%)
Query: 185 DTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEG-SQAG 243
D +++ Q LS GG+ E + KS+K KK + N + TLA+ +Q
Sbjct: 1204 DGKQEAKPQQAAGMLSPKTGGK--EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCL 1261
Query: 244 REAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEV 303
+ E+Q + +LL KK K+ E + G Q +
Sbjct: 1262 LGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKL-SGDQPAART 1320
Query: 304 GADMQESRPAVGLHGETAGIP---APAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEG 360
++ + G GE + P + K K+K+ K + +E + S +
Sbjct: 1321 PRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPE 1380
Query: 361 SQVGSEVGTVEG----STALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSE 415
++ +GTVEG + K K+ + +KK K++K K + S D PS+ +
Sbjct: 1381 EELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1439
Score = 39.3 bits (90), Expect = 0.017
Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 20/303 (6%)
Query: 172 QRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNR-- 229
Q KA+ SQ + P ES ++ + + P G+ A A K ++ + SS
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGA--APAPPGKTGPAVAKAQAGKREEDSQSSSEESD 418
Query: 230 ---EYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGP------THKKKSKKKKK 280
E A P G A + + P G P+ GP K++ +
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 478
Query: 281 KKSNHQEFEALAMPEGSQVGSEVGADMQ---ESRPAVGLHGETAGIPAPAYKNKSKKKKK 337
+ + + EALA +QV +G Q S +G G+ AG P + +
Sbjct: 479 SEESDSDREALAAMNAAQV-KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
Query: 338 KSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSV 397
+E + ES +S+ E + L+ S+ K +K +V
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 597
Query: 398 K-RARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPR 456
+ +A D+ ++S+S DS E AM K + +T+AC + + +
Sbjct: 598 QVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAK 655
Query: 457 LEP 459
+ P
Sbjct: 656 VAP 658
Score = 39.3 bits (90), Expect = 0.017
Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 28/194 (14%)
Query: 95 EVDEEAGVTVVLVD------KENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVL 148
E +A V VL + K+ ++ T + RK + +S +Q R P++ K + L
Sbjct: 1270 EAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKL 1329
Query: 149 AKSHAHKSEALHSKVREKKNKKHQRKAASWE--SQRARDTL-PQSESHQEESWLSVGPGG 205
++ K K +R AS + ++ + +L Q + E L G G
Sbjct: 1330 GAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMG- 1388
Query: 206 EITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQ 265
T KSKK+KKKS R+ + E + ++A T ES
Sbjct: 1389 --TVEGGDQSNPKSKKEKKKSDKRKKDK-EKKEKKKKAKKASTKDSES------------ 1433
Query: 266 LLGPTHKKKSKKKK 279
P+ KKK KKKK
Sbjct: 1434 ---PSQKKKKKKKK 1444
Score = 35.8 bits (81), Expect = 0.19
Identities = 41/192 (21%), Positives = 79/192 (41%), Gaps = 16/192 (8%)
Query: 115 TPKHFRK--------DVDVVCVDMSIEQKLPRKP-KTDKFQVLAKSHAHKSEALHSKVRE 165
TP+ RK + + +I Q L +P ++ QV A +E L + ++
Sbjct: 1232 TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKK 1291
Query: 166 KKNKKHQRKAASWESQRARDTLPQSESH----QEESWLSVGPGGEITELP---ASAHKNK 218
+ + WES++ + + Q + +++ L G GGE + P ++ K K
Sbjct: 1292 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1351
Query: 219 SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKK 278
+K+ K +E + A E ++Q+ TV D++ KK K+K
Sbjct: 1352 AKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRK 1411
Query: 279 KKKKSNHQEFEA 290
K K+ ++ +A
Sbjct: 1412 KDKEKKEKKKKA 1423
Score = 31.2 bits (69), Expect = 4.6
Identities = 62/305 (20%), Positives = 104/305 (34%), Gaps = 48/305 (15%)
Query: 203 PGGEITELPASAHKNK-------SKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQP 255
P G++ SA K S ++ SS+ E T P A ++ ++ +++P
Sbjct: 525 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP----AQEKSLGNILQAKP 580
Query: 256 TVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVG 315
T PQ GP + +K S E S+ S+ AD +E+ A+
Sbjct: 581 TSSPAKGPPQKAGPVAVQVKAEKPMDNS-----------ESSEESSD-SADSEEAPAAM- 627
Query: 316 LHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTA 375
TA PA K K K + A P + + P + G+ S A
Sbjct: 628 ----TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR--KAGTATSPAGSSPA 681
Query: 376 LKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKS 435
+ G + + S + E T G + +G++
Sbjct: 682 VAGGTQRPAEDSSSSEES-----------------DSEEEKTGLAVTVGQAKSVGKGLQV 724
Query: 436 RPRQKKTQACLASKHVQEAP-RLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSA 494
+ + L P + P + E EDSE +DS +A S A + ++
Sbjct: 725 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
Query: 495 VKQLQ 499
VK+ Q
Sbjct: 785 VKKTQ 789
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,384,218
Number of Sequences: 37866
Number of extensions: 1608735
Number of successful extensions: 8481
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 393
Number of HSP's that attempted gapping in prelim test: 6824
Number of HSP's gapped (non-prelim): 1478
length of query: 905
length of database: 18,247,518
effective HSP length: 111
effective length of query: 794
effective length of database: 14,044,392
effective search space: 11151247248
effective search space used: 11151247248
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.