Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 122937428
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937428 phospholipase A2, group 4E [Homo sapiens]
(839 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937428 phospholipase A2, group 4E [Homo sapiens] 1726 0.0
gi|116174754 phospholipase A2, group IVD [Homo sapiens] 672 0.0
gi|167860120 phospholipase A2, group IVB [Homo sapiens] 628 e-180
gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens] 628 e-180
gi|67972429 phospholipase A2, group IVF [Homo sapiens] 574 e-163
gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens] 291 1e-78
gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens] 154 3e-37
gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Ho... 154 3e-37
gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Ho... 154 3e-37
gi|6005997 double C2-like domains, beta [Homo sapiens] 45 2e-04
gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Hom... 44 8e-04
gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Hom... 44 8e-04
gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens] 44 8e-04
gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens] 44 8e-04
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 43 0.001
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 43 0.001
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 43 0.001
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 43 0.001
gi|227496504 multiple C2 domains, transmembrane 2 isoform 3 [Hom... 42 0.002
gi|4506067 protein kinase C, alpha [Homo sapiens] 41 0.004
gi|150170670 piccolo isoform 2 [Homo sapiens] 41 0.004
gi|150378539 piccolo isoform 1 [Homo sapiens] 41 0.004
gi|21361472 neural precursor cell expressed, developmentally dow... 41 0.005
gi|222352086 neural precursor cell expressed, developmentally do... 41 0.005
gi|47078261 double C2-like domains, alpha [Homo sapiens] 40 0.007
gi|38570146 synaptotagmin VII [Homo sapiens] 40 0.009
gi|222352090 neural precursor cell expressed, developmentally do... 40 0.012
gi|222352088 neural precursor cell expressed, developmentally do... 40 0.012
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 40 0.012
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 40 0.012
>gi|122937428 phospholipase A2, group 4E [Homo sapiens]
Length = 839
Score = 1726 bits (4469), Expect = 0.0
Identities = 839/839 (100%), Positives = 839/839 (100%)
Query: 1 MRAKCITEPVGIELAPCLQAPSVPETDLKGVVQARGGGASVLEKPREGFKRAEQVPVSQT 60
MRAKCITEPVGIELAPCLQAPSVPETDLKGVVQARGGGASVLEKPREGFKRAEQVPVSQT
Sbjct: 1 MRAKCITEPVGIELAPCLQAPSVPETDLKGVVQARGGGASVLEKPREGFKRAEQVPVSQT 60
Query: 61 DCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDH 120
DCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDH
Sbjct: 61 DCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDH 120
Query: 121 LLTVLYDLTKLCFRKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSRQVSC 180
LLTVLYDLTKLCFRKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSRQVSC
Sbjct: 121 LLTVLYDLTKLCFRKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSRQVSC 180
Query: 181 LEVHAQSRRRRKREKMKDLLVMVNESFENTQRVRPCLEPCCPTSACFQTAACFHYPKYFQ 240
LEVHAQSRRRRKREKMKDLLVMVNESFENTQRVRPCLEPCCPTSACFQTAACFHYPKYFQ
Sbjct: 181 LEVHAQSRRRRKREKMKDLLVMVNESFENTQRVRPCLEPCCPTSACFQTAACFHYPKYFQ 240
Query: 241 SQVHVEVPKSHWSCGLCCRSRKKGPISQPLDCLSDGQVMTLPVGESYELHMKSTPCPETL 300
SQVHVEVPKSHWSCGLCCRSRKKGPISQPLDCLSDGQVMTLPVGESYELHMKSTPCPETL
Sbjct: 241 SQVHVEVPKSHWSCGLCCRSRKKGPISQPLDCLSDGQVMTLPVGESYELHMKSTPCPETL 300
Query: 301 DVRLGFSLCPAELEFLQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATGGGTRSMTSM 360
DVRLGFSLCPAELEFLQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATGGGTRSMTSM
Sbjct: 301 DVRLGFSLCPAELEFLQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATGGGTRSMTSM 360
Query: 361 YGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSKNLEPAIFEARRHVVKDKLP 420
YGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSKNLEPAIFEARRHVVKDKLP
Sbjct: 361 YGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSKNLEPAIFEARRHVVKDKLP 420
Query: 421 SLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQRAALSCGQNP 480
SLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQRAALSCGQNP
Sbjct: 421 SLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQRAALSCGQNP 480
Query: 481 LPIYLTINVKDDVSNQDFREWFEFSPYEVGLQKYGAFIPSELFGSEFFMGRLVKRIPESR 540
LPIYLTINVKDDVSNQDFREWFEFSPYEVGLQKYGAFIPSELFGSEFFMGRLVKRIPESR
Sbjct: 481 LPIYLTINVKDDVSNQDFREWFEFSPYEVGLQKYGAFIPSELFGSEFFMGRLVKRIPESR 540
Query: 541 ICYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTREKVQDIEDEPILPEIPKCDANILET 600
ICYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTREKVQDIEDEPILPEIPKCDANILET
Sbjct: 541 ICYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTREKVQDIEDEPILPEIPKCDANILET 600
Query: 601 TVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQFSRWKDTVLDGFPNQL 660
TVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQFSRWKDTVLDGFPNQL
