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Search of human proteins with 32528299
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo
sapiens]
(497 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo sa... 1040 0.0
gi|44680139 baculoviral IAP repeat-containing 8 [Homo sapiens] 410 e-114
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa... 285 9e-77
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap... 285 9e-77
gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo sap... 282 4e-76
gi|11545910 livin inhibitor of apoptosis isoform beta [Homo sapi... 148 1e-35
gi|119393878 NLR family, apoptosis inhibitory protein isoform 1 ... 140 3e-33
gi|21536421 livin inhibitor of apoptosis isoform alpha [Homo sap... 128 1e-29
gi|119393876 NLR family, apoptosis inhibitory protein isoform 2 ... 77 5e-14
gi|153792694 baculoviral IAP repeat-containing 6 [Homo sapiens] 72 2e-12
gi|38788243 myosin regulatory light chain interacting protein [H... 61 2e-09
gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens] 59 1e-08
gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens] 59 1e-08
gi|62865649 rififylin [Homo sapiens] 58 2e-08
gi|17432433 rififylin [Homo sapiens] 58 2e-08
gi|47716512 mex-3 homolog B [Homo sapiens] 52 1e-06
gi|30348954 mindbomb homolog 1 [Homo sapiens] 52 1e-06
gi|59859878 baculoviral IAP repeat-containing protein 5 isoform ... 51 2e-06
gi|53729363 leucine rich repeat and sterile alpha motif containi... 48 2e-05
gi|53729361 leucine rich repeat and sterile alpha motif containi... 48 2e-05
gi|53729359 leucine rich repeat and sterile alpha motif containi... 48 2e-05
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens] 45 2e-04
gi|21264330 mindbomb homolog 2 [Homo sapiens] 44 3e-04
gi|5729765 cell growth regulator with ring finger domain 1 [Homo... 43 8e-04
gi|14042925 ring finger protein 26 [Homo sapiens] 43 8e-04
gi|147902746 MEX3A protein [Homo sapiens] 42 0.002
gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1 ... 41 0.002
gi|59859882 baculoviral IAP repeat-containing protein 5 isoform ... 40 0.006
gi|59859880 baculoviral IAP repeat-containing protein 5 isoform ... 40 0.006
gi|58743365 ring finger protein 157 [Homo sapiens] 39 0.011
>gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo
sapiens]
Length = 497
Score = 1040 bits (2688), Expect = 0.0
Identities = 497/497 (100%), Positives = 497/497 (100%)
Query: 1 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT 60
MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT
Sbjct: 1 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT 60
Query: 61 VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY 120
VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY
Sbjct: 61 VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY 120
Query: 121 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT 180
LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT
Sbjct: 121 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT 180
Query: 181 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE 240
PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE
Sbjct: 181 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE 240
Query: 241 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC 300
SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC
Sbjct: 241 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC 300
Query: 301 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP 360
FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP
Sbjct: 301 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP 360
Query: 361 SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD 420
SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD
Sbjct: 361 SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD 420
Query: 421 SMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK 480
SMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK
Sbjct: 421 SMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK 480
Query: 481 CPMCYTVITFKQKIFMS 497
CPMCYTVITFKQKIFMS
Sbjct: 481 CPMCYTVITFKQKIFMS 497
>gi|44680139 baculoviral IAP repeat-containing 8 [Homo sapiens]
Length = 236
Score = 410 bits (1055), Expect = e-114
Identities = 189/236 (80%), Positives = 215/236 (91%)
Query: 262 MADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHA 321
M YEAR+ TFGTW+YSVNKEQLARAGFYA+G+ DKV+CFHCGGGL +WKP EDPWEQHA
Sbjct: 1 MTGYEARLITFGTWMYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHA 60
