BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31742516 frataxin isoform 2 preproprotein [Homo sapiens] (196 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31742516 frataxin isoform 2 preproprotein [Homo sapiens] 402 e-113 gi|239787198 frataxin isoform 3 preproprotein [Homo sapiens] 327 3e-90 gi|31077081 frataxin isoform 1 preproprotein [Homo sapiens] 325 1e-89 gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens] 32 0.35 gi|169164783 PREDICTED: hypothetical protein [Homo sapiens] 31 0.77 gi|169163482 PREDICTED: hypothetical protein [Homo sapiens] 31 0.77 gi|148922920 DENN/MADD domain containing 4B [Homo sapiens] 30 1.0 gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens] 30 1.3 gi|47458820 signal transducer and activator of transcription 3 i... 30 1.3 gi|21618338 signal transducer and activator of transcription 3 i... 30 1.3 gi|21618340 signal transducer and activator of transcription 3 i... 30 1.3 gi|239751624 PREDICTED: hypothetical protein XP_002347938 [Homo ... 29 2.2 gi|239746135 PREDICTED: hypothetical protein XP_002344205 [Homo ... 29 2.2 gi|89941479 hypothetical protein LOC148137 [Homo sapiens] 29 2.2 gi|34486092 adenylate cyclase 5 [Homo sapiens] 29 2.9 gi|222446609 rai-like protein [Homo sapiens] 28 3.8 gi|239757070 PREDICTED: hypothetical protein [Homo sapiens] 28 3.8 gi|239751580 PREDICTED: hypothetical protein [Homo sapiens] 28 3.8 gi|239746092 PREDICTED: hypothetical protein XP_002343656 [Homo ... 28 3.8 gi|169168202 PREDICTED: hypothetical protein [Homo sapiens] 28 5.0 gi|169167967 PREDICTED: hypothetical protein [Homo sapiens] 28 5.0 gi|169167681 PREDICTED: hypothetical protein [Homo sapiens] 28 5.0 gi|4557485 ceruloplasmin precursor [Homo sapiens] 28 6.5 gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 27 8.5 >gi|31742516 frataxin isoform 2 preproprotein [Homo sapiens] Length = 196 Score = 402 bits (1034), Expect = e-113 Identities = 196/196 (100%), Positives = 196/196 (100%) Query: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR Sbjct: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60 Query: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF Sbjct: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120 Query: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPT 180 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPT Sbjct: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPT 180 Query: 181 TACPSMSCWPQSSLKP 196 TACPSMSCWPQSSLKP Sbjct: 181 TACPSMSCWPQSSLKP 196 >gi|239787198 frataxin isoform 3 preproprotein [Homo sapiens] Length = 171 Score = 327 bits (839), Expect = 3e-90 Identities = 161/161 (100%), Positives = 161/161 (100%) Query: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR Sbjct: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60 Query: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF Sbjct: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120 Query: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSR 161 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSR Sbjct: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSR 161 >gi|31077081 frataxin isoform 1 preproprotein [Homo sapiens] Length = 210 Score = 325 bits (834), Expect = 1e-89 Identities = 160/160 (100%), Positives = 160/160 (100%) Query: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR