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Search of human proteins with 122937420
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937420 plasma kallikrein-like protein 4 [Homo sapiens]
(395 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937420 plasma kallikrein-like protein 4 [Homo sapiens] 811 0.0
gi|110578663 hypothetical protein LOC203074 [Homo sapiens] 100 2e-21
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 86 4e-17
gi|32698940 transmembrane protease, serine 12 [Homo sapiens] 84 2e-16
gi|4503627 coagulation factor XI precursor [Homo sapiens] 82 6e-16
gi|148806900 epidermis-specific serine protease-like protein [Ho... 82 6e-16
gi|4506153 prostasin preproprotein [Homo sapiens] 82 8e-16
gi|34098976 marapsin 2 [Homo sapiens] 82 8e-16
gi|4503137 chymotrypsin-like [Homo sapiens] 82 8e-16
gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo s... 80 2e-15
gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo ... 80 2e-15
gi|148613878 acrosin precursor [Homo sapiens] 80 4e-15
gi|15559207 elastase 2A preproprotein [Homo sapiens] 79 5e-15
gi|13994276 marapsin [Homo sapiens] 79 5e-15
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 78 2e-14
gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 76 6e-14
gi|58331211 elastase 2B preproprotein [Homo sapiens] 75 8e-14
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 75 8e-14
gi|4503625 coagulation factor X preproprotein [Homo sapiens] 74 2e-13
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 73 4e-13
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 73 4e-13
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 73 4e-13
gi|29244926 corin [Homo sapiens] 73 4e-13
gi|11545839 protease, serine, 22 [Homo sapiens] 73 5e-13
gi|118498341 chymotrypsin B1 [Homo sapiens] 71 2e-12
gi|110815798 ovochymase 1 [Homo sapiens] 71 2e-12
gi|223942069 enterokinase precursor [Homo sapiens] 70 3e-12
gi|118498350 chymotrypsin B2 [Homo sapiens] 69 7e-12
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 69 7e-12
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa... 69 1e-11
>gi|122937420 plasma kallikrein-like protein 4 [Homo sapiens]
Length = 395
Score = 811 bits (2095), Expect = 0.0
Identities = 395/395 (100%), Positives = 395/395 (100%)
Query: 1 MVSAAGLSGDGKMRGVLLVLLGLLYSSTSCGVQKASVFYGPDPKEGLVSSMEFPWVVSLQ 60
MVSAAGLSGDGKMRGVLLVLLGLLYSSTSCGVQKASVFYGPDPKEGLVSSMEFPWVVSLQ
Sbjct: 1 MVSAAGLSGDGKMRGVLLVLLGLLYSSTSCGVQKASVFYGPDPKEGLVSSMEFPWVVSLQ 60
Query: 61 DSQYTHLAFGCILSEFWVLSIASAIQNRKDIVVIVGISNMDPSKIAHTEYPVNTIIIHED 120
DSQYTHLAFGCILSEFWVLSIASAIQNRKDIVVIVGISNMDPSKIAHTEYPVNTIIIHED
Sbjct: 61 DSQYTHLAFGCILSEFWVLSIASAIQNRKDIVVIVGISNMDPSKIAHTEYPVNTIIIHED 120
Query: 121 FDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMT 180
FDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMT
Sbjct: 121 FDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMT 180
Query: 181 MSVLRKIFVKDLDMCPLYKLQKTECGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGV 240
MSVLRKIFVKDLDMCPLYKLQKTECGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGV
Sbjct: 181 MSVLRKIFVKDLDMCPLYKLQKTECGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGV 240
Query: 241 LNFGGETCPGLFLYTKVEDYSKWITSKAERAGPPLSSLHHWEKLISFSHHGPNATMTQKT 300
LNFGGETCPGLFLYTKVEDYSKWITSKAERAGPPLSSLHHWEKLISFSHHGPNATMTQKT
Sbjct: 241 LNFGGETCPGLFLYTKVEDYSKWITSKAERAGPPLSSLHHWEKLISFSHHGPNATMTQKT 300
Query: 301 YSDSELGHVGSYLQGQRRTITHSRLGNSSRDSLDVREKDVKESGRSPEASVQPLYYDYYG 360
YSDSELGHVGSYLQGQRRTITHSRLGNSSRDSLDVREKDVKESGRSPEASVQPLYYDYYG
Sbjct: 301 YSDSELGHVGSYLQGQRRTITHSRLGNSSRDSLDVREKDVKESGRSPEASVQPLYYDYYG 360
Query: 361 GEVGEGRIFAGQNRLYQPEEIILVSFVLVFFCSSI 395
GEVGEGRIFAGQNRLYQPEEIILVSFVLVFFCSSI
Sbjct: 361 GEVGEGRIFAGQNRLYQPEEIILVSFVLVFFCSSI 395
>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
Length = 352
Score = 100 bits (249), Expect = 2e-21
Identities = 69/238 (28%), Positives = 122/238 (51%), Gaps = 19/238 (7%)
Query: 52 EFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQNRK----DIVVIVGISNMDPSKIAH 107
EFPW VS+Q ++ G IL+++W+L+ A + + + ++ V++G +++ +
Sbjct: 78 EFPWQVSIQ-ARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEI 136
Query: 108 TEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVS 167
E V +II+H+DF +M N+IALL + + +L IC + P + CWV+
Sbjct: 137 KE--VASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQP--GPATWRECWVA 192
Query: 168 GWNPTSATGNHMTMSVLRK--IFVKDLDMCPLY--KLQKTECGSHTKEETKTACLGDPGS 223
GW T+A + + L K + + D + C KL K + K E+ AC GD G
Sbjct: 193 GWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKNESYDACKGDSGG 252
Query: 224 PMMCQLQQFDLWVLRGVLNFG---GE-TCPGLFLYTKVEDYSKWITSKAERAGPPLSS 277
P++C + + W G++++G GE PG +YT + +Y+ WI + G P ++
