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Search of human proteins with 31982933
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31982933 inhibitor of DNA binding 2 [Homo sapiens]
(134 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31982933 inhibitor of DNA binding 2 [Homo sapiens] 266 4e-72
gi|4504573 inhibitor of DNA binding 4, dominant negative helix-l... 95 2e-20
gi|31317299 inhibitor of DNA binding 1 isoform a [Homo sapiens] 94 3e-20
gi|31317297 inhibitor of DNA binding 1 isoform b [Homo sapiens] 89 8e-19
gi|156119621 inhibitor of DNA binding 3 [Homo sapiens] 84 3e-17
gi|55743094 achaete-scute complex homolog 1 [Homo sapiens] 39 0.001
gi|116517330 factor in the germline alpha [Homo sapiens] 39 0.002
gi|161484632 nescient helix loop helix 2 [Homo sapiens] 38 0.003
gi|5031945 nescient helix loop helix 2 [Homo sapiens] 38 0.003
gi|5031943 nescient helix loop helix 1 [Homo sapiens] 38 0.003
gi|38455396 neurogenin 1 [Homo sapiens] 37 0.004
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens] 37 0.006
gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens] 36 0.008
gi|68989258 neurogenin 3 [Homo sapiens] 35 0.018
gi|21553337 atonal homolog 7 [Homo sapiens] 35 0.018
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi... 34 0.031
gi|206597481 achaete-scute complex-like 4 [Homo sapiens] 34 0.040
gi|169213965 PREDICTED: similar to hCG1645909 [Homo sapiens] 33 0.069
gi|239751822 PREDICTED: similar to hCG1645909 [Homo sapiens] 33 0.069
gi|239746313 PREDICTED: similar to hCG1645909 [Homo sapiens] 33 0.069
gi|23097242 nephew of atonal 3 [Homo sapiens] 33 0.069
gi|31077092 neurogenin 2 [Homo sapiens] 33 0.069
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi... 33 0.089
gi|30039710 pancreas specific transcription factor, 1a [Homo sap... 33 0.089
gi|4758506 basic helix-loop-helix transcription factor HAND1 [Ho... 32 0.12
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H... 32 0.15
gi|4885075 atonal homolog 1 [Homo sapiens] 32 0.20
gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens] 31 0.26
gi|27475985 neurogenic differentiation 6 [Homo sapiens] 31 0.26
gi|148922889 scleraxis homolog B [Homo sapiens] 31 0.34
>gi|31982933 inhibitor of DNA binding 2 [Homo sapiens]
Length = 134
Score = 266 bits (680), Expect = 4e-72
Identities = 134/134 (100%), Positives = 134/134 (100%)
Query: 1 MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVS 60
MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVS
Sbjct: 1 MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVS 60
Query: 61 KMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEF 120
KMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEF
Sbjct: 61 KMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEF 120
Query: 121 PSELMSNDSKALCG 134
PSELMSNDSKALCG
Sbjct: 121 PSELMSNDSKALCG 134
>gi|4504573 inhibitor of DNA binding 4, dominant negative
helix-loop-helix protein [Homo sapiens]
Length = 161
Score = 94.7 bits (234), Expect = 2e-20
Identities = 64/146 (43%), Positives = 82/146 (56%), Gaps = 37/146 (25%)
Query: 1 MKAFSPVRSVRKNSLSD---------------HSLGISRS-------------KTPVDDP 32
MKA SPVR + + S HSLG S + + D+P
Sbjct: 1 MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAAAAAAAAAARCKAAEAAADEP 60
Query: 33 -MSLLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTIV----- 86
+ L +MNDCYS+L+ LVP+IP NKKVSK+EILQHVIDYILDLQ+AL++HP ++
Sbjct: 61 ALCLQCDMNDCYSRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALETHPALLRQPPP 120
Query: 87 -SLHHQRPGQNQAS--RTPLTTLNTD 109
+ H G A+ RTPLT LNTD
Sbjct: 121 PAPPHHPAGTCPAAPPRTPLTALNTD 146
>gi|31317299 inhibitor of DNA binding 1 isoform a [Homo sapiens]
