Search of human proteins with 31652244

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
         (1960 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]         4003   0.0  
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]         3947   0.0  
gi|40807477 retinoic acid induced 1 [Homo sapiens]                    249   2e-65
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     91   1e-17
gi|57864582 hornerin [Homo sapiens]                                    87   2e-16
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     86   3e-16
gi|60097902 filaggrin [Homo sapiens]                                   84   1e-15
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    82   5e-15
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    81   1e-14
gi|62122917 filaggrin family member 2 [Homo sapiens]                   79   3e-14
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    76   3e-13
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    76   3e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    68   8e-11
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       65   7e-10
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       65   9e-10
gi|150170670 piccolo isoform 2 [Homo sapiens]                          64   2e-09
gi|150378539 piccolo isoform 1 [Homo sapiens]                          64   2e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        63   2e-09
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    60   2e-08
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    59   6e-08
gi|93141033 PAX interacting protein 1 [Homo sapiens]                   59   6e-08
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]       59   6e-08
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       59   6e-08
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       59   6e-08
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        59   6e-08
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              59   6e-08
gi|33286444 mastermind-like 2 [Homo sapiens]                           57   1e-07
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ...    57   2e-07
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s...    56   3e-07
gi|30795231 brain abundant, membrane attached signal protein 1 [...    56   3e-07

>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
          Length = 1960

 Score = 4003 bits (10381), Expect = 0.0
 Identities = 1960/1960 (100%), Positives = 1960/1960 (100%)

Query: 1    MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 60
            MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR
Sbjct: 1    MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 60

Query: 61   GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 120
            GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP
Sbjct: 61   GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 120

Query: 121  PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV 180
            PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV
Sbjct: 121  PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV 180

Query: 181  QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS 240
            QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS
Sbjct: 181  QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS 240

Query: 241  SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF 300
            SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF
Sbjct: 241  SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF 300

Query: 301  EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF 360
            EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF
Sbjct: 301  EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF 360

Query: 361  HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP 420
            HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP
Sbjct: 361  HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP 420

Query: 421  TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT 480
            TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT
Sbjct: 421  TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT 480

Query: 481  PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540
            PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ
Sbjct: 481  PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540

Query: 541  STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600
            STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN
Sbjct: 541  STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600

Query: 601  EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660
            EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG
Sbjct: 601  EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660

Query: 661  GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN 720
            GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN
Sbjct: 661  GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN 720

Query: 721  VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG 780
            VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG
Sbjct: 721  VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG 780

Query: 781  SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP 840
            SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP
Sbjct: 781  SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP 840

Query: 841  IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL 900
            IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL
Sbjct: 841  IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL 900

Query: 901  NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES 960
            NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES
Sbjct: 901  NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES 960

Query: 961  YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP 1020
            YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP
Sbjct: 961  YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP 1020

Query: 1021 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN 1080
            GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN
Sbjct: 1021 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN 1080

Query: 1081 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK 1140
            SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK
Sbjct: 1081 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK 1140

Query: 1141 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1200
            DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS
Sbjct: 1141 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1200

Query: 1201 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF 1260
            SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF
Sbjct: 1201 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF 1260

Query: 1261 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL 1320
            ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL
Sbjct: 1261 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL 1320

Query: 1321 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV 1380
            PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV
Sbjct: 1321 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV 1380

Query: 1381 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS 1440
            TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS
Sbjct: 1381 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS 1440

Query: 1441 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV 1500
            VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV
Sbjct: 1441 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV 1500

Query: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560
            GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP
Sbjct: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560

Query: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620
            PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP
Sbjct: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620

Query: 1621 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK 1680
            LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK
Sbjct: 1621 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK 1680

Query: 1681 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK 1740
            ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK
Sbjct: 1681 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK 1740

Query: 1741 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR 1800
            RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR
Sbjct: 1741 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR 1800

Query: 1801 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL 1860
            SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL
Sbjct: 1801 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL 1860

Query: 1861 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL 1920
            WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL
Sbjct: 1861 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL 1920

Query: 1921 HEENFSVRCPKHKPPLPCPLPPLQNKTAKGSLSTEQSERG 1960
            HEENFSVRCPKHKPPLPCPLPPLQNKTAKGSLSTEQSERG
Sbjct: 1921 HEENFSVRCPKHKPPLPCPLPPLQNKTAKGSLSTEQSERG 1960


>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
          Length = 1938

 Score = 3947 bits (10235), Expect = 0.0
 Identities = 1933/1933 (100%), Positives = 1933/1933 (100%)

Query: 1    MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 60
            MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR
Sbjct: 1    MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 60

Query: 61   GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 120
            GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP
Sbjct: 61   GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 120

Query: 121  PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV 180
            PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV
Sbjct: 121  PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV 180

Query: 181  QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS 240
            QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS
Sbjct: 181  QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS 240

Query: 241  SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF 300
            SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF
Sbjct: 241  SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF 300

Query: 301  EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF 360
            EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF
Sbjct: 301  EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF 360

Query: 361  HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP 420
            HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP
Sbjct: 361  HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP 420

Query: 421  TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT 480
            TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT
Sbjct: 421  TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT 480

Query: 481  PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540
            PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ
Sbjct: 481  PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540

Query: 541  STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600
            STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN
Sbjct: 541  STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600

Query: 601  EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660
            EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG
Sbjct: 601  EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660

Query: 661  GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN 720
            GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN
Sbjct: 661  GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN 720

Query: 721  VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG 780
            VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG
Sbjct: 721  VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG 780

Query: 781  SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP 840
            SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP
Sbjct: 781  SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP 840

Query: 841  IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL 900
            IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL
Sbjct: 841  IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL 900

Query: 901  NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES 960
            NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES
Sbjct: 901  NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES 960

Query: 961  YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP 1020
            YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP
Sbjct: 961  YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP 1020

Query: 1021 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN 1080
            GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN
Sbjct: 1021 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN 1080

Query: 1081 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK 1140
            SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK
Sbjct: 1081 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK 1140

Query: 1141 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1200
            DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS
Sbjct: 1141 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1200

Query: 1201 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF 1260
            SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF
Sbjct: 1201 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF 1260

Query: 1261 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL 1320
            ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL
Sbjct: 1261 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL 1320

Query: 1321 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV 1380
            PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV
Sbjct: 1321 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV 1380

Query: 1381 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS 1440
            TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS
Sbjct: 1381 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS 1440

Query: 1441 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV 1500
            VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV
Sbjct: 1441 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV 1500

Query: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560
            GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP
Sbjct: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560

Query: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620
            PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP
Sbjct: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620

Query: 1621 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK 1680
            LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK
Sbjct: 1621 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK 1680

Query: 1681 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK 1740
            ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK
Sbjct: 1681 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK 1740

Query: 1741 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR 1800
            RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR
Sbjct: 1741 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR 1800

Query: 1801 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL 1860
            SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL
Sbjct: 1801 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL 1860

Query: 1861 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL 1920
            WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL
Sbjct: 1861 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL 1920

Query: 1921 HEENFSVRCPKHK 1933
            HEENFSVRCPKHK
Sbjct: 1921 HEENFSVRCPKHK 1933


>gi|40807477 retinoic acid induced 1 [Homo sapiens]
          Length = 1906

 Score =  249 bits (636), Expect = 2e-65
 Identities = 226/801 (28%), Positives = 351/801 (43%), Gaps = 114/801 (14%)

Query: 1192 SRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLP--GQEDHSSQN 1249
            S++  P++   P   +++K     H      ++ + Q     S   R+P  G     S  
Sbjct: 1158 SKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDR 1217

Query: 1250 PLIMRRRVRSFISPIPSKRQSQDVKNSSTEDK------GRLLHSSKEGADKAFNSYAHLS 1303
            PL   +R  +F++P+P+K+++  +++ S+         G       EG+   F   +   
Sbjct: 1218 PLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERPEGSPTLFKRMSSPK 1277

Query: 1304 HSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTSPA------KTKILPPRKGRGLKLEAIVQ 1357
             ++  K     + +  LP P++ +   + L S A      KTK+LPPRKGRGLKLEAIVQ
Sbjct: 1278 KAKPTKG--NGEPATKLPPPETPDA-CLKLASRAAFQGAMKTKVLPPRKGRGLKLEAIVQ 1334

Query: 1358 KITSPNIRRSASSNSAEAGGDTVT-----LDDILSLKSGPPEGGSVAVQDADIEKRKGEV 1412
            KITSP++++ A      + G+ ++      D  L    G P G    + +    ++    
Sbjct: 1335 KITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEGLVNVGTGQKLPTS 1394

Query: 1413 ASDLV--SPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQ 1470
             +D +  +P N+ L       +     + S  D  KTE  A T     +P G   +  + 
Sbjct: 1395 GADPLCRNPTNRSLK-----GKLMNSKKLSSTDCFKTE--AFTSPEALQPGG---TALAP 1444

Query: 1471 KPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPP 1530
            K  S +GR         PL       + P  +L P       ++ + T   S    G   
Sbjct: 1445 KKRSRKGRAGAHGLSKGPL--EKRPYLGPALLLTP------RDRASGTQGASEDNSGGGG 1496

Query: 1531 KGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQI----PEGSADGEPKPKKQRQRRER 1586
            K      K K   +G  +      QPP   P  PQ       G  +     K++R  R R
Sbjct: 1497 K------KPKMEELGLAS------QPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGR 1544

Query: 1587 RK-----PGAQPRKRKTKQAVPIVEPQEPEIKLKYATQ-PLDKTDAKNKSFYPYIHVVNK 1640
             K     P     KR+ +Q V  ++P EPEI+LKY +     ++D++  +F P++ V  +
Sbjct: 1545 AKNTTSSPCKGRAKRRRQQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFSPFVRVEKR 1604

Query: 1641 CELGAVCTIIN----------------AEEEEQTKLVRGRKGQRSLTPPPSS--TESKAL 1682
                 +CT++N                +     +       G    T P  S      +L
Sbjct: 1605 DAFTTICTVVNSPGDAPKPHRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQPRPSL 1664

Query: 1683 PASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPKRA 1742
            P SS M  GPVV+++     LVCCLC   A+++++GDL GP+YP+     LPK  P    
Sbjct: 1665 PLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYYPEH---CLPKKKP---- 1717

Query: 1743 TEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCG--GGPR 1800
                   K++ K    G+  +     E+  +  E  + A   +  R     D    G  R
Sbjct: 1718 -------KLKEKVRPEGTCEEASLPLERTLKGPECAAAATAGKPPRPDGPADPAKQGPLR 1770

Query: 1801 SLSRGLP-------CKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELP-LDSNEF 1852
            + +RGL        C     +G  E        + P       E   + P  P  ++ E 
Sbjct: 1771 TSARGLSRRLQSCYCCDGREDGGEE--------AAPADKGRKHECSKEAPAEPGGEAQEH 1822

Query: 1853 WVHEGCILWANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPC 1912
            WVHE C +W  G+YLV G+L+GLQEA+++A +M CS CQEAGAT+GC +KGC   YHYPC
Sbjct: 1823 WVHEACAVWTGGVYLVAGKLFGLQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYPC 1882

Query: 1913 AIDADCLLHEENFSVRCPKHK 1933
            A DA C+  EENFS++CPKHK
Sbjct: 1883 ASDAGCIFIEENFSLKCPKHK 1903



 Score =  181 bits (459), Expect = 6e-45
 Identities = 197/627 (31%), Positives = 270/627 (43%), Gaps = 91/627 (14%)

Query: 1   MQSFREQSSYHGNQQSYPQEVHGSSRLEEF-SPRQA------QMFQNFGGTGGSSGSSGS 53
           MQSFRE+  +HG QQ+Y Q    +SRLE +  P QA      Q              S  
Sbjct: 1   MQSFRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYE 60

Query: 54  GSGGGRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSG 113
           G  G   G AAA AA                   D Y+      P    T Q  Q RP+ 
Sbjct: 61  GGAGTPSGTAAAVAA-------------------DKYHRGSKALP----TQQGLQGRPAF 97

Query: 114 PVQSYGPPQGSSFGNQYGSEGHVGQFQA------QHSGL-GGVSHYQQDYTGPFS-PGSA 165
           P   YG    S +  +Y  E  +  + A      Q   L  GV+ Y ++     + P S 
Sbjct: 98  P--GYGVQDSSPYPGRYAGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSR 155

Query: 166 QYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
           QY +Q +      QV      L+    P PQ   QP +       +QR       A+   
Sbjct: 156 QYAEQGA------QVPFRTHSLHVQQPPPPQ---QPLAYPK----LQRQKLQNDIASPLP 202

Query: 226 LRVG-QFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAY 284
              G  F QH QS  +SS+ SS  S Q   Q   SY  S        ++     S++ A 
Sbjct: 203 FPQGTHFPQHSQSFPTSSTYSS--SVQGGGQGAHSYK-SCTAPTAQPHDRPLTASSSLAP 259

Query: 285 G--TQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQS 342
           G   Q+ ++YQ   +   +Q    Q  QQ QQQQQ  Q +H +Q  + Y N A K     
Sbjct: 260 GQRVQNLHAYQSGRLSYDQQQ---QQQQQQQQQQQALQSRHHAQETLHYQNLA-KYQHYG 315

Query: 343 QVGQ-YNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ- 400
           Q GQ Y QP+  VR+P Q++Q FSP S+ SPA SV +SPS SSTPSPLM   EN    Q 
Sbjct: 316 QQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQ 375

Query: 401 ----GSVPMGSRNRILQLMPQLSPTPS-MMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSS 455
               G+ P G  +     MP L+P+P+    S ++ A   K    + +PE  L+D  L S
Sbjct: 376 PLSTGAFPAGITDH-SHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQS 434

Query: 456 LSALSTQVANLPNTVQHMLLSDALTPQKKTSK----RPSSSKKADSCTNSEGSSQPEEQL 511
           L+AL++QV N+ NTVQ +LLS A  PQKK  K    R     K+  C + EGS    E  
Sbjct: 435 LTALTSQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHC-SPEGSGYSAEPA 493

Query: 512 KSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRL 571
            +P++E        S+  + +    LSG     + ++               A+  P R+
Sbjct: 494 GTPLSEP-PSSTPQSTHAEPQEADYLSGSEDPLERSF----------LYCNQARGSPARV 542

Query: 572 NASPAAREEATS----PGAKDMPLSSD 594
           N++  A+ E+ S        DM   SD
Sbjct: 543 NSNSKAKPESVSTCSVTSPDDMSTKSD 569



 Score = 37.4 bits (85), Expect = 0.15
 Identities = 45/179 (25%), Positives = 65/179 (36%), Gaps = 14/179 (7%)

Query: 1523 PKQEG------FPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPK 1576
            P Q+G      FP  G   S    GR  G  + Q     P PPPPQP  +P G A  +  
Sbjct: 86   PTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQA-WGAPQPPPPQPQPLPAGVAKYDEN 144

Query: 1577 PKKQR---QRRERRKPGAQ-PRKRKTKQAVPIVEPQEPEIKLKYATQPLDKTDAKNKSFY 1632
              K+      R+  + GAQ P +  +        PQ+P    K   Q L    A    F 
Sbjct: 145  LMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFP 204

Query: 1633 PYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQG 1691
               H     +     +  ++  +      +G    +S T P +    + L ASS +  G
Sbjct: 205  QGTHFPQHSQSFPTSSTYSSSVQGGG---QGAHSYKSCTAPTAQPHDRPLTASSSLAPG 260


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 271/1272 (21%), Positives = 408/1272 (32%), Gaps = 213/1272 (16%)

Query: 6    EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAA 65
            + +SY+ N+ +YP      +     SPR           GG+ GS  + + G +   +++
Sbjct: 211  QYNSYYPNRSAYPPPAPAYALS---SPR-----------GGTPGSGAAAAAGSKPPPSSS 256

Query: 66   AAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQ--RRPSGPVQSYGPPQG 123
            A+A +S +S  Q  Q F    G     AG   P  T TP   Q    PS      G P G
Sbjct: 257  ASASSSSSSFAQ--QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGG 314

Query: 124  S-SFGNQYGSEGH------------VGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQ 170
              S G Q G  G                  A  +  GG    Q+ +  P SPGS+    Q
Sbjct: 315  DYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQ--QRSHHAPMSPGSSGGGGQ 372

Query: 171  ASSQQQQ-----QQVQQLRQQLYQSHQPLPQATGQPAS-SSSHLQP-----MQRPSTLPS 219
              ++  Q      Q+ ++R Q Y    P  Q  G P+     H  P      Q P   P 
Sbjct: 373  PLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPM 432

Query: 220  SAAG----------YQLRVGQFGQHYQSSASSSSSSSF-----PSPQRFSQSGQSYDGSY 264
            +  G          Y  ++  +GQ   S       + +     P PQ+          S 
Sbjct: 433  TMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQ 492

Query: 265  NVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHP 324
              +A   Y+        Q   +Q  YS QP S    +Q+  P  +QQ   QQ PQ Q   
Sbjct: 493  TPHAQPSYQQQPQSQPPQLQSSQPPYSQQP-SQPPHQQSPAPYPSQQSTTQQHPQSQPPY 551

Query: 325  SQHVMQ--YTNAATKLPLQSQVGQ---YNQPEVPVRSPMQFHQNFSP----ISNPSPAAS 375
            SQ   Q  Y     + P  S + Q   Y QP+        + Q   P    +S  S  + 
Sbjct: 552  SQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQ 611

Query: 376  VVQSPSCSSTPSPLMQTGENLQCGQGSVP-MGSRNRILQLMPQLSPTPSMMPSPNSHAAG 434
               +PS +S+         +LQ    S+P +      L +  + + +P +  S  S + G
Sbjct: 612  ASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQG 671

Query: 435  FKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHML---LSDALTPQKKTSKRPSS 491
             +    +  P    T P L  +   S      P +V       LS A  P  +   RP S
Sbjct: 672  EQSNPAQS-PFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPS 730

Query: 492  ---------SKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSG--- 539
                     S    S     G  Q   Q+    +    G   S  +  G ++    G   
Sbjct: 731  GQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ-YSSPQPGSALSPRQPSGGQIHTGMGSYQ 789

Query: 540  QSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP-GAKDMPLSSDGNPK 598
            Q++      +GG     G  P Q   N  P  N   A      +P GA        G P 
Sbjct: 790  QNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPP 849

Query: 599  VNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLP----- 653
                  G    R +      +P G +  +      +   PP  G  ++T   ++      
Sbjct: 850  YGTLPPG----RMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAA 905

Query: 654  ---QPEPPG-----GGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSL 705
               Q  PPG      GG  G           G   GQ  +S AG     +  P    G++
Sbjct: 906  NSIQNRPPGYPNMNQGGMMG----------TGPPYGQGINSMAGM-INPQGPPYSMGGTM 954

Query: 706  RYSYKDSFGSAVPRNVSGFPQYPTG-----QEKGDFTGHGERKGRNEKFPSLLQEVLQGY 760
                 +S G A    + G              K D T   E K +     +   E +   
Sbjct: 955  A---NNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKL 1011

Query: 761  HH---HPDR-----RYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGSLL 812
            +     P+R     RY   T+E         G T    +  +  +L    +  K IG L 
Sbjct: 1012 YELGGEPERKMWVDRYLAFTEE------KAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLT 1065

Query: 813  ENPHWGPWER--------KSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERR 864
            +      W           SSS A  +K+  +        FE + +     P    +   
Sbjct: 1066 QVNKNKKWRELATNLNVGTSSSAASSLKKQYI---QCLYAFECKIERGEDPPPDIFA--- 1119

Query: 865  SVICDISPLRQIVRDPGAHSLGHM-------SADTRIGRNDRLNPTL------SQSVILP 911
                D    +  ++ P     G M       S  + +     L P        SQ   LP
Sbjct: 1120 --AADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLP 1177

Query: 912  GGLVSMETKLKSQSGQIKEEDFEQSKSQASF--NNKKSGDHCHPPSIKHESYRGNASPGA 969
            G          S+S  +  +D     S ++F   N  + +  + PS+      G  S   
Sbjct: 1178 G---------MSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMS--- 1225

Query: 970  ATHDSLSDYGPQDSRPTPMRRVPGR---VGGREGMRGRSPSQYHDFAEKLKMSPGRSRGP 1026
                    Y P       MR+ PG    +   +G  G     Y            R+ GP
Sbjct: 1226 --------YEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY-----------SRAAGP 1266

Query: 1027 GGDPHHMNP--HMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLH 1084
            G     M P  H  +    +R        P       A   N       +P++G+ S   
Sbjct: 1267 GLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMP---SNPDSGMYSPSR 1323

Query: 1085 YKRQMYQQQPEEYKDWSSG-SAQGVIAAAQHRQEGPRKSPRQQQF----LDRVRSPLKND 1139
            Y  Q  QQQ + +  + +  S QG  + +    +      +QQQ     +D    P    
Sbjct: 1324 YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKR 1383

Query: 1140 KDGMMYGPPVGT 1151
             +G MY  P  T
Sbjct: 1384 HEGEMYSVPYST 1395



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 94/408 (23%), Positives = 147/408 (36%), Gaps = 86/408 (21%)

Query: 50   SSGSGSGGGR-----RGAAAAAAAMASETSGHQGYQG----FRKEAGDFYYMAGNKDPVT 100
            SSG G  GG      R A      +A     H  Y G     R E G      G +  ++
Sbjct: 1247 SSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPG-----IGPEGNMS 1301

Query: 101  TGTPQP---PQRRPSGPVQ-SYGPPQGS--------SFGNQYGSEG----------HVGQ 138
            TG PQP   P    SG    S  PPQ          S+GNQ+ ++G              
Sbjct: 1302 TGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTM 1361

Query: 139  FQAQHS----------GLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLY 188
            +Q Q            G     H  + Y+ P+S G  Q QQQ     Q Q   Q      
Sbjct: 1362 YQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQ-----Q 1416

Query: 189  QSHQPLPQ-------ATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASS 241
            Q+ QP PQ           PA++++  +  +RP+  P +   +     QFG+   S+   
Sbjct: 1417 QAAQPSPQQDVYNQYGNAYPATATAATE--RRPAGGPQNQFPF-----QFGRDRVSAPPG 1469

Query: 242  SSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSY-QPQSMKNF 300
            +++     PQ     G     +     G+ ++G N             Y+Y   QS  + 
Sbjct: 1470 TNAQQNMPPQ--MMGGPIQASAEVAQQGTMWQGRN----------DMTYNYANRQSTGSA 1517

Query: 301  EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLP---LQSQVGQYNQPEVPVRSP 357
             Q     G  +  +     Q+   + H   + +  T+ P     + V    +P      P
Sbjct: 1518 PQGPAYHGVNRTDEMLHTDQR---ANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQP 1574

Query: 358  MQFHQNFSP-ISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVP 404
                QN  P +S+P+P    +++ + S + SP + +G  +Q     VP
Sbjct: 1575 PPSMQNHIPQVSSPAPLPRPMENRT-SPSKSPFLHSGMKMQKAGPPVP 1621



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 163/799 (20%), Positives = 263/799 (32%), Gaps = 95/799 (11%)

Query: 39  QNFGGTGGSSGSSGSGSGGG---------RRGAAAAAAAMASETSGHQGYQGFRKEAG-- 87
           Q+   + G  G  G+GSGGG           G A    A+ +  +   G  G     G  
Sbjct: 74  QDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133

Query: 88  -DFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGL 146
              +  A    P   G  QP  R PS    +      + F  Q+G +   G    Q  G 
Sbjct: 134 APPHSAAAALPPPAYGFGQPYGRSPS----AVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189

Query: 147 GGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSS 206
           GG+  Y          G   +Q  +    +             S +     +G  A++ S
Sbjct: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGS 249

Query: 207 HLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQ-----RFSQSGQSYD 261
              P    S   SS++  Q R G  G    S+A   +     +P          S + Y 
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309

Query: 262 G--SYNVNAGSQYEGHNVG---SNAQAYGTQSNYSYQPQSMKNFEQ----AKIPQGTQQG 312
           G    + + G Q  G   G     +Q +G  +  +    +    +Q    A +  G+  G
Sbjct: 310 GYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG 369

Query: 313 QQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVG--QYNQPEVPVRSPMQFH--------- 361
             Q   +  Q PS  + Q      K+  Q   G   Y+Q + P   P Q H         
Sbjct: 370 GGQPLARTPQ-PSSPMDQ----MGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGS 424

Query: 362 ---QNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRN--RILQLMP 416
              Q + P++    A S +   S +    P  Q G +    QG  P  ++      Q  P
Sbjct: 425 QTPQRY-PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQP 483

Query: 417 QLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHML-- 474
             S  P   PS   HA        +  P+ +   P L S     +Q  + P   Q     
Sbjct: 484 PYSQQP---PSQTPHAQP----SYQQQPQSQ--PPQLQSSQPPYSQQPSQPPHQQSPAPY 534

Query: 475 -LSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGER 533
               + T Q   S+ P S  +A S    +   QP     S  A         S +    +
Sbjct: 535 PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQ 594

Query: 534 VRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSS 593
            R    Q  S D+     +S  + +S   G ++    L + P++  +  S    D+P+ +
Sbjct: 595 QRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPD-LSGSIDDLPMGT 653

Query: 594 DGNPKVNEKTVGVIVSREAMTGRVEKPGGQD-----KGSQEDDPAATQRPPSNGGAKE-- 646
           +G       T G+  S+   +   + P          G +   P+    P S   ++   
Sbjct: 654 EGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGP 713

Query: 647 TSHASLP---QPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPG 703
            S A++P    P  P  G S    +   N +   +  G    +   P ++     S  PG
Sbjct: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYS-----SPQPG 768

Query: 704 SLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHH 763
           S   S +   G  +   +  + Q       G +   G + G    +P         Y+  
Sbjct: 769 S-ALSPRQPSGGQIHTGMGSYQQ----NSMGSYGPQGGQYGPQGGYPR-----QPNYNAL 818

Query: 764 PDRRYSRSTQEHQGMAGSL 782
           P+  Y  +     GMAG +
Sbjct: 819 PNANYPSA-----GMAGGI 832



 Score = 32.3 bits (72), Expect = 4.7
 Identities = 66/292 (22%), Positives = 100/292 (34%), Gaps = 54/292 (18%)

Query: 1357 QKITSPNIRRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKR------KG 1410
            Q +TSP+   SA       GGD           SG P+ G      AD+  +        
Sbjct: 297  QLLTSPS---SARGYQGYPGGDY----------SGGPQDGGAGKGPADMASQCWGAAAAA 343

Query: 1411 EVASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQ 1470
              A+     A Q  H     P SS      +    +  +  + +   +  P   T+  SQ
Sbjct: 344  AAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ 403

Query: 1471 KPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVT--ISPKQEGF 1528
            +    QG P G   G     +P      P G   P+  P   +    +    +S  Q+  
Sbjct: 404  Q----QGPPSGPQQGHG---YPGQ----PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQ-I 451

Query: 1529 PPKGYF-PSGKKKGRPIGSVNKQK---KQQQPPPPPPQPPQIPEGSADGEPKPKKQ---- 1580
            PP G   PSG  +       N+Q    +QQQPP     P Q P      + +P+ Q    
Sbjct: 452  PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511

Query: 1581 -----------RQRRERRKPGAQPRKRKTKQAVPIVEP--QEPEIKLKYATQ 1619
                        Q   ++ P   P ++ T Q  P  +P   +P+ +  Y  Q
Sbjct: 512  QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQ 563



 Score = 32.3 bits (72), Expect = 4.7
 Identities = 37/156 (23%), Positives = 59/156 (37%), Gaps = 44/156 (28%)

Query: 1465 TSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPK 1524
            + T  + P + QGR   ++GG +      ++ +PP G                       
Sbjct: 424  SQTPQRYPMTMQGRAQSAMGGLSY-----TQQIPPYG----------------------- 455

Query: 1525 QEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRR 1584
            Q+G  P GY   G++   P  +      QQQ PP   QPP     S     +P  Q+Q  
Sbjct: 456  QQG--PSGY---GQQGQTPYYNQQSPHPQQQQPPYSQQPP-----SQTPHAQPSYQQQ-- 503

Query: 1585 ERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620
                P +QP + ++ Q     +P +P  +   A  P
Sbjct: 504  ----PQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP 535


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 293/1329 (22%), Positives = 430/1329 (32%), Gaps = 195/1329 (14%)

Query: 8    SSY--HGNQ--QSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGR---- 59
            SSY  HG++  QS   E HGSS     S   +   Q+  G+  S G    GSG G+    
Sbjct: 955  SSYEQHGSRSGQSSRSEQHGSS-----SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1009

Query: 60   -RGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSY 118
             RG   + +  +S    ++   G+    G +   +G+    ++G      R  SG    Y
Sbjct: 1010 SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGH----SSGLGHRESR--SGQSSGY 1063

Query: 119  GPPQGSSFGNQYGSEGHVGQFQAQHSGLG--GVSHYQQDYTGPFSPGSAQ---YQQQASS 173
            G   GSS G+   + G  G    Q S  G  G S  Q    G    GS+Q   Y +Q S 
Sbjct: 1064 GQ-HGSSSGHS-STHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1121

Query: 174  QQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQ 233
              Q     Q      QS       +G   SSSS     Q  S L  S+         FG 
Sbjct: 1122 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG----QHGSGLGESSG--------FGH 1169

Query: 234  HYQSSASSSSSSSFPSPQRFSQSGQSYD-GSYNVNAGSQYEGHNVGSNAQAYGTQSNYSY 292
            H  SS  SSS S     Q  S SG S   G +   +G    G   GS++   G+ S+Y  
Sbjct: 1170 HESSSGQSSSYS-----QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSS---GSSSHYGQ 1221

Query: 293  QPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQ 343
                 +         G Q       P + +H S         QH      ++++ P +S+
Sbjct: 1222 HGSGSRQ----SSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 1277

Query: 344  VGQ---YNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ 400
             G    + Q E        + Q+    S      S  Q  S S   S   Q G +     
Sbjct: 1278 SGHSSVFGQHESGSGHSSAYSQHG---SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 1334

Query: 401  GSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAG---FKGFGLEGVPEKRLTDPGLSSLS 457
                 GS +       +        PS   H +G      +G  G      +  G SS S
Sbjct: 1335 SYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHG------SGSGWSSSS 1388

Query: 458  ALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCT---NSEGSSQPEEQLKSP 514
                  +   +   H                 SSS ++  CT   +  G S   EQ  S 
Sbjct: 1389 GRHGSGSGQSSGFGH---------------HESSSWQSSGCTQHGSGSGHSSSYEQHGSR 1433

Query: 515  MAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNAS 574
              +S  G    SS        Q    S  S    + G+      SP++G        + S
Sbjct: 1434 SGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR-------HGS 1486

Query: 575  PAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKG-SQEDDPA 633
             + +  + SP       SS   P  +        S  +  G  E   GQ  G  Q    +
Sbjct: 1487 GSGQSSSYSPYGSGSGWSSSRGPYESGS------SHSSGLGHRESRSGQSSGYGQHGSSS 1540

Query: 634  ATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNS-----NHNGEGNGQS-GHSA 687
                     G+     +S  Q     G  S   ++G  +S        G G+GQS GH  
Sbjct: 1541 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1600

Query: 688  AGPGFTSRTEPS---KSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ-EKGDFTGHGERK 743
             G G  SR  PS      GS R S     GS +  + SGF  + +   +   ++ HG   
Sbjct: 1601 RGSG--SRQSPSYGRHGSGSGRSSSSGQHGSGLGES-SGFGHHESSSGQSSSYSQHGSGS 1657

Query: 744  GRNEKF---PSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELAS 800
            G +  +    S   +  +G  H    R S    +H   +    G  R     S + +  S
Sbjct: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQG---SGSGQSPS 1714

Query: 801  RGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPG--- 857
            RG     +G    +   G    +SSS  P   +   +       F      S H      
Sbjct: 1715 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV-----FGQHESGSGHSSAYSQ 1769

Query: 858  --------------GSLSERRSVICDISPLRQIVRDPGAHSLGHMSADT--RIGRNDRLN 901
                          GS S + S               G H  G   + +  + G     +
Sbjct: 1770 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 1829

Query: 902  PTLSQSVILPG------------GLVSMETKLKSQSGQIKEEDFEQSKS--QASFNNKKS 947
            P+  +     G            G  S   +  S SGQ       +S S   + +    S
Sbjct: 1830 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGS 1889

Query: 948  GDHCHPPSIKHESYRGNASPG---AATHDSLSDYGPQDS----------RPTPMRRVPGR 994
            G        +H S  G +S G    ++  S S YG   S            +   + P  
Sbjct: 1890 GSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1949

Query: 995  VGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHH--MNPHMTFSERANRSSLHTPF 1052
              GR G      S Y  +      S  R     G  H   +    + S +++    H   
Sbjct: 1950 SRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSS 2009

Query: 1053 SPNSETLASAYHANTRAHAYGDPNAGL-NSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAA 1111
            S +S T      A+ ++ + G   A    S  H +      Q   Y    SGS Q    +
Sbjct: 2010 SGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ----S 2065

Query: 1112 AQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGT-----YHDPSAQEAGRCLMS 1166
              H Q G     RQ     R  S          +GP +G      +H+ S+ ++      
Sbjct: 2066 PGHGQRG--SGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQH 2123

Query: 1167 SDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSS-GPPGMSSQKRYGPPHETDGHGLAE 1225
              G  +     +HGS+  Q S  +    +S + S  G  G  S++  G  H   G G   
Sbjct: 2124 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG--HGRQGSGSGH 2181

Query: 1226 ATQSSKPGS 1234
            +    + GS
Sbjct: 2182 SPSRGRHGS 2190



 Score = 84.7 bits (208), Expect = 8e-16
 Identities = 297/1345 (22%), Positives = 433/1345 (32%), Gaps = 201/1345 (14%)

Query: 8    SSY--HGNQ--QSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGR---- 59
            SSY  HG++  QS   E HGSS     S   +   Q+  G+  S G    GSG G+    
Sbjct: 1425 SSYEQHGSRSGQSSRGERHGSS-----SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1479

Query: 60   -RGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSY 118
             RG   + +  +S  S +    G+    G   Y +G+      G       R S   QS 
Sbjct: 1480 SRGRHGSGSGQSSSYSPYGSGSGWSSSRGP--YESGSSHSSGLG------HRESRSGQSS 1531

Query: 119  GPPQGSSFGNQYGSEGHVGQFQAQHSGLG--GVSHYQQDYTGPFSPGSAQ---YQQQASS 173
            G  Q  S      + G  G    Q S  G  G S  Q    G    GS+Q   Y +Q S 
Sbjct: 1532 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1591

Query: 174  QQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQ 233
              Q     Q      QS       +G   SSSS     Q  S L  S+         FG 
Sbjct: 1592 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG----QHGSGLGESSG--------FGH 1639

Query: 234  HYQSSASSSSSSSFPSPQRFSQSGQSYD-GSYNVNAGSQYEGHNVGSNAQA---YGTQSN 289
            H  SS  SSS S     Q  S SG S   G +   +G    G   GS++++   YG   +
Sbjct: 1640 HESSSGQSSSYS-----QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS 1694

Query: 290  YSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPL 340
             S Q              G Q     Q P + +H S         QH      ++++ P 
Sbjct: 1695 GSRQSSG----------HGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 1744

Query: 341  QSQVGQ---YNQPEVPVRSPMQFHQNFSP----ISNPSPAASVVQSPSCSSTPSPLMQTG 393
            +S+ G    + Q E        + Q+ S      S     ++  QS +     S   Q+ 
Sbjct: 1745 ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 1804

Query: 394  ENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGF----KGFGLEGVPEKRLT 449
             + Q G GS    S  +      Q SP+     S + H++ +     G G      +  +
Sbjct: 1805 SHGQHGSGSSQSSSYGQQGSGSGQ-SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 1863

Query: 450  DPGLSS-LSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPE 508
              G SS      +         QH   S   +  ++   R   S + +   +S GSS   
Sbjct: 1864 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSY 1923

Query: 509  EQLKSPMAESLDGGCSSSSEDQG---ERVRQLSGQSTSSDTTYKGGASE--------KAG 557
             Q  S   +SL  G   S   Q     R R  SG   SS     G  S         ++G
Sbjct: 1924 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESG 1983

Query: 558  SSPAQGAQNEPPRLNASPAAREEATSPG------------AKDMPLSSDGNPKVNEKTVG 605
            S  + G  +   R   S    +  +S G             +       G       + G
Sbjct: 1984 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHG 2043

Query: 606  VIVSREAMT---GRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGG 662
               S  + +   GR     GQ  G  +    + Q P        +  +S      PG G 
Sbjct: 2044 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGE 2103

Query: 663  SKG-----NKNGDNNS-NHNGEGNGQS---GHSAAGPGFTSRTE--PSKSPGSLRYSYKD 711
            S G     + +G ++S + +G G+G S   G   +  G +SR E   S S  S RY    
Sbjct: 2104 SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHG 2163

Query: 712  S---FGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRY 768
            S     S   R  SG    P+    G  +GH    G++            G      R  
Sbjct: 2164 SGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHG----------SGSGRSSSRGP 2213

Query: 769  SRSTQEHQGMAGSLEGTTRPNVLVSQ----TNELASRGLLNKSIGSLLENPHWGPWERKS 824
              S   H  + G  E  +  +   SQ    +    S+G    + G          ++++ 
Sbjct: 2214 YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS------STFDQEG 2267

Query: 825  SSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAH- 883
            SST                      QSS+H   GS S + S               G H 
Sbjct: 2268 SSTG---------------------QSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 2306

Query: 884  -SLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKS--QA 940
               GH S+  + G                 G  S   +  S SGQ       +S S   +
Sbjct: 2307 SGSGHSSSYGQHGSG--------------SGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352

Query: 941  SFNNKKSGDHCHPPSIKHESYRGNASPG---AATHDSLSDYGPQDS----------RPTP 987
             +    SG        +H S  G +S G    ++  S S YG   S            + 
Sbjct: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412

Query: 988  MRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSS 1047
              + P    GR G      S Y  +      S  R     G  H        S     S 
Sbjct: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472

Query: 1048 LHTPFSPNSETLASAYHANTRAHAYGDPNAGLN---SQLHYKRQMYQQQPEEYKDWSSGS 1104
                 S +  +     H +T   +      G +   S  H +      Q   Y    SGS
Sbjct: 2473 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2532

Query: 1105 AQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVG-TYHDPSAQEAGRC 1163
             Q        R  G R+SP   +          + + G   G   G  +H+ S+ ++   
Sbjct: 2533 GQS--PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSY 2590

Query: 1164 LMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSS-GPPGMSSQKRYGPPHETDGHG 1222
                 G  +     +HGS+  Q S  +    +S + S  G  G  S++  G  H   G G
Sbjct: 2591 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG--HGRQGSG 2648

Query: 1223 LAEATQSSKPGSVMLRLPGQEDHSS 1247
              ++    + GS +        H S
Sbjct: 2649 SGQSPSRGRHGSGLGHSSSHGQHGS 2673



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 292/1384 (21%), Positives = 436/1384 (31%), Gaps = 201/1384 (14%)

Query: 3    SFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGA 62
            S+  QSS +G Q S   +  G  +    S +     Q+  G+G SS +   GSG G+   
Sbjct: 171  SYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSG 230

Query: 63   AAAAAAMASETSGH----------QGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPS 112
             +   + + ++SG+           GY      +G      G +   ++G+     +  S
Sbjct: 231  FSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQ--SSRGERHRSSSGSSSSYGQHGS 288

Query: 113  GPVQSYGPPQ----------------GSSFGNQYG----------SEGHVGQFQAQHSGL 146
            G  QS G  +                GS   + +G          S GH      Q SG 
Sbjct: 289  GSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGF 348

Query: 147  G-------------------GVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQL 187
            G                   G S  Q  +       S+  Q  +SS+Q     Q      
Sbjct: 349  GQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASR 408

Query: 188  YQS--------------HQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQ 233
            + S              H      +GQ  SS  H     R S+     +G     G FG 
Sbjct: 409  HSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSG-FGH 467

Query: 234  HYQSSASSSSSSSFPSPQRFSQSGQSY-DGSYNVNAGSQYEGHNVGSNAQAYGTQSNY-S 291
            H  SS  SS  +     Q  S SG S   G +   +G    G   GS+A   G+ S+Y  
Sbjct: 468  HESSSEHSSGYT-----QHGSGSGHSSGHGQHGSRSGQSSRGERQGSSA---GSSSSYGQ 519

Query: 292  YQPQSMKNFEQAKIPQGTQQ------GQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVG 345
            +   S ++   ++   G+ Q      G+ +   +Q      H      ++++ P +S  G
Sbjct: 520  HGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSG 579

Query: 346  Q---YNQPEVPVRSPMQFHQNFSPISNPSP----AASVVQSPSCSSTPSPLMQTGENLQC 398
                    E        + Q+ S   + S      ++  QS SC    +   Q+  + Q 
Sbjct: 580  HSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQH 639

Query: 399  GQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGF---KGFGLEGVPEKRLTDPGLSS 455
            G GS    SR        Q        PS   H + F     +G  G      +  G SS
Sbjct: 640  GSGS-SQSSR------YGQQGSGSGQSPSRGRHGSDFGHSSSYGQHG------SGSGWSS 686

Query: 456  LSALSTQVANLPNTVQHML---LSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLK 512
             +     V+   +   H      S   +     S   S  +K  S   S  SS+ E+   
Sbjct: 687  SNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGS--RSGQSSRSEQHGS 744

Query: 513  SPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLN 572
            S    S  G   S S       RQ SG   S      G +S  + S    G+        
Sbjct: 745  SSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTS----C 800

