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Search of human proteins with 124028521
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124028521 hematopoietic transcription factor PU.1 isoform 1
[Homo sapiens]
(271 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124028521 hematopoietic transcription factor PU.1 isoform 1 [... 574 e-164
gi|124028517 hematopoietic transcription factor PU.1 isoform 2 [... 568 e-162
gi|61888836 Spi-B transcription factor (Spi-1/PU.1 related) [Hom... 174 7e-44
gi|22748707 Spi-C transcription factor (Spi-1/PU.1 related) [Hom... 121 7e-28
gi|34452721 GA binding protein transcription factor, alpha subun... 64 1e-10
gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens] 62 5e-10
gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens] 62 5e-10
gi|6912580 SAM pointed domain containing ets transcription facto... 57 2e-08
gi|11496882 ELK4 protein isoform b [Homo sapiens] 56 4e-08
gi|41872448 ELK4 protein isoform a [Homo sapiens] 56 4e-08
gi|4885221 v-ets erythroblastosis virus E26 oncogene homolog 2 [... 55 5e-08
gi|166362732 ELK1 protein [Homo sapiens] 54 1e-07
gi|166362730 ELK1 protein [Homo sapiens] 54 1e-07
gi|27436883 ets homologous factor [Homo sapiens] 54 1e-07
gi|8923789 FEV (ETS oncogene family) [Homo sapiens] 53 2e-07
gi|27363484 E74-like factor 1 (ets domain transcription factor) ... 53 3e-07
gi|223941929 E74-like factor 1 (ets domain transcription factor)... 53 3e-07
gi|253683437 ets variant gene 1 isoform f [Homo sapiens] 53 3e-07
gi|253683435 ets variant gene 1 isoform e [Homo sapiens] 53 3e-07
gi|253683433 ets variant gene 1 isoform d [Homo sapiens] 53 3e-07
gi|253683431 ets variant gene 1 isoform c [Homo sapiens] 53 3e-07
gi|253683429 ets variant gene 1 isoform c [Homo sapiens] 53 3e-07
gi|31742534 ets variant gene 1 isoform a [Homo sapiens] 53 3e-07
gi|7110593 Friend leukemia virus integration 1 [Homo sapiens] 52 5e-07
gi|42544172 E74-like factor 2 (ets domain transcription factor) ... 52 5e-07
gi|6857816 E74-like factor 2 (ets domain transcription factor) i... 52 5e-07
gi|209954808 ets-related isoform 4 [Homo sapiens] 51 9e-07
gi|33667107 ets-related isoform 1 [Homo sapiens] 51 9e-07
gi|209954797 ets-related isoform 3 [Homo sapiens] 51 9e-07
gi|153791178 ets variant gene 2 [Homo sapiens] 51 9e-07
>gi|124028521 hematopoietic transcription factor PU.1 isoform 1
[Homo sapiens]
Length = 271
Score = 574 bits (1480), Expect = e-164
Identities = 271/271 (100%), Positives = 271/271 (100%)
Query: 1 MLQACKMEGFPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH 60
MLQACKMEGFPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH
Sbjct: 1 MLQACKMEGFPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH 60
Query: 61 SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL 120
SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL
Sbjct: 61 SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL 120
Query: 121 QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL 180
QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL
Sbjct: 121 QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL 180
Query: 181 LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG 240
LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG
Sbjct: 181 LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG 240