Sbjct: 601 TVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQFSRWKDTVLDGFPNQL 660
Query: 661 TESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGSQTKPLKQTCEYCTVQNIP 720
TESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGSQTKPLKQTCEYCTVQNIP
Sbjct: 661 TESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGSQTKPLKQTCEYCTVQNIP 720
Query: 721 FPKYELPDENENLKECYLMENPQEPDAPIVTFFPLINDTFRKYKAPGVERSPEELEQGQV 780
FPKYELPDENENLKECYLMENPQEPDAPIVTFFPLINDTFRKYKAPGVERSPEELEQGQV
Sbjct: 721 FPKYELPDENENLKECYLMENPQEPDAPIVTFFPLINDTFRKYKAPGVERSPEELEQGQV 780
Query: 781 DIYGPKTPYATKELTYTEATFDKLVKLSEYNILNNKDTLLQALRLAVEKKKRLKGQCPS 839
DIYGPKTPYATKELTYTEATFDKLVKLSEYNILNNKDTLLQALRLAVEKKKRLKGQCPS
Sbjct: 781 DIYGPKTPYATKELTYTEATFDKLVKLSEYNILNNKDTLLQALRLAVEKKKRLKGQCPS 839
>gi|116174754 phospholipase A2, group IVD [Homo sapiens]
Length = 818
Score = 672 bits (1734), Expect = 0.0
Identities = 358/794 (45%), Positives = 510/794 (64%), Gaps = 31/794 (3%)
Query: 57 VSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVT 116
+S+ D +V L L TA K +T+T+++ +P WNE+F F IQS+VKNVLELS+ DED+VT
Sbjct: 40 LSEADPYVILQLSTAPGMKFKTKTLTDTSHPVWNEAFRFLIQSQVKNVLELSIYDEDSVT 99
Query: 117 PDDHLLTVLYDLTKLCFRKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSR 176
DD VLYD++++ K F +PQG EEL+VEFL+EE+ PE L+TN V+V+R
Sbjct: 100 EDDICFKVLYDISEVLPGKLLRKTFSQSPQGEEELDVEFLMEETSDRPENLITNKVIVAR 159
Query: 177 QVSCLEVHAQSRRRRKREKMKDLL---VMVNESFENTQRVRPCLEPCCPTSACFQTAACF 233
++SCL+VH S +D L +++ S+E+TQ T++ F+ F
Sbjct: 160 ELSCLDVHLDSTGSTAVVADQDKLELELVLKGSYEDTQT------SFLGTASAFR----F 209
Query: 234 HYPKYFQSQVHVEVPKSH---WSCGLCCRSRKKGPISQPLDCLSDGQVMTL----PVGES 286
HY ++++ + S W+ G ++ PL L+ G+ +T+ P
Sbjct: 210 HYMAALETELSGRLRSSRSNGWN-----GDNSAGYLTVPLRPLTIGKEVTMDVPAPNAPG 264
Query: 287 YELHMKSTPCPETLDVRLGFSLCPAELEFLQKRKVVVAKALKQVLQLEEDLQEDEVPLIA 346
L +K+ CPE L V LGF+LC E FL +RK VVAKALKQ LQL+ DLQEDEVP++
Sbjct: 265 VRLQLKAEGCPEELAVHLGFNLCAEEQAFLSRRKQVVAKALKQALQLDRDLQEDEVPVVG 324
Query: 347 IMATGGGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSKNLEPA 406
IMATGGG R+MTS+YGHLL LQKL LLDC +Y +G+SG+TWTMA LY DP+WS ++LE
Sbjct: 325 IMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGISGSTWTMAHLYGDPEWSQRDLEGP 384
Query: 407 IFEARRHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDERNECK 466
I AR H+ K KL P++L ++ EL R+++G+ TF D W L++E+ L + + K
Sbjct: 385 IRYAREHLAKSKLEVFSPERLASYRRELELRAEQGHPTTFVDLWALVLESMLHGQVMDQK 444
Query: 467 LSDQRAALSCGQNPLPIYLTINVKD-DVSNQDFREWFEFSPYEVGLQKYGAFIPSELFGS 525
LS QRAAL GQNPLP+YL++NVK+ ++ DF+EW EFSPYEVG KYGAF+P ELFGS
Sbjct: 445 LSGQRAALERGQNPLPLYLSLNVKENNLETLDFKEWVEFSPYEVGFLKYGAFVPPELFGS 504
Query: 526 EFFMGRLVKRIPESRICYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTREKVQDIEDEP 585
EFFMGRL++RIPE RIC++ +WS+IFSLNLLDAW +S E + + ++K + +E EP
Sbjct: 505 EFFMGRLMRRIPEPRICFLEAIWSNIFSLNLLDAWYDLTSSGESWKQHIKDKTRSLEKEP 564
Query: 586 ILPEIPKCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQF 645
+ ++ LE + + PG+ L+ +F+ LT R NFL GLQLH +Y + F
Sbjct: 565 L---TTSGTSSRLEASWLQPGTALAQAFKGFLTGRPLHQRSPNFLQGLQLHQDYCSHKDF 621
Query: 646 SRWKDTVLDGFPNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGSQTK 705
S W D LD P+QLT LCL+D A+F+N+S P + RP R+ DLI+ +Y + +
Sbjct: 622 STWADYQLDSMPSQLTPKEPRLCLVDAAYFINTSSPSMFRPGRRLDLILSFDYSLSAPFE 681
Query: 706 PLKQTCEYCTVQNIPFPKYE-LPDENENLKECYLMENPQEPDAPIVTFFPLINDTFRKYK 764
L+QT YC + +PFP+ E P + +EC+L +P P+API+ FPL+N +F+ +
Sbjct: 682 ALQQTELYCRARGLPFPRVEPSPQDQHQPRECHLFSDPACPEAPILLHFPLVNASFKDHS 741
Query: 765 APGVERSPEELEQGQVDIYGPKTPYATKELTYTEATFDKLVKLSEYNILNNKDTLLQALR 824
APGV+RSP EL+ GQVD+ G PY +TY E F++L++LS+YN+ ++ +LQALR
Sbjct: 742 APGVQRSPAELQGGQVDLTGATCPYTLSNMTYKEEDFERLLRLSDYNVQTSQGAILQALR 801
Query: 825 LAVEKKKRLKGQCP 838
A+ K + L+ + P
Sbjct: 802 TAL-KHRTLEARPP 814
>gi|167860120 phospholipase A2, group IVB [Homo sapiens]
Length = 781
Score = 628 bits (1619), Expect = e-180
Identities = 346/786 (44%), Positives = 476/786 (60%), Gaps = 46/786 (5%)
Query: 57 VSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVT 116
V+ +DC+V+LWLPTA +L+TRT+ N +P WN+SF+F+I ++KNV+EL V D+D VT
Sbjct: 28 VTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVT 87
Query: 117 PDDHLLTVLYDLTKLCFRKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSR 176
DD +L+VL+D L + F L+PQG LEVEF L+ E LV+NGVLV+R
Sbjct: 88 GDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSLADRGEWLVSNGVLVAR 147
Query: 177 QVSCLEVHAQSRRRRKREKMKDLLVMVNESFENTQRVRPCLEPCCPTSACFQTAAC-FHY 235
++SCL V + +K + + LV V S E P A T FH
Sbjct: 148 ELSCLHVQLEETGDQKSSEHRVQLV-VPGSCEG------------PQEASVGTGTFRFHC 194
Query: 236 PKYFQSQVHVEVPKSHWSCGLCCRSRKKGPISQPLDCLSDGQVMTLPVGESYE----LHM 291
P ++ ++ + + + + + PL L GQV+ L S E + +
Sbjct: 195 PACWEQELSIRL-----------QDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVEL 243
Query: 292 KSTPCPETLDVRLGFSLCPAELEFLQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATG 351
