Guide to the Human Genome
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Search of human proteins with 32483412

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32483412 connexin 40 [Homo sapiens]
         (358 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32483412 connexin 40 [Homo sapiens]                                743   0.0  
gi|6631083 connexin 40 [Homo sapiens]                                 743   0.0  
gi|55953076 connexin 50 [Homo sapiens]                                312   3e-85
gi|22779877 connexin 46 [Homo sapiens]                                307   1e-83
gi|62865885 connexin 37 [Homo sapiens]                                276   3e-74
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]       276   3e-74
gi|14211941 gap junction protein, alpha 10 [Homo sapiens]             267   9e-72
gi|4504001 connexin 43 [Homo sapiens]                                 267   1e-71
gi|122939172 connexin 45 [Homo sapiens]                               224   7e-59
gi|69122473 connexin 45 [Homo sapiens]                                224   7e-59
gi|42558283 gap junction protein beta 2 [Homo sapiens]                202   5e-52
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]       201   6e-52
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]       201   8e-52
gi|159032020 gap junction protein, beta 6 [Homo sapiens]              198   7e-51
gi|158966714 gap junction protein, beta 6 [Homo sapiens]              198   7e-51
gi|158966717 gap junction protein, beta 6 [Homo sapiens]              198   7e-51
gi|40254837 gap junction protein, beta 6 [Homo sapiens]               198   7e-51
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]       190   1e-48
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]         190   1e-48
gi|23397464 gap junction protein, beta 4 [Homo sapiens]               184   8e-47
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]    182   3e-46
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]      174   1e-43
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]        164   1e-40
gi|54607056 connexin 31 [Homo sapiens]                                161   7e-40
gi|13128960 connexin 31 [Homo sapiens]                                161   7e-40
gi|145699105 connexin40.1 [Homo sapiens]                              144   2e-34
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]     135   4e-32
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]           87   2e-17
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]           87   2e-17
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]           87   2e-17

>gi|32483412 connexin 40 [Homo sapiens]
          Length = 358

 Score =  743 bits (1918), Expect = 0.0
 Identities = 358/358 (100%), Positives = 358/358 (100%)

Query: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
           MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
Sbjct: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60

Query: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
           CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
Sbjct: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120

Query: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
           GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
Sbjct: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180

Query: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240
           TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
Sbjct: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240

Query: 241 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ 300
           PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
Sbjct: 241 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ 300

Query: 301 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV 358
           VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
Sbjct: 301 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV 358


>gi|6631083 connexin 40 [Homo sapiens]
          Length = 358

 Score =  743 bits (1918), Expect = 0.0
 Identities = 358/358 (100%), Positives = 358/358 (100%)

Query: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
           MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
Sbjct: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60

Query: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
           CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
Sbjct: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120

Query: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
           GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
Sbjct: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180

Query: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240
           TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
Sbjct: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240

Query: 241 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ 300
           PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
Sbjct: 241 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ 300

Query: 301 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV 358
           VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
Sbjct: 301 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV 358


>gi|55953076 connexin 50 [Homo sapiens]
          Length = 433

 Score =  312 bits (800), Expect = 3e-85
 Identities = 188/435 (43%), Positives = 243/435 (55%), Gaps = 79/435 (18%)

Query: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
           MGDWSFLGN LEEV++HSTV+G+VWLTVLFIFR+L+LGTAAE  WGDEQ+DF C+T QPG
Sbjct: 1   MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60

Query: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
           C+NVCYD+AFPISHIR WVLQIIFVSTPSL+Y+GHA+H VRM+EKRK REAE   +  G+
Sbjct: 61  CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120

Query: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
                P     + S   +G  +  L+GTLL TY+C I+ +T  EVGFIVG YF+YG  + 
Sbjct: 121 NG--GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL 178

Query: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240
            L+ C R PCP+ V+C+VSRPTEK +FI+FML+VA++SL L++ EL HLG K IR    +
Sbjct: 179 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR 238

Query: 241 P-------------------------------RQHMAKCQLSGPSVGIVQ-SCTPPPDFN 268
           P                                + +         VG+V+ S  P   FN
Sbjct: 239 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN 298