Sbjct: 253 PLVCTPEPGEKWYQVGIISWGKSCGEKNTPG--IYTSLVNYNLWIEKVTQLEGRPFNA 308
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 86.3 bits (212), Expect = 4e-17
Identities = 70/235 (29%), Positives = 115/235 (48%), Gaps = 26/235 (11%)
Query: 52 EFPWVVSLQD--SQYTHLAFGCILSEFWVLSIASAIQNR--KDIVVIV-GISNMDPSKIA 106
E+PW VSLQ + HL G ++ WVL+ A +D+ I GI N+
Sbjct: 401 EWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKD 460
Query: 107 HTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWV 166
+ IIIH+++ + +++IAL+K +++ + IC + T + NCWV
Sbjct: 461 TPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG-DTSTIYTNCWV 519
Query: 167 SGWNPTSATGNHMTMSVLRKIFVKDL--DMCPL----YKL-QKTECGSHTKEETKTACLG 219
+GW + G ++L+K+ + + + C YK+ Q+ C + KE K AC G
Sbjct: 520 TGWGFSKEKGE--IQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY-KEGGKDACKG 576
Query: 220 DPGSPMMCQLQQFDLWVLRGVLNFGGETC-----PGLFLYTKVEDYSKWITSKAE 269
D G P++C + +W L G+ ++ GE C PG +YTKV +Y WI K +
Sbjct: 577 DSGGPLVC--KHNGMWRLVGITSW-GEGCARREQPG--VYTKVAEYMDWILEKTQ 626
>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
Length = 348
Score = 84.3 bits (207), Expect = 2e-16
Identities = 59/229 (25%), Positives = 105/229 (45%), Gaps = 19/229 (8%)
Query: 53 FPWVVSLQDSQ---YTHLAFGCILSEFWVLSIASAIQNRKDIVV---IVGISNMDPSKIA 106
+PWVVSLQ H+ G ++ E WVL+ A ++ D ++ ++G +N+ +
Sbjct: 89 WPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIH-GRYP 147
Query: 107 HTE-YPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCW 165
HT+ + IIIH +F S N+IAL A+ + + +Q IC + C+
Sbjct: 148 HTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCF 207
Query: 166 VSGWNPTSATGNHMTMSVLRKIFVKDLDMCPLYK-----LQKTECGSHTKEETKTACLGD 220
+SGW T GN + ++ +MC + + T + ++ C GD
Sbjct: 208 ISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGD 267
Query: 221 PGSPMMCQLQQFDLWVLRGVLNF----GGETCPGLFLYTKVEDYSKWIT 265
G P+MC L ++ + + G+ ++ G PG+++ Y KW+T
Sbjct: 268 SGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSF--YQKWLT 314
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 82.4 bits (202), Expect = 6e-16
Identities = 66/232 (28%), Positives = 106/232 (45%), Gaps = 20/232 (8%)
Query: 52 EFPWVVSLQDSQYT--HLAFGCILSEFWVLSIASA---IQNRKDIVVIVGISNMDPSKIA 106
E+PW V+L + T HL G I+ W+L+ A +++ K + V GI N K
Sbjct: 398 EWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKED 457
Query: 107 HTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWV 166
+ + V IIIH+ + +IALLK +T +++ + + IC L + +CWV
Sbjct: 458 TSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPIC-LPSKGDRNVIYTDCWV 516
Query: 167 SGWNPTSATGNHMTMSVLRKIFVKDLDMCPL----YKLQKTECGSHTKEETKTACLGDPG 222
+GW KI + + C +K+ + +E K AC GD G
Sbjct: 517 TGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSG 576
Query: 223 SPMMCQLQQFDLWVLRGVLNFGGETC-----PGLFLYTKVEDYSKWITSKAE 269
P+ C + ++W L G+ ++ GE C PG +YT V +Y WI K +
Sbjct: 577 GPLSC--KHNEVWHLVGITSW-GEGCAQRERPG--VYTNVVEYVDWILEKTQ 623
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 82.4 bits (202), Expect = 6e-16
Identities = 79/282 (28%), Positives = 128/282 (45%), Gaps = 49/282 (17%)
Query: 17 LLVLLGLLYSSTSCG--VQKASVFYGPDPKEGLVSSMEFPWVVSLQDSQYTHLAFGCILS 74
LL+LLG+ + CG V + V G D G +PW VSL + + G ++S
Sbjct: 10 LLLLLGI----SVCGQPVYSSRVVGGQDAAAG-----RWPWQVSLH-FDHNFICGGSLVS 59
Query: 75 EFWVLSIASAIQ---NRKDIVVIVGISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSNNIA 131
E +L+ A IQ V +G + S+ +Y V+ I+IH + + + ++A
Sbjct: 60 ERLILTAAHCIQPTWTTFSYTVWLGSITVGDSR-KRVKYYVSKIVIHPKYQDTTA--DVA 116
Query: 132 LLKTDTAMHFGNLVQSICF--LGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKIFV 189
LLK + + F + + IC + + L PP CWV+GW + + S L++ V
Sbjct: 117 LLKLSSQVTFTSAILPICLPSVTKQLAIPPF---CWVTGWGKVKESSDRDYHSALQEAEV 173
Query: 190 KDLD-----------------MCPLYKLQKTECGSHTKEETKTACLGDPGSPMMCQLQQF 232
+D + P+ K K C T + K +C GD G P+ C +
Sbjct: 174 PIIDRQACEQLYNPIGIFLPALEPVIKEDKI-CAGDT-QNMKDSCKGDSGGPLSCHID-- 229
Query: 233 DLWVLRGVLNFG---GETCPGLFLYTKVEDYSKWITSKAERA 271
+W+ GV+++G G++ PG +YT V Y KWI + RA
Sbjct: 230 GVWIQTGVVSWGLECGKSLPG--VYTNVIYYQKWINATISRA 269
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 82.0 bits (201), Expect = 8e-16
Identities = 79/295 (26%), Positives = 129/295 (43%), Gaps = 36/295 (12%)
Query: 6 GLSGDGKMRGVLLVL-LGLLYSSTSCGVQKASVFYGPDPKEGLVSSM-----EFPWVVSL 59
G+ G G++ V ++L LGLL S T G + A G P+ + ++PW VS+
Sbjct: 5 GVLGPGQLGAVAILLYLGLLRSGT--GAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSI 62
Query: 60 QDSQYTHLAFGCILSEFWVLSIASAI---QNRKDIVVIVGISNMDPSKIAHTEYPVNTII 116
+ H+ G ++SE WVLS A +++ V +G +D + II
Sbjct: 63 T-YEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDII 121
Query: 117 IHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATG 176
H + +IALL+ + F ++ IC P L +C V+GW + +