Query: 241 EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH 271
EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH
Sbjct: 241 EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH 271
>gi|124028517 hematopoietic transcription factor PU.1 isoform 2
[Homo sapiens]
Length = 270
Score = 568 bits (1463), Expect = e-162
Identities = 270/271 (99%), Positives = 270/271 (99%), Gaps = 1/271 (0%)
Query: 1 MLQACKMEGFPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH 60
MLQACKMEGFPLVPP PSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH
Sbjct: 1 MLQACKMEGFPLVPP-PSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH 59
Query: 61 SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL 120
SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL
Sbjct: 60 SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL 119
Query: 121 QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL 180
QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL
Sbjct: 120 QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL 179
Query: 181 LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG 240
LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG
Sbjct: 180 LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG 239
Query: 241 EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH 271
EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH
Sbjct: 240 EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH 270
>gi|61888836 Spi-B transcription factor (Spi-1/PU.1 related) [Homo
sapiens]
Length = 262
Score = 174 bits (441), Expect = 7e-44
Identities = 117/268 (43%), Positives = 150/268 (55%), Gaps = 26/268 (9%)
Query: 2 LQACKMEG--FPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFH--PH 57
L+A +++G F + P D V YD D + H YP D E D WD+ P
Sbjct: 4 LEAAQLDGPHFSCLYP----DGVFYDLDSCK---HSSYP----DSEGAPDSLWDWTVAPP 52
Query: 58 HVHSEFESF--AENNFTELQSVQ---PPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQV 112
+ +E+F A F+ Q+ Q P ++EL P +P +P+
Sbjct: 53 VPATPYEAFDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFAS 112
Query: 113 SYL-PRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEAD-GLEPGPGLLPGETGSKKK 170
L P YPS S+EE+ SP LEVSD E+D L GP E G++KK
Sbjct: 113 QTLVPPAYAPYPS----PVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKK 168
Query: 171 IRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMA 230
+RLYQFLL LL GDM++ +WWV+ G FQFSSKHKE LA RWG QKGNRK+MTYQK+A
Sbjct: 169 LRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLA 228
Query: 231 RALRNYGKTGEVKKVKKKLTYQFSGEVL 258
RALRNY KTGE++KVK+KLTYQF +L
Sbjct: 229 RALRNYAKTGEIRKVKRKLTYQFDSALL 256
>gi|22748707 Spi-C transcription factor (Spi-1/PU.1 related) [Homo
sapiens]
Length = 248
Score = 121 bits (303), Expect = 7e-28
Identities = 60/104 (57%), Positives = 78/104 (75%), Gaps = 1/104 (0%)
Query: 158 PGLLPGETGS-KKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGI 216
P LL + G +KK+RL+++L + L + +M I WVDK KG FQF SK+KE LA WG
Sbjct: 97 PTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGK 156
Query: 217 QKGNRKKMTYQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGR 260
+KGNRK MTYQKMARALRNYG++GE+ K+++KLTYQFS +L R
Sbjct: 157 RKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQR 200
>gi|34452721 GA binding protein transcription factor, alpha subunit
[Homo sapiens]
