Guide to the Human Genome
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Name: FXN Sequence: fasta or formatted (196aa) NCBI GI: 31742516
Description:

frataxin isoform 2 preproprotein

Referenced in:

Heme
Iron, Copper, and Arsenic Metabolism

Other entries for this name:
alt prot [171aa] frataxin isoform 3 preproprotein
alt prot [210aa] frataxin isoform 1 preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6         13           1
 C cysteine            2.6          5           1
 D aspartate           5.1         10           1
 E glutamate           4.1          8           2
 F phenylalanine       2.0          4           2
 G glycine             8.2         16           2
 H histidine           0.5          1           1
 I isoleucine          2.0          4           1
 K lysine              4.6          9           2
 L leucine            11.7         23           2
 M methionine          2.0          4           1
 N asparagine          3.1          6           1
 P proline             7.1         14           1
 Q glutamine           4.1          8           1
 R arginine            6.6         13           2
 S serine              9.2         18           2
 T threonine           9.7         19           2
 V valine              5.6         11           2
 W tryptophan          2.0          4           1
 Y tyrosine            3.1          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   frataxin isoform 2 preproprotein 
FXN                   0.801   frataxin isoform 3 preproprotein 
FXN                   0.796   frataxin isoform 1 preproprotein 
USP54                 0.019   ubiquitin specific peptidase 54 
LOC100130897          0.016   PREDICTED: hypothetical protein 
LOC100130897          0.016   PREDICTED: hypothetical protein 
DENND4B               0.013   DENN/MADD domain containing 4B 
SASH3                 0.013   SAM and SH3 domain containing 3 
STAT3                 0.013   signal transducer and activator of transcription 3 i...
STAT3                 0.013   signal transducer and activator of transcription 3 i...
STAT3                 0.013   signal transducer and activator of transcription 3 i...
LOC100290893          0.011   PREDICTED: hypothetical protein XP_002347938 
LOC100288361          0.011   PREDICTED: hypothetical protein XP_002344205 
C19orf55              0.011   hypothetical protein LOC148137 
ADCY5                 0.011   adenylate cyclase 5 
SHC4                  0.008   rai-like protein 
LOC100293935          0.008   PREDICTED: hypothetical protein 
LOC100287289          0.008   PREDICTED: hypothetical protein 
LOC100287289          0.008   PREDICTED: hypothetical protein XP_002343656 
LOC100130128          0.008   PREDICTED: hypothetical protein 
LOC100130128          0.008   PREDICTED: hypothetical protein 
LOC100130128          0.008   PREDICTED: hypothetical protein 
CP                    0.008   ceruloplasmin precursor 
KDM5B                 0.005   jumonji, AT rich interactive domain 1B 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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