K L VRLGF C E FL +RK VVA AL+Q LQL+ DLQEDE+P++AIMATG
Sbjct: 244 KKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATG 303
Query: 352 GGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSKNLEPAIFEAR 411
GG R+MTS+YG L GL++L LLDC SYITG SG+TW +A LY DP+WS K+L +
Sbjct: 304 GGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLK 363
Query: 412 RHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQR 471
V K+KL L P QL+++++EL +R++ GY FT+ W L+ E L DE ++ KLSDQR
Sbjct: 364 TQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQR 423
Query: 472 AALSCGQNPLPIYLTINVK-DDVSNQDFREWFEFSPYEVGLQKYGAFIPSELFGSEFFMG 530
ALS GQNPLPIY +N K ++ +F EW EFSPYEVG KYGAFIPSELFGSEFFMG
Sbjct: 424 EALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMG 483
Query: 531 RLVKRIPESRICYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTREKVQ-DIEDEPIL-- 587
+L+KR+PESRIC++ G+WS++++ NL D+ + +F+ RW R + D E P+L
Sbjct: 484 QLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPLLKI 543
Query: 588 PEIPKCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQFSR 647
E P I E F ++LT R HNFL GL H +Y Q+ FS
Sbjct: 544 EEPPSTAGRIAE------------FFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFST 591
Query: 648 WKDTVLDGFPNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGSQTKPL 707
WK T LDG PNQLT S HLCLLD + +N+S PLL+P R DLI+ L+Y + L
Sbjct: 592 WKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQL 651
Query: 708 KQTCEYCTVQNIPFPKYE-LPDENENLKECYLMENPQEPDAPIVTFFPLINDTFRKYKAP 766
+ +C Q IPFP P+E +EC+ +P P AP V FPL++D+FR+Y AP
Sbjct: 652 QLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAP 711
Query: 767 GVERSPEELEQGQVDIYGPKTPYATKELTYTEATFDKLVKLSEYNILNNKDTLLQALRLA 826
GV R+PEE G+V++ +PY ++TY++ DKL+ L+ YN+ NN++ LL+ALR A
Sbjct: 712 GVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQA 771
Query: 827 VEKKKR 832
V+++++
Sbjct: 772 VQRRRQ 777
>gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]
Length = 1012
Score = 628 bits (1619), Expect = e-180
Identities = 346/786 (44%), Positives = 476/786 (60%), Gaps = 46/786 (5%)
Query: 57 VSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVT 116
V+ +DC+V+LWLPTA +L+TRT+ N +P WN+SF+F+I ++KNV+EL V D+D VT
Sbjct: 259 VTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVT 318
Query: 117 PDDHLLTVLYDLTKLCFRKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSR 176
DD +L+VL+D L + F L+PQG LEVEF L+ E LV+NGVLV+R
Sbjct: 319 GDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSLADRGEWLVSNGVLVAR 378
Query: 177 QVSCLEVHAQSRRRRKREKMKDLLVMVNESFENTQRVRPCLEPCCPTSACFQTAAC-FHY 235
++SCL V + +K + + LV V S E P A T FH
Sbjct: 379 ELSCLHVQLEETGDQKSSEHRVQLV-VPGSCEG------------PQEASVGTGTFRFHC 425
Query: 236 PKYFQSQVHVEVPKSHWSCGLCCRSRKKGPISQPLDCLSDGQVMTLPVGESYE----LHM 291
P ++ ++ + + + + + PL L GQV+ L S E + +
Sbjct: 426 PACWEQELSIRL-----------QDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVEL 474
Query: 292 KSTPCPETLDVRLGFSLCPAELEFLQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATG 351
K L VRLGF C E FL +RK VVA AL+Q LQL+ DLQEDE+P++AIMATG
Sbjct: 475 KKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATG 534
Query: 352 GGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSKNLEPAIFEAR 411
GG R+MTS+YG L GL++L LLDC SYITG SG+TW +A LY DP+WS K+L +
Sbjct: 535 GGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLK 594
Query: 412 RHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQR 471
V K+KL L P QL+++++EL +R++ GY FT+ W L+ E L DE ++ KLSDQR
Sbjct: 595 TQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQR 654
Query: 472 AALSCGQNPLPIYLTINVK-DDVSNQDFREWFEFSPYEVGLQKYGAFIPSELFGSEFFMG 530
ALS GQNPLPIY +N K ++ +F EW EFSPYEVG KYGAFIPSELFGSEFFMG
Sbjct: 655 EALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMG 714
Query: 531 RLVKRIPESRICYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTREKVQ-DIEDEPIL-- 587
+L+KR+PESRIC++ G+WS++++ NL D+ + +F+ RW R + D E P+L
Sbjct: 715 QLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPLLKI 774
Query: 588 PEIPKCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQFSR 647
E P I E F ++LT R HNFL GL H +Y Q+ FS
Sbjct: 775 EEPPSTAGRIAE------------FFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFST 822
Query: 648 WKDTVLDGFPNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGSQTKPL 707
WK T LDG PNQLT S HLCLLD + +N+S PLL+P R DLI+ L+Y + L
Sbjct: 823 WKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQL 882
Query: 708 KQTCEYCTVQNIPFPKYE-LPDENENLKECYLMENPQEPDAPIVTFFPLINDTFRKYKAP 766
+ +C Q IPFP P+E +EC+ +P P AP V FPL++D+FR+Y AP
Sbjct: 883 QLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAP 942
Query: 767 GVERSPEELEQGQVDIYGPKTPYATKELTYTEATFDKLVKLSEYNILNNKDTLLQALRLA 826
GV R+PEE G+V++ +PY ++TY++ DKL+ L+ YN+ NN++ LL+ALR A
Sbjct: 943 GVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQA 1002
Query: 827 VEKKKR 832
V+++++
Sbjct: 1003 VQRRRQ 1008
>gi|67972429 phospholipase A2, group IVF [Homo sapiens]