Sbjct: 122 PHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGL-HCTVTGWGHVAPSV 180
Query: 177 NHMTMSVLRKIFVKDL--DMCP-LYKLQKTECGSHTKEET----------KTACLGDPGS 223
+ +T L+++ V + + C LY + H +E K AC GD G
Sbjct: 181 SLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGG 240
Query: 224 PMMCQLQQFDLWVLRGVLNFGGETC-----PGLFLYTKVEDYSKWITSKAERAGP 273
P+ C ++ LW L G++++ G+ C PG +YT Y+ WI SK P
Sbjct: 241 PLSCPVE--GLWYLTGIVSW-GDACGARNRPG--VYTLASSYASWIQSKVTELQP 290
>gi|34098976 marapsin 2 [Homo sapiens]
Length = 326
Score = 82.0 bits (201), Expect = 8e-16
Identities = 68/241 (28%), Positives = 113/241 (46%), Gaps = 30/241 (12%)
Query: 52 EFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQNRKDIVV---IVGISNMDPSKIA-- 106
++PW VS+ + H+ G IL+E+WVLS A K+I + VG+ N+ ++A
Sbjct: 70 KWPWQVSVHYAGL-HVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNL---RVAGN 125
Query: 107 HTE-YPVNTIIIHEDFD-NNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPV---L 161
HT+ Y VN +I+H ++ + + ++AL++ T + F V +C L TP V
Sbjct: 126 HTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVC-----LATPEVNLTS 180
Query: 162 QNCWVSGWNPTSATG------NHMTMSVLRKIFVKDLDMCPLYKLQKTECGSHTKEETKT 215
NCW +GW S G M + ++ + + L Y + C KT
Sbjct: 181 ANCWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMSYIMPDMLCAGDIL-NAKT 239
Query: 216 ACLGDPGSPMMCQLQQFDLWVLRGVLNFGGETCPGLF--LYTKVEDYSKWITSKAERAGP 273
C GD G P++C+ + W+ G++++G L+ +Y V +SKWI E
Sbjct: 240 VCEGDSGGPLVCEFNR--SWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIEITPT 297
Query: 274 P 274
P
Sbjct: 298 P 298
>gi|4503137 chymotrypsin-like [Homo sapiens]
Length = 264
Score = 82.0 bits (201), Expect = 8e-16
Identities = 70/259 (27%), Positives = 124/259 (47%), Gaps = 23/259 (8%)
Query: 18 LVLLGLLYSSTSCGVQ--KASVFYGPDPKEGLVSSM-EFPWVVSLQDSQYTHLAFGCILS 74
LVLLG SS CG+ K ++ + G + + +PW VSLQDS H G ++S
Sbjct: 10 LVLLG---SSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLIS 66
Query: 75 EFWVLSIASAIQNRKDIVVIVG----ISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSNNI 130
+ WV++ A + V++G SN +P ++ V+ I H +++ +M+N++
Sbjct: 67 QSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQV----LSVSRAITHPSWNSTTMNNDV 122
Query: 131 ALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKIFVK 190
LLK + + + +C L C +GW S GN +T + L+++ +
Sbjct: 123 TLLKLASPAQYTTRISPVCLASSNEALTEGL-TCVTTGWGRLSGVGN-VTPAHLQQVALP 180
Query: 191 --DLDMCPLY-KLQKTECGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGVLNFGGET 247
++ C Y T+ ++C GD G P++C Q+ + WVL G++++G +
Sbjct: 181 LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVC--QKGNTWVLIGIVSWGTKN 238
Query: 248 C--PGLFLYTKVEDYSKWI 264
C +YT+V +S WI
Sbjct: 239 CNVRAPAVYTRVSKFSTWI 257
>gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo
sapiens]
Length = 282
Score = 80.5 bits (197), Expect = 2e-15
Identities = 69/247 (27%), Positives = 112/247 (45%), Gaps = 41/247 (16%)
Query: 44 KEGLVSSMEFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQNRKDIV---VIVGISNM 100
K LV ++PW VS+ T++ G ++ WVL+ A +Q KD+ V+VG+
Sbjct: 45 KGKLVEVGKWPWQVSILFLG-TYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQR 103
Query: 101 DPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPV 160
+ T+ P+ ++IH+DF +N MS +IALLK ++ + VQ +C L + P +
Sbjct: 104 PENS---TQLPLTRMVIHKDF-SNLMSQDIALLKLRDSISWSPFVQPVC-LPNIKFKPSI 158
Query: 161 LQNCWVSGWNPTSATGNHMTMSVLRKIFVKDLDMCPLYKLQKTECGSHTKEETKTACLGD 220
CWV GW T G F+ D C +E + D
Sbjct: 159 GSMCWVIGWGTTGKKG-----------FLNHPD-------SVKSCCEFIRECFQFTLTVD 200
Query: 221 PGSPMMCQLQQFDLWVLRGVLNF----GGETCPGLFLYTKVEDYSKWITSKA------ER 270
GS ++CQ+ + W+ GV+++ G PG +YT +++WI ++ R
Sbjct: 201 SGSSLVCQMDK--TWIQIGVVSWSFSCGQRHFPG--IYTSTAHFNQWIRTEVANIRFISR 256
Query: 271 AGPPLSS 277
AGP S
Sbjct: 257 AGPAFLS 263
>gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo
sapiens]
Length = 282
Score = 80.5 bits (197), Expect = 2e-15
Identities = 69/247 (27%), Positives = 112/247 (45%), Gaps = 41/247 (16%)
Query: 44 KEGLVSSMEFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQNRKDIV---VIVGISNM 100
K LV ++PW VS+ T++ G ++ WVL+ A +Q KD+ V+VG+
Sbjct: 45 KGKLVEVGKWPWQVSILFLG-TYICSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVGVHQR 103
Query: 101 DPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPV 160
+ T+ P+ ++IH+DF +N MS +IALLK ++ + VQ +C L + P +
Sbjct: 104 PENS---TQLPLTRMVIHKDF-SNLMSQDIALLKLRDSISWSPFVQPVC-LPNIKFKPSI 158
Query: 161 LQNCWVSGWNPTSATGNHMTMSVLRKIFVKDLDMCPLYKLQKTECGSHTKEETKTACLGD 220
CWV GW T G F+ D C +E + D
Sbjct: 159 GSMCWVIGWGTTGKKG-----------FLNHPD-------SVKSCCEFIRECFQFTLTVD 200
Query: 221 PGSPMMCQLQQFDLWVLRGVLNF----GGETCPGLFLYTKVEDYSKWITSKA------ER 270
GS ++CQ+ + W+ GV+++ G PG +YT +++WI ++ R
Sbjct: 201 SGSSLVCQMDK--TWIQIGVVSWSFSCGQRHFPG--IYTSTAHFNQWIRTEVANIRFISR 256