Query: 322 KWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIR 381
KWYPGCKYLLE+KG EYINNIHLT SLE LV+TT+KTPSLT+RI DTIF NPM+QEAIR
Sbjct: 61 KWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAIR 120
Query: 382 MGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQL 441
MGF FKD+KKIMEE+IQ SGSNYK+LEVLVADLV+AQKD+ ++E +QTSLQ+EIS EE L
Sbjct: 121 MGFDFKDVKKIMEERIQTSGSNYKTLEVLVADLVSAQKDTTENELNQTSLQREISPEEPL 180
Query: 442 RRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 497
RRLQEEKLCKICMDR+IA+VF+PCGHLVTCKQCAEAVD+CPMC VI FKQ++FMS
Sbjct: 181 RRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCSAVIDFKQRVFMS 236
Score = 63.9 bits (154), Expect = 3e-10
Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 160 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 219
M EARL +F W + +LA AG Y G D+VQCF CGG L NW+P + W +
Sbjct: 1 MTGYEARLITFGTW--MYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQ 58
Query: 220 HRRHFPNCFFVL 231
H + +P C ++L
Sbjct: 59 HAKWYPGCKYLL 70
Score = 42.7 bits (99), Expect = 8e-04
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 29 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 88
RL TF + V+ LARAGF G+ D V+CF C + W+ + +H K P
Sbjct: 7 RLITFGTWMYS--VNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYP 64
Query: 89 NCRFI 93
C+++
Sbjct: 65 GCKYL 69
>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 285 bits (728), Expect = 9e-77
Identities = 168/440 (38%), Positives = 233/440 (52%), Gaps = 59/440 (13%)
Query: 26 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 85
E R+ T++ FP+G PVS +LARAGF YTG D V+CF C +D W+ GDS +H+K
Sbjct: 29 ELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKK 88
Query: 86 VSPNCRFINGFYLEN------------SATQSTNS---GIQNGQYKVENYLGSRDHFALD 130
+ P+CRF+ N S T ST+S G +N Y +Y S +
Sbjct: 89 LYPSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNS 148
Query: 131 RPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLY 190
R ++ + L+R+ + AM +E ARL +FQ WP L+P +LA AG Y
Sbjct: 149 RANQDFSA-LMRSSY-----------HCAMNNENARLLTFQTWP-LTFLSPTDLAKAGFY 195
Query: 191 YTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNF 250
Y G GD+V CF CGGKL NWEP D A SEH RHFP C F+ E+ + R
Sbjct: 196 YIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFI---------ENQLQDTSRYT 246
Query: 251 PNSTNLPRNPSMADYEARIFTFGTWIYSV--NKEQLARAGFYALGEGDKVKCFHCGGGLT 308
+ N SM + AR TF W SV N EQLA AGFY +G D VKCF C GGL
Sbjct: 247 VS------NLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLR 300
Query: 309 DWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTH-SLEECLVRTTEK--------- 358
W+ +DPW QHAKW+P C+YL+ KGQE+I + ++ L E L+ T++
Sbjct: 301 CWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS 360
Query: 359 ----TPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADL 414
P D + P++ A+ MGFS +K+ ++ KI +G NY+ + LV DL
Sbjct: 361 IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDL 420
Query: 415 VNAQKDSMQDESSQTSLQKE 434
+NA+ + ++E + + +KE
Sbjct: 421 LNAEDEIREEERERATEEKE 440
Score = 87.8 bits (216), Expect = 2e-17
Identities = 35/64 (54%), Positives = 49/64 (76%)
Query: 434 EISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQK 493
++ EEQLRRLQEE+ CK+CMD+ ++IVF+PCGHLV CK CA ++ KCP+C + I +
Sbjct: 541 DLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVR 600
Query: 494 IFMS 497
F+S
Sbjct: 601 TFLS 604
Score = 65.9 bits (159), Expect = 8e-11
Identities = 41/113 (36%), Positives = 60/113 (53%), Gaps = 7/113 (6%)
Query: 235 LNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSV--NKEQLARAGFYAL 292
+NI S +S+ N+ L + S Y R+ T+ T+ V ++ LARAGFY
Sbjct: 1 MNIVENSIFLSNLMKSANTFELKYDLSCELY--RMSTYSTFPAGVPVSERSLARAGFYYT 58
Query: 293 GEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLT 345
G DKVKCF CG L +WK + P E+H K YP C+++ + +NN+ T
Sbjct: 59 GVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFV---QSLNSVNNLEAT 108
>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 285 bits (728), Expect = 9e-77
Identities = 168/440 (38%), Positives = 233/440 (52%), Gaps = 59/440 (13%)
Query: 26 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 85
E R+ T++ FP+G PVS +LARAGF YTG D V+CF C +D W+ GDS +H+K
Sbjct: 29 ELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKK 88
Query: 86 VSPNCRFINGFYLEN------------SATQSTNS---GIQNGQYKVENYLGSRDHFALD 130
+ P+CRF+ N S T ST+S G +N Y +Y S +
Sbjct: 89 LYPSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNS 148
Query: 131 RPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLY 190