Length = 849
Score = 574 bits (1479), Expect = e-163
Identities = 333/790 (42%), Positives = 471/790 (59%), Gaps = 28/790 (3%)
Query: 57 VSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVT 116
+S+ DC+V LWLPTAS +TR ++NC +PEWNE+F++QI VKNVLEL++ D+D +
Sbjct: 62 LSKADCYVQLWLPTASPSPAQTRIVANCSDPEWNETFHYQIHGAVKNVLELTLYDKD-IL 120
Query: 117 PDDHLLTVLYDLTKL-CFRKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVS 175
D L +L+DL L C + H FPLN Q +EL+VEF+LE+S P ++TNGVLV+
Sbjct: 121 GSDQLSLLLFDLRSLKCGQPHKHT-FPLNHQDSQELQVEFVLEKSQVPASEVITNGVLVA 179
Query: 176 RQVSCLEVHAQSR----RRRKREKMKDLLVMVNESFENTQRVRPCLEPCCPTSACFQTAA 231
CL + R R+ + L + V ++E Q + L+P PT
Sbjct: 180 HP--CLRIQGTLRGDGTAPREEYGSRQLQLAVPGAYEKPQLLP--LQP--PTEPGLPPTF 233
Query: 232 CFHYPKYFQSQVHVEVPK------SHWSCGLCCRSRKKGPISQPLDCLSDGQV----MTL 281
FH S++HVE+ + S S L ++ K G L L GQ + L
Sbjct: 234 TFHVNPVLSSRLHVELMELLAAVQSGPSAELEAQTSKLGEGGILLSSLPLGQEEQCSVAL 293
Query: 282 PVGESYELHMKSTPCPETLDVRLGFSLCPAELEFLQKRKVVVAKALKQVLQLEEDLQEDE 341
G+ L MK LD+RLGF L E EFL +RK VV+KAL+QVL L E L +
Sbjct: 294 GEGQEVALSMKVEMSSGDLDLRLGFDLSDGEQEFLDRRKQVVSKALQQVLGLSEALDSGQ 353
Query: 342 VPLIAIMATGGGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSK 401
VP++A++ +GGGTR+M+S+YG L GLQ+L LLD +Y++G+SG+TW ++TLYRDP WS
Sbjct: 354 VPVVAVLGSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYRDPAWSQV 413
Query: 402 NLEPAIFEARRHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDE 461
L+ I A+ HV K+ +L ++L+ + +EL R + G+ V+ D WGLL+E L E
Sbjct: 414 ALQGPIERAQVHVCSSKMGALSTERLQYYTQELGVRERSGHSVSLIDLWGLLVEYLLYQE 473
Query: 462 RNECKLSDQRAALSCGQNPLPIYLTINVKDDVSNQDFREWFEFSPYEVGLQKYGAFIPSE 521
N KLSDQ+ A+ GQNP PIY ++NV+ ++S +DF EW EF+PYEVG KYGA++P+E
Sbjct: 474 ENPAKLSDQQEAVRQGQNPYPIYTSVNVRTNLSGEDFAEWCEFTPYEVGFPKYGAYVPTE 533
Query: 522 LFGSEFFMGRLVKRIPESRICYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTREKVQDI 581
LFGSE FMGRL++ PE RICY+ G+W S F+ +L + + + S F W R V +I
Sbjct: 534 LFGSELFMGRLLQLQPEPRICYLQGMWGSAFATSLDEIFLKTAGSGLSFLEWYRGSV-NI 592
Query: 582 EDEPILPEIPKCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQ 641
D+ P++ + + L T ++ P S + +I T R ++ NF GL LH +Y+
Sbjct: 593 TDDCQKPQLH--NPSRLRTRLLTPQGPFSQAVLDIFTSRFTSAQSFNFTRGLCLHKDYVA 650
Query: 642 NGQFSRWKDTVLDGFPNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAG 701
+F WKDT D FPNQLT + L L+D F +NS +P L P+R DLI+ +Y
Sbjct: 651 GREFVAWKDTHPDAFPNQLTPMRDCLYLVDGGFAINSPFPLALLPQRAVDLILSFDYSLE 710
Query: 702 SQTKPLKQTCEYCTVQNIPFPKYEL-PDENENLKECYLMENPQEPDAPIVTFFPLINDTF 760
+ + LK T +YC + IPFP E+ P++ E +ECYL ++P +PIV FPL+N TF
Sbjct: 711 APFEVLKMTEKYCLDRGIPFPSIEVGPEDVEEARECYLFAKAEDPRSPIVLHFPLVNRTF 770
Query: 761 RKYKAPGVER-SPEELEQGQVDIYGPKTPYATKELTYTEATFDKLVKLSEYNILNNKDTL 819
R + APGVER + EE G I P TPY TY F +LV LS YN+LNN +TL
Sbjct: 771 RTHLAPGVERQTAEEKAFGDFVINRPDTPYGMMNFTYEPQDFYRLVALSRYNVLNNVETL 830
Query: 820 LQALRLAVEK 829
AL+LA+++
Sbjct: 831 KCALQLALDR 840
>gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens]
Length = 749
Score = 291 bits (746), Expect = 1e-78
Identities = 192/597 (32%), Positives = 310/597 (51%), Gaps = 50/597 (8%)
Query: 288 ELHMKSTPCPETLDVRLGFSLCPAELEFLQKRKVVVAKALKQVL--QLEEDLQED-EVPL 344
E+ ++ CP D+R +LC E F Q+RK + +++K++L + E L +VP+
Sbjct: 133 EMSLEVCSCP---DLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPV 189
Query: 345 IAIMATGGGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSKNLE 404
+AI+ +GGG R+M G + L + +LDCA+Y+ GLSG+TW M+TLY PD+ K E
Sbjct: 190 VAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPE 249
Query: 405 PAIFEARRHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDERNE 464
E ++V + L L P +++++ E L ++ G VTFTD +G+LI L R
Sbjct: 250 EINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMN 309
Query: 465 CKLSDQRAALSCGQNPLPIYLTINVKDDVSNQDFREWFEFSPYEVGLQKYGAFIPSELFG 524
LS + ++ Q PLP++ ++VK DVS F +W EFSPYE+G+ KYG F+ +LFG
Sbjct: 310 TTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFG 369
Query: 525 SEFFMGRLVKRIPESRICYMLGLWSSIFS------LNLLDAWNLSHTSEEFFHRWTREKV 578
S+FFMG +VK+ E+ + +++G+W S FS L + + + T EE T + +
Sbjct: 370 SKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELENITTKHI 429
Query: 579 -----QDIEDEPILPEIPKCDANILETTVVIPGSWLSNSFREIL-------THRSFVSEF 626
D +DE P+ + + + SW+ ++ T +
Sbjct: 430 VSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRAGKV 489
Query: 627 HNFLSGLQLHTNYLQN-----GQFSRWKDTVLDGF---PNQ-------LTESANHLCLLD 671
HNF+ GL L+T+Y + + D LD P++ L + + ++D
Sbjct: 490 HNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVD 549
Query: 672 TAFFVNSSYPPLLRPERKADLIIHLNYCA--GSQTKPLKQTC---EYCTVQNIPFPKYE- 725
+ N YP +LRP+R DLII ++ A + P K+ ++ + +PFPK +
Sbjct: 550 SGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDP 609
Query: 726 LPDENENLKECYLM--ENP-QEPDAPIVTFFPLINDTFRKYKAPGVER-SPEELEQGQVD 781
+ E LKECY+ +NP E D P + F L N FRKYKAPGV R + EE E D
Sbjct: 610 YVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYKAPGVPRETEEEKEIADFD 669
Query: 782 IY-GPKTPYATKELTYTEATFDKLVKLSEYNILNNKDTLLQALRLAVEKKKRLKGQC 837
I+ P++P++T Y F +L L +N LNN D + +A+ ++E +++ +C
Sbjct: 670 IFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRRQNPSRC 726
Score = 57.0 bits (136), Expect = 7e-08
Identities = 43/140 (30%), Positives = 69/140 (49%), Gaps = 9/140 (6%)
Query: 61 DCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDH 120
D +V L++ T + RTR +N NP WNE+F F + +NVLE+++ D + V D+
Sbjct: 43 DPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVM-DET 101
Query: 121 LLTVLYDLTKLCFRKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSRQVSC 180
L T + ++ + +K V F N + E+ +E LE P L + L ++
Sbjct: 102 LGTATFTVSSMKVGEKKEVPFIFNQ--VTEMVLEMSLEVCSCP--DLRFSMALCDQE--- 154
Query: 181 LEVHAQSRRRRKREKMKDLL 200
+ Q R+ RE MK LL
Sbjct: 155 -KTFRQQRKEHIRESMKKLL 173
>gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens]
Length = 527
Score = 154 bits (389), Expect = 3e-37
Identities = 141/546 (25%), Positives = 237/546 (43%), Gaps = 81/546 (14%)
Query: 316 LQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATGGGTRSMTSMYGHLLGLQKLNLLDC 375
+++R++ V KALK++ ++ DE P++A++ +GGG R+ + G L +++ LLD
Sbjct: 20 VERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLLDA 74
Query: 376 ASYITGLSGATWTMATLY-RDPDWSSKNLEPAIFEARRHVVKDKLPSLFPDQLRKFQEEL 434
+Y+ G+SG+TW +++LY D D EA +K + D + Q+ +
Sbjct: 75 VTYLAGVSGSTWAISSLYTNDGD----------MEALEADLKHRFTRQEWDLAKSLQKTI 124
Query: 435 RQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQRAALSCGQNPLPIYLTINVKDDVS 494
+ E Y + TDFW ++ + E E LS+ + + G P PI+ I+ S
Sbjct: 125 QAARSENY--SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPS 182
Query: 495 NQDFR---EWFEFSPYEVGLQKYGAFIPSELFGSEFFMGRLVKRIPESRICYMLGLWSS- 550
Q+ R WFEF+P+ G GAF+ FGS+F GRLV+ PE + ++ GLW S
Sbjct: 183 WQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSA 242
Query: 551 --------------IFSLNLLDAW-----NLSHTSEEFFHRWTREKVQDIEDEPILPEIP 591
+ +L L W N F R R + + P P
Sbjct: 243 LGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHP----PP 298
Query: 592 KCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQF--SRWK 649
+ + E T + L N R L + E L ++++ S+W+
Sbjct: 299 EDEGGEPEHTWLT--EMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWE 356
Query: 650 DTVLDGF-------PNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGS 702
F +++ S HL L+D +N+ +P +L P R+ LI+ ++ AG
Sbjct: 357 WGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGD 416
Query: 703 QTKPLKQTCEYCTVQNIPFPKY---ELPDENENLKECYLMENPQEPDAPIVTFFPLINDT 759
+ ++ T +YC IPFP+ EL ++ CY+++ P+V FPL N
Sbjct: 417 PFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKG---ETGPVVMHFPLFN-- 471
Query: 760 FRKYKAPGVERSPEELEQGQVDIYGPKTPYATKEL--TYTEATFDKLVKLSEYNILNNKD 817
++ DI Y T +L TYT L+ L++ N+ NK
Sbjct: 472 ---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKK 516
Query: 818 TLLQAL 823
+L+ L
Sbjct: 517 KILREL 522
>gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Homo
sapiens]
Length = 551
Score = 154 bits (389), Expect = 3e-37
Identities = 141/546 (25%), Positives = 237/546 (43%), Gaps = 81/546 (14%)
Query: 316 LQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATGGGTRSMTSMYGHLLGLQKLNLLDC 375
+++R++ V KALK++ ++ DE P++A++ +GGG R+ + G L +++ LLD
Sbjct: 30 VERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLLDA 84
Query: 376 ASYITGLSGATWTMATLY-RDPDWSSKNLEPAIFEARRHVVKDKLPSLFPDQLRKFQEEL 434
+Y+ G+SG+TW +++LY D D EA +K + D + Q+ +
Sbjct: 85 VTYLAGVSGSTWAISSLYTNDGD----------MEALEADLKHRFTRQEWDLAKSLQKTI 134
Query: 435 RQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQRAALSCGQNPLPIYLTINVKDDVS 494
+ E Y + TDFW ++ + E E LS+ + + G P PI+ I+ S
Sbjct: 135 QAARSENY--SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPS 192
Query: 495 NQDFR---EWFEFSPYEVGLQKYGAFIPSELFGSEFFMGRLVKRIPESRICYMLGLWSS- 550
Q+ R WFEF+P+ G GAF+ FGS+F GRLV+ PE + ++ GLW S
Sbjct: 193 WQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSA 252
Query: 551 --------------IFSLNLLDAW-----NLSHTSEEFFHRWTREKVQDIEDEPILPEIP 591
+ +L L W N F R R + + P P
Sbjct: 253 LGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHP----PP 308
Query: 592 KCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQF--SRWK 649
+ + E T + L N R L + E L ++++ S+W+
Sbjct: 309 EDEGGEPEHTWLT--EMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWE 366
Query: 650 DTVLDGF-------PNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGS 702
F +++ S HL L+D +N+ +P +L P R+ LI+ ++ AG
Sbjct: 367 WGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGD 426
Query: 703 QTKPLKQTCEYCTVQNIPFPKY---ELPDENENLKECYLMENPQEPDAPIVTFFPLINDT 759
+ ++ T +YC IPFP+ EL ++ CY+++ P+V FPL N
Sbjct: 427 PFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKG---ETGPVVMHFPLFN-- 481
Query: 760 FRKYKAPGVERSPEELEQGQVDIYGPKTPYATKEL--TYTEATFDKLVKLSEYNILNNKD 817
++ DI Y T +L TYT L+ L++ N+ NK
Sbjct: 482 ---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKK 526
Query: 818 TLLQAL 823
+L+ L
