BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|32307175 KIAA1737 protein [Homo sapiens] (399 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|32307175 KIAA1737 protein [Homo sapiens] 786 0.0 gi|236459851 ubinuclein 2 [Homo sapiens] 42 7e-04 gi|222418647 mucin 7, secreted precursor [Homo sapiens] 42 0.001 gi|222418649 mucin 7, secreted precursor [Homo sapiens] 42 0.001 gi|222418645 mucin 7, secreted precursor [Homo sapiens] 42 0.001 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 42 0.001 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 42 0.001 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 41 0.002 gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 41 0.002 gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 40 0.003 gi|22547121 tumor necrosis factor receptor superfamily, member 1... 40 0.004 gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 40 0.004 gi|41281612 zinc finger protein 828 [Homo sapiens] 40 0.004 gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 39 0.006 gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 39 0.006 gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 39 0.006 gi|39995080 hypothetical protein LOC79567 [Homo sapiens] 39 0.006 gi|167466190 forkhead box P3 isoform b [Homo sapiens] 39 0.008 gi|31982943 forkhead box P3 isoform a [Homo sapiens] 39 0.008 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 39 0.011 gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens] 39 0.011 gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens] 39 0.011 gi|4758532 ral guanine nucleotide dissociation stimulator-like 2... 39 0.011 gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens] 38 0.014 gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 38 0.014 gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 38 0.014 gi|154090979 hypothetical protein LOC57481 [Homo sapiens] 38 0.014 gi|15147240 brother of CDO [Homo sapiens] 38 0.014 gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 38 0.018 gi|216547801 SH2 domain containing 3C isoform e [Homo sapiens] 38 0.018 >gi|32307175 KIAA1737 protein [Homo sapiens] Length = 399 Score = 786 bits (2031), Expect = 0.0 Identities = 399/399 (100%), Positives = 399/399 (100%) Query: 1 MERKNPSRESPRRLSAKVGKGTEMKKVARQLGMAAAESDKDSGFSDGSSECLSSAEQMES 60 MERKNPSRESPRRLSAKVGKGTEMKKVARQLGMAAAESDKDSGFSDGSSECLSSAEQMES Sbjct: 1 MERKNPSRESPRRLSAKVGKGTEMKKVARQLGMAAAESDKDSGFSDGSSECLSSAEQMES 60 Query: 61 EDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEV 120 EDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEV Sbjct: 61 EDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEV 120 Query: 121 ISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKG 180 ISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKG Sbjct: 121 ISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKG 180 Query: 181 TSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSP 240 TSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSP Sbjct: 181 TSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSP 240 Query: 241 QTLQPVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSSPLWAAEHLC 300 QTLQPVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSSPLWAAEHLC Sbjct: 241 QTLQPVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSSPLWAAEHLC 300 Query: 301 RSPDIFSEQRQSKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQVELDQLKEQTQLF 360 RSPDIFSEQRQSKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQVELDQLKEQTQLF Sbjct: 301 RSPDIFSEQRQSKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQVELDQLKEQTQLF 360 Query: 361 IEATKSRAPQAWAKLQASLTPGSSNTGSDLEAFSDHPAI 399 IEATKSRAPQAWAKLQASLTPGSSNTGSDLEAFSDHPAI Sbjct: 361 IEATKSRAPQAWAKLQASLTPGSSNTGSDLEAFSDHPAI 399 >gi|236459851 ubinuclein 2 [Homo sapiens] Length = 1347 Score = 42.4 bits (98), Expect = 7e-04 Identities = 53/171 (30%), Positives = 71/171 (41%), Gaps = 14/171 (8%) Query: 79 SKTAKNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEVISAQPQLLFLHPPVPS-- 136 SK+ PT+SP N LV QGS SS QPS IS Q L L P + Sbjct: 1077 SKSNPTPKPTVSPSSSSPNALVAQGSHSSTNSPVHKQPSGMNISRQSPTLNLLPSSRTSG 1136 Query: 137 --PVSPCHTGEKKSDSRNYLPI-LNSYTKIAPH-PGKRGLSLGPEEKGTSGVQKKICTER 192 P K ++S + + NS + IA + P RG +L +SG + + Sbjct: 1137 LPPTKNLQAPSKLTNSSSTGTVGKNSLSGIAMNVPASRGSNL-----NSSGANRTSLSGG 1191 Query: 193 LGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTL 243 G + TK + P PST + S A + G SL+A SP TL Sbjct: 1192 TGSGTQGA--TKPLSTPHRPSTASGSSVVTASVQSTAGA-SLLANASPLTL 1239 >gi|222418647 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 42.0 bits (97), Expect = 0.001 Identities = 55/217 (25%), Positives = 84/217 (38%), Gaps = 21/217 (9%) Query: 44 FSDGSSECLSSAEQMESEDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQG 103 F ++ +SS E + + ++ L + + P TA P+ + + + Sbjct: 131 FLPQNATTISSRENVNTSSSVATL--APVNSPAPQDTTAAPPTPSATTPAPPSSSAPPET 188 Query: 104 SSSSQLQSWTVQ--PSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYT 161 +++ S T Q PS S+ P PP P +P P S T Sbjct: 189 TAAPPTPSATTQAPPS----SSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSAT 244 Query: 162 KIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPS--TPAPPS 219 AP S PE T+ V L PS S+S P + A P +PS TPAPPS Sbjct: 245 TPAPLSS----SAPPE---TTAVPPTPSATTLDPS-SASAPPETTAAPPTPSATTPAPPS 296 Query: 220 AKLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPS 256 + +++ P SP TL P +S + AP+ Sbjct: 297 SPAPQETT--AAPITTPNSSPTTLAP-DTSETSAAPT 330 Score = 37.4 bits (85), Expect = 0.024 Identities = 45/179 (25%), Positives = 69/179 (38%), Gaps = 15/179 (8%) Query: 105 SSSQLQSWTVQPSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSY---- 