Sbjct: 1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR 60 Query: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF Sbjct: 61 GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF 120 Query: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPS 160 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPS Sbjct: 121 EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPS 160 >gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens] Length = 1684 Score = 32.0 bits (71), Expect = 0.35 Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 13/100 (13%) Query: 29 RPAELAPLCGRRGLRTDIDATCTPRRASSNQRGLNQIWNVKKQSVYLMNLRKSGTLGHPG 88 +P PL R +I++T + ++SS+ + W K++S+ + ++ H G Sbjct: 543 KPPRTLPLHSRDW---EIESTSSESKSSSSSK-YRPTWRPKRESLNIDSIFSKDKRKHCG 598 Query: 89 SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFG 128 Y +L+ + DS EF D KP YD+ FG Sbjct: 599 ------YTQLSPFSEDSAKEFIPDEPSKP---PSYDIKFG 629 >gi|169164783 PREDICTED: hypothetical protein [Homo sapiens] Length = 396 Score = 30.8 bits (68), Expect = 0.77 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 12/88 (13%) Query: 5 GRRAVAGLLASPSPAQAQTLTRVPRPAELAPL--CGRRGLRTDIDATCTPRRASSNQRGL 62 G+R GL S PA A++ R PRP L P G LR T R SS+ G+ Sbjct: 19 GQRRAPGLPRSSGPAWAESRARPPRPRGLEPRHPPGSPALRP------TDRTCSSSSAGV 72 Query: 63 -NQIWNVKKQSVYL---MNLRKSGTLGH 86 + + SV L + L + TLGH Sbjct: 73 GGGVGGAQPGSVPLGQHLALERGRTLGH 100 >gi|169163482 PREDICTED: hypothetical protein [Homo sapiens] Length = 396 Score = 30.8 bits (68), Expect = 0.77 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 12/88 (13%) Query: 5 GRRAVAGLLASPSPAQAQTLTRVPRPAELAPL--CGRRGLRTDIDATCTPRRASSNQRGL 62 G+R GL S PA A++ R PRP L P G LR T R SS+ G+ Sbjct: 19 GQRRAPGLPRSSGPAWAESRARPPRPRGLEPRHPPGSPALRP------TDRTCSSSSAGV 72 Query: 63 -NQIWNVKKQSVYL---MNLRKSGTLGH 86 + + SV L + L + TLGH Sbjct: 73 GGGVGGAQPGSVPLGQHLALERGRTLGH 100 >gi|148922920 DENN/MADD domain containing 4B [Homo sapiens] Length = 1496 Score = 30.4 bits (67), Expect = 1.0 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 8/89 (8%) Query: 17 SPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRR-----ASSNQRGLNQIWNVKKQ 71 +P++ +R+P P EL P R+ +D+ PR AS + L W++ + Sbjct: 1066 TPSRHSPASRIP-PPELPPDLPPPARRSPMDSLLHPRERPGSTASESSASLGSEWDLSES 1124 Query: 72 SVYLMNLRKSG--TLGHPGSLDETTYERL 98 S+ ++LR+S PGS + E L Sbjct: 1125 SLSNLSLRRSSERLSDTPGSFQSPSLEIL 1153 >gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens] Length = 380 Score = 30.0 bits (66), Expect = 1.3 Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 1/43 (2%) Query: 4 LGRRAVAGL-LASPSPAQAQTLTRVPRPAELAPLCGRRGLRTD 45 L R+A G L SPSP P P P CGR + TD Sbjct: 141 LSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARVHTD 183 >gi|47458820 signal transducer and activator of transcription 3 isoform 3 [Homo sapiens] Length = 722 Score = 30.0 bits (66), Expect = 1.3 Identities = 18/75 (24%), Positives = 33/75 (44%) Query: 79 RKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGG 138 ++ G HP + T +++ E+ L + + +DL K E+ F T+K G Sbjct: 124 QQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQG 183 Query: 139 DLGTYVINKQTPNKQ 153 D+ N Q+ +Q Sbjct: 184 DMQDLNGNNQSVTRQ 198 >gi|21618338 signal transducer and activator of transcription 3 isoform 2 [Homo sapiens] Length = 769 Score = 30.0 bits (66), Expect = 1.3 Identities = 18/75 (24%), Positives = 33/75 (44%) Query: 79 RKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGG 138 ++ G HP + T +++ E+ L + + +DL K E+ F T+K G Sbjct: 124 QQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQG 183 Query: 139 DLGTYVINKQTPNKQ 153 D+ N Q+ +Q Sbjct: 184 DMQDLNGNNQSVTRQ 198 >gi|21618340 signal transducer and activator of transcription 3 isoform 1 [Homo sapiens] Length = 770 Score = 30.0 bits (66), Expect = 1.3 Identities = 18/75 (24%), Positives = 33/75 (44%) Query: 79 RKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGG 138 ++ G HP + T +++ E+ L + + +DL K E+ F T+K G Sbjct: 124 QQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQG 183 Query: 139 DLGTYVINKQTPNKQ 153 D+ N Q+ +Q Sbjct: 184 DMQDLNGNNQSVTRQ 198 >gi|239751624 PREDICTED: hypothetical protein XP_002347938 [Homo sapiens] Length = 244 Score = 29.3 bits (64), Expect = 2.2 Identities = 14/27 (51%), Positives = 17/27 (62%) Query: 4 LGRRAVAGLLASPSPAQAQTLTRVPRP 30 +GRRA AGL A P P QA L + +P Sbjct: 85 VGRRAAAGLRAHPLPPQAPPLAQSSQP 111 >gi|239746135 PREDICTED: hypothetical protein XP_002344205 [Homo sapiens] Length = 244 Score = 29.3 bits (64), Expect = 2.2 Identities = 14/27 (51%), Positives = 17/27 (62%) Query: 4 LGRRAVAGLLASPSPAQAQTLTRVPRP 30 +GRRA AGL A P P QA L + +P Sbjct: 85 VGRRAAAGLRAHPLPPQAPPLAQSSQP 111 >gi|89941479 hypothetical protein LOC148137 [Homo sapiens] Length = 425 Score = 29.3 bits (64), Expect = 2.2 Identities = 16/24 (66%), Positives = 17/24 (70%), Gaps = 1/24 (4%) Query: 14 ASPSPAQAQTLTRVPRPA-ELAPL 36 ASP+PAQAQT T P PA APL Sbjct: 257 ASPAPAQAQTPTPAPAPASSQAPL 280 >gi|34486092 adenylate cyclase 5 [Homo sapiens] Length = 1261 Score = 28.9 bits (63), Expect = 2.9 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 15/87 (17%) Query: 78 LRKSGTLGHP----GSLDETTYERLAEETLDSLAEFFEDLADK-----PYTFEDYDVSFG 128 L K T+G L+++TY+++ + + +LA+F L D+ ++F ++ + G Sbjct: 1119 LEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIG 1178 Query: 129 SGVLTVKLGGDLGTYVINKQTPNKQIW 155 + V G VI + P IW Sbjct: 1179 LNIGPVVAG------VIGARKPQYDIW 1199 >gi|222446609 rai-like protein [Homo sapiens] Length = 630 Score = 28.5 bits (62), Expect = 3.8 Identities = 12/27 (44%), Positives = 14/27 (51%) Query: 82 GTLGHPGSLDETTYERLAEETLDSLAE 108 G GHPG L Y R E++ SL E Sbjct: 17 GLFGHPGMLHRAKYSRFRNESITSLDE 43 >gi|239757070 PREDICTED: hypothetical protein [Homo sapiens] Length = 195 Score = 28.5 bits (62), Expect = 3.8 Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 7/57 (12%) Query: 9 VAGLLASPSPAQAQTLTRVPRPAELAP----LCGRRGLRTDIDATCTPRRASSNQRG 61 VAG L P P R P+P P LC GLRT DA+ R A + G Sbjct: 137 VAGCLPLPRPRDG---ARSPQPLPWKPGLPSLCVASGLRTAPDASAPGRAAKTRSSG 190 >gi|239751580 PREDICTED: hypothetical protein [Homo sapiens] Length = 195 Score = 28.5 bits (62), Expect = 3.8 Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 7/57 (12%) Query: 9 VAGLLASPSPAQAQTLTRVPRPAELAP----LCGRRGLRTDIDATCTPRRASSNQRG 61 VAG L P P R P+P P LC GLRT DA+ R A + G Sbjct: 137 VAGCLPLPRPRDG---ARSPQPLPWKPGLPSLCVASGLRTAPDASAPGRAAKTRSSG 190 >gi|239746092 PREDICTED: hypothetical protein XP_002343656 [Homo sapiens] Length = 195 Score = 28.5 bits (62), Expect = 3.8 Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 7/57 (12%) Query: 9 VAGLLASPSPAQAQTLTRVPRPAELAP----LCGRRGLRTDIDATCTPRRASSNQRG 