Query: 271 AGPPLSS 277
AGP S
Sbjct: 257 AGPAFLS 263
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 79.7 bits (195), Expect = 4e-15
Identities = 64/238 (26%), Positives = 104/238 (43%), Gaps = 26/238 (10%)
Query: 53 FPWVVSLQDSQYT----HLAFGCILSEFWVLSIASAIQNRKDI--------VVIVGISNM 100
+PW+VSLQ Y H G +L+ WVL+ A + ++ + N
Sbjct: 54 WPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNN 113
Query: 101 DPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPV 160
P K E V IIIHE +++ + N+IAL++ + G + C P
Sbjct: 114 KPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRG 173
Query: 161 LQNCWVSGWNPTSATGNHMTMSVLR-KIFVKDLDMCPLY-----KLQKTE-CGSHTKEET 213
Q+CWV+GW + ++ ++ + DLD+C ++Q T C + +
Sbjct: 174 SQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKI 233
Query: 214 KTACLGDPGSPMMCQLQQFDLWVLRGVLNFGGETC----PGLFLYTKVEDYSKWITSK 267
T C GD G P+MC+ + +V+ G+ ++G PG +YT Y WI SK
Sbjct: 234 DT-CQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPG--IYTATWPYLNWIASK 288
>gi|15559207 elastase 2A preproprotein [Homo sapiens]
Length = 269
Score = 79.3 bits (194), Expect = 5e-15
Identities = 62/233 (26%), Positives = 106/233 (45%), Gaps = 27/233 (11%)
Query: 53 FPWVVSLQDS---QYTHLAFGCILSEFWVLSIASAIQNRKDIVVIVGISNMDPSKIAHTE 109
+PW VSLQ S ++ H G +++ WVL+ A I + + V +G N+ ++
Sbjct: 40 WPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLA 99
Query: 110 YPVNTIIIHEDFDNNSMS--NNIALLKTDTAMHFGNLVQSICFLGRMLHTPP---VLQN- 163
V+ I++H+D+++N +S N+IALLK + + +Q C PP +L N
Sbjct: 100 VSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLACL-------PPAGTILPNN 152
Query: 164 --CWVSGWNPTSATGNHMTMSVLRKIFVKDLDMCPLY----KLQKTECGSHTKEETKTAC 217
C+V+GW G + ++ V D C KT + ++C
Sbjct: 153 YPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWWGSSVKTSMICAGGDGVISSC 212
Query: 218 LGDPGSPMMCQLQQFDLWVLRGVLNFGGETCPGLF----LYTKVEDYSKWITS 266
GD G P+ CQ W + G+++FG + ++T+V +Y WI S
Sbjct: 213 NGDSGGPLNCQASD-GRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINS 264
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 79.3 bits (194), Expect = 5e-15
Identities = 75/269 (27%), Positives = 123/269 (45%), Gaps = 48/269 (17%)
Query: 26 SSTSCGVQKA--SVFYGPDPKEGLVSSMEFPWVVSLQDSQYTHLAFGCILSEFWVLSIAS 83
++T+CG + + G D +EG E+PW VS+Q + +H G +++E WVL+ A
Sbjct: 22 AATACGRPRMLNRMVGGQDTQEG-----EWPWQVSIQRNG-SHFCGGSLIAEQWVLTAAH 75
Query: 84 AIQNRKDIV---VIVGISNM-DPSKIAHTEYP-VNTIIIHEDFDNNSMSNNIALLKTDTA 138
+N + V++G + P H Y V + + + + S ++AL++ +
Sbjct: 76 CFRNTSETSLYQVLLGARQLVQPGP--HAMYARVRQVESNPLYQGTASSADVALVELEAP 133
Query: 139 MHFGNLVQSICFLGRMLHTPPVL----QNCWVSGWNPTSATGNHMTMSVLRKIFVKDLD- 193
+ F N + +C L P V+ NCWV+GW S +L+K+ V +D
Sbjct: 134 VPFTNYILPVC-----LPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDT 188
Query: 194 -MCPLYKLQKTECGSHTK------------EETKTACLGDPGSPMMCQLQQFDLWVLRGV 240
C L + TE G K E K AC GD G P++C + Q W+ GV
Sbjct: 189 PKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQ--SWLQAGV 246
Query: 241 LNFGGETC-----PGLFLYTKVEDYSKWI 264
+++ GE C PG +Y +V + WI
Sbjct: 247 ISW-GEGCARQNRPG--VYIRVTAHHNWI 272
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 77.8 bits (190), Expect = 2e-14
Identities = 63/234 (26%), Positives = 102/234 (43%), Gaps = 25/234 (10%)
Query: 52 EFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQNR---KDIVVIVG-ISNMDPSKIAH 107
++PW SLQ Y HL G +++ W+++ A + + K + VG +S +D +H
Sbjct: 227 QWPWQASLQFQGY-HLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSH 285
Query: 108 TEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVS 167
V I+ H + + N+IAL+K + F ++Q +C L P + CW S
Sbjct: 286 L---VEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVC-LPNSEENFPDGKVCWTS 341
Query: 168 GWNPT-------SATGNHMTMSVLRKIFVKDLDMCPLYKLQKTECGSHTKEETKTACLGD 220
GW T S NH + ++ D+ C + +C GD
Sbjct: 342 GWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGV-DSCQGD 400
Query: 221 PGSPMMCQLQQFDLWVLRGVLNFG----GETCPGLFLYTKVEDYSKWITSKAER 270
G P++CQ ++ LW L G +FG PG +YT+V + WI + ER
Sbjct: 401 SGGPLVCQERR--LWKLVGATSFGIGCAEVNKPG--VYTRVTSFLDWIHEQMER 450
>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
Length = 438
Score = 75.9 bits (185), Expect = 6e-14
Identities = 71/271 (26%), Positives = 121/271 (44%), Gaps = 27/271 (9%)
Query: 12 KMRGVLLVLLGLLYSSTSCGVQKASVFYGPDPKEGLVSSMEFPWVVSLQDSQYTHLAFGC 71
KMR +L G+ +S++ + +S E+PW SLQ H
Sbjct: 177 KMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGAS 236
Query: 72 ILSEFWVLSIASAIQNRKDIVVIVGI--SNMDPSKIAHTEYPVNTIIIHEDFDNNSMSNN 129
++S W+L+ A KD + + + P + V II+HE++ + N+
Sbjct: 237 LISNTWLLTAAHCFWKNKDPTQWIATFGATITPPAVKRN---VRKIILHENYHRETNEND 293
Query: 130 IALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKIFV 189
IAL++ T + F N+VQ +C + PP + +V+G+ S + + LR+ V