160 +++Q+ S T + I+ P + FL P + +S S P+ + Sbjct: 107 ATTQIPSVTFPSASTKITTLPNVTFL-PQNATTISSRENVNTSSSVATLAPVNSPAPQDT 165 Query: 161 -----TKIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPST- 214 T A P S PE T+ T + PS SS+ P A P+ P+T Sbjct: 166 TAAPPTPSATTPAPPSSSAPPET--TAAPPTPSATTQAPPS-SSAPPETTAAPPTPPATT 222 Query: 215 PAPPSAKLA-EDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPSLTFASPASPVCASDST 272 PAPPS+ E +A PS + P ++ V PS T P+S ++T Sbjct: 223 PAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETT 281 Score = 37.0 bits (84), Expect = 0.031 Identities = 43/178 (24%), Positives = 61/178 (34%), Gaps = 28/178 (15%) Query: 120 VISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEK 179 V S PQ PP PS +P P S T AP S P Sbjct: 157 VNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPS-----SSAP--- 208 Query: 180 GTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGS 239 P +++ PT P+ PS+ APP A + P+ ++ + Sbjct: 209 ---------------PETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSA 253 Query: 240 P--QTLQPVSSSHVAKAPSLTFASP---ASPVCASDSTLHGLESNSPLSPLSANYSSP 292 P T P + S PS A P A+P S +T S +P +A ++P Sbjct: 254 PPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTP 311 >gi|222418649 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 42.0 bits (97), Expect = 0.001 Identities = 55/217 (25%), Positives = 84/217 (38%), Gaps = 21/217 (9%) Query: 44 FSDGSSECLSSAEQMESEDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQG 103 F ++ +SS E + + ++ L + + P TA P+ + + + Sbjct: 131 FLPQNATTISSRENVNTSSSVATL--APVNSPAPQDTTAAPPTPSATTPAPPSSSAPPET 188 Query: 104 SSSSQLQSWTVQ--PSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYT 161 +++ S T Q PS S+ P PP P +P P S T Sbjct: 189 TAAPPTPSATTQAPPS----SSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSAT 244 Query: 162 KIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPS--TPAPPS 219 AP S PE T+ V L PS S+S P + A P +PS TPAPPS Sbjct: 245 TPAPLSS----SAPPE---TTAVPPTPSATTLDPS-SASAPPETTAAPPTPSATTPAPPS 296 Query: 220 AKLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPS 256 + +++ P SP TL P +S + AP+ Sbjct: 297 SPAPQETT--AAPITTPNSSPTTLAP-DTSETSAAPT 330 Score = 37.4 bits (85), Expect = 0.024 Identities = 45/179 (25%), Positives = 69/179 (38%), Gaps = 15/179 (8%) Query: 105 SSSQLQSWTVQPSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSY---- 160 +++Q+ S T + I+ P + FL P + +S S P+ + Sbjct: 107 ATTQIPSVTFPSASTKITTLPNVTFL-PQNATTISSRENVNTSSSVATLAPVNSPAPQDT 165 Query: 161 -----TKIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPST- 214 T A P S PE T+ T + PS SS+ P A P+ P+T Sbjct: 166 TAAPPTPSATTPAPPSSSAPPET--TAAPPTPSATTQAPPS-SSAPPETTAAPPTPPATT 222 Query: 215 PAPPSAKLA-EDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPSLTFASPASPVCASDST 272 PAPPS+ E +A PS + P ++ V PS T P+S ++T Sbjct: 223 PAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETT 281 Score = 37.0 bits (84), Expect = 0.031 Identities = 43/178 (24%), Positives = 61/178 (34%), Gaps = 28/178 (15%) Query: 120 VISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEK 179 V S PQ PP PS +P P S T AP S P Sbjct: 157 VNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPS-----SSAP--- 208 Query: 180 GTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGS 239 P +++ PT P+ PS+ APP A + P+ ++ + Sbjct: 209 ---------------PETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSA 253 Query: 240 P--QTLQPVSSSHVAKAPSLTFASP---ASPVCASDSTLHGLESNSPLSPLSANYSSP 292 P T P + S PS A P A+P S +T S +P +A ++P Sbjct: 254 PPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTP 311 >gi|222418645 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 42.0 bits (97), Expect = 0.001 Identities = 55/217 (25%), Positives = 84/217 (38%), Gaps = 21/217 (9%) Query: 44 FSDGSSECLSSAEQMESEDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQG 103 F ++ +SS E + + ++ L + + P TA P+ + + + Sbjct: 131 FLPQNATTISSRENVNTSSSVATL--APVNSPAPQDTTAAPPTPSATTPAPPSSSAPPET 188 Query: 104 SSSSQLQSWTVQ--PSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYT 161 +++ S T Q PS S+ P PP P +P P S T Sbjct: 189 TAAPPTPSATTQAPPS----SSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSAT 244 Query: 162 KIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPS--TPAPPS 219 AP S PE T+ V L PS S+S P + A P +PS TPAPPS Sbjct: 245 TPAPLSS----SAPPE---TTAVPPTPSATTLDPS-SASAPPETTAAPPTPSATTPAPPS 296 Query: 220 AKLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPS 256 + +++ P SP TL P +S + AP+ Sbjct: 297 SPAPQETT--AAPITTPNSSPTTLAP-DTSETSAAPT 330 Score = 37.4 bits (85), Expect = 0.024 Identities = 45/179 (25%), Positives = 69/179 (38%), Gaps = 15/179 (8%) Query: 105 SSSQLQSWTVQPSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSY---- 160 +++Q+ S T + I+ P + FL P + +S S P+ + Sbjct: 107 ATTQIPSVTFPSASTKITTLPNVTFL-PQNATTISSRENVNTSSSVATLAPVNSPAPQDT 165 Query: 161 -----TKIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPST- 214 T A P S PE T+ T + PS SS+ P A P+ P+T Sbjct: 166 TAAPPTPSATTPAPPSSSAPPET--TAAPPTPSATTQAPPS-SSAPPETTAAPPTPPATT 222 Query: 215 PAPPSAKLA-EDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPSLTFASPASPVCASDST 272 PAPPS+ E +A PS + P ++ V PS T P+S ++T Sbjct: 223 PAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETT 281 Score = 37.0 bits (84), Expect = 0.031 Identities = 43/178 (24%), Positives = 61/178 (34%), Gaps = 28/178 (15%) Query: 120 VISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEK 179 V S PQ PP PS +P P S T AP S P Sbjct: 157 VNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPS-----SSAP--- 208 Query: 180 GTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGS 239 P +++ PT P+ PS+ APP A + P+ ++ + Sbjct: 209 ---------------PETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSA 253 Query: 240 P--QTLQPVSSSHVAKAPSLTFASP---ASPVCASDSTLHGLESNSPLSPLSANYSSP 292 P T P + S PS A P A+P S +T S +P +A ++P Sbjct: 254 PPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTP 311 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 41.6 bits (96), Expect = 0.001 Identities = 63/332 (18%), Positives = 118/332 (35%), Gaps = 45/332 (13%) Query: 4 KNPSRESPRRLSAKVGKGT-EMKKVARQLGMAAAESDKDSGFSDGSSECLSSAEQMESED 62 K+ ++ SP+ + K K E +++ + + +E+ + S S SS + + S++ Sbjct: 89 KSTTKRSPKPPNKKKTKKVIESEEITEE--HSVSENQESSSSSSSSSSSSTIRKIKSSKN 146 Query: 63 MLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEVIS 122 + ++ + + N K PT P VV + T +S Sbjct: 147 SAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVS 206 Query: 123 AQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEE---- 178 P++ P P P P ++ K S TK K+ + G E+ Sbjct: 207 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 266 Query: 179 KGTSGVQK------------------KICTERLGPSLSSSE------------------- 201 K T ++K K T GP+L++ + Sbjct: 267 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 326 Query: 202 PTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQT-LQPVSSSHVAKAPSLTFA 260 PT + P++P PAP + K A + + P+ +P T +P ++ AP+ T + Sbjct: 327 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 386 Query: 261 SPASPVCASDSTLHGLESNSPLSPLSANYSSP 292 +P +P + +T +P P P Sbjct: 387 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418 Score = 34.7 bits (78), Expect = 0.16 Identities = 34/168 (20%), Positives = 62/168 (36%), Gaps = 7/168 (4%) Query: 132 PPVPSPVS---PCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKI 188 P P+P + P T K + + P + K AP K P+E + ++ Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 427 Query: 189 CTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSA----LQGVPSLVAGGSPQTLQ 244 T + + EP +P+TP P+ ++ A + P+ +P T + Sbjct: 428 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 487 Query: 245 PVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSSP 292 ++ AP+ T ++P +P S +T +P P P Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 535 Score = 32.0 bits (71), Expect = 1.0 Identities = 32/164 (19%), Positives = 63/164 (38%), Gaps = 4/164 (2%) Query: 132 PPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKICTE 191 P +P P T K+ P + + AP K+ P+E + ++ T Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469 Query: 192 RLGPSLSSSE---PTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSS 248 PS ++ + PT + P++ PAP + K A + + P+ +P T + + Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529 Query: 249 SHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSSP 292 + K P+ T +P + + +P +P ++P Sbjct: 530 T-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572 Score = 31.6 bits (70), Expect = 1.3 Identities = 40/177 (22%), Positives = 66/177 (37%), Gaps = 24/177 (13%) Query: 132 PPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKICTE 191 P P+P +P T + + P + K+AP ++ PEE + ++ T Sbjct: 564 PKEPAPTTPKETAP--TTPKKLTP--TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 619 Query: 192 RLGPSLSSSEPTKAGAVPSSPSTPAPPSAK---------LAEDSALQGVPSLVAGGSPQT 242 P+ + T A P++P PAP + K A + + P+ G +P T Sbjct: 620 PEEPAPT----TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 675 Query: 243 L-QPVSSSHVAKAPS----LTFASPASPVC--ASDSTLHGLESNSPLSPLSANYSSP 292 L +P ++ AP T P S C + +T G +P P P Sbjct: 676 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP 732 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 41.6 bits (96), Expect = 0.001 Identities = 63/332 (18%), Positives = 118/332 (35%), Gaps = 45/332 (13%) Query: 4 KNPSRESPRRLSAKVGKGT-EMKKVARQLGMAAAESDKDSGFSDGSSECLSSAEQMESED 62 K+ ++ SP+ + K K E +++ + + +E+ + S S SS + + S++ Sbjct: 130 KSTTKRSPKPPNKKKTKKVIESEEITEE--HSVSENQESSSSSSSSSSSSTIRKIKSSKN 187 Query: 63 MLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEVIS 122 + ++ + + N K PT P VV + T +S Sbjct: 188 SAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVS 247 Query: 123 AQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEE---- 178 P++ P P P P ++ K S TK K+ + G E+ Sbjct: 248 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 307 Query: 179 KGTSGVQK------------------KICTERLGPSLSSSE------------------- 201 K T ++K K T GP+L++ + Sbjct: 308 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 367 Query: 202 PTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQT-LQPVSSSHVAKAPSLTFA 260 PT + P++P PAP + K A + + P+ +P T +P ++ AP+ T + Sbjct: 368 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 427 Query: 261 SPASPVCASDSTLHGLESNSPLSPLSANYSSP 292 +P +P + +T +P P P Sbjct: 428 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459 Score = 34.7 bits (78), Expect = 0.16 Identities = 34/168 (20%), Positives = 62/168 (36%), Gaps = 7/168 (4%) Query: 132 PPVPSPVS---PCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKI 188 P P+P + P T K + + P + K AP K P+E + ++ Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 468 Query: 189 CTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSA----LQGVPSLVAGGSPQTLQ 244 T + + EP +P+TP P+ ++ A + P+ +P T + Sbjct: 469 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 528 Query: 245 PVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSSP 292 ++ AP+ T ++P +P S +T +P P P Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 576 Score = 32.0 bits (71), Expect = 1.0 Identities = 32/164 (19%), Positives = 63/164 (38%), Gaps = 4/164 (2%) Query: 132 PPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKICTE 191 P +P P T K+ P + + AP K+ P+E + ++ T Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510 Query: 192 RLGPSLSSSE---PTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSS 248 PS ++ + PT + P++ PAP + K A + + P+ +P T + + Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570 Query: 249 SHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSSP 292 + K P+ T +P + + +P +P ++P Sbjct: 571 T-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613 Score = 31.6 bits (70), Expect = 1.3 Identities = 40/177 (22%), Positives = 66/177 (37%), Gaps = 24/177 (13%) Query: 132 PPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKICTE 191 P P+P +P T + + P + K+AP ++ PEE + ++ T Sbjct: 605 PKEPAPTTPKETAP--TTPKKLTP--TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 660 Query: 192 RLGPSLSSSEPTKAGAVPSSPSTPAPPSAK---------LAEDSALQGVPSLVAGGSPQT 242 P+ + T A P++P PAP + K A + + P+ G +P T Sbjct: 661 PEEPAPT----TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 716 Query: 243 L-QPVSSSHVAKAPS----LTFASPASPVC--ASDSTLHGLESNSPLSPLSANYSSP 292 L +P ++ AP T P S C + +T G +P P P Sbjct: 717 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP 773 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 41.2 bits (95), Expect = 0.002 Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 8/101 (7%) Query: 190 TERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSSS 249 T +L P + + T SS S P SA L ++ VP+ + P TL PV +S Sbjct: 1722 TSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSAS-VPASTSAPLPATLTPVPAS 1780 Query: 250 HVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYS 290 A P+ T A PV AS S SPL+P+SA+ S Sbjct: 1781 TSAPVPASTLA----PVLASTS---APVPASPLAPVSASAS 1814 Score = 36.6 bits (83), Expect = 0.041 Identities = 57/211 (27%), Positives = 85/211 (40%), Gaps = 22/211 (10%) Query: 96 KNVLVKQGSSSSQL-------QSWTVQPSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKS 148 KN K S +S+L Q+ +Q + S P PP S P T Sbjct: 1712 KNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLP 1771 Query: 149 DSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGV--QKKICTERLGPSLSSSEP--TK 204 + +P S AP P +L P TS + S+S+S P T Sbjct: 1772 ATLTPVPASTS----APVPAS---TLAPVLASTSAPVPASPLAPVSASASVSASVPASTS 1824 Query: 205 AGAVPSS--PSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPSLTFASP 262 A A+ SS P++ P+ LA S V +++A S L +S A P+ +SP Sbjct: 1825 AAAITSSSAPASAPAPTPILASVSTPASV-TILASASIPILASALASTSAPTPAPAASSP 1883 Query: 263 ASPVCASDSTLHGLESNS-PLSPLSANYSSP 292 A+PV + + + S PL+P SA+ +P Sbjct: 1884 AAPVITAPTIPASAPTASVPLAPASASAPAP 1914 >gi|58530876 melanoma antigen family C, 1 [Homo sapiens] Length = 1142 Score = 40.8 bits (94), Expect = 0.002 Identities = 54/223 (24%), Positives = 92/223 (41%), Gaps = 26/223 (11%) Query: 75 PRQNSKTAKNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEVISAQPQLLFLHPPV 134 P Q+ ++A +LSP+ + ++ L + S SS + P+ P+ Sbjct: 675 PLQSPESAPEGEDSLSPLQIPQSPLEGEDSLSS----------LHFPQSPPEWEDSLSPL 724 Query: 135 PSPVSPCHTGEKKSDSRNYLPILNSYTKIA-PHPGKRGLSLGPEEKGTSGVQKKICT--- 190 P P + +S ++ + I +S T ++ P PE S +Q+ + + Sbjct: 725 HFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQRPVSSFFS 784 Query: 191 ERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSSSH 250 L L SS SP +P A+ S + PS + Q+ PVSS Sbjct: 785 YTLASLLQSSH--------ESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQS-SPVSSFP 835 Query: 251 VAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSSPL 293 + + SL+ +SP SP+ S + S++ LSP S SSP+ Sbjct: 836 SSTSSSLSKSSPESPL---QSPVISFSSSTSLSPFSEESSSPV 875 >gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 490 Score = 40.4 bits (93), Expect = 0.003 Identities = 48/170 (28%), Positives = 68/170 (40%), Gaps = 31/170 (18%) Query: 114 VQPSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPH------- 166 V P F ++S L+ LH PV SP P + S +Y + Y+ ++PH Sbjct: 38 VSPHFPLVSPHHPLVSLHHPV-SPHFPLVSPHHPLMSPHYSLVSPQYSPVSPHCPLVSPH 96 Query: 167 ------------PGKRGLSLGPEE-----KGTSGVQKKICTERLG-PSLSSSEPTKAGAV 208 P G+ P + G + + + PSL S P+ V Sbjct: 97 YSLVSPHRPLVSPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGV 156 Query: 209 PSSPS-TPAPPSAKLAEDSALQGVPSLVAG-GSPQTLQPVSSSHVAKAPS 256 PS PS P+PPS + S VPSL++G SP + P S V PS Sbjct: 157 PSPPSDVPSPPSDVPSPPS---DVPSLLSGVPSPPSDVPSPPSDVPSPPS 203 Score = 34.7 bits (78), Expect = 0.16 Identities = 55/178 (30%), Positives = 69/178 (38%), Gaps = 30/178 (16%) Query: 132 PP--VPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKIC 189 PP VPSP S + +P+L+ P P SL + SGV Sbjct: 194 PPSDVPSPPSDVPLLSDVPSPPSDVPLLSD----VPSPPSDVPSLPSDVPSLSGV----- 244 Query: 190 TERLGPSLSSSEPTKAGAVPSSPSTPAPPS--AKLAED--SALQGVPSLVAG-GSPQTLQ 244 PS S P+ VPS PS +PPS L D S VPSL++G SP + Sbjct: 245 -----PSPPSDVPSLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDV 299 Query: 245 PVSSSHVAKAPSLTFASPAS-------PVCASDSTLHGLESNSPLS--PLSANYSSPL 293 P S V PS + P+ P SD + SP S PL + SPL Sbjct: 300 PSLLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSGVPSPL 357 Score = 31.6 bits (70), Expect = 1.3 Identities = 25/55 (45%), Positives = 28/55 (50%), Gaps = 10/55 (18%) Query: 195 PSLSSSEPTKAGAVPSSPS-TPAPPSAKLAEDSALQGVPSLVAG-----GSPQTL 243 PSL S P+ VPSSPS P+ PS L GVPSL +G G P TL Sbjct: 399 PSLLSDVPSLLSGVPSSPSGVPSLPSGV----PILSGVPSLPSGVPSPSGVPITL 449 Score = 30.4 bits (67), Expect = 2.9 Identities = 40/98 (40%), Positives = 46/98 (46%), Gaps = 12/98 (12%) Query: 195 PSLSSSEPTKAGAVPSSPS-TPAPPS-AKLAED--SALQGVPSLVAGGSPQTLQPVSSSH 250 PSL S P+ VPS PS P+PPS L D S VP L SP + P S Sbjct: 178 PSLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSD 237 Query: 251 VAKAPSLT-FASPASPVCASDSTLHGLES-NSPLSPLS 286 V PSL+ SP S V S L G+ S S +SP S Sbjct: 238 V---PSLSGVPSPPSDV---PSLLSGVPSPPSDISPPS 