Length = 454
Score = 63.9 bits (154), Expect = 1e-10
Identities = 52/178 (29%), Positives = 90/178 (50%), Gaps = 17/178 (9%)
Query: 80 PQLQQLYRHMELEQMHVLDTPMVPPHP--SLGHQVSYLPRMCLQY-PSLSPAQPSSDEEE 136
P+ + L+ H+EL + +VL + + ++ V +P P+ SS +
Sbjct: 235 PRGEILWSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAA 294
Query: 137 GERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKD 196
+++P + D + G TG+ +I+L+QFLL+LL D +D I WV D
Sbjct: 295 KVQRAPRISGEDRSSPG---------NRTGNNGQIQLWQFLLELLTDKDARDCISWVG-D 344
Query: 197 KGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQF 253
+G F+ + E +A +WG Q+ N+ M Y+K++RALR Y + KV+ K+ Y+F
Sbjct: 345 EGEFKLN--QPELVAQKWG-QRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKF 399
>gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens]
Length = 265
Score = 62.0 bits (149), Expect = 5e-10
Identities = 37/94 (39%), Positives = 57/94 (60%), Gaps = 4/94 (4%)
Query: 167 SKKKIRLYQFLLDLLRSGDMKDSIW-WVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMT 225
S + L++F+ DLL S + I W D+++G F+ EALA WG +K N +MT
Sbjct: 169 SLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKS--EALAKMWGQRKKN-DRMT 225
Query: 226 YQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLG 259
Y+K++RALR Y KTG +++V ++L Y+F G
Sbjct: 226 YEKLSRALRYYYKTGILERVDRRLVYKFGKNAHG 259
>gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens]
Length = 255
Score = 62.0 bits (149), Expect = 5e-10
Identities = 37/94 (39%), Positives = 57/94 (60%), Gaps = 4/94 (4%)
Query: 167 SKKKIRLYQFLLDLLRSGDMKDSIW-WVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMT 225
S + L++F+ DLL S + I W D+++G F+ EALA WG +K N +MT
Sbjct: 159 SLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKS--EALAKMWGQRKKN-DRMT 215
Query: 226 YQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLG 259
Y+K++RALR Y KTG +++V ++L Y+F G
Sbjct: 216 YEKLSRALRYYYKTGILERVDRRLVYKFGKNAHG 249
>gi|6912580 SAM pointed domain containing ets transcription factor
[Homo sapiens]
Length = 335
Score = 56.6 bits (135), Expect = 2e-08
Identities = 34/90 (37%), Positives = 54/90 (60%), Gaps = 6/90 (6%)
Query: 167 SKKKIRLYQFLLDLL-RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMT 225
S + I L+QFL +LL + I W++K+KG F+ + +A WGI+K NR M
Sbjct: 245 SGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQ--VARLWGIRK-NRPAMN 301
Query: 226 YQKMARALRNYGKTGEVKK--VKKKLTYQF 253
Y K++R++R Y K G ++K + ++L YQF
Sbjct: 302 YDKLSRSIRQYYKKGIIRKPDISQRLVYQF 331
>gi|11496882 ELK4 protein isoform b [Homo sapiens]
Length = 405
Score = 55.8 bits (133), Expect = 4e-08
Identities = 35/84 (41%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 171 IRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMA 230
I L+QFLL LL+ K I W D QF E +A WGI+K N+ M Y K++
Sbjct: 5 ITLWQFLLQLLQKPQNKHMICWTSNDG---QFKLLQAEEVARLWGIRK-NKPNMNYDKLS 60
Query: 231 RALRNYGKTGEVKKVK-KKLTYQF 253
RALR Y +KKV +K Y+F
Sbjct: 61 RALRYYYVKNIIKKVNGQKFVYKF 84
>gi|41872448 ELK4 protein isoform a [Homo sapiens]
Length = 431
Score = 55.8 bits (133), Expect = 4e-08
Identities = 35/84 (41%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 171 IRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMA 230
I L+QFLL LL+ K I W D QF E +A WGI+K N+ M Y K++
Sbjct: 5 ITLWQFLLQLLQKPQNKHMICWTSNDG---QFKLLQAEEVARLWGIRK-NKPNMNYDKLS 60
Query: 231 RALRNYGKTGEVKKVK-KKLTYQF 253