Sbjct: 294 IALVQLSTGVEFSNIVQRVCLPDSSIKLPP-KTSVFVTGFG--SIVDDGPIQNTLRQARV 350
Query: 190 KDL--DMC---PLYKLQKTE---CGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGVL 241
+ + D+C +Y T C E AC GD G P++ D+W + G++
Sbjct: 351 ETISTDVCNRKDVYDGLITPGMLCAGF-MEGKIDACKGDSGGPLV--YDNHDIWYIVGIV 407
Query: 242 NFGGETC-----PGLFLYTKVEDYSKWITSK 267
++ G++C PG +YT+V Y WI SK
Sbjct: 408 SW-GQSCALPKKPG--VYTRVTKYRDWIASK 435
>gi|58331211 elastase 2B preproprotein [Homo sapiens]
Length = 269
Score = 75.5 bits (184), Expect = 8e-14
Identities = 71/272 (26%), Positives = 115/272 (42%), Gaps = 35/272 (12%)
Query: 18 LVLLGLLYSSTSCGVQKASVFYGPDPKEGL----VSSMEFPWVVSLQDS---QYTHLAFG 70
L+L L+ + SCGV Y PD L +PW VSLQ S Q+ H G
Sbjct: 5 LLLSTLVAGALSCGVST----YAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG 60
Query: 71 CILSEFWVLSIASAIQNRKDIVVIVGISNMDPSKIAHTEYPVNTIIIHEDFDNNSMS--N 128
+++ WVL+ A I + V++G N+ ++ V+ I++H+D++++ +S N
Sbjct: 61 SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN 120
Query: 129 NIALLKTDTAMHFGNLVQSICFLGRMLHTPP---VLQN---CWVSGWNPTSATGNHMTMS 182
+IALLK + + +Q C PP +L N C+V+GW G
Sbjct: 121 DIALLKLANPVSLTDKIQLACL-------PPAGTILPNNYPCYVTGWGRLQTNGALPDDL 173
Query: 183 VLRKIFVKDLDMCPLY----KLQKTECGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLR 238
++ V D C KT + C GD G P+ CQ W +
Sbjct: 174 KQGRLLVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASD-GRWEVH 232
Query: 239 GVLNFGGETCPGLF----LYTKVEDYSKWITS 266
G+ + + ++T+V +Y+ WI S
Sbjct: 233 GIGSLTSVLGCNYYYKPSIFTRVSNYNDWINS 264
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 75.5 bits (184), Expect = 8e-14
Identities = 69/251 (27%), Positives = 118/251 (47%), Gaps = 28/251 (11%)
Query: 30 CGVQKASVFYGPDPK--EGLVSSM-EFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQ 86
CG+Q GP + G VSS E+PW SLQ + H+ G ++++ WV++ A Q
Sbjct: 568 CGLQ------GPSSRIVGGAVSSEGEWPWQASLQ-VRGRHICGGALIADRWVITAAHCFQ 620
Query: 87 NRKDI-----VVIVGISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHF 141
V +G + + V+ +++H + +S ++ALL+ D +
Sbjct: 621 EDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVR 680
Query: 142 GNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKIFVKDL--DMCP-LY 198
V+ +C R P L +CW++GW G + L+K+ V+ + D+C +Y
Sbjct: 681 SAAVRPVCLPARSHFFEPGL-HCWITGWGALREGGP--ISNALQKVDVQLIPQDLCSEVY 737
Query: 199 KLQKTE---CGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGVLNFG-GETCPGLF-L 253
+ Q T C + K + K AC GD G P++C+ W L G++++G G P F +
Sbjct: 738 RYQVTPRMLCAGYRKGK-KDACQGDSGGPLVCKALS-GRWFLAGLVSWGLGCGRPNYFGV 795
Query: 254 YTKVEDYSKWI 264
YT++ WI
Sbjct: 796 YTRITGVISWI 806
>gi|4503625 coagulation factor X preproprotein [Homo sapiens]
Length = 488
Score = 74.3 bits (181), Expect = 2e-13
Identities = 71/256 (27%), Positives = 110/256 (42%), Gaps = 18/256 (7%)
Query: 40 GPDPKEGLVSSMEFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQNRKDIVVIVGISN 99
G + K+G E PW L + + G ILSEF++L+ A + K V VG N
Sbjct: 238 GQECKDG-----ECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRN 292
Query: 100 MDPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGR--MLHT 157
+ + + V +I H F + +IA+L+ T + F V C R T
Sbjct: 293 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAEST 352
Query: 158 PPVLQNCWVSGWNPTSATGNHMTMSVLRKIFVKDLDMCPLYK----LQKTEC-GSHTKEE 212
+ VSG+ T G T + ++ D + C L Q C G TK+E
Sbjct: 353 LMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQE 412
Query: 213 TKTACLGDPGSPMMCQLQQFDLWVLRGVLNFG-GETCPGLF-LYTKVEDYSKWITSKAER 270
AC GD G P + + + D + + G++++G G G + +YTKV + KWI +
Sbjct: 413 --DACQGDSGGPHVTRFK--DTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 468
Query: 271 AGPPLSSLHHWEKLIS 286
G P + H E + S
Sbjct: 469 RGLPKAKSHAPEVITS 484
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 73.2 bits (178), Expect = 4e-13
Identities = 69/267 (25%), Positives = 121/267 (45%), Gaps = 41/267 (15%)
Query: 27 STSCGVQKASVFYG-PDPKEGLVSSMEFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAI 85
S +CG + + + G P P + ++PW VSLQ S H G ++ WVL+ A +
Sbjct: 153 SQACGHRVSRMIGGLPAPNK------KWPWQVSLQTSNIHHCG-GSLIDRRWVLTAAHCV 205
Query: 86 QN----RKDIVVIVGISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHF 141
++ GI D + H E II +FD +++++IAL ++++
Sbjct: 206 FRGCGWEGGRWLLAGIGRWDQAW-KHLE----DIIFPSNFDFATLTSDIALALLAYSVNY 260
Query: 142 GNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKI---FVKDLDMCPLY 198
+ +Q C ++ + CWV+GW S + + VL++ ++ C +
Sbjct: 261 SSHIQPACLPEKLFEVEAGTE-CWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEML 319
Query: 199 KLQK----------TECGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGVLNF----G 244
K + T CG + ++ K AC GD G P++C+L WV G++++ G
Sbjct: 320 KNKNISKSKMVTRGTVCGYN--DQGKDACQGDSGGPLVCELN--GTWVQVGIVSWGIGCG 375