269 >gi|22547121 tumor necrosis factor receptor superfamily, member 10c precursor [Homo sapiens] Length = 259 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 9/103 (8%) Query: 189 CTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSS 248 C E G + + P + +SP TPAP A + + P A + +T+ Sbjct: 149 CVEEFGANATVETPAAEETMNTSPGTPAP-----AAEETMNTSPGTPAPAAEETMTTSPG 203 Query: 249 SHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSS 291 + A SP +P A++ T+ + SP +P S++Y S Sbjct: 204 TPAPAAEETMTTSPGTPAPAAEETM----TTSPGTPASSHYLS 242 >gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e [Homo sapiens] Length = 1451 Score = 40.0 bits (92), Expect = 0.004 Identities = 77/345 (22%), Positives = 118/345 (34%), Gaps = 36/345 (10%) Query: 49 SECLSSAEQMESEDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQGSSSSQ 108 S SS+ + E ED++ A R N T A P ++P M + SS Sbjct: 992 STARSSSSESEDEDVIPATQCLTPGI-RTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 1050 Query: 109 LQSWTVQPSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRN-YLPILNSYTKIAPHP 167 P+ +V SA L P SP S + + R LP + TK AP Sbjct: 1051 DGKKQEGPATQVDSAVGTL-----PATSPQSTSVQAKGTNKLRKPKLPEVQQATK-APES 1104 Query: 168 G-----KRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSA-K 221 S G EE G GP + S T G PS T +A + Sbjct: 1105 SDDSEDSSDSSSGSEEDGE------------GPQGAKSAHTLVGPTPSRTETLVEETAAE 1152 Query: 222 LAEDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSP 281 +ED + SL++G L P +S P L + S A+ G + P Sbjct: 1153 SSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKP 1212 Query: 282 ------LSPLSANYSSPLWAAEHLCRSPDIFSEQRQSKHRRFQNTLVVLHKSGLLEITLK 335 LSP + + R P + Q+ Q+ + LL Sbjct: 1213 QQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT----QCLLGQPWP 1268 Query: 336 TKELIRQNQATQVELDQLKEQTQLFIEATKSRAPQAWAKLQASLT 380 E Q +V + L+++ + ++ TK + + W + L+ Sbjct: 1269 LNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS 1313 Score = 34.3 bits (77), Expect = 0.20 Identities = 62/254 (24%), Positives = 94/254 (37%), Gaps = 30/254 (11%) Query: 6 PSRESPRRLSAKVGKGTEMKKVAR-QLGMAAAESDKDSGFSDGSSECLSSAEQMESEDML 64 P++ESPR+ +A G VA+ Q G +S S SD E + A+ + Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436 Query: 65 SALGWSREDRPRQNSKTA--KNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEVIS 122 A ++ PR+ + A + P + + V K ++ S SS +S + + + ++ Sbjct: 437 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ---EEDSRSSSEESDSDREALAAMN 493 Query: 123 AQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTS 182 A P P S G L P PGK +GP T Sbjct: 494 AAQVKPLGKSPQVKPASTMGMGP-----------LGKGAGPVP-PGK----VGP---ATP 534 Query: 183 GVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVP-SLVAGGSPQ 241 Q E S S + G VP T P+ + + + LQ P S A G PQ Sbjct: 535 SAQVGKWEEDSESSSEESSDSSDGEVP----TAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590 Query: 242 TLQPVSSSHVAKAP 255 PV+ A+ P Sbjct: 591 KAGPVAVQVKAEKP 604 >gi|41281612 zinc finger protein 828 [Homo sapiens] Length = 812 Score = 40.0 bits (92), Expect = 0.004 Identities = 58/185 (31%), Positives = 81/185 (43%), Gaps = 41/185 (22%) Query: 132 PPVPSPVS-PCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGV-----Q 185 PP+P PC++ E KS +P L+ T+ K G L PE + + Q Sbjct: 109 PPLPEHQKIPCNSAEPKS-----IPALSMETQ------KLGSVLSPESPKPTPLTPLEPQ 157 Query: 186 K--KICTERLGPSLSSSEPTKAGAVPSSPSTPAPP-SAKLAEDSALQGVPS----LVAGG 238 K + + L L S EP+K P+S S+P PP S + E L VPS A Sbjct: 158 KPGSVVSPELQTPLPSPEPSK----PASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPV 213 Query: 239 SPQTL-------QPVSSSHVAKA---PSLTFASPASPVCASDSTLHG-LESNSPLSPLSA 287 SP+++ +P SH + PS +SP SPV A+ G + SP S SA Sbjct: 214 SPESVKATLSNPKPQKQSHFPETLGPPSA--SSPESPVLAASPEPWGPSPAASPESRKSA 271 Query: 288 NYSSP 292 +SP Sbjct: 272 RTTSP 276 >gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 39.3 bits (90), Expect = 0.006 Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 8/77 (10%) Query: 194 GPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAK 253 GP SEP +PS PST PP L E P +A P L+ +S H Sbjct: 149 GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPP----PPSMAPPPPPVLEALSPPHTLS 204 Query: 254 APSL----TFASPASPV 266 +PS+ F PA P+ Sbjct: 205 SPSIPTPPDFIPPAPPL 221 >gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 39.3 bits (90), Expect = 0.006 Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 8/77 (10%) Query: 194 GPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAK 253 GP SEP +PS PST PP L E P +A P L+ +S H Sbjct: 149 GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPP----PPSMAPPPPPVLEALSPPHTLS 204 Query: 254 APSL----TFASPASPV 266 +PS+ F PA P+ Sbjct: 205 SPSIPTPPDFIPPAPPL 221 >gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens] Length = 1188 Score = 39.3 bits (90), Expect = 0.006 Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 8/77 (10%) Query: 194 GPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAK 253 GP SEP +PS PST PP L E P +A P L+ +S H Sbjct: 149 GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPP----PPSMAPPPPPVLEALSPPHTLS 204 Query: 254 APSL----TFASPASPV 266 +PS+ F PA P+ Sbjct: 205 SPSIPTPPDFIPPAPPL 221 >gi|39995080 hypothetical protein LOC79567 [Homo sapiens] Length = 1219 Score = 39.3 bits (90), Expect = 0.006 Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 17/163 (10%) Query: 135 PSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKICTERL- 193 PSP++ TG + PI+++ T P +GP + TS Sbjct: 563 PSPLTHTTTGS------THKPIISTLTTTGPTLN----IIGPVQTTTSPTHTMPSPTHTT 612 Query: 194 -GPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQT--LQPVSSS- 249 P+ +S+ PT P+ ++ +PP+ S + V + + P T P +S Sbjct: 613 