Query: 269 QC---LENGPGGKFFNPFSNNMAS----------------QQNTDNLVTEQVRGQEQ--T 307
           Q    +  GP G     +   + S                ++  +  V E+    E+  T
Sbjct: 299 QFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTT 358

Query: 308 PGEGFIQVRYGQKPEVPNGVSPGHR---------------------LPHGYHSDKR---R 343
             +  + V  G+K E P     G +                      P     D R   R
Sbjct: 359 EEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSR 418

Query: 344 LSKASSKARSDDLSV 358
           LSKASS+ARSDDL+V
Sbjct: 419 LSKASSRARSDDLTV 433


>gi|22779877 connexin 46 [Homo sapiens]
          Length = 435

 Score =  307 bits (786), Expect = 1e-83
 Identities = 142/236 (60%), Positives = 177/236 (75%), Gaps = 4/236 (1%)

Query: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
           MGDWSFLG  LE   +HSTV+GKVWLTVLFIFR+LVLG AAE  WGDEQ+DF C+T QPG
Sbjct: 1   MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG 60

Query: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
           C+NVCYD+AFPISHIR+W LQIIFVSTP+L+Y+GH +H VRM+EK+K RE E   +    
Sbjct: 61  CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP 120

Query: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
              E P    +      +  GR+ + G LL TYV +I+ +T  EVGFI GQYF+YG  L 
Sbjct: 121 SPKEPPQDNPSS----RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK 176

Query: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
            L+ C R PCP+ V+C++SRPTEK +FI+FMLAVA  SLLL++ E+YHLGWKK++Q
Sbjct: 177 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQ 232


>gi|62865885 connexin 37 [Homo sapiens]
          Length = 333

 Score =  276 bits (705), Expect = 3e-74
 Identities = 147/325 (45%), Positives = 206/325 (63%), Gaps = 10/325 (3%)

Query: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
           MGDW FL   L++V +HSTVVGK+WLTVLFIFR+L+LG A ES WGDEQ+DF C+T QPG
Sbjct: 1   MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60

Query: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE----RAKE 116
           C NVCYDQAFPISHIRYWVLQ +FVSTP+LVY+GH ++  R +E+ + +E E     AK+
Sbjct: 61  CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120

Query: 117 VRGSGSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
            +   +      + A++S  E+  GR+ ++G L+ TYV S+L ++ +E GF+ GQ+ +YG
Sbjct: 121 PQVERALAAVERQMAKISVAED--GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYG 178

Query: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
             +  + VC+R+PCP+ V+C+VSRPTEK +FI+FML V  +SL+L+L EL HL  + +  
Sbjct: 179 WTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL-S 237

Query: 237 RFVKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNL 296
           R ++ RQ        G S       T    F   +  GP       ++   +S+QN  NL
Sbjct: 238 RGMRARQGQDAPPTQGTS---SDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANL 294

Query: 297 VTEQVRGQEQTPGEGFIQVRYGQKP 321
            TE+     + P       + GQKP
Sbjct: 295 TTEERLASSRPPLFLDPPPQNGQKP 319


>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
          Length = 515

 Score =  276 bits (705), Expect = 3e-74
 Identities = 143/314 (45%), Positives = 200/314 (63%), Gaps = 21/314 (6%)

Query: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
           MGDW+ LG+ LEEVH HST++GK+WLT+LFIFRMLVLG AAE  W DEQ+ F C+T QPG
Sbjct: 1   MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60

Query: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
           C+NVCYDQAFPIS IRYWVLQ+IFVS+PSLVYMGHA++ +R+ E+ + R   + +     
Sbjct: 61  CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120

Query: 121 GSYEYPVAEK---AELSCWEEGN-GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
             +E P   +    EL   E+    +  L+GTLL TYV  I  R+ +EVGF++GQY +YG
Sbjct: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180

Query: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
             L  L  C   PCP+ ++C+VSRPTEK +F++FM ++A +SL L++ E++HLG+KKI++
Sbjct: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240

Query: 237 ---------------RFVKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFN 281
                             K +Q++AK Q    S   ++     PD+N  +E       + 
Sbjct: 241 GLWGKYKLKKEHNEFHANKAKQNVAKYQ--STSANSLKRLPSAPDYNLLVEKQTHTAVYP 298