Sbjct: 527 KILREL 532
>gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Homo
sapiens]
Length = 541
Score = 154 bits (389), Expect = 3e-37
Identities = 141/546 (25%), Positives = 237/546 (43%), Gaps = 81/546 (14%)
Query: 316 LQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATGGGTRSMTSMYGHLLGLQKLNLLDC 375
+++R++ V KALK++ ++ DE P++A++ +GGG R+ + G L +++ LLD
Sbjct: 20 VERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLLDA 74
Query: 376 ASYITGLSGATWTMATLY-RDPDWSSKNLEPAIFEARRHVVKDKLPSLFPDQLRKFQEEL 434
+Y+ G+SG+TW +++LY D D EA +K + D + Q+ +
Sbjct: 75 VTYLAGVSGSTWAISSLYTNDGD----------MEALEADLKHRFTRQEWDLAKSLQKTI 124
Query: 435 RQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQRAALSCGQNPLPIYLTINVKDDVS 494
+ E Y + TDFW ++ + E E LS+ + + G P PI+ I+ S
Sbjct: 125 QAARSENY--SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPS 182
Query: 495 NQDFR---EWFEFSPYEVGLQKYGAFIPSELFGSEFFMGRLVKRIPESRICYMLGLWSS- 550
Q+ R WFEF+P+ G GAF+ FGS+F GRLV+ PE + ++ GLW S
Sbjct: 183 WQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSA 242
Query: 551 --------------IFSLNLLDAW-----NLSHTSEEFFHRWTREKVQDIEDEPILPEIP 591
+ +L L W N F R R + + P P
Sbjct: 243 LGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHP----PP 298
Query: 592 KCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQF--SRWK 649
+ + E T + L N R L + E L ++++ S+W+
Sbjct: 299 EDEGGEPEHTWLT--EMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWE 356
Query: 650 DTVLDGF-------PNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGS 702
F +++ S HL L+D +N+ +P +L P R+ LI+ ++ AG
Sbjct: 357 WGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGD 416
Query: 703 QTKPLKQTCEYCTVQNIPFPKY---ELPDENENLKECYLMENPQEPDAPIVTFFPLINDT 759
+ ++ T +YC IPFP+ EL ++ CY+++ P+V FPL N
Sbjct: 417 PFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKG---ETGPVVMHFPLFN-- 471
Query: 760 FRKYKAPGVERSPEELEQGQVDIYGPKTPYATKEL--TYTEATFDKLVKLSEYNILNNKD 817
++ DI Y T +L TYT L+ L++ N+ NK
Sbjct: 472 ---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKK 516
Query: 818 TLLQAL 823
+L+ L
Sbjct: 517 KILREL 522
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 45.4 bits (106), Expect = 2e-04
Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 7/77 (9%)
Query: 68 LPTASQ-KKLRTRTISNCPNPEWNES---FNFQIQSRVKNVLELSVCDEDTVTPDDHLLT 123
LP AS+ KLRT+T+ N NP WNE+ + + ++ L +SVCDED ++ +
Sbjct: 171 LPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGE 230
Query: 124 VLYDLTKLCFRKKTHVK 140
L KL K H K
Sbjct: 231 TRVPLKKL---KPNHTK 244
>gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Homo
sapiens]
Length = 823
Score = 43.5 bits (101), Expect = 8e-04
Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Query: 58 SQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTP 117
S T+ FV L L ++ +++T+ NP+W E F+F S +L++ V +D
Sbjct: 372 SMTEMFVQLKL---GDQRYKSKTLCKSANPQWQEQFDFHYFSDRMGILDIEVWGKDNKKH 428
Query: 118 DDHLLTVLYDLTKLCFRKKTHVKFPLN 144
++ L T D++ L ++ ++ PL+
Sbjct: 429 EERLGTCKVDISALPLKQANCLELPLD 455
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 75 KLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKL 131
+L+T T+ NPEWN+ F F I+ + +VLE++V DED P D L V L +
Sbjct: 542 RLQTHTVYKNLNPEWNKVFTFPIKD-IHDVLEVTVFDEDGDKPPDFLGKVAIPLLSI 597
>gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Homo
sapiens]
Length = 878
Score = 43.5 bits (101), Expect = 8e-04
Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Query: 58 SQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTP 117
S T+ FV L L ++ +++T+ NP+W E F+F S +L++ V +D
Sbjct: 372 SMTEMFVQLKL---GDQRYKSKTLCKSANPQWQEQFDFHYFSDRMGILDIEVWGKDNKKH 428
Query: 118 DDHLLTVLYDLTKLCFRKKTHVKFPLN 144
++ L T D++ L ++ ++ PL+
Sbjct: 429 EERLGTCKVDISALPLKQANCLELPLD 455
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 75 KLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKL 131
+L+T T+ NPEWN+ F F I+ + +VLE++V DED P D L V L +
Sbjct: 542 RLQTHTVYKNLNPEWNKVFTFPIKD-IHDVLEVTVFDEDGDKPPDFLGKVAIPLLSI 597
>gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]
Length = 671
Score = 43.5 bits (101), Expect = 8e-04
Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 26/195 (13%)
Query: 4 KCITEPVGIELAPCLQAPSVPETDL-----KGVVQARGGGASVLEKPREGFKRAEQVPVS 58
KC T + + + PS+ TD + +QA ++ R+ P
Sbjct: 131 KCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNG 190
Query: 59 QTDCFVSLWL--PTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKN-VLELSVCDEDTV 115
+D +V L L S+ K +T+TI NPEWNE+F FQ++ K+ L + + D D
Sbjct: 191 LSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLT 250
Query: 116 TPDDHLLTVLYDLTK------------LCFRKKTHVKFPLNPQGM---EELEVEF---LL 157
+ +D + ++ + +++ L + + P+ P+G EEL +F +
Sbjct: 251 SRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKI 310
Query: 158 EESPSPPETLVTNGV 172
+ PE TN V
Sbjct: 311 SQGTKVPEEKTTNTV 325
>gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]
Length = 673
Score = 43.5 bits (101), Expect = 8e-04
Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 26/195 (13%)
Query: 4 KCITEPVGIELAPCLQAPSVPETDL-----KGVVQARGGGASVLEKPREGFKRAEQVPVS 58
KC T + + + PS+ TD + +QA ++ R+ P
Sbjct: 131 KCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNG 190
Query: 59 QTDCFVSLWL--PTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKN-VLELSVCDEDTV 115
+D +V L L S+ K +T+TI NPEWNE+F FQ++ K+ L + + D D
Sbjct: 191 LSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLT 250
Query: 116 TPDDHLLTVLYDLTK------------LCFRKKTHVKFPLNPQGM---EELEVEF---LL 157
+ +D + ++ + +++ L + + P+ P+G EEL +F +
Sbjct: 251 SRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKI 310
Query: 158 EESPSPPETLVTNGV 172
+ PE TN V
Sbjct: 311 SQGTKVPEEKTTNTV 325
>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
sapiens]
Length = 778
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 14/124 (11%)
Query: 74 KKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKLCF 133
+K +++ + NP+W E F+F + V++++ D+D DD + DL+ L
Sbjct: 281 QKYKSKIMPKTLNPQWREQFDFHLYEERGGVIDITAWDKDAGKRDDFIGRCQVDLSALS- 339
Query: 134 RKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSRQVSCLEVHAQSRRRRKR 193
R++TH ++E LEE LVT + +S L V++ ++ +
Sbjct: 340 REQTH-------------KLELQLEEGEGHLVLLVTLTASATVSISDLSVNSLEDQKERE 386
Query: 194 EKMK 197
E +K
Sbjct: 387 EILK 390
Score = 41.6 bits (96), Expect = 0.003
Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 47 EGFKRAEQVPVSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLE 106
EG A+ S C V L + +L T T+ NPEWN+ F F I+ + +VLE
Sbjct: 415 EGLMAADVTGKSDPFCVVEL-----NNDRLLTHTVYKNLNPEWNKVFTFNIKD-IHSVLE 468
Query: 107 LSVCDEDTVTPDDHLLTVLYDLTKL 131
++V DED D L V L +
Sbjct: 469 VTVYDEDRDRSADFLGKVAIPLLSI 493
>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
sapiens]
Length = 999
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 14/124 (11%)
Query: 74 KKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKLCF 133
+K +++ + NP+W E F+F + V++++ D+D DD + DL+ L
Sbjct: 502 QKYKSKIMPKTLNPQWREQFDFHLYEERGGVIDITAWDKDAGKRDDFIGRCQVDLSALS- 560
Query: 134 RKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSRQVSCLEVHAQSRRRRKR 193
R++TH ++E LEE LVT + +S L V++ ++ +
Sbjct: 561 REQTH-------------KLELQLEEGEGHLVLLVTLTASATVSISDLSVNSLEDQKERE 607
Query: 194 EKMK 197
E +K
Sbjct: 608 EILK 611
Score = 41.6 bits (96), Expect = 0.003
Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 47 EGFKRAEQVPVSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLE 106
EG A+ S C V L + +L T T+ NPEWN+ F F I+ + +VLE
Sbjct: 636 EGLMAADVTGKSDPFCVVEL-----NNDRLLTHTVYKNLNPEWNKVFTFNIKD-IHSVLE 689
Query: 107 LSVCDEDTVTPDDHLLTVLYDLTKL 131
++V DED D L V L +
Sbjct: 690 VTVYDEDRDRSADFLGKVAIPLLSI 714
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 4/68 (5%)
Query: 68 LPTASQK-KLRTRTISNCPNPEWNESFNFQ---IQSRVKNVLELSVCDEDTVTPDDHLLT 123
LP AS+ KLRT+T+ N NP WNE+ + + + L +SVCDED ++ +
Sbjct: 437 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 496
Query: 124 VLYDLTKL 131
+ L KL
Sbjct: 497 TRFSLKKL 504
Score = 35.4 bits (80), Expect = 0.22
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 60 TDCFVSLWLPTASQKKLRTRTI--SNCPNPEWNESFNFQIQ--SRVKNVLELSVCDEDTV 115
+D FV LWL KK + +T NPE+NE F + I+ K L++SV D D
Sbjct: 586 SDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIG 645
Query: 116 TPDDHL 121
+D++
Sbjct: 646 KSNDYI 651
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 4/68 (5%)
Query: 68 LPTASQK-KLRTRTISNCPNPEWNESFNFQ---IQSRVKNVLELSVCDEDTVTPDDHLLT 123
LP AS+ KLRT+T+ N NP WNE+ + + + L +SVCDED ++ +
Sbjct: 433 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 492
Query: 124 VLYDLTKL 131
+ L KL
Sbjct: 493 TRFSLKKL 500
Score = 35.4 bits (80), Expect = 0.22
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 60 TDCFVSLWLPTASQKKLRTRTI--SNCPNPEWNESFNFQIQ--SRVKNVLELSVCDEDTV 115
+D FV LWL KK + +T NPE+NE F + I+ K L++SV D D
Sbjct: 582 SDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIG 641
Query: 116 TPDDHL 121
+D++
Sbjct: 642 KSNDYI 647
>gi|227496504 multiple C2 domains, transmembrane 2 isoform 3 [Homo
sapiens]
Length = 306
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 75 KLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKL 131
+L+T T+ NPEWN+ F F I+ + +VLE++V DED P D L V L +
Sbjct: 130 RLQTHTVYKNLNPEWNKVFTFPIKD-IHDVLEVTVFDEDGDKPPDFLGKVAIPLLSI 185
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 41.2 bits (95), Expect = 0.004
Identities = 24/79 (30%), Positives = 46/79 (58%), Gaps = 3/79 (3%)
Query: 56 PVSQTDCFVSLWL--PTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKN-VLELSVCDE 112
P +D +V L L ++ K +T+TI + NP+WNESF F+++ K+ L + + D
Sbjct: 188 PNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDW 247
Query: 113 DTVTPDDHLLTVLYDLTKL 131
D T +D + ++ + +++L
Sbjct: 248 DRTTRNDFMGSLSFGVSEL 266
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 41.2 bits (95), Expect = 0.004
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 3/79 (3%)