Query: 573  ASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDP 632
            +S     E+ S  A        G+ +      G      +  GR     GQ   S + D 
Sbjct: 801  SSSCGHYESGSGQASGFGQHESGSGQ-GYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDS 859

Query: 633  AATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDN-NSNHNGEGNGQS---GHSAA 688
            ++ Q          + HAS        G G  G+ +G +      G G+GQS   G   +
Sbjct: 860  SSGQSSSYGQHESASHHAS--------GRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGS 911

Query: 689  GPGFTSRT--EPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ-EKGDFTGHGERKG- 744
            G G +S +    S S  S  + +K S G +     SG+ Q+ +G      +  HG R G 
Sbjct: 912  GSGRSSSSGRHGSGSGQSSGFGHKSSSGQS-----SGYTQHGSGSGHSSSYEQHGSRSGQ 966

Query: 745  --RNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRG 802
              R+E+  S          H    R S    +H   +G     +R            S  
Sbjct: 967  SSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR--------GRHGSGS 1018

Query: 803  LLNKSIGSLLENPHW----GPWERKS--SSTAPEMKQINLTDYPIPRKFEIEPQSSAHEP 856
              + S G       W    GP+E  S  SS     +  +       +       SS H  
Sbjct: 1019 GQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ 1078

Query: 857  GGSLSERRSVICDISPLRQIVRDPGAHSLG--HMSADTRIGRNDRLNPTLSQSVILPGGL 914
             GS S + S               G H  G    S   R G     +P   Q      G 
Sbjct: 1079 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR-----GS 1133

Query: 915  VSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDS 974
             S ++    + G          +  +         H    S +  SY  + S    +   
Sbjct: 1134 GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS--- 1190

Query: 975  LSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPH--- 1031
             S YG   SR     R     G R G    S S Y       + S G  R   G  H   
Sbjct: 1191 -SGYGQHGSRSGQSSR-----GERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPS 1244

Query: 1032 ---------HMNPHMTFSERANRSSLHTPF-SPNSETLASAYHANTRAHAYGDPNAGLNS 1081
                     H + H      + RSS   P+ S +  +     H +   H+      G  S
Sbjct: 1245 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 1304

Query: 1082 QLHYKRQMYQQQPEEYKDW-SSGSAQGVIAAAQHRQEGPRKSPRQ-QQFLDRVRSPLKND 1139
                 +  +     +   +   GS+ G  ++  HR  G  +S    +      +SP +  
Sbjct: 1305 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRG- 1363

Query: 1140 KDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAK 1199
                 +G   G         +G    SS G    G     G    + S W  S  T    
Sbjct: 1364 ----RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGS 1419

Query: 1200 SSGPPGMSSQ--KRYGPPHETDGHGLAEATQSS--KPGSVMLRLPGQEDH---SSQNPLI 1252
             SG      Q   R G     + HG +  + SS  + GS   +  G   H   S Q+P  
Sbjct: 1420 GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1479

Query: 1253 MRRR 1256
             R R
Sbjct: 1480 SRGR 1483



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 282/1275 (22%), Positives = 418/1275 (32%), Gaps = 214/1275 (16%)

Query: 22   HGSSRLEEFSPRQAQMF-QNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGHQGYQ 80
            HGSS  +  S  Q +   ++  G G  S  SG   G G+RG+ +      S +SG  G  
Sbjct: 390  HGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQ----SPSSGQHG-T 444

Query: 81   GFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQGSSFGN-QYGSE-GHVGQ 138
            GF + +    Y++G+      G  +      SG  Q +G   G S G+ Q+GS  G   +
Sbjct: 445  GFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQ-HGSGSGHSSGHGQHGSRSGQSSR 503

Query: 139  FQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQAT 198
             + Q S  G  S Y Q  +G  S  S  + +  S   Q     + R +            
Sbjct: 504  GERQGSSAGSSSSYGQHGSG--SRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPH 561

Query: 199  GQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQ---FGQHYQSSASSSSSSSFPSPQRFSQ 255
            G  +  SS   P +  S   S     + R GQ   +GQH  SS  SS+       Q  S 
Sbjct: 562  GYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHG-----QHGST 616

Query: 256  SGQSYD-GSYNVNAG--SQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQG 312
            SGQS   G +   +G  S +  H  GS+                          Q ++ G
Sbjct: 617  SGQSSSCGQHGATSGQSSSHGQHGSGSS--------------------------QSSRYG 650

Query: 313  QQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSP 372
            QQ     Q     +H   + ++       S  GQ+        S   +  +  P  + S 
Sbjct: 651  QQGSGSGQSPSRGRHGSDFGHS-------SSYGQHG-------SGSGWSSSNGPHGSVSG 696

Query: 373  AASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHA 432
             +S     S S   S   Q G       G    GSR+       Q   +  +  S   H 
Sbjct: 697  QSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG 756

Query: 433  AGF---KGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRP 489
            +G     G G +G                  +   + P+ V+H     +        +  
Sbjct: 757  SGSHQSSGHGRQG------------------SGSGHSPSRVRH---GSSSGHSSSHGQHG 795

Query: 490  SSSKKADSCTNSE-GSSQP----EEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSS 544
            S +  + SC + E GS Q     + +  S    S  G  S     QG R    SGQS+SS
Sbjct: 796  SGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQG-RHGSTSGQSSSS 854

Query: 545  DTTYKGGASEKAGSSPAQGAQNEPPRLNASPAARE---EATSPGAKDMPLSSDGNPKVNE 601
                 G     +G S + G Q+E    +AS   R       SPG       S  +P    
Sbjct: 855  -----GQHDSSSGQSSSYG-QHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGR 908

Query: 602  KTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGG 661
               G    R + +GR     GQ  G      +      +  G+     +S  Q     G 
Sbjct: 909  HGSGS--GRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQ 966

Query: 662  GSKGNKNGDNNSN-----HNGEGNGQS-GHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGS 715
             S+  ++G ++ +      +G G+ QS GH   G G      PS+           S+G 
Sbjct: 967  SSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGP 1026

Query: 716  AVPRNVSGF--PQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQ 773
               R+ SG+   + P     G  +G G R+ R+ +          GY  H       ST 
Sbjct: 1027 Y--RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ--------SSGYGQHGSSSGHSSTH 1076

Query: 774  EHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQ 833
               G               S + + +S G    S G    +   G    +SS        
Sbjct: 1077 GQHG---------------STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG----- 1116

Query: 834  INLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLG-HMSADT 892
                     R+     QS  H   GS S +       SP           S G H S   
Sbjct: 1117 ---------RQGSGSGQSPGHGQRGSGSRQ-------SP-----------SYGRHGSGSG 1149

Query: 893  RIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCH 952
            R   + +    L +S     G    E    S SGQ            +S++   SG    
Sbjct: 1150 RSSSSGQHGSGLGES----SGFGHHE----SSSGQ-----------SSSYSQHGSGSGHS 1190

Query: 953  PPSIKHESYRGNASPG---AATHDSLSDYGP--QDSRPTPMRRVPGRVGGREGMRGRSPS 1007
                +H S  G +S G    ++  S S YG     SR +      G   G    RGR  S
Sbjct: 1191 SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS 1250

Query: 1008 QYHDFAEKLKMSPG----RSRGP----GGDPHHMNPHMTFSERANRSSLHTPFSPNSETL 1059
                 +   +   G     SRGP     G       H + S  ++  S H   S +    
Sbjct: 1251 GLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG--SGSGHFC 1308

Query: 1060 ASAYHANTRAHAYGDPNAGLN---SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQ 1116
            +   H +T   +      G +   S  +  R     Q   Y    +GS Q          
Sbjct: 1309 SQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSG 1368

Query: 1117 EGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGME 1176
             G   S  Q        S       G       G +H+ S+ ++  C     G  +    
Sbjct: 1369 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG-HHESSSWQSSGCTQHGSGSGHSSSY 1427

Query: 1177 LKHGSQKLQESCWDLSRQTSPAKSS-GPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSV 1235
             +HGS+  Q S  +    +S + SS G  G  S++  G      G G + +    + GS 
Sbjct: 1428 EQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS- 1486

Query: 1236 MLRLPGQEDHSSQNP 1250
                 G    SS +P
Sbjct: 1487 -----GSGQSSSYSP 1496



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 277/1339 (20%), Positives = 424/1339 (31%), Gaps = 149/1339 (11%)

Query: 12   GNQQSYPQEVHGSSRLEEFSPR-----QAQMFQNFGGTGGSSGSSGSGSGGG------RR 60
            G+  SY Q   GS       P      Q+  F +  G+G SSG S  GSG        + 
Sbjct: 670  GHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKH 729

Query: 61   GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQR----RPSGPVQ 116
            G+ +  ++ + +     G      + G   + +       +G+   P R      SG   
Sbjct: 730  GSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSS 789

Query: 117  SYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQ 176
            S+G  Q  S  +   S GH      Q SG G   H      G    GSA     +  +  
Sbjct: 790  SHG--QHGSGTSCSSSCGHYESGSGQASGFG--QHESGSGQGYSQHGSASGHFSSQGRHG 845

Query: 177  QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLR---VGQ--- 230
                Q      + S      + GQ  S+S H     R  +    + G+  R    GQ   
Sbjct: 846  STSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPS 905

Query: 231  FGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAG--SQYEGHNVGS----NAQAY 284
            +G+H   S  SSSS      +  S SGQS    +  ++G  S Y  H  GS    + + +
Sbjct: 906  YGRHGSGSGRSSSSG-----RHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQH 960

Query: 285  GTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQV 344
            G++S  S + +   +   +    G      +Q     QH S       +  +  P + + 
Sbjct: 961  GSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG------SGQSPSPSRGRH 1014

Query: 345  GQ---YNQPEVPVRSPMQFHQNFSPISNPSPAASVV-QSPSCSSTPSPLMQTGENLQCGQ 400
            G     +    P RS   +  +  P  + S  +S +    S S   S   Q G +     
Sbjct: 1015 GSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 1074

Query: 401  GSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFK---GFGLEGVPEKRLTDPGLSSLS 457
                 GS +       Q   +     S   H +G     G+G +G    +   PG     
Sbjct: 1075 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ--SPGHGQRG 1132

Query: 458  ALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAE 517
            + S Q    P+  +H   S   +   +       S       +S G S    Q  S    
Sbjct: 1133 SGSRQS---PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1189

Query: 518  SL---DGGCSSSSEDQGERVRQLSGQST--------SSDTTYKGGASEKAGSSPAQGAQN 566
            S      G  S    +GER    SG S+        S  ++  G     +G SP++G   
Sbjct: 1190 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 1249

Query: 567  EPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPG----- 621
                 ++S       +   +   P  S      +    G   S    +    + G     
Sbjct: 1250 SGLGHSSSHGQHGSGSGRSSSRGPYESRSG---HSSVFGQHESGSGHSSAYSQHGSGSGH 1306

Query: 622  ----GQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNG 677
                GQ   +        Q   S G +    H      +  G G          +   +G
Sbjct: 1307 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHG 1366

Query: 678  EGNGQS---GHSAAGPGFTSRT--EPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ- 731
             G+G S   G   +G G++S +    S S  S  + + +S         SG  Q+ +G  
Sbjct: 1367 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW----QSSGCTQHGSGSG 1422

Query: 732  EKGDFTGHGERKG---RNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRP 788
                +  HG R G   R E+  S          H    R S    +H   +G     +R 
Sbjct: 1423 HSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 1482

Query: 789  NVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAP----EMKQINLTDYPIPRK 844
                S + + +S        G        GP+E  SS ++     E +    + Y   + 
Sbjct: 1483 RH-GSGSGQSSSYSPYGSGSGWSSSR---GPYESGSSHSSGLGHRESRSGQSSGYG--QH 1536

Query: 845  FEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLG--HMSADTRIGRNDRLNP 902
                  SS H   GS S + S               G H  G    S   R G     +P
Sbjct: 1537 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1596

Query: 903  TLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYR 962
               Q      G  S ++    + G          +  +         H    S +  SY 
Sbjct: 1597 GHGQR-----GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1651

Query: 963  GNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGR 1022
             + S    +    S YG   SR     R     G R G   RS S+Y       + S G 
Sbjct: 1652 QHGSGSGHS----SGYGQHGSRSGQSSR-----GERHGSSSRSSSRYGQHGSGSRQSSGH 1702

Query: 1023 SR---GPGGDPH---------HMNPHMTFSERANRSSLHTPF-SPNSETLASAYHANTRA 1069
             R   G G  P          H + H      + RSS   P+ S +  +     H +   
Sbjct: 1703 GRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSG 1762

Query: 1070 HA-----YGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPR 1124
            H+     +G  +    SQ  +     Q    + +  S+G +    +  QH     + S  
Sbjct: 1763 HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS---SHGQHGSGSSQSSSY 1819

Query: 1125 QQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKL 1184
             QQ     +SP +       +G   G         +G    SS G    G     G    
Sbjct: 1820 GQQGSGSGQSPSRG-----RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1874

Query: 1185 QESCWDLSRQTSPAKSSGPPGMSSQ--KRYGPPHETDGHGLAEATQSS--KPGSVMLRLP 1240
            + S W  S  T     SG      Q   R G     + HG +  + SS  + GS   +  
Sbjct: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSL 1934

Query: 1241 GQEDH---SSQNPLIMRRR 1256
            G   H   S Q+P   R R
Sbjct: 1935 GHGQHGSGSGQSPSPSRGR 1953



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 285/1330 (21%), Positives = 423/1330 (31%), Gaps = 136/1330 (10%)

Query: 7    QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSG--SSGSGSGGGRRGAAA 64
            +SS  G   S   E  G    E  S + +   Q+  G+G SSG    GS SG   RG   
Sbjct: 1150 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 1209

Query: 65   AAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQ-SYGPPQG 123
             +++ +S   G  G  G R+ +G     +G+    + G         S   Q   G  + 
Sbjct: 1210 GSSSGSSSHYGQHG-SGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRS 1268

Query: 124  SSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQL 183
            SS G      GH   F    SG G  S Y Q  +G  S       Q  S+  Q     Q 
Sbjct: 1269 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG--SGHFCSQGQHGSTSGQSSTFDQE 1326

Query: 184  RQQLYQSHQPLPQATGQPASSSSHLQPM---QRPST-LPSSAAGYQLRVGQFGQ------ 233
                 QS     + +G   SS          Q PS     S +G+    GQ G       
Sbjct: 1327 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1386

Query: 234  ---HYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNY 290
                + S +  SS         +  SG +  GS + ++ S YE H   S   + G +   
Sbjct: 1387 SSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSS-YEQHGSRSGQSSRGERHGS 1445

Query: 291  SYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQ--HVMQYTNAATKLPLQSQVGQYN 348
            S    S      +   Q    GQ      Q   PS+  H      +++  P  S  G ++
Sbjct: 1446 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG-WS 1504

Query: 349  QPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPL-----MQTGENLQCGQGSV 403
                P  S            + S  +S       SS  S         +G++  CGQ   
Sbjct: 1505 SSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1564

Query: 404  PMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFK---GFGLEGVPEKRLTDPGLSSLSALS 460
              G  +                 S   H +G     G+G +G    +   PG     + S
Sbjct: 1565 SSGQSS-----------------SHGQHGSGSSQSSGYGRQGSGSGQ--SPGHGQRGSGS 1605

Query: 461  TQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLD 520
             Q    P+  +H   S   +   +       S       +S G S    Q  S    S  
Sbjct: 1606 RQS---PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 1662

Query: 521  GGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREE 580
             G   S   Q  R  +    S SS    + G+    GS  + G   +      SP+    
Sbjct: 1663 YGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS----GSRQSSGHGRQGSGSGQSPSRGRH 1718

Query: 581  ATSPGAKDMPLSSDGNPKVNEKTVGVIVSRE---AMTGRVEKPGGQDKG-SQEDDPAATQ 636
             +  G         G+      + G   SR    ++ G+ E   G     SQ    +   
Sbjct: 1719 GSGLGHSSSH-GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHF 1777

Query: 637  RPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHN-----GEGNGQS---GHSAA 688
                  G+     ++  Q     G  S   ++G  +S  +     G G+GQS   G   +
Sbjct: 1778 CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGS 1837

Query: 689  GPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ-EKGDFTGHGERKGRN- 746
            G G +S      S GS   S     GS   ++ SGF  + +   +   +T HG   G + 
Sbjct: 1838 GSGHSSSYGQHGS-GSGWSSSSGRHGSGSGQS-SGFGHHESSSWQSSGYTQHGSGSGHSS 1895

Query: 747  --EKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLL 804
              E+  S   +  +G  H      S S  +H   +    G  +      Q+    SRG  
Sbjct: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS-PSRGRH 1954

Query: 805  NKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERR 864
                G       +G     SSS  P       +   +  +     QSS +   GS S   
Sbjct: 1955 GSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSS-GLGHRESRSGQSSGYGQHGSSSGHS 2013

Query: 865  SVICDISPLRQIVRDPGAH--SLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLK 922
            S               G H  S G  S+  + G     +    +      G  S ++   
Sbjct: 2014 STHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ-----GSGSGQSPGH 2068

Query: 923  SQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSI-------KHESYRGNASP----GAAT 971
             Q G    +     +   S + + S    H P +        HES  G +S     G+ +
Sbjct: 2069 GQRGSGSRQSPSYGR-HGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGS 2127

Query: 972  HDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPH 1031
              S S YG   SR     R     G R G    S S+Y       + S G  R   G  H
Sbjct: 2128 GHS-SGYGQHGSRSGQSSR-----GERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGH 2181

Query: 1032 ------------HMNPHMTFSERANRSSLHTPF-SPNSETLASAYHANTRAHA-----YG 1073
                        H + H      + RSS   P+ S +  +     H +   H+     +G
Sbjct: 2182 SPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG 2241

Query: 1074 DPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVR 1133
              +    SQ  +     Q    + +  S+G +    +  QH     + S   QQ     +
Sbjct: 2242 SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS---SHGQHGSGSSQSSSYGQQGSGSGQ 2298

Query: 1134 SPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSR 1193
            SP +       +G   G         +G    SS G    G     G    + S W  S 
Sbjct: 2299 SPSRG-----RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 2353

Query: 1194 QTSPAKSSGPPGMSSQ--KRYGPPHETDGHGLAEATQSS--KPGSVMLRLPGQEDH---S 1246
             T     SG      Q   R G     + HG +  + SS  + GS   +  G   H   S
Sbjct: 2354 YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 2413

Query: 1247 SQNPLIMRRR 1256
             Q+P   R R
Sbjct: 2414 GQSPSPSRGR 2423



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 283/1321 (21%), Positives = 410/1321 (31%), Gaps = 175/1321 (13%)

Query: 3    SFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGA 62
            +F ++ S  G   SY     GSS+   +    A   Q+       SGS  S S G     
Sbjct: 1322 TFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSG 1381

Query: 63   AAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQ 122
            +  +++     SG     GF       +  +G        T        S   + +G   
Sbjct: 1382 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG-------CTQHGSGSGHSSSYEQHGSRS 1434

Query: 123  G-SSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQ 181
            G SS G ++GS         QH    G    Q    G    GS Q    +  +      Q
Sbjct: 1435 GQSSRGERHGSSSGSSSSYGQH----GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ 1490

Query: 182  QLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASS 241
                  Y S      + G   S SSH   +    +    ++GY       GQH  SS  S
Sbjct: 1491 SSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGY-------GQHGSSSGHS 1543

Query: 242  SSSSSFPSPQRFSQSGQSYD-GSYNVNAG--SQYEGHNVGSN-AQAYGTQSNYSYQPQSM 297
            S+       Q  S SGQS   G +  ++G  S +  H  GS+ +  YG Q + S Q    
Sbjct: 1544 STHG-----QHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG- 1597

Query: 298  KNFEQAKIPQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQVGQ-- 346
                      G +    +Q P   +H S         QH      ++     +S  GQ  
Sbjct: 1598 ---------HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1648

Query: 347  -YNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPM 405
             Y+Q          + Q+ S  S  S       S S SS+      +G     G G    
Sbjct: 1649 SYSQHGSGSGHSSGYGQHGSR-SGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGS 1707

Query: 406  GSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVAN 465
            GS        P      S +   +SH     G G         +  G SS+       + 
Sbjct: 1708 GSGQ-----SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSG 1762

Query: 466  LPNTV-QHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCS 524
              +   QH   S     Q +       S   D   +S G S    Q  S  ++S   G  
Sbjct: 1763 HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ 1822

Query: 525  SSSEDQG-ERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGA----------------QNE 567
             S   Q   R R  SG   SS     G  S  + SS   G+                Q+ 
Sbjct: 1823 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882

Query: 568  PPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGS 627
                + S +    +          SS G    +         +     R     GQ    
Sbjct: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942

Query: 628  QEDDPAATQRPPSNGGAKETSH---------ASLPQPEPPGGGGSKGNKNGDNNSNHN-- 676
                P+ ++    +G  + +S+         +S   P   G G S G  + ++ S  +  
Sbjct: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002

Query: 677  -GEGNGQSGHSAAGPGFTSRTEPSKSPG-----SLRYSYKDSFGSAVPRNVSGFPQYPTG 730
             G+    SGHS+      S +  S S G     S + S     GS   ++ SG+ +  +G
Sbjct: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQS-SGYGRQGSG 2061

Query: 731  QEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMA-----GSLEGT 785
               G   GHG+R   + + PS       G H     R S S Q   G+      G  E +
Sbjct: 2062 --SGQSPGHGQRGSGSRQSPS------YGRHGSGSGRSSSSGQHGPGLGESSGFGHHESS 2113

Query: 786  TRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKF 845
            +  +   SQ    +         GS       G     SS ++    Q            
Sbjct: 2114 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHG---------- 2163

Query: 846  EIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLS 905
                QSS H   GS S         SP R        HS  H    +  GR+    P  S
Sbjct: 2164 SGSRQSSGHGRQGSGSGH-------SPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYES 2216

Query: 906  QSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNA 965
            +S     G  S+  + +S SG           S  S +   SG  C       +   G+ 
Sbjct: 2217 RS-----GHSSVFGQHESGSGH---------SSAYSQHGSGSGHFC------SQGQHGST 2256

Query: 966  SPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRG 1025
            S  ++T D       Q S             G+ G      S Y         SP R R 
Sbjct: 2257 SGQSSTFDQEGSSTGQSSS-----------HGQHGSGSSQSSSYGQQGSGSGQSPSRGRH 2305

Query: 1026 PGGDPHHMN--PHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQL 1083
              G  H  +   H + S  ++ S  H   S  S        ++ ++  Y    +G     
Sbjct: 2306 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 2365

Query: 1084 HYKR---QMYQQQPEEYKDWSSGSA-------QGVIAAAQHRQEGPRKSPRQQQFLDRVR 1133
             Y++   +  Q    E    SSGS+        G   +  H Q G            R  
Sbjct: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425

Query: 1134 SPLKNDKDGMMYG------PPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQES 1187
            S          YG         G Y   S   +G     S    + G   +HGS     S
Sbjct: 2426 SGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG-QHGSSSGHSS 2484

Query: 1188 CWDLSRQTSPAKSS-GPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHS 1246
                   TS   SS G  G SS +     H   G G ++++   + GS   + PG     
Sbjct: 2485 THGQHGSTSGQSSSCGQHGASSGQ--SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 2542

Query: 1247 S 1247
            S
Sbjct: 2543 S 2543



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 200/926 (21%), Positives = 307/926 (33%), Gaps = 160/926 (17%)

Query: 7    QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGR------- 59
            QSS +G Q S   +     R    S   +   Q+  G+G SS S   GSG G+       
Sbjct: 1815 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1874

Query: 60   ----------------------------------RGAAAAAAAMASETSGHQGYQGFRKE 85
                                              RG    +++ +S + G  G  G R+ 
Sbjct: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHG-SGSRQS 1933

Query: 86   AGDFYYMAGNKDPVTTGTPQPPQRR---PSGPVQSYGP-PQGSSFGNQYG----SEGHVG 137
             G   + +G+       +P P + R    SG   SYGP   GS + +  G      GH  
Sbjct: 1934 LGHGQHGSGSGQ-----SPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSS 1988

Query: 138  QFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQA 197
                + S  G  S Y Q   G  S  S+ + Q  S+  Q     Q      QS      +
Sbjct: 1989 GLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSASGQSSSCGQHGASSGQS-----SS 2041

Query: 198  TGQPASSSSHLQPMQRPSTLPSSAAGYQLRVG------QFGQHYQSSASSSSSSSF-PSP 250
             GQ  S SS      R  +    + G+  R         +G+H   S  SSSS    P  
Sbjct: 2042 HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGL 2101

Query: 251  QRFSQSGQSYDGSYNVNAGSQY---EGHNVG-----------SNAQAYGTQSNYSYQPQS 296
               S  G     S   ++ SQ+    GH+ G           S  + +G+ S  S +   
Sbjct: 2102 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ 2161

Query: 297  MKNFEQAKIPQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQVGQ- 346
              +  +     G Q       P + +H S         QH      ++++ P +S+ G  
Sbjct: 2162 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS 2221

Query: 347  --YNQPEVPVRSPMQFHQNFSP----ISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ 400
              + Q E        + Q+ S      S     ++  QS +     S   Q+  + Q G 
Sbjct: 2222 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS 2281

Query: 401  GSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGF----KGFGLEGVPEKRLTDPGLSS- 455
            GS    S  +      Q SP+     S + H++ +     G G      +  +  G SS 
Sbjct: 2282 GSSQSSSYGQQGSGSGQ-SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG 2340

Query: 456  LSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPM 515
                 +         QH   S   +  ++   R   S + +   +S GSS    Q  S  
Sbjct: 2341 FGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGS 2400

Query: 516  AESLDGGCSSSSEDQG---ERVRQLSGQSTSSD-TTYKGGASEKAGSSPAQGAQNEPPRL 571
             +SL  G   S   Q     R R  SG   SS  + Y  G+   +   P +        L
Sbjct: 2401 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL 2460

Query: 572  NASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDD 631
                +   +++  G      SS G+   +                     GQ   +    
Sbjct: 2461 GHRESRSGQSSGYGQHG---SSSGHSSTH---------------------GQHGSTSGQS 2496

Query: 632  PAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQS-GHSAAGP 690
             +  Q   S+G  + +SH         G G S+ +  G       G G+GQS GH   G 
Sbjct: 2497 SSCGQHGASSG--QSSSHGQ------HGSGSSQSSGYG-----RQGSGSGQSPGHGQRGS 2543

Query: 691  GFTSRTEPS---KSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ-EKGDFTGHGERKGRN 746
            G  SR  PS      GS R S     GS +  + SGF  + +   +   ++ HG   G +
Sbjct: 2544 G--SRQSPSYGRHGSGSGRSSSSGQHGSGLGES-SGFGHHESSSGQSSSYSQHGSGSGHS 2600

Query: 747  EKF---PSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGL 803
              +    S   +  +G  H      S    +H   +    G  R     S + +  SRG 
Sbjct: 2601 SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG---SGSGQSPSRGR 2657

Query: 804  LNKSIGSLLENPHWGPWERKSSSTAP 829
                +G    +   G    +SSS  P
Sbjct: 2658 HGSGLGHSSSHGQHGSGSGRSSSRGP 2683



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 242/1188 (20%), Positives = 379/1188 (31%), Gaps = 165/1188 (13%)

Query: 134  GHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQP 193
            G    +  Q S  G  +      +G    GS   Q     Q      Q      + S   
Sbjct: 167  GQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSG 226

Query: 194  LPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQ------HYQSSASSSSSSSF 247
                  Q  SSS       +  +    ++GY     + GQ      H  SS SSSS    
Sbjct: 227  QSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQH 286

Query: 248  PSPQRFS-----QSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQ 302
             S  R S     Q   S     +V  GS   G    S+   +G+ S+YSY   S  ++E 
Sbjct: 287  GSGSRQSLGHGRQGSGSRQSPSHVRHGS---GSGHSSSHGQHGSGSSYSY---SRGHYES 340

Query: 303  AKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQ 362
                Q +  GQ +    Q    S+H     +++++       GQ+        S  Q   
Sbjct: 341  GS-GQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQ-------GQHGSTSGQASSSGQHGS 392

Query: 363  NFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTP 422
            +    S  S +    +S S  S+      +G     G G    GS               
Sbjct: 393  S----SRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGS--------------- 433

Query: 423  SMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSS-LSALSTQVANLPNTVQHMLLSDALTP 481
               PS   H     GFG        ++  G SS      +   +     QH   S   + 
Sbjct: 434  GQSPSSGQHGT---GFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSG 490

Query: 482  QKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLD---GGCSSSSEDQGERVRQLS 538
              +   R   S + +   +S GSS    Q  S   +SL     G  S       R R  S
Sbjct: 491  HGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHES 550

Query: 539  GQSTSSD---TTYKGGASE-----KAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMP 590
            G   SS      Y  G S      ++GS  + G  ++  R   S    +  +S G     
Sbjct: 551  GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTH 610

Query: 591  LSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQ-----RPPSNG-GA 644
                G+      + G      A +G+    G    GS +      Q     + PS G   
Sbjct: 611  -GQHGSTSGQSSSCG---QHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHG 666

Query: 645  KETSHASLPQPEPPGGG-----GSKGNKNGDNNSNHNGEGNGQ-SGHSAAGPGFTSRTEP 698
             +  H+S       G G     G  G+ +G ++   +  G+GQ SG+S  G G +S +  
Sbjct: 667  SDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSG-SSHSSG 725

Query: 699  SKSPGSL--RYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEV 756
             +  GS   + S  +  GS+   + S + Q+ +G  +   +GHG +   +   PS ++  
Sbjct: 726  YRKHGSRSGQSSRSEQHGSSSGLS-SSYGQHGSGSHQS--SGHGRQGSGSGHSPSRVRHG 782

Query: 757  LQGYH------HHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGS 810
                H      H      S S   ++  +G   G  +      Q    +  G  +    S
Sbjct: 783  SSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQ--GYSQHGSASGHFSS 840

Query: 811  LLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDI 870
              +  H     + SSS   +      + Y        + +S++H   G            
Sbjct: 841  --QGRHGSTSGQSSSSGQHDSSSGQSSSYG-------QHESASHHASG------------ 879

Query: 871  SPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKE 930
               R         S GH    +  G++       S S     G  S   +  S SGQ   
Sbjct: 880  ---RGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGS-----GRSSSSGRHGSGSGQSSG 931

Query: 931  EDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATH----DSLSDYGPQDS--- 983
               + S  Q+S   +      H  S +    R   S  +  H     S S YG   S   
Sbjct: 932  FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSR 991

Query: 984  --------------RPTPMRRVPGRVGGREGMRG--RSPSQYHDFAEKLKMSPGRSRGPG 1027
                           P+P R   G   G+    G  RS S +       +   G S G G
Sbjct: 992  QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLG 1051

Query: 1028 ------GDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNS 1081
                  G       H + S  ++    H   S  S +      ++ ++ ++G   +G + 
Sbjct: 1052 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 1111

Query: 1082 QLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKD 1141
               Y RQ              GS  G       R  G R+SP   +          + + 
Sbjct: 1112 SSGYGRQ--------------GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 1157

Query: 1142 GMMYGPPVG-TYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1200
            G   G   G  +H+ S+ ++        G  +     +HGS+  Q S  +    +S + S
Sbjct: 1158 GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 1217

Query: 1201 S-GPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSS 1247
              G  G  S++  G  H   G G   +    + GS +        H S
Sbjct: 1218 HYGQHGSGSRQSSG--HGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGS 1263



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 77/326 (23%), Positives = 107/326 (32%), Gaps = 39/326 (11%)

Query: 7    QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSG----------------- 49
            QS  HG + S  ++     R    S R +   Q+  G G SSG                 
Sbjct: 2534 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH 2593

Query: 50   --SSGSGSGGGRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPP 107
               SG  SG G+ G+ +  ++         G      + G     +       +G+ Q P
Sbjct: 2594 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSP 2653

Query: 108  QRRPSGPVQSY---------GPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTG 158
             R   G    +         G  + SS G      GH   F    SG G  S Y Q  +G
Sbjct: 2654 SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG 2713

Query: 159  PFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLP 218
              S       Q  S+  Q     Q      QS     + +G   SS           +L 
Sbjct: 2714 --SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLS 2771

Query: 219  SSAAGY-QLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNV 277
                G    +   +GQH   S  SS  S     Q  S SGQ  DG      GS ++G + 
Sbjct: 2772 HGRHGSGSGQSSSYGQHGSGSGQSSGYS-----QHGSGSGQ--DGYSYCKGGSNHDGGSS 2824

Query: 278  GSNAQAY-GTQSNYSYQPQSMKNFEQ 302
            GS   ++  + S Y Y  +    F Q
Sbjct: 2825 GSYFLSFPSSTSPYEYVQEQRCYFYQ 2850



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 70/296 (23%), Positives = 105/296 (35%), Gaps = 28/296 (9%)

Query: 7    QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR---GAA 63
            QSS +G Q S   +  G  +    S +     ++  G+G SS S   GSG G     G  
Sbjct: 2521 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580

Query: 64   AAAAAMASETSGHQGYQGFRKEAGDF-----YYMAGNKDPVTTGTPQPPQRRPSGPVQSY 118
             +++  +S  S H    G     G           G +   ++G+     +  SG  QS 
Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 2640

Query: 119  GPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTG---PFSPGSAQYQQQASSQQ 175
            G  +  S   Q  S G  G      SGLG  S + Q  +G     S G  + +   SS  
Sbjct: 2641 GHGRQGSGSGQSPSRGRHG------SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVF 2694

Query: 176  QQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHY 235
             Q +        Y  H      +G   S   H     + ST     +      GQ   + 
Sbjct: 2695 GQHESGSGHSSAYSQH---GSGSGHFCSQGQHGSTSGQSSTFDQEGSS----TGQSSSYG 2747

Query: 236  QSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYS 291
               + SS SS +   +  + SGQS   S+  +     +  + G +    G  S YS
Sbjct: 2748 HRGSGSSQSSGY--GRHGAGSGQSL--SHGRHGSGSGQSSSYGQHGSGSGQSSGYS 2799


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 274/1284 (21%), Positives = 412/1284 (32%), Gaps = 223/1284 (17%)

Query: 6    EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAA 65
            + +SY+ N+ +YP      +     SPR           GG+ GS  + + G +   +++
Sbjct: 211  QYNSYYPNRSAYPPPAPAYALS---SPR-----------GGTPGSGAAAAAGSKPPPSSS 256

Query: 66   AAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQ--RRPSGPVQSYGPPQG 123
            A+A +S +S  Q  Q F    G     AG   P  T TP   Q    PS      G P G
Sbjct: 257  ASASSSSSSFAQ--QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGG 314

Query: 124  S-SFGNQYGSEGH------------VGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQ 170
              S G Q G  G                  A  +  GG    Q+ +  P SPGS+    Q
Sbjct: 315  DYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQ--QRSHHAPMSPGSSGGGGQ 372

Query: 171  ASSQQQQ-----QQVQQLRQQLYQSHQPLPQATGQPAS-SSSHLQP-----MQRPSTLPS 219
              ++  Q      Q+ ++R Q Y    P  Q  G P+     H  P      Q P   P 
Sbjct: 373  PLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPM 432

Query: 220  SAAG----------YQLRVGQFGQHYQSSASSSSSSSF-----PSPQRFSQSGQSYDGSY 264
            +  G          Y  ++  +GQ   S       + +     P PQ+          S 
Sbjct: 433  TMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQ 492

Query: 265  NVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHP 324
              +A   Y+        Q   +Q  YS QP S    +Q+  P  +QQ   QQ PQ Q   
Sbjct: 493  TPHAQPSYQQQPQSQPPQLQSSQPPYSQQP-SQPPHQQSPAPYPSQQSTTQQHPQSQPPY 551

Query: 325  SQHVMQ--YTNAATKLPLQSQVGQ---YNQPEVPVRSPMQFHQNFSP----ISNPSPAAS 375
            SQ   Q  Y     + P  S + Q   Y QP+        + Q   P    +S  S  + 
Sbjct: 552  SQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQ 611

Query: 376  VVQSPSCSSTPSPLMQTGENLQCGQGSVP-MGSRNRILQLMPQLSPTPSMMPSPNSHAAG 434
               +PS +S+         +LQ    S+P +      L +  + + +P +  S  S + G
Sbjct: 612  ASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQG 671

Query: 435  FKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHML---LSDALTPQKKTSKRPSS 491
             +    +  P    T P L  +   S      P +V       LS A  P  +   RP S
Sbjct: 672  EQSNPAQS-PFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPS 730

Query: 492  ---------SKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSG--- 539
                     S    S     G  Q   Q+    +    G   S  +  G ++    G   
Sbjct: 731  GQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ-YSSPQPGSALSPRQPSGGQIHTGMGSYQ 789

Query: 540  QSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP-GAKDMPLSSDGNPK 598
            Q++      +GG     G  P Q   N  P  N   A      +P GA        G P 
Sbjct: 790  QNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPP 849

Query: 599  VNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLP----- 653
                  G    R +      +P G +  +      +   PP  G  ++T   ++      
Sbjct: 850  YGTLPPG----RMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAA 905

Query: 654  ---QPEPPG-----GGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSL 705
               Q  PPG      GG  G           G   GQ  +S AG     +  P    G++
Sbjct: 906  NSIQNRPPGYPNMNQGGMMG----------TGPPYGQGINSMAGM-INPQGPPYSMGGTM 954

Query: 706  RYSYKDSFGSAVPRNVSGFPQYPTG-----QEKGDFTGHGERKGRNEKFPSLLQEVLQGY 760
                 +S G A    + G              K D T   E K +     +   E +   
Sbjct: 955  A---NNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKL 1011

Query: 761  HH---HPDR-----RYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGSLL 812
            +     P+R     RY   T+E         G T    +  +  +L    +  K IG L 
Sbjct: 1012 YELGGEPERKMWVDRYLAFTEE------KAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLT 1065

Query: 813  ENPHWGPWER--------KSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERR 864
            +      W           SSS A  +K+  +        FE + +     P    +   
Sbjct: 1066 QVNKNKKWRELATNLNVGTSSSAASSLKKQYI---QCLYAFECKIERGEDPPPDIFA--- 1119

Query: 865  SVICDISPLRQIVRDPGAHSLGHM-------SADTRIGRNDRLNPTL------SQSVILP 911
                D    +  ++ P     G M       S  + +     L P        SQ   LP
Sbjct: 1120 --AADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLP 1177

Query: 912  GGLVSMETKLKSQSGQIKEEDFEQSKSQASF--NNKKSGDHCHPPSIKHESYRGNASPGA 969
            G          S+S  +  +D     S ++F   N  + +  + PS+      G  S   
Sbjct: 1178 G---------MSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMS--- 1225

Query: 970  ATHDSLSDYGPQDSRPTPMRRVPGR---VGGREGMRGRSPSQYHDFAEKLKMSPGRSRGP 1026
                    Y P       MR+ PG    +   +G  G     Y            R+ GP
Sbjct: 1226 --------YEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY-----------SRAAGP 1266

Query: 1027 GGDPHHMNP--HMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLH 1084
            G     M P  H  +    +R        P       A   N       +P++G+ S   
Sbjct: 1267 GLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMP---SNPDSGMYSPSR 1323

Query: 1085 YKRQMYQQQPEEYKDWSSG-SAQGVIAAAQHRQEGPRKSPRQQQF---------LDRVRS 1134
            Y  Q  QQQ + +  + +  S QG  + +    +      +QQQ          ++   S
Sbjct: 1324 YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTS 1383

Query: 1135 PLKND--KDGMMY---GPPVGTYH 1153
            P K+     GM     GPPV   H
Sbjct: 1384 PSKSPFLHSGMKMQKAGPPVPASH 1407



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 163/799 (20%), Positives = 263/799 (32%), Gaps = 95/799 (11%)

Query: 39  QNFGGTGGSSGSSGSGSGGG---------RRGAAAAAAAMASETSGHQGYQGFRKEAG-- 87
           Q+   + G  G  G+GSGGG           G A    A+ +  +   G  G     G  
Sbjct: 74  QDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133

Query: 88  -DFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGL 146
              +  A    P   G  QP  R PS    +      + F  Q+G +   G    Q  G 
Sbjct: 134 APPHSAAAALPPPAYGFGQPYGRSPS----AVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189

Query: 147 GGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSS 206
           GG+  Y          G   +Q  +    +             S +     +G  A++ S
Sbjct: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGS 249

Query: 207 HLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQ-----RFSQSGQSYD 261
              P    S   SS++  Q R G  G    S+A   +     +P          S + Y 
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309

Query: 262 G--SYNVNAGSQYEGHNVG---SNAQAYGTQSNYSYQPQSMKNFEQ----AKIPQGTQQG 312
           G    + + G Q  G   G     +Q +G  +  +    +    +Q    A +  G+  G
Sbjct: 310 GYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG 369

Query: 313 QQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVG--QYNQPEVPVRSPMQFH--------- 361
             Q   +  Q PS  + Q      K+  Q   G   Y+Q + P   P Q H         
Sbjct: 370 GGQPLARTPQ-PSSPMDQ----MGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGS 424

Query: 362 ---QNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRN--RILQLMP 416
              Q + P++    A S +   S +    P  Q G +    QG  P  ++      Q  P
Sbjct: 425 QTPQRY-PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQP 483

Query: 417 QLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHML-- 474
             S  P   PS   HA        +  P+ +   P L S     +Q  + P   Q     
Sbjct: 484 PYSQQP---PSQTPHAQP----SYQQQPQSQ--PPQLQSSQPPYSQQPSQPPHQQSPAPY 534

