Guide to the Human Genome
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Name: STAT3 Sequence: fasta or formatted (769aa) NCBI GI: 21618338
Description:

signal transducer and activator of transcription 3 isoform 2

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [770aa] signal transducer and activator of transcription 3 isoform 1
alt prot [722aa] signal transducer and activator of transcription 3 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.7         44           2
 C cysteine            1.8         14           1
 D aspartate           4.2         32           2
 E glutamate           7.7         59           2
 F phenylalanine       3.9         30           2
 G glycine             5.1         39           2
 H histidine           1.7         13           1
 I isoleucine          5.3         41           2
 K lysine              6.1         47           2
 L leucine            10.7         82           2
 M methionine          3.5         27           1
 N asparagine          4.9         38           2
 P proline             4.4         34           2
 Q glutamine           7.8         60           2
 R arginine            4.6         35           2
 S serine              6.5         50           2
 T threonine           6.1         47           2
 V valine              5.3         41           3
 W tryptophan          2.0         15           1
 Y tyrosine            2.7         21           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   signal transducer and activator of transcription 3 i... 
STAT3                 0.997   signal transducer and activator of transcription 3 i...
STAT3                 0.924   signal transducer and activator of transcription 3 i...
STAT1                 0.494   signal transducer and activator of transcription 1 is...
STAT1                 0.490   signal transducer and activator of transcription 1 i...
STAT4                 0.439   signal transducer and activator of transcription 4 [H...
STAT2                 0.306   signal transducer and activator of transcription 2 [H...
STAT5B                0.190   signal transducer and activator of transcription 5B ...
STAT5A                0.188   signal transducer and activator of transcription 5A ...
STAT6                 0.109   signal transducer and activator of transcription 6 [...
NUMA1                 0.013   nuclear mitotic apparatus protein 1 
TPR                   0.013   nuclear pore complex-associated protein TPR 
MYH10                 0.012   myosin, heavy polypeptide 10, non-muscle 
CENPE                 0.011   centromere protein E 
MYH9                  0.011   myosin, heavy polypeptide 9, non-muscle 
EEA1                  0.010   early endosome antigen 1, 162kD 
PPFIBP1               0.010   PTPRF interacting protein binding protein 1 isoform ...
MACF1                 0.009   microfilament and actin filament cross-linker protei...
MAP1A                 0.009   microtubule-associated protein 1A 
CROCC                 0.009   ciliary rootlet coiled-coil 
GOLGA2                0.009   Golgi autoantigen, golgin subfamily a, 2 
WDR87                 0.009   NYD-SP11 protein 
AKAP9                 0.009   A-kinase anchor protein 9 isoform 3 
RPGRIP1               0.009   retinitis pigmentosa GTPase regulator interacting p...
KIF20B                0.009   M-phase phosphoprotein 1 
PHLDB3                0.009   pleckstrin homology-like domain, family B, member 3...
CCDC30                0.009   coiled-coil domain containing 30 
TNIP1                 0.009   TNFAIP3 interacting protein 1 
MACF1                 0.009   microfilament and actin filament cross-linker protei...
MYH11                 0.009   smooth muscle myosin heavy chain 11 isoform SM1A [Ho...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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