Length = 155
Score = 94.0 bits (232), Expect = 3e-20
Identities = 51/99 (51%), Positives = 69/99 (69%), Gaps = 9/99 (9%)
Query: 35 LLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPG 94
LLY+MN CYS+LKELVP++PQN+KVSK+EILQHVIDYI DLQ+ L+S + + G
Sbjct: 65 LLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGT----PGG 120
Query: 95 QNQASRTPLTTLNTDISILSLQASEFPSELMSNDSKALC 133
+ R PL+TLN +IS L+ +A+ P+ D + LC
Sbjct: 121 RGLPVRAPLSTLNGEISALTAEAACVPA-----DDRILC 154
>gi|31317297 inhibitor of DNA binding 1 isoform b [Homo sapiens]
Length = 149
Score = 89.4 bits (220), Expect = 8e-19
Identities = 46/82 (56%), Positives = 61/82 (74%), Gaps = 4/82 (4%)
Query: 35 LLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPG 94
LLY+MN CYS+LKELVP++PQN+KVSK+EILQHVIDYI DLQ+ L+S + + G
Sbjct: 65 LLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGT----PGG 120
Query: 95 QNQASRTPLTTLNTDISILSLQ 116
+ R PL+TLN +IS L+ +
Sbjct: 121 RGLPVRAPLSTLNGEISALTAE 142
>gi|156119621 inhibitor of DNA binding 3 [Homo sapiens]
Length = 119
Score = 84.3 bits (207), Expect = 3e-17
Identities = 54/138 (39%), Positives = 77/138 (55%), Gaps = 25/138 (18%)
Query: 1 MKAFSPVRSVRKN--SLSDHSLGISRSK---TPVDDPMSLLYNMNDCYSKLKELVPSIPQ 55
MKA SPVR + LS+ SL I+R + ++P+SLL +MN CYS+L+ELVP +P+
Sbjct: 1 MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPR 60
Query: 56 NKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSL 115
++S++EILQ VIDYILDLQ+ L + P PG P+ T
Sbjct: 61 GTQLSQVEILQRVIDYILDLQVVL-AEPA--------PGPPDGPHLPIQT---------- 101
Query: 116 QASEFPSELMSNDSKALC 133
A P ++SND ++ C
Sbjct: 102 -AELTPELVISNDKRSFC 118
>gi|55743094 achaete-scute complex homolog 1 [Homo sapiens]
Length = 236
Score = 38.9 bits (89), Expect = 0.001
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 43 YSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTI 85
++ L+E VP+ NKK+SK+E L+ ++YI LQ LD H +
Sbjct: 138 FATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAV 180
>gi|116517330 factor in the germline alpha [Homo sapiens]
Length = 219
Score = 38.5 bits (88), Expect = 0.002
Identities = 18/43 (41%), Positives = 30/43 (69%)
Query: 38 NMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALD 80
N+N +++LK LVP +PQ++K SK++IL+ +YI L L+
Sbjct: 80 NLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLLE 122
>gi|161484632 nescient helix loop helix 2 [Homo sapiens]
Length = 135
Score = 37.7 bits (86), Expect = 0.003
Identities = 18/41 (43%), Positives = 30/41 (73%)
Query: 40 NDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALD 80
N +++L++L+P++P +KK+SK+EIL+ I YI L LD
Sbjct: 94 NLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLD 134
>gi|5031945 nescient helix loop helix 2 [Homo sapiens]
Length = 135
Score = 37.7 bits (86), Expect = 0.003
Identities = 18/41 (43%), Positives = 30/41 (73%)
Query: 40 NDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALD 80
N +++L++L+P++P +KK+SK+EIL+ I YI L LD
Sbjct: 94 NLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLD 134
>gi|5031943 nescient helix loop helix 1 [Homo sapiens]
Length = 133
Score = 37.7 bits (86), Expect = 0.003
Identities = 18/41 (43%), Positives = 30/41 (73%)
Query: 40 NDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALD 80
N +++L++L+P++P +KK+SK+EIL+ I YI L LD
Sbjct: 92 NLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLD 132
>gi|38455396 neurogenin 1 [Homo sapiens]
Length = 237
Score = 37.4 bits (85), Expect = 0.004
Identities = 18/55 (32%), Positives = 31/55 (56%)
Query: 18 HSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYI 72
HSL SR D + ++N+N L+ ++PS P + K++K+E L+ +YI