R ++ + L+R+ + AM +E ARL +FQ WP L+P +LA AG Y
Sbjct: 149 RANQDFSA-LMRSSY-----------HCAMNNENARLLTFQTWP-LTFLSPTDLAKAGFY 195
Query: 191 YTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNF 250
Y G GD+V CF CGGKL NWEP D A SEH RHFP C F+ E+ + R
Sbjct: 196 YIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFI---------ENQLQDTSRYT 246
Query: 251 PNSTNLPRNPSMADYEARIFTFGTWIYSV--NKEQLARAGFYALGEGDKVKCFHCGGGLT 308
+ N SM + AR TF W SV N EQLA AGFY +G D VKCF C GGL
Sbjct: 247 VS------NLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLR 300
Query: 309 DWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTH-SLEECLVRTTEK--------- 358
W+ +DPW QHAKW+P C+YL+ KGQE+I + ++ L E L+ T++
Sbjct: 301 CWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS 360
Query: 359 ----TPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADL 414
P D + P++ A+ MGFS +K+ ++ KI +G NY+ + LV DL
Sbjct: 361 IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDL 420
Query: 415 VNAQKDSMQDESSQTSLQKE 434
+NA+ + ++E + + +KE
Sbjct: 421 LNAEDEIREEERERATEEKE 440
Score = 87.8 bits (216), Expect = 2e-17
Identities = 35/64 (54%), Positives = 49/64 (76%)
Query: 434 EISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQK 493
++ EEQLRRLQEE+ CK+CMD+ ++IVF+PCGHLV CK CA ++ KCP+C + I +
Sbjct: 541 DLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVR 600
Query: 494 IFMS 497
F+S
Sbjct: 601 TFLS 604
Score = 65.9 bits (159), Expect = 8e-11
Identities = 41/113 (36%), Positives = 60/113 (53%), Gaps = 7/113 (6%)
Query: 235 LNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSV--NKEQLARAGFYAL 292
+NI S +S+ N+ L + S Y R+ T+ T+ V ++ LARAGFY
Sbjct: 1 MNIVENSIFLSNLMKSANTFELKYDLSCELY--RMSTYSTFPAGVPVSERSLARAGFYYT 58
Query: 293 GEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLT 345
G DKVKCF CG L +WK + P E+H K YP C+++ + +NN+ T
Sbjct: 59 GVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFV---QSLNSVNNLEAT 108
>gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo
sapiens]
Length = 618
Score = 282 bits (722), Expect = 4e-76
Identities = 164/447 (36%), Positives = 243/447 (54%), Gaps = 41/447 (9%)
Query: 22 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 81
+F E R+ T++ FP+G PVS +LARAGF YTG D V+CF C +D W+ GDS +
Sbjct: 42 DFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQ 101
Query: 82 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETH-ADYL 140
+H+++ P+C FI + + S N+ + + + +H +L S + +
Sbjct: 102 KHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNSF-AHSLSPTLEHSSLFSGSYSSLSPNP 160
Query: 141 LRTGQVVDISDT-IYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 199
L + V DIS + P + AM +EEAR ++ WP L+P ELA AG YY G GD+V
Sbjct: 161 LNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWP-LTFLSPSELARAGFYYIGPGDRVA 219
Query: 200 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRN 259
CF CGGKL NWEP D A SEHRRHFPNC F+ +R N
Sbjct: 220 CFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSLETLRFSIS----------------N 263
Query: 260 PSMADYEARIFTFGTWIYSV--NKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPW 317
SM + AR+ TF W SV EQLA AGFY +G D VKCF C GGL W+ +DPW
Sbjct: 264 LSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPW 323
Query: 318 EQHAKWYPGCKYLLEQKGQEYINNI--HLTHSLEECLVRTTEKT-------------PSL 362
+HAKW+P C++L+ KGQE+++ I H LE+ L+ T++ T P
Sbjct: 324 VEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQ-LLSTSDTTGEENADPPIIHFGPGE 382
Query: 363 TRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSM 422
+ D + P+V+ A+ MGF+ +K+ ++ KI +G NYK++ +V+ L+NA+ +
Sbjct: 383 SSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVNDIVSALLNAEDEKR 442
Query: 423 QDESSQTSLQKEISTEEQLRRLQEEKL 449
++E + Q E + L +++ ++
Sbjct: 443 EEEKEK---QAEEMASDDLSLIRKNRM 466
Score = 87.4 bits (215), Expect = 3e-17
Identities = 34/63 (53%), Positives = 50/63 (79%)
Query: 435 ISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKI 494
+S EEQLRRLQEE+ CK+CMD+ +++VF+PCGHLV C++CA ++ KCP+C +I +
Sbjct: 556 LSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRT 615
Query: 495 FMS 497
F+S
Sbjct: 616 FLS 618
Score = 62.0 bits (149), Expect = 1e-09
Identities = 48/153 (31%), Positives = 71/153 (46%), Gaps = 11/153 (7%)
Query: 236 NIRS--ESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSV--NKEQLARAGFYA 291
NI+S E + SD N + + S Y R+ T+ T+ V ++ LARAGFY
Sbjct: 17 NIKSIMEDSTILSDWTNSNKQKMKYDFSCELY--RMSTYSTFPAGVPVSERSLARAGFYY 74
Query: 292 LGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLE----QKGQEYINNIHLTHS 347