RALR Y +KKV +K Y+F
Sbjct: 61 RALRYYYVKNIIKKVNGQKFVYKF 84
>gi|4885221 v-ets erythroblastosis virus E26 oncogene homolog 2
[Homo sapiens]
Length = 469
Score = 55.5 bits (132), Expect = 5e-08
Identities = 47/162 (29%), Positives = 72/162 (44%), Gaps = 19/162 (11%)
Query: 93 QMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEAD 152
Q +LD VP S S +CL P++S + + Q P+ +
Sbjct: 299 QSSLLDVQRVPSFESFEDDCSQ--SLCLNKPTMSFKDYIQERSDPVEQGKPVIPA----- 351
Query: 153 GLEPGPGLLPGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAH 212
+L G TGS I+L+QFLL+LL + I W ++F + +A
Sbjct: 352 ------AVLAGFTGSGP-IQLWQFLLELLSDKSCQSFISWTGDG---WEFKLADPDEVAR 401
Query: 213 RWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQF 253
RWG +K N+ KM Y+K++R LR Y + K K+ Y+F
Sbjct: 402 RWGKRK-NKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRF 442
>gi|166362732 ELK1 protein [Homo sapiens]
Length = 428
Score = 53.9 bits (128), Expect = 1e-07
Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 171 IRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMA 230
+ L+QFLL LLR I W +D G F+ E +A WG++K N+ M Y K++
Sbjct: 5 VTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVD--AEEVARLWGLRK-NKTNMNYDKLS 61
Query: 231 RALRNYGKTGEVKKVK-KKLTYQF 253
RALR Y ++KV +K Y+F
Sbjct: 62 RALRYYYDKNIIRKVSGQKFVYKF 85
>gi|166362730 ELK1 protein [Homo sapiens]
Length = 428
Score = 53.9 bits (128), Expect = 1e-07
Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 171 IRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMA 230
+ L+QFLL LLR I W +D G F+ E +A WG++K N+ M Y K++
Sbjct: 5 VTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVD--AEEVARLWGLRK-NKTNMNYDKLS 61
Query: 231 RALRNYGKTGEVKKVK-KKLTYQF 253
RALR Y ++KV +K Y+F
Sbjct: 62 RALRYYYDKNIIRKVSGQKFVYKF 85
>gi|27436883 ets homologous factor [Homo sapiens]
Length = 300
Score = 53.9 bits (128), Expect = 1e-07
Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 5/89 (5%)
Query: 173 LYQFLLDLLRSGDMKDS-IWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMAR 231
L++F+ D+L + D I W D+ +G F+F EA+A WG +K N MTY+K++R
Sbjct: 209 LWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKS--EAVAQLWG-KKKNNSSMTYEKLSR 265
Query: 232 ALRNYGKTGEVKKVK-KKLTYQFSGEVLG 259
A+R Y K +++V ++L Y+F G
Sbjct: 266 AMRYYYKREILERVDGRRLVYKFGKNARG 294
>gi|8923789 FEV (ETS oncogene family) [Homo sapiens]
Length = 238
Score = 53.1 bits (126), Expect = 2e-07
Identities = 45/131 (34%), Positives = 63/131 (48%), Gaps = 12/131 (9%)
Query: 143 PLEVSDGE-ADGLEPGPG-LLPGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTF 200
P V DG DG P G L P +I+L+QFLL+LL I W + G
Sbjct: 17 PDPVGDGLFKDGKNPSWGPLSPAVQKGSGQIQLWQFLLELLADRANAGCIAW---EGGHG 73
Query: 201 QFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQFSGEVLG 259
+F + +A RWG +K ++ M Y K++RALR Y + KV K+ Y+F +
Sbjct: 74 EFKLTDPDEVARRWGERK-SKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRFDFQ--- 129
Query: 260 RGGLAERRHPP 270
GLA+ PP
Sbjct: 130 --GLAQACQPP 138
>gi|27363484 E74-like factor 1 (ets domain transcription factor)
isoform a [Homo sapiens]
Length = 619
Score = 52.8 bits (125), Expect = 3e-07
Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 10/130 (7%)
Query: 126 SPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLLRS-G 184
SP QP ++G + PP S + + G I L++FLL LL+