Sbjct: 87 HSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYI 141
>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
Length = 331
Score = 36.6 bits (83), Expect = 0.006
Identities = 15/35 (42%), Positives = 27/35 (77%)
Query: 38 NMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYI 72
N+N +++L++L+P+ P +KK+SK EIL+ + YI
Sbjct: 202 NVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYI 236
>gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]
Length = 108
Score = 36.2 bits (82), Expect = 0.008
Identities = 15/35 (42%), Positives = 26/35 (74%)
Query: 38 NMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYI 72
N+N ++KL++L+P+ P +KK+SK E L+ + YI
Sbjct: 17 NVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYI 51
>gi|68989258 neurogenin 3 [Homo sapiens]
Length = 214
Score = 35.0 bits (79), Expect = 0.018
Identities = 19/65 (29%), Positives = 35/65 (53%)
Query: 8 RSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVSKMEILQH 67
RS K+ L+ SR K D + ++N+N L+ ++P+ P + K++K+E L+
Sbjct: 68 RSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRF 127
Query: 68 VIDYI 72
+YI
Sbjct: 128 AHNYI 132
>gi|21553337 atonal homolog 7 [Homo sapiens]
Length = 152
Score = 35.0 bits (79), Expect = 0.018
Identities = 15/40 (37%), Positives = 25/40 (62%)
Query: 36 LYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDL 75
+ +N + +L+ +VP Q+KK+SK E LQ + YI+ L
Sbjct: 53 MQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMAL 92
>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
sapiens]
Length = 280
Score = 34.3 bits (77), Expect = 0.031
Identities = 13/35 (37%), Positives = 27/35 (77%)
Query: 38 NMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYI 72
N+N +++L++L+P+ P ++K+SK E+L+ + YI
Sbjct: 165 NVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYI 199
>gi|206597481 achaete-scute complex-like 4 [Homo sapiens]
Length = 173
Score = 33.9 bits (76), Expect = 0.040
Identities = 16/42 (38%), Positives = 29/42 (69%)
Query: 39 MNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALD 80
+N+ Y++L++ +P +K++SK+E L+ IDYI LQ L+
Sbjct: 89 VNEGYARLRDHLPRELADKRLSKVETLRAAIDYIKHLQELLE 130
>gi|169213965 PREDICTED: similar to hCG1645909 [Homo sapiens]
Length = 591
Score = 33.1 bits (74), Expect = 0.069
Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 5/51 (9%)
Query: 44 SKLKELVPSIP-----QNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLH 89
SKL+EL +P KK++K EIL HV+ YI LQ +D+ + H
Sbjct: 33 SKLQELALLLPIALKTGTKKLTKKEILVHVLQYIQYLQRNIDAAKALFKCH 83
>gi|239751822 PREDICTED: similar to hCG1645909 [Homo sapiens]
Length = 591
Score = 33.1 bits (74), Expect = 0.069
Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 5/51 (9%)
Query: 44 SKLKELVPSIP-----QNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLH 89
SKL+EL +P KK++K EIL HV+ YI LQ +D+ + H
Sbjct: 33 SKLQELALLLPIALKTGTKKLTKKEILVHVLQYIQYLQRNIDAAKALFKCH 83
>gi|239746313 PREDICTED: similar to hCG1645909 [Homo sapiens]
Length = 591
Score = 33.1 bits (74), Expect = 0.069
Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 5/51 (9%)
Query: 44 SKLKELVPSIP-----QNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLH 89
SKL+EL +P KK++K EIL HV+ YI LQ +D+ + H
Sbjct: 33 SKLQELALLLPIALKTGTKKLTKKEILVHVLQYIQYLQRNIDAAKALFKCH 83
>gi|23097242 nephew of atonal 3 [Homo sapiens]
Length = 166
Score = 33.1 bits (74), Expect = 0.069
Identities = 14/46 (30%), Positives = 29/46 (63%)
Query: 36 LYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDS 81
++N+N+ + +L+ VP+ K++S++E L+ I YI + L+S
Sbjct: 114 MFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLES 159
>gi|31077092 neurogenin 2 [Homo sapiens]
Length = 272