61 VAG L P P R P+P P LC GLRT DA+ R A + G Sbjct: 137 VAGCLPLPRPRDG---ARSPQPLPWKPGLPSLCVASGLRTAPDASAPGRAAKTRSSG 190 >gi|169168202 PREDICTED: hypothetical protein [Homo sapiens] Length = 460 Score = 28.1 bits (61), Expect = 5.0 Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 11/67 (16%) Query: 3 TLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQRGL 62 TL R+ LL SP P R P P GLR D D P R +QR + Sbjct: 340 TLAFRSRLPLLRSPGPEGTSDAARAPAP----------GLR-DRDLRAAPPRPRPSQRPV 388 Query: 63 NQIWNVK 69 + ++ VK Sbjct: 389 SGLFKVK 395 >gi|169167967 PREDICTED: hypothetical protein [Homo sapiens] Length = 460 Score = 28.1 bits (61), Expect = 5.0 Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 11/67 (16%) Query: 3 TLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQRGL 62 TL R+ LL SP P R P P GLR D D P R +QR + Sbjct: 340 TLAFRSRLPLLRSPGPEGTSDAARAPAP----------GLR-DRDLRAAPPRPRPSQRPV 388 Query: 63 NQIWNVK 69 + ++ VK Sbjct: 389 SGLFKVK 395 >gi|169167681 PREDICTED: hypothetical protein [Homo sapiens] Length = 460 Score = 28.1 bits (61), Expect = 5.0 Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 11/67 (16%) Query: 3 TLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQRGL 62 TL R+ LL SP P R P P GLR D D P R +QR + Sbjct: 340 TLAFRSRLPLLRSPGPEGTSDAARAPAP----------GLR-DRDLRAAPPRPRPSQRPV 388 Query: 63 NQIWNVK 69 + ++ VK Sbjct: 389 SGLFKVK 395 >gi|4557485 ceruloplasmin precursor [Homo sapiens] Length = 1065 Score = 27.7 bits (60), Expect = 6.5 Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 15/77 (19%) Query: 59 QRGLNQIWNVKKQSVYLM--------NLRKSGTLGHPGSLDETTYERLAEETLDSLAEFF 110 Q G ++I + K+++YL + K LG G + + ET D + Sbjct: 57 QNGPDRIGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPI-------IKAETGDKVYVHL 109 Query: 111 EDLADKPYTFEDYDVSF 127 ++LA +PYTF + +++ Sbjct: 110 KNLASRPYTFHSHGITY 126 Score = 27.7 bits (60), Expect = 6.5 Identities = 13/41 (31%), Positives = 22/41 (53%) Query: 104 DSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYV 144 D + F+++A +PY+ + V S +T L G+ TYV Sbjct: 818 DKVKIIFKNMATRPYSIHAHGVQTESSTVTPTLPGETLTYV 858 >gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] Length = 1544 Score = 27.3 bits (59), Expect = 8.5 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 6/113 (5%) Query: 12 LLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQRGL-NQIW-NVK 69 LLA PSPAQ + RP+ C RG R I++ + + GL ++ W VK Sbjct: 1370 LLAKPSPAQQTDRSSPVRPSSEKNDC-CRGKRDGINSLERKLKRRLEREGLSSERWERVK 1428 Query: 70 KQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFED 122 K +K L HP ++ ER L AE +D Y+ ++ Sbjct: 1429 KMRT---PKKKKIKLSHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQE 1478 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,846,195 Number of Sequences: 37866 Number of extensions: 346484 Number of successful extensions: 982 Number of sequences better than 10.0: 24 Number of HSP's better than 10.0 without gapping: 14 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 964 Number of HSP's gapped (non-prelim): 28 length of query: 196 length of database: 18,247,518 effective HSP length: 97 effective length of query: 99 effective length of database: 14,574,516 effective search space: 1442877084 effective search space used: 1442877084 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.