ASPTHTSTSPTHTPTSPTHKTSMSPPTTTSPTPSGMGLVQTATSPTHPTTSPTHPTTSPI 672 Query: 250 --HVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYS 290 +V+ + SL A+ +SP SD TL G +S P+S +Y+ Sbjct: 673 LINVSPSTSLELATLSSPSKHSDPTLPGTDSLPCSPPVSNSYT 715 Score = 30.0 bits (66), Expect = 3.8 Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 10/86 (11%) Query: 155 PILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPS-SPS 213 P+ NSYT+ P + P +K + + P+ SE T P+ SP Sbjct: 709 PVSNSYTQADPMAPRT-----PHPSPAHSSRKPLTS----PAPDPSESTVQSLSPTPSPP 759 Query: 214 TPAPPSAKLAEDSALQGVPSLVAGGS 239 TPAP + L A+Q AGGS Sbjct: 760 TPAPQHSDLCLAMAVQTPVPTAAGGS 785 >gi|167466190 forkhead box P3 isoform b [Homo sapiens] Length = 396 Score = 38.9 bits (89), Expect = 0.008 Identities = 52/177 (29%), Positives = 74/177 (41%), Gaps = 28/177 (15%) Query: 216 APPSAKLAEDSALQGVPSLVAG-GSPQTLQPVSSSHVAKAPSL--TFASPASPVCASDST 272 +P L + GV SL A G P + S V++ P+L TF +P++P DST Sbjct: 90 SPAMISLTPPTTATGVFSLKARPGLPPGINVASLEWVSREPALLCTFPNPSAP--RKDST 147 Query: 273 LHGLESNSPLSPLSANYSSPLWAAEHLCRSPDIFSEQRQSKHRRFQNTLVVLHKSGLLEI 332 L + +S PL AN E + P+ F + Q+ H +L + G + Sbjct: 148 LSAVPQSS--YPLLANGVCKWPGCEKVFEEPEDFLKHCQADH--------LLDEKGRAQC 197 Query: 333 TLKTKELIRQNQATQVELDQLKEQTQLFIEATKSRAPQAWAKLQASLTPGSSNTGSD 389 L Q E+ Q EQ QL +E K A QA + +LT SS SD Sbjct: 198 LL------------QREMVQSLEQ-QLVLEKEKLSAMQAHLAGKMALTKASSVASSD 241 >gi|31982943 forkhead box P3 isoform a [Homo sapiens] Length = 431 Score = 38.9 bits (89), Expect = 0.008 Identities = 52/177 (29%), Positives = 74/177 (41%), Gaps = 28/177 (15%) Query: 216 APPSAKLAEDSALQGVPSLVAG-GSPQTLQPVSSSHVAKAPSL--TFASPASPVCASDST 272 +P L + GV SL A G P + S V++ P+L TF +P++P DST Sbjct: 125 SPAMISLTPPTTATGVFSLKARPGLPPGINVASLEWVSREPALLCTFPNPSAP--RKDST 182 Query: 273 LHGLESNSPLSPLSANYSSPLWAAEHLCRSPDIFSEQRQSKHRRFQNTLVVLHKSGLLEI 332 L + +S PL AN E + P+ F + Q+ H +L + G + Sbjct: 183 LSAVPQSS--YPLLANGVCKWPGCEKVFEEPEDFLKHCQADH--------LLDEKGRAQC 232 Query: 333 TLKTKELIRQNQATQVELDQLKEQTQLFIEATKSRAPQAWAKLQASLTPGSSNTGSD 389 L Q E+ Q EQ QL +E K A QA + +LT SS SD Sbjct: 233 LL------------QREMVQSLEQ-QLVLEKEKLSAMQAHLAGKMALTKASSVASSD 276 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 38.5 bits (88), Expect = 0.011 Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 14/148 (9%) Query: 131 HPPVPSP-----VSPCHTGEKKSDSRNYLPILNSYTKIAPHP-GKRGLSLGPEEKGTSGV 184 HP P P + P + D+ L L+S P P G + + P + + + Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL 327 Query: 185 QKKICTERLGPSLSSS---EPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQ 241 T P L++ P A PS + P+PP+ ++ P + A S Q Sbjct: 328 P---ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384 Query: 242 TLQPVSSSHVAKAPSLTFASPASPVCAS 269 T+ P+ H +PSL +P SP+ S Sbjct: 385 TIPPIQVPHSLTSPSL--QAPPSPLALS 410 Score = 37.7 bits (86), Expect = 0.018 Identities = 84/341 (24%), Positives = 116/341 (34%), Gaps = 75/341 (21%) Query: 3 RKNPSRESPRRL--SAKVGKGTEMKKVARQLGMAAAESDKDSGFSDGSSECLSSAEQMES 60 R P E PR+ SA TE AR+ A + + S SS S+ Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256 Query: 61 EDMLSALGWSRED--------------RPRQNSKTAKNAFPTLSPMVVMKNVLVKQGSSS 106 SA G R RP Q + K+A P L P+ + L S Sbjct: 257 P---SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL--SSSPLATPSPSG 311 Query: 107 SQLQSWTVQPSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPH 166 ++ + V P + P L PP+ +P+ S LP Sbjct: 312 TKARP--VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP----------S 359 Query: 167 PGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPS----AKL 222 P S P T +Q PSL + P + +SPS APPS + L Sbjct: 360 PPATPPSQAPPSMTTPPMQAP-------PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL 412 Query: 223 AEDSALQGVPSLVAGGSPQTLQPVSS------------------------SHVAKAPSLT 258 ++L G P+L A S T+ P + S A P T Sbjct: 413 QATTSL-GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT 471 Query: 259 FASPASPVCASDSTLHGLE------SNSPLSPLSANYSSPL 293 SPA +S T+H L+ S+SP +PLS+ PL Sbjct: 472 SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512 Score = 31.2 bits (69), Expect = 1.7 Identities = 33/116 (28%), Positives = 49/116 (42%), Gaps = 19/116 (16%) Query: 189 CTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSS 248 C + PS ++ P + PSS +TP P + LQG+PS SP P + Sbjct: 567 CPLQAPPSPLTTPPPET---PSSIATPPPQAPPALASPPLQGLPSPPL--SPLATPPPQA 621 Query: 249 SHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSA-NYSSPLWAAEHLCRSP 303 P L +P SP ++ PLSPL+ + +P A HL ++P Sbjct: 622 PPXLALPPL--QAPPSP-----------PASPPLSPLATPSPQAPNALAVHLLQAP 664 >gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens] Length = 1290 Score = 38.5 bits (88), Expect = 0.011 Identities = 45/168 (26%), Positives = 63/168 (37%), Gaps = 45/168 (26%) Query: 194 GPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQG----------------------- 230 G EP + A P+ P PAPP + A DS L+ Sbjct: 442 GTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQLAQSRKQVAKKSTSFRPGSVGS 501 Query: 231 ------VPSL---VAGGSPQTLQ----PVSSSHVAKAPSLTFASPASPVCASDSTLHGLE 277 P+L V+GG P Q P+ S+ A APS A PA PV HG+ Sbjct: 502 GHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPSALPAPPAPPV------FHGML 555 Query: 278 SNSPLSPLSANYSSPLWAAEHLCRSPDIFSEQRQSKHRRF--QNTLVV 323 +P P L+ H+C S S R ++ ++ +N L+V Sbjct: 556 ERAPAEPSYRAPMEKLFYLPHVC-SYTCLSRVRPMRNEQYRGKNPLLV 602 >gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens] Length = 1291 Score = 38.5 bits (88), Expect = 0.011 Identities = 45/168 (26%), Positives = 63/168 (37%), Gaps = 45/168 (26%) Query: 194 GPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQG----------------------- 230 G EP + A P+ P PAPP + A DS L+ Sbjct: 442 GTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQLAQSRKQVAKKSTSFRPGSVGS 501 Query: 231 ------VPSL---VAGGSPQTLQ----PVSSSHVAKAPSLTFASPASPVCASDSTLHGLE 277 P+L V+GG P Q P+ S+ A APS A PA PV HG+ Sbjct: 502 GHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPSALPAPPAPPV------FHGML 555 Query: 278 SNSPLSPLSANYSSPLWAAEHLCRSPDIFSEQRQSKHRRF--QNTLVV 323 +P P L+ H+C S S R ++ ++ +N L+V Sbjct: 556 ERAPAEPSYRAPMEKLFYLPHVC-SYTCLSRVRPMRNEQYRGKNPLLV 602 >gi|4758532 ral guanine nucleotide dissociation stimulator-like 2 [Homo sapiens] Length = 777 Score = 38.5 bits (88), Expect = 0.011 Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 17/102 (16%) Query: 195 PSLSSSEPTKAGAVPSSPSTPAPPSAKLAE----------DSALQGVPSLVAGGSPQTLQ 244 P +S P+ G +P+TPAP +LA+ DSAL+ PSL + P L Sbjct: 545 PLVSCDRPSTGG--DEAPTTPAPLLTRLAQHMKWPSVSSLDSALESSPSLHSPADPSHLS 602 Query: 245 PVSSSHVAKAPSLTFASPASPVC-----ASDSTLHGLESNSP 281 P +SS AS SP+ AS T +G E + P Sbjct: 603 PPASSPRPSRGHRRSASCGSPLSGGAEEASGGTGYGGEGSGP 644 >gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens] Length = 829 Score = 38.1 bits (87), Expect = 0.014 Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 11/132 (8%) Query: 170 RGLSLGPEEKGTSGVQKKICTERLGP----SLSSSEPTKAGAVPSSPSTPAPPSAKLAED 225 +G S G + T+ QK+ C++ P + S E +A SSP P P ++K Sbjct: 460 KGPSYGEDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSP 519 Query: 226 SALQGVPSLVAGGSPQTLQPVSSSHVAKAPS-----LTFASPASPVCASDSTLHGLESNS 280 L G PS + + +S+HVA + S + A +S + +E+ Sbjct: 520 PHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAE 579 Query: 281 PLSPLSANYSSP 292 P S S +SSP Sbjct: 580 PQS--SPAHSSP 589 >gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo sapiens] Length = 834 Score = 38.1 bits (87), Expect = 0.014 Identities = 52/189 (27%), Positives = 70/189 (37%), Gaps = 39/189 (20%) Query: 81 TAKNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEVISAQPQLLFLHPPVPSPVSP 140 T + PT P + G S T+ S S+QP L F + P+ P Sbjct: 482 TFSQSLPTAVPTATSSSAADFSGFGS------TLATSAPATSSQPTLTFSNTSTPTFNIP 535 Query: 141 CHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSS 200 + K L SY P P + G E G K T PS SS Sbjct: 536 FGSSAKSP--------LPSYPGANPQP-----AFGAAEGQPPGAAKPALT----PSFGSS 578 Query: 201 EPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPV--SSSHVA---KAP 255 A P++ TPAPP S ++ VP+ V P +QP ++H A KA Sbjct: 579 FTFGNSAAPAAAPTPAPP-------SMIKIVPAHV----PTPIQPTFGGATHSAFGLKAT 627 Query: 256 SLTFASPAS 264 + F +PAS Sbjct: 628 ASAFGAPAS 636 Score = 35.0 bits (79), Expect = 0.12 Identities = 50/175 (28%), Positives = 70/175 (40%), Gaps = 20/175 (11%) Query: 124 QPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKG--T 181 QP F P +P SP + S + P+L S K+ P L PE G T Sbjct: 154 QPSFTFTLPAA-APASPPTSLLAPSTN----PLLESLKKMQTPPS---LPPCPESAGAAT 205 Query: 182 SGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQ 241 + T L P L S+ G +PS PP+ L A VP+ +P Sbjct: 206 TEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLLGLIPAPSMVPA-TDTKAPP 264 Query: 242 TLQPVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPL--SANYSSPLW 294 TLQ + P T A +P S L G ++ SP SP +A+ +SP++ Sbjct: 265 TLQ----AETTTKPQATSAPSPAP---KQSFLFGTQNTSPSSPAAPAASSASPMF 312 >gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f [Homo sapiens] Length = 1412 Score = 38.1 bits (87), Expect = 0.014 Identities = 85/373 (22%), Positives = 127/373 (34%), Gaps = 61/373 (16%) Query: 22 TEMKKVARQLGMAAAESDKDSG-FSDGSSECLSSAEQMESEDMLSALGWSREDRPRQNSK 80 T ++A + MA A S K+S SDG + E Q SK Sbjct: 949 TAHPRIAPKASMAGASSSKESSRISDGKKQ---------------------EGPATQVSK 987 Query: 81 TAKNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEVISAQPQLLFLHPPVPSPVSP 140 KN P P+ ++ Q +S +Q QPS V SA L P SP S Sbjct: 988 --KN--PASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTL-----PATSPQST 1038 Query: 141 CHTGEKKSDSRN-YLPILNSYTKIAPHPG-----KRGLSLGPEEKGTSGVQKKICTERLG 194 + + R LP + TK AP S G EE G G Sbjct: 1039 SVQAKGTNKLRKPKLPEVQQATK-APESSDDSEDSSDSSSGSEEDGE------------G 1085 Query: 195 PSLSSSEPTKAGAVPSSPSTPAPPSA-KLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAK 253 P + S T G PS T +A + +ED + SL++G L P +S Sbjct: 1086 PQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKA 1145 Query: 254 APSLTFASPASPVCASDSTLHGLESNSP------LSPLSANYSSPLWAAEHLCRSPDIFS 307 P L + S A+ G + P LSP + + R P + Sbjct: 1146 TPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGA 1205 Query: 308 EQRQSKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQVELDQLKEQTQLFIEATKSR 367 Q+ Q+ + LL E Q +V + L+++ + ++ TK Sbjct: 1206 GNPQASTLALQSNIT----QCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKES 1261 Query: 368 APQAWAKLQASLT 380 + + W + L+ Sbjct: 1262 SRKGWESRKRKLS 1274 Score = 34.3 bits (77), Expect = 0.20 Identities = 62/254 (24%), Positives = 94/254 (37%), Gaps = 30/254 (11%) Query: 6 PSRESPRRLSAKVGKGTEMKKVAR-QLGMAAAESDKDSGFSDGSSECLSSAEQMESEDML 64 P++ESPR+ +A G VA+ Q G +S S SD E + A+ + Sbjct: 300 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 359 Query: 65 SALGWSREDRPRQNSKTA--KNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEVIS 122 A ++ PR+ + A + P + + V K ++ S SS +S + + + ++ Sbjct: 360 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ---EEDSRSSSEESDSDREALAAMN 416 Query: 123 AQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTS 182 A P P S G L P PGK +GP T Sbjct: 417 AAQVKPLGKSPQVKPASTMGMGP-----------LGKGAGPVP-PGK----VGP---ATP 457 Query: 183 GVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVP-SLVAGGSPQ 241 Q E S S + G VP T P+ + + + LQ P S A G PQ Sbjct: 458 SAQVGKWEEDSESSSEESSDSSDGEVP----TAVAPAQEKSLGNILQAKPTSSPAKGPPQ 513 Query: 242 TLQPVSSSHVAKAP 255 PV+ A+ P Sbjct: 514 KAGPVAVQVKAEKP 