G DKVKCF CG L +WK + P ++H + YP C ++ G N + +S
Sbjct: 75 TGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNS 134
Query: 348 LEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAI 380
L T E + SL ++ NP+ A+
Sbjct: 135 FAHSLSPTLEHS-SLFSGSYSSLSPNPLNSRAV 166
>gi|11545910 livin inhibitor of apoptosis isoform beta [Homo
sapiens]
Length = 280
Score = 148 bits (374), Expect = 1e-35
Identities = 81/243 (33%), Positives = 123/243 (50%), Gaps = 43/243 (17%)
Query: 257 PRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSE 314
P P M E R+ +F W + V E LA AGF+ G DKV+CF C GGL WK +
Sbjct: 79 PAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGD 138
Query: 315 DPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNP 374
DPW +HAKW+P C++LL KG+++++++ THS
Sbjct: 139 DPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHS--------------------------- 171
Query: 375 MVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKE 434
+ + +++ + + S Y L + +Q ES+Q ++
Sbjct: 172 ---QLLGSWDPWEEPEDAAPVAPSVPASGYPELP--------TPRREVQSESAQEPGARD 220
Query: 435 ISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKI 494
+ E QLRRLQEE+ CK+C+DR ++IVFVPCGHLV C +CA + CP+C + + +
Sbjct: 221 V--EAQLRRLQEERTCKVCLDRAVSIVFVPCGHLV-CAECAPGLQLCPICRAPVRSRVRT 277
Query: 495 FMS 497
F+S
Sbjct: 278 FLS 280
Score = 81.3 bits (199), Expect = 2e-15
Identities = 37/77 (48%), Positives = 51/77 (66%)
Query: 155 PRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCD 214
P P M SEE RL SF +WP A + P LA+AG ++TG D+V+CF C G L++W+ D
Sbjct: 79 PAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGD 138
Query: 215 RAWSEHRRHFPNCFFVL 231
W+EH + FP+C F+L
Sbjct: 139 DPWTEHAKWFPSCQFLL 155
Score = 58.5 bits (140), Expect = 1e-08
Identities = 26/65 (40%), Positives = 37/65 (56%)
Query: 29 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 88
RL +F ++P + V LA AGF +TG D VRCF C+ + W+ GD H K P
Sbjct: 90 RLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFP 149
Query: 89 NCRFI 93
+C+F+
Sbjct: 150 SCQFL 154
>gi|119393878 NLR family, apoptosis inhibitory protein isoform 1
[Homo sapiens]
Length = 1403
Score = 140 bits (353), Expect = 3e-33
Identities = 120/407 (29%), Positives = 179/407 (43%), Gaps = 66/407 (16%)
Query: 26 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 85
E RLKTF + S +A AGF +TG ++CF C + + H++
Sbjct: 60 EAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKR 119
Query: 86 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 145
P+C GF L I +V+N L SR LR G+
Sbjct: 120 FHPDC----GFLLNKDV-----GNIAKYDIRVKN-LKSR----------------LRGGK 153
Query: 146 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAH-LTPRELASAGLYYTGIGDQVQCFCCG 204
+ EEARL SF+NWP Y ++P L+ AG +TG D VQCF CG
Sbjct: 154 M------------RYQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCG 201
Query: 205 GKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLN------IRSESDAVS-SDRNFPNS---T 254
G L NWE D W EH + FP C F+ + + I+S V + +F NS
Sbjct: 202 GCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYIQSYKGFVDITGEHFVNSWVQR 261
Query: 255 NLPR-----NPSMADYEA-RIFTFGTWIY--SVNKEQLARAGFYALGEGDKVKCFHCGGG 306
LP N S+ YE R+ +F W +V LA+AG + G D V+CF CGG
Sbjct: 262 ELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGC 321
Query: 307 LTDWKPSEDPWEQHAKWYPGCKYLLEQKGQ-EYINNIHLTHSLEECLVRTTEKTPSLTRR 365
L W+ +DP + H + +P C +L K E ++ L E L T+E
Sbjct: 322 LEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSRGELCELLETTSES------N 375
Query: 366 IDDTIFQNPMVQEAIRMGFS-FKDIKKIMEE-KIQISGSNYKSLEVL 410
++D+I P+V E + F++ K + E+ + + ++++ + +L
Sbjct: 376 LEDSIAVGPIVPEMAQGEAQWFQEAKNLNEQLRAAYTSASFRHMSLL 422
Score = 124 bits (311), Expect = 2e-28
Identities = 65/188 (34%), Positives = 101/188 (53%), Gaps = 10/188 (5%)
Query: 157 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRA 216
N M SE RLK+F + Y+ P+E+A+AG Y+TG+ +QCFCC L
Sbjct: 54 NSQMRSEAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLP 113
Query: 217 WSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMA--DYEARIFTFGT 274
+H+R P+C F+L +++ + D N + R M + EAR+ +F
Sbjct: 114 IEDHKRFHPDCGFLLNKDVG-----NIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRN 168
Query: 275 W---IYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLL 331
W + ++ L+ AGF G+ D V+CF CGG L +W+ +DPW++HAKW+P C++L
Sbjct: 169 WPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLR 228
Query: 332 EQKGQEYI 339
+K E I
Sbjct: 229 SKKSSEEI 236
Score = 118 bits (295), Expect = 1e-26
Identities = 89/268 (33%), Positives = 125/268 (46%), Gaps = 46/268 (17%)