Query: 245 GETCPGLFLYTKVEDYSKWITSKAERA 271
+ PG +YT+V Y KWI +A
Sbjct: 376 RKGYPG--VYTEVSFYKKWIIDHLRQA 400
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 73.2 bits (178), Expect = 4e-13
Identities = 69/267 (25%), Positives = 121/267 (45%), Gaps = 41/267 (15%)
Query: 27 STSCGVQKASVFYG-PDPKEGLVSSMEFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAI 85
S +CG + + + G P P + ++PW VSLQ S H G ++ WVL+ A +
Sbjct: 153 SQACGHRVSRMIGGLPAPNK------KWPWQVSLQTSNIHHCG-GSLIDRRWVLTAAHCV 205
Query: 86 QN----RKDIVVIVGISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHF 141
++ GI D + H E II +FD +++++IAL ++++
Sbjct: 206 FRGCGWEGGRWLLAGIGRWDQAW-KHLE----DIIFPSNFDFATLTSDIALALLAYSVNY 260
Query: 142 GNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKI---FVKDLDMCPLY 198
+ +Q C ++ + CWV+GW S + + VL++ ++ C +
Sbjct: 261 SSHIQPACLPEKLFEVEAGTE-CWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEML 319
Query: 199 KLQK----------TECGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGVLNF----G 244
K + T CG + ++ K AC GD G P++C+L WV G++++ G
Sbjct: 320 KNKNISKSKMVTRGTVCGYN--DQGKDACQGDSGGPLVCELN--GTWVQVGIVSWGIGCG 375
Query: 245 GETCPGLFLYTKVEDYSKWITSKAERA 271
+ PG +YT+V Y KWI +A
Sbjct: 376 RKGYPG--VYTEVSFYKKWIIDHLRQA 400
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 73.2 bits (178), Expect = 4e-13
Identities = 69/267 (25%), Positives = 121/267 (45%), Gaps = 41/267 (15%)
Query: 27 STSCGVQKASVFYG-PDPKEGLVSSMEFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAI 85
S +CG + + + G P P + ++PW VSLQ S H G ++ WVL+ A +
Sbjct: 153 SQACGHRVSRMIGGLPAPNK------KWPWQVSLQTSNIHHCG-GSLIDRRWVLTAAHCV 205
Query: 86 QN----RKDIVVIVGISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHF 141
++ GI D + H E II +FD +++++IAL ++++
Sbjct: 206 FRGCGWEGGRWLLAGIGRWDQAW-KHLE----DIIFPSNFDFATLTSDIALALLAYSVNY 260
Query: 142 GNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKI---FVKDLDMCPLY 198
+ +Q C ++ + CWV+GW S + + VL++ ++ C +
Sbjct: 261 SSHIQPACLPEKLFEVEAGTE-CWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEML 319
Query: 199 KLQK----------TECGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGVLNF----G 244
K + T CG + ++ K AC GD G P++C+L WV G++++ G
Sbjct: 320 KNKNISKSKMVTRGTVCGYN--DQGKDACQGDSGGPLVCELN--GTWVQVGIVSWGIGCG 375
Query: 245 GETCPGLFLYTKVEDYSKWITSKAERA 271
+ PG +YT+V Y KWI +A
Sbjct: 376 RKGYPG--VYTEVSFYKKWIIDHLRQA 400
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 73.2 bits (178), Expect = 4e-13
Identities = 66/263 (25%), Positives = 121/263 (46%), Gaps = 32/263 (12%)
Query: 21 LGLLYSSTSCGVQKAS-----VFYGPDPKEGLVSSMEFPWVVSLQDSQYTHLAFGCIL-S 74
+ LL + CG + A+ + G + G +PW SLQ H+ GC+L +
Sbjct: 781 ISLLCTKQDCGRRPAARMNKRILGGRTSRPG-----RWPWQCSLQSEPSGHIC-GCVLIA 834
Query: 75 EFWVLSIASAIQNRKDIV---VIVGISNMD-PSKIAHTEYPVNTIIIHEDFDNNSMSNNI 130
+ WVL++A + R++ V++GI+N+D PS T + V TII+H + + +I
Sbjct: 835 KKWVLTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQTRF-VKTIILHPRYSRAVVDYDI 893
Query: 131 ALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLR-KIFV 189
++++ + V+ +C P C+++GW GN M + ++ +
Sbjct: 894 SIVELSEDISETGYVRPVCLPNPEQWLEPDTY-CYITGW---GHMGNKMPFKLQEGEVRI 949
Query: 190 KDLDMCPLYKLQKT-----ECGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGVLNFG 244
L+ C Y KT C + + T +C+GD G P++C+ + W L G+ ++G
Sbjct: 950 ISLEHCQSYFDMKTITTRMICAGY-ESGTVDSCMGDSGGPLVCE-KPGGRWTLFGLTSWG 1007
Query: 245 G---ETCPGLFLYTKVEDYSKWI 264
G +Y+ V + +WI
Sbjct: 1008 SVCFSKVLGPGVYSNVSYFVEWI 1030
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 72.8 bits (177), Expect = 5e-13
Identities = 60/234 (25%), Positives = 106/234 (45%), Gaps = 29/234 (12%)
Query: 52 EFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQNRKD----IVVIVGISNMDPSKIAH 107
E+PW+VS+Q + TH G +L+ WV++ A ++ + V++G +
Sbjct: 60 EWPWIVSIQKNG-THHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRS 118
Query: 108 TEYPVNTIIIHEDFD-NNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWV 166
+ V + H + +IAL++ + ++ F V IC +H PP +CW+
Sbjct: 119 QKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNT-HCWI 177
Query: 167 SGWNPTS---ATGNHMTMSVLRKIFVKDLDMCPLYKLQKTECGSHTK--------EETKT 215
SGW + T+ L K+ + D ++C + G T+ E +
Sbjct: 178 SGWGSIQDGVPLPHPQTLQKL-KVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERD 236
Query: 216 ACLGDPGSPMMCQLQQFDLWVLRGVLNFGGETC-----PGLFLYTKVEDYSKWI 264
ACLGD G P+MCQ+ W+L G++++ GE C PG +Y + + W+
Sbjct: 237 ACLGDSGGPLMCQVD--GAWLLAGIISW-GEGCAERNRPG--VYISLSAHRSWV 285
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 70.9 bits (172), Expect = 2e-12
Identities = 67/271 (24%), Positives = 104/271 (38%), Gaps = 43/271 (15%)
Query: 17 LLVLLGLLYSSTSCGVQK--------ASVFYGPDPKEGLVSSMEFPWVVSLQDSQYTHLA 68
LL L+ ++ CGV + + G D G +PW VSLQD H