Query: 475 -LSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGER 533
               + T Q   S+ P S  +A S    +   QP     S  A         S +    +
Sbjct: 535 PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQ 594

Query: 534 VRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSS 593
            R    Q  S D+     +S  + +S   G ++    L + P++  +  S    D+P+ +
Sbjct: 595 QRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPD-LSGSIDDLPMGT 653

Query: 594 DGNPKVNEKTVGVIVSREAMTGRVEKPGGQD-----KGSQEDDPAATQRPPSNGGAKE-- 646
           +G       T G+  S+   +   + P          G +   P+    P S   ++   
Sbjct: 654 EGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGP 713

Query: 647 TSHASLP---QPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPG 703
            S A++P    P  P  G S    +   N +   +  G    +   P ++     S  PG
Sbjct: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYS-----SPQPG 768

Query: 704 SLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHH 763
           S   S +   G  +   +  + Q       G +   G + G    +P         Y+  
Sbjct: 769 S-ALSPRQPSGGQIHTGMGSYQQ----NSMGSYGPQGGQYGPQGGYPR-----QPNYNAL 818

Query: 764 PDRRYSRSTQEHQGMAGSL 782
           P+  Y  +     GMAG +
Sbjct: 819 PNANYPSA-----GMAGGI 832



 Score = 32.3 bits (72), Expect = 4.7
 Identities = 66/292 (22%), Positives = 100/292 (34%), Gaps = 54/292 (18%)

Query: 1357 QKITSPNIRRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKR------KG 1410
            Q +TSP+   SA       GGD           SG P+ G      AD+  +        
Sbjct: 297  QLLTSPS---SARGYQGYPGGDY----------SGGPQDGGAGKGPADMASQCWGAAAAA 343

Query: 1411 EVASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQ 1470
              A+     A Q  H     P SS      +    +  +  + +   +  P   T+  SQ
Sbjct: 344  AAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ 403

Query: 1471 KPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVT--ISPKQEGF 1528
            +    QG P G   G     +P      P G   P+  P   +    +    +S  Q+  
Sbjct: 404  Q----QGPPSGPQQGHG---YPGQ----PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQ-I 451

Query: 1529 PPKGYF-PSGKKKGRPIGSVNKQK---KQQQPPPPPPQPPQIPEGSADGEPKPKKQ---- 1580
            PP G   PSG  +       N+Q    +QQQPP     P Q P      + +P+ Q    
Sbjct: 452  PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511

Query: 1581 -----------RQRRERRKPGAQPRKRKTKQAVPIVEP--QEPEIKLKYATQ 1619
                        Q   ++ P   P ++ T Q  P  +P   +P+ +  Y  Q
Sbjct: 512  QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQ 563



 Score = 32.3 bits (72), Expect = 4.7
 Identities = 37/156 (23%), Positives = 59/156 (37%), Gaps = 44/156 (28%)

Query: 1465 TSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPK 1524
            + T  + P + QGR   ++GG +      ++ +PP G                       
Sbjct: 424  SQTPQRYPMTMQGRAQSAMGGLSY-----TQQIPPYG----------------------- 455

Query: 1525 QEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRR 1584
            Q+G  P GY   G++   P  +      QQQ PP   QPP     S     +P  Q+Q  
Sbjct: 456  QQG--PSGY---GQQGQTPYYNQQSPHPQQQQPPYSQQPP-----SQTPHAQPSYQQQ-- 503

Query: 1585 ERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620
                P +QP + ++ Q     +P +P  +   A  P
Sbjct: 504  ----PQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP 535


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 258/1319 (19%), Positives = 425/1319 (32%), Gaps = 193/1319 (14%)

Query: 5    REQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGT-GGSSGS--SGSGSGGGRRG 61
            R   S  G Q+S  ++   SSR       Q  +  + G + GG  GS    S    G  G
Sbjct: 1781 RTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSG 1840

Query: 62   AAAAAAAMASETSGHQGYQGFR---------KEAGDFYYMAGNKDPVTTGTPQPPQRRPS 112
            +  +       +   +G  G R         K++GD    +G++    +      +    
Sbjct: 1841 SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQV 1900

Query: 113  GPVQSYGPP----QGSSFGNQYGSEGHVGQFQAQHSGLGGVSH----YQQDYTGPFSPGS 164
            G  QS GP     QGSS      S+GH  +   + SG    +H    ++Q   G   PGS
Sbjct: 1901 GQGQSSGPRTSRNQGSSVSQDSDSQGH-SEDSERWSGSASRNHLGSAWEQSRDGSRHPGS 1959

Query: 165  AQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGY 224
              ++ +A         +Q   +  +S      + GQ ASS    +          S+AG 
Sbjct: 1960 -HHEDRAGHGHSADSSRQSGTRHTES-----SSRGQAASSHEQAR----------SSAGE 2003

Query: 225  QLRVGQFGQHYQ-SSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQA 283
            +      G H+Q  SA SS  S     Q  S    S    Y+ +  S  EGH+  S+ Q+
Sbjct: 2004 R-----HGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQS 2058

Query: 284  YGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQ----QQQPQQQQHPSQHVMQYTNAATKLP 339
               Q       QS K  E A+   G   G+      Q    +Q  S H     +   +  
Sbjct: 2059 VSAQGKAGPHQQSHK--ESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGR-- 2114

Query: 340  LQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCG 399
               Q   Y+Q +   R         +   +P P+    Q    S     + ++G +    
Sbjct: 2115 ---QGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQG---SHQEQSVDRSGHS---- 2164

Query: 400  QGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSAL 459
                  GS +         S T S   S  S              +K  +  G     + 
Sbjct: 2165 ------GSHH---------SHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSH 2209

Query: 460  STQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESL 519
              + ++  ++ +H L+    +   +TS+   SS   DS  +SEG S+  E+     + + 
Sbjct: 2210 HHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDS--DSEGHSEDSERRSGSASRNH 2267

Query: 520  DGGCSSSSEDQGERVRQ----LSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASP 575
             G     S D     R      +G   S++++ + G      SS  Q A +   +  +S 
Sbjct: 2268 HGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHE-QARSSA 2326

Query: 576  AAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAAT 635
              R  +    + D    S  +  +        V      G         +G  ED    +
Sbjct: 2327 GERHGSHHQQSAD----SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQS 2382

Query: 636  QRPPSNGGAKETSHASLPQPEPPGGGGSKGN--------------------KNGDNNSNH 675
                   G  + SH    +    G  G  G+                      G    +H
Sbjct: 2383 VSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSH 2442

Query: 676  NGEGNGQSGHSAAGPGF-TSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKG 734
            + +    S HS +  G  T    P  S G  + S+ +        + S    + T Q + 
Sbjct: 2443 HKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHH-SHTTSQGRS 2501

Query: 735  DFT-GHG-----ERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRP 788
            D + GH       R+ RN++            HH    R   S     G   S    T  
Sbjct: 2502 DASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSR 2561

Query: 789  NVLVSQTNELASRGLLNKS---IGSLLENPHWGPWER-KSSSTAPEMKQINLTDYPIPRK 844
            N   S + +  S+G    S    GS   N H    E+ +  S  P   Q +   +     
Sbjct: 2562 NWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSAD 2621

Query: 845  FEIEP------------QSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHS-LGHMSAD 891
               +              +S+HE   S +  R          Q   D   HS +GH  A 
Sbjct: 2622 SSRQSGTRHTQTSSGGQAASSHEQARSSAGERH-----GSHHQQSADSSRHSGIGHGQAS 2676

Query: 892  TRIGRNDRLNPTLSQSVILPGGLVSMETKLKS---QSGQIKEEDFEQSKSQASFNNKKSG 948
            + +  +     + SQ+    G     +T+  S   Q+G  ++   E ++ ++   +  SG
Sbjct: 2677 SAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSG 2736

Query: 949  DHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSP-- 1006
               +  S   +S   +   G +T                     GR G R      S   
Sbjct: 2737 SFLYQVSTHEQSESSHGWTGPSTR--------------------GRQGSRHEQAQDSSRH 2776

Query: 1007 SQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHAN 1066
            S   D  + ++  PG SRG                   R   H   S +S   + ++H++
Sbjct: 2777 SASQDGQDTIRGHPGSSRG------------------GRQGYHHEHSVDSSGHSGSHHSH 2818

Query: 1067 TRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIA----------AAQHRQ 1116
            T +    D + G +      R    ++        SGS     +          A Q + 
Sbjct: 2819 TTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQS 2878

Query: 1117 EGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGME 1176
            EG R+S RQ   + +      + +D   +       H  SAQE    L      P    E
Sbjct: 2879 EGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQ---LRDGSRHPRSHQE 2935

Query: 1177 LKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSV 1235
             + G     +S      + +   S G    S ++      E  G    ++  SS+   +
Sbjct: 2936 DRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2994



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 288/1429 (20%), Positives = 471/1429 (32%), Gaps = 214/1429 (14%)

Query: 6    EQSSYHGNQQSYPQEVHGS--------SRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGG 57
            + +S H   +S P E HGS        SR       QA    +  G  GSSGS  S S G
Sbjct: 368  QTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEG 427

Query: 58   GRR--------GAAAAAAAMASETSGHQGYQGFR--KEAGDFYYMAGNKDP--------V 99
                       G   A     S     +G  G R  +     Y ++ ++ P         
Sbjct: 428  HSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGT 487

Query: 100  TTGTPQPPQRRPSGPVQSYGPPQ----------GSSFGNQYGSEGHVGQFQAQHSGLGGV 149
            +TG  Q      +     +   Q          GSS G + GS       ++ HSG    
Sbjct: 488  STGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSG---- 543

Query: 150  SHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQ 209
            SH+    +   S  S       S+ +Q +  +Q       S     +A+ Q A SS H Q
Sbjct: 544  SHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQ-ADSSRHSQ 602

Query: 210  PMQRPSTLPSSAAGYQLRVGQFGQ---HYQSS---ASSSSSSSFPSPQRFSQSGQSYDGS 263
              Q  S+ P ++      V Q      H + S   + S+S +   S Q  S+ G  +  S
Sbjct: 603  VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRS 662

Query: 264  YNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQ------- 316
            ++ +      GH+  S+ ++    +  S   Q+  + EQA+   G + G + Q       
Sbjct: 663  HHEDRAGH--GHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSS 720

Query: 317  --------QPQQQQHPSQHVMQYTNAATKLPLQSQ------VGQYNQPEVPVRSPMQFHQ 362
                    Q       S H     + AT     S+      V  + Q     +S  +  +
Sbjct: 721  RHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESAR 780

Query: 363  NFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTP 422
            + S   +    + + Q  +   + S    TG +    QGS    +R+       Q     
Sbjct: 781  DRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQ-DGQD 839

Query: 423  SMMPSPNSHAAGFKG---------FGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHM 473
            ++   P S   G +G          G  G      T  G S  S   +   +   T ++ 
Sbjct: 840  TIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN- 898

Query: 474  LLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGER 533
                    Q +   R S S+  ++ ++++ S   +               +   + +G R
Sbjct: 899  ------EEQSRDGSRHSGSRHHEASSHADISRHSQ---------------AGQGQSEGSR 937

Query: 534  VRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSS 593
              +  G S S D+  +G + +   S    G+ +   R +A   +R  +  P +     + 
Sbjct: 938  TSRRQGSSVSQDSDSEGHSED---SERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAG 994

Query: 594  DGNPKVNEKTVGVIVSREAMTGRVE-KPGGQDKGSQE---DDPAATQRPPSNGGAKETSH 649
             G+   +        SR++ T   E   GGQ   S E     P           A  + H
Sbjct: 995  HGHSADS--------SRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRH 1046

Query: 650  ASLPQPE------PPGGGGSKGNKNGDNNSNHNGEGNGQ--SGHSAAGPGFTSRTEPSKS 701
            + +P+ +        G  GS G++  D +  H+ E + Q  SGH   GP   S  E    
Sbjct: 1047 SGIPRRQASSAVRDSGHWGSSGSQASD-SEGHSEESDTQSVSGHGQDGPHQQSHQE---- 1101

Query: 702  PGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYH 761
                  S +D  G    R+ S   Q  T ++    + HG  +    +         QG H
Sbjct: 1102 ------SARDWSGGRSGRSGSFIYQVSTHEQSE--SAHGRTRTSTGR--------RQGSH 1145

Query: 762  HHPDRRYSR--STQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGP 819
            H   R  SR  ++QE Q    +  G+ R     S   +   R        S     H   
Sbjct: 1146 HEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDR--------SGHSGSHHSH 1197

Query: 820  WERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRD 879
               +  S A   +  + +     RK +     S H   GS     +   D S   Q+ ++
Sbjct: 1198 TTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRH--SGSRHHEAASWADSSRHSQVGQE 1255

Query: 880  PGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQ 939
              + S       + + ++         S  L G      +  ++  G  +E+  + S+  
Sbjct: 1256 QSSGSRTSRHQGSSVSQDSDSERHSDDSERLSG------SASRNHHGSSREQSRDGSR-H 1308

Query: 940  ASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGRE 999
              F+ +    H H      +S           H   S +G   S     R  PG   G  
Sbjct: 1309 PGFHQEDRASHGHSADSSRQS--------GTHHTESSSHGQAVSSHEQARSSPGERHGSR 1360

Query: 1000 GMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETL 1059
              +    S++     +   S  R  G  G        +T SE  +  S     S + +  
Sbjct: 1361 HQQSADSSRHSGIGHRQASSAVRDSGHRGS---SGSQVTNSEGHSEDSDTQSVSAHGQAG 1417

Query: 1060 ASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDW--SSGSAQGVIAAAQHRQE 1117
                     A      ++G +    Y+   ++Q    +     S+G  QG       R E
Sbjct: 1418 PHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQG------SRHE 1471

Query: 1118 GPRKSPR---QQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRC-LMSSDGLPNK 1173
              R S R    Q   D +R        G   G   G+YH+ S   +G      S   P  
Sbjct: 1472 QARNSSRHSASQDGQDTIRG-----HPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQG 1526

Query: 1174 GMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPP--------HETDGHGLAE 1225
              +  HG    Q      SRQT   + SG     S  R+  P        H   G G + 
Sbjct: 1527 RSDASHG----QSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESA 1582

Query: 1226 ATQSS-KPGSVMLRLPGQEDHSSQNPLIMRRRVRS-FISPIPSKRQSQDVKNSSTEDKGR 1283
             +++S + GS + +    E HS  +        R+ + S     R       S  ED+  
Sbjct: 1583 GSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRAS 1642

Query: 1284 LLHSSKEG-------ADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDS 1325
              HS++         A+ +    A  S  Q   S  +R  S+   S DS
Sbjct: 1643 HGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADS 1691



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 301/1429 (21%), Positives = 487/1429 (34%), Gaps = 225/1429 (15%)

Query: 1    MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 60
            + S  +  S HG  Q+ P          E +   ++   +  G     G  GS S GGR+
Sbjct: 1445 VSSHEQSESTHG--QTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGS-SRGGRQ 1501

Query: 61   GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 120
            G+    +    + SGH GY             +  +    + + Q      SG    +  
Sbjct: 1502 GSYHEQSV---DRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSG 1558

Query: 121  PQGSSFGNQYGSEGH--VGQFQAQHSGLG---GVSHYQQDYTGPFSPGSAQYQQQASSQQ 175
             +      + GS  H  VGQ ++  S      G S  Q   +   S  S +  + AS   
Sbjct: 1559 SRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNH 1618

Query: 176  QQQQVQQLR--QQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRV----- 228
                 +Q R   +  +SHQ    + G  A SS         ++    AA  Q +      
Sbjct: 1619 YGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPG 1678

Query: 229  GQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAY---- 284
             + G  +Q SA SS+ S     Q  S  G S +   + +  S  EGH+  S+ Q+     
Sbjct: 1679 ERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHG 1738

Query: 285  ---------------------GTQSNYSYQPQSMKNFEQAKIPQG-TQQGQQQQQPQQQQ 322
                                 G   ++ YQ  + +  E A    G +  G+Q+ + +Q +
Sbjct: 1739 QAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQAR 1798

Query: 323  HPSQHVMQYTNAAT--KLPLQSQVG-QYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQS 379
              S+H        T    P  S+ G Q +  E  V S    H         S   S V S
Sbjct: 1799 DSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDS--SGHSGSHHSHTTSQERSDV-S 1855

Query: 380  PSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLM------PQLSPTPSMMP--SPNSH 431
               S + S   QT    Q G GS   GSR+             Q+    S  P  S N  
Sbjct: 1856 RGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQG 1915

Query: 432  AAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSS 491
            ++  +    +G  E      G +S + L +      +  +H        P      R   
Sbjct: 1916 SSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRH--------PGSHHEDRAGH 1967

Query: 492  SKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGG 551
               ADS   S G+   E   +   A S +   SS+ E  G   +  S  S+       G 
Sbjct: 1968 GHSADSSRQS-GTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQ 2026

Query: 552  ASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSRE 611
            AS     S  +G        + S A+  E  S  +    +S+ G    ++++      +E
Sbjct: 2027 ASSAVRDSGHRG-------YSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQS-----HKE 2074

Query: 612  AMTGRVEKPGG-------QDKGSQEDDPAATQRPPSNGG--------AKETSHASLPQPE 656
            +  G+  +  G       Q    ++ +    Q  PS GG        A+++S  S  Q  
Sbjct: 2075 SARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEG 2134

Query: 657  PPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTS---RTEPSKSPGSLRYSYKDSF 713
                 G  G   G    +H  +   +SGHS +    T+   R++ S+     R + + ++
Sbjct: 2135 QDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTY 2194

Query: 714  G---SAVPRNVSGFPQYPTG----QEKGDFTGHGERKGRNEKFP---SLLQEV-LQGYHH 762
                S      SG   +         +    G G+  G     P   S+ Q+   +G+  
Sbjct: 2195 DKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSE 2254

Query: 763  HPDRRYSRSTQEHQGMA--GSLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPW 820
              +RR   +++ H G A   S +G+  P    S   + A  G  + +  S     H    
Sbjct: 2255 DSERRSGSASRNHHGSAQEQSRDGSRHPR---SHHEDRAGHG--HSAESSRQSGTHHA-- 2307

Query: 821  ERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDP 880
            E  S   A    +              + +SSA E  GS  ++ +             D 
Sbjct: 2308 ENSSGGQAASSHE--------------QARSSAGERHGSHHQQSA-------------DS 2340

Query: 881  GAHS-LGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKS---QSGQIKEEDFEQS 936
              HS +GH  A + +  +     + SQ+    G     +T+  S   Q+G  ++   E +
Sbjct: 2341 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST 2400

Query: 937  KSQASFNNKKSGDHCHPPSIKHESYRGNASPGAAT-------HDSLSDYGPQDSRPTPMR 989
            + +++  + +SG   +  S   +S   +   G +T       H    D     +      
Sbjct: 2401 RGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQD 2460

Query: 990  RVPGRVGGREGMRGRSPSQYHDFAEKL---------KMSPGRSRGPGGDPHHMNPHMTFS 1040
             + G  G   G  GR  S Y    ++            S GRS     D  H +     +
Sbjct: 2461 TIHGHPGSSSG--GRQGSHYEQLVDRSGHSGSHHSHTTSQGRS-----DASHGHSGSRSA 2513

Query: 1041 ERANRSSLHTPFSPNSETLASAYH-ANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKD 1099
             R  R+   +     S    S +H A++RA + G    G         Q   + P   ++
Sbjct: 2514 SRQTRNDEQS--GDGSRHSGSRHHEASSRADSSGHSQVG---------QGQSEGPRTSRN 2562

Query: 1100 WSSGSAQGVIAAAQHRQEGPRKS---------PRQQQFLDRVRSPLKNDKDGMMYGPPV- 1149
            W S  +Q   +   H ++  R S           Q+Q  D  R P  + +D   +G    
Sbjct: 2563 WGSSFSQDSDSQG-HSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSAD 2621

Query: 1150 -----GTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQ--------TS 1196
                 GT H  ++   G+   S +   +   E +HGS   Q +  D SR         +S
Sbjct: 2622 SSRQSGTRHTQTS-SGGQAASSHEQARSSAGE-RHGSHHQQSA--DSSRHSGIGHGQASS 2677

Query: 1197 PAKSSGPPGMS-SQKRYGPPHETD-------GHGLAEATQSSKPGSVMLRLPGQEDHSSQ 1248
              + SG  G S SQ      H  D        HG A + Q S   S   R      HS  
Sbjct: 2678 AVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGS 2737

Query: 1249 NPLIMRRRVRSFIS---PIPSKRQSQDVKNSSTEDKGRLLHS-SKEGAD 1293
                +    +S  S     PS R  Q  ++   +D  R  HS S++G D
Sbjct: 2738 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR--HSASQDGQD 2784



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 272/1344 (20%), Positives = 428/1344 (31%), Gaps = 220/1344 (16%)

Query: 8    SSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGS-----GSGGGRRGA 62
            SS H   Q     +HG         RQ   ++      G SGS  S     G      G 
Sbjct: 2449 SSRHSTSQEGQDTIHGHPGSSS-GGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGH 2507

Query: 63   AAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQ 122
            + + +A     +  Q   G R      +  +   D  ++G  Q  Q +  GP  S     
Sbjct: 2508 SGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRAD--SSGHSQVGQGQSEGPRTSRN--W 2563

Query: 123  GSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQ 182
            GSSF     S+GH  +   + SG    +H+          GSAQ Q +  S+  +     
Sbjct: 2564 GSSFSQDSDSQGH-SEDSERWSGSASRNHH----------GSAQEQLRDGSRHPR----- 2607

Query: 183  LRQQLYQSHQPLPQATGQPASSS--SHLQPMQRPSTLPSSAAGYQLRVG---QFGQHYQS 237
                   SHQ      G  A SS  S  +  Q  S   ++++  Q R     + G H+Q 
Sbjct: 2608 -------SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ 2660

Query: 238  SASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS- 296
            SA SS  S     Q  S    S    Y+ +  S  EGH+  S+ Q+           QS 
Sbjct: 2661 SADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSH 2720

Query: 297  ---------------------MKNFEQAKIPQG----TQQGQQQQQPQQQQHPSQHVMQY 331
                                 +   EQ++   G    + +G+Q  + +Q Q  S+H    
Sbjct: 2721 QESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQ 2780

Query: 332  TNAATKL--PLQSQVGQ---YNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTP 386
                T    P  S+ G+   +++  V        H + +     S A     S   S + 
Sbjct: 2781 DGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDA-----SRGQSGSR 2835

Query: 387  SPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEK 446
            S    T    Q G GS   GSR+        +S     +   +  +   +  G     + 
Sbjct: 2836 SASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDS 2895

Query: 447  RLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQ 506
                    S     +   N   + Q  L   +  P+     R      ADS   S G+  
Sbjct: 2896 DSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQS-GTRH 2954

Query: 507  PEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQN 566
             +       A S +   SS+ E  G   +Q +  S  S   + G AS     S  +G   
Sbjct: 2955 TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH-GQASSAVRDSGHRG--- 3010

Query: 567  EPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGG---- 622
                 + S A+  E  S  +    +S+ G    ++++      +E+  GR  +  G    
Sbjct: 3011 ----YSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQS-----HQESARGRSGETSGHSGS 3061

Query: 623  ---QDKGSQEDDPAATQRPPSNGG--------AKETSHASLPQPEPPGGGGSKGNKNGDN 671
               Q    ++ + +     PS  G        A+++S  S  Q       G  G+  G  
Sbjct: 3062 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGR 3121

Query: 672  NSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ 731
               H+      SGHS +    T  T   +S  S   S   S  S   RN          +
Sbjct: 3122 QGYHHEHSVDSSGHSGSHHSHT--TSQGRSDASRGQSGSRS-ASRTTRNE---------E 3169

Query: 732  EKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVL 791
            + GD + H   +                  HH    ++  ++  Q + G  EG+ R    
Sbjct: 3170 QSGDSSRHSVSR------------------HHEASTHADISRHSQAVQGQSEGSRRSRRQ 3211

Query: 792  VSQTNELASRGLLNKSIGSLLENPHW-GPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQ 850
             S  ++ +       S G   ++  W G   R    +  E  +        PR    +  
Sbjct: 3212 GSSVSQDSD------SEGHSEDSERWSGSASRNHRGSVQEQSRHGSRH---PRSHHEDRA 3262

Query: 851  SSAHEPGGSLSERRSVICDISPLRQIVRDPG-----AHSLGHMSADTRIGRNDRLNPTLS 905
               H    S           S  R      G     +H     S   R G   + +   S
Sbjct: 3263 GHGHSADRSRQ---------SGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSS 3313

Query: 906  QSVILPGGLVSMETKLKSQSGQI------KEEDFEQSKSQASFNNKKSGDH--CHPPSIK 957
            +   +P G  S   +     G         E   E+S +Q+   + ++G H   H  S +
Sbjct: 3314 RHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESAR 3373

Query: 958  HESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLK 1017
              S   +   G+  +  +S +   +S     R   GR  G    + R  S++    E   
Sbjct: 3374 DRSGGRSGRSGSFLYQ-VSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQD 3432

Query: 1018 MSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNA 1077
               G    PG            S R  R   H   S +    + ++H++T +    D + 
Sbjct: 3433 TIRGH---PG------------SSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASR 3477

Query: 1078 GLNSQLHYKRQMYQQQPE---EYKDWSSGSAQGVIA-------AAQHRQEGPRKSPRQQQ 1127
            G +      RQ    +         WS        A       + Q +  GPR S  Q  
Sbjct: 3478 GQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGS 3537

Query: 1128 FLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQES 1187
             + +      + +D   +       H  SAQE  R        P    E + G     ES
Sbjct: 3538 SVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSR---DGSRHPTSHHEDRAGHGHSAES 3594

Query: 1188 CWDLSRQTS---PAKSSGPPGMSSQ--------KRYGPPHETD---------GHGLAEAT 1227
                SRQ+       SSG    SS         +R+G  H+           GHG A + 
Sbjct: 3595 ----SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSA 3650

Query: 1228 --QSSKPGSVMLRLPGQEDHSSQN 1249
               S   GS   +    E HS  +
Sbjct: 3651 VRDSGHRGSSGSQASDSEGHSEDS 3674



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 251/1298 (19%), Positives = 415/1298 (31%), Gaps = 170/1298 (13%)

Query: 6    EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAA 65
            + SS H   Q     + G         + +   Q+   +G S       +  GR  A+  
Sbjct: 2123 QDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRG 2182

Query: 66   AAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP----P 121
             +   S ++  + Y   ++++GD    +G+     +      +    G  QS GP    P
Sbjct: 2183 QSG--SRSASRKTYD--KEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRP 2238

Query: 122  QGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQ 181
            +GSS      SEGH  +   + SG    +H+          GSAQ Q +  S+  +   +
Sbjct: 2239 RGSSVSQDSDSEGH-SEDSERRSGSASRNHH----------GSAQEQSRDGSRHPRSHHE 2287

Query: 182  QLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASS 241
              R     S +   Q+    A +SS  Q         SSA        + G H+Q SA S
Sbjct: 2288 D-RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGE------RHGSHHQQSADS 2340

Query: 242  SSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAY----------------- 284
            S  S     Q  S    S     + +  S  EGH+  S+ Q+                  
Sbjct: 2341 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST 2400

Query: 285  --------GTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPS------QHVMQ 330
                    G   ++ YQ  + +  E A    GT  G +Q    +Q   S      Q    
Sbjct: 2401 RGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQD 2460

Query: 331  YTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLM 390
              +         + G + +  V        H + +     S A     S   S + S   
Sbjct: 2461 TIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDA-----SHGHSGSRSASR 2515

Query: 391  QTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTD 450
            QT  + Q G GS   GSR+         S    +    +      + +G     +     
Sbjct: 2516 QTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQG 2575

Query: 451  PGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQ 510
                S     +   N   + Q  L   +  P+     R      ADS   S G+   +  
Sbjct: 2576 HSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQS-GTRHTQTS 2634

Query: 511  LKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPR 570
                 A S +   SS+ E  G   +Q +  S  S   + G AS     S  +G       
Sbjct: 2635 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH-GQASSAVRDSGHRG------- 2686

Query: 571  LNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGG-------Q 623
             + S A+  E  S  +    +S+ G    ++++      +E+  GR  +  G       Q
Sbjct: 2687 YSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQS-----HQESARGRSGETSGHSGSFLYQ 2741

Query: 624  DKGSQEDDPAATQRPPSNGG--------AKETSHASLPQPEPPGGGGSKGNKNGDNNSNH 675
                ++ + +     PS  G        A+++S  S  Q       G  G+  G     H
Sbjct: 2742 VSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYH 2801

Query: 676  NGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGD 735
            +      SGHS +    T  T   +S  S   S   S  S   RN          ++ GD
Sbjct: 2802 HEHSVDSSGHSGSHHSHT--TSQGRSDASRGQSGSRS-ASRTTRNE---------EQSGD 2849

Query: 736  FTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQT 795
             + H                   G  HH    ++  ++  Q + G  EG+ R     S  
Sbjct: 2850 GSRHS------------------GSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSV 2891

Query: 796  NELASRGLLNKSIGSLLENPHW-GPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAH 854
            ++ +       S G   ++  W G   R    +A E  +        PR  + +     H
Sbjct: 2892 SQDSD------SEGHSEDSERWSGSASRNHHGSAQEQLRDGSRH---PRSHQEDRAGHGH 2942

Query: 855  EPGGSLSERRSVICDISPLRQIVRDPG-----AHSLGHMSADTRIGRNDRLNPTLSQSVI 909
                S           S  R      G     +H     SA  R G + + +   S+   
Sbjct: 2943 SADSSRQ---------SGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG 2993

Query: 910  LPGGLVSMETKLKSQSGQI------KEEDFEQSKSQASFNNKKSGDH--CHPPSIKHESY 961
            +  G  S   +     G         E   E S +Q+   + ++G H   H  S +  S 
Sbjct: 2994 IGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSG 3053

Query: 962  RGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGR----EGMRGRSPSQYHDFAEKLK 1017
              +   G+  +   +    + S         GR G R    +     S SQY    + ++
Sbjct: 3054 ETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQ--DTIR 3111

Query: 1018 MSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNA 1077
              PG SRG     HH +   +     +  S H+  +    + AS   + +R+ +    N 
Sbjct: 3112 GHPGSSRGGRQGYHHEH---SVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNE 3168

Query: 1078 GLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLK 1137
              +            +   + D S  S      A Q + EG R+S RQ   + +      
Sbjct: 3169 EQSGDSSRHSVSRHHEASTHADISRHSQ-----AVQGQSEGSRRSRRQGSSVSQDSDSEG 3223

Query: 1138 NDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSP 1197
            + +D   +       H  S QE  R        P    E + G     +       + + 
Sbjct: 3224 HSEDSERWSGSASRNHRGSVQEQSR---HGSRHPRSHHEDRAGHGHSADRSRQSGTRHAE 3280

Query: 1198 AKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSV 1235
              S G    S ++    P E  G    ++  SS+   +
Sbjct: 3281 TSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGI 3318



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 261/1254 (20%), Positives = 425/1254 (33%), Gaps = 195/1254 (15%)

Query: 3    SFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGA 62
            S   ++S H +   + Q V G S     S RQ         + G S  S   SG   R  
Sbjct: 2856 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 2915

Query: 63   AAAAAAMASETSGH-QGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPP 121
              +A     + S H + +Q  R  AG  +    ++   T  T    Q    G   S    
Sbjct: 2916 HGSAQEQLRDGSRHPRSHQEDR--AGHGHSADSSRQSGTRHT----QTSSGGQAASSHEQ 2969

Query: 122  QGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQ----------QDYTGPFSPGSAQYQQQA 171
              SS G ++GS        ++HSG+G   H Q          + Y+G  +  +  + + +
Sbjct: 2970 ARSSAGERHGSHHQQSADSSRHSGIG---HGQASSAVRDSGHRGYSGSQASDNEGHSEDS 3026

Query: 172  SSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQP-MQRPSTLPSSAA-----GYQ 225
             +Q      Q    Q  QSHQ    A G+   +S H    + + ST   S +     G  
Sbjct: 3027 DTQSVSAHGQAGSHQ--QSHQ--ESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS 3082

Query: 226  LRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYG 285
             R  Q  +H Q+  SS  S+S    Q    + + + GS        +  H+V S+  +  
Sbjct: 3083 TRGRQGSRHEQAQDSSRHSAS----QYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGS 3138

Query: 286  TQSNYSYQPQSMKNFEQ--AKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQ 343
              S+ + Q +S  +  Q  ++    T + ++Q     +   S+H    T+A      Q+ 
Sbjct: 3139 HHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAV 3198

Query: 344  VGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQ-SPSCSSTPSPLMQTGENLQCGQGS 402
             G   Q E   RS  Q              +SV Q S S   +      +G   +  +GS
Sbjct: 3199 QG---QSEGSRRSRRQ-------------GSSVSQDSDSEGHSEDSERWSGSASRNHRGS 3242

Query: 403  VPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQ 462
            V   SR+                  P SH     G G       R +    +  S+   Q
Sbjct: 3243 VQEQSRHG--------------SRHPRSHHEDRAGHG-HSADRSRQSGTRHAETSS-GGQ 3286

Query: 463  VANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGG 522
             A+     +        +P ++   R   S  ADS   S  S  P  Q  S + +S   G
Sbjct: 3287 AASSHEQARS-------SPGERHGSRHQQS--ADS---SRHSGIPRGQASSAVRDSRHWG 3334

Query: 523  CSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEAT 582
             S S     E      G S  SDT    G  +   + P Q +  E               
Sbjct: 3335 SSGSQASDSE------GHSEESDTQSVSGHGQ---AGPHQQSHQE--------------- 3370

Query: 583  SPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNG 642
               A+D      G        V      E+  GR     G+ +GS  +    + R  ++ 
Sbjct: 3371 --SARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ 3428

Query: 643  GAKETSHASLPQPEPPGGGGS-------KGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSR 695
              ++T     P     G  GS       +   +G ++S+   +G   +    +G    SR
Sbjct: 3429 EGQDTIRGH-PGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASR 3487

Query: 696  --TEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLL 753
                  +S    R+S+     ++   + S   Q   GQ  G  T   +    ++   S  
Sbjct: 3488 QTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDS-- 3545

Query: 754  QEVLQGYHHHPDRRYSRSTQEHQGMA--GSLEGTTRPNVLVSQTNELASRGLLNKSIGSL 811
                QG+    +R    +++ H+G A   S +G+  P    S   + A  G  + +  S 
Sbjct: 3546 ----QGHSEDSERWSGSASRNHRGSAQEQSRDGSRHP---TSHHEDRAGHG--HSAESSR 3596

Query: 812  LENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDIS 871
                H    E  S   A    +              + +SSA E  GS  ++ +      
Sbjct: 3597 QSGTHHA--ENSSGGQAASSHE--------------QARSSAGERHGSHHQQSA------ 3634

Query: 872  PLRQIVRDPGAHS-LGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKS---QSGQ 927
                   D   HS +GH  A + +  +     + SQ+    G     +T+  S   Q+G 
Sbjct: 3635 -------DSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGP 3687

Query: 928  IKEEDFEQSKSQASFNNKKSGDHCHPPSI--KHESYRGNASPG-----AATHDSLSDYGP 980
             ++   E ++ +++  + +SG   +  S   + ES  G A P       + H+   D   
Sbjct: 3688 HQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSR 3747

Query: 981  QDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFS 1040
              +       + G  G R G R  S   YH+       S  RS   G   HH   H T  
Sbjct: 3748 HSASQEGQDTIRGHPGSRRGGRQGS---YHE------QSVDRSGHSGS--HH--SHTTSQ 3794

Query: 1041 ERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDW 1100
             R++ S   +     S    +   +   +   G  +   ++Q    R     Q E     
Sbjct: 3795 GRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSR 3854

Query: 1101 SSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVR--SPLKNDKDGMMYGPPVGTYHDPSAQ 1158
             S      ++     +  P  S R+ +   R    S  +  +DG  +    G+ H  +A 
Sbjct: 3855 RSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRH---PGSSHRDTAS 3911

Query: 1159 EAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRY 1212
                  + SD    K  E  H S   Q+S +      S  +S G P  SS   Y
Sbjct: 3912 HVQSSPVQSDSSTAK--EHGHFSSLSQDSAYH-----SGIQSRGSPHSSSSYHY 3958



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 321/1675 (19%), Positives = 556/1675 (33%), Gaps = 209/1675 (12%)

Query: 5    REQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGT-GGSSGS--SGSGSGGGRRG 61
            R  +S  G Q S+ ++   SSR       Q  +  + G + GG  GS    S +  G  G
Sbjct: 484  RTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSG 543

Query: 62   AAAAAAAMASETSGHQGYQGFR---------KEAGDFYYMAGNKDPVTTGTPQPPQRRPS 112
            +  +       +    G  G R         +++GD    +G++    +      +    
Sbjct: 544  SHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQV 603

Query: 113  GPVQSYGPP----QGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQ 168
            G  QS GP     QGSS      S+GH  +   + SG    +H+          GSAQ Q
Sbjct: 604  GQGQSSGPRTSRNQGSSVSQDSDSQGH-SEDSERWSGSASRNHH----------GSAQEQ 652

Query: 169  QQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSS----HLQPMQRPSTLPSSAAGY 224
             +  S+  +   +      + +       T    +SSS          R S      + +
Sbjct: 653  SRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRH 712

Query: 225  QLRVGQFGQHYQSSASSSSSSSFPSPQRFSQS-------GQSYDGSYNVNAGSQYEGHNV 277
            QL+     +H  +    +SS+   S  R S         G S D      +G    GH+ 
Sbjct: 713  QLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQ 772

Query: 278  GSNAQAYGTQS--------NYSYQPQSMKNFEQAK----IPQGTQQGQQQQQPQQQQH-- 323
             S+ ++   +S        ++ YQ  + K  E +        G +QG   +Q +      
Sbjct: 773  QSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHS 832

Query: 324  PSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCS 383
             SQ              + + G +++  V        H + +     S A     S   S
Sbjct: 833  ASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA-----SRGQS 887

Query: 384  STPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLS--PTPSMMPSPNSHAAGFKGFGLE 441
             + S    T    Q   GS   GSR+        +S         S  S  +  +G  + 
Sbjct: 888  GSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVS 947

Query: 442  GVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNS 501
               +           S  +++  N   + Q      +  P+     R      ADS   S
Sbjct: 948  QDSDSEGHSEDSERWSGSASR--NHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQS 1005

Query: 502  EGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSS------------DTTYK 549
             G+   E       A S +   SS  E  G R +Q +  S  S            D+ + 
Sbjct: 1006 -GTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHW 1064

Query: 550  GGASEKAGSSPAQGAQNEPPRLNA--SPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVI 607
            G +  +A  S     +++   ++        +++    A+D      G        V   
Sbjct: 1065 GSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTH 1124

Query: 608  VSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNK 667
               E+  GR     G+ +GS  +    + R  ++   ++T  A              G++
Sbjct: 1125 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAH------------PGSR 1172

Query: 668  NGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQY 727
             G    +H+ +   +SGHS +    T+    S +          S G +  R+ S   Q 
Sbjct: 1173 RGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA----------SHGQSGSRSAS--RQT 1220

Query: 728  PTGQEKGDFTGH-GERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTT 786
               ++ GD + H G R      +    +    G       R SR    HQG + S +  +
Sbjct: 1221 RKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSR----HQGSSVSQDSDS 1276

Query: 787  RPNVLVSQTNELASRGLLNKSIGSLLE-------NPHWGPWERKSSSTAPEMKQINLTDY 839
              +   S  +E  S        GS  E       +P +   +R S   + +  + + T +
Sbjct: 1277 ERH---SDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHH 1333

Query: 840  PIPRKFEIEPQSSAHEPGGSLSE--RRSVICDISPLRQIVRDPGAHS-LGHMSADTRIGR 896
                      +SS+H    S  E  R S         Q   D   HS +GH  A + +  
Sbjct: 1334 ---------TESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRD 1384

Query: 897  NDRLNPTLSQSVILPGGLVSMETKLKS---QSGQIKEEDFEQSKSQASFNNKKSGDHCHP 953
            +     + SQ     G     +T+  S   Q+G  ++   E ++ Q+  ++ +S    + 
Sbjct: 1385 SGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQ 1444

Query: 954  PSI--KHESYRGNASPGAA---------THDSLSDYGPQDSRPTPMRRVPGRV-GGREG- 1000
             S   + ES  G  +P              +S      QD + T +R  PG   GGR+G 
Sbjct: 1445 VSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDT-IRGHPGSSRGGRQGS 1503

Query: 1001 -----MRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPN 1055
                 +     S YH      +     S G  G P   +      E++   S H+     
Sbjct: 1504 YHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSG-PRSASRQTRNEEQSGDGSRHS----G 1558

Query: 1056 SETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHR 1115
            S     +  A +  H+         S+   ++     Q  + +  S  S +   +A+++ 
Sbjct: 1559 SRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNH 1618

Query: 1116 QEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPV------GTYHDPSAQEAGRCLMSSDG 1169
                R+  R        R+P  + +D   +G         GT H  +   +G    SS  
Sbjct: 1619 YGSAREQSRHGS-----RNPRSHQEDRASHGHSAESSRQSGTRH--AETSSGGQAASSQE 1671

Query: 1170 LPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQS 1229
                    +HGS+  Q +       T   + S   G S  +       +D  G +E + +
Sbjct: 1672 QARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDT 1731