Query: 23 FVEEFNRLKTFANFPSG-SPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 81
+ EE RL +F N+P +S L+ AGF++TG+ DTV+CFSC + W+ GD
Sbjct: 156 YQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWK 215
Query: 82 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRD----HFA---LDRPSE 134
H K P C F+ +S S + QY +++Y G D HF + R
Sbjct: 216 EHAKWFPKCEFL----------RSKKSSEEITQY-IQSYKGFVDITGEHFVNSWVQRELP 264
Query: 135 THADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGI 194
+ Y +D+I+ EE RL SF++WP + + LA AGL+YTGI
Sbjct: 265 MASAYC---------NDSIFAY------EELRLDSFKDWPRESAVGVAALAKAGLFYTGI 309
Query: 195 GDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVS--------- 245
D VQCF CGG L+ W+ D +H R FPNC F+ + D S
Sbjct: 310 KDIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSRGELCELLE 369
Query: 246 --SDRNFPNSTNL-PRNPSMADYEARIF 270
S+ N +S + P P MA EA+ F
Sbjct: 370 TTSESNLEDSIAVGPIVPEMAQGEAQWF 397
>gi|21536421 livin inhibitor of apoptosis isoform alpha [Homo
sapiens]
Length = 298
Score = 128 bits (322), Expect = 1e-29
Identities = 78/245 (31%), Positives = 120/245 (48%), Gaps = 29/245 (11%)
Query: 257 PRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSE 314
P P M E R+ +F W + V E LA AGF+ G DKV+CF C GGL WK +
Sbjct: 79 PAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGD 138
Query: 315 DPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNP 374
DPW +HAKW+P C++LL KG+++++++ THS L+ + + ++ P
Sbjct: 139 DPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHSQ---LLGSWDPW-------EEPEDAAP 188
Query: 375 MVQEAIRMGFSFKDI--KKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQ 432
+ G+ +++ E Q G E A V + E+ LQ
Sbjct: 189 VAPSVPASGYPELPTPRREVQSESAQEPG-GVSPAEAQRAWWVLEPPGARDVEAQLRRLQ 247
Query: 433 KEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQ 492
+E + CK+C+DR ++IVFVPCGHLV C +CA + CP+C + +
Sbjct: 248 EE-------------RTCKVCLDRAVSIVFVPCGHLV-CAECAPGLQLCPICRAPVRSRV 293
Query: 493 KIFMS 497
+ F+S
Sbjct: 294 RTFLS 298
Score = 81.3 bits (199), Expect = 2e-15
Identities = 37/77 (48%), Positives = 51/77 (66%)
Query: 155 PRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCD 214
P P M SEE RL SF +WP A + P LA+AG ++TG D+V+CF C G L++W+ D
Sbjct: 79 PAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGD 138
Query: 215 RAWSEHRRHFPNCFFVL 231
W+EH + FP+C F+L
Sbjct: 139 DPWTEHAKWFPSCQFLL 155
Score = 58.5 bits (140), Expect = 1e-08
Identities = 26/65 (40%), Positives = 37/65 (56%)
Query: 29 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 88
RL +F ++P + V LA AGF +TG D VRCF C+ + W+ GD H K P
Sbjct: 90 RLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFP 149
Query: 89 NCRFI 93
+C+F+
Sbjct: 150 SCQFL 154
>gi|119393876 NLR family, apoptosis inhibitory protein isoform 2
[Homo sapiens]
Length = 1241
Score = 76.6 bits (187), Expect = 5e-14
Identities = 47/120 (39%), Positives = 61/120 (50%), Gaps = 12/120 (10%)
Query: 163 EEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRR 222
EE RL SF++WP + + LA AGL+YTGI D VQCF CGG L+ W+ D +H R
Sbjct: 116 EELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDDHTR 175
Query: 223 HFPNCFFVLGRNLNIRSESDAVS-----------SDRNFPNSTNL-PRNPSMADYEARIF 270
FPNC F+ + D S S+ N +S + P P MA EA+ F
Sbjct: 176 CFPNCPFLQNMKSSAEVTPDLQSRGELCELLETTSESNLEDSIAVGPIVPEMAQGEAQWF 235
Score = 67.4 bits (163), Expect = 3e-11
Identities = 32/86 (37%), Positives = 44/86 (51%)
Query: 23 FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGR 82
F E RL +F ++P S V + LA+AG YTG D V+CFSC +++WQ GD +
Sbjct: 113 FAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDD 172
Query: 83 HRKVSPNCRFINGFYLENSATQSTNS 108
H + PNC F+ T S
Sbjct: 173 HTRCFPNCPFLQNMKSSAEVTPDLQS 198
Score = 61.6 bits (148), Expect = 2e-09
Identities = 44/168 (26%), Positives = 79/168 (47%), Gaps = 11/168 (6%)
Query: 248 RNFPNSTNLPRNPSMADYEARIFTFGTWIY--SVNKEQLARAGFYALGEGDKVKCFHCGG 305
R P ++ + A E R+ +F W +V LA+AG + G D V+CF CGG
Sbjct: 99 RELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGG 158
Query: 306 GLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQ-EYINNIHLTHSLEECLVRTTEKTPSLTR 364
L W+ +DP + H + +P C +L K E ++ L E L T+E
Sbjct: 159 CLEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSRGELCELLETTSES------ 212
Query: 365 RIDDTIFQNPMVQEAIRMGFS-FKDIKKIMEE-KIQISGSNYKSLEVL 410
++D+I P+V E + F++ K + E+ + + ++++ + +L
Sbjct: 213 NLEDSIAVGPIVPEMAQGEAQWFQEAKNLNEQLRAAYTSASFRHMSLL 260
>gi|153792694 baculoviral IAP repeat-containing 6 [Homo sapiens]