Query: 282 PFSNNMASQQNTDN 295
             +++   Q N DN
Sbjct: 299 SLNSSSVFQPNPDN 312


>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
          Length = 543

 Score =  267 bits (683), Expect = 9e-72
 Identities = 132/244 (54%), Positives = 173/244 (70%), Gaps = 4/244 (1%)

Query: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
           MGDW+ LG  LEEVH HST+VGK+WLT+LFIFRMLVL  AAE  W DEQ+ F C+T QPG
Sbjct: 1   MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60

Query: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE--RAKEVR 118
           C N+CYD AFPIS IR+WVLQIIFVS+PSLVYMGHA++ +R  EK + R+    RA+   
Sbjct: 61  CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120

Query: 119 GSGSYEYPVAEKAELSCWEEGN--GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
                E       EL   EE     ++ L+G LL TYV  IL R+ +EVGF++GQY +YG
Sbjct: 121 PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYG 180

Query: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
             +  L+ C + PCP+ V+C+VSRPTEK +F++FM ++AA+SLLL++ E++HLG +KI +
Sbjct: 181 FQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240

Query: 237 RFVK 240
              K
Sbjct: 241 TLYK 244


>gi|4504001 connexin 43 [Homo sapiens]
          Length = 382

 Score =  267 bits (682), Expect = 1e-71
 Identities = 160/396 (40%), Positives = 233/396 (58%), Gaps = 52/396 (13%)

Query: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
           MGDWS LG  L++V  +ST  GKVWL+VLFIFR+L+LGTA ES+WGDEQ+ FRC+T QPG
Sbjct: 1   MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG 60

Query: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
           C+NVCYD++FPISH+R+WVLQIIFVS P+L+Y+ H  + +R +EK   +E E  K  +  
Sbjct: 61  CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKE-EELKVAQTD 119

Query: 121 GSYEYPVAEKAELSCWEEG---NGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGI 177
           G       ++ E+  ++ G   +G++ ++G LL TY+ SIL ++  EV F++ Q++IYG 
Sbjct: 120 GVNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGF 179

Query: 178 FLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQR 237
            L+ ++ C+R PCPH V+C++SRPTEK +FI+FML V+ +SL L++ EL+++ +K ++ R
Sbjct: 180 SLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDR 239

Query: 238 FVKPRQHMAKCQLSGPSVGIVQSCTPPPD--------FNQCLE--------NGPGGKFFN 281
            VK +        S P      + +P  D        FN C          + PG K   
Sbjct: 240 -VKGK--------SDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVT 290

Query: 282 PFSNN--------MASQQNTDNLVTEQVR-GQEQTPGEGFIQVRYGQKPEVPNG------ 326
              NN         AS+QN  N   EQ R GQ  +     I   + Q  + P+       
Sbjct: 291 GDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGST----ISNSHAQPFDFPDDNQNSKK 346

Query: 327 VSPGHRLPHGYHSDKRRLSKASSKA----RSDDLSV 358
           ++ GH L      D+R  S+ASS+A    R DDL +
Sbjct: 347 LAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI 382


>gi|122939172 connexin 45 [Homo sapiens]
          Length = 396

 Score =  224 bits (572), Expect = 7e-59
 Identities = 135/385 (35%), Positives = 200/385 (51%), Gaps = 42/385 (10%)

Query: 4   WSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQN 63
           WSFL   LEE+H HST VGK+WLTVL +FR+++     ES + DEQ+ F C+T QPGC+N
Sbjct: 3   WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62

Query: 64  VCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEK-----------------R 106
           VCYD   P+SH+R+WV QII V+TPS++Y+G+A+H +   E                  +
Sbjct: 63  VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122

Query: 107 KLREAERAKEVRGSGSYEYPV---------AEKAELSCWEEGNGRIALQGTLLNTYVCSI 157
           + R  E  +E        YP           E+++     +G  RI   G L+  YV  +
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYVLQL 181

Query: 158 LIRTTMEVGFIVGQYFIYGIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAAL 217
           L RT  EVGF++GQYF+YG  +   +VC R PCPH ++C++SRPTEK +F++ M  V  L
Sbjct: 182 LARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGL 241