Sbjct: 6 LLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPG-----SWPWQVSLQDKTGFHFC 60
Query: 69 FGCILSEFWVLSIASAIQNRKDIVVIVGISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSN 128
G ++SE WV++ A D VV+ G + + + + + F +++N
Sbjct: 61 GGSLISEDWVVTAAHCGVRTSD-VVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNN 119
Query: 129 NIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKIF 188
+I LLK T F V ++C L P C +GW T N
Sbjct: 120 DITLLKLATPARFSQTVSAVC-LPSADDDFPAGTLCATTGWGKTKYNANKTP-------- 170
Query: 189 VKDLDMCPLYKLQKTECGSHTKEETK-----------TACLGDPGSPMMCQLQQFDLWVL 237
L L L EC ++C+GD G P++C Q+ W L
Sbjct: 171 -DKLQQAALPLLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVC--QKDGAWTL 227
Query: 238 RGVLNFGGETC----PGLFLYTKVEDYSKWI 264
G++++G +TC PG +Y +V W+
Sbjct: 228 VGIVSWGSDTCSTSSPG--VYARVTKLIPWV 256
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 70.9 bits (172), Expect = 2e-12
Identities = 58/233 (24%), Positives = 106/233 (45%), Gaps = 26/233 (11%)
Query: 53 FPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQ---NRKDIVVIVGISNMDPSKIAHTE 109
+PW V L+ + G I++ W+L+ A +Q N +I G + + +
Sbjct: 586 WPWQVGLRFLG-DYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQV 644
Query: 110 YPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVL---QNCWV 166
II+HEDF+ S ++IAL++ + + + ++V+ +C + H+ L + C V
Sbjct: 645 RRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVC----LPHSAEPLFSSEICAV 700
Query: 167 SGWNPTSATGNHMTMSVLRKIFVKDLDMC--------PLYKLQKTECGSHTKEETKTACL 218
+GW SA G + ++ V + ++C P +K C K C
Sbjct: 701 TGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQ 760
Query: 219 GDPGSPMMCQLQQFDLWVLRGVLNFGGETC----PGLFLYTKVEDYSKWITSK 267
GD G P++C+ + +VL G++++G PG+F +V + WI SK
Sbjct: 761 GDSGGPLVCR-HENGPFVLYGIVSWGAGCVQPWKPGVF--ARVMIFLDWIQSK 810
Score = 65.1 bits (157), Expect = 1e-10
Identities = 65/253 (25%), Positives = 109/253 (43%), Gaps = 31/253 (12%)
Query: 54 PWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQNR-----KDIVVIVGISNMDPSKIAHT 108
PW VSL+ ++ H G ++ E V++ A + + K+I V G ++
Sbjct: 59 PWQVSLKSDEH-HFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQ 117
Query: 109 EYPVNTIIIHEDFDNNS-MSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVS 167
PV+ II H ++++ MS +IALL + FGN VQ IC P + C S
Sbjct: 118 NIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGIL-CLSS 176
Query: 168 GWNPTSATGNHMTMSVLRKIFVKDLDMC-------PLYKLQKTECGSHTKEETKTACLGD 220
GW S T + + ++ + D C L L +T + + AC GD
Sbjct: 177 GWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGD 236
Query: 221 PGSPMMCQLQQFDLWVLRGVLNF----GGETCP--------GLFLYTKVEDYSKWITSKA 268
G P++C+ + +W+L G+ ++ G + P L +++KV + +IT
Sbjct: 237 SGGPLVCR-RGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQNL 295
Query: 269 ERA---GPPLSSL 278
G PLS +
Sbjct: 296 FTGLDRGQPLSKV 308
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 70.5 bits (171), Expect = 3e-12
Identities = 68/269 (25%), Positives = 122/269 (45%), Gaps = 36/269 (13%)
Query: 20 LLGLLYSSTSCGVQKAS------VFYGPDPKEGLVSSMEFPWVVSLQDSQYTHLAFGCIL 73
L+ L + SCG + A+ + G + KEG +PWVV L L ++
Sbjct: 762 LIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGA-----WPWVVGLYYGGRL-LCGASLV 815
Query: 74 SEFWVLSIASAIQNRK----DIVVIVGISNMDPSKIAHTEYP--VNTIIIHEDFDNNSMS 127
S W++S A + R I+G+ +M + + P ++ I+I+ ++
Sbjct: 816 SSDWLVSAAHCVYGRNLEPSKWTAILGL-HMKSNLTSPQTVPRLIDEIVINPHYNRRRKD 874
Query: 128 NNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKI 187
N+IA++ + +++ + +Q IC PP +NC ++GW G T ++L++
Sbjct: 875 NDIAMMHLEFKVNYTDYIQPICLPEENQVFPPG-RNCSIAGWGTVVYQGT--TANILQEA 931
Query: 188 FVKDLD------MCPLYKLQKTECGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGVL 241
V L P Y + + + +E +C GD G P+MC Q+ + W L GV
Sbjct: 932 DVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMC--QENNRWFLAGVT 989
Query: 242 NFGGETC----PGLFLYTKVEDYSKWITS 266
+FG + PG +Y +V +++WI S
Sbjct: 990 SFGYKCALPNRPG--VYARVSRFTEWIQS 1016
>gi|118498350 chymotrypsin B2 [Homo sapiens]
Length = 263
Score = 68.9 bits (167), Expect = 7e-12
Identities = 66/269 (24%), Positives = 101/269 (37%), Gaps = 39/269 (14%)
Query: 17 LLVLLGLLYSSTSCGVQK--------ASVFYGPDPKEGLVSSMEFPWVVSLQDSQYTHLA 68
LL LL ++ CGV + + G D G +PW VSLQD H
Sbjct: 6 LLSCWALLGTTFGCGVPAIHPVLSGLSRIVNGEDAVPG-----SWPWQVSLQDKTGFHFC 60
Query: 69 FGCILSEFWVLSIASAIQNRKDIVVIVGISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSN 128
G ++SE WV++ A D VV+ G + + + + + F +++N
Sbjct: 61 GGSLISEDWVVTAAHCGVRTSD-VVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNN 119
Query: 129 NIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKIF 188
+I LLK T F V ++C L P C +GW T N
Sbjct: 120 DITLLKLATPARFSQTVSAVC-LPSADDDFPAGTLCATTGWGKTKYNANKTP-------- 170