Length = 4857
Score = 71.6 bits (174), Expect = 2e-12
Identities = 45/123 (36%), Positives = 56/123 (45%), Gaps = 20/123 (16%)
Query: 160 MYSEEARLKSFQNWPD--YAHLTPRELASAGLYYTGIG---DQVQCFCCGGKLKNWEPCD 214
MYSE R ++F +WP Y P +A AG Y+ D+ CF C L WEP D
Sbjct: 283 MYSEANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTD 342
Query: 215 RAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSM---ADYEARIFT 271
WSEH RH PNC FV G + +N P S L +P+ D RI
Sbjct: 343 EPWSEHERHSPNCPFVKGEH------------TQNVPLSVTLATSPAQFPCTDGTDRISC 390
Query: 272 FGT 274
FG+
Sbjct: 391 FGS 393
Score = 48.9 bits (115), Expect = 1e-05
Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 11/85 (12%)
Query: 271 TFGTWIYS----VNKEQLARAGFY---ALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKW 323
TF +W + + +A+AGFY A D+ CF C L W+P+++PW +H +
Sbjct: 292 TFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPWSEHERH 351
Query: 324 YPGCKYLLEQKGQEYINNIHLTHSL 348
P C ++ KG E+ N+ L+ +L
Sbjct: 352 SPNCPFV---KG-EHTQNVPLSVTL 372
Score = 44.7 bits (104), Expect = 2e-04
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 5/80 (6%)
Query: 26 EFNRLKTFANFPSGSP--VSASTLARAGFLY---TGEGDTVRCFSCHAAVDRWQYGDSAV 80
E NR +TF ++P +A+AGF + + D CF+C + W+ D
Sbjct: 286 EANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPW 345
Query: 81 GRHRKVSPNCRFINGFYLEN 100
H + SPNC F+ G + +N
Sbjct: 346 SEHERHSPNCPFVKGEHTQN 365
>gi|38788243 myosin regulatory light chain interacting protein [Homo
sapiens]
Length = 445
Score = 61.2 bits (147), Expect = 2e-09
Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
Query: 415 VNAQKDSMQDESSQ-TSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQ 473
+ + + SM S + S Q+ +E+LR+L+E LC +C + I F PCGH V C+
Sbjct: 351 LKSSESSMNCSSCEGLSCQQTRVLQEKLRKLKEAMLCMVCCEEEINSTFCPCGHTVCCES 410
Query: 474 CAEAVDKCPMCYTVITFKQKIFM 496
CA + CP+C + + Q +++
Sbjct: 411 CAAQLQSCPVCRSRVEHVQHVYL 433
>gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens]
Length = 373
Score = 58.5 bits (140), Expect = 1e-08
Identities = 24/66 (36%), Positives = 38/66 (57%)
Query: 432 QKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFK 491
QK QL+ +++ LC+ICMD I V + CGH+VTC +C + + +CP+C +
Sbjct: 308 QKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRA 367
Query: 492 QKIFMS 497
+F S
Sbjct: 368 VHVFKS 373
>gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens]
Length = 372
Score = 58.5 bits (140), Expect = 1e-08
Identities = 24/66 (36%), Positives = 38/66 (57%)
Query: 432 QKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFK 491
QK QL+ +++ LC+ICMD I V + CGH+VTC +C + + +CP+C +
Sbjct: 307 QKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRA 366
Query: 492 QKIFMS 497
+F S
Sbjct: 367 VHVFKS 372
>gi|62865649 rififylin [Homo sapiens]
Length = 363
Score = 57.8 bits (138), Expect = 2e-08
Identities = 23/52 (44%), Positives = 33/52 (63%)
Query: 446 EEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 497
EE LCKICMD I V + CGH+VTC +C + +++CP+C + +F S
Sbjct: 312 EENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVFRS 363
>gi|17432433 rififylin [Homo sapiens]
Length = 363
Score = 57.8 bits (138), Expect = 2e-08
Identities = 23/52 (44%), Positives = 33/52 (63%)
Query: 446 EEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 497
EE LCKICMD I V + CGH+VTC +C + +++CP+C + +F S
Sbjct: 312 EENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVFRS 363
>gi|47716512 mex-3 homolog B [Homo sapiens]
Length = 569
Score = 52.4 bits (124), Expect = 1e-06
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 410 LVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLV 469
L A L Q SS +S S+ R + + C +C + + VPCGH +
Sbjct: 478 LGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNL 537
Query: 470 TCKQCAEAV-----DKCPMCYTVITFKQKIF 495
C +CA + +CP+C+T +T +IF
Sbjct: 538 FCMECANRICEKSEPECPVCHTAVTQAIRIF 568
>gi|30348954 mindbomb homolog 1 [Homo sapiens]
Length = 1006
Score = 52.0 bits (123), Expect = 1e-06
Identities = 19/58 (32%), Positives = 35/58 (60%)
Query: 431 LQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVI 488
++K + +EQ++ + + C +C D+ A++F PCGH+ C+ CA + KC C V+
Sbjct: 847 VKKCLICKEQVQSRTKIEECVVCSDKKAAVLFQPCGHMCACENCANLMKKCVQCRAVV 904
Score = 50.8 bits (120), Expect = 3e-06
Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 3/85 (3%)
Query: 405 KSLEVLVADLVNAQKDSMQDESSQTSLQKEIST-EEQLRRLQEEKLCKICMDRNIAIVFV 463
KS E D+ + +Q + T++ ++ ++QL+ ++E+ +C +C+DR ++F+
Sbjct: 917 KSSEDATDDISSGNIPVLQKDKDNTNVNADVQKLQQQLQDIKEQTMCPVCLDRLKNMIFL 976