Query: 218 SLLLSLAELYHLGWKKIRQRFVKPRQHMAKCQLSGPSV----GIVQSCTPPPDFNQCLEN 273
            LLL++ E+ HLG+  IR      R+     +L  P          + + PP +N  ++ 
Sbjct: 242 CLLLNIWEMLHLGFGTIRDSLNSKRR-----ELEDPGAYNYPFTWNTPSAPPGYNIAVK- 295

Query: 274 GPGGKFFNPFSN-NMASQQNTDNLVTEQVRG--QEQTPGE-GFIQVRYGQKPEVPNGVSP 329
            P    +   SN  +A +QN  N   EQ  G  +E  P +   +Q       E  +    
Sbjct: 296 -PDQIQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQ 354

Query: 330 GHRLPHGYHSDKRRLSKASSKARSD 354
            +   +  H  + + +K  SKA S+
Sbjct: 355 AYSHQNNPHGPREKKAKVGSKAGSN 379


>gi|69122473 connexin 45 [Homo sapiens]
          Length = 396

 Score =  224 bits (572), Expect = 7e-59
 Identities = 135/385 (35%), Positives = 200/385 (51%), Gaps = 42/385 (10%)

Query: 4   WSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQN 63
           WSFL   LEE+H HST VGK+WLTVL +FR+++     ES + DEQ+ F C+T QPGC+N
Sbjct: 3   WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62

Query: 64  VCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEK-----------------R 106
           VCYD   P+SH+R+WV QII V+TPS++Y+G+A+H +   E                  +
Sbjct: 63  VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122

Query: 107 KLREAERAKEVRGSGSYEYPV---------AEKAELSCWEEGNGRIALQGTLLNTYVCSI 157
           + R  E  +E        YP           E+++     +G  RI   G L+  YV  +
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYVLQL 181

Query: 158 LIRTTMEVGFIVGQYFIYGIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAAL 217
           L RT  EVGF++GQYF+YG  +   +VC R PCPH ++C++SRPTEK +F++ M  V  L
Sbjct: 182 LARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGL 241

Query: 218 SLLLSLAELYHLGWKKIRQRFVKPRQHMAKCQLSGPSV----GIVQSCTPPPDFNQCLEN 273
            LLL++ E+ HLG+  IR      R+     +L  P          + + PP +N  ++ 
Sbjct: 242 CLLLNIWEMLHLGFGTIRDSLNSKRR-----ELEDPGAYNYPFTWNTPSAPPGYNIAVK- 295

Query: 274 GPGGKFFNPFSN-NMASQQNTDNLVTEQVRG--QEQTPGE-GFIQVRYGQKPEVPNGVSP 329
            P    +   SN  +A +QN  N   EQ  G  +E  P +   +Q       E  +    
Sbjct: 296 -PDQIQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQ 354

Query: 330 GHRLPHGYHSDKRRLSKASSKARSD 354
            +   +  H  + + +K  SKA S+
Sbjct: 355 AYSHQNNPHGPREKKAKVGSKAGSN 379


>gi|42558283 gap junction protein beta 2 [Homo sapiens]
          Length = 226

 Score =  202 bits (513), Expect = 5e-52
 Identities = 105/228 (46%), Positives = 144/228 (63%), Gaps = 17/228 (7%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           DW  L   L  V+KHST +GK+WLTVLFIFR+++L  AA+  WGDEQADF C+T+QPGC+
Sbjct: 2   DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCK 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           NVCYD  FPISHIR W LQ+IFVSTP+L+   H  +  R  EK++       K ++G   
Sbjct: 62  NVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAY--RRHEKKR-------KFIKGEIK 112

Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
            E+   E+ +         ++ ++G+L  TY  SI  R   E  F+   Y +Y G  +  
Sbjct: 113 SEFKDIEEIKTQ-------KVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQR 165

Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
           L  C   PCP+ V+C+VSRPTEK VF VFM+AV+ + +LL++ EL +L
Sbjct: 166 LVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYL 213


>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
          Length = 321

 Score =  201 bits (512), Expect = 6e-52
 Identities = 107/281 (38%), Positives = 156/281 (55%), Gaps = 46/281 (16%)