Query: 1230 SKPGSVMLRLPGQEDH--SSQNPLIMRR-RVRSFISPIPSKRQSQDVKNSSTEDKGRLLH 1286
                +     P Q+ H  S++     R  R  SF+  + +  QS+     +    G    
Sbjct: 1732 QSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQR 1791

Query: 1287 SSKEGADKAFNSYAHLSHSQDIKSIP-----KRDSSKDLPSPDSRNCPA---VTLTSPAK 1338
            S  E A  +    A       I+  P      R  S    S DS           TS  +
Sbjct: 1792 SRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQER 1851

Query: 1339 TKILPPRKG-RGLKLEAIVQKITSPNIRRSAS-SNSAEAGGDTVTLDDILSLKSGPP--- 1393
            + +   + G R +  +   +K +    R S S  + A +  D+     +   +S  P   
Sbjct: 1852 SDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTS 1911

Query: 1394 -EGGSVAVQDA-------DIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRG----SV 1441
               GS   QD+       D E+  G  + + +  A ++       P S  E R     S 
Sbjct: 1912 RNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSA 1971

Query: 1442 DDKVKTET-HAETVTAG---------KEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIF 1491
            D   ++ T H E+ + G         +   G    +  Q   ++  R  G   G A    
Sbjct: 1972 DSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAV 2031

Query: 1492 PDSKNVPPVGILAPEANPKAEEKENDTVT----ISPKQEGFPPKGYFPSGKKKGR 1542
             DS +    G  A ++   +E+ +  +V+      P Q+         SG+  GR
Sbjct: 2032 RDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGR 2086



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 180/873 (20%), Positives = 302/873 (34%), Gaps = 162/873 (18%)

Query: 481  PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540
            P+     R S    ADS   S G+   E   +   A S +   SS  E  G   +Q S  
Sbjct: 336  PRSHDEDRASHGHSADSSRQS-GTRHAETSSRGQTASSHEQARSSPGERHGSGHQQ-SAD 393

Query: 541  STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600
            S+    T +G AS        +G+       + S A+  E  S  +    +S  G   + 
Sbjct: 394  SSRHSATGRGQASSAVSDRGHRGS-------SGSQASDSEGHSENSDTQSVSGHGKAGLR 446

Query: 601  EKTVGVIVSREAMTGRVEKPGGQDKGS-------QEDDPAATQRPPSNGG--------AK 645
            +++      +E+  GR  +  G+   S       ++ D A  +   S GG        A+
Sbjct: 447  QQS-----HQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQAR 501

Query: 646  ETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTS---RTEPSKSP 702
            ++S  S  Q       G  G+  G    +H+ +   +SGHS +    T+   R++ S   
Sbjct: 502  DSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQ 561

Query: 703  GSLRYSYK---------DSFGSAVPRNVSGFPQYPTGQ--EKGDFTGHGERKGRNEKFPS 751
               R + +         D    +  R+     Q  + +  + G     G R  RN+    
Sbjct: 562  SGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSV 621

Query: 752  LLQEVLQGYHHHPDRRYSRSTQEHQGMA--GSLEGTTRPNVLVSQTNELASRGLLNKSIG 809
                  QG+    +R    +++ H G A   S +G+  P    S   + A  G       
Sbjct: 622  SQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPR---SHHEDRAGHG------- 671

Query: 810  SLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICD 869
                  H     RKS +   +    N +        E + +SSA E  GS  + +S    
Sbjct: 672  ------HSADSSRKSGTRHTQ----NSSSGQAASSHE-QARSSAGERHGSRHQLQSA--- 717

Query: 870  ISPLRQIVRDPGAHS-LGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKS---QS 925
                     D   HS  GH  A + +  +     + SQ+    G     +T+  S   Q+
Sbjct: 718  ---------DSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQA 768

Query: 926  GQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRP 985
            G  ++   E ++ ++   +++SG   +  S   +S   +   G +T      +  Q    
Sbjct: 769  GHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQ---- 824

Query: 986  TPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANR 1045
                        R+  R  S SQ  D  + ++  PG SR      HH        E++  
Sbjct: 825  -----------ARDNSR-HSASQ--DGQDTIRGHPGSSRRGRQGSHH--------EQSVD 862

Query: 1046 SSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSA 1105
             S H          + ++H++T +    D + G +      R    ++        SGS 
Sbjct: 863  RSGH----------SGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSR 912

Query: 1106 QGVIA----------AAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDP 1155
                +          A Q + EG R S RQ   + +      + +D   +       H  
Sbjct: 913  HHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRG 972

Query: 1156 SAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPP 1215
            SAQE  R                HGS+  +    D +     A SS        ++ G P
Sbjct: 973  SAQEQSR----------------HGSRHPRSHHEDRAGHGHSADSS--------RQSGTP 1008

Query: 1216 H-ETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVK 1274
            H ET   G A ++      S     PG E H S++    +    S  S IP ++ S  V+
Sbjct: 1009 HAETSSGGQAASSHEQARSS-----PG-ERHGSRH---QQSADSSRHSGIPRRQASSAVR 1059

Query: 1275 NSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQD 1307
            +S          S  EG  +  ++ +   H QD
Sbjct: 1060 DSGHWGSSGSQASDSEGHSEESDTQSVSGHGQD 1092



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 272/1430 (19%), Positives = 458/1430 (32%), Gaps = 183/1430 (12%)

Query: 3    SFREQSSYHGN-----QQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGG 57
            S  E  + HG+     +QS  +    SSR +  S  + Q   + G   GS     S    
Sbjct: 1959 SHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHE-QARSSAGERHGSHHQLQSADSS 2017

Query: 58   GRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQS 117
               G     A+ A   SGH+GY G   +A D    + + D     T     +  +GP Q 
Sbjct: 2018 RHSGIGHGQASSAVRDSGHRGYSG--SQASDSEGHSEDSD-----TQSVSAQGKAGPHQQ 2070

Query: 118  YGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYT-GPFSPGSAQYQQQASSQQQ 176
                + S+ G    S G  G F  Q S     +H Q + T G  +P +   Q     Q Q
Sbjct: 2071 --SHKESARGQSGESSGRSGSFLYQVS-----THEQSESTHGQSAPSTGGRQGSHYDQAQ 2123

Query: 177  ---QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQ 233
               +    Q  Q   + H P P   G+  S     Q + R     S  +    +      
Sbjct: 2124 DSSRHSASQEGQDTIRGH-PGPSRGGRQGSHQE--QSVDRSGHSGSHHSHTTSQGRSDAS 2180

Query: 234  HYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEG--HNVGSNAQAYGTQ---- 287
              QS + S+S  ++   Q  S  G  + GS++  A S  +   H++    Q+ G +    
Sbjct: 2181 RGQSGSRSASRKTYDKEQ--SGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRP 2238

Query: 288  --SNYSYQPQSMKNFEQAKIPQGTQQ-----GQQQQQPQQQQHPSQHVMQYTNAATKLPL 340
              S+ S    S  + E ++   G+         Q+Q     +HP  H             
Sbjct: 2239 RGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAES 2298

Query: 341  QSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ 400
              Q G ++            H+     +     +   QS   S           +   G 
Sbjct: 2299 SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS----------RHSGIGH 2348

Query: 401  GSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALS 460
            G      R+   +       + S   S +S        G  G  ++   +      +  S
Sbjct: 2349 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 2408

Query: 461  TQVANLPNTVQHMLLSDALTPQKKTS---KRPSSSKKADSCTNSEGSSQPEEQLKSPMAE 517
             +  +    V     S++   +  TS   ++ S  K+A   +    S + ++ +      
Sbjct: 2409 GRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGS 2468

Query: 518  SLDGGCSSSSEDQGERVRQLSGQSTS--SDTTYKGGASEKAGSSPAQGAQNEPPRLNAS- 574
            S  G   S  E   +R    SG S S  S TT +G +    G S ++ A  +      S 
Sbjct: 2469 SSGGRQGSHYEQLVDR----SGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSG 2524

Query: 575  PAAREEATSPGAKDMPLSSDGNPKVNE-KTVGVIVSREAMTGRVEKPGGQDKGSQEDDPA 633
              +R   +          S G+ +V + ++ G   SR    G         +G  ED   
Sbjct: 2525 DGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRN--WGSSFSQDSDSQGHSEDSER 2582

Query: 634  ATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFT 693
                   +G A    H S  +    G    + ++       H+ + + QSG         
Sbjct: 2583 ------WSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSG--------- 2627

Query: 694  SRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKG--RNEKFPS 751
            +R   + S G    S++ +  SA  R+ S   Q      +    GHG+     R+     
Sbjct: 2628 TRHTQTSSGGQAASSHEQARSSAGERHGS-HHQQSADSSRHSGIGHGQASSAVRDSGHRG 2686

Query: 752  LLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNV--LVSQTNELASRGLLNKSIG 809
                       H +   ++S   H G AGS + + + +      +T+  +   L   S  
Sbjct: 2687 YSGSQASDNEGHSEDSDTQSVSAH-GQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTH 2745

Query: 810  SLLENPH-W-GPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVI 867
               E+ H W GP  R    +  E  Q    D       +    +    PG S   R+   
Sbjct: 2746 EQSESSHGWTGPSTRGRQGSRHEQAQ----DSSRHSASQDGQDTIRGHPGSSRGGRQGYH 2801

Query: 868  CDISPLRQIVRDPGAHSLGHMSADTRIGRND----------------------------- 898
             + S       D   HS  H S  T  GR+D                             
Sbjct: 2802 HEHSV------DSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSG 2855

Query: 899  ------RLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCH 952
                    +  +S+      G      + + Q   + ++   +  S+ S     S    H
Sbjct: 2856 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 2915

Query: 953  PPSIKHESYRGNASPGAATHDSLS-DYGPQDSRPTPMRRVPGRVGGR--------EGMRG 1003
              S + +   G+  P +   D     +    SR +  R      GG+            G
Sbjct: 2916 HGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAG 2975

Query: 1004 RSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAY 1063
                 +H  +       G   G        + H  +S   +++S +   S +S+T + + 
Sbjct: 2976 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYS--GSQASDNEGHSEDSDTQSVSA 3033

Query: 1064 HANTRAH--AYGDPNAGLNSQL--HYKRQMYQ----QQPEEYKDWSSGSAQGVIAAAQHR 1115
            H    +H  ++ +   G + +   H    +YQ    +Q E    W+  S +G   +   +
Sbjct: 3034 HGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQ 3093

Query: 1116 QEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGM 1175
             +   +    Q   D +R        G   G   G +H+ S   +G          ++G 
Sbjct: 3094 AQDSSRHSASQYGQDTIRG-----HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQG- 3147

Query: 1176 ELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPHETDGHG----LAEATQSSK 1231
              +  + + Q      SR T   + SG     S  R+   HE   H      ++A Q   
Sbjct: 3148 --RSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRH---HEASTHADISRHSQAVQGQS 3202

Query: 1232 PGSVMLRLPG--------QEDHSSQNPLIMRRRVRSFISPIPSK-RQSQDVKNSSTEDKG 1282
             GS   R  G         E HS  +        R+    +  + R       S  ED+ 
Sbjct: 3203 EGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRA 3262

Query: 1283 RLLHSSKEG-------ADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDS 1325
               HS+          A+ +    A  SH Q   S  +R  S+   S DS
Sbjct: 3263 GHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS 3312



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 90/437 (20%), Positives = 144/437 (32%), Gaps = 66/437 (15%)

Query: 3    SFREQS---SYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGR 59
            S +EQS   S H       +  HG S              + GG   SS      S G R
Sbjct: 3566 SAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGER 3625

Query: 60   RGA--------------AAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQ 105
             G+                  A+ A   SGH+G  G   +A D    + + D     T  
Sbjct: 3626 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSG--SQASDSEGHSEDSD-----TQS 3678

Query: 106  PPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQD----YTGPFS 161
                  +GP Q     Q S+ G   G  G  G F  Q S     +H Q +      GP +
Sbjct: 3679 VSAHGQAGPHQQ--SHQESTRGRSAGRSGRSGSFLYQVS-----THEQSESAHGRAGPST 3731

Query: 162  PGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSA 221
             G    + + +    +    Q  Q   + H   P +       S H Q + R     S  
Sbjct: 3732 GGRQGSRHEQARDSSRHSASQEGQDTIRGH---PGSRRGGRQGSYHEQSVDRSGHSGSHH 3788

Query: 222  AGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEG--HNVGS 279
            +    +      H QS + S+S  +    Q  S  G  + GS +  A +Q +   H+   
Sbjct: 3789 SHTTSQGRSDASHGQSGSRSASRETRNEEQ--SGDGSRHSGSRHHEASTQADSSRHSQSG 3846

Query: 280  NAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQ-----------GQQQQQPQQQQHPSQHV 328
              ++ G++ +        ++ +    P+ +++             ++Q     +HP    
Sbjct: 3847 QGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSH 3906

Query: 329  MQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSC--SSTP 386
                +     P+QS             S  + H +FS +S  S   S +QS     SS+ 
Sbjct: 3907 RDTASHVQSSPVQSD-----------SSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSS 3955

Query: 387  SPLMQTGENLQCGQGSV 403
                  G   Q GQ  +
Sbjct: 3956 YHYQSEGTERQKGQSGL 3972


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
            sapiens]
          Length = 2231

 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 174/692 (25%), Positives = 238/692 (34%), Gaps = 144/692 (20%)

Query: 9    SYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGG--GRRGAAAAA 66
            SY G   SYP+    S+     S  Q+Q        GG   ++G G G   G + AAA+ 
Sbjct: 374  SYGG---SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430

Query: 67   AAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQ----------PPQRRPSGPVQ 116
            A  A++   H                    DP+    PQ           PQ+    P  
Sbjct: 431  AWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG 490

Query: 117  SYGPP---------QGSSFGNQYGSEGHVGQFQAQHSGLGGVSHY----QQDYTG----- 158
            SYGPP         QG + G   G +    Q   Q+ G  GVS Y    QQ Y       
Sbjct: 491  SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQY-GQQGVSGYCQQGQQPYYSQQPQP 549

Query: 159  PFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLP 218
            P  P  AQY    S Q+ Q Q Q + Q+ Y +    P A G+P     +L   +RPS+LP
Sbjct: 550  PHLPPQAQYLPSQSQQRYQPQ-QDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLP 608

Query: 219  SSAAGYQ-LRVGQFGQHYQS-SASSSSSS----SFPSPQRFSQSGQSYDGSYNVNAGSQY 272
              +     L  G       + SAS S+SS    S P+   FS     +  S         
Sbjct: 609  DLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSP 668

Query: 273  EGHNVGSNA------------------QAYGTQSNYSYQP---QSMKNFEQA------KI 305
             G  VGSN                   Q  G+QS  S  P   QS    E+       + 
Sbjct: 669  VGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRN 728

Query: 306  PQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQVG---QYNQPEVP 353
            PQ  Q G QQ  P    HPS             Q  ++ T  P  SQ G    Y++P   
Sbjct: 729  PQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY 788

Query: 354  VRSPMQFHQNFSP--------------ISNPSPAASVVQSPSC------------SSTPS 387
               P   +    P               S P  A  + + PS             S TPS
Sbjct: 789  SGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPS 848

Query: 388  PLMQTGENLQCGQG-SVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGV--P 444
                 G + Q G G   PM + NR  Q     +   +   S  S    F G    G+   
Sbjct: 849  ---SPGMSQQGGPGMGPPMPTVNRKAQ-EAAAAVMQAAANSAQSRQGSFPGMNQSGLMAS 904

Query: 445  EKRLTDPGLSSLSALSTQV-------ANLPNTVQHMLLSDALTPQK-----------KTS 486
                + P  +S S ++TQ        A + ++   + L+D ++P +           K  
Sbjct: 905  SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEE 964

Query: 487  KRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDT 546
              P    K+    +S+G SQP      P+   +    +S S   G+        S SS  
Sbjct: 965  GTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGD-----ESDSISSPG 1019

Query: 547  TYKGGASEKAGSSPAQGAQ--------NEPPR 570
              K  +S K+ SS   G +        NEP R
Sbjct: 1020 WPKTPSSPKSSSSTTTGEKITKVYELGNEPER 1051



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 139/598 (23%), Positives = 200/598 (33%), Gaps = 109/598 (18%)

Query: 42  GGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGHQGYQGF------------------- 82
           GG+GG  G  G+G+GG   GA AAAAA A+  +G  G  G+                   
Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319

Query: 83  ------------------RKEAGDFYYMAGNKDPVTTGTPQPPQ--RRPSGPVQSYGPPQ 122
                                AG F   AG     +  TP   Q    PS  ++SYG   
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379

Query: 123 GSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQ 182
              + +         Q Q+Q +  G  +  QQ   G    G     Q A++       QQ
Sbjct: 380 -PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG-MGLGKDMGAQYAAASPAWAAAQQ 437

Query: 183 LRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSS 242
                 +SH  +   T  P    S   PM  P  +      Y +      Q  QSS    
Sbjct: 438 ------RSHPAMSPGTPGPTMGRSQGSPMD-PMVMKRPQL-YGMGSNPHSQPQQSSPYPG 489

Query: 243 SSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQ 302
            S   P PQR+    Q    +    AG QY    +      YG Q    Y        +Q
Sbjct: 490 GSYGPPGPQRYPIGIQG--RTPGAMAGMQYPQQQM---PPQYGQQGVSGY-------CQQ 537

Query: 303 AKIPQGTQQGQQQQQPQQQQH-PSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFH 361
            + P  +QQ Q    P Q Q+ PSQ   +Y          SQ G   + + P+      H
Sbjct: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD----MSQEGYGTRSQPPLAPGKPNH 593

Query: 362 QNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSV-PMGSRNRILQ--LMPQL 418
           ++ + I    P++    S S    P+    T  +     GS    G ++   Q    P  
Sbjct: 594 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 653

Query: 419 SPTPSMMP-SPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLP-----NTVQH 472
           SP  S +P  P+    G        V   +     +S  S   +Q+   P      +  H
Sbjct: 654 SPHLSSIPGGPSPSPVG------SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 707

Query: 473 MLLSDALTPQKK-----TSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSS 527
             LS +  PQ++     T + P  ++     T    S  P     SP  + +  G SS  
Sbjct: 708 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP-----SPGGQ-MHAGISSF- 760

Query: 528 EDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPG 585
                       Q ++S  TY    S+       QG  + PP  +  P+A      PG
Sbjct: 761 ------------QQSNSSGTYGPQMSQYG----PQGNYSRPPAYSGVPSASYSGPGPG 802



 Score = 38.5 bits (88), Expect = 0.065
 Identities = 221/1109 (19%), Positives = 358/1109 (32%), Gaps = 169/1109 (15%)

Query: 302  QAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFH 361
            Q ++ Q  QQ QQQQQ QQQQ   QH +   N+     L    G   QP   +  P    
Sbjct: 49   QQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNS-----LGGAGGGAPQPGPDMEQPQHGG 103

Query: 362  QNFSPISNPS--PAASVVQSPSCSSTPSPLM---QTGENLQCGQGSVPMGSRNRILQLMP 416
               S     +  P   ++  P       P M     G     G G+  +G++   +  +P
Sbjct: 104  AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGA--LGTQQPPV-AVP 160

Query: 417  QLSPTPSMMPSPNSH------AAGFKG------FGLEGVPEKRLTDPGLSSLSALSTQVA 464
                 P+ +P  N++      A+G  G      F   G  +     PG+  + + S   A
Sbjct: 161  GGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQ----SPGMGMMHSASAAAA 216

Query: 465  NLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCS 524
              P ++  +  S    P  + +  P  S+         G                 GG  
Sbjct: 217  GAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG----------------GGGG 260

Query: 525  SSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP 584
             S    G       G    +       A+  AG     G            + R++    
Sbjct: 261  GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--- 317

Query: 585  GAKDMPLSSDGNPKVNEKTVGVIVSR-EAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGG 643
            G   M     G   +++   G      +   G+ + P G      +   + +    S GG
Sbjct: 318  GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGG 377

Query: 644  A-KETSHASLPQPEP--PGGGGSKGNKNGDNNSNHNGEGNGQ---SGHSAAGPGFTS--- 694
            +  E S  S P P P  P    +             G G G+   + ++AA P + +   
Sbjct: 378  SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ 437

Query: 695  RTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQ-YPTG-------QEKGDFTGHGERKGRN 746
            R+ P+ SPG+   +   S GS +   V   PQ Y  G       Q+   + G        
Sbjct: 438  RSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497

Query: 747  EKFPSLLQ----EVLQGYHHHPDRRYSRSTQE------HQGMAGSLEGTTRPNVLVSQTN 796
            +++P  +Q      + G  +   +   +  Q+       QG         +P  L  Q  
Sbjct: 498  QRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ 557

Query: 797  ELASRGLLNKSIGSLLENPHWGPWERKSSSTA-PEMKQINLTDYPIPRKFEIEPQSSAHE 855
             L S+          +    +G   +   +   P  + +NL     P        S    
Sbjct: 558  YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617

Query: 856  PGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGG-- 913
            P G+ +   S +                S G  S   +   +   +P LS    +PGG  
Sbjct: 618  PTGTEATLSSAVS---------ASGSTSSQGDQSNPAQSPFSPHASPHLSS---IPGGPS 665

Query: 914  ---LVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAA 970
               + S     +S+SG I       S+               PP  + ES         +
Sbjct: 666  PSPVGSPVGSNQSRSGPISPASIPGSQMPP-----------QPPGSQSES---------S 705

Query: 971  THDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDP 1030
            +H +LS         +PM +  G + G +  R    +QY        MSP  S  PGG  
Sbjct: 706  SHPALSQ--------SPMPQERGFMAGTQ--RNPQMAQYGPQQTGPSMSPHPS--PGG-- 751

Query: 1031 HHMNPHMTFSERANRSSLHTP----FSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYK 1086
              M+  ++  +++N S  + P    + P         ++   + +Y  P  G+   +   
Sbjct: 752  -QMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMG--ISAN 808

Query: 1087 RQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRV-RSPLKNDKDGMMY 1145
             QM+ Q P +          G +   +    G +  P           SP  + + G   
Sbjct: 809  NQMHGQGPSQ--------PCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860

Query: 1146 GPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPG 1205
            GPP+ T  +  AQEA   +M +    N     +     + +S   L   +SP        
Sbjct: 861  GPPMPTV-NRKAQEAAAAVMQA--AANSAQSRQGSFPGMNQS--GLMASSSPYSQPMNNS 915

Query: 1206 MSSQKRYGPPHETDGHGLAEATQSSKPGSVML---RLPGQEDHSSQNPLIMRRRVRSFIS 1262
             S      PP     + +A A  +S   SV L     PG+    S+ PL ++   +   +
Sbjct: 916  SSLMNTQAPP-----YSMAPAMVNSSAASVGLADMMSPGE----SKLPLPLKADGKEEGT 966

Query: 1263 PIPSKRQSQDVKN---SSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKS--IPKRDSS 1317
            P P  +      +   S     G L   S      A  S  H   S  I S   PK  SS
Sbjct: 967  PQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSS 1026

Query: 1318 KDLPSPDSRNCPAVTLTSPAKTKILPPRK 1346
               P   S       +T   +    P RK
Sbjct: 1027 ---PKSSSSTTTGEKITKVYELGNEPERK 1052



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 34/124 (27%), Positives = 46/124 (37%), Gaps = 26/124 (20%)

Query: 166 QYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
           Q+QQQ   QQQQQQ QQ +Q    ++  L  A G        ++  Q      S+A G  
Sbjct: 54  QFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGG-- 111

Query: 226 LRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVN--AGSQYEGHNVGSNAQA 283
                              +  P P   S+ G   D    +   AG +YE   +G    A
Sbjct: 112 ------------------QADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLG----A 149

Query: 284 YGTQ 287
            GTQ
Sbjct: 150 LGTQ 153



 Score = 35.8 bits (81), Expect = 0.42
 Identities = 58/257 (22%), Positives = 85/257 (33%), Gaps = 22/257 (8%)

Query: 118  YGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFS-PGSAQYQQQASSQQQ 176
            YGPP     G+ Y  + +  Q Q  ++  GG       Y+GP   P   QY    S ++ 
Sbjct: 1362 YGPPAKRHEGDMYNMQ-YSSQQQEMYNQYGG------SYSGPDRRPIQGQYPYPYSRERM 1414

Query: 177  QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRP-STLPSSAAGYQLRVGQFG--Q 233
            Q   Q       Q+H   PQ  G P  SSS   P Q   +        YQ R G  G  Q
Sbjct: 1415 QGPGQ------IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQ 1468

Query: 234  HYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQ 293
                   + +       QR +   Q      +V+    Y   +          Q +Y   
Sbjct: 1469 APPYPGMNRTDDMMVPDQRINHESQ---WPSHVSQRQPYMSSSASMQPITRPPQPSYQTP 1525

Query: 294  PQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVP 353
            P    +  +A  P   Q+  + +     + P    M+       +P     G   QP  P
Sbjct: 1526 PSLPNHISRAPSPASFQRSLENRM-SPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP-P 1583

Query: 354  VRSPMQFHQNFSPISNP 370
            +R  + F       S P
Sbjct: 1584 IRREITFPPGSVEASQP 1600



 Score = 33.1 bits (74), Expect = 2.7
 Identities = 62/239 (25%), Positives = 85/239 (35%), Gaps = 40/239 (16%)

Query: 6   EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAA 65
           E SS+    QS   +  G     + +P+ AQ       TG S     S  G    G ++ 
Sbjct: 703 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQ--QTGPSMSPHPSPGGQMHAGISSF 760

Query: 66  AAAMASETSGHQGYQGFRKEAGDFYYMAGN--KDPVTTGTPQPPQRRPSGPVQSYGPPQG 123
             + +S T G Q  Q         Y   GN  + P  +G P       SGP    GP  G
Sbjct: 761 QQSNSSGTYGPQMSQ---------YGPQGNYSRPPAYSGVPSASY---SGP----GPGMG 804

Query: 124 SSFGNQYGSEGHVGQFQAQHSG-LGGVSHYQQDYTG------PFSPGSAQY--------- 167
            S  NQ   +G      A   G +       + + G      P SPG +Q          
Sbjct: 805 ISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPM 864

Query: 168 -QQQASSQQQQQQVQQLRQQLYQSHQ---PLPQATGQPASSSSHLQPMQRPSTLPSSAA 222
                 +Q+    V Q      QS Q   P    +G  ASSS + QPM   S+L ++ A
Sbjct: 865 PTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQA 923


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
            sapiens]
          Length = 2178

 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 200/858 (23%), Positives = 285/858 (33%), Gaps = 175/858 (20%)

Query: 9    SYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGG--GRRGAAAAA 66
            SY G   SYP+    S+     S  Q+Q        GG   ++G G G   G + AAA+ 
Sbjct: 374  SYGG---SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430

Query: 67   AAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQ----------PPQRRPSGPVQ 116
            A  A++   H                    DP+    PQ           PQ+    P  
Sbjct: 431  AWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG 490

Query: 117  SYGPP---------QGSSFGNQYGSEGHVGQFQAQHSGLGGVS---------HYQQDYTG 158
            SYGPP         QG + G   G +    Q   Q+ G  GVS         +Y Q    
Sbjct: 491  SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQY-GQQGVSGYCQQGQQPYYSQQPQP 549

Query: 159  PFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLP 218
            P  P  AQY   + SQQ+ Q  Q + Q+ Y +    P A G+P     +L   +RPS+LP
Sbjct: 550  PHLPPQAQY-LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLP 608

Query: 219  S-SAAGYQLRVG-----QFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQY 272
              S +   L  G             S SS    S P+   FS     +  S         
Sbjct: 609  DLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSP 668

Query: 273  EGHNVGSN------------------AQAYGTQSNYSYQP---QSMKNFEQA------KI 305
             G  VGSN                   Q  G+QS  S  P   QS    E+       + 
Sbjct: 669  VGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRN 728

Query: 306  PQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQV---GQYNQPEVP 353
            PQ  Q G QQ  P    HPS             Q  ++ T  P  SQ    G Y++P   
Sbjct: 729  PQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY 788

Query: 354  VRSPMQFHQNFSP--------------ISNPSPAASVVQSPSC------------SSTPS 387
               P   +    P               S P  A  + + PS             S TPS
Sbjct: 789  SGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPS 848

Query: 388  PLMQTGENLQCGQG-SVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGV--P 444
                 G + Q G G   PM + NR  Q     +   +   S  S    F G    G+   
Sbjct: 849  ---SPGMSQQGGPGMGPPMPTVNRKAQ-EAAAAVMQAAANSAQSRQGSFPGMNQSGLMAS 904

Query: 445  EKRLTDPGLSSLSALSTQV-------ANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADS 497
                + P  +S S ++TQ        A + ++   + L+D ++P +     P    KAD 
Sbjct: 905  SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLP---LKADG 961

Query: 498  CTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSD--------TTYK 549
                EG+ QPE + K           SSSS   GE++ ++       +         T+ 
Sbjct: 962  --KEEGTPQPESKSKK----------SSSSTTTGEKITKVYELGNEPERKLWVDRYLTFM 1009

Query: 550  GGASEKAGSSPAQGAQ--------------NEPPRLNASPAAREEATSPGAKDMPLSSDG 595
                    S PA G +                  ++N +   RE AT+    ++  SS  
Sbjct: 1010 EERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATN---LNVGTSSSA 1066

Query: 596  NPKVNEKTVGVIVSREAMTGRVEKPGGQ--DKGSQEDDPAATQRPPSNGGAKETSHASLP 653
               + ++ +  + + E    R E+P  +    G  +  P      P+N G       SL 
Sbjct: 1067 ASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSG-------SLQ 1119

Query: 654  QPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSF 713
             P+ P   GS        +       +   G      G  S T     P      + D  
Sbjct: 1120 GPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDP------FSDVS 1173

Query: 714  GSAVPRNVSGFPQYPTGQ 731
             S+ P+  S  P  P  Q
Sbjct: 1174 DSSFPKRNSMTPNAPYQQ 1191



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 139/598 (23%), Positives = 200/598 (33%), Gaps = 109/598 (18%)

Query: 42  GGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGHQGYQGF------------------- 82
           GG+GG  G  G+G+GG   GA AAAAA A+  +G  G  G+                   
Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319

Query: 83  ------------------RKEAGDFYYMAGNKDPVTTGTPQPPQ--RRPSGPVQSYGPPQ 122
                                AG F   AG     +  TP   Q    PS  ++SYG   
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379

Query: 123 GSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQ 182
              + +         Q Q+Q +  G  +  QQ   G    G     Q A++       QQ
Sbjct: 380 -PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG-MGLGKDMGAQYAAASPAWAAAQQ 437

Query: 183 LRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSS 242
                 +SH  +   T  P    S   PM  P  +      Y +      Q  QSS    
Sbjct: 438 ------RSHPAMSPGTPGPTMGRSQGSPMD-PMVMKRPQL-YGMGSNPHSQPQQSSPYPG 489

Query: 243 SSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQ 302
            S   P PQR+    Q    +    AG QY    +      YG Q    Y        +Q
Sbjct: 490 GSYGPPGPQRYPIGIQG--RTPGAMAGMQYPQQQM---PPQYGQQGVSGY-------CQQ 537

Query: 303 AKIPQGTQQGQQQQQPQQQQH-PSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFH 361
            + P  +QQ Q    P Q Q+ PSQ   +Y          SQ G   + + P+      H
Sbjct: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD----MSQEGYGTRSQPPLAPGKPNH 593

Query: 362 QNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSV-PMGSRNRILQ--LMPQL 418
           ++ + I    P++    S S    P+    T  +     GS    G ++   Q    P  
Sbjct: 594 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 653

Query: 419 SPTPSMMP-SPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLP-----NTVQH 472
           SP  S +P  P+    G        V   +     +S  S   +Q+   P      +  H
Sbjct: 654 SPHLSSIPGGPSPSPVG------SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 707

Query: 473 MLLSDALTPQKK-----TSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSS 527
             LS +  PQ++     T + P  ++     T    S  P     SP  + +  G SS  
Sbjct: 708 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP-----SPGGQ-MHAGISSF- 760

Query: 528 EDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPG 585
                       Q ++S  TY    S+       QG  + PP  +  P+A      PG
Sbjct: 761 ------------QQSNSSGTYGPQMSQYG----PQGNYSRPPAYSGVPSASYSGPGPG 802



 Score = 40.4 bits (93), Expect = 0.017
 Identities = 203/1039 (19%), Positives = 342/1039 (32%), Gaps = 161/1039 (15%)

Query: 302  QAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFH 361
            Q ++ Q  QQ QQQQQ QQQQ   QH +   N+     L    G   QP   +  P    
Sbjct: 49   QQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNS-----LGGAGGGAPQPGPDMEQPQHGG 103

Query: 362  QNFSPISNPS--PAASVVQSPSCSSTPSPLM---QTGENLQCGQGSVPMGSRNRILQLMP 416
               S     +  P   ++  P       P M     G     G G+  +G++   +  +P
Sbjct: 104  AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGA--LGTQQPPV-AVP 160

Query: 417  QLSPTPSMMPSPNSH------AAGFKG------FGLEGVPEKRLTDPGLSSLSALSTQVA 464
                 P+ +P  N++      A+G  G      F   G  +     PG+  + + S   A
Sbjct: 161  GGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQ----SPGMGMMHSASAAAA 216

Query: 465  NLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCS 524
              P ++  +  S    P  + +  P  S+         G                 GG  
Sbjct: 217  GAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG----------------GGGG 260

Query: 525  SSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP 584
             S    G       G    +       A+  AG     G            + R++    
Sbjct: 261  GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--- 317

Query: 585  GAKDMPLSSDGNPKVNEKTVGVIVSR-EAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGG 643
            G   M     G   +++   G      +   G+ + P G      +   + +    S GG
Sbjct: 318  GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGG 377

Query: 644  A-KETSHASLPQPEP--PGGGGSKGNKNGDNNSNHNGEGNGQ---SGHSAAGPGFTS--- 694
            +  E S  S P P P  P    +             G G G+   + ++AA P + +   
Sbjct: 378  SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ 437

Query: 695  RTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQ-YPTG-------QEKGDFTGHGERKGRN 746
            R+ P+ SPG+   +   S GS +   V   PQ Y  G       Q+   + G        
Sbjct: 438  RSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497

Query: 747  EKFPSLLQ----EVLQGYHHHPDRRYSRSTQE------HQGMAGSLEGTTRPNVLVSQTN 796
            +++P  +Q      + G  +   +   +  Q+       QG         +P  L  Q  
Sbjct: 498  QRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ 557

Query: 797  ELASRGLLNKSIGSLLENPHWGPWERKSSSTA-PEMKQINLTDYPIPRKFEIEPQSSAHE 855
             L S+          +    +G   +   +   P  + +NL     P        S    
Sbjct: 558  YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617

Query: 856  PGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGG-- 913
            P G+ +   S +                S G  S   +   +   +P LS    +PGG  
Sbjct: 618  PTGTEATLSSAVS---------ASGSTSSQGDQSNPAQSPFSPHASPHLSS---IPGGPS 665

Query: 914  ---LVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAA 970
               + S     +S+SG I       S+               PP  + ES         +
Sbjct: 666  PSPVGSPVGSNQSRSGPISPASIPGSQMPP-----------QPPGSQSES---------S 705

Query: 971  THDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDP 1030
            +H +LS         +PM +  G + G +  R    +QY        MSP  S  PGG  
Sbjct: 706  SHPALSQ--------SPMPQERGFMAGTQ--RNPQMAQYGPQQTGPSMSPHPS--PGG-- 751

Query: 1031 HHMNPHMTFSERANRSSLHTP----FSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYK 1086
              M+  ++  +++N S  + P    + P         ++   + +Y  P  G+   +   
Sbjct: 752  -QMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMG--ISAN 808

Query: 1087 RQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRV-RSPLKNDKDGMMY 1145
             QM+ Q P +          G +   +    G +  P           SP  + + G   
Sbjct: 809  NQMHGQGPSQ--------PCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860

Query: 1146 GPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPG 1205
            GPP+ T  +  AQEA   +M +    N     +     + +S   L   +SP        
Sbjct: 861  GPPMPTV-NRKAQEAAAAVMQA--AANSAQSRQGSFPGMNQS--GLMASSSPYSQPMNNS 915

Query: 1206 MSSQKRYGPPHETDGHGLAEATQSSKPGSVML---RLPGQEDHSSQNPLIMRRRVRSFIS 1262
             S      PP     + +A A  +S   SV L     PG+    S+ PL ++   +   +
Sbjct: 916  SSLMNTQAPP-----YSMAPAMVNSSAASVGLADMMSPGE----SKLPLPLKADGKEEGT 966

Query: 1263 PIPSKRQSQDVKNSSTEDK 1281
            P P  +  +   +++T +K
Sbjct: 967  PQPESKSKKSSSSTTTGEK 985



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 37/140 (26%), Positives = 50/140 (35%), Gaps = 20/140 (14%)

Query: 150 SHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQ 209
           +H+   +        A  QQ    QQQQQQ QQ +QQ  Q   P+        +     Q
Sbjct: 32  AHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQ 91

Query: 210 PMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVN-- 267
           P            G  +   Q G    S+A   +    P P   S+ G   D    +   
Sbjct: 92  P------------GPDMEQPQHGGAKDSAAGGQADP--PGPPLLSKPGDEDDAPPKMGEP 137

Query: 268 AGSQYEGHNVGSNAQAYGTQ 287
           AG +YE   +G    A GTQ
Sbjct: 138 AGGRYEHPGLG----ALGTQ 153



 Score = 35.8 bits (81), Expect = 0.42
 Identities = 58/257 (22%), Positives = 85/257 (33%), Gaps = 22/257 (8%)

Query: 118  YGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFS-PGSAQYQQQASSQQQ 176
            YGPP     G+ Y  + +  Q Q  ++  GG       Y+GP   P   QY    S ++ 
Sbjct: 1309 YGPPAKRHEGDMYNMQ-YSSQQQEMYNQYGG------SYSGPDRRPIQGQYPYPYSRERM 1361

Query: 177  QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRP-STLPSSAAGYQLRVGQFG--Q 233
            Q   Q       Q+H   PQ  G P  SSS   P Q   +        YQ R G  G  Q
Sbjct: 1362 QGPGQ------IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQ 1415

Query: 234  HYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQ 293
                   + +       QR +   Q      +V+    Y   +          Q +Y   
Sbjct: 1416 APPYPGMNRTDDMMVPDQRINHESQ---WPSHVSQRQPYMSSSASMQPITRPPQPSYQTP 1472

Query: 294  PQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVP 353
            P    +  +A  P   Q+  + +     + P    M+       +P     G   QP  P
Sbjct: 1473 PSLPNHISRAPSPASFQRSLENRM-SPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP-P 1530

Query: 354  VRSPMQFHQNFSPISNP 370
            +R  + F       S P
Sbjct: 1531 IRREITFPPGSVEASQP 1547



 Score = 33.1 bits (74), Expect = 2.7
 Identities = 62/239 (25%), Positives = 85/239 (35%), Gaps = 40/239 (16%)

Query: 6   EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAA 65
           E SS+    QS   +  G     + +P+ AQ       TG S     S  G    G ++ 
Sbjct: 703 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQ--QTGPSMSPHPSPGGQMHAGISSF 760

Query: 66  AAAMASETSGHQGYQGFRKEAGDFYYMAGN--KDPVTTGTPQPPQRRPSGPVQSYGPPQG 123
             + +S T G Q  Q         Y   GN  + P  +G P       SGP    GP  G
Sbjct: 761 QQSNSSGTYGPQMSQ---------YGPQGNYSRPPAYSGVPSASY---SGP----GPGMG 804

Query: 124 SSFGNQYGSEGHVGQFQAQHSG-LGGVSHYQQDYTG------PFSPGSAQY--------- 167
            S  NQ   +G      A   G +       + + G      P SPG +Q          
Sbjct: 805 ISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPM 864

Query: 168 -QQQASSQQQQQQVQQLRQQLYQSHQ---PLPQATGQPASSSSHLQPMQRPSTLPSSAA 222
                 +Q+    V Q      QS Q   P    +G  ASSS + QPM   S+L ++ A
Sbjct: 865 PTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQA 923


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 191/857 (22%), Positives = 283/857 (33%), Gaps = 89/857 (10%)

Query: 7    QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTG-GSSGSSGSGSGGGRRGAAAA 65
            Q      Q SY Q   GSS+   +    ++    FG  G GSS S+G G  G   G +A 
Sbjct: 760  QHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAG 819

Query: 66   AAAMAS-----------ETSGHQ---GYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRP 111
                 S           E+  HQ   G  G        Y   G+    T+G  Q   R  
Sbjct: 820  FGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQ--HRSS 877

Query: 112  SGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGG-VSHYQQDYTGPFSPGSAQ---Y 167
            SG    +G   GS  G   G   H G    Q+SG G   S   Q   G    GS+Q   Y
Sbjct: 878  SGQYSGFGQ-HGSGSGQSSGFGQH-GTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGY 935

Query: 168  QQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLR 227
             Q  SS  Q     Q R    QS        GQ  S S       +  +    ++G+   
Sbjct: 936  GQHGSSSGQTFGFGQHRSGSGQS-----SGFGQHGSGSGQSSGFGQHESGSGKSSGFGQH 990

Query: 228  VGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEG---HNVGSN-AQA 283
              +  Q       S SS S    Q  S SGQ+     + ++  QY G   H  GS+ +  
Sbjct: 991  ESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSG 1050

Query: 284  YGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVM---QYTNAATKLPL 340
            +G     S Q      +E     + +  GQ      Q     QH     Q +      P 
Sbjct: 1051 FGQHGTGSGQSSGFGQYESRS--RQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPG 1108