Sbjct: 168 SPEQPK--RKKGRKTKPPRPDSPATTPNISVKK---KNKDGKGNTIYLWEFLLALLQDKA 222
Query: 185 DMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKK 244
I W ++KG F+ +A++ WG K N+ M Y+ M RALR Y + G + K
Sbjct: 223 TCPKYIKWTQREKGIFKLVDS--KAVSRLWGKHK-NKPDMNYETMGRALRYYYQRGILAK 279
Query: 245 VK-KKLTYQF 253
V+ ++L YQF
Sbjct: 280 VEGQRLVYQF 289
>gi|223941929 E74-like factor 1 (ets domain transcription factor)
isoform b [Homo sapiens]
Length = 595
Score = 52.8 bits (125), Expect = 3e-07
Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 10/130 (7%)
Query: 126 SPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLLRS-G 184
SP QP ++G + PP S + + G I L++FLL LL+
Sbjct: 144 SPEQPK--RKKGRKTKPPRPDSPATTPNISVKK---KNKDGKGNTIYLWEFLLALLQDKA 198
Query: 185 DMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKK 244
I W ++KG F+ +A++ WG K N+ M Y+ M RALR Y + G + K
Sbjct: 199 TCPKYIKWTQREKGIFKLVDS--KAVSRLWGKHK-NKPDMNYETMGRALRYYYQRGILAK 255
Query: 245 VK-KKLTYQF 253
V+ ++L YQF
Sbjct: 256 VEGQRLVYQF 265
>gi|253683437 ets variant gene 1 isoform f [Homo sapiens]
Length = 374
Score = 52.8 bits (125), Expect = 3e-07
Identities = 68/253 (26%), Positives = 105/253 (41%), Gaps = 44/253 (17%)
Query: 10 FPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHSEFESFAEN 69
FP +P P E +YQRQ E P + + Y D P + H+ A +
Sbjct: 94 FPPLPTMPREG-----RPMYQRQMSE--PNIPFPPQGFKQEYHD--PVYEHNTMVGSAAS 144
Query: 70 NFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQ 129
QS PP + + + + D+ + H Q +L A
Sbjct: 145 -----QSFPPPLMIK-----QEPRDFAYDSEVPSCHSIYMRQEGFL------------AH 182
Query: 130 PSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLDLL 181
PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+ LL
Sbjct: 183 PSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALL 242
Query: 182 RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE 241
I W + +F E +A RWGIQK NR M Y K++R+LR Y + G
Sbjct: 243 DDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEKGI 298
Query: 242 VKKVK-KKLTYQF 253
++KV ++ Y+F
Sbjct: 299 MQKVAGERYVYKF 311
>gi|253683435 ets variant gene 1 isoform e [Homo sapiens]
Length = 419
Score = 52.8 bits (125), Expect = 3e-07
Identities = 68/253 (26%), Positives = 105/253 (41%), Gaps = 44/253 (17%)
Query: 10 FPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHSEFESFAEN 69
FP +P P E +YQRQ E P + + Y D P + H+ A +
Sbjct: 139 FPPLPTMPREG-----RPMYQRQMSE--PNIPFPPQGFKQEYHD--PVYEHNTMVGSAAS 189
Query: 70 NFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQ 129
QS PP + + + + D+ + H Q +L A
Sbjct: 190 -----QSFPPPLMIK-----QEPRDFAYDSEVPSCHSIYMRQEGFL------------AH 227
Query: 130 PSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLDLL 181
PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+ LL
Sbjct: 228 PSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALL 287
Query: 182 RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE 241
I W + +F E +A RWGIQK NR M Y K++R+LR Y + G
Sbjct: 288 DDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEKGI 343
Query: 242 VKKVK-KKLTYQF 253
++KV ++ Y+F
Sbjct: 344 MQKVAGERYVYKF 356
>gi|253683433 ets variant gene 1 isoform d [Homo sapiens]
Length = 437
Score = 52.8 bits (125), Expect = 3e-07
Identities = 68/253 (26%), Positives = 105/253 (41%), Gaps = 44/253 (17%)
Query: 10 FPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHSEFESFAEN 69