Query: 1   MGDWSFLGNFLEE-VHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQP 59
           MG+W+ L   LE  V +HST++G++ LTV+ IFR+L++    E+ + DEQ  F C+T+QP
Sbjct: 1   MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60

Query: 60  GCQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKL----------- 108
           GC   CYD+AFPISHIRYWV QII V TPSL ++ +++H    Q +R+            
Sbjct: 61  GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120

Query: 109 -------------------REAERAKE--VRGSGSYEYPVAEKAELSCWE---------- 137
                              RE ++ +   V G        +++ E  C E          
Sbjct: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180

Query: 138 ---EGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVCRRSPCPHPV 194
                  ++  Q  +   Y+  ++ R  +E+GF+VGQYF+YG  +  L+ C R PC   V
Sbjct: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240

Query: 195 NCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR 235
            CYVSRPTEK VF+VFM AV+ + ++L+LAEL HLGW+KI+
Sbjct: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIK 281


>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
          Length = 439

 Score =  201 bits (511), Expect = 8e-52
 Identities = 114/286 (39%), Positives = 155/286 (54%), Gaps = 60/286 (20%)

Query: 4   WSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQN 63
           WSFL   LEE+H HST VGKVWLTVL +FR+++     E+ + DEQA F C+T QPGC N
Sbjct: 6   WSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDN 65

Query: 64  VCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRM---QEKRKL-------REAER 113
           VCYD   P+SH+R+WV QI+ +STPS++Y+G+A+H +     QE+R+        R A R
Sbjct: 66  VCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRAPR 125

Query: 114 A---------------------------KEVRGSGSYEYPVAEKAELSCWEEG------- 139
           A                           +E   +G+ E    E+AE +  EE        
Sbjct: 126 AHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAE-GAGEEAEEAGAEEACTKAVGA 184

Query: 140 --------------NGRIALQGT-LLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHV 184
                         +GR  +Q   L+  YV  ++ R   EV F+VGQY +YG  +     
Sbjct: 185 DGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVRPFFP 244

Query: 185 CRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLG 230
           C R PCPH V+C+VSRPTEK VF++ M  V+ L LLL+L E+ HLG
Sbjct: 245 CSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLG 290


>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  198 bits (503), Expect = 7e-51
 Identities = 98/228 (42%), Positives = 141/228 (61%), Gaps = 17/228 (7%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           DW  L  F+  V+KHST +GKVW+TV+FIFR+++L  AA+  WGDEQ DF C+T+QPGC+
Sbjct: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           NVCYD  FP+SHIR W LQ+IFVSTP+L+   H  +  R +  RK R  E+  + +    
Sbjct: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY-YRHETTRKFRRGEKRNDFKDIED 120

Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
            +                 ++ ++G+L  TY  SI  R   E  F+   YF+Y G  L  
Sbjct: 121 IK---------------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPW 165

Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
           +  C   PCP+ V+C++SRPTEK VF +FM++ + + +LL++AEL +L
Sbjct: 166 VLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213


>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  198 bits (503), Expect = 7e-51
 Identities = 98/228 (42%), Positives = 141/228 (61%), Gaps = 17/228 (7%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           DW  L  F+  V+KHST +GKVW+TV+FIFR+++L  AA+  WGDEQ DF C+T+QPGC+
Sbjct: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           NVCYD  FP+SHIR W LQ+IFVSTP+L+   H  +  R +  RK R  E+  + +    
Sbjct: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY-YRHETTRKFRRGEKRNDFKDIED 120

Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
            +                 ++ ++G+L  TY  SI  R   E  F+   YF+Y G  L  
Sbjct: 121 IK---------------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPW 165

Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
           +  C   PCP+ V+C++SRPTEK VF +FM++ + + +LL++AEL +L
Sbjct: 166 VLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213


>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  198 bits (503), Expect = 7e-51
 Identities = 98/228 (42%), Positives = 141/228 (61%), Gaps = 17/228 (7%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           DW  L  F+  V+KHST +GKVW+TV+FIFR+++L  AA+  WGDEQ DF C+T+QPGC+
Sbjct: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           NVCYD  FP+SHIR W LQ+IFVSTP+L+   H  +  R +  RK R  E+  + +    
Sbjct: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY-YRHETTRKFRRGEKRNDFKDIED 120

Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
            +                 ++ ++G+L  TY  SI  R   E  F+   YF+Y G  L  
Sbjct: 121 IK---------------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPW 165

Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
           +  C   PCP+ V+C++SRPTEK VF +FM++ + + +LL++AEL +L
Sbjct: 166 VLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213


>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  198 bits (503), Expect = 7e-51
 Identities = 98/228 (42%), Positives = 141/228 (61%), Gaps = 17/228 (7%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           DW  L  F+  V+KHST +GKVW+TV+FIFR+++L  AA+  WGDEQ DF C+T+QPGC+
Sbjct: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           NVCYD  FP+SHIR W LQ+IFVSTP+L+   H  +  R +  RK R  E+  + +    
Sbjct: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY-YRHETTRKFRRGEKRNDFKDIED 120

Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
            +                 ++ ++G+L  TY  SI  R   E  F+   YF+Y G  L  
Sbjct: 121 IK---------------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPW 165

Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
           +  C   PCP+ V+C++SRPTEK VF +FM++ + + +LL++AEL +L
Sbjct: 166 VLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213


>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  190 bits (483), Expect = 1e-48
 Identities = 101/228 (44%), Positives = 142/228 (62%), Gaps = 18/228 (7%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           +W+ L   L  V++HST +G+VWL+V+FIFR++VL  AAES WGDE++ F C+T+QPGC 
Sbjct: 2   NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           +VCYDQ FPISH+R W LQ+I VSTP+L+   H  H   + EK+ LR       + G G 
Sbjct: 62  SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHI-EKKMLR-------LEGHGD 113

Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
                     L   E    ++ + GTL  TYV S++ R   E  F+   Y +Y G  +  
Sbjct: 114 ---------PLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVR 164

Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
           L  C   PCP+ V+C+VSRPTEK VF VFMLA + + ++L++AE+ +L
Sbjct: 165 LVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212


>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  190 bits (483), Expect = 1e-48
 Identities = 101/228 (44%), Positives = 142/228 (62%), Gaps = 18/228 (7%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           +W+ L   L  V++HST +G+VWL+V+FIFR++VL  AAES WGDE++ F C+T+QPGC 
Sbjct: 2   NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           +VCYDQ FPISH+R W LQ+I VSTP+L+   H  H   + EK+ LR       + G G 
Sbjct: 62  SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHI-EKKMLR-------LEGHGD 113

Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
                     L   E    ++ + GTL  TYV S++ R   E  F+   Y +Y G  +  
Sbjct: 114 ---------PLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVR 164

Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
           L  C   PCP+ V+C+VSRPTEK VF VFMLA + + ++L++AE+ +L
Sbjct: 165 LVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212


>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
          Length = 266

 Score =  184 bits (468), Expect = 8e-47
 Identities = 94/248 (37%), Positives = 145/248 (58%), Gaps = 23/248 (9%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           +W+FL   L  V+K+STV+ ++WL+V+FIFR+LV   AAE  W DEQ DF C+T QPGC 
Sbjct: 2   NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           NVCYD+ FP+SH+R W LQ+I V+ PSL+ + H  +    + K  L+    A  +  + S
Sbjct: 62  NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLS 121

Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIF-LTT 181
            +                     +G L  TY+ S++ +  ++ GF+   + +Y  + +  
Sbjct: 122 KK---------------------RGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPR 160

Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVKP 241
           +  C   PCPH V+CY+SRPTEK VF  FM+  AA+ +LL+L+E+++L  K+  + F  P
Sbjct: 161 VVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIF-GP 219

Query: 242 RQHMAKCQ 249
           R    +C+
Sbjct: 220 RHRRPRCR 227


>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
          Length = 294

 Score =  182 bits (463), Expect = 3e-46
 Identities = 93/233 (39%), Positives = 135/233 (57%), Gaps = 19/233 (8%)

Query: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
           MG+W+FLG+ L+ V   S +VG++WL V+ IFR+LVL T   + + DEQ +F C+T+QPG
Sbjct: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60