Query: 341  QSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ 400
              Q   + Q          F Q+ S     S  A        SS       + ++  CGQ
Sbjct: 1109 SGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQ 1168

Query: 401  ---GSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLE-------GVPEKRLTD 450
               GS P  S  + +      S +   + S +  + GF  +G         G  E +  +
Sbjct: 1169 HESGSGPTTSFGQHVSGSDNFSSSGQHI-SDSGQSTGFGQYGSGSGQSTGLGQGESQQVE 1227

Query: 451  PGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQ 510
             G +      T      NT +H       + Q  T  R +  +++    NS+  S+   +
Sbjct: 1228 SGSTVHGRQETTHGQTINTTRHSQSGQGQSTQ--TGSRVTRRRRSSQSENSD--SEVHSK 1283

Query: 511  LKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSS--DTTYKGGASEKAGSSPAQGAQNEP 568
            +    +E +     S     G  VR+  G +     DTT  G +    G S   G++   
Sbjct: 1284 VSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGH--GQSTQTGSRTSG 1341

Query: 569  PRLNASPAAREEATSPGAKDMPLS-----SDGNPKVNEKTVGVIVSREAMTGRVEKPGGQ 623
             +  +   A +     G    P S     S    +  E    V    E   G+  +  G 
Sbjct: 1342 RQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGH 1401

Query: 624  DKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGG-----------GSKGNKNGDNN 672
                      +TQR     G + + H+     E   GG           G  G+++G++ 
Sbjct: 1402 GHSGHGQ---STQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESG 1458

Query: 673  SN---HNGEGNGQSGHSAAGPGF---TSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQ 726
            S     +G  +GQ+G +     +    S    S + G     + +S  S V    SG   
Sbjct: 1459 STVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVH---SGGSH 1515

Query: 727  YPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGS-LEGT 785
              +G   G     G + G +E        +  G       R+S S  E     GS   G 
Sbjct: 1516 THSGHTHGQ---SGSQHGESESIIHDRHRITHG-QTGDTTRHSYSGHEQTTQTGSRTTGR 1571

Query: 786  TRPNVLVSQTNELASRG 802
             R +   S  +E+ S G
Sbjct: 1572 QRTSHSESTDSEVHSGG 1588



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 178/768 (23%), Positives = 258/768 (33%), Gaps = 121/768 (15%)

Query: 7    QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAA 66
            QSS +G   S   +  G  + E  S + +   Q+  G+G SSG    GSG G+       
Sbjct: 702  QSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQH 761

Query: 67   AAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQGSSF 126
             + + ++S  Q   G  + +G  Y   G++   T+G  Q      SG  QS G  Q  S 
Sbjct: 762  ESRSGQSSYGQHSSGSSQSSG--YGQHGSRQ--TSGFGQ----HGSGSSQSTGFGQYGSG 813

Query: 127  GNQYGSEGHVGQFQAQHSGLG-GVSHYQQDYTGPFSPGSAQ---YQQQASSQQQQQQVQQ 182
              Q    G  G    Q SG G   S   Q   G    GS+Q   Y Q  SS  Q     Q
Sbjct: 814  SGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQ 873

Query: 183  LRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGY-----QLRVGQFGQHYQS 237
             R    Q         GQ  S S       +  T     +G+     +     +GQH   
Sbjct: 874  HRSSSGQY-----SGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSG 928

Query: 238  SA--------SSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEG---HNVGSNA----- 281
            S+         SSS  +F   Q  S SGQS     + +   Q  G   H  GS       
Sbjct: 929  SSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFG 988

Query: 282  --QAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLP 339
              ++  +QSNY  Q  S  +        G+  GQ     Q +    Q+   +    +   
Sbjct: 989  QHESRSSQSNYG-QHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQY-SGFGQHGSGSD 1046

Query: 340  LQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCG 399
              S  GQ+        +       F    + S  +S  Q  S SS  S   Q G N    
Sbjct: 1047 QSSGFGQHG-------TGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSN---- 1095

Query: 400  QGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSAL 459
                  G  +   Q  P  S   S      S +    GFG  G      +  G SS    
Sbjct: 1096 -----SGQTSGFGQHRPG-SGQSSGFGQYGSGSGQSSGFGQHG------SGTGKSS---- 1139

Query: 460  STQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESL 519
                       QH   S     Q    +  + S ++  C   E  S P     +   + +
Sbjct: 1140 --------GFAQHEYRSG----QSSYGQHGTGSSQSSGCGQHESGSGP----TTSFGQHV 1183

Query: 520  DGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAARE 579
             G  + SS   G+ +   SGQST     Y  G+ +  G    +  Q E     ++   R+
Sbjct: 1184 SGSDNFSS--SGQHISD-SGQSTGFG-QYGSGSGQSTGLGQGESQQVES---GSTVHGRQ 1236

Query: 580  EATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPP 639
            E T     +    S      + +T   +  R              + SQ ++  +     
Sbjct: 1237 ETTHGQTINTTRHSQSGQGQSTQTGSRVTRRR-------------RSSQSENSDSEVHSK 1283

Query: 640  SNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSG----HSAAGPGFTSR 695
             +    E  H            GS   K+G       G  +GQ G    H  +G G +++
Sbjct: 1284 VSHRHSEHIHTQ---------AGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQ 1334

Query: 696  TEPSKSPGSLRYSYKDSFGSAVPRNVSGFP--QYPTGQEKGDFTGHGE 741
            T  S++ G  R+S+ D+  S V   VS  P  Q  T  + G   G  E
Sbjct: 1335 T-GSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESE 1381



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 94/367 (25%), Positives = 136/367 (37%), Gaps = 48/367 (13%)

Query: 13  NQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASE 72
           + QS   + HGSS     S + +   Q+  G+G SSG    GSG G+        +++ +
Sbjct: 460 SSQSLGYDQHGSS-----SGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQ 514

Query: 73  TSGHQGYQGFRKEAGDF-----------YYMAGNKDPVTTGTPQPPQRRPSGPVQ-SYGP 120
           +SG   +     ++  F           Y   G+    ++G  Q   R  SG  Q   G 
Sbjct: 515 SSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGS 574

Query: 121 PQGSSFGNQYGS-EGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQ 179
            Q + FG QYGS  G    F    SG G  S + Q  +     G + Y Q +S   Q   
Sbjct: 575 GQSTGFG-QYGSGSGQSSGFGQHGSGSGQSSGFGQHES---RSGQSSYGQHSSGSSQSSG 630

Query: 180 VQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRV---GQ---FGQ 233
             Q     + S Q      GQ  S SS      +  +    ++G+   V   GQ   FGQ
Sbjct: 631 YGQ-----HGSRQ--TSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQ 683

Query: 234 HYQSSASSS-------SSSSFPSPQRFSQSGQ-SYDGSYNVNAG--SQYEGHNVGS-NAQ 282
           H   S  SS       SS S    Q  S SGQ S  G + +++G  S +  H  GS  + 
Sbjct: 684 HESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSS 743

Query: 283 AYGTQSNYSYQPQSMKNFE--QAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPL 340
            +G   + S Q       E    +   G       Q     QH S+    +    +    
Sbjct: 744 GFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQ 803

Query: 341 QSQVGQY 347
            +  GQY
Sbjct: 804 STGFGQY 810



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 90/365 (24%), Positives = 128/365 (35%), Gaps = 38/365 (10%)

Query: 7   QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFG----GTGGSSGSSGSGSGGGRRGA 62
           Q      Q SY Q   GSS+   +    ++    FG    G+G S+G    GSG G+   
Sbjct: 533 QHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSG 592

Query: 63  AAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQ------ 116
                + + ++SG   ++    ++    + +G+    ++G  Q   R+ SG  Q      
Sbjct: 593 FGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ--SSGYGQHGSRQTSGFGQHGSGSS 650

Query: 117 --------SYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQ 168
                     G  Q S FG      G    F  QH    G S Y Q   G  S  S+ Y 
Sbjct: 651 QSTGFGQYGSGSGQSSGFGQHVSGSGQSSGF-GQHESRSGHSSYGQHGFG--SSQSSGYG 707

Query: 169 QQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGY---Q 225
           Q  SS  Q     Q      QS      + GQ  S S       +  +    ++G+   +
Sbjct: 708 QHGSSSGQTSGFGQHELSSGQS-----SSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHE 762

Query: 226 LRVGQ--FGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQA 283
            R GQ  +GQH   S+ SS      S Q  S  GQ   GS       QY G   G +A  
Sbjct: 763 SRSGQSSYGQHSSGSSQSSGYGQHGSRQT-SGFGQHGSGSSQSTGFGQY-GSGSGQSA-G 819

Query: 284 YGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQ 343
           +G   + S Q       E       +  GQ      Q     QH       +     +S 
Sbjct: 820 FGQHGSGSGQSSGFGQHESRS--HQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSS 877

Query: 344 VGQYN 348
            GQY+
Sbjct: 878 SGQYS 882



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 76/342 (22%), Positives = 130/342 (38%), Gaps = 53/342 (15%)

Query: 6    EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSG------SGGGR 59
            +  S HG  +S   E HG++                G TG +SG S SG      SG   
Sbjct: 1828 QAGSQHGESESIVDERHGTTH---------------GQTGDTSGHSQSGHGQSTQSGSST 1872

Query: 60   RGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRR---PSGPVQ 116
             G   +  + +S++  H G  G    +G  +  A ++   +  T     +     +G   
Sbjct: 1873 TGRRRSGHSESSDSEVHSG--GSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTT 1930

Query: 117  SYG-PPQGSSFGNQYGSEGHVGQFQAQHS---GLGGVSHYQQDYT----GPFSP--GSAQ 166
             +G P  G +      + G  G   +++S   G  GVSH    +T    G   P  GS+ 
Sbjct: 1931 EHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSV 1990

Query: 167  YQQQASSQQQQQQVQQLRQQLY-QSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
            +++  ++  Q     +     + QS Q   + TG+ AS  S     +  S +  + +G+ 
Sbjct: 1991 HERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGH- 2049

Query: 226  LRVGQFGQHYQSSASS------SSSSSFPSPQRFSQSGQSYDGSY-NVNAGSQYEGHNVG 278
               GQ G  +  S SS      ++        R + SG        +  AG +  GH+  
Sbjct: 2050 -AHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSES 2108

Query: 279  SNAQAYG----TQSNYSYQPQSMKNFEQAKI---PQGTQQGQ 313
            S+++ +     T S ++Y     ++ E        QGT  GQ
Sbjct: 2109 SDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQ 2150



 Score = 35.8 bits (81), Expect = 0.42
 Identities = 48/196 (24%), Positives = 70/196 (35%), Gaps = 19/196 (9%)

Query: 2    QSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQA-QMFQNFGGTGGSSGSSGSGSGGGRR 60
            QS +  S   G Q+S   E   S    E SP  +       G   G SGSSG G  G   
Sbjct: 2164 QSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTH 2223

Query: 61   GAAAAAAAMASETSGHQGYQGFRK--EAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSY 118
            G        A    G    +G R     G  +  + + +  + G+        SG +Q  
Sbjct: 2224 GQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGS-----HTHSGHIQG- 2277

Query: 119  GPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHY------QQDYTGPFSPGSAQYQQQAS 172
               Q  S   Q GS  H G+ +  H   G  + +      Q   TG  S  ++ +Q  +S
Sbjct: 2278 ---QAGSQQRQPGSTVH-GRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQSHSS 2333

Query: 173  SQQQQQQVQQLRQQLY 188
             +Q+    Q  +   Y
Sbjct: 2334 ERQRHGSSQVWKHGSY 2349


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
            sapiens]
          Length = 4911

 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 88/397 (22%), Positives = 152/397 (38%), Gaps = 74/397 (18%)

Query: 1548 NKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEP 1607
            +K  +Q QPPPPPP+ P  P  S     K  + R R++   P  + RK+   +    VE 
Sbjct: 6    DKSVEQPQPPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGKTAVED 65

Query: 1608 QEPEIKLKYA-TQPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKG 1666
            ++    L+   T+ + +T+ K +S                     AEE+ + ++   ++ 
Sbjct: 66   EDSMDGLETTETETIVETEIKEQS---------------------AEEDAEAEVDNSKQL 104

Query: 1667 QRSLTPPPSSTESKALPASSFMLQGPVVTESSVMGHLVC-CLCGKWASYRNMGDLFGPFY 1725
              +L    S   + +L +        V  E+ +   L   C CG+ +S    GDL     
Sbjct: 105  IPTLQRSVSEESANSLVS--------VGVEAKISEQLCAFCYCGEKSSL-GQGDL----- 150

Query: 1726 PQDYAAT----LPKNPPPKRATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLA 1781
             + +  T    LP    P    ++           SNG+             +K Q S  
Sbjct: 151  -KQFRITPGFILPWRNQPSNKKDIDDN--------SNGT------------YEKMQNSAP 189

Query: 1782 AHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQ 1841
               R +R+ RS             + C   +T+ +S+      K     +  G P+  + 
Sbjct: 190  RKQRGQRKERSPQ--------QNIVSCVSVSTQTASDDQA--GKLWDELSLVGLPDA-ID 238

Query: 1842 IPELPLDSNEFWVHEGCILWANGI-YLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCY 1900
            I  L   +   W H  C+ W+ G+  +    L  + +A+      +C+ C+  GAT+ C 
Sbjct: 239  IQALFDSTGTCWAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCC 298

Query: 1901 NKGCSFRYHYPCAIDADCLLHEENFSVRCPKHKPPLP 1937
             + C+  YHYPCA  A       +  + CP+H    P
Sbjct: 299  EEKCTQMYHYPCAAGAGTFQDFSHIFLLCPEHIDQAP 335



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 33/85 (38%), Positives = 48/85 (56%), Gaps = 2/85 (2%)

Query: 1851 EFWVHEGCILWANGIYLV-CGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYH 1909
            + WVH  C LW+  +Y    G L  ++ AL    +MKC  C + GAT GC+   C+  YH
Sbjct: 4425 DLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYH 4484

Query: 1910 YPCAIDADCLLHEENFSVRCPKHKP 1934
            + CAI A C+  ++  ++ CP HKP
Sbjct: 4485 FTCAIKAQCMFFKDK-TMLCPMHKP 4508



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 112/433 (25%), Positives = 159/433 (36%), Gaps = 89/433 (20%)

Query: 293  QPQSMKNFEQAKIPQGTQQGQQ----QQQPQQQQHPSQHVMQYTNAAT-----KLPLQSQ 343
            Q    K+ +QAKI + TQ+ +Q    QQQ QQQQ  SQH++  + + T     + PL  Q
Sbjct: 1755 QQMRQKSKQQAKI-EATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQ 1813

Query: 344  VGQYNQPEVPVRSPMQ-FHQNF---SPISNPSPAAS-----VVQSPSCSSTPS--PLMQT 392
             G  N       SP Q FH+      P S P+  +S       Q+P     PS  P+  +
Sbjct: 1814 PGNGNM------SPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDS 1867

Query: 393  GENLQCGQGSVPM----GSRNR--ILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEK 446
                Q  Q   P     GS N      + P      +  P P  H+   +       P +
Sbjct: 1868 LSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRN---SAAPVE 1924

Query: 447  RLTDPGLSSLS---ALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSK--KADSCTNS 501
              T   LSS+S    ++   AN P+ V+  L S + T     +K P + +    D    S
Sbjct: 1925 NCTP--LSSVSRPLQMNETTANRPSPVRD-LCSSSTTNNDPYAKPPDTPRPVMTDQFPKS 1981

Query: 502  EGSSQ----PEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAG 557
             G S+     E+  K P+A       +  S       RQ    S +        A   +G
Sbjct: 1982 LGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTP--APLDSG 2039

Query: 558  SSPAQGAQNEPP--------------RLNASPAAREEAT-------SPGAKDMPLSS--- 593
              P +     PP              RL+  P  R   T       S    + P S    
Sbjct: 2040 PGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPL 2099

Query: 594  DGNPKVNEKTVGVIVSRE-AMTGRVEKPGGQDKGSQEDDPAATQRP------PSNGGAKE 646
              +P VNE       SR  +  G + +P  QD  SQ   P  T RP       S+G A+ 
Sbjct: 2100 TPHPAVNESFAH--PSRAFSQPGTISRPTSQDPYSQ---PPGTPRPVVDSYSQSSGTARS 2154

Query: 647  TSHASLPQPEPPG 659
             +    P  +PPG
Sbjct: 2155 NTD---PYSQPPG 2164



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 94/457 (20%), Positives = 158/457 (34%), Gaps = 63/457 (13%)

Query: 306  PQGTQQ-GQQQQQPQQQQ----HPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSP--M 358
            PQ  QQ GQ  QQ   QQ     PS      TN   ++   S V   + P +PV SP   
Sbjct: 3473 PQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVP--DSPSIPVGSPNFS 3530

Query: 359  QFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPM------GSRNRIL 412
               Q    +S  S   S V+     + P+       +L CGQ S         GS   ++
Sbjct: 3531 SVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGSTQSLI 3590

Query: 413  QLMPQLSPTP------SMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLS-ALSTQVAN 465
            QL   + P        +     +  A   K       P   +T P    +S   ST   +
Sbjct: 3591 QLYSDIIPEEKGKKKRTRKKKRDDDAESTKA---PSTPHSDITAPPTPGISETTSTPAVS 3647

Query: 466  LPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPM--AESLDGGC 523
             P+ +      +++ P   ++   ++ +      N   +S   +   +    A S     
Sbjct: 3648 TPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKL 3707

Query: 524  SSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSS--------PAQGAQNEPPRLNASP 575
            S  +  + E ++    ++ S     +    E+ GS         P   AQ+ PP    +P
Sbjct: 3708 SMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQS-PPHSAGAP 3766

Query: 576  AAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAAT 635
            AA+ ++ +   K +  +   +  +N+K  G I S +  T              +D+    
Sbjct: 3767 AAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCT--------------KDNKLVE 3812

Query: 636  QRPPSNG----GAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPG 691
            ++ P+ G    GA+           P   GGS+  K     +   GE         A P 
Sbjct: 3813 KQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGE--------KAAPR 3864

Query: 692  FTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYP 728
               R +  +   ++ YS  D+F     +N    P  P
Sbjct: 3865 SKKRKKDEEEKQAM-YSSTDTFTHLKQQNNLSNPPTP 3900



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 114/518 (22%), Positives = 169/518 (32%), Gaps = 127/518 (24%)

Query: 157  TGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQ---PMQR 213
            +GP  P     Q   SSQ     V Q  ++L       P  T +P  + SH Q   P  +
Sbjct: 2038 SGP-GPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQ 2096

Query: 214  PSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQR-FSQSGQSYDGSYNVNAGSQY 272
            P   P  A                      + SF  P R FSQ G +     + +  SQ 
Sbjct: 2097 PPLTPHPAV---------------------NESFAHPSRAFSQPG-TISRPTSQDPYSQP 2134

Query: 273  EGHN---VGSNAQAYGT-QSN---YSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPS 325
             G     V S +Q+ GT +SN   YS  P +         P+ T      QQPQ  +  +
Sbjct: 2135 PGTPRPVVDSYSQSSGTARSNTDPYSQPPGT---------PRPTTVDPYSQQPQTPRPST 2185

Query: 326  QHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSST 385
            Q  +  T                    PV +         P   P P  SV  S    +T
Sbjct: 2186 QTDLFVT--------------------PVTNQRHSDPYAHPPGTPRPGISVPYSQP-PAT 2224

Query: 386  PSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPT-PSMMPSPNSHAAGFKGFGLEGVP 444
            P P +  G         V M +++  LQ      P  P  +  P    +           
Sbjct: 2225 PRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCS----------Q 2274

Query: 445  EKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGS 504
              R   PGLS             +T   +  S A  P  ++   P S       ++S G+
Sbjct: 2275 TPRPPGPGLS-------------DTFSRVSPSAARDPYDQSPMTPRSQ------SDSFGT 2315

Query: 505  SQPEEQLKSPMAESLDGG-CSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQG 563
            SQ    +        +G  C+SS+     + +Q SG             S+  G  P  G
Sbjct: 2316 SQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSG------------VSQLPGPVPTSG 2363

Query: 564  AQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQ 623
              +    +N + A  E+                 +  +K   +I+ ++      +  G Q
Sbjct: 2364 VTDTQNTVNMAQADTEKL----------------RQRQKLREIILQQQQQK---KIAGRQ 2404

Query: 624  DKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGG 661
            +KGSQ D PA     P      E  + +  +P PP  G
Sbjct: 2405 EKGSQ-DSPAVPHPGPLQHWQPENVNQAFTRPPPPYPG 2441


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
            sapiens]
          Length = 2191

 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 201/870 (23%), Positives = 285/870 (32%), Gaps = 186/870 (21%)

Query: 9    SYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGG--GRRGAAAAA 66
            SY G   SYP+    S+     S  Q+Q        GG   ++G G G   G + AAA+ 
Sbjct: 374  SYGG---SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430

Query: 67   AAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQ----------PPQRRPSGPVQ 116
            A  A++   H                    DP+    PQ           PQ+    P  
Sbjct: 431  AWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG 490

Query: 117  SYGPP-------------QGSSFGNQYGSEGHVGQFQAQHS--------GLGGVSHY--- 152
            SYGPP              G+  G QY  +   G    + +        G  GVS Y   
Sbjct: 491  SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQ 550

Query: 153  -QQDYTG-----PFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSS 206
             QQ Y       P  P  AQY    S Q+ Q Q Q + Q+ Y +    P A G+P     
Sbjct: 551  GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQ-QDMSQEGYGTRSQPPLAPGKPNHEDL 609

Query: 207  HLQPMQRPSTLPS-SAAGYQLRVG-----QFGQHYQSSASSSSSSSFPSPQRFSQSGQSY 260
            +L   +RPS+LP  S +   L  G             S SS    S P+   FS     +
Sbjct: 610  NLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPH 669

Query: 261  DGSYNVNAGSQYEGHNVGSN------------------AQAYGTQSNYSYQP---QSMKN 299
              S          G  VGSN                   Q  G+QS  S  P   QS   
Sbjct: 670  LSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMP 729

Query: 300  FEQA------KIPQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQV 344
             E+       + PQ  Q G QQ  P    HPS             Q  ++ T  P  SQ 
Sbjct: 730  QERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 789

Query: 345  ---GQYNQPEVPVRSPMQFHQNFSP--------------ISNPSPAASVVQSPSC----- 382
               G Y++P      P   +    P               S P  A  + + PS      
Sbjct: 790  GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849

Query: 383  -------SSTPSPLMQTGENLQCGQG-SVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAG 434
                   S TPS     G + Q G G   PM + NR  Q     +   +   S  S    
Sbjct: 850  PFPGNMSSMTPS---SPGMSQQGGPGMGPPMPTVNRKAQ-EAAAAVMQAAANSAQSRQGS 905

Query: 435  FKGFGLEGV--PEKRLTDPGLSSLSALSTQV-------ANLPNTVQHMLLSDALTPQKKT 485
            F G    G+       + P  +S S ++TQ        A + ++   + L+D ++P +  
Sbjct: 906  FPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESK 965

Query: 486  SKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSD 545
               P    KAD     EG+ QPE + K           SSSS   GE++ ++       +
Sbjct: 966  LPLP---LKADG--KEEGTPQPESKSKK----------SSSSTTTGEKITKVYELGNEPE 1010

Query: 546  --------TTYKGGASEKAGSSPAQGAQ--------------NEPPRLNASPAAREEATS 583
                     T+         S PA G +                  ++N +   RE AT+
Sbjct: 1011 RKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATN 1070

Query: 584  PGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQ--DKGSQEDDPAATQRPPSN 641
                ++  SS     + ++ +  + + E    R E+P  +    G  +  P      P+N
Sbjct: 1071 ---LNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPAN 1127

Query: 642  GGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKS 701
             G       SL  P+ P   GS        +       +   G      G  S T     
Sbjct: 1128 SG-------SLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHD 1180

Query: 702  PGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ 731
            P      + D   S+ P+  S  P  P  Q
Sbjct: 1181 P------FSDVSDSSFPKRNSMTPNAPYQQ 1204



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 139/601 (23%), Positives = 202/601 (33%), Gaps = 102/601 (16%)

Query: 42  GGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGHQGYQGF------------------- 82
           GG+GG  G  G+G+GG   GA AAAAA A+  +G  G  G+                   
Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319

Query: 83  ------------------RKEAGDFYYMAGNKDPVTTGTPQPPQ--RRPSGPVQSYGPPQ 122
                                AG F   AG     +  TP   Q    PS  ++SYG   
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379

Query: 123 GSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQ 182
              + +         Q Q+Q +  G  +  QQ   G    G     Q A++       QQ
Sbjct: 380 -PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG-MGLGKDMGAQYAAASPAWAAAQQ 437

Query: 183 LRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSS 242
                 +SH  +   T  P    S   PM  P  +      Y +      Q  QSS    
Sbjct: 438 ------RSHPAMSPGTPGPTMGRSQGSPMD-PMVMKRPQL-YGMGSNPHSQPQQSSPYPG 489

Query: 243 SSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGT--QSNYSYQPQSMKNF 300
            S   P PQR+    Q    +    AG QY       +A    T       Y  Q +  +
Sbjct: 490 GSYGPPGPQRYPIGIQG--RTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGY 547

Query: 301 -EQAKIPQGTQQGQQQQQPQQQQH-PSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPM 358
            +Q + P  +QQ Q    P Q Q+ PSQ   +Y          SQ G   + + P+    
Sbjct: 548 CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD----MSQEGYGTRSQPPLAPGK 603

Query: 359 QFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSV-PMGSRNRILQ--LM 415
             H++ + I    P++    S S    P+    T  +     GS    G ++   Q    
Sbjct: 604 PNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFS 663

Query: 416 PQLSPTPSMMP-SPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLP-----NT 469
           P  SP  S +P  P+    G        V   +     +S  S   +Q+   P      +
Sbjct: 664 PHASPHLSSIPGGPSPSPVG------SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSES 717

Query: 470 VQHMLLSDALTPQKK-----TSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCS 524
             H  LS +  PQ++     T + P  ++     T    S  P     SP  + +  G S
Sbjct: 718 SSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP-----SPGGQ-MHAGIS 771

Query: 525 SSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP 584
           S              Q ++S  TY    S+       QG  + PP  +  P+A      P
Sbjct: 772 SF-------------QQSNSSGTYGPQMSQYG----PQGNYSRPPAYSGVPSASYSGPGP 814

Query: 585 G 585
           G
Sbjct: 815 G 815



 Score = 37.4 bits (85), Expect = 0.15
 Identities = 47/215 (21%), Positives = 74/215 (34%), Gaps = 31/215 (14%)

Query: 506 QPEEQLKSPMAESLD-GGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGS---SPA 561
           Q ++Q + P++ +   GG    +   G  + Q   Q   +  +  GG ++  G    S  
Sbjct: 67  QQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQ--PQHGGAKDSAAGGQADPPGPPLLSKP 124

Query: 562 QGAQNEPPRLNASPAAREEATSPGA---KDMPLSSDGN-------PKVNEKTVGVIVSRE 611
               + PP++      R E    GA   +  P++  G        P+ N        +  
Sbjct: 125 GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG 184

Query: 612 AMTGRV----EKPGGQDK---GSQEDDPAATQRPPSNGGAKETSHASLPQPE-------- 656
              GR     ++ GGQ     G      AA    P +    + SH   P  +        
Sbjct: 185 GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYS 244

Query: 657 PPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPG 691
            PG GG  G   G    +  G G G +G   AG G
Sbjct: 245 RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 203/1053 (19%), Positives = 345/1053 (32%), Gaps = 176/1053 (16%)

Query: 302  QAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFH 361
            Q ++ Q  QQ QQQQQ QQQQ   QH +   N+     L    G   QP   +  P    
Sbjct: 49   QQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNS-----LGGAGGGAPQPGPDMEQPQHGG 103

Query: 362  QNFSPISNPS--PAASVVQSPSCSSTPSPLM---QTGENLQCGQGSVPMGSRNRILQLMP 416
               S     +  P   ++  P       P M     G     G G+  +G++   +  +P
Sbjct: 104  AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGA--LGTQQPPV-AVP 160

Query: 417  QLSPTPSMMPSPNSH------AAGFKG------FGLEGVPEKRLTDPGLSSLSALSTQVA 464
                 P+ +P  N++      A+G  G      F   G  +     PG+  + + S   A
Sbjct: 161  GGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQ----SPGMGMMHSASAAAA 216

Query: 465  NLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCS 524
              P ++  +  S    P  + +  P  S+         G                 GG  
Sbjct: 217  GAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG----------------GGGG 260

Query: 525  SSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP 584
             S    G       G    +       A+  AG     G            + R++    
Sbjct: 261  GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--- 317

Query: 585  GAKDMPLSSDGNPKVNEKTVGVIVSR-EAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGG 643
            G   M     G   +++   G      +   G+ + P G      +   + +    S GG
Sbjct: 318  GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGG 377

Query: 644  A-KETSHASLPQPEP--PGGGGSKGNKNGDNNSNHNGEGNGQ---SGHSAAGPGFTS--- 694
            +  E S  S P P P  P    +             G G G+   + ++AA P + +   
Sbjct: 378  SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ 437

Query: 695  RTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQ-YPTG-------QEKGDFTGHGERKGRN 746
            R+ P+ SPG+   +   S GS +   V   PQ Y  G       Q+   + G        
Sbjct: 438  RSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497

Query: 747  EKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPN--VLVSQTNELASRGLL 804
            +++P  +Q    G         + +  ++     S + T +    ++  Q  +    G  
Sbjct: 498  QRYPIGIQGRTPG---------AMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYC 548

Query: 805  NKS----IGSLLENPHWGPWERKSSSTAPEMKQ----INLTDYPIPRKFEIEPQSSAHEP 856
             +          + PH  P  +   S + +  Q    ++   Y    +  + P    HE 
Sbjct: 549  QQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHED 608

Query: 857  GGSL-SERRSVICDIS------------PLRQIVRDPGA-HSLGHMSADTRIGRNDRLNP 902
               +  ER S + D+S             L   V   G+  S G  S   +   +   +P
Sbjct: 609  LNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASP 668

Query: 903  TLSQSVILPGG-----LVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPP-SI 956
             LS    +PGG     + S     +S+SG I       S+        +S    HP  S 
Sbjct: 669  HLSS---IPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQ 725

Query: 957  KHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKL 1016
                       G   +  ++ YGPQ + P+                              
Sbjct: 726  SPMPQERGFMAGTQRNPQMAQYGPQQTGPS------------------------------ 755

Query: 1017 KMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTP----FSPNSETLASAYHANTRAHAY 1072
             MSP  S  PGG    M+  ++  +++N S  + P    + P         ++   + +Y
Sbjct: 756  -MSPHPS--PGG---QMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASY 809

Query: 1073 GDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRV 1132
              P  G+   +    QM+ Q P +          G +   +    G +  P         
Sbjct: 810  SGPGPGMG--ISANNQMHGQGPSQ--------PCGAVPLGRMPSAGMQNRPFPGNMSSMT 859

Query: 1133 -RSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDL 1191
              SP  + + G   GPP+ T  +  AQEA   +M +    N     +     + +S   L
Sbjct: 860  PSSPGMSQQGGPGMGPPMPTV-NRKAQEAAAAVMQA--AANSAQSRQGSFPGMNQS--GL 914

Query: 1192 SRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVML---RLPGQEDHSSQ 1248
               +SP         S      PP     + +A A  +S   SV L     PG+    S+
Sbjct: 915  MASSSPYSQPMNNSSSLMNTQAPP-----YSMAPAMVNSSAASVGLADMMSPGE----SK 965

Query: 1249 NPLIMRRRVRSFISPIPSKRQSQDVKNSSTEDK 1281
             PL ++   +   +P P  +  +   +++T +K
Sbjct: 966  LPLPLKADGKEEGTPQPESKSKKSSSSTTTGEK 998



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 37/140 (26%), Positives = 50/140 (35%), Gaps = 20/140 (14%)

Query: 150 SHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQ 209
           +H+   +        A  QQ    QQQQQQ QQ +QQ  Q   P+        +     Q
Sbjct: 32  AHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQ 91

Query: 210 PMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVN-- 267
           P            G  +   Q G    S+A   +    P P   S+ G   D    +   
Sbjct: 92  P------------GPDMEQPQHGGAKDSAAGGQADP--PGPPLLSKPGDEDDAPPKMGEP 137

Query: 268 AGSQYEGHNVGSNAQAYGTQ 287
           AG +YE   +G    A GTQ
Sbjct: 138 AGGRYEHPGLG----ALGTQ 153



 Score = 35.8 bits (81), Expect = 0.42
 Identities = 58/257 (22%), Positives = 85/257 (33%), Gaps = 22/257 (8%)

Query: 118  YGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFS-PGSAQYQQQASSQQQ 176
            YGPP     G+ Y  + +  Q Q  ++  GG       Y+GP   P   QY    S ++ 
Sbjct: 1322 YGPPAKRHEGDMYNMQ-YSSQQQEMYNQYGG------SYSGPDRRPIQGQYPYPYSRERM 1374

Query: 177  QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRP-STLPSSAAGYQLRVGQFG--Q 233
            Q   Q       Q+H   PQ  G P  SSS   P Q   +        YQ R G  G  Q
Sbjct: 1375 QGPGQ------IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQ 1428

Query: 234  HYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQ 293
                   + +       QR +   Q      +V+    Y   +          Q +Y   
Sbjct: 1429 APPYPGMNRTDDMMVPDQRINHESQ---WPSHVSQRQPYMSSSASMQPITRPPQPSYQTP 1485

Query: 294  PQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVP 353
            P    +  +A  P   Q+  + +     + P    M+       +P     G   QP  P
Sbjct: 1486 PSLPNHISRAPSPASFQRSLENRM-SPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP-P 1543

Query: 354  VRSPMQFHQNFSPISNP 370
            +R  + F       S P
Sbjct: 1544 IRREITFPPGSVEASQP 1560


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 44/162 (27%), Positives = 64/162 (39%), Gaps = 22/162 (13%)

Query: 1793 EDCGGGPRSLSRGLPCKKAATEGSSEKTVLDSK---PSVPTTSEGGPE--LELQIPELPL 1847
            +DC GGP        C + +  G  E    +     P  P  S GG     E  +P   L
Sbjct: 56   QDCSGGPVRRCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGGSPGPNEAVLPSEDL 115

Query: 1848 DSNEF----------------WVHEGCILWANGIYLVCG-RLYGLQEALEIAREMKCSHC 1890
                F                W H  C  W+ G++   G  L G+ +A+      +CSHC
Sbjct: 116  SQIGFPEGLTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHC 175

Query: 1891 QEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPKH 1932
               GA++ C + GC   YH+PCA  +   L  +   + CP+H
Sbjct: 176  TRLGASIPCRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEH 217



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 34/89 (38%), Positives = 45/89 (50%), Gaps = 2/89 (2%)

Query: 1851 EFWVHEGCILWANGIYLVCG-RLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYH 1909
            + WVH  C LW+  +Y   G  L  ++ AL      KCS CQ  GAT  C    C   YH
Sbjct: 5055 DLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYH 5114

Query: 1910 YPCAIDADCLLHEENFSVRCPKHKPPLPC 1938
            + CAI A C+  ++  ++ CP HK   PC
Sbjct: 5115 FACAIRAKCMFFKDK-TMLCPMHKIKGPC 5142



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 140/626 (22%), Positives = 205/626 (32%), Gaps = 128/626 (20%)

Query: 103  TPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVS--HYQQDYTGPF 160
            +PQPPQ    GP    GP Q             V   Q QH G  G    H Q   T   
Sbjct: 3791 SPQPPQ----GPQGMLGPAQ-------------VAVLQQQHPGALGPQGPHRQVLMTQSR 3833

Query: 161  SPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSS 220
               S Q  QQ       + V   +QQ  Q HQ      G      SHLQ           
Sbjct: 3834 VLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGL-----SHLQ----------- 3877

Query: 221  AAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSN 280
                Q  +   GQ   S+    S       Q+  Q  Q            Q +   +   
Sbjct: 3878 ----QSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQL----------QQQQQQQLQQQ 3923

Query: 281  AQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNA--ATKL 338
             Q    Q     Q Q ++  +Q ++ Q  QQ QQQQQ QQQQ   Q   Q       ++ 
Sbjct: 3924 QQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRT 3983

Query: 339  PLQSQVGQYNQPEVPVRSPMQFHQNFSP----------------ISNPSPAASVVQSPSC 382
             L  Q  Q  Q  +    P +  Q+FS                   +P+ ++   + PS 
Sbjct: 3984 LLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPST 4043

Query: 383  -SSTPSPLMQTGENLQCGQGSV--PMGSRNRILQLMPQLSPTPS--------MMPSPNS- 430
                P  +  T E++    G V   +   +++L + PQ  P PS         +P     
Sbjct: 4044 HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQ 4103

Query: 431  -----HAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKT 485
                 H AG    G  G             L+  S  + + P ++   LL     PQ+  
Sbjct: 4104 QVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLG----PQQPM 4159

Query: 486  SKRPSSS-------KKADSCTNSEG---------SSQPEEQLKSPMAESLDGGCSSSSED 529
             +RP  +       K      + +G           Q   QL+  +A++      S  + 
Sbjct: 4160 LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219

Query: 530  QGERVRQLSGQSTSSDTTYKGGASEKAG--SSPAQGAQNEPPRLNASPAAREEATSP--- 584
            Q  +   +  Q   S    +    ++ G  +SP QG     P+L   P  +   T P   
Sbjct: 4220 QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ---TGPLQE 4276

Query: 585  -GAKDMPLSSDGNPKV----NEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAA----- 634
             GA   P    G P++       + G ++     T     P    + SQ   P++     
Sbjct: 4277 LGAGPRP---QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTE 4333

Query: 635  TQRPPSNGGAKETSHASLPQPEPPGG 660
             Q PP++ G   T     P  EPP G
Sbjct: 4334 AQLPPTHPG---TPKPQGPTLEPPPG 4356



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 123/542 (22%), Positives = 186/542 (34%), Gaps = 63/542 (11%)

Query: 146  LGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQP--LPQATGQPAS 203
            L  V   Q+++T   +    + QQQ   QQQQQQ       L  S  P  L +  GQ   
Sbjct: 3578 LDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLP 3637

Query: 204  SSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGS 263
                LQP Q P      A G +L  G      Q      +++     Q+    G    GS
Sbjct: 3638 GHG-LQPPQGPP--GGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGA---GS 3691

Query: 264  YNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQ--- 320
                +G  + G+      ++ G  S    + Q     ++ ++ Q  QQ QQQQQ QQ   
Sbjct: 3692 LAGPSGGFFPGNLA---LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLL 3748

Query: 321  -----QQHPSQHVMQYTNAAT------KLPLQSQVG---QYNQPEVPVRSP--MQFHQNF 364
                 QQ   Q     TN A        +P  S  G   Q   P+ P + P  M      
Sbjct: 3749 GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQ-PPQGPQGMLGPAQV 3807

Query: 365  SPISNPSPAASVVQSP--SCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTP 422
            + +    P A   Q P      T S ++ + +  Q GQG            LM     T 
Sbjct: 3808 AVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQG------------LMGHRLVTA 3855

Query: 423  SMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQ 482
                    H       GL  + +  ++  G   LSA    + +L    Q   L      Q
Sbjct: 3856 QQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSA--QPMGSLQQLQQQQQLQQQQQLQ 3913

Query: 483  KKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQST 542
            ++  ++    ++           Q ++QL+    + L        + Q ++ +Q   Q  
Sbjct: 3914 QQQQQQLQQQQQLQQ--QQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQ 3971

Query: 543  SSDTTYKGGASEKAGSSPAQGAQNE---PPRLNASPAAREEATSPGAKDMPLSSDGNPKV 599
                        +   SP Q  Q +    P + A P   +  +SPGA    L   G    
Sbjct: 3972 QQQMGLLN--QSRTLLSPQQQQQQQVALGPGMPAKPL--QHFSSPGALGPTLLLTGK--- 4024

Query: 600  NEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQ----RPPSNGGAKETSHASLPQP 655
             + TV   VS EA  G     GG        +  AT+    +P  +G ++       PQP
Sbjct: 4025 EQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQP 4084

Query: 656  EP 657
            +P
Sbjct: 4085 QP 4086



 Score = 35.0 bits (79), Expect = 0.72
 Identities = 69/336 (20%), Positives = 115/336 (34%), Gaps = 43/336 (12%)

Query: 349  QPEVPVRSPMQFH----QNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVP 404
            +P  P  SP+  H    QN SP S  SP A  +  PS  S    ++   +  +  +    
Sbjct: 1018 EPLPPQCSPLLQHSLVPQN-SPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETE 1076

Query: 405  MGSRNRILQLMPQL-SPTPSMM-------PSPNSHAAGFKGFGLEGVPEKRLTDPGLSSL 456
              S      L P   SP PS M       PSP      F G G +  P   +  PG    
Sbjct: 1077 KVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQP- 1135

Query: 457  SALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMA 516
                 +    P ++   L    +    +     +  +    C  + G   P E+ + P A
Sbjct: 1136 -----EPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRA 1190

Query: 517  ESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASP- 575
                   +  +  + + V ++S  S    +    G+    GS   +G  +    L  S  
Sbjct: 1191 PVAP---TPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTD 1247

Query: 576  --AAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPA 633
               AR+E +      + L +D  P+ ++  +    +  A++G          G  E +  
Sbjct: 1248 VSPARDEGS------LRLCTDSLPETDDSLL--CDAGTAISG----------GKAEGEKG 1289