Query: 464 PCGHLVTCKQCAEAVDKCPMCYTVI 488
CGH TC+ C + + +CP+C I
Sbjct: 977 -CGH-GTCQLCGDRMSECPICRKAI 999
Score = 44.3 bits (103), Expect = 3e-04
Identities = 17/45 (37%), Positives = 24/45 (53%)
Query: 450 CKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKI 494
C +C D +F PCGH+ TC C+ V KC +C + + KI
Sbjct: 819 CMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSRTKI 863
>gi|59859878 baculoviral IAP repeat-containing protein 5 isoform 1
[Homo sapiens]
Length = 142
Score = 51.2 bits (121), Expect = 2e-06
Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 161 YSEEARLKSFQNWP--DYAHLTPRELASAGLYYTGIG---DQVQCFCCGGKLKNWEPCDR 215
+ ++ R+ +F+NWP + TP +A AG + D QCF C +L+ WEP D
Sbjct: 13 FLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDD 72
Query: 216 AWSEHRRHFPNCFFV 230
EH++H C F+
Sbjct: 73 PIEEHKKHSSGCAFL 87
Score = 49.3 bits (116), Expect = 8e-06
Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 9/82 (10%)
Query: 260 PSMADYEARIFTFGTWIY----SVNKEQLARAGFYAL---GEGDKVKCFHCGGGLTDWKP 312
P + D+ RI TF W + + E++A AGF E D +CF C L W+P
Sbjct: 12 PFLKDH--RISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEP 69
Query: 313 SEDPWEQHAKWYPGCKYLLEQK 334
+DP E+H K GC +L +K
Sbjct: 70 DDDPIEEHKKHSSGCAFLSVKK 91
Score = 46.2 bits (108), Expect = 7e-05
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
Query: 28 NRLKTFANFP--SGSPVSASTLARAGFLYT---GEGDTVRCFSCHAAVDRWQYGDSAVGR 82
+R+ TF N+P G + +A AGF++ E D +CF C ++ W+ D +
Sbjct: 17 HRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEE 76
Query: 83 HRKVSPNCRFIN 94
H+K S C F++
Sbjct: 77 HKKHSSGCAFLS 88
>gi|53729363 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 48.1 bits (113), Expect = 2e-05
Identities = 16/48 (33%), Positives = 30/48 (62%)
Query: 450 CKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 497
C +C++R ++F+ CGH+ C+QC + + CP+C I + +I+ S
Sbjct: 675 CVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIYHS 722
>gi|53729361 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 48.1 bits (113), Expect = 2e-05
Identities = 16/48 (33%), Positives = 30/48 (62%)
Query: 450 CKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 497
C +C++R ++F+ CGH+ C+QC + + CP+C I + +I+ S
Sbjct: 675 CVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIYHS 722
>gi|53729359 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 48.1 bits (113), Expect = 2e-05
Identities = 16/48 (33%), Positives = 30/48 (62%)
Query: 450 CKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 497
C +C++R ++F+ CGH+ C+QC + + CP+C I + +I+ S
Sbjct: 675 CVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIYHS 722
>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
Length = 659
Score = 44.7 bits (104), Expect = 2e-04
Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 13/95 (13%)
Query: 400 SGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIA 459
S N+ L + + N TS S+ + RR + C IC + +
Sbjct: 566 STGNHVGLPIYIPAFSNGTNSYSSSNGGSTS-----SSPPESRRKHD---CVICFENEVI 617
Query: 460 IVFVPCGHLVTCKQCAEAV-----DKCPMCYTVIT 489
VPCGH + C +CA + CP+C T +T
Sbjct: 618 AALVPCGHNLFCMECANKICEKRTPSCPVCQTAVT 652
>gi|21264330 mindbomb homolog 2 [Homo sapiens]
Length = 1013
Score = 44.3 bits (103), Expect = 3e-04
Identities = 21/59 (35%), Positives = 34/59 (57%), Gaps = 2/59 (3%)
Query: 438 EEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFM 496
+ + R+++E C IC+D +I +VF CGH C C A+ CP+C I + +IF+
Sbjct: 957 QSRYRQMEERITCPICIDSHIRLVF-QCGH-GACAPCGSALSACPICRQPIRDRIQIFV 1013
Score = 42.0 bits (97), Expect = 0.001
Identities = 14/42 (33%), Positives = 24/42 (57%)
Query: 450 CKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFK 491
C +C + + ++F PC H C++CA + KC C V++ K
Sbjct: 890 CLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSKK 931
>gi|5729765 cell growth regulator with ring finger domain 1 [Homo
sapiens]
Length = 332
Score = 42.7 bits (99), Expect = 8e-04
Identities = 23/100 (23%), Positives = 46/100 (46%), Gaps = 6/100 (6%)
Query: 391 KIMEEKIQISGSNYKSLEVLVADLVN----AQKDSMQDESSQTSLQKEISTEEQLRRLQE 446
+I+ + + ++ + L+ L N + S +++++ SL +++ E E
Sbjct: 209 RILYQYLLLAQGQFHDLKQLFMSANNNFTPSNNSSSEEKNTDRSLLEKVGLSESEVEPSE 268
Query: 447 E--KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMC 484
E K C +C + + V +PC H C C + +CPMC
Sbjct: 269 ENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMC 308
>gi|14042925 ring finger protein 26 [Homo sapiens]
Length = 433
Score = 42.7 bits (99), Expect = 8e-04
Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 7/51 (13%)
Query: 441 LRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK-------CPMC 484
L+ +E K C IC D++ ++ +PC HL C+ C E + + CP+C
Sbjct: 371 LKEQEERKKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLC 421
>gi|147902746 MEX3A protein [Homo sapiens]
Length = 520
Score = 41.6 bits (96), Expect = 0.002
Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 5/51 (9%)
Query: 450 CKICMDRNIAIVFVPCGHLVTCKQCAEAV-----DKCPMCYTVITFKQKIF 495
C +C + + VPCGH + C +CA + +CP+C+ T +IF
Sbjct: 469 CMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIF 519
>gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1
[Homo sapiens]
Length = 352
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 422 MQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAV--- 478
MQ+E + Q +S + R + C +C+ + VF+ CGH+ +C +C A+
Sbjct: 275 MQEEFQEHEAQL-LSRAKPEDRESLKSACVVCLSSFKSCVFLECGHVCSCTECYRALPEP 333
Query: 479 DKCPMCYTVIT 489
KCP+C IT
Sbjct: 334 KKCPICRQAIT 344
>gi|59859882 baculoviral IAP repeat-containing protein 5 isoform 3
[Homo sapiens]
Length = 165
Score = 39.7 bits (91), Expect = 0.006
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 161 YSEEARLKSFQNWP--DYAHLTPRELASAGLYYTGIG---DQVQCFCCGGKLKNWEPCD 214
+ ++ R+ +F+NWP + TP +A AG + D QCF C +L+ WEP D
Sbjct: 13 FLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDD 71
Score = 37.0 bits (84), Expect = 0.041
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 28 NRLKTFANFP--SGSPVSASTLARAGFLYT---GEGDTVRCFSCHAAVDRWQYGDSAVG 81
+R+ TF N+P G + +A AGF++ E D +CF C ++ W+ D +G
Sbjct: 17 HRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIG 75
Score = 36.6 bits (83), Expect = 0.054
Identities = 28/95 (29%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Query: 260 PSMADYEARIFTFGTWIY----SVNKEQLARAGFYAL---GEGDKVKCFHCGGGLTDWKP 312
P + D+ RI TF W + + E++A AGF E D +CF C L W+P
Sbjct: 12 PFLKDH--RISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEP 69
Query: 313 SEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHS 347
+DP Y L +G H HS
Sbjct: 70 DDDPIGPGTVAYACNTSTLGGRGGRITREEHKKHS 104
>gi|59859880 baculoviral IAP repeat-containing protein 5 isoform 2
[Homo sapiens]
Length = 137
Score = 39.7 bits (91), Expect = 0.006
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 161 YSEEARLKSFQNWP--DYAHLTPRELASAGLYYTGIG---DQVQCFCCGGKLKNWEPCD 214
+ ++ R+ +F+NWP + TP +A AG + D QCF C +L+ WEP D
Sbjct: 13 FLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDD 71
Score = 37.0 bits (84), Expect = 0.041
Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 9/67 (13%)
Query: 260 PSMADYEARIFTFGTWIY----SVNKEQLARAGFYAL---GEGDKVKCFHCGGGLTDWKP 312
P + D+ RI TF W + + E++A AGF E D +CF C L W+P
Sbjct: 12 PFLKDH--RISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEP 69
Query: 313 SEDPWEQ 319
+DP ++
Sbjct: 70 DDDPMQR 76
Score = 35.0 bits (79), Expect = 0.16
Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
Query: 28 NRLKTFANFP--SGSPVSASTLARAGFLYT---GEGDTVRCFSCHAAVDRWQYGDSAVGR 82
+R+ TF N+P G + +A AGF++ E D +CF C ++ W+ D + R
Sbjct: 17 HRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPMQR 76
>gi|58743365 ring finger protein 157 [Homo sapiens]
Length = 679
Score = 38.9 bits (89), Expect = 0.011
Identities = 38/181 (20%), Positives = 71/181 (39%), Gaps = 50/181 (27%)
Query: 308 TDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRID 367
++W E ++ + YP + + +G EY + H+ L+ T EK D
Sbjct: 181 SEWAEEELGFDLDREVYPLVVHAVVDEGDEYFGHCHV-------LLGTFEK------HTD 227
Query: 368 DTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESS 427
T P+ Q+ + G S+ +++E I + Y + + VA+ D + D S+
Sbjct: 228 GTFCVKPLKQKQVVDGVSY-----LLQEIYGIE-NKYNTQDSKVAE------DEVSDNSA 275
Query: 428 QTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAV----DKCPM 483
+ C +C+ + +PC HL C CA+ + + CP+
Sbjct: 276 E---------------------CVVCLSDVRDTLILPCRHLCLCNTCADTLRYQANNCPI 314
Query: 484 C 484
C
Sbjct: 315 C 315
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,896,357
Number of Sequences: 37866
Number of extensions: 923796
Number of successful extensions: 2863
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 2711
Number of HSP's gapped (non-prelim): 172
length of query: 497
length of database: 18,247,518
effective HSP length: 106
effective length of query: 391
effective length of database: 14,233,722
effective search space: 5565385302
effective search space used: 5565385302
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.