Query: 71 ASQKKLRTRTISNCPNPEWNESFNFQ---IQSRVKNVLELSVCDEDTVTPDDHLLTVLYD 127
+++ K RT+ + NPEWN++ ++ ++ K LE++V D D + +D L VL D
Sbjct: 4750 SAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLID 4809
Query: 128 LTKLCFRKKTHVKFPLNPQ 146
L+ T +PL Q
Sbjct: 4810 LSSTSHLDNTPRWYPLKEQ 4828
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 41.2 bits (95), Expect = 0.004
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 3/79 (3%)
Query: 71 ASQKKLRTRTISNCPNPEWNESFNFQ---IQSRVKNVLELSVCDEDTVTPDDHLLTVLYD 127
+++ K RT+ + NPEWN++ ++ ++ K LE++V D D + +D L VL D
Sbjct: 4750 SAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLID 4809
Query: 128 LTKLCFRKKTHVKFPLNPQ 146
L+ T +PL Q
Sbjct: 4810 LSSTSHLDNTPRWYPLKEQ 4828
>gi|21361472 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 3 [Homo sapiens]
Length = 955
Score = 40.8 bits (94), Expect = 0.005
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 30 GVVQARGGGASVLEKPREGFKRAEQVPVSQTDCFVSLWLPTASQKK----LRTRTISNCP 85
G+ + G + K G A++ +D +V L L A + + ++T+TI
Sbjct: 11 GLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTL 70
Query: 86 NPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKL 131
NP+WNE F F++ +L V DE+ +T DD L V L+ L
Sbjct: 71 NPKWNEEFYFRVNPSNHRLL-FEVFDENRLTRDDFLGQVDVPLSHL 115
>gi|222352086 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 1 [Homo sapiens]
Length = 975
Score = 40.8 bits (94), Expect = 0.005
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 30 GVVQARGGGASVLEKPREGFKRAEQVPVSQTDCFVSLWLPTASQKK----LRTRTISNCP 85
G+ + G + K G A++ +D +V L L A + + ++T+TI
Sbjct: 11 GLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTL 70
Query: 86 NPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKL 131
NP+WNE F F++ +L V DE+ +T DD L V L+ L
Sbjct: 71 NPKWNEEFYFRVNPSNHRLL-FEVFDENRLTRDDFLGQVDVPLSHL 115
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 40.4 bits (93), Expect = 0.007
Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
Query: 61 DCFVSLWLPTASQK--KLRTRTISNCPNPEWNESFNFQ---IQSRVKNVLELSVCDEDTV 115
D +V L L + K KL+T+T N NP WNE + VL ++VCDED +
Sbjct: 126 DPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKL 185
Query: 116 TPDDHLLTVLYDLTKLCFRKKTHVKFPLNPQ 146
+ ++ + + L +L +K H L Q
Sbjct: 186 SHNEFIGEIRVPLRRLKPSQKKHFNICLERQ 216
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 40.0 bits (92), Expect = 0.009
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 7/88 (7%)
Query: 51 RAEQVPVSQ----TDCFVSLWLPTASQKKLRTRTISNCPNPEWNESF---NFQIQSRVKN 103
+A+++P +D FV ++L + KL T+ NP WNE+F F + V+
Sbjct: 158 KAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQR 217
Query: 104 VLELSVCDEDTVTPDDHLLTVLYDLTKL 131
+L L V D D + +D + V L K+
Sbjct: 218 ILYLQVLDYDRFSRNDPIGEVSIPLNKV 245
>gi|222352090 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 5 [Homo sapiens]
Length = 947
Score = 39.7 bits (91), Expect = 0.012
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 5/88 (5%)
Query: 48 GFKRAEQVPVSQTDCFVSLWLPTASQKK----LRTRTISNCPNPEWNESFNFQIQSRVKN 103
G A++ +D +V L L A + + ++T+TI NP+WNE F F++
Sbjct: 21 GIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHR 80
Query: 104 VLELSVCDEDTVTPDDHLLTVLYDLTKL 131
+L V DE+ +T DD L V L+ L
Sbjct: 81 LL-FEVFDENRLTRDDFLGQVDVPLSHL 107
>gi|222352088 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 4 [Homo sapiens]
Length = 967
Score = 39.7 bits (91), Expect = 0.012
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 5/88 (5%)
Query: 48 GFKRAEQVPVSQTDCFVSLWLPTASQKK----LRTRTISNCPNPEWNESFNFQIQSRVKN 103
G A++ +D +V L L A + + ++T+TI NP+WNE F F++
Sbjct: 21 GIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHR 80
Query: 104 VLELSVCDEDTVTPDDHLLTVLYDLTKL 131
+L V DE+ +T DD L V L+ L
Sbjct: 81 LL-FEVFDENRLTRDDFLGQVDVPLSHL 107
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 39.7 bits (91), Expect = 0.012
Identities = 19/44 (43%), Positives = 28/44 (63%)
Query: 78 TRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDHL 121
TRTI + NP+WN + F I+ ++VL L++ D D +PDD L
Sbjct: 1578 TRTIQDTLNPKWNFNCQFFIKDLYQDVLCLTLFDRDQFSPDDFL 1621
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 39.7 bits (91), Expect = 0.012
Identities = 19/44 (43%), Positives = 28/44 (63%)
Query: 78 TRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVTPDDHL 121
TRTI + NP+WN + F I+ ++VL L++ D D +PDD L
Sbjct: 1605 TRTIQDTLNPKWNFNCQFFIKDLYQDVLCLTLFDRDQFSPDDFL 1648
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,253,674
Number of Sequences: 37866
Number of extensions: 1702974
Number of successful extensions: 4665
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 4525
Number of HSP's gapped (non-prelim): 159
length of query: 839
length of database: 18,247,518
effective HSP length: 111
effective length of query: 728
effective length of database: 14,044,392
effective search space: 10224317376
effective search space used: 10224317376
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.