Query: 634  ATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNG 669
              +  P+    K+   +S P    P GG   G   G
Sbjct: 1290 RRRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRGRG 1325



 Score = 35.0 bits (79), Expect = 0.72
 Identities = 63/236 (26%), Positives = 93/236 (39%), Gaps = 24/236 (10%)

Query: 106  PPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPG-S 164
            PP    S P  S+G  Q S      G    V + +   +G+G  S    +  G   PG S
Sbjct: 2618 PPAPDGSLPYLSHGASQRS------GITSPVEKREDPGTGMGS-SLATAELPGTQDPGMS 2670

Query: 165  AQYQQQASSQQQQQQVQQL--RQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAA 222
               Q +   Q+Q+Q++++L  RQQ+ ++   L Q     A+++  + P       PSS A
Sbjct: 2671 GLSQTELEKQRQRQRLRELLIRQQIQRN--TLRQEKETAAAAAGAVGPPGSWGAEPSSPA 2728

Query: 223  GYQLRVGQF---GQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGS 279
              QL  GQ    G   +SS      S    P     S  S D        +     +V S
Sbjct: 2729 FEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNS 2788

Query: 280  NAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAA 335
                 G+Q+ Y   P          +P    Q QQQQ  QQQQ  +   M++  +A
Sbjct: 2789 RQLVGGSQAFYQRAPYP------GSLPL---QQQQQQLWQQQQATAATSMRFAMSA 2835


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 65.1 bits (157), Expect = 7e-10
 Identities = 82/284 (28%), Positives = 106/284 (37%), Gaps = 59/284 (20%)

Query: 166 QYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
           Q QQQ   QQQQQQ QQ +QQ  Q+  P+ Q             PMQ+P   PS A   Q
Sbjct: 245 QLQQQ---QQQQQQQQQQQQQALQAQPPIQQP------------PMQQPQPPPSQALPQQ 289

Query: 226 LRVGQFGQHYQSSASSSSSSSFPSPQR--FSQSGQSYDGSYNVNAGSQYEGHNVGSNAQA 283
           L+     QH+Q           P PQ+   +Q+  S           Q +   + S AQA
Sbjct: 290 LQQMHHTQHHQPP---------PQPQQPPVAQNQPS-------QLPPQSQTQPLVSQAQA 333

Query: 284 YGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQ----------HVMQYTN 333
              Q  Y+  P      +  + P   QQ   Q Q QQQQ   Q           V   T 
Sbjct: 334 LPGQMLYTQPP-----LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITE 388

Query: 334 A--------ATKLPLQSQVGQYNQPEVPV-RSPM-QFHQNFSP-ISNPSPAASVVQSPSC 382
           A          + P  + V       +P+ R PM Q  Q+  P +S+PSP   V    S 
Sbjct: 389 ALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSM 448

Query: 383 SSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMP 426
              P P  Q G+       +V  G        +P  SP PS  P
Sbjct: 449 PPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP 492



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 110/499 (22%), Positives = 180/499 (36%), Gaps = 102/499 (20%)

Query: 111 PSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHS----GLGGVSHYQQDYTGPFSPGSAQ 166
           P GP QS G           GS G +GQ  +       G  G++ +        +P +  
Sbjct: 103 PRGPGQSLGG---------MGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQL 153

Query: 167 YQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQL 226
             QQ + QQQQQQ QQ +QQ             Q A+     Q  Q+             
Sbjct: 154 QLQQVALQQQQQQ-QQFQQQ-------------QQAALQQQQQQQQQ------------- 186

Query: 227 RVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGT 286
                 Q +Q+  S+         Q+  Q  Q            Q + H +  + Q    
Sbjct: 187 ------QQFQAQQSAMQQQFQAVVQQQQQLQQQ----------QQQQQHLIKLHHQ---N 227

Query: 287 QSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQ-------YTNAATKLP 339
           Q     Q Q ++   Q ++ Q  QQ QQQQQ QQQ   +Q  +Q           +  LP
Sbjct: 228 QQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287

Query: 340 LQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPS------CSSTPSPLMQTG 393
            Q Q   + Q   P   P Q      P++   P+    QS +        + P  ++ T 
Sbjct: 288 QQLQQMHHTQHHQPPPQPQQ-----PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342

Query: 394 ENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEK------- 446
             L+  +   PM  +   +Q  PQ+    + + +  + AA     G++ + E        
Sbjct: 343 PPLKFVR--APMVVQQPPVQ--PQVQQQQTAVQT--AQAAQMVAPGVQMITEALAQGGMH 396

Query: 447 -RLTDPGLSSLSALSTQVANLPNTVQHML-LSDALTPQKKTSKRPSSSKKADSCTNSEGS 504
            R   P  +++SA+ +  +++P   Q M  +S +  P   +   PS  ++  +  +    
Sbjct: 397 IRARFPPTTAVSAIPS--SSIPLGRQPMAQVSQSSLPMLSS---PSPGQQVQTPQSMPPP 451

Query: 505 SQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGA 564
            QP  Q   P ++      S  +      +   S Q + S  T +   + +  S P+ G 
Sbjct: 452 PQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTAR---TPQNFSVPSPGP 508

Query: 565 QNEP--PRLNASPAAREEA 581
            N P  P    SPA   +A
Sbjct: 509 LNTPVNPSSVMSPAGSSQA 527



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 10/75 (13%)

Query: 1549 KQKKQQQPP--PPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVE 1606
            +Q  Q QPP   PP Q PQ P   A   P+  +Q    +  +P  QP      Q  P+ +
Sbjct: 261  QQALQAQPPIQQPPMQQPQPPPSQA--LPQQLQQMHHTQHHQPPPQP------QQPPVAQ 312

Query: 1607 PQEPEIKLKYATQPL 1621
             Q  ++  +  TQPL
Sbjct: 313  NQPSQLPPQSQTQPL 327


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 64.7 bits (156), Expect = 9e-10
 Identities = 76/263 (28%), Positives = 98/263 (37%), Gaps = 57/263 (21%)

Query: 166 QYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
           Q QQQ   QQQQQQ QQ +QQ  Q+  P+ Q             PMQ+P   PS A   Q
Sbjct: 245 QLQQQ---QQQQQQQQQQQQQALQAQPPIQQP------------PMQQPQPPPSQALPQQ 289

Query: 226 LRVGQFGQHYQSSASSSSSSSFPSPQR--FSQSGQSYDGSYNVNAGSQYEGHNVGSNAQA 283
           L+     QH+Q           P PQ+   +Q+  S           Q +   + S AQA
Sbjct: 290 LQQMHHTQHHQPP---------PQPQQPPVAQNQPS-------QLPPQSQTQPLVSQAQA 333

Query: 284 YGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQ 343
              Q  Y+  P      +  + P   QQ   Q Q QQQ    Q  +Q   AA  +    Q
Sbjct: 334 LPGQMLYTQPP-----LKFVRAPMVVQQPPVQPQVQQQ----QTAVQTAQAAQMVAPGVQ 384

Query: 344 VGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSV 403
           V Q + P                +S+PSP   V    S    P P  Q G+       +V
Sbjct: 385 VSQSSLP---------------MLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNV 429

Query: 404 PMGSRNRILQLMPQLSPTPSMMP 426
             G        +P  SP PS  P
Sbjct: 430 SSGPAPSPSSFLPSPSPQPSQSP 452



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 113/467 (24%), Positives = 151/467 (32%), Gaps = 146/467 (31%)

Query: 111 PSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHS----GLGGVSHYQQDYTGPFSPGSAQ 166
           P GP QS G           GS G +GQ  +       G  G++ +        +P +  
Sbjct: 103 PRGPGQSLGG---------MGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQL 153

Query: 167 YQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQL 226
             QQ + QQQQQQ QQ +QQ             Q A+     Q  Q+             
Sbjct: 154 QLQQVALQQQQQQ-QQFQQQ-------------QQAALQQQQQQQQQ------------- 186

Query: 227 RVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGT 286
                 Q +Q+  S+         Q+  Q  Q            Q + H +  + Q    
Sbjct: 187 ------QQFQAQQSAMQQQFQAVVQQQQQLQQQ----------QQQQQHLIKLHHQ---N 227

Query: 287 QSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQ--------------------------- 319
           Q     Q Q ++   Q ++ Q  QQ QQQQQ Q                           
Sbjct: 228 QQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287

Query: 320 ---QQQHPSQHVMQ---------YTNAATKLPLQSQV-----------GQ--YNQPEVP- 353
              QQ H +QH              N  ++LP QSQ            GQ  Y QP +  
Sbjct: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKF 347

Query: 354 VRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPM------GS 407
           VR+PM   Q       P     V Q  +   T          +Q  Q S+PM      G 
Sbjct: 348 VRAPMVVQQ-------PPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQ 400

Query: 408 RNRILQLMPQLSPTPSMMP-SPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANL 466
           + +  Q MP   P PS  P  P+S        G    P   L  P        S Q +  
Sbjct: 401 QVQTPQSMPP-PPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSP--------SPQPSQS 451

Query: 467 PNTVQHMLLSDALTPQKKTSKRP---SSSKKADSCTNSEGSSQPEEQ 510
           P T        A TPQ  +   P   ++     S  +  GSSQ EEQ
Sbjct: 452 PVT--------ARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQ 490



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 58/288 (20%), Positives = 103/288 (35%), Gaps = 18/288 (6%)

Query: 1419 PANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGR 1478
            P  Q+  +++P P  S+     +     T+ H +     ++PP A     SQ P  +Q +
Sbjct: 268  PPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH-QPPPQPQQPPVAQNQP-SQLPPQSQTQ 325

Query: 1479 PDGSLGGTAP--LIF--PDSKNV-PPVGILAPEANPKAEEKENDTVTISPKQEGFP---- 1529
            P  S     P  +++  P  K V  P+ +  P   P+ ++++    T    Q   P    
Sbjct: 326  PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQV 385

Query: 1530 PKGYFP--SGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQR-QRRER 1586
             +   P  S    G+ + +        QP P P QP   P  +    P P          
Sbjct: 386  SQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPS 445

Query: 1587 RKPGAQPRKRKTKQ--AVPIVEPQEPEIKLKYATQPLDKTDAKNKSFYPYIHVVNKC--E 1642
             +P   P   +T Q  +VP   P    +       P   + A+ + +   +  ++K    
Sbjct: 446  PQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEP 505

Query: 1643 LGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQ 1690
            L  +   I+  E+ +  L + +     LT P      K L      L+
Sbjct: 506  LRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALE 553



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 10/75 (13%)

Query: 1549 KQKKQQQPP--PPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVE 1606
            +Q  Q QPP   PP Q PQ P   A   P+  +Q    +  +P  QP      Q  P+ +
Sbjct: 261  QQALQAQPPIQQPPMQQPQPPPSQA--LPQQLQQMHHTQHHQPPPQP------QQPPVAQ 312

Query: 1607 PQEPEIKLKYATQPL 1621
             Q  ++  +  TQPL
Sbjct: 313  NQPSQLPPQSQTQPL 327


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 298/1478 (20%), Positives = 478/1478 (32%), Gaps = 288/1478 (19%)

Query: 184  RQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSS 243
            +Q+L  SH P  + +G+P       QP    S    +    Q   G+      S+ S   
Sbjct: 84   KQELDSSHPP--KQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRS----PSTISLKE 137

Query: 244  SSSFPSPQRFSQSGQSYDGSYNVNAGS-------QYEGHNVGSNAQAYGTQSNYSYQPQS 296
            S S    +   +S         VNA S       ++   ++ S+++A   ++    + Q 
Sbjct: 138  SKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETT---KKQK 194

Query: 297  MKNFEQAKIPQGTQQGQQQQQPQQ----QQHPSQHVMQYTNAATKLPLQSQVGQYNQPEV 352
            +   EQ K P+G  +   QQQP +    QQ P +  +Q       +  Q       QPE 
Sbjct: 195  VVQKEQGK-PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQ-------QPE- 245

Query: 353  PVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRIL 412
             ++S         P     P     Q+P       PL +     Q  Q  +  G    + 
Sbjct: 246  KIKS--------QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES--VK 295

Query: 413  QLMPQLSPTPSMMPSPNSHAAGFKGFGL-EGVPEKRLTDPGLSSLSALSTQVANLPNTVQ 471
              +P  S  P   P+P    A   G    +  P K    P     S L+  +A  P TV+
Sbjct: 296  PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQP-----SGLTKPLAQQPGTVK 350

Query: 472  HMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQG 531
              +     T   K   +P    K  +     GS +P  +   P A +   G         
Sbjct: 351  PPVQPPGTT---KPPAQPLGPAKPPA--QQTGSEKPSSEQPGPKALAQPPGVG------- 398

Query: 532  ERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPL 591
                             K  A +   + P       P  L   P  +  A +PG    P+
Sbjct: 399  -----------------KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441

Query: 592  SSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHAS 651
               G  K+  +  G   +    TG  + P      SQ   PA  + PP   G  +     
Sbjct: 442  QQPGPGKIPAQQAGPGKTSAQQTGPTKPP------SQLPGPA--KPPPQQPGPAK----- 488

Query: 652  LPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKD 711
             P P+ PG       + G  ++    +  G +  S   PG T    PS+ P         
Sbjct: 489  -PPPQQPGSAKPPSQQPG--STKPPPQQPGPAKPSPQQPGSTK--PPSQQP--------- 534

Query: 712  SFGSAVPRNVSGFPQYPTGQEKG---DFTGHGERKGRNEKFPSLLQEVLQGYH------- 761
              GSA P      P  P+ Q+       TG G+        PS  Q   QG         
Sbjct: 535  --GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLC 592

Query: 762  -------HHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNE-LASRGLLNKSIGSLLE 813
                   H P++    +  E Q    SL G   PN  +++  E L     + +++G    
Sbjct: 593  NTTELLLHVPEKANFNTCTECQTTVCSLCG-FNPNPHLTEVKEWLCLNCQMKRALG---- 647

Query: 814  NPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPL 873
                G      SS  P++K   +T      K   +PQ ++ +   +  +  S   +    
Sbjct: 648  ----GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP 703

Query: 874  RQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPG---------------GLVSME 918
              +V+ P  H      A      +    P   +   +P                 +V   
Sbjct: 704  PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763

Query: 919  TKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDY 978
            T L S S    + D   SK Q+    K +      P +K +S    A P  +   +    
Sbjct: 764  TDLVSSSSATTKPDIPSSKVQSQAEEKTT------PPLKTDS----AKPSQSFPPTGEKV 813

Query: 979  GPQDSRPTP-------MRRVPGRVGGREGMRGRSPSQYHDFAEK--LKMS--PGRSRGPG 1027
             P DS+  P       +   PG     +G +   P Q  +  +K   KMS  P     P 
Sbjct: 814  SPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873

Query: 1028 GDPHHMNPHMTFSERANRSSLHTP-FSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYK 1086
            G P    P  T  +     ++ TP  SP  +  +  +  N      G       SQ    
Sbjct: 874  GSPTPPGPRPTAGQ-----TVPTPQQSPKPQEQSRRFSLN-----LGSITDAPKSQPTTP 923

Query: 1087 RQMYQQQPEEYKDWSSGSAQGVIAAA----QHRQEGPRKSPRQQQFLDRVRSPLKNDKDG 1142
            ++    +   +       A  +I+ A     H Q GP    +Q        +P  + +  
Sbjct: 924  QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ--------APAPS-QPP 974

Query: 1143 MMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSG 1202
               GPP  T   P A             P K + +K      +E+    + +  P     
Sbjct: 975  TSQGPPKSTGQAPPA-------------PAKSIPVK------KETKAPAAEKLEPKAEQA 1015

Query: 1203 PPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFIS 1262
            P    ++    PP   D   L    Q +   + + + P  E   S  PL          +
Sbjct: 1016 PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE---STCPLCK--------T 1064

Query: 1263 PIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQ---------------- 1306
             +    +     N+ TE K ++ +         FN   HL+  Q                
Sbjct: 1065 ELNIGSKDPPNFNTCTECKNQVCNLC------GFNPTPHLTEIQEWLCLNCQTQRAISGQ 1118

Query: 1307 --DIKSIPKRDSSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNI 1364
              DI+ +P   S      P +   P  T +S  KT + P  K         + K     +
Sbjct: 1119 LGDIRKMPPAPS-----GPKASPMPVPTESSSQKTAVPPQVK---------LVKKQEQEV 1164

Query: 1365 RRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQEL 1424
            +  A     E   +T++++ I      PP      +   D ++ + ++  D  S     L
Sbjct: 1165 KTEAEKVILEKVKETLSMEKI------PP------MVTTDQKQEESKLEKDKAS----AL 1208

Query: 1425 HVEKPLPRS-----SEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQK-----PGS 1474
              +KPLP        EE   S + K   E    T    K  P A TS   ++        
Sbjct: 1209 QEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQ 1268

Query: 1475 NQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYF 1534
             Q   +   G  AP    + K         P   P++  KE+D  T + K++  PP    
Sbjct: 1269 VQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAK 1328

Query: 1535 PSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSAD 1572
            P   + G+       +K+  +      Q P+ P+G +D
Sbjct: 1329 PDQVEPGKE----KTEKEDDKSDTSSSQQPKSPQGLSD 1362



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 118/535 (22%), Positives = 187/535 (34%), Gaps = 97/535 (18%)

Query: 1198 AKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLR--LPGQEDHSSQNPLIMRR 1255
            +KSS  P  +S K+   P +     L++A +  KP  ++ +  L G     ++ P     
Sbjct: 673  SKSSPQPQQTSPKKDAAPKQD----LSKAPEPKKPPPLVKQPTLHGSPSAKAKQP----P 724

Query: 1256 RVRSFISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRD 1315
               S   P P K  S      S +DK  +    K    K       L  S    + P   
Sbjct: 725  EADSLSKPAPPKEPSVP----SEQDKAPVA-DDKPKQPKMVKPTTDLVSSSSATTKPDIP 779

Query: 1316 SSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEA 1375
            SSK     + +  P +   S   ++  PP   +       V    S  I R AS +    
Sbjct: 780  SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK-------VSPFDSKAIPRPASDSK--- 829

Query: 1376 GGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSE 1435
                     I+S      E       D   +K + + A   +SP        KP+P+ S 
Sbjct: 830  ---------IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA----KPMPKGSP 876

Query: 1436 EWRGSVDDKVKTETHAETVTAGKEPP-------------GAMTSTTSQKPGSNQGRPDGS 1482
               G         T  +TV   ++ P             G++T     +P + Q    G 
Sbjct: 877  TPPGP------RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930

Query: 1483 LGGTAPLIFPDSKN-VPPVGILAP--EANPKAEEKENDTVTISPKQEGFPPK--GYFPSG 1537
            L G    IF  + N +   G   P  ++ P A  K+    +  P  +G PPK  G  P  
Sbjct: 931  LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG-PPKSTGQAPPA 989

Query: 1538 KKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRK 1597
              K  P+    K    ++  P   Q P +     + +P P K     + +   A+P+   
Sbjct: 990  PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIK-----DSKSLTAEPQ--- 1041

Query: 1598 TKQAVPIVEPQEPEIKLKYATQPLDKTDAK-NKSFYPYIHVVNKCELGAVCTIINAE--- 1653
             K  +P    + P+ +   +T PL KT+        P  +   +C+   VC +       
Sbjct: 1042 -KAVLPTKLEKSPKPE---STCPLCKTELNIGSKDPPNFNTCTECK-NQVCNLCGFNPTP 1096

Query: 1654 --EEEQTKLVRGRKGQRSLT--------PPPSSTESKALPASSFMLQGPVVTESS 1698
               E Q  L    + QR+++         PP+ +  KA P        PV TESS
Sbjct: 1097 HLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPM-------PVPTESS 1144



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 150/681 (22%), Positives = 216/681 (31%), Gaps = 86/681 (12%)

Query: 96  KDPVTT-GTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQ 154
           K PV   GT +PP + P GP +   PP   +   +  SE    +  AQ  G+G     Q 
Sbjct: 350 KPPVQPPGTTKPPAQ-PLGPAK---PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405

Query: 155 DYTGPFSPGSAQYQQQASSQQQ---QQQVQQLRQQLYQSHQPLP-----QATGQPASSSS 206
              GP  P + Q        QQ   Q   +          QP P     Q  G   +S+ 
Sbjct: 406 ---GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462

Query: 207 HLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSS-----SSSFPSPQRFSQSGQSYD 261
              P + PS LP  A     + G      Q   S+        S+ P PQ+   +  S  
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522

Query: 262 GSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQ 321
              +    SQ  G    S  Q    + +     + +      K  Q        +QP  Q
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582

Query: 322 QHPSQ--HVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQS 379
             P     +   T     +P ++      + +  V S   F        NP+P  + V+ 
Sbjct: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGF--------NPNPHLTEVKE 634

Query: 380 PSC----------------SSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTP- 422
             C                 S+P P ++T         S    S  +  Q  P+    P 
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTT---SAVSKSSPQPQQTSPKKDAAPK 691

Query: 423 ---SMMPSPNSHAAGFKGFGLEGVPE-KRLTDPGLSSLSALST-QVANLPNTVQHMLLSD 477
              S  P P       K   L G P  K    P   SLS  +  +  ++P+      ++D
Sbjct: 692 QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD 751

Query: 478 ALTPQKKTSKRPSSSKKADSCT------NSEGSSQPEEQLKSPMAESLDGGCSSSSEDQG 531
               Q K  K  +    + S T      +S+  SQ EE+   P+        S S    G
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD-SAKPSQSFPPTG 810

Query: 532 ERVRQLSGQ------STSSDTTYKGGASEKAGSSPAQGAQN-EPPRLNASPAAREEATSP 584
           E+V     +      S S   ++ G +SE  G       Q  E P+     A  + +  P
Sbjct: 811 EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK----KAQTKMSPKP 866

Query: 585 GAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGA 644
            AK MP  S   P     T G  V     +    KP  Q +    +  + T  P S    
Sbjct: 867 DAKPMPKGSP-TPPGPRPTAGQTVPTPQQS---PKPQEQSRRFSLNLGSITDAPKSQ--- 919

Query: 645 KETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGS 704
                 + PQ    G     G       SN          HS +GPG   +  P+ S   
Sbjct: 920 -----PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPP 974

Query: 705 LRYSYKDSFGSAVPRNVSGFP 725
                  S G A P      P
Sbjct: 975 TSQGPPKSTGQAPPAPAKSIP 995



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 85/377 (22%), Positives = 138/377 (36%), Gaps = 59/377 (15%)

Query: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560
            G LAP  +    + +   VT +       P+    S KK   P   ++K  + ++PPP  
Sbjct: 648  GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707

Query: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVE--PQEPEIKLKYAT 1618
             QP     GS   + K   +     +  P  +P     +   P+ +  P++P++ +K  T
Sbjct: 708  KQPTL--HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM-VKPTT 764

Query: 1619 QPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPP---- 1674
              +  + A  K   P   V ++             EE+ T  ++    + S + PP    
Sbjct: 765  DLVSSSSATTKPDIPSSKVQSQA------------EEKTTPPLKTDSAKPSQSFPPTGEK 812

Query: 1675 -SSTESKALP---ASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYA 1730
             S  +SKA+P   + S ++  P  +  S     V  +  K    +    +     P+  A
Sbjct: 813  VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKM----SPKPDA 868

Query: 1731 ATLPK---NPPPKRATEMQS----------KVKVRHKSASNGSKTDTEEEEEQQQQQKEQ 1777
              +PK    PP  R T  Q+          + + R  S + GS TD  + +    Q+   
Sbjct: 869  KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928

Query: 1778 RSLAAHPR--FKRRHRSEDCGG--GPRSLS-RGLPCKKAATEGSSEKTVLDSKPSVPTTS 1832
              L       F +        G  GP S S  G P K+A              PS P TS
Sbjct: 929  GKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA------------PSQPPTS 976

Query: 1833 EGGPELELQIPELPLDS 1849
            +G P+   Q P  P  S
Sbjct: 977  QGPPKSTGQAPPAPAKS 993



 Score = 35.0 bits (79), Expect = 0.72
 Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 15/170 (8%)

Query: 438  FGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTP-----QKKTSKRPSSS 492
            FGL     K +TD      S+L T +  L NT++  L  +A  P     + + S RPSS 
Sbjct: 4243 FGLR----KNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSV 4298

Query: 493  KKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLS-GQSTSSDTTYKGG 551
               D     + SS    +LK+  AE+LD   S +S     +   L   QS          
Sbjct: 4299 YGLDLSIKRDSSSS-SLRLKAQEAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQN 4357

Query: 552  ASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNE 601
            + E++  SP      +P  +  + A      S   +D   SS   P+V +
Sbjct: 4358 SEEESPLSPV----GQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQ 4403



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 10/76 (13%)

Query: 1530 PKGYFPSGKK-------KGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQ 1582
            P    PSG         K RP    +      QPPPPPP PP  P       P P     
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP---PPPPPPPPPPLP 2428

Query: 1583 RRERRKPGAQPRKRKT 1598
                 KP   P+K+ T
Sbjct: 2429 PPTSPKPTILPKKKLT 2444



 Score = 33.1 bits (74), Expect = 2.7
 Identities = 148/729 (20%), Positives = 217/729 (29%), Gaps = 159/729 (21%)

Query: 1197 PAKSSG---PPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVML-----RLPGQEDH-SS 1247
            P K SG    PG  +Q        TD     +      P ++ L     R   +E+H SS
Sbjct: 92   PPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSS 151

Query: 1248 QNP-LIMRRRVRSFISPIPSKRQSQDV---KNSSTEDKGRLLHSSKEGADKAFNSYAHLS 1303
              P  +      S +S + +K    D+     +S E+  +     ++   K         
Sbjct: 152  MMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL 211

Query: 1304 HSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPN 1363
              Q  K IPK+      P        +++   P K K  PP  G G  ++   Q   + +
Sbjct: 212  QQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP--GTGKPIQGPTQTPQTDH 269

Query: 1364 ----IRRSASSNSAEAGGDTVTLDDILSLKSGP-------PEGGSVAVQDADIEKRKGEV 1412
                ++R AS    +   D V  + +      P       P  G    Q    EK +   
Sbjct: 270  AKLPLQRDASRPQTKQA-DIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328

Query: 1413 ASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEP------------ 1460
            A     P+     + KPL +     +  V     T+  A+ +   K P            
Sbjct: 329  AKPPAQPSG----LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384

Query: 1461 ---------PGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVP------------- 1498
                     P  +  T +Q+PG  +  P   +G   PL        P             
Sbjct: 385  QPGPKALAQPPGVGKTPAQQPGPAKP-PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443

Query: 1499 --PVGILAPEANPKAEEKENDTVTISPKQ-------------EGFPPKGYFPSGKKKGRP 1543
              P  I A +A P     +    T  P Q                PP     S K   + 
Sbjct: 444  PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503

Query: 1544 IGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQA-- 1601
             GS     +Q  P  P PQ P   +  +      K   Q+    KP AQ   +   Q   
Sbjct: 504  PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563

Query: 1602 -----VPIVEP---QEPEIKLKYATQPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAE 1653
                  P V P   Q P   L     PL  T          +HV  K      CT     
Sbjct: 564  GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL------LLHVPEKANFN-TCT----- 611

Query: 1654 EEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQGPVVTESSVMGHLVCCLCGKWAS 1713
             E QT +           P P  TE K                          LC     
Sbjct: 612  -ECQTTVC----SLCGFNPNPHLTEVKE------------------------WLCLNCQM 642

Query: 1714 YRNMGDLFGPFYPQDYAATLPKNPPPKRATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQ 1773
             R +G    P         +P +P PK  T   +      KS+    +T  +++   +Q 
Sbjct: 643  KRALGGDLAP---------VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693

Query: 1774 QK------------EQRSLAAHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEGSSEKT- 1820
                          +Q +L   P  K +   E       SLS+  P K+ +     +K  
Sbjct: 694  LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE-----ADSLSKPAPPKEPSVPSEQDKAP 748

Query: 1821 VLDSKPSVP 1829
            V D KP  P
Sbjct: 749  VADDKPKQP 757


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 298/1478 (20%), Positives = 478/1478 (32%), Gaps = 288/1478 (19%)

Query: 184  RQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSS 243
            +Q+L  SH P  + +G+P       QP    S    +    Q   G+      S+ S   
Sbjct: 84   KQELDSSHPP--KQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRS----PSTISLKE 137

Query: 244  SSSFPSPQRFSQSGQSYDGSYNVNAGS-------QYEGHNVGSNAQAYGTQSNYSYQPQS 296
            S S    +   +S         VNA S       ++   ++ S+++A   ++    + Q 
Sbjct: 138  SKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETT---KKQK 194

Query: 297  MKNFEQAKIPQGTQQGQQQQQPQQ----QQHPSQHVMQYTNAATKLPLQSQVGQYNQPEV 352
            +   EQ K P+G  +   QQQP +    QQ P +  +Q       +  Q       QPE 
Sbjct: 195  VVQKEQGK-PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQ-------QPE- 245

Query: 353  PVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRIL 412
             ++S         P     P     Q+P       PL +     Q  Q  +  G    + 
Sbjct: 246  KIKS--------QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES--VK 295

Query: 413  QLMPQLSPTPSMMPSPNSHAAGFKGFGL-EGVPEKRLTDPGLSSLSALSTQVANLPNTVQ 471
              +P  S  P   P+P    A   G    +  P K    P     S L+  +A  P TV+
Sbjct: 296  PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQP-----SGLTKPLAQQPGTVK 350

Query: 472  HMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQG 531
              +     T   K   +P    K  +     GS +P  +   P A +   G         
Sbjct: 351  PPVQPPGTT---KPPAQPLGPAKPPA--QQTGSEKPSSEQPGPKALAQPPGVG------- 398

Query: 532  ERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPL 591
                             K  A +   + P       P  L   P  +  A +PG    P+
Sbjct: 399  -----------------KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441

Query: 592  SSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHAS 651
               G  K+  +  G   +    TG  + P      SQ   PA  + PP   G  +     
Sbjct: 442  QQPGPGKIPAQQAGPGKTSAQQTGPTKPP------SQLPGPA--KPPPQQPGPAK----- 488

Query: 652  LPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKD 711
             P P+ PG       + G  ++    +  G +  S   PG T    PS+ P         
Sbjct: 489  -PPPQQPGSAKPPSQQPG--STKPPPQQPGPAKPSPQQPGSTK--PPSQQP--------- 534

Query: 712  SFGSAVPRNVSGFPQYPTGQEKG---DFTGHGERKGRNEKFPSLLQEVLQGYH------- 761
              GSA P      P  P+ Q+       TG G+        PS  Q   QG         
Sbjct: 535  --GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLC 592

Query: 762  -------HHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNE-LASRGLLNKSIGSLLE 813
                   H P++    +  E Q    SL G   PN  +++  E L     + +++G    
Sbjct: 593  NTTELLLHVPEKANFNTCTECQTTVCSLCG-FNPNPHLTEVKEWLCLNCQMKRALG---- 647

Query: 814  NPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPL 873
                G      SS  P++K   +T      K   +PQ ++ +   +  +  S   +    
Sbjct: 648  ----GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP 703

Query: 874  RQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPG---------------GLVSME 918
              +V+ P  H      A      +    P   +   +P                 +V   
Sbjct: 704  PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763

Query: 919  TKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDY 978
            T L S S    + D   SK Q+    K +      P +K +S    A P  +   +    
Sbjct: 764  TDLVSSSSATTKPDIPSSKVQSQAEEKTT------PPLKTDS----AKPSQSFPPTGEKV 813

Query: 979  GPQDSRPTP-------MRRVPGRVGGREGMRGRSPSQYHDFAEK--LKMS--PGRSRGPG 1027
             P DS+  P       +   PG     +G +   P Q  +  +K   KMS  P     P 
Sbjct: 814  SPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873

Query: 1028 GDPHHMNPHMTFSERANRSSLHTP-FSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYK 1086
            G P    P  T  +     ++ TP  SP  +  +  +  N      G       SQ    
Sbjct: 874  GSPTPPGPRPTAGQ-----TVPTPQQSPKPQEQSRRFSLN-----LGSITDAPKSQPTTP 923

Query: 1087 RQMYQQQPEEYKDWSSGSAQGVIAAA----QHRQEGPRKSPRQQQFLDRVRSPLKNDKDG 1142
            ++    +   +       A  +I+ A     H Q GP    +Q        +P  + +  
Sbjct: 924  QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ--------APAPS-QPP 974

Query: 1143 MMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSG 1202
               GPP  T   P A             P K + +K      +E+    + +  P     
Sbjct: 975  TSQGPPKSTGQAPPA-------------PAKSIPVK------KETKAPAAEKLEPKAEQA 1015

Query: 1203 PPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFIS 1262
            P    ++    PP   D   L    Q +   + + + P  E   S  PL          +
Sbjct: 1016 PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE---STCPLCK--------T 1064

Query: 1263 PIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQ---------------- 1306
             +    +     N+ TE K ++ +         FN   HL+  Q                
Sbjct: 1065 ELNIGSKDPPNFNTCTECKNQVCNLC------GFNPTPHLTEIQEWLCLNCQTQRAISGQ 1118

Query: 1307 --DIKSIPKRDSSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNI 1364
              DI+ +P   S      P +   P  T +S  KT + P  K         + K     +
Sbjct: 1119 LGDIRKMPPAPS-----GPKASPMPVPTESSSQKTAVPPQVK---------LVKKQEQEV 1164

Query: 1365 RRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQEL 1424
            +  A     E   +T++++ I      PP      +   D ++ + ++  D  S     L
Sbjct: 1165 KTEAEKVILEKVKETLSMEKI------PP------MVTTDQKQEESKLEKDKAS----AL 1208

Query: 1425 HVEKPLPRS-----SEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQK-----PGS 1474
              +KPLP        EE   S + K   E    T    K  P A TS   ++        
Sbjct: 1209 QEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQ 1268

Query: 1475 NQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYF 1534
             Q   +   G  AP    + K         P   P++  KE+D  T + K++  PP    
Sbjct: 1269 VQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAK 1328

Query: 1535 PSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSAD 1572
            P   + G+       +K+  +      Q P+ P+G +D
Sbjct: 1329 PDQVEPGKE----KTEKEDDKSDTSSSQQPKSPQGLSD 1362



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 118/535 (22%), Positives = 187/535 (34%), Gaps = 97/535 (18%)

Query: 1198 AKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLR--LPGQEDHSSQNPLIMRR 1255
            +KSS  P  +S K+   P +     L++A +  KP  ++ +  L G     ++ P     
Sbjct: 673  SKSSPQPQQTSPKKDAAPKQD----LSKAPEPKKPPPLVKQPTLHGSPSAKAKQP----P 724

Query: 1256 RVRSFISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRD 1315
               S   P P K  S      S +DK  +    K    K       L  S    + P   
Sbjct: 725  EADSLSKPAPPKEPSVP----SEQDKAPVA-DDKPKQPKMVKPTTDLVSSSSATTKPDIP 779

Query: 1316 SSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEA 1375
            SSK     + +  P +   S   ++  PP   +       V    S  I R AS +    
Sbjct: 780  SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK-------VSPFDSKAIPRPASDSK--- 829

Query: 1376 GGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSE 1435
                     I+S      E       D   +K + + A   +SP        KP+P+ S 
Sbjct: 830  ---------IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA----KPMPKGSP 876

Query: 1436 EWRGSVDDKVKTETHAETVTAGKEPP-------------GAMTSTTSQKPGSNQGRPDGS 1482
               G         T  +TV   ++ P             G++T     +P + Q    G 
Sbjct: 877  TPPGP------RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930

Query: 1483 LGGTAPLIFPDSKN-VPPVGILAP--EANPKAEEKENDTVTISPKQEGFPPK--GYFPSG 1537
            L G    IF  + N +   G   P  ++ P A  K+    +  P  +G PPK  G  P  
Sbjct: 931  LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG-PPKSTGQAPPA 989

Query: 1538 KKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRK 1597
              K  P+    K    ++  P   Q P +     + +P P K     + +   A+P+   
Sbjct: 990  PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIK-----DSKSLTAEPQ--- 1041

Query: 1598 TKQAVPIVEPQEPEIKLKYATQPLDKTDAK-NKSFYPYIHVVNKCELGAVCTIINAE--- 1653
             K  +P    + P+ +   +T PL KT+        P  +   +C+   VC +       
Sbjct: 1042 -KAVLPTKLEKSPKPE---STCPLCKTELNIGSKDPPNFNTCTECK-NQVCNLCGFNPTP 1096

Query: 1654 --EEEQTKLVRGRKGQRSLT--------PPPSSTESKALPASSFMLQGPVVTESS 1698
               E Q  L    + QR+++         PP+ +  KA P        PV TESS
Sbjct: 1097 HLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPM-------PVPTESS 1144



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 150/681 (22%), Positives = 216/681 (31%), Gaps = 86/681 (12%)

Query: 96  KDPVTT-GTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQ 154
           K PV   GT +PP + P GP +   PP   +   +  SE    +  AQ  G+G     Q 
Sbjct: 350 KPPVQPPGTTKPPAQ-PLGPAK---PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405

Query: 155 DYTGPFSPGSAQYQQQASSQQQ---QQQVQQLRQQLYQSHQPLP-----QATGQPASSSS 206
              GP  P + Q        QQ   Q   +          QP P     Q  G   +S+ 
Sbjct: 406 ---GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462

Query: 207 HLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSS-----SSSFPSPQRFSQSGQSYD 261
              P + PS LP  A     + G      Q   S+        S+ P PQ+   +  S  
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522

Query: 262 GSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQ 321
              +    SQ  G    S  Q    + +     + +      K  Q        +QP  Q
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582

Query: 322 QHPSQ--HVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQS 379
             P     +   T     +P ++      + +  V S   F        NP+P  + V+ 
Sbjct: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGF--------NPNPHLTEVKE 634

Query: 380 PSC----------------SSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTP- 422
             C                 S+P P ++T         S    S  +  Q  P+    P 
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTT---SAVSKSSPQPQQTSPKKDAAPK 691

Query: 423 ---SMMPSPNSHAAGFKGFGLEGVPE-KRLTDPGLSSLSALST-QVANLPNTVQHMLLSD 477
              S  P P       K   L G P  K    P   SLS  +  +  ++P+      ++D
Sbjct: 692 QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD 751

Query: 478 ALTPQKKTSKRPSSSKKADSCT------NSEGSSQPEEQLKSPMAESLDGGCSSSSEDQG 531
               Q K  K  +    + S T      +S+  SQ EE+   P+        S S    G
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD-SAKPSQSFPPTG 810

Query: 532 ERVRQLSGQ------STSSDTTYKGGASEKAGSSPAQGAQN-EPPRLNASPAAREEATSP 584
           E+V     +      S S   ++ G +SE  G       Q  E P+     A  + +  P
Sbjct: 811 EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK----KAQTKMSPKP 866

Query: 585 GAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGA 644
            AK MP  S   P     T G  V     +    KP  Q +    +  + T  P S    
Sbjct: 867 DAKPMPKGSP-TPPGPRPTAGQTVPTPQQS---PKPQEQSRRFSLNLGSITDAPKSQ--- 919

Query: 645 KETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGS 704
                 + PQ    G     G       SN          HS +GPG   +  P+ S   
Sbjct: 920 -----PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPP 974

Query: 705 LRYSYKDSFGSAVPRNVSGFP 725
                  S G A P      P
Sbjct: 975 TSQGPPKSTGQAPPAPAKSIP 995



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 85/377 (22%), Positives = 138/377 (36%), Gaps = 59/377 (15%)

Query: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560
            G LAP  +    + +   VT +       P+    S KK   P   ++K  + ++PPP  
Sbjct: 648  GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707

Query: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVE--PQEPEIKLKYAT 1618
             QP     GS   + K   +     +  P  +P     +   P+ +  P++P++ +K  T
Sbjct: 708  KQPTL--HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM-VKPTT 764

Query: 1619 QPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPP---- 1674
              +  + A  K   P   V ++             EE+ T  ++    + S + PP    
Sbjct: 765  DLVSSSSATTKPDIPSSKVQSQA------------EEKTTPPLKTDSAKPSQSFPPTGEK 812

Query: 1675 -SSTESKALP---ASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYA 1730
             S  +SKA+P   + S ++  P  +  S     V  +  K    +    +     P+  A
Sbjct: 813  VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKM----SPKPDA 868

Query: 1731 ATLPK---NPPPKRATEMQS----------KVKVRHKSASNGSKTDTEEEEEQQQQQKEQ 1777
              +PK    PP  R T  Q+          + + R  S + GS TD  + +    Q+   
Sbjct: 869  KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928

Query: 1778 RSLAAHPR--FKRRHRSEDCGG--GPRSLS-RGLPCKKAATEGSSEKTVLDSKPSVPTTS 1832
              L       F +        G  GP S S  G P K+A              PS P TS
Sbjct: 929  GKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA------------PSQPPTS 976

Query: 1833 EGGPELELQIPELPLDS 1849
            +G P+   Q P  P  S
Sbjct: 977  QGPPKSTGQAPPAPAKS 993



 Score = 35.0 bits (79), Expect = 0.72
 Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 15/170 (8%)

Query: 438  FGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTP-----QKKTSKRPSSS 492
            FGL     K +TD      S+L T +  L NT++  L  +A  P     + + S RPSS 
Sbjct: 4243 FGLR----KNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSV 4298

Query: 493  KKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLS-GQSTSSDTTYKGG 551
               D     + SS    +LK+  AE+LD   S +S     +   L   QS          
Sbjct: 4299 YGLDLSIKRDSSSS-SLRLKAQEAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQN 4357