FP +P P E +YQRQ E P + + Y D P + H+ A +
Sbjct: 157 FPPLPTMPREG-----RPMYQRQMSE--PNIPFPPQGFKQEYHD--PVYEHNTMVGSAAS 207
Query: 70 NFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQ 129
QS PP + + + + D+ + H Q +L A
Sbjct: 208 -----QSFPPPLMIK-----QEPRDFAYDSEVPSCHSIYMRQEGFL------------AH 245
Query: 130 PSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLDLL 181
PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+ LL
Sbjct: 246 PSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALL 305
Query: 182 RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE 241
I W + +F E +A RWGIQK NR M Y K++R+LR Y + G
Sbjct: 306 DDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEKGI 361
Query: 242 VKKVK-KKLTYQF 253
++KV ++ Y+F
Sbjct: 362 MQKVAGERYVYKF 374
>gi|253683431 ets variant gene 1 isoform c [Homo sapiens]
Length = 459
Score = 52.8 bits (125), Expect = 3e-07
Identities = 68/253 (26%), Positives = 105/253 (41%), Gaps = 44/253 (17%)
Query: 10 FPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHSEFESFAEN 69
FP +P P E +YQRQ E P + + Y D P + H+ A +
Sbjct: 179 FPPLPTMPREG-----RPMYQRQMSE--PNIPFPPQGFKQEYHD--PVYEHNTMVGSAAS 229
Query: 70 NFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQ 129
QS PP + + + + D+ + H Q +L A
Sbjct: 230 -----QSFPPPLMIK-----QEPRDFAYDSEVPSCHSIYMRQEGFL------------AH 267
Query: 130 PSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLDLL 181
PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+ LL
Sbjct: 268 PSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALL 327
Query: 182 RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE 241
I W + +F E +A RWGIQK NR M Y K++R+LR Y + G
Sbjct: 328 DDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEKGI 383
Query: 242 VKKVK-KKLTYQF 253
++KV ++ Y+F
Sbjct: 384 MQKVAGERYVYKF 396
>gi|253683429 ets variant gene 1 isoform c [Homo sapiens]
Length = 459
Score = 52.8 bits (125), Expect = 3e-07
Identities = 68/253 (26%), Positives = 105/253 (41%), Gaps = 44/253 (17%)
Query: 10 FPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHSEFESFAEN 69
FP +P P E +YQRQ E P + + Y D P + H+ A +
Sbjct: 179 FPPLPTMPREG-----RPMYQRQMSE--PNIPFPPQGFKQEYHD--PVYEHNTMVGSAAS 229
Query: 70 NFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQ 129
QS PP + + + + D+ + H Q +L A
Sbjct: 230 -----QSFPPPLMIK-----QEPRDFAYDSEVPSCHSIYMRQEGFL------------AH 267
Query: 130 PSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLDLL 181
PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+ LL
Sbjct: 268 PSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALL 327
Query: 182 RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE 241
I W + +F E +A RWGIQK NR M Y K++R+LR Y + G
Sbjct: 328 DDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEKGI 383
Query: 242 VKKVK-KKLTYQF 253
++KV ++ Y+F
Sbjct: 384 MQKVAGERYVYKF 396
>gi|31742534 ets variant gene 1 isoform a [Homo sapiens]
Length = 477
Score = 52.8 bits (125), Expect = 3e-07
Identities = 68/253 (26%), Positives = 105/253 (41%), Gaps = 44/253 (17%)
Query: 10 FPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHSEFESFAEN 69
FP +P P E +YQRQ E P + + Y D P + H+ A +
Sbjct: 197 FPPLPTMPREG-----RPMYQRQMSE--PNIPFPPQGFKQEYHD--PVYEHNTMVGSAAS 247
Query: 70 NFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQ 129
QS PP + + + + D+ + H Q +L A