Query: 189 VKDLDMCPLYKLQKTECGSHTKEETK-----------TACLGDPGSPMMCQLQQFDLWVL 237
L L L EC ++C+GD G P++C Q+ W L
Sbjct: 171 -DKLQQAALPLLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVC--QKDGAWTL 227
Query: 238 RGVLNFGGETCPGL--FLYTKVEDYSKWI 264
G++++G TC +Y +V W+
Sbjct: 228 VGIVSWGSRTCSTTTPAVYARVAKLIPWV 256
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 68.9 bits (167), Expect = 7e-12
Identities = 66/260 (25%), Positives = 115/260 (44%), Gaps = 20/260 (7%)
Query: 30 CGVQKASVFYGPDPKEGLVSSMEFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQNRK 89
CG+Q A G S EFPW SL++++ H I++ W++S A +
Sbjct: 191 CGLQPAWRMAGRIVGGMEASPGEFPWQASLRENK-EHFCGAAIINARWLVSAAHCFNEFQ 249
Query: 90 DI---VVIVGISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQ 146
D V VG + + S+ + V I+ H ++ ++ ++A+L+ + + FG +Q
Sbjct: 250 DPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQ 309
Query: 147 SICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKIFVKDLDM---CPLYKLQKT 203
+C L H P + C +SGW + VL+K V+ LD LY T
Sbjct: 310 PVC-LPAATHIFPPSKKCLISGWGYLK-EDFLVKPEVLQKATVELLDQALCASLYGHSLT 367
Query: 204 E---CGSHTKEETKTACLGDPGSPMMCQLQQFDLWVLRGVLNFG----GETCPGLFLYTK 256
+ C + + +C GD G P++C+ + + L G++++G PG +Y +
Sbjct: 368 DRMVCAGYLDGKV-DSCQGDSGGPLVCE-EPSGRFFLAGIVSWGIGCAEARRPG--VYAR 423
Query: 257 VEDYSKWITSKAERAGPPLS 276
V WI +A PL+
Sbjct: 424 VTRLRDWILEATTKASMPLA 443
Score = 62.0 bits (149), Expect = 9e-10
Identities = 56/240 (23%), Positives = 107/240 (44%), Gaps = 19/240 (7%)
Query: 49 SSMEFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQNRK--DIVVIVGISNMDPSKIA 106
+S E PW VSL++ H ++ + W+LS A + K + +G +++ +
Sbjct: 511 ASGEVPWQVSLKEGS-RHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGS 569
Query: 107 HTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWV 166
+ + +++H ++ + ++A+L+ + + F +Q +C L + PV + C +
Sbjct: 570 PVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVC-LPLAIQKFPVGRKCMI 628
Query: 167 SGWNPTSATGNHMTMSVLRKIFVKDLDM---CPLYKLQKTE---CGSHTKEETKTACLGD 220
SGW T GN +L+K V +D LY T+ C E +C GD
Sbjct: 629 SGWGNTQ-EGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFL-EGKVDSCQGD 686
Query: 221 PGSPMMCQLQQFDLWVLRGVLNFGGETC----PGLFLYTKVEDYSKWITSKAERAGPPLS 276
G P+ C+ + ++ L G++++G PG +YT++ WI P+S
Sbjct: 687 SGGPLACE-EAPGVFYLAGIVSWGIGCAQVKKPG--VYTRITRLKGWILEIMSSQPLPMS 743
Score = 48.5 bits (114), Expect = 1e-05
Identities = 56/225 (24%), Positives = 92/225 (40%), Gaps = 20/225 (8%)
Query: 52 EFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQ---NRKDIVVIVGISNMDPSKIAHT 108
E+PW VSL + H +++E W+LS A + K +G + ++
Sbjct: 837 EWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAE-GQL 895
Query: 109 EYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSG 168
E V I H ++ ++ ++ALL+ + LV+ IC L PP C ++G
Sbjct: 896 E-RVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPIC-LPEPAPRPPDGTRCVITG 953
Query: 169 WNPTSATGNHMTMSVLRKIFVKDLDMCPLYKLQKTECGSHT-----KEETKTACLGDPGS 223
W G+ L+K V+ L + + S + +C GD G
Sbjct: 954 WGSVREGGSMARQ--LQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGVDSCSGDAGG 1011
Query: 224 PMMCQLQQFDLWVLRGVLNF----GGETCPGLFLYTKVEDYSKWI 264
P+ C+ + WVL GV ++ G PG +YT+V WI
Sbjct: 1012 PLACR-EPSGRWVLTGVTSWGYGCGRPHFPG--VYTRVAAVRGWI 1053
>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
sapiens]
Length = 414
Score = 68.6 bits (166), Expect = 1e-11
Identities = 57/237 (24%), Positives = 114/237 (48%), Gaps = 30/237 (12%)
Query: 54 PWVVSL----QDSQYTHLAFGCILSEFWVLSIASAI---QNRKDIVVIVGISNMDPSKIA 106
PW ++ + T++ G ++S WV+S ++D +V +G S ++ +
Sbjct: 174 PWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQG 233
Query: 107 HTEYPVNTIIIHEDFDNNSMS--NNIALLKTDT----AMHFGNLVQSICFLGRMLHTPPV 160
++ V +I+H+D+ ++++ N+IALLK + +Q+IC L M + P
Sbjct: 234 EMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTIC-LPSMYNDPQF 292
Query: 161 LQNCWVSGWNPTSATG----NHMTMSVLRKIFVKDLDMCPLYKLQKTE---CGSHTKEET 213
+C ++G+ ++T + M+V++ I ++ Y + T C + + +T
Sbjct: 293 GTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKT 352
Query: 214 KTACLGDPGSPMMCQLQQFDLWVLRGVLNFGG----ETCPGLFLYTKVEDYSKWITS 266
+ C GD G P++C LQ L G++++G + PG +YT+V + WI S
Sbjct: 353 DS-CQGDSGGPLVCSLQ--GRMTLTGIVSWGRGCALKDKPG--VYTRVSHFLPWIRS 404
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,023,464
Number of Sequences: 37866
Number of extensions: 706124
Number of successful extensions: 1658
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 1446
Number of HSP's gapped (non-prelim): 165
length of query: 395
length of database: 18,247,518
effective HSP length: 104
effective length of query: 291
effective length of database: 14,309,454
effective search space: 4164051114
effective search space used: 4164051114
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.