Query: 552  ASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNE 601
            + E++  SP      +P  +  + A      S   +D   SS   P+V +
Sbjct: 4358 SEEESPLSPV----GQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQ 4403



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 10/76 (13%)

Query: 1530 PKGYFPSGKK-------KGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQ 1582
            P    PSG         K RP    +      QPPPPPP PP  P       P P     
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP---PPPPPPPPPPLP 2428

Query: 1583 RRERRKPGAQPRKRKT 1598
                 KP   P+K+ T
Sbjct: 2429 PPTSPKPTILPKKKLT 2444



 Score = 33.1 bits (74), Expect = 2.7
 Identities = 148/729 (20%), Positives = 217/729 (29%), Gaps = 159/729 (21%)

Query: 1197 PAKSSG---PPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVML-----RLPGQEDH-SS 1247
            P K SG    PG  +Q        TD     +      P ++ L     R   +E+H SS
Sbjct: 92   PPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSS 151

Query: 1248 QNP-LIMRRRVRSFISPIPSKRQSQDV---KNSSTEDKGRLLHSSKEGADKAFNSYAHLS 1303
              P  +      S +S + +K    D+     +S E+  +     ++   K         
Sbjct: 152  MMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL 211

Query: 1304 HSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPN 1363
              Q  K IPK+      P        +++   P K K  PP  G G  ++   Q   + +
Sbjct: 212  QQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP--GTGKPIQGPTQTPQTDH 269

Query: 1364 ----IRRSASSNSAEAGGDTVTLDDILSLKSGP-------PEGGSVAVQDADIEKRKGEV 1412
                ++R AS    +   D V  + +      P       P  G    Q    EK +   
Sbjct: 270  AKLPLQRDASRPQTKQA-DIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328

Query: 1413 ASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEP------------ 1460
            A     P+     + KPL +     +  V     T+  A+ +   K P            
Sbjct: 329  AKPPAQPSG----LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384

Query: 1461 ---------PGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVP------------- 1498
                     P  +  T +Q+PG  +  P   +G   PL        P             
Sbjct: 385  QPGPKALAQPPGVGKTPAQQPGPAKP-PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443

Query: 1499 --PVGILAPEANPKAEEKENDTVTISPKQ-------------EGFPPKGYFPSGKKKGRP 1543
              P  I A +A P     +    T  P Q                PP     S K   + 
Sbjct: 444  PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503

Query: 1544 IGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQA-- 1601
             GS     +Q  P  P PQ P   +  +      K   Q+    KP AQ   +   Q   
Sbjct: 504  PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563

Query: 1602 -----VPIVEP---QEPEIKLKYATQPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAE 1653
                  P V P   Q P   L     PL  T          +HV  K      CT     
Sbjct: 564  GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL------LLHVPEKANFN-TCT----- 611

Query: 1654 EEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQGPVVTESSVMGHLVCCLCGKWAS 1713
             E QT +           P P  TE K                          LC     
Sbjct: 612  -ECQTTVC----SLCGFNPNPHLTEVKE------------------------WLCLNCQM 642

Query: 1714 YRNMGDLFGPFYPQDYAATLPKNPPPKRATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQ 1773
             R +G    P         +P +P PK  T   +      KS+    +T  +++   +Q 
Sbjct: 643  KRALGGDLAP---------VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693

Query: 1774 QK------------EQRSLAAHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEGSSEKT- 1820
                          +Q +L   P  K +   E       SLS+  P K+ +     +K  
Sbjct: 694  LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE-----ADSLSKPAPPKEPSVPSEQDKAP 748

Query: 1821 VLDSKPSVP 1829
            V D KP  P
Sbjct: 749  VADDKPKQP 757


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 282/1363 (20%), Positives = 444/1363 (32%), Gaps = 253/1363 (18%)

Query: 189  QSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASS------- 241
            +SH   PQ  G+  SSS      +       S +  +++  +       S SS       
Sbjct: 712  RSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS 771

Query: 242  ------SSSSSFPSPQRFSQSG--QSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQ 293
                  S S S P P++ SQ+   +S  GS    A S+       S++     Q + +  
Sbjct: 772  RLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS 831

Query: 294  PQSMKNFE-QAKIPQGTQQGQ--------QQQQPQQQQHPSQHVMQYTNAATKLPLQSQV 344
             QS  +     K+  GT   Q         +Q    Q+             ++ P +   
Sbjct: 832  RQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSC 891

Query: 345  GQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSP-----SCSSTPSPLMQTGENLQCG 399
               + P V   +P +  Q+ S  S+P P    + SP     S SS+PSP   T       
Sbjct: 892  SGSSPPRVKSSTPPR--QSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR 949

Query: 400  QGSVPMGSR--NRIL-----------------QLMPQLSPTPSMMPSPNSHAAGFKGFGL 440
              SV   S   +R+L                 +  P+ S + S+ P P   A    G  L
Sbjct: 950  SRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSL 1009

Query: 441  EGVPE-------------------------KRLTDPGLSSLSALSTQVANLPNTVQHMLL 475
             G                            K  T PG S     S Q+     T      
Sbjct: 1010 SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHR- 1068

Query: 476  SDALTPQKKTSKRPSSSKKADSCTNSEG----SSQPEEQL--KSPMAESLDGGCSSSSED 529
            SD  +P+ + S   S S ++ S T+ +G    SS P  +L  +SP+ +      +S    
Sbjct: 1069 SDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128

Query: 530  QGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNE-----PPR--LNASPAAREEAT 582
             G    Q   QS SS        S   G S  + A+++     PP+    ASP  +++  
Sbjct: 1129 SGMSPEQSRFQSDSSSYPTVDSNS-LLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187

Query: 583  SP-GAKDMPLSS-----------------DGNPKVNEKTVGVIVSRE-----AMTGRVEK 619
            SP   +D P SS                   +P+  E+   +  S +      +  + E+
Sbjct: 1188 SPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEE 1247

Query: 620  PGGQ------------DKGSQEDDPAATQRPPSNGGAKET-SHASLPQPEPPGGGGSKGN 666
            P GQ               + E  P   +RP  +    ++ S ASL   E P    S G 
Sbjct: 1248 PAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGG 1307

Query: 667  KNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSG--- 723
             +   +  H    N     ++ G     R       G L       F S V  +++G   
Sbjct: 1308 PHF--SPEHKELSNSPLRENSFGSPLEFRNS-----GPLGTEMNTGFSSEVKEDLNGPFL 1360

Query: 724  -----FPQYPTGQEKGDFTGHG---------ERKGRNEKFPSLLQEVLQGYHHHPDRRYS 769
                  P     ++    +GH          E+ G +    S+   VL      P R  S
Sbjct: 1361 NQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSN-QSISSPVLDAVPRTPSRERS 1419

Query: 770  RSTQEHQGMAGSLEGTTRPNVLVSQT-----NELASRGLLNKSIGSLLENPHWGPWERKS 824
             S    +   G     +R +   S       +   SR  L+ S   + + P      R  
Sbjct: 1420 SSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE 1479

Query: 825  SSTAPEMKQINLTDYPIPR-----KFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRD 879
              ++PE K +  T  P  R     +   +  +   E  GS S         +PL Q  R 
Sbjct: 1480 CDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRS 1539

Query: 880  PGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLK--SQSGQIKEEDFEQSK 937
              +  L    + +   R        S+S   P       T L+  S+SG   E D   SK
Sbjct: 1540 GSSQELDVKPSASPQER--------SESDSSPDSKAKTRTPLRQRSRSGSSPEVD---SK 1588

Query: 938  SQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGG 997
            S+ S    +SG     P +K +     A+P A    S SD  P+   P P R +P R   
Sbjct: 1589 SRLSPRRSRSGSS---PEVKDKP---RAAPRA---QSGSDSSPEPKAPAP-RALPRRSRS 1638

Query: 998  REGMRGRSPS-QYHDFAEKLKMSPGRSR----GPGGDPH--------------HMNPHMT 1038
                +GR PS +     E     P +SR    G    P                 +P +T
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698

Query: 1039 FSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYK 1098
               R +R S     SP + +     H   R+ +   P     S+   +R+          
Sbjct: 1699 RKARLSRRSRSASSSPETRSRTPPRHR--RSPSVSSPEPAEKSRSSRRRR---------- 1746

Query: 1099 DWSSGSAQGVIAAAQHRQEGPR----KSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHD 1154
              S+ S +    + + R   P+    +  R +   ++ R+  + D+ G            
Sbjct: 1747 --SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804

Query: 1155 PSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGP 1214
             S     R      G  ++       S   QES    SR+    +S  PP    + R   
Sbjct: 1805 RSRSRVTRRRRGGSGYHSR-------SPARQESSRTSSRRRR-GRSRTPPTSRKRSR--- 1853

Query: 1215 PHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVK 1274
               T       +   + P +            S+ PLI RRR RS  SP+  +R      
Sbjct: 1854 -SRTSPAPWKRSRSRASPAT-------HRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTS 1905

Query: 1275 NSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLP----SPDSRNCPA 1330
             +    + R    S+  +                 +  +R  S+  P       SR  P 
Sbjct: 1906 VTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV 1965

Query: 1331 VTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSA 1373
                S ++T  +  R+ R           TSP  RR + S ++
Sbjct: 1966 TRRRSRSRTSPITRRRSRSR---------TSPVTRRRSRSRTS 1999



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 231/1117 (20%), Positives = 376/1117 (33%), Gaps = 137/1117 (12%)

Query: 482  QKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQS 541
            + +TS+R S S  +     S  SS+    L SP          S ++ +    R LSG S
Sbjct: 733  KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP---------RSKAKSRLSLRRSLSGSS 783

Query: 542  -TSSDTTYKGGASEKAGSSPAQGAQNEPP---RLNASPAAREEATSPGAKDMPLSSDGNP 597
                  +       ++GSS  +     PP   R ++SP  ++++ +P ++    SS  +P
Sbjct: 784  PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP-SRQSHSSSSPHP 842

Query: 598  KVNEKT---VGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQ 654
            KV   T    G I S +A    V  P  +       DP    R PS      +S   +  
Sbjct: 843  KVKSGTPPRQGSITSPQANEQSV-TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKS 901

Query: 655  PEPPGGGGSKGNKNGDN-NSNHNGEGNGQSGHSAAGPG-FTSRTEP----SKSPGS---- 704
              PP    S+ +       +  +      SG S+  P   TSRT P    S SP S    
Sbjct: 902  STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVES 961

Query: 705  ---LRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYH 761
                RYS+    GS+ P         P     G  + + + K +    PSL         
Sbjct: 962  RLLPRYSHS---GSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQ 1018

Query: 762  HHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWE 821
                    +S      +   ++ +T P       + L  +G    S             +
Sbjct: 1019 EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP------------D 1066

Query: 822  RKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPG 881
             +S +++PE++Q +     +  K +  P+         ++E    +   SP+RQ   D G
Sbjct: 1067 HRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTE----LASRSPIRQ---DRG 1119

Query: 882  AHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQAS 941
              S   M          R     S    +    +  +++L++   + K     Q  + AS
Sbjct: 1120 EFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATAS 1179

Query: 942  FNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGM 1001
                       PP  K +      SP        S    +D+  TP R   G     E  
Sbjct: 1180 -----------PPRQKDK-----FSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETK 1223

Query: 1002 RGRSPSQYHDFAEKLKMSPGRSRGPGGD-PHHMNPHMTFSERAN-RSSLHTPFSP----- 1054
               S        E+L     +S  P G    H++  +     +N  SS      P     
Sbjct: 1224 EQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLT 1283

Query: 1055 ----NSETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIA 1110
                 S+    A    + A ++G P        H+  +  +      ++ S GS      
Sbjct: 1284 LDQSQSQASLEAVEVPSMASSWGGP--------HFSPEHKELSNSPLRENSFGS------ 1329

Query: 1111 AAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCL--MSSD 1168
              + R  GP  +     F   V+  L       +   P     + S + +G     +S D
Sbjct: 1330 PLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPD 1389

Query: 1169 GLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPP-------HETDGH 1221
             +   GM     +Q +     D   +T P++       S + + G P             
Sbjct: 1390 AVEKAGMS---SNQSISSPVLDAVPRT-PSRERSSSASSPEMKDGLPRTPSRRSRSGSSP 1445

Query: 1222 GLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISP--IPSKRQSQDVKNSSTE 1279
            GL + + +    S+    PG +D   + P   R    S   P  +P   + +    SS E
Sbjct: 1446 GLRDGSGTPSRHSLSGSSPGMKD-IPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504

Query: 1280 DKGRLLHSSKE--GADKAFN--SYAHLSHSQDIKSIPKRD-SSKDLPSPDSRNCPAVTLT 1334
               + L   +E  G++ + +  + A     Q  +S   ++   K   SP  R+    +  
Sbjct: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPD 1564

Query: 1335 SPAKTKI-LPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTVTLDDILSLKSGPP 1393
            S AKT+  L  R   G   E   +   SP  RRS S +S E            S     P
Sbjct: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSP--RRSRSGSSPEVKDKPRAAPRAQSGSDSSP 1622

Query: 1394 EGGSVAVQDADIEKRKGEVASDL-VSP---ANQELHVEKPLPRSSEEWRGSVDDKVKTET 1449
            E  + A +      R G  +     SP   ++ E   E P P+S    RGS        +
Sbjct: 1623 EPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP-PKSRTARRGS-------RS 1674

Query: 1450 HAETVTAGKEPPGAMTSTTSQKPG-----SNQGRPDGSLGGTAPLIFPDSKNVPPVGILA 1504
              E  T  + PP   +S +S +       S + R   S   T     P  +  P V   +
Sbjct: 1675 SPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS--S 1732

Query: 1505 PEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKG 1541
            PE   K+          SP+ +    +G  PS K +G
Sbjct: 1733 PEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRG 1769



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 223/1166 (19%), Positives = 391/1166 (33%), Gaps = 161/1166 (13%)

Query: 476  SDALTPQKKTSKRPSSSKKADSCTN---SEGSSQPE---EQLKSPMAESLDGGCSSSSED 529
            S + TPQ++     SS +K  S T+   S  +S PE    ++ S  + SL    S +   
Sbjct: 713  SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772

Query: 530  QGERVRQLSGQSTS-SDTTYKGGASEKAGSSPAQGAQNEPPRLN---ASPAAREEATSPG 585
               R R LSG S      +       ++GSS  +     PPR +   +SP  ++++ +P 
Sbjct: 773  LSLR-RSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP- 830

Query: 586  AKDMPLSSDGNPKVNEKTV---GVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNG 642
            ++    SS  +PKV   T    G I S +A    V  P  +       DP    R PS  
Sbjct: 831  SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVT-PQRRSCFESSPDPELKSRTPSRH 889

Query: 643  GAKETSHASLPQPEPPGGGGSKGNKNGDN-NSNHNGEGNGQSGHSAAGPG-FTSRTEP-- 698
                +S   +    PP    S+ +       +  +      SG S+  P   TSRT P  
Sbjct: 890  SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR 949

Query: 699  --SKSPGSL-------RYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKF 749
              S SP S        RYS+    GS+ P         P     G  + + + K +    
Sbjct: 950  SRSVSPCSNVESRLLPRYSHS---GSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPG 1006

Query: 750  PSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIG 809
            PSL                 +S      +   ++ +T P       + L  +G    S  
Sbjct: 1007 PSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP- 1065

Query: 810  SLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICD 869
                       + +S +++PE++Q +     +  K +  P+         ++E    +  
Sbjct: 1066 -----------DHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTE----LAS 1110

Query: 870  ISPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIK 929
             SP+RQ   D G  S   M          R     S    +    +  +++L++   + K
Sbjct: 1111 RSPIRQ---DRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEK 1167

Query: 930  EEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMR 989
                 Q  + AS           PP  K +      SP        S    +D+  TP R
Sbjct: 1168 MALPPQEDATAS-----------PPRQKDKF-----SPFPVQDRPESSLVFKDTLRTPPR 1211

Query: 990  RVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDP-HHMNPHMTFSERAN-RSS 1047
               G     E     S        E+L     +S  P G    H++  +     +N  SS
Sbjct: 1212 ERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESS 1271

Query: 1048 LHTPFSP---------NSETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYK 1098
                  P          S+    A    + A ++G P        H+  +  +      +
Sbjct: 1272 PEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGP--------HFSPEHKELSNSPLR 1323

Query: 1099 DWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQ 1158
            + S GS        + R  GP  +     F   V+  L       +   P     + S +
Sbjct: 1324 ENSFGSP------LEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTR 1377

Query: 1159 EAGRCL--MSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPH 1216
             +G     +S D +   GM     +Q +     D   +T P++       S + + G P 
Sbjct: 1378 SSGHSSSELSPDAVEKAGMS---SNQSISSPVLDAVPRT-PSRERSSSASSPEMKDGLPR 1433

Query: 1217 ETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVKNS 1276
                   + ++   + GS     P +   S  +P          +  IP           
Sbjct: 1434 TPSRRSRSGSSPGLRDGS---GTPSRHSLSGSSP---------GMKDIPR---------- 1471

Query: 1277 STEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTSP 1336
             T  +GR                +    S + K++P+       P P SR+  +  L + 
Sbjct: 1472 -TPSRGR----------------SECDSSPEPKALPQT------PRPRSRSPSSPELNN- 1507

Query: 1337 AKTKILPPRKGRGLKLEAIVQKITS--PNIRRSASSNSAEAGGDTVTLDDILSLKSGPPE 1394
               K L P++ R     ++ QK  +  P  +RS S +S E            S     P+
Sbjct: 1508 ---KCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPD 1564

Query: 1395 GGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETV 1454
              S A     + +R    +S  V  +   L   +    SS E +       + ++ +++ 
Sbjct: 1565 --SKAKTRTPLRQRSRSGSSPEVD-SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSS 1621

Query: 1455 TAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEK 1514
               K P        S+   S++GR     G ++    P+    PP    A   +  + E 
Sbjct: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH---PPKSRTARRGSRSSPEP 1678

Query: 1515 ENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGE 1574
            +  + T   ++            +   R   + +  + + + PP   + P +        
Sbjct: 1679 KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV------SS 1732

Query: 1575 PKPKKQRQRRERRKPGAQPRKRKTKQ 1600
            P+P ++ +   RR+  + PR + T +
Sbjct: 1733 PEPAEKSRSSRRRRSASSPRTKTTSR 1758



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 67/308 (21%), Positives = 107/308 (34%), Gaps = 61/308 (19%)

Query: 1549 KQKKQQQPPPPPPQPPQ-IPEGSADGEPKPKKQRQR----RERRKPGAQPRKRKTKQAVP 1603
            + ++ +QP P PP+P   + E S+   P PK+++++    R RR   + PR+ + K +  
Sbjct: 156  RAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK 215

Query: 1604 IVEPQEPEIKLKYATQPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRG 1663
                 E E K +    P  K+  K+K                                + 
Sbjct: 216  KKHRSESESKKRKHRSPTPKSKRKSKD-------------------------------KK 244

Query: 1664 RKGQRSLTPPPSST---ESKALPASSFMLQGPVVTESSVMGHLVCCLCGKWAS----YRN 1716
            RK  RS TP P S     S +  ++S        + S+        L G+  S     R 
Sbjct: 245  RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304

Query: 1717 MGDLFGPFYPQDYAATLPKNPPPKRATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKE 1776
             GD   PF      +T   + P     +  S  + + K     S T      E+     E
Sbjct: 305  EGD--APFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPE 362

Query: 1777 QRSLAAHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGP 1836
                A  P    RH     GG P+ L         AT   S++ V     + PT     P
Sbjct: 363  PP--APTPLLAERH-----GGSPQPL---------ATTPLSQEPVNPPSEASPTRDRSPP 406

Query: 1837 ELELQIPE 1844
            +   ++P+
Sbjct: 407  KSPEKLPQ 414



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 86/421 (20%), Positives = 150/421 (35%), Gaps = 72/421 (17%)

Query: 1191 LSRQTSP-----AKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDH 1245
            +S +TSP     A+S  PP   SQ R      T     + +++  +  S  L  P Q+  
Sbjct: 2393 VSGRTSPPLLDRARSRTPPSAPSQSRM-----TSERAPSPSSRMGQAPSQSLLPPAQDQP 2447

Query: 1246 SSQNPLIMRRRVRSFISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHS 1305
             S  P     + R  I+      Q+  V  S +   G +  ++    D            
Sbjct: 2448 RSPVPSAFSDQSRCLIA------QTTPVAGSQSLSSGAVATTTSSAGDH----------- 2490

Query: 1306 QDIKSIPKRDSSKDLPSPDSRNCPAVT-LTSPAKTKILPPRKGRGLKLEAIVQKITSPNI 1364
              + S+P    +  +P  D    PA T    P+    L P K R  +  +     +S + 
Sbjct: 2491 NGMLSVP----APGVPHSDVGEPPASTGAQQPSALAALQPAKER--RSSSSSSSSSSSSS 2544

Query: 1365 RRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQEL 1424
              S+SS+S+ + G +          S   EG S+ VQ     KR   V S   +P     
Sbjct: 2545 SSSSSSSSSSSSGSS----------SSDSEGSSLPVQPEVALKR---VPSPTPAPKEAVR 2591

Query: 1425 HVEKPLPRSSEEWR---GSVDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDG 1481
                P P  ++  R    S      + + + + ++      + +S++S    S+   P  
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651

Query: 1482 SLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKG 1541
            +  G   L  P S   PP G     +  K  +   D+ ++S          Y P      
Sbjct: 2652 AKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLS----------YSP------ 2695

Query: 1542 RPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRK-PGAQPRKRKTKQ 1600
                 V +++   QP P   Q      GS  G+    +    + RR+ P  +P + ++ +
Sbjct: 2696 -----VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750

Query: 1601 A 1601
            +
Sbjct: 2751 S 2751



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 89/411 (21%), Positives = 130/411 (31%), Gaps = 108/411 (26%)

Query: 336  TKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGEN 395
            T  PL  +      P  P +S M   +       PSP++ + Q+PS S  P    Q    
Sbjct: 2397 TSPPLLDRARSRTPPSAPSQSRMTSERA------PSPSSRMGQAPSQSLLPPAQDQP--- 2447

Query: 396  LQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAA----------GFKGFGLEGVPE 445
                +  VP    ++   L+ Q +P        +   A          G       GVP 
Sbjct: 2448 ----RSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPH 2503

Query: 446  KRLTDP----GLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNS 501
              + +P    G    SAL+               S + +    +S   SSS    S ++S
Sbjct: 2504 SDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS 2563

Query: 502  EGSS---QPEEQLK---SPM-----------------------AESLDGGCSSSSEDQGE 532
            EGSS   QPE  LK   SP                        + S     SSSS     
Sbjct: 2564 EGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSS 2623

Query: 533  RVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPL- 591
                 S  S+SS ++    +S  +  SPA+                     PG + +P  
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSPSPAK---------------------PGPQALPKP 2662

Query: 592  SSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHAS 651
            +S   P   E        R + + R      +D  S    P   +RP             
Sbjct: 2663 ASPKKPPPGE--------RRSRSPRKPIDSLRDSRSLSYSPVERRRPS------------ 2702

Query: 652  LPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSP 702
             PQP P         ++  ++S+  G   GQ G S +      R  PS  P
Sbjct: 2703 -PQPSP---------RDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRP 2743



 Score = 38.9 bits (89), Expect = 0.050
 Identities = 96/467 (20%), Positives = 158/467 (33%), Gaps = 89/467 (19%)

Query: 1153 HDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWD-----LSRQTSPAKSSGPPGMS 1207
            H+   +   RCL   + +  +G E     Q++QE         L +  +P      PG  
Sbjct: 60   HERKRRVELRCLELEEMMEEQGYE----EQQIQEKVATFRLMLLEKDVNPGGKEETPGQR 115

Query: 1208 SQKRYGPPHETDGHGLAEATQ--SSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIP 1265
                   P  T+ H LAE  +  + +  +         D SS +P   +RR R    P P
Sbjct: 116  -------PAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDP---QRRAREAKQPAP 165

Query: 1266 SKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDS 1325
               +   +   S+  +     + K+   K        S S   +   K+ S K     +S
Sbjct: 166  EPPKPYSLVRESSSSRSP---TPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222

Query: 1326 RNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTVTLDD- 1384
             +      +   K+K    RK +  K +       +P  RR+  S SA++   + T    
Sbjct: 223  ESKKRKHRSPTPKSK----RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278

Query: 1385 -----------ILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRS 1433
                        L+ +S  P  G     DA   +  G  ++    P++ E   ++P   S
Sbjct: 279  SRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE-PGTTSTQ--RPSSPETATKQP---S 332

Query: 1434 SEEWRGSVDDKVKTETHA----ETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPL 1489
            S       D K K+ T      E  + G EPP A T   +++ G          G   PL
Sbjct: 333  SPYEDKDKDKKEKSATRPSPSPERSSTGPEPP-APTPLLAERHG----------GSPQPL 381

Query: 1490 IFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNK 1549
                               P ++E  N     SP ++  PPK    S +K          
Sbjct: 382  A----------------TTPLSQEPVNPPSEASPTRDRSPPK----SPEKL--------P 413

Query: 1550 QKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKR 1596
            Q    +  PP PQP ++   ++     PK        R+  + P  +
Sbjct: 414  QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSK 460



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 270/1367 (19%), Positives = 445/1367 (32%), Gaps = 202/1367 (14%)

Query: 353  PVRSPMQFHQNFSPISNP-SPAASVVQSPSCSS--TPSPLMQTGENLQCGQGSVPMGSRN 409
            P +SP +  Q+ S  S+P SP  + V   + SS  +P P    G + +           +
Sbjct: 405  PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSH 464

Query: 410  RILQLMPQLSPTPSM-MPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPN 468
               +     S TPS  M    S A   +G      P KR      S     S        
Sbjct: 465  GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524

Query: 469  TVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSS-- 526
            +        + +PQ     RP  S+  +  T   G S+   + +S        G S S  
Sbjct: 525  SRSPQRRGRSRSPQ-----RPGWSRSRN--TQRRGRSRSARRGRSHSRSPATRGRSRSRT 577

Query: 527  -SEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNA---SPAAREEAT 582
             +     R R  + + + S T  +  +  +  +   +     P R  +   SP  R   +
Sbjct: 578  PARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRS 637

Query: 583  SPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPA----ATQRP 638
               A+    S    P    ++     +R   + R   P  +   S+   PA    +  R 
Sbjct: 638  RSPARRSGRSRSRTPARRGRSRSRTPARRGRS-RSRTPARRSGRSRSRTPARRGRSRSRT 696

Query: 639  PSNGGAKETS-------HASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSG------H 685
            P  G ++  S       H+  PQ     G  S+  KN    S      N           
Sbjct: 697  PRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSE-RKNKSRTSQRRSRSNSSPEMKKSRIS 755

Query: 686  SAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGE---- 741
            S      +S    +KS  SLR S   S  S  P+  S  P  P     G      +    
Sbjct: 756  SRRSRSLSSPRSKAKSRLSLRRSLSGS--SPCPKQKSQTP--PRRSRSGSSQPKAKSRTP 811

Query: 742  -RKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELAS 800
             R+ R+   P   Q+        P R+   S+  H  +     GT  P    S T+  A+
Sbjct: 812  PRRSRSSSSPPPKQK-----SKTPSRQSHSSSSPHPKVKS---GT--PPRQGSITSPQAN 861

Query: 801  RGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSA---HEPG 857
               +     S  E           SS  PE+K    + +          +SS      P 
Sbjct: 862  EQSVTPQRRSCFE-----------SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPS 910

Query: 858  GSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSM 917
             S S +  V   ISP ++      +HS     + +R+    R  P  S+SV     + S 
Sbjct: 911  RSSSPQPKVKAIISPRQR------SHSGSSSPSPSRV--TSRTTPRRSRSVSPCSNVESR 962

Query: 918  ETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSD 977
                 S SG    +   + K +       SG     P +K ++      PG +   S S 
Sbjct: 963  LLPRYSHSGSSSPDT--KVKPETPPRQSHSGSISPYPKVKAQT-----PPGPSLSGSKSP 1015

Query: 978  YGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRS------RGPGGDPH 1031
               + S+ + ++  PG +    G++  +P     F        G+S      R     P 
Sbjct: 1016 CPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPE 1075

Query: 1032 HMNPH------MTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLHY 1085
                H       + S+ + +       SP +E  + +     R      P   L S +  
Sbjct: 1076 VRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPM--LKSGMSP 1133

Query: 1086 KRQMYQQQPEEYKDWSSGS--AQGVIAAAQHR-------QEGPRKSPRQQQ--------- 1127
            ++  +Q     Y    S S   Q  +  A+ +       QE    SP +Q+         
Sbjct: 1134 EQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQ 1193

Query: 1128 --------FLDRVRSPLKNDKDGMMYGPPVGTYHDP---SAQEAGRCLMSSDGLPNKGME 1176
                    F D +R+P + ++ G    P     +     S+Q+     +        G  
Sbjct: 1194 DRPESSLVFKDTLRTPPR-ERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQI 1252

Query: 1177 LKHGSQKLQESCW-------------------DLSRQTSPAKSSGPPGMSSQ---KRYGP 1214
            L H S +L+E                      D S+  +  ++   P M+S      + P
Sbjct: 1253 LSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSP 1312

Query: 1215 PHETDGHGLAEATQSSKPGSVMLRLP-GQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDV 1273
             H+   +          P       P G E ++  +  +       F++ + +   S D+
Sbjct: 1313 EHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETD-PSLDM 1371

Query: 1274 KNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDSRNCPAVTL 1333
            K  ST   G   HSS E +  A    A +S +Q I S P  D+    PS +  +    + 
Sbjct: 1372 KEQSTRSSG---HSSSELSPDAVEK-AGMSSNQSISS-PVLDAVPRTPSRERSS----SA 1422

Query: 1334 TSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEA-GGDTVTLDDILSLKSGP 1392
            +SP     LP    R  +  +      SP +R  + + S  +  G +  + DI      P
Sbjct: 1423 SSPEMKDGLPRTPSRRSRSGS------SPGLRDGSGTPSRHSLSGSSPGMKDI---PRTP 1473

Query: 1393 PEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAE 1452
              G S      + +           SP++ EL+ +   P+     R   +  V  +T A 
Sbjct: 1474 SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRE---RSGSESSVDQKTVAR 1530

Query: 1453 TVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAE 1512
            T    +   G+      +   S Q R +           PDSK      +     +  + 
Sbjct: 1531 TPLGQRSRSGSSQELDVKPSASPQERSESDSS-------PDSKAKTRTPLRQRSRSGSSP 1583

Query: 1513 EKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIP----- 1567
            E ++ +  +SP++      G  P  K K R      +      P P  P P  +P     
Sbjct: 1584 EVDSKS-RLSPRRSR---SGSSPEVKDKPRAAPRA-QSGSDSSPEPKAPAPRALPRRSRS 1638

Query: 1568 -----------EGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVP 1603
                       EGS+  E  P+   + R  R+      + KTK   P
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTP 1685



 Score = 35.8 bits (81), Expect = 0.42
 Identities = 45/196 (22%), Positives = 71/196 (36%), Gaps = 13/196 (6%)

Query: 57   GGRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQ 116
            G +  ++ A A   S    H G       A    +    + P +TG  QP       P +
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLSV--PAPGVPHSDVGEPPASTGAQQPSALAALQPAK 2528

Query: 117  SYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQ 176
                   SS  +   S        +  S  G  S   +  + P  P  A  +  + +   
Sbjct: 2529 ERRSSSSSSSSSSSSSSS--SSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586

Query: 177  QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQ 236
            ++ V++ R       +P P    + +SSSS        S+  SS++              
Sbjct: 2587 KEAVREGRPP-----EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSSS 2637

Query: 237  SSASSSSSSSFPSPQR 252
            SS+SSSSSSS PSP +
Sbjct: 2638 SSSSSSSSSSSPSPAK 2653



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 66/331 (19%), Positives = 121/331 (36%), Gaps = 50/331 (15%)

Query: 449  TDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKR---PSSSKKADSCTNSEGSS 505
            T P   S S ++++ A  P++      S +L P  +   R   PS+      C  ++ + 
Sbjct: 2409 TPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP 2468

Query: 506  QPEEQLKSPMAESLDGGCSSSSEDQGERVRQLS------GQSTSSDTTYKGGASEK---A 556
                Q  S       G  ++++   G+    LS        S   +     GA +    A
Sbjct: 2469 VAGSQSLS------SGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALA 2522

Query: 557  GSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGR 616
               PA+  ++     ++S ++   ++S  +     SS G+   + +   + V  E    R
Sbjct: 2523 ALQPAKERRSS----SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578

Query: 617  VEKPGGQDKGS------QEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGD 670
            V  P    K +       E  PA  +R  S+  +  +S +S           S  + +  
Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSS----SSSSSSSSSSSSSSS 2634

Query: 671  NNSNHNGEGNGQSGHSAAGPGFTSRTEP------------SKSP----GSLRYSYKDSFG 714
            ++S+ +   +  S  S A PG  +  +P            S+SP     SLR S   S+ 
Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694

Query: 715  SAVPRNVSGFPQYPTGQEKGDFTGHGERKGR 745
                R  S  PQ     ++   +  G R+G+
Sbjct: 2695 PVERRRPS--PQPSPRDQQSSSSERGSRRGQ 2723



 Score = 32.0 bits (71), Expect = 6.1
 Identities = 50/223 (22%), Positives = 70/223 (31%), Gaps = 29/223 (13%)

Query: 1101 SSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEA 1160
            SS S+     ++    EG     + +  L RV SP    K+ +  G P      P    A
Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP------PEPTPA 2601

Query: 1161 GRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPHETDG 1220
             R   SS    +        S     S    S  +S + SS     SS     P      
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSS----SSSSSSSSSSSSSSSSSSSSPSP------ 2651

Query: 1221 HGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVKNSSTED 1280
                     +KPG   L  P     S + P    RR RS   PI S R S+ +  S  E 
Sbjct: 2652 ---------AKPGPQALPKPA----SPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVER 2698

Query: 1281 KGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSP 1323
            +      S      + +        +     P     ++ PSP
Sbjct: 2699 RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 102/357 (28%), Positives = 130/357 (36%), Gaps = 57/357 (15%)

Query: 104 PQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSG--LGGVSHYQQDYTG--- 158
           PQPPQ  PSGP  + G PQ      Q GS    G F  Q  G     +S + Q   G   
Sbjct: 167 PQPPQPAPSGP-PAQGHPQHM---QQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQ 222

Query: 159 --PFSPGSAQYQQQASSQQQQQQVQQLRQQLYQ-SHQPLPQATGQPASSSSHL--QPMQR 213
             PF   S         QQ       LR  + Q  H P     G+  + S      P Q+
Sbjct: 223 GNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVAHSPRFSPNPPQQ 282

Query: 214 PSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSY-NVNAGSQY 272
            +  P                 Q+   SS S + PSP   + SGQ     Y N+N G   
Sbjct: 283 GAVRP-----------------QTLNFSSRSQTVPSP-TINNSGQYSRYPYSNLNQGLV- 323

Query: 273 EGHNVGSNAQAYGTQSNYSYQPQSMKNFEQA-KIPQGTQQGQQQQQPQQQQHPSQHVMQY 331
             +N G N Q  G  +N +   QS+  +  A   P  + QG   QQP    HPS  + Q 
Sbjct: 324 --NNTGMN-QNLGLTNN-TPMNQSVPRYPNAVGFPSNSGQGLMHQQP---IHPSGSLNQ- 375

Query: 332 TNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPS---- 387
            N  T  P Q Q G Y  P  P  SPM+   N  P   P P       P  +  P     
Sbjct: 376 MNTQTMHPSQPQ-GTYASP--PPMSPMKAMSN--PAGTPPPQV----RPGSAGIPMEVGS 426

Query: 388 -PLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGV 443
            P M   +      G++ +G RN   + M Q  P   M  +P       +  G  GV
Sbjct: 427 YPNMPHPQPSHQPPGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGV 483



 Score = 35.0 bits (79), Expect = 0.72
 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 14/105 (13%)

Query: 1492 PDSKNVP--PVGILAPEANPKAEEKENDTVTISPKQE----GFPPKGYFPSGKKK---GR 1542
            P  K  P  P    AP+   + +EK+  T T  PK         P     + KKK   G+
Sbjct: 659  PKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGK 718

Query: 1543 PIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERR 1587
              GS N    +  PP PPP+  + P     G  K +  RQ + +R
Sbjct: 719  TEGSENSDLDKTPPPSPPPEEDEDP-----GVQKRRSSRQVKRKR 758



 Score = 32.3 bits (72), Expect = 4.7
 Identities = 39/174 (22%), Positives = 69/174 (39%), Gaps = 44/174 (25%)

Query: 1510 KAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEG 1569
            K ++K+N+ +      +GF  K  FP G         V+ Q              ++   
Sbjct: 597  KKKKKKNNHIVAEDPSKGFG-KDDFPGG---------VDNQ--------------ELNRN 632

Query: 1570 SADGEPKPKKQRQRRERRKPGAQPRKRKTKQ--------AVPIVEPQEPEIKLKYATQPL 1621
            S DG  + KK+++R + +K   +P++ K K+          P + P+EP+ K      P 
Sbjct: 633  SLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKI-PKEPKEKKAKTATPK 691

Query: 1622 DKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPS 1675
             K+  K+ +  P        E  A+   +N  + E ++           TPPPS
Sbjct: 692  PKSSKKSSNKKP------DSEASALKKKVNKGKTEGSE-----NSDLDKTPPPS 734


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
            sapiens]
          Length = 699

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 102/465 (21%), Positives = 156/465 (33%), Gaps = 85/465 (18%)

Query: 1400 VQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKE 1459
            ++ A + +RK +    +   A ++         S EE         K    A+ V     
Sbjct: 58   LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGL--- 114

Query: 1460 PPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTV 1519
            PPG   +  S+   S +   D           P  K V P    A     KA+  ++D+ 
Sbjct: 115  PPGKAAAKASESSSSEESSDDDDEEDQKKQ--PVQKGVKPQAKAAKAPPKKAKSSDSDSD 172

Query: 1520 TISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEG---SADGEPK 1576
            + S   E  PPK   P        I  V  + + + PP P    P+I  G   S+     
Sbjct: 173  SSS---EDEPPKNQKPK-------ITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSS 222

Query: 1577 PKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQPLDKTDAKNKSFYPYIH 1636
                    E  K  A P+K   K+ V    P      +K AT P  K+ +   S      
Sbjct: 223  SSSSSDDSEEEKAAATPKKTVPKKQVVAKAP------VKAATTPTRKSSSSEDSS----- 271

Query: 1637 VVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESKAL-----PASSFMLQG 1691
                          + EEEEQ K ++ + G  S  PPPS+   K       P  +   Q 
Sbjct: 272  --------------SDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQ 317

Query: 1692 PVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK----RATEMQS 1747
            PV  ESS                 +  D        D ++   K PP K    +AT    
Sbjct: 318  PV--ESS----------------EDSSD------ESDSSSEEEKKPPTKAVVSKATTKPP 353

Query: 1748 KVKVRHKSASNGSKTDTEEEEE--------QQQQQKEQRSLAAHPRFK-RRHRSEDCGGG 1798
              K   +S+S+ S +D+ E++E         +    +       P  K      +  GGG
Sbjct: 354  PAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG 413

Query: 1799 PRSLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIP 1843
             + L+R      +  E SS +     K    T  +   +  L +P
Sbjct: 414  QKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLP 458



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 103/535 (19%), Positives = 190/535 (35%), Gaps = 54/535 (10%)

Query: 1156 SAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPP 1215
            SA+   R L ++  +  K  +    S     S  +   Q  PAK +  P     KR G P
Sbjct: 60   SAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPA----KRVGLP 115

Query: 1216 HETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVKN 1275
                G   A+A++SS   S        E+   + P+    + ++  +  P K+      +
Sbjct: 116  ---PGKAAAKASESSS--SEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSD 170

Query: 1276 SSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTS 1335
            S +  +     + K             +  +  ++ PK  + K   S  S +  + +  S
Sbjct: 171  SDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDS 230

Query: 1336 PAKTKILPPRKG---RGLKLEAIVQKITSPNIRRSASSNSAEAGGDTVTLDDILSLKSGP 1392
              +     P+K    + +  +A V+  T+P  + S+S +S+    +    +    +K+ P
Sbjct: 231  EEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEE----EQKKPMKNKP 286

Query: 1393 PEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRS---SEEWRGSVDDKVKTET 1449
                SV    A   K+     S    P  + +  ++P+  S   S+E   S +++ K  T
Sbjct: 287  GPYSSVPPPSAPPPKK-----SLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPT 341

Query: 1450 HAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPL-IFPDSKNVPPVGILAPEAN 1508
             A    A  +PP A  +  S    S+    +     + P     +S N P V   +P   
Sbjct: 342  KAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVK 401

Query: 1509 PKAEEKE----NDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPP 1564
            P A  K+       +           +    S ++K + + +  K K   +     P   
Sbjct: 402  PAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAK- 460

Query: 1565 QIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQPLDKT 1624
            Q P+GS D            E  K      K+K ++      P +P      A+    K 
Sbjct: 461  QAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKP------ASAKKGKA 514

Query: 1625 DAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTES 1679
            ++ N S                 +  ++ EEE+ KL +G+   R   P  + T +
Sbjct: 515  ESSNSS-----------------SSDDSSEEEEEKL-KGKGSPRPQAPKANGTSA 551



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 70/344 (20%), Positives = 123/344 (35%), Gaps = 28/344 (8%)

Query: 475 LSDALTPQKKTSKRPSSSKKAD---SCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQG 531
           L  A  P++K       +KKA    S ++SE SS+ EE+++ P A+             G
Sbjct: 58  LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG 117