Sbjct: 248 -----QSFPPPLMIK-----QEPRDFAYDSEVPSCHSIYMRQEGFL------------AH 285
Query: 130 PSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLDLL 181
PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+ LL
Sbjct: 286 PSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALL 345
Query: 182 RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE 241
I W + +F E +A RWGIQK NR M Y K++R+LR Y + G
Sbjct: 346 DDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEKGI 401
Query: 242 VKKVK-KKLTYQF 253
++KV ++ Y+F
Sbjct: 402 MQKVAGERYVYKF 414
>gi|7110593 Friend leukemia virus integration 1 [Homo sapiens]
Length = 452
Score = 52.0 bits (123), Expect = 5e-07
Identities = 44/144 (30%), Positives = 68/144 (47%), Gaps = 17/144 (11%)
Query: 122 YPSLSPAQPSSDEEEGERQSPPL----EVSDGEADGLEPGPGLLPGETGSKK------KI 171
Y S+ ++ G +SPPL +S +P P + G T S+ +I
Sbjct: 222 YDSVRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQI 281
Query: 172 RLYQFLLDLLRSGDMKDSIWWVDKDKGTF-QFSSKHKEALAHRWGIQKGNRKKMTYQKMA 230
+L+QFLL+LL I W +GT +F + +A RWG +K ++ M Y K++
Sbjct: 282 QLWQFLLELLSDSANASCITW----EGTNGEFKMTDPDEVARRWGERK-SKPNMNYDKLS 336
Query: 231 RALRNYGKTGEVKKVK-KKLTYQF 253
RALR Y + KV K+ Y+F
Sbjct: 337 RALRYYYDKNIMTKVHGKRYAYKF 360
>gi|42544172 E74-like factor 2 (ets domain transcription factor)
isoform 1 [Homo sapiens]
Length = 581
Score = 52.0 bits (123), Expect = 5e-07
Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 13/100 (13%)
Query: 164 ETGSKKKIR--------LYQFLLDLLRSGDMKDS-IWWVDKDKGTFQFSSKHKEALAHRW 214
E G KKK R L++FLLDLL+ + I W ++KG F+ +A++ W
Sbjct: 181 ELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDS--KAVSKLW 238
Query: 215 GIQKGNRKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQF 253
G K N+ M Y+ M RALR Y + G + KV+ ++L YQF
Sbjct: 239 GKHK-NKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQF 277
>gi|6857816 E74-like factor 2 (ets domain transcription factor)
isoform 2 [Homo sapiens]
Length = 533
Score = 52.0 bits (123), Expect = 5e-07
Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 13/100 (13%)
Query: 164 ETGSKKKIR--------LYQFLLDLLRSGDMKDS-IWWVDKDKGTFQFSSKHKEALAHRW 214
E G KKK R L++FLLDLL+ + I W ++KG F+ +A++ W
Sbjct: 133 ELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDS--KAVSKLW 190
Query: 215 GIQKGNRKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQF 253
G K N+ M Y+ M RALR Y + G + KV+ ++L YQF
Sbjct: 191 GKHK-NKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQF 229
>gi|209954808 ets-related isoform 4 [Homo sapiens]
Length = 387
Score = 51.2 bits (121), Expect = 9e-07
Identities = 75/277 (27%), Positives = 114/277 (41%), Gaps = 48/277 (17%)
Query: 3 QACKM--EGFPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH 60
+ CKM + F + P + D++ Y R+T P+L+SD D P +H
Sbjct: 75 ELCKMTKDDFQRLTPSYNADILLSHLH-YLRETP--LPHLTSDDV---DKALQNSPRLMH 128
Query: 61 SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSL----GHQVSYLP 116
+ A F SV P Q++ +L P PP S GH P
Sbjct: 129 ARNTGGAAFIFPNT-SVYPEATQRITTRPDL--------PYEPPRRSAWTGHGHPT---P 176
Query: 117 RMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGL-EPGPGLLPGETGSKKKIRLYQ 175
+ PS S + D+ Q P ++ + L PG G +I+L+Q
Sbjct: 177 QSKAAQPSPSTVPKTEDQRP---QLDPYQILGPTSSRLANPGSG----------QIQLWQ 223
Query: 176 FLLDLLRSGDMKDSIWWVDKDKGT-FQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALR 234
FLL+LL I W +GT +F + +A RWG +K ++ M Y K++RALR