Score = 33.1 bits (74), Expect = 0.069
Identities = 12/37 (32%), Positives = 26/37 (70%)
Query: 36 LYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYI 72
++N+N L+E++P+ P++ K++K+E L+ +YI
Sbjct: 125 MHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYI 161
>gi|29126247 basic helix-loop-helix family, member a15 [Homo
sapiens]
Length = 189
Score = 32.7 bits (73), Expect = 0.089
Identities = 13/40 (32%), Positives = 26/40 (65%)
Query: 36 LYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDL 75
++ +N+ + L+E++P + +KK+SK+E L +YI L
Sbjct: 88 MHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSL 127
>gi|30039710 pancreas specific transcription factor, 1a [Homo
sapiens]
Length = 328
Score = 32.7 bits (73), Expect = 0.089
Identities = 12/37 (32%), Positives = 25/37 (67%)
Query: 36 LYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYI 72
+ ++ND + L+ +P++P K++SK++ L+ I YI
Sbjct: 176 MQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYI 212
>gi|4758506 basic helix-loop-helix transcription factor HAND1 [Homo
sapiens]
Length = 215
Score = 32.3 bits (72), Expect = 0.12
Identities = 13/42 (30%), Positives = 27/42 (64%)
Query: 38 NMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIAL 79
++N +++L+E +P++P + K+SK++ L+ YI L L
Sbjct: 109 SINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVL 150
>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
sapiens]
Length = 217
Score = 32.0 bits (71), Expect = 0.15
Identities = 11/35 (31%), Positives = 25/35 (71%)
Query: 38 NMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYI 72
++N +++L+E +P++P + K+SK++ L+ YI
Sbjct: 114 SINSAFAELRECIPNVPADTKLSKIKTLRLATSYI 148
>gi|4885075 atonal homolog 1 [Homo sapiens]
Length = 354
Score = 31.6 bits (70), Expect = 0.20
Identities = 13/37 (35%), Positives = 23/37 (62%)
Query: 36 LYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYI 72
++ +N + +L+ ++PS +KK+SK E LQ YI
Sbjct: 172 MHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYI 208
>gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]
Length = 193
Score = 31.2 bits (69), Expect = 0.26
Identities = 15/43 (34%), Positives = 25/43 (58%)
Query: 43 YSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTI 85
+ L++ VP +KK+SK+E L+ ++YI LQ L H +
Sbjct: 70 FQALRQHVPHGGASKKLSKVETLRSAVEYIRALQRLLAEHDAV 112
>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
Length = 337
Score = 31.2 bits (69), Expect = 0.26
Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 7/87 (8%)
Query: 36 LYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQ--IALDSHPTIVSLHHQRP 93
++ +ND L+++VP + +K+SK+E L+ +YI L + + P +++
Sbjct: 107 MHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTF----- 161
Query: 94 GQNQASRTPLTTLNTDISILSLQASEF 120
QN T N L L A F
Sbjct: 162 VQNLCKGLSQPTTNLVAGCLQLNARSF 188
>gi|148922889 scleraxis homolog B [Homo sapiens]
Length = 201
Score = 30.8 bits (68), Expect = 0.34
Identities = 13/38 (34%), Positives = 25/38 (65%)
Query: 38 NMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDL 75
++N ++ L+ L+P+ P ++K+SK+E L+ YI L
Sbjct: 90 SVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHL 127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,627,378
Number of Sequences: 37866
Number of extensions: 174669
Number of successful extensions: 605
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 548
Number of HSP's gapped (non-prelim): 68
length of query: 134
length of database: 18,247,518
effective HSP length: 91
effective length of query: 43
effective length of database: 14,801,712
effective search space: 636473616
effective search space used: 636473616
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.