527 >gi|154090979 hypothetical protein LOC57481 [Homo sapiens] Length = 1709 Score = 38.1 bits (87), Expect = 0.014 Identities = 61/277 (22%), Positives = 111/277 (40%), Gaps = 32/277 (11%) Query: 39 DKDSGFSDGSSECLSSA--EQMESEDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMK 96 D S + CLS A E ++E + + + + +++ P P + Sbjct: 824 DLSSSEEELDLRCLSQALEEPEDAEVFTESSSYVEKYNTSDDCSSSEEDLPLRHPAQALG 883 Query: 97 NVLVKQGSSSSQLQSWTVQPSF--EVISAQPQLLFLHPPVPS--PVSPCHTGEKKSDSRN 152 +Q SS+ + Q F ++ S P ++P V P S T K+SDS Sbjct: 884 KPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPTVQQQVPTSSVGTSIKQSDSVE 943 Query: 153 YLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSP 212 +P + + ++ +S P+ + V++ I + L P L +P V + Sbjct: 944 PIPPRHPFQPWVNPKVEQEVSSSPK---SMAVEESISMKPLPPKLLC-QPLMNPKVQQNM 999 Query: 213 STPAPPSAKLAEDSALQGVPS---LVAGGSPQTLQPVSSSHVAKAPSL---TFASPASPV 266 + + ED A++ V S L+ SPQ+L ++++ ++ T+ P P Sbjct: 1000 FSGS-------EDIAVERVISVEPLLPRYSPQSLTDPQIRQISESTAVEEGTYVEPLPPR 1052 Query: 267 CAS---------DSTLHGLESNSPLSPLSANYSSPLW 294 C S DS E +SP++P + Y+SP W Sbjct: 1053 CLSQPSERPKFLDSMSTSAEWSSPVAPTPSKYTSPPW 1089 >gi|15147240 brother of CDO [Homo sapiens] Length = 1114 Score = 38.1 bits (87), Expect = 0.014 Identities = 34/125 (27%), Positives = 48/125 (38%), Gaps = 14/125 (11%) Query: 151 RNYLPILNSYTKIAPHPGKRGLSLGPEEKGT-------------SGVQKKICTERLGPSL 197 RN +P+++S R LS+GPE++G + VQ + + P L Sbjct: 358 RNAVPLISSQRLRLSRRALRVLSMGPEDEGVYQCMAENEVGSAHAVVQLRTSRPSITPRL 417 Query: 198 SSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPSL 257 G P SPS P L AL P+ V SPQ A+AP + Sbjct: 418 WQDAELATGTPPVSPSKLGNPEQMLRGQPALPRPPTSVGPASPQCPGEKGQGAPAEAP-I 476 Query: 258 TFASP 262 +SP Sbjct: 477 ILSSP 481 >gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo sapiens] Length = 1450 Score = 37.7 bits (86), Expect = 0.018 Identities = 76/344 (22%), Positives = 119/344 (34%), Gaps = 35/344 (10%) Query: 49 SECLSSAEQMESEDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQGSSSSQ 108 S SS+ + E ED++ A R N T A P ++P M + SS Sbjct: 992 STARSSSSESEDEDVIPATQCLTPGI-RTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 1050 Query: 109 LQSWTVQPSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRN-YLPILNSYTKIAPHP 167 P+ +V SA L P SP S + + R LP + TK AP Sbjct: 1051 DGKKQEGPATQVDSAVGTL-----PATSPQSTSVQAKGTNKLRKPKLPEVQQATK-APES 1104 Query: 168 G-----KRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKL 222 S G EE G G Q LGP+ S +E + +A+ Sbjct: 1105 SDDSEDSSDSSSGSEEDG-EGPQGAKSAHTLGPTPSRTE-----------TLVEETAAES 1152 Query: 223 AEDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSP- 281 +ED + SL++G L P +S P L + S A+ G + P Sbjct: 1153 SEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQ 1212 Query: 282 -----LSPLSANYSSPLWAAEHLCRSPDIFSEQRQSKHRRFQNTLVVLHKSGLLEITLKT 336 LSP + + R P + Q+ Q+ + LL Sbjct: 1213 QAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT----QCLLGQPWPL 1268 Query: 337 KELIRQNQATQVELDQLKEQTQLFIEATKSRAPQAWAKLQASLT 380 E Q +V + L+++ + ++ TK + + W + L+ Sbjct: 1269 NEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS 1312 Score = 34.3 bits (77), Expect = 0.20 Identities = 62/254 (24%), Positives = 94/254 (37%), Gaps = 30/254 (11%) Query: 6 PSRESPRRLSAKVGKGTEMKKVAR-QLGMAAAESDKDSGFSDGSSECLSSAEQMESEDML 64 P++ESPR+ +A G VA+ Q G +S S SD E + A+ + Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436 Query: 65 SALGWSREDRPRQNSKTA--KNAFPTLSPMVVMKNVLVKQGSSSSQLQSWTVQPSFEVIS 122 A ++ PR+ + A + P + + V K ++ S SS +S + + + ++ Sbjct: 437 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ---EEDSRSSSEESDSDREALAAMN 493 Query: 123 AQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTS 182 A P P S G L P PGK +GP T Sbjct: 494 AAQVKPLGKSPQVKPASTMGMGP-----------LGKGAGPVP-PGK----VGP---ATP 534 Query: 183 GVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVP-SLVAGGSPQ 241 Q E S S + G VP T P+ + + + LQ P S A G PQ Sbjct: 535 SAQVGKWEEDSESSSEESSDSSDGEVP----TAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590 Query: 242 TLQPVSSSHVAKAP 255 PV+ A+ P Sbjct: 591 KAGPVAVQVKAEKP 604 >gi|216547801 SH2 domain containing 3C isoform e [Homo sapiens] Length = 700 Score = 37.7 bits (86), Expect = 0.018 Identities = 46/191 (24%), Positives = 77/191 (40%), Gaps = 24/191 (12%) Query: 95 MKNVLVKQGSSSSQLQSWTVQPSFEVISAQPQLLFLHPPVPSPVSPCHTGEKKSDSRNYL 154 + V+VK G S + +Q Q SF+ + P L+ H VS ++S + Y Sbjct: 107 INKVVVKAGESYTHIQYLFEQESFDHV---PALVRYHVGSRKAVS------EQSGAIIYC 157 Query: 155 PILNSYTKIAPHPGKRGLSLGPEE-------KGTSGVQKKICTERLGPSLSSSEPTKAGA 207 P+ ++ + GL G + G G K + + L++ + T++ Sbjct: 158 PVNRTFP-LRYLEASYGLGQGSSKPASPVSPSGPKGSHMKRRSVTMTDGLTADKVTRSDG 216 Query: 208 VPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQP-------VSSSHVAKAPSLTFA 260 P+S S P P + + ++ +P L + SP + P V+ H A A A Sbjct: 217 CPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATA 276 Query: 261 SPASPVCASDS 271 PASPV S Sbjct: 277 LPASPVARRSS 287 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.123 0.346 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,257,970 Number of Sequences: 37866 Number of extensions: 911408 Number of successful extensions: 5712 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 47 Number of HSP's successfully gapped in prelim test: 448 Number of HSP's that attempted gapping in prelim test: 4855 Number of HSP's gapped (non-prelim): 1139 length of query: 399 length of database: 18,247,518 effective HSP length: 104 effective length of query: 295 effective length of database: 14,309,454 effective search space: 4221288930 effective search space used: 4221288930 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.