Sbjct: 224 FLLELLSDSSNSSCITW----EGTNGEFKMTDPDEVARRWGERK-SKPNMNYDKLSRALR 278
Query: 235 NYGKTGEVKKVK-KKLTYQFSGEVLGRGGLAERRHPP 270
Y + KV K+ Y+F + + A + HPP
Sbjct: 279 YYYDKNIMTKVHGKRYAYKFDFHGIAQ---ALQPHPP 312
>gi|33667107 ets-related isoform 1 [Homo sapiens]
Length = 479
Score = 51.2 bits (121), Expect = 9e-07
Identities = 75/277 (27%), Positives = 114/277 (41%), Gaps = 48/277 (17%)
Query: 3 QACKM--EGFPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH 60
+ CKM + F + P + D++ Y R+T P+L+SD D P +H
Sbjct: 167 ELCKMTKDDFQRLTPSYNADILLSHLH-YLRETP--LPHLTSDDV---DKALQNSPRLMH 220
Query: 61 SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSL----GHQVSYLP 116
+ A F SV P Q++ +L P PP S GH P
Sbjct: 221 ARNTGGAAFIFPNT-SVYPEATQRITTRPDL--------PYEPPRRSAWTGHGHPT---P 268
Query: 117 RMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGL-EPGPGLLPGETGSKKKIRLYQ 175
+ PS S + D+ Q P ++ + L PG G +I+L+Q
Sbjct: 269 QSKAAQPSPSTVPKTEDQRP---QLDPYQILGPTSSRLANPGSG----------QIQLWQ 315
Query: 176 FLLDLLRSGDMKDSIWWVDKDKGT-FQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALR 234
FLL+LL I W +GT +F + +A RWG +K ++ M Y K++RALR
Sbjct: 316 FLLELLSDSSNSSCITW----EGTNGEFKMTDPDEVARRWGERK-SKPNMNYDKLSRALR 370
Query: 235 NYGKTGEVKKVK-KKLTYQFSGEVLGRGGLAERRHPP 270
Y + KV K+ Y+F + + A + HPP
Sbjct: 371 YYYDKNIMTKVHGKRYAYKFDFHGIAQ---ALQPHPP 404
>gi|209954797 ets-related isoform 3 [Homo sapiens]
Length = 486
Score = 51.2 bits (121), Expect = 9e-07
Identities = 75/277 (27%), Positives = 114/277 (41%), Gaps = 48/277 (17%)
Query: 3 QACKM--EGFPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH 60
+ CKM + F + P + D++ Y R+T P+L+SD D P +H
Sbjct: 174 ELCKMTKDDFQRLTPSYNADILLSHLH-YLRETP--LPHLTSDDV---DKALQNSPRLMH 227
Query: 61 SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSL----GHQVSYLP 116
+ A F SV P Q++ +L P PP S GH P
Sbjct: 228 ARNTGGAAFIFPNT-SVYPEATQRITTRPDL--------PYEPPRRSAWTGHGHPT---P 275
Query: 117 RMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGL-EPGPGLLPGETGSKKKIRLYQ 175
+ PS S + D+ Q P ++ + L PG G +I+L+Q
Sbjct: 276 QSKAAQPSPSTVPKTEDQRP---QLDPYQILGPTSSRLANPGSG----------QIQLWQ 322
Query: 176 FLLDLLRSGDMKDSIWWVDKDKGT-FQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALR 234
FLL+LL I W +GT +F + +A RWG +K ++ M Y K++RALR
Sbjct: 323 FLLELLSDSSNSSCITW----EGTNGEFKMTDPDEVARRWGERK-SKPNMNYDKLSRALR 377
Query: 235 NYGKTGEVKKVK-KKLTYQFSGEVLGRGGLAERRHPP 270
Y + KV K+ Y+F + + A + HPP
Sbjct: 378 YYYDKNIMTKVHGKRYAYKFDFHGIAQ---ALQPHPP 411
>gi|153791178 ets variant gene 2 [Homo sapiens]
Length = 342
Score = 51.2 bits (121), Expect = 9e-07
Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 164 ETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKK 223
+T + I+L+QFLL+LL G I W + +F + +A WG +K +
Sbjct: 234 KTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSR---EFQLCDPKEVARLWGERK-RKPG 289
Query: 224 MTYQKMARALRNYGKTGEVKKV-KKKLTYQFSGEV 257
M Y+K++R LR Y + V+K +K TY+F G V
Sbjct: 290 MNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRV 324
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,416,036
Number of Sequences: 37866
Number of extensions: 712157
Number of successful extensions: 2352
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 2276
Number of HSP's gapped (non-prelim): 144
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.