Query: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
           C+  CYD+AFP+SH R+W+  I+ +S P ++++ ++MH                KE  G+
Sbjct: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMH-------------RAGKEAGGA 107

Query: 121 GSYEYPVAEKAELSCWEEGNGRIALQG-TLLNTYVCSILIRTTMEVGFIVGQYFIYGIFL 179
            +         E  C        AL+       Y+ S+ +R   E+ F+ GQ  +YG  +
Sbjct: 108 EAAAQCAPGLPEAQC-----APCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRV 162

Query: 180 TTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWK 232
                C   PCPH V+C+VSRPTEK VF++F  AV  LS LLS+AEL HL WK
Sbjct: 163 APHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWK 215


>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
          Length = 273

 Score =  174 bits (441), Expect = 1e-43
 Identities = 98/265 (36%), Positives = 149/265 (56%), Gaps = 34/265 (12%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           +WS     L  V+K+ST  G++WL+++FIFR+LV    AE  W D+  DF C+T QPGC 
Sbjct: 2   NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           NVC+D+ FP+SH+R W LQ+I V+ PSL+ + H  +   +QEKR        +E  G   
Sbjct: 62  NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR-EVQEKRH-------REAHG--- 110

Query: 123 YEYPVAEKAELSCWEEGNGRIAL-----QGTLLNTYVCSILIRTTMEVGFI-VGQYFIYG 176
                          E +GR+ L     +G L  TYVCS++ + ++++ F+ V   F   
Sbjct: 111 ---------------ENSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPK 155

Query: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
             L  +  C   PCP+ V+C++S+P+EKN+F +FM+A AA+ +LL+L EL +L  K+  +
Sbjct: 156 YILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHE 215

Query: 237 RFVKPRQHMAKCQLSGPSVGIVQSC 261
             +  R+  A C    P  G   SC
Sbjct: 216 -CLAARKAQAMCTGHHPH-GTTSSC 238


>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
          Length = 223

 Score =  164 bits (415), Expect = 1e-40
 Identities = 87/227 (38%), Positives = 130/227 (57%), Gaps = 29/227 (12%)

Query: 4   WSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQN 63
           W FL + L  V+K+ST  G +WL V+F+FR+LV   AAE  W DEQ +F C++ QPGC+N
Sbjct: 3   WMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCKN 62

Query: 64  VCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGSY 123
           VC+D  FPIS +R W LQ+I VSTPSL+ + H    V   E R+ R  ++     G+   
Sbjct: 63  VCFDDFFPISQVRLWALQLIMVSTPSLLVVLH----VAYHEGREKRHRKKLYVSPGT--- 115

Query: 124 EYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTTL 182
                                + G L   Y+ S++++T  E+GF+V  Y +Y G  +  L
Sbjct: 116 ---------------------MDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYL 154

Query: 183 HVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
             C   PCP+ V+C++S+PTEK +FI+F++  + L ++L+  EL  L
Sbjct: 155 IKCDLKPCPNTVDCFISKPTEKTIFILFLVITSCLCIVLNFIELSFL 201


>gi|54607056 connexin 31 [Homo sapiens]
          Length = 270

 Score =  161 bits (408), Expect = 7e-40
 Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 23/229 (10%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           DW  L   L  V+K+ST  G++WL+V+F+FR+LV   AAE  WGDEQ DF C+T QPGC 
Sbjct: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           NVCYD  FPIS+IR W LQ+IFV+ PSL+ + H  +    + + + +  ++  ++  +  
Sbjct: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAG 121

Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFI-YGIFLTT 181
            ++                     G L  TY+ S++ +  +E  F+   + + +G  +  
Sbjct: 122 KKH---------------------GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPR 160

Query: 182 LHVCRR-SPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
           L  C   +PCP+ V+CY++RPTEK +F  FM+  +A+ ++L++ EL +L
Sbjct: 161 LVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209


>gi|13128960 connexin 31 [Homo sapiens]
          Length = 270

 Score =  161 bits (408), Expect = 7e-40
 Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 23/229 (10%)

Query: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
           DW  L   L  V+K+ST  G++WL+V+F+FR+LV   AAE  WGDEQ DF C+T QPGC 
Sbjct: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61