Query: 532 ERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPL 591
           +   + S +S+SS+ +      E     P Q  +   P+  A+ A  ++A S  + D   
Sbjct: 118 KAAAKAS-ESSSSEESSDDDDEEDQKKQPVQ--KGVKPQAKAAKAPPKKAKSSDS-DSDS 173

Query: 592 SSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQ----DKGSQEDDPAATQRPPSNGGAKET 647
           SS+  P  N+K     V+ +A T    KP         G      +++    S+  ++E 
Sbjct: 174 SSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEE 233

Query: 648 SHASLPQ----------PEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTE 697
             A+ P+            P     +   K+  +  + + E   Q       PG  S   
Sbjct: 234 KAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVP 293

Query: 698 PSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVL 757
           P  +P       K S G+  P+      Q     E  D +   +     EK P     V 
Sbjct: 294 PPSAPPP-----KKSLGTQPPKKAVEKQQPVESSE--DSSDESDSSSEEEKKPPTKAVVS 346

Query: 758 QGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASR 801
           +     P  + +  +      + S E    P+     T   +++
Sbjct: 347 KATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNK 390



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 50/236 (21%), Positives = 89/236 (37%), Gaps = 24/236 (10%)

Query: 481 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540
           P+K   K+       DS   S+ SS  EE+ K P    +    +++     ++  + S  
Sbjct: 309 PKKAVEKQQPVESSEDSSDESDSSS--EEEKKPPTKAVVSK--ATTKPPPAKKAAESSSD 364

Query: 541 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600
           S+ SD++    A  K   +  + + N+P     SPA +  A    A   P+   G  K  
Sbjct: 365 SSDSDSSEDDEAPSKPAGT-TKNSSNKPAVTTKSPAVKPAA----APKQPVG--GGQK-- 415

Query: 601 EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660
                 +++R+A +   E+     +  +     AT +P +   A      SLP  + P G
Sbjct: 416 ------LLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAA----LSLPAKQAPQG 465

Query: 661 GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSA 716
                + +  ++S    E   +S              PSK P S +    +S  S+
Sbjct: 466 SRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSK-PASAKKGKAESSNSS 520



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 41/221 (18%), Positives = 75/221 (33%), Gaps = 13/221 (5%)

Query: 481 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKS----PMAESLDGGCSSSSEDQ-----G 531
           P KK ++  S S  +DS  + E  S+P    K+    P   +       ++  +     G
Sbjct: 354 PAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG 413

Query: 532 ERVRQLSGQSTSSDTTYKGGASEKA----GSSPAQGAQNEPPRLNASPAAREEATSPGAK 587
           +++      S+SS+        EK      ++  +        L A  A +    S    
Sbjct: 414 QKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDS 473

Query: 588 DMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKET 647
           D   S +   K ++  V     + A      KP    KG  E   +++    S    ++ 
Sbjct: 474 DSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL 533

Query: 648 SHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAA 688
                P+P+ P   G+      +  +  N E   +    AA
Sbjct: 534 KGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAA 574



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 71/331 (21%), Positives = 115/331 (34%), Gaps = 38/331 (11%)

Query: 1263 PIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPK-RDSSKDLP 1321
            P+ S   S D  +SS+E++ +    +K    KA         + +  S     DSS+D  
Sbjct: 318  PVESSEDSSDESDSSSEEEKK--PPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDE 375

Query: 1322 SP--------DSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSA 1373
            +P        +S N PAVT  SPA      P++  G   + + +K  S +    +SS+  
Sbjct: 376  APSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEE 435

Query: 1374 EAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRS 1433
            E    T  +      K+      S+  + A    R     SD  S   +E    K   + 
Sbjct: 436  E---KTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKK 492

Query: 1434 SEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPD 1493
              +    V         A       E   + +S  S +    + +  GS    AP     
Sbjct: 493  KPQ---KVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGT 549

Query: 1494 SKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQ 1553
            S      G  A  +  + EEK+   V +S                      GS+ K+K+ 
Sbjct: 550  SALTAQNGKAAKNSEEEEEEKKKAAVVVSKS--------------------GSLKKRKQN 589

Query: 1554 Q-QPPPPPPQPPQIPEGSADGEPKPKKQRQR 1583
            +       PQ  +I   + +  PK KK  +R
Sbjct: 590  EAAKEAETPQAKKIKLQTPNTFPKRKKGEKR 620


>gi|93141033 PAX interacting protein 1 [Homo sapiens]
          Length = 1069

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 64/237 (27%), Positives = 89/237 (37%), Gaps = 39/237 (16%)

Query: 149 VSHYQQDYTGP---------FSPGSAQYQQQASSQQQQ----------QQVQQLRQQLYQ 189
           V+H QQ +T            +P +   QQQ  +QQQQ          QQ+ QL+QQ  Q
Sbjct: 374 VNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQ 433

Query: 190 --SHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSF 247
             S QP PQ    P S     Q  Q+    P   +  QL+  Q   H             
Sbjct: 434 QISQQPYPQQPPHPFSQ----QQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489

Query: 248 PSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQ 307
           P  Q+ +   Q +          Q + H +     A   Q +   Q Q  +  +Q ++  
Sbjct: 490 PFQQQHALQQQFH----------QLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQL-- 537

Query: 308 GTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNF 364
             +  QQQQQ Q Q   + H+ Q + A        Q  Q  Q + P  SP Q HQ F
Sbjct: 538 -QRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQ-HQLF 592



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 64/215 (29%), Positives = 81/215 (37%), Gaps = 40/215 (18%)

Query: 166 QYQQQASSQQQQ--------QQVQQLRQQLYQ--SHQPLPQATGQPASSSSHLQPMQRPS 215
           Q QQQA  QQQQ        QQ+ QL+QQ  Q  S QP PQ    P S     Q  Q+  
Sbjct: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQ----QQQQQQQ 457

Query: 216 TLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGH 275
             P   +  QL+  Q   H               PQ+  +  Q        +A  Q    
Sbjct: 458 AHPHQFSQQQLQFPQQQLH--------------PPQQLHRPQQQLQPFQQQHALQQ---- 499

Query: 276 NVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAA 335
                 Q +  Q +   Q Q  +  +Q  + Q  QQ QQQ Q QQ Q   Q   Q    +
Sbjct: 500 ------QFHQLQQHQLQQQQLAQLQQQHSLLQ--QQQQQQIQQQQLQRMHQQQQQQQMQS 551

Query: 336 TKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNP 370
              P  SQ  Q  Q +VP + P Q  Q   P  +P
Sbjct: 552 QTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSP 586



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 54/202 (26%), Positives = 74/202 (36%), Gaps = 26/202 (12%)

Query: 138 QFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQA 197
           Q Q Q         Y Q    PFS    Q QQ    Q  QQQ+Q  +QQL+      PQ 
Sbjct: 426 QLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHP-----PQQ 480

Query: 198 TGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSG 257
             +P      LQP Q+   L      +QL+  Q  Q   +      S      Q+  Q  
Sbjct: 481 LHRP---QQQLQPFQQQHALQQQF--HQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQ 535

Query: 258 QSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQ 317
           Q            Q +   + S    + +Q++ + Q Q          PQ   Q QQQQQ
Sbjct: 536 QLQ------RMHQQQQQQQMQSQTAPHLSQTSQALQHQVP--------PQQPPQQQQQQQ 581

Query: 318 PQQQQHPSQHVMQYTNAATKLP 339
           P     P QH +   + A ++P
Sbjct: 582 PPPS--PQQHQLFGHDPAVEIP 601



 Score = 38.9 bits (89), Expect = 0.050
 Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 5/72 (6%)

Query: 287 QSNYSYQPQSMKN---FEQAKIPQGTQQGQQQQQP--QQQQHPSQHVMQYTNAATKLPLQ 341
           Q N+S Q  +  N   F Q K+   T   QQQQQ   QQQQHP  H+        +   Q
Sbjct: 373 QVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQ 432

Query: 342 SQVGQYNQPEVP 353
            Q+ Q   P+ P
Sbjct: 433 QQISQQPYPQQP 444



 Score = 35.4 bits (80), Expect = 0.55
 Identities = 35/116 (30%), Positives = 46/116 (39%), Gaps = 16/116 (13%)

Query: 108 QRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQY 167
           Q++   P Q   PPQ       +  +  +  FQ QH+        QQ          AQ 
Sbjct: 465 QQQLQFPQQQLHPPQ-----QLHRPQQQLQPFQQQHALQQQFHQLQQHQLQ--QQQLAQL 517

Query: 168 QQQASSQQQQQQVQQLRQQLYQSHQPLPQA---------TGQPASSSSHLQPMQRP 214
           QQQ S  QQQQQ Q  +QQL + HQ   Q            Q + +  H  P Q+P
Sbjct: 518 QQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQP 573


>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
          Length = 1083

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 74/297 (24%), Positives = 103/297 (34%), Gaps = 39/297 (13%)

Query: 31  SPR-QAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASET-----SGHQGYQGFRK 84
           SPR  + M  + GG  G  GS G GSGG  RG       +  +T       ++GY G  K
Sbjct: 662 SPRISSPMHPSAGGQRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVK 721

Query: 85  EAGD----------FYYMAGNKDPVTTGTPQPPQRRPSGPVQSYG-PPQGSSFGNQYGSE 133
           +A +             ++ ++  +TT       RRP G   +YG  P   S    YGS 
Sbjct: 722 DATESTARVELHSTCQTISVDRQRLTT----VGSRRPGGMTSTYGRTPMYGSQTPMYGSG 777

Query: 134 GHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQ---- 189
                + +Q     G          P   GS    Q  +            ++ Y+    
Sbjct: 778 SRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFD 837

Query: 190 ----------SHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSA 239
                        P PQ  G P  SS  + P   P T P + A Y     QF  +   S 
Sbjct: 838 DEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQT-PGTPAMY--NTDQFSPYAAPSP 894

Query: 240 SSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS 296
             S   S PSPQ + Q   S  G  N ++ + Y         QA  + S   Y P +
Sbjct: 895 QGSYQPS-PSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMT 950



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 49/209 (23%), Positives = 67/209 (32%), Gaps = 43/209 (20%)

Query: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQ--QPQQQQHPSQ 326
           GSQ   +  GS    YG+Q+      ++     Q  +  G++   Q     P     PS+
Sbjct: 768 GSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSR 827

Query: 327 HVMQYTNAATKLPLQS---------------------QVGQYNQPEVPVRSPMQFHQNFS 365
              +Y  A    P  S                     QV     P+ P    M     FS
Sbjct: 828 AEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFS 887

Query: 366 PISNPSPAASVVQSPSCSS----TPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPT 421
           P + PSP  S   SPS  S     PSP      +        P         +  Q SP+
Sbjct: 888 PYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPS-------PMAYQASPS 940

Query: 422 PSMM---------PSPNSHAAGFKGFGLE 441
           PS +         PSP  +     G G+E
Sbjct: 941 PSPVGYSPMTPGAPSPGGYNPHTPGSGIE 969



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 42/164 (25%), Positives = 50/164 (30%), Gaps = 38/164 (23%)

Query: 1455 TAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLI-----FPDSKNVPPVGILAP---- 1505
            T G   PG MTST  + P      P    G   P+        D    P  G   P    
Sbjct: 748  TVGSRRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDG 807

Query: 1506 -----------EANP----KAEEKE----NDTVTISPKQEGFPPKGYFPSGKKKGRPIGS 1546
                         NP    +AEE+     +D  T SP+  G  P    P       P   
Sbjct: 808  SRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSP--Q 865

Query: 1547 VNKQKKQQQPPPP--------PPQPPQIPEGSADGEPKPKKQRQ 1582
            VN Q   Q P  P         P     P+GS    P P+   Q
Sbjct: 866  VNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQ 909


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 74/297 (24%), Positives = 103/297 (34%), Gaps = 39/297 (13%)

Query: 31  SPR-QAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASET-----SGHQGYQGFRK 84
           SPR  + M  + GG  G  GS G GSGG  RG       +  +T       ++GY G  K
Sbjct: 666 SPRISSPMHPSAGGQRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVK 725

Query: 85  EAGD----------FYYMAGNKDPVTTGTPQPPQRRPSGPVQSYG-PPQGSSFGNQYGSE 133
           +A +             ++ ++  +TT       RRP G   +YG  P   S    YGS 
Sbjct: 726 DATESTARVELHSTCQTISVDRQRLTT----VGSRRPGGMTSTYGRTPMYGSQTPMYGSG 781

Query: 134 GHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQ---- 189
                + +Q     G          P   GS    Q  +            ++ Y+    
Sbjct: 782 SRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFD 841

Query: 190 ----------SHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSA 239
                        P PQ  G P  SS  + P   P T P + A Y     QF  +   S 
Sbjct: 842 DEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQT-PGTPAMY--NTDQFSPYAAPSP 898

Query: 240 SSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS 296
             S   S PSPQ + Q   S  G  N ++ + Y         QA  + S   Y P +
Sbjct: 899 QGSYQPS-PSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMT 954



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 49/209 (23%), Positives = 67/209 (32%), Gaps = 43/209 (20%)

Query: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQ--QPQQQQHPSQ 326
           GSQ   +  GS    YG+Q+      ++     Q  +  G++   Q     P     PS+
Sbjct: 772 GSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSR 831

Query: 327 HVMQYTNAATKLPLQS---------------------QVGQYNQPEVPVRSPMQFHQNFS 365
              +Y  A    P  S                     QV     P+ P    M     FS
Sbjct: 832 AEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFS 891

Query: 366 PISNPSPAASVVQSPSCSS----TPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPT 421
           P + PSP  S   SPS  S     PSP      +        P         +  Q SP+
Sbjct: 892 PYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPS-------PMAYQASPS 944

Query: 422 PSMM---------PSPNSHAAGFKGFGLE 441
           PS +         PSP  +     G G+E
Sbjct: 945 PSPVGYSPMTPGAPSPGGYNPHTPGSGIE 973



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 42/164 (25%), Positives = 50/164 (30%), Gaps = 38/164 (23%)

Query: 1455 TAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLI-----FPDSKNVPPVGILAP---- 1505
            T G   PG MTST  + P      P    G   P+        D    P  G   P    
Sbjct: 752  TVGSRRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDG 811

Query: 1506 -----------EANP----KAEEKE----NDTVTISPKQEGFPPKGYFPSGKKKGRPIGS 1546
                         NP    +AEE+     +D  T SP+  G  P    P       P   
Sbjct: 812  SRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSP--Q 869

Query: 1547 VNKQKKQQQPPPP--------PPQPPQIPEGSADGEPKPKKQRQ 1582
            VN Q   Q P  P         P     P+GS    P P+   Q
Sbjct: 870  VNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQ 913


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 74/297 (24%), Positives = 103/297 (34%), Gaps = 39/297 (13%)

Query: 31  SPR-QAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASET-----SGHQGYQGFRK 84
           SPR  + M  + GG  G  GS G GSGG  RG       +  +T       ++GY G  K
Sbjct: 666 SPRISSPMHPSAGGQRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVK 725

Query: 85  EAGD----------FYYMAGNKDPVTTGTPQPPQRRPSGPVQSYG-PPQGSSFGNQYGSE 133
           +A +             ++ ++  +TT       RRP G   +YG  P   S    YGS 
Sbjct: 726 DATESTARVELHSTCQTISVDRQRLTT----VGSRRPGGMTSTYGRTPMYGSQTPMYGSG 781

Query: 134 GHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQ---- 189
                + +Q     G          P   GS    Q  +            ++ Y+    
Sbjct: 782 SRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFD 841

Query: 190 ----------SHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSA 239
                        P PQ  G P  SS  + P   P T P + A Y     QF  +   S 
Sbjct: 842 DEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQT-PGTPAMY--NTDQFSPYAAPSP 898

Query: 240 SSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS 296
             S   S PSPQ + Q   S  G  N ++ + Y         QA  + S   Y P +
Sbjct: 899 QGSYQPS-PSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMT 954



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 49/209 (23%), Positives = 67/209 (32%), Gaps = 43/209 (20%)

Query: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQ--QPQQQQHPSQ 326
           GSQ   +  GS    YG+Q+      ++     Q  +  G++   Q     P     PS+
Sbjct: 772 GSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSR 831

Query: 327 HVMQYTNAATKLPLQS---------------------QVGQYNQPEVPVRSPMQFHQNFS 365
              +Y  A    P  S                     QV     P+ P    M     FS
Sbjct: 832 AEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFS 891

Query: 366 PISNPSPAASVVQSPSCSS----TPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPT 421
           P + PSP  S   SPS  S     PSP      +        P         +  Q SP+
Sbjct: 892 PYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPS-------PMAYQASPS 944

Query: 422 PSMM---------PSPNSHAAGFKGFGLE 441
           PS +         PSP  +     G G+E
Sbjct: 945 PSPVGYSPMTPGAPSPGGYNPHTPGSGIE 973



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 42/164 (25%), Positives = 50/164 (30%), Gaps = 38/164 (23%)

Query: 1455 TAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLI-----FPDSKNVPPVGILAP---- 1505
            T G   PG MTST  + P      P    G   P+        D    P  G   P    
Sbjct: 752  TVGSRRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDG 811

Query: 1506 -----------EANP----KAEEKE----NDTVTISPKQEGFPPKGYFPSGKKKGRPIGS 1546
                         NP    +AEE+     +D  T SP+  G  P    P       P   
Sbjct: 812  SRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSP--Q 869

Query: 1547 VNKQKKQQQPPPP--------PPQPPQIPEGSADGEPKPKKQRQ 1582
            VN Q   Q P  P         P     P+GS    P P+   Q
Sbjct: 870  VNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQ 913


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 74/297 (24%), Positives = 103/297 (34%), Gaps = 39/297 (13%)

Query: 31  SPR-QAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASET-----SGHQGYQGFRK 84
           SPR  + M  + GG  G  GS G GSGG  RG       +  +T       ++GY G  K
Sbjct: 666 SPRISSPMHPSAGGQRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVK 725

Query: 85  EAGD----------FYYMAGNKDPVTTGTPQPPQRRPSGPVQSYG-PPQGSSFGNQYGSE 133
           +A +             ++ ++  +TT       RRP G   +YG  P   S    YGS 
Sbjct: 726 DATESTARVELHSTCQTISVDRQRLTT----VGSRRPGGMTSTYGRTPMYGSQTPMYGSG 781

Query: 134 GHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQ---- 189
                + +Q     G          P   GS    Q  +            ++ Y+    
Sbjct: 782 SRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFD 841

Query: 190 ----------SHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSA 239
                        P PQ  G P  SS  + P   P T P + A Y     QF  +   S 
Sbjct: 842 DEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQT-PGTPAMY--NTDQFSPYAAPSP 898

Query: 240 SSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS 296
             S   S PSPQ + Q   S  G  N ++ + Y         QA  + S   Y P +
Sbjct: 899 QGSYQPS-PSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMT 954



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 49/209 (23%), Positives = 67/209 (32%), Gaps = 43/209 (20%)

Query: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQ--QPQQQQHPSQ 326
           GSQ   +  GS    YG+Q+      ++     Q  +  G++   Q     P     PS+
Sbjct: 772 GSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSR 831

Query: 327 HVMQYTNAATKLPLQS---------------------QVGQYNQPEVPVRSPMQFHQNFS 365
              +Y  A    P  S                     QV     P+ P    M     FS
Sbjct: 832 AEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFS 891

Query: 366 PISNPSPAASVVQSPSCSS----TPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPT 421
           P + PSP  S   SPS  S     PSP      +        P         +  Q SP+
Sbjct: 892 PYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPS-------PMAYQASPS 944

Query: 422 PSMM---------PSPNSHAAGFKGFGLE 441
           PS +         PSP  +     G G+E
Sbjct: 945 PSPVGYSPMTPGAPSPGGYNPHTPGSGIE 973



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 42/164 (25%), Positives = 50/164 (30%), Gaps = 38/164 (23%)

Query: 1455 TAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLI-----FPDSKNVPPVGILAP---- 1505
            T G   PG MTST  + P      P    G   P+        D    P  G   P    
Sbjct: 752  TVGSRRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDG 811

Query: 1506 -----------EANP----KAEEKE----NDTVTISPKQEGFPPKGYFPSGKKKGRPIGS 1546
                         NP    +AEE+     +D  T SP+  G  P    P       P   
Sbjct: 812  SRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSP--Q 869

Query: 1547 VNKQKKQQQPPPP--------PPQPPQIPEGSADGEPKPKKQRQ 1582
            VN Q   Q P  P         P     P+GS    P P+   Q
Sbjct: 870  VNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQ 913


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 122/525 (23%), Positives = 188/525 (35%), Gaps = 79/525 (15%)

Query: 199 GQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQ---RFSQ 255
           G P +S   +  M  P+T+     G              + SSS  +  P+P+   R  +
Sbjct: 164 GFPMASGPGIIRMNNPATVMIPPGG--------------NVSSSMMAPGPNPELQPRTPR 209

Query: 256 SGQSYDGSYNVNAGS--QYEGHNVGSNAQAYGTQSNYSYQPQSM-KNFEQAKIPQGTQQG 312
                D    + +G   Q + H  GS A  +     +  QP S+ +    A  PQ  QQ 
Sbjct: 210 PASQSDAMDPLLSGLHIQQQSHPSGSLAPPH-----HPMQPVSVNRQMNPANFPQLQQQQ 264

Query: 313 QQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSP 372
           QQQQQ QQQQ   Q   Q      +  LQ++  Q +Q + P     QF    +P   P P
Sbjct: 265 QQQQQQQQQQQQQQQQQQ------QQQLQARPPQQHQQQQPQGIRPQF---TAPTQVPVP 315

Query: 373 AASVVQSPSCSSTPSPLMQTGENLQCGQG--SVPM-GSRNRILQLMPQLS--PTPSMMPS 427
                Q PS +  P P   +   +   QG    P+ G   + LQ  P L+   TPS  P 
Sbjct: 316 -PGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPP 374

Query: 428 PNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALST-QVANL---PNTVQHMLLSDALTPQK 483
           P         FG +   +     P +S+    +  Q+ +L   P+ V   L    LT  K
Sbjct: 375 PYP-------FGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLT-NK 426

Query: 484 KTSKRPSSSKKADSCTNSEGSSQPEEQL--KSPMAESLDGGCSSSSEDQGERVRQLSGQS 541
             +  PSS ++  S  +S   +Q ++Q+  + P    L  G        G       G  
Sbjct: 427 SPASSPSSFQQG-SPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNV 485

Query: 542 TSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNE 601
             +    +          P QG Q+  P L   P       S G  +        P    
Sbjct: 486 PPNFMVMQ-------QQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTA 538

Query: 602 KTVGVIVSREAMTGR-VEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660
            T G   + +    + V+  GGQ  G  ++    +  PP           ++ QP   G 
Sbjct: 539 TTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPP-----------NMMQPSLMGI 587

Query: 661 GGSKGNKNGDNN-----SNHNGEGNGQSGHSAAGPGFTSRTEPSK 700
            G+  N+    +     +  N +G  Q G  +   G   +  PS+
Sbjct: 588 HGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQ 632



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 111/464 (23%), Positives = 152/464 (32%), Gaps = 86/464 (18%)

Query: 83  RKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQ 142
           R EAG  + MA     +    P      P G V S     G +   Q  +     Q  A 
Sbjct: 160 RMEAG--FPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAM 217

Query: 143 HSGLGGVSHYQQDYTG--------PFSPGSA------------QYQQQASSQQQQQQVQQ 182
              L G+   QQ +          P  P S             Q QQQ   QQQQQQ QQ
Sbjct: 218 DPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQ 277

Query: 183 LRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQF-GQHYQSSASS 241
            +QQ  Q  Q  P    Q             P+ +P      QL  G       Q S  +
Sbjct: 278 QQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGT 337

Query: 242 SSSS----SFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSM 297
            +++      P P    Q  Q+      V   S         + QA    +N+   PQ M
Sbjct: 338 MTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNF---PQ-M 393

Query: 298 KNFEQAKIPQ-GTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRS 356
            N  Q   PQ  + QG   + P   Q P       TN +                 P  S
Sbjct: 394 SNPGQFTAPQMKSLQGGPSRVPTPLQQP-----HLTNKS-----------------PASS 431

Query: 357 PMQFHQNFSPISNPSPAASVVQ--------SPSCSSTPSPLMQTGENLQCGQGSVPMGSR 408
           P  F Q  SP S+P+   +  Q        +P       P+   G N    QG+VP    
Sbjct: 432 PSSFQQG-SPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVP--PN 488

Query: 409 NRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPN 468
             ++Q  P      S+ P            GL G+P KRL  PG S+  A        PN
Sbjct: 489 FMVMQQQPPNQGPQSLHP------------GLGGMP-KRL-PPGFSAGQA-------NPN 527

Query: 469 TVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLK 512
            +Q  + S   T    +      + +       +G+  P+ Q++
Sbjct: 528 FMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQ 571



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 69/253 (27%), Positives = 97/253 (38%), Gaps = 46/253 (18%)

Query: 293  QPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEV 352
            QPQ     +Q   P    Q QQQQQ QQQQ     +MQ    + +LP+   V     P  
Sbjct: 1004 QPQPQLPQQQQPPPPSQPQSQQQQQ-QQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLN 1062

Query: 353  P--VRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNR 410
            P   R PMQ   +   + +    ASV  SP     P P+            + P+GS +R
Sbjct: 1063 PDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPV------------NTPLGSNSR 1110

Query: 411  --ILQLMPQ---LSPTPSMMPSPNSHAAGFKGFGLEG----------VPEKRL----TDP 451
              + Q  PQ    SP   M   P   A+G +   + G          +P+ +L      P
Sbjct: 1111 KMVYQESPQNPSSSPLAEMASLP--EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKP 1168

Query: 452  GLSSLSAL------STQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKK----ADSCTNS 501
            G S LSA          V +LP++  H   + A   Q    K P+ +        +  N 
Sbjct: 1169 GPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNR 1228

Query: 502  EGSSQPEEQLKSP 514
              S++P E   SP
Sbjct: 1229 PPSTEPSEISLSP 1241



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 86/361 (23%), Positives = 120/361 (33%), Gaps = 52/361 (14%)

Query: 81  GFRKEAGDFYYMAGNKDPVTTGTPQ---PPQRRPSGPVQ-----SYGPPQGSSFGNQYGS 132
           GF     +  +M G     T  TP     PQ + +  VQ       GPPQ         S
Sbjct: 518 GFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQ----MQVS 573

Query: 133 EGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQ 192
            G     Q    G+ G  + QQ        G++   Q   S  Q Q  Q    QL   HQ
Sbjct: 574 HGPPNMMQPSLMGIHGNMNNQQ-------AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQ 626

Query: 193 PLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQR 252
            +  + GQ       L P Q P  L  +         Q     Q   +  S +  PSPQR
Sbjct: 627 QIVPSQGQMVQQQGTLNP-QNPMILSRA---------QLMPQGQMMVNPPSQNLGPSPQR 676

Query: 253 FSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGT-QQ 311
            +   Q           SQ     +  + Q  G Q     Q   M         QG  QQ
Sbjct: 677 MTPPKQML---------SQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQ 727

Query: 312 GQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPS 371
              Q Q      P+Q +M+      +  +    GQ +   +P + P+    N SP     
Sbjct: 728 FNTQNQSNVMPGPAQ-IMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV----NNSPSQVMG 782

Query: 372 PAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSH 431
               V++ P     PSP M      Q G  +    +   + Q+MP +S   + M  P+  
Sbjct: 783 IQGQVLRPPG----PSPHMAQ----QHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQ 834

Query: 432 A 432
           A
Sbjct: 835 A 835



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 85/377 (22%), Positives = 134/377 (35%), Gaps = 61/377 (16%)

Query: 153  QQDYTGPFSPGSAQYQQQASSQQQQQQVQQ--------LRQQLYQSHQPL-PQATGQPAS 203
            QQ    P  P S Q QQQ         +QQ        + Q ++    PL P +   P  
Sbjct: 1012 QQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQ 1071

Query: 204  SSSHLQPM---QRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSY 260
             S  +  M   Q P+++P S    ++       +    ++S       SPQ  S S  + 
Sbjct: 1072 QSGSVPVMVSLQGPASVPPSPDKQRM---PMPVNTPLGSNSRKMVYQESPQNPSSSPLAE 1128

Query: 261  DGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS---MKNFEQAKIPQGTQQGQQQQQ 317
              S    +GS+      G N        ++   PQ+   M   +    P    QG   QQ
Sbjct: 1129 MASLPEASGSEAPSVPGGPN-----NMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQ 1183

Query: 318  PQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVV 377
            P     PS H   + N A          Q ++P+ P R+  + +   +P + P       
Sbjct: 1184 PPVNSLPSSHGHHFPNVAAPT-------QTSRPKTPNRASPRPYYPQTPNNRPP------ 1230

Query: 378  QSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKG 437
                 S+ PS +  + E L              I  L P     P + P PN +    +G
Sbjct: 1231 -----STEPSEISLSPERLNAS-----------IAGLFPPQINIP-LPPRPNLN----RG 1269

Query: 438  FGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADS 497
            F  +G+    L   G  + S L+   +N      H L S  +   K+++   S + K  S
Sbjct: 1270 FDQQGLNPTTLKAIG-QAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSN---SGATKRAS 1325

Query: 498  CTNSEGSSQPEEQLKSP 514
             +NS  SS    +  +P
Sbjct: 1326 PSNSRRSSPGSSRKTTP 1342



 Score = 38.1 bits (87), Expect = 0.085
 Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 12/130 (9%)

Query: 1466 STTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQ 1525
            +T + KP   +  P         L  PD++   P G+   +  P   E+  +     PK 
Sbjct: 908  NTNANKPKKKKP-PRKKKNSQQDLNTPDTR---PAGLEEADQPPLPGEQGINLDNSGPKL 963

Query: 1526 EGFP--PKGYFPSGKKKGRPIGSVNKQKKQQ-QPPPPPPQ---PPQIPEGSADGEP-KPK 1578
              F   P GY PS   + RP+  +  Q  Q   PPP PPQ    PQ+P+      P +P+
Sbjct: 964  PEFSNRPPGY-PSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQ 1022

Query: 1579 KQRQRRERRK 1588
             Q+Q++++++
Sbjct: 1023 SQQQQQQQQQ 1032


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 102/424 (24%), Positives = 154/424 (36%), Gaps = 95/424 (22%)

Query: 162 PGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPS-- 219
           P    Y QQ   QQQQQQ QQ +QQ  Q  Q   Q   Q  SS S  Q  Q+ S++ +  
Sbjct: 581 PSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQ 640

Query: 220 ------SAAGYQLRVGQFGQHYQSSASSSSSSSFP------SPQRFSQ-------SGQSY 260
                      Q +  Q  Q  Q   SS  + S P      SP    Q         Q  
Sbjct: 641 QQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPI 700

Query: 261 DG-SYNVNAGSQYEGHN-VGSN---------AQAYGTQSNYSYQPQSMKNFE-------- 301
            G  Y V+   + + H+ VG N              T S Y    QS+ N +        
Sbjct: 701 AGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTL 760

Query: 302 QAKIPQGTQQGQQQQQ---------PQQQ--QHPSQHVMQYTNAATKLPLQSQVGQYN-- 348
           Q +I +  QQ   QQQ         PQ Q  +H S+    Y +    +       QY+  
Sbjct: 761 QRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGG 820

Query: 349 ------QPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ-- 400
                      + +P+  H   +P S+    +   + PS S+    +   G NL C Q  
Sbjct: 821 SSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYG-NLPCNQPN 879

Query: 401 ------GSVPMGSRNRILQLM-----PQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLT 449
                 G   +  +    QL+     P +   P++ PS N++ A    FG   V   +  
Sbjct: 880 TYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVA---TFGAGSVGNSQQL 936

Query: 450 DPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEE 509
            P L+        +A++P             PQ+ ++   +S+  A +  + EG+S+ +E
Sbjct: 937 RPNLTH------SMASMP-------------PQRTSNVMITSNTTAPNWASQEGTSKQQE 977

Query: 510 QLKS 513
            L S
Sbjct: 978 ALTS 981



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 49/198 (24%), Positives = 70/198 (35%), Gaps = 34/198 (17%)

Query: 977  DYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPH----H 1032
            D G Q  R TP   +P                      K + SPG ++GP G P      
Sbjct: 343  DLGQQSQRSTPRPSLP----------------MEKIVIKSEYSPGLTQGPSGSPQLRPPS 386

Query: 1033 MNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRA--------HAYGDPNAGLNSQLH 1084
              P  + +  A  +S   P  P S+         +RA        HA        N Q H
Sbjct: 387  AGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQH 446

Query: 1085 YKRQMYQQQPEEYKDWSS-GSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGM 1143
             + Q +QQQ  +  +WS+  S+ G       +++ P  S  QQ F  +  SP+     G 
Sbjct: 447  ARMQQHQQQ-HQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQ-SSPMPGVAGGS 504

Query: 1144 MYGPPVGTY---HDPSAQ 1158
                 +  Y     PSAQ
Sbjct: 505  GQSKVMANYMYKAGPSAQ 522



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 36/185 (19%), Positives = 65/185 (35%), Gaps = 7/185 (3%)

Query: 1026 PGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLHY 1085
            P  +P   N    F   +++++   P    S+   S  H   +             Q   
Sbjct: 547  PAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQ 606

Query: 1086 KRQMYQQQPEEYKDWSSGSAQ-------GVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKN 1138
            ++Q  QQQ ++ +  SS SAQ        + A  Q +Q+  ++  +QQQ   + +   + 
Sbjct: 607  QQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQP 666

Query: 1139 DKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPA 1198
                    P       P   +    L      P  GM  +   Q+ Q+    + + T P+
Sbjct: 667  SSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPS 726

Query: 1199 KSSGP 1203
             S  P
Sbjct: 727  PSPNP 731


>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
            sapiens]
          Length = 776

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 95/463 (20%), Positives = 157/463 (33%), Gaps = 55/463 (11%)

Query: 1199 KSSGPPGMSSQKRYGPP-------------HETDGHGLAEATQSSKPGSVMLRLPGQEDH 1245
            +  GPPG+S Q   G P              +  G G  E T+  +    +L+     D 
Sbjct: 138  REPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTG-PEDTEGGRHAPELLKHQLLGDL 196

Query: 1246 SSQNPLIMRRRVRSFISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHS 1305
              + P +     +          + +DV  SS +D      S    A  A +     + +
Sbjct: 197  HQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQD------SPPSKASPAQDGRPPQTAA 250

Query: 1306 QDIKSIPKRDSSKDLPSPD------SRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKI 1359
            ++  SIP   +   +P P       S   PA     P+  +     KG+   LE      
Sbjct: 251  REATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRA----KGQDAPLEFTFHVE 306

Query: 1360 TSPNIRRSASSNSAEAGGDTVTLDDILSLKS-GPPEGGSVAVQDADIEKRKGEVASDLVS 1418
             +PN+++  + +    G            ++ GP  G      D      K   A+    
Sbjct: 307  ITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK 366

Query: 1419 PANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGR 1478
            P ++   ++  +   S++  GS D K KT T +   T    P     S     PGS+   
Sbjct: 367  PVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRP---CLSPKHPTPGSS--- 420

Query: 1479 PDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGK 1538
             D  +  ++P + P+  + P            +  KE        K +   P+G  P G+
Sbjct: 421  -DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQ 479

Query: 1539 KKGRPIGSVNKQKKQQQPPPPPPQPPQI----------PEGSADGEPKPKKQRQRRERRK 1588
            K     G  N  +   + PP P  PP            P G      +P K   R     
Sbjct: 480  K-----GQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSS 534

Query: 1589 PGA--QPRKRKTKQAVPIVEPQEPEIKLKYATQPLDKTDAKNK 1629
            PG+   P  R    ++P    +EP+      T P   + AK++
Sbjct: 535  PGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSR 577



 Score = 32.3 bits (72), Expect = 4.7
 Identities = 58/279 (20%), Positives = 99/279 (35%), Gaps = 38/279 (13%)

Query: 483 KKTSKRPSSSKKADSCTNSEGSSQPEE------------QLKSPMAESLDGGCSSSSEDQ 530
           K +++ P+S     S   ++G   P E            + ++   E L       +  +
Sbjct: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE 333

Query: 531 GERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEP----PRLNASPAAREEATSPGA 586
           G   R   G S   DT  +    E +   PA   + +P    P+L A   ++       +
Sbjct: 334 GPEAR---GPSLGEDTK-EADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSK-------S 382

Query: 587 KDMPLSSDGNPKVNEKTVG-VIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAK 645
           KD   S D   K + ++    + +R  ++ +   PG  D   Q   PA    PPS+   K
Sbjct: 383 KDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSS--PK 440

Query: 646 ETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSL 705
             S  +       G  G+K  K        +G+    +   AA PG   +   ++ P   
Sbjct: 441 HVSSVT----SRTGSSGAKEMK----LKGADGKTKIATPRGAAPPGQKGQANATRIPAKT 492

Query: 706 RYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKG 744
             + K    SA  +     P      E+G+    G+R G
Sbjct: 493 PPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSG 531


>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
            sapiens]
          Length = 758

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 92/451 (20%), Positives = 153/451 (33%), Gaps = 49/451 (10%)

Query: 1199 KSSGPPGMSSQKRYGPP-------------HETDGHGLAEATQSSKPGSVMLRLPGQEDH 1245
            +  GPPG+S Q   G P              +  G G  E T+  +    +L+     D 
Sbjct: 138  REPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTG-PEDTEGGRHAPELLKHQLLGDL 196

Query: 1246 SSQNPLIMRRRVRSFISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHS 1305
              + P +     +          + +DV  SS +D      S    A  A +     + +
Sbjct: 197  HQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQD------SPPSKASPAQDGRPPQTAA 250

Query: 1306 QDIKSIPKRDSSKDLPSPD------SRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKI 1359
            ++  SIP   +   +P P       S   PA     P+  +     KG+   LE      
Sbjct: 251  REATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRA----KGQDAPLEFTFHVE 306

Query: 1360 TSPNIRRSASSNSAEAGGDTVTLDDILSLKS-GPPEGGSVAVQDADIEKRKGEVASDLVS 1418
             +PN+++  + +    G            ++ GP  G      D      K   A+    
Sbjct: 307  ITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK 366

Query: 1419 PANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGR 1478
            P ++   ++  +   S++  GS D K KT T +   T    P     S     PGS+   
Sbjct: 367  PVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRP---CLSPKHPTPGSS--- 420

Query: 1479 PDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGK 1538
             D  +  ++P + P+  + P            +  KE        K +   P+G  P G+
Sbjct: 421  -DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQ 479

Query: 1539 KKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKT 1598
            K     G  N  +   + PP P  PP      + GEP     R           P  R  
Sbjct: 480  K-----GQANATRIPAKTPPAPKTPP------SSGEPPKSGDRSGYSSPGSPGTPGSRSR 528

Query: 1599 KQAVPIVEPQEPEIKLKYATQPLDKTDAKNK 1629
              ++P    +EP+      T P   + AK++
Sbjct: 529  TPSLPTPPTREPKKVAVVRTPPKSPSSAKSR 559



 Score = 32.0 bits (71), Expect = 6.1
 Identities = 57/273 (20%), Positives = 92/273 (33%), Gaps = 64/273 (23%)

Query: 483 KKTSKRPSSSKKADSCTNSEGSSQPEE------------QLKSPMAESLDGGCSSSSEDQ 530
           K +++ P+S     S   ++G   P E            + ++   E L       +  +
Sbjct: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE 333

Query: 531 GERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEP----PRLNASPAAREEATSPGA 586
           G   R   G S   DT  +    E +   PA   + +P    P+L A   ++       +
Sbjct: 334 GPEAR---GPSLGEDTK-EADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSK-------S 382

Query: 587 KDMPLSSDGNPKVNEKTVG-VIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPS----- 640
           KD   S D   K + ++    + +R  ++ +   PG  D   Q   PA    PPS     
Sbjct: 383 KDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHV 442

Query: 641 --------NGGAKE------TSHASLPQPEPPGGGGSKGNKNGDN-------------NS 673
                   + GAKE           +  P      G KG  N                +S
Sbjct: 443 SSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 502

Query: 674 NHNGEGNGQSGHSAAG----PGFTSRTEPSKSP 702
               +   +SG+S+ G    PG  SRT    +P
Sbjct: 503 GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP 535


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 41/184 (22%), Positives = 75/184 (40%), Gaps = 5/184 (2%)

Query: 478 ALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQL 537
           A T ++ T K       A+     EG  +P++  +    E      +++++++  +    
Sbjct: 29  AATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPE 88

Query: 538 SGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNP 597
             +  +        A E+  ++P   A  E P+   + AA  E+ +P A + P   +G P
Sbjct: 89  KTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEP 148

Query: 598 KVNEKTVGVIVSREAMTGRV---EKPGGQDKG-SQEDDPAATQRPPSNGGAKETSHASLP 653
           K  E             G      KPG  +   S ++ PAAT+ P S   A+  + AS  
Sbjct: 149 KKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPA-ASAE 207

Query: 654 QPEP 657
           +P+P
Sbjct: 208 EPKP 211


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.126    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,314,926
Number of Sequences: 37866
Number of extensions: 5652891
Number of successful extensions: 55891
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 312
Number of HSP's successfully gapped in prelim test: 1124
Number of HSP's that attempted gapping in prelim test: 33828
Number of HSP's gapped (non-prelim): 16057
length of query: 1960
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1843
effective length of database: 13,817,196
effective search space: 25465092228
effective search space used: 25465092228
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.