Query: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
           NVCYD  FPIS+IR W LQ+IFV+ PSL+ + H  +    + + + +  ++  ++  +  
Sbjct: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAG 121

Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFI-YGIFLTT 181
            ++                     G L  TY+ S++ +  +E  F+   + + +G  +  
Sbjct: 122 KKH---------------------GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPR 160

Query: 182 LHVCRR-SPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
           L  C   +PCP+ V+CY++RPTEK +F  FM+  +A+ ++L++ EL +L
Sbjct: 161 LVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209


>gi|145699105 connexin40.1 [Homo sapiens]
          Length = 370

 Score =  144 bits (362), Expect = 2e-34
 Identities = 81/232 (34%), Positives = 123/232 (53%), Gaps = 12/232 (5%)

Query: 7   LGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCY 66
           LG  +  ++ + T+VGK+W  +  + RMLV+  A    + DEQ  F C+T+QPGC NVCY
Sbjct: 7   LGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCY 66

Query: 67  DQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKE-VRGSGSYEY 125
           D   P+SH+R+W++Q + V  PS V+  + +H          R     +E   G      
Sbjct: 67  DVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPR 126

Query: 126 PVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVC 185
           P  E+  L   +   G           Y+  +L+RT +E  F    YF++G        C
Sbjct: 127 PFGERGGLQVPDFSAG-----------YIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPC 175

Query: 186 RRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQR 237
            R PC   V+CYVSRPTEK++ ++F+ AV+ALS LL LA+L     +++R+R
Sbjct: 176 TRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRR 227


>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
          Length = 279

 Score =  135 bits (341), Expect = 4e-32
 Identities = 78/225 (34%), Positives = 116/225 (51%), Gaps = 15/225 (6%)

Query: 6   FLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVC 65
           FL   L E  + ST VG++ L VL  FR+++L  +    +GDEQ++F C T QPGC+  C
Sbjct: 5   FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64

Query: 66  YDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGSYEY 125
           +D   P+S +R+WV Q+I V+ PS +YMG  ++ V               E+ G G  E 
Sbjct: 65  FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWH-----------WELSGKGKEEE 113

Query: 126 PVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVC 185
            + +  E +    G G +     LL  YV  +  R  +E   +  QY +YG  + +   C
Sbjct: 114 TLIQGREGNTDVPGAGSL----RLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFAC 169

Query: 186 RRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLG 230
           RR PC   + C +SRP+EK +F+  M  V+   LL +  EL  LG
Sbjct: 170 RREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLG 214


>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 38/85 (44%), Positives = 57/85 (67%)

Query: 11  LEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCYDQAF 70
           L E   HST VG++   VL  FR+++L  +    +GDEQ++F C T QPGC+  C+D   
Sbjct: 29  LAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 88

Query: 71  PISHIRYWVLQIIFVSTPSLVYMGH 95
           P+S +R+WV Q+I V+ PS++YMG+
Sbjct: 89  PLSPLRFWVFQVILVAVPSVLYMGY 113


>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 38/85 (44%), Positives = 57/85 (67%)

Query: 11  LEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCYDQAF 70
           L E   HST VG++   VL  FR+++L  +    +GDEQ++F C T QPGC+  C+D   
Sbjct: 29  LAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 88

Query: 71  PISHIRYWVLQIIFVSTPSLVYMGH 95
           P+S +R+WV Q+I V+ PS++YMG+
Sbjct: 89  PLSPLRFWVFQVILVAVPSVLYMGY 113


>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 38/85 (44%), Positives = 57/85 (67%)

Query: 11  LEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCYDQAF 70
           L E   HST VG++   VL  FR+++L  +    +GDEQ++F C T QPGC+  C+D   
Sbjct: 29  LAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 88

Query: 71  PISHIRYWVLQIIFVSTPSLVYMGH 95
           P+S +R+WV Q+I V+ PS++YMG+
Sbjct: 89  PLSPLRFWVFQVILVAVPSVLYMGY 113


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,366,738
Number of Sequences: 37866
Number of extensions: 720685
Number of successful extensions: 1677
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1604
Number of HSP's gapped (non-prelim): 50
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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