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Search of human proteins with 31652242
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
(1938 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens] 3958 0.0
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens] 3947 0.0
gi|40807477 retinoic acid induced 1 [Homo sapiens] 249 2e-65
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 91 1e-17
gi|57864582 hornerin [Homo sapiens] 87 2e-16
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 86 3e-16
gi|60097902 filaggrin [Homo sapiens] 84 1e-15
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 82 5e-15
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 81 1e-14
gi|62122917 filaggrin family member 2 [Homo sapiens] 79 3e-14
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 76 3e-13
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 76 4e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 68 8e-11
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 65 6e-10
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 65 8e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 64 2e-09
gi|150378539 piccolo isoform 1 [Homo sapiens] 64 2e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 63 2e-09
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 60 2e-08
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 59 6e-08
gi|93141033 PAX interacting protein 1 [Homo sapiens] 59 6e-08
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] 59 6e-08
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 59 6e-08
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 59 6e-08
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 59 6e-08
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 59 6e-08
gi|33286444 mastermind-like 2 [Homo sapiens] 57 1e-07
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 57 2e-07
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 56 3e-07
gi|30795231 brain abundant, membrane attached signal protein 1 [... 56 3e-07
>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
Length = 1938
Score = 3958 bits (10264), Expect = 0.0
Identities = 1938/1938 (100%), Positives = 1938/1938 (100%)
Query: 1 MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 60
MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR
Sbjct: 1 MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 60
Query: 61 GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 120
GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP
Sbjct: 61 GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 120
Query: 121 PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV 180
PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV
Sbjct: 121 PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV 180
Query: 181 QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS 240
QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS
Sbjct: 181 QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS 240
Query: 241 SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF 300
SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF
Sbjct: 241 SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF 300
Query: 301 EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF 360
EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF
Sbjct: 301 EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF 360
Query: 361 HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP 420
HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP
Sbjct: 361 HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP 420
Query: 421 TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT 480
TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT
Sbjct: 421 TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT 480
Query: 481 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540
PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ
Sbjct: 481 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540
Query: 541 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600
STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN
Sbjct: 541 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600
Query: 601 EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660
EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG
Sbjct: 601 EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660
Query: 661 GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN 720
GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN
Sbjct: 661 GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN 720
Query: 721 VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG 780
VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG
Sbjct: 721 VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG 780
Query: 781 SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP 840
SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP
Sbjct: 781 SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP 840
Query: 841 IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL 900
IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL
Sbjct: 841 IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL 900
Query: 901 NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES 960
NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES
Sbjct: 901 NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES 960
Query: 961 YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP 1020
YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP
Sbjct: 961 YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP 1020
Query: 1021 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN 1080
GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN
Sbjct: 1021 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN 1080
Query: 1081 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK 1140
SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK
Sbjct: 1081 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK 1140
Query: 1141 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1200
DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS
Sbjct: 1141 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1200
Query: 1201 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF 1260
SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF
Sbjct: 1201 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF 1260
Query: 1261 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL 1320
ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL
Sbjct: 1261 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL 1320
Query: 1321 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV 1380
PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV
Sbjct: 1321 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV 1380
Query: 1381 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS 1440
TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS
Sbjct: 1381 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS 1440
Query: 1441 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV 1500
VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV
Sbjct: 1441 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV 1500
Query: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560
GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP
Sbjct: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560
Query: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620
PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP
Sbjct: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620
Query: 1621 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK 1680
LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK
Sbjct: 1621 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK 1680
Query: 1681 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK 1740
ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK
Sbjct: 1681 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK 1740
Query: 1741 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR 1800
RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR
Sbjct: 1741 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR 1800
Query: 1801 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL 1860
SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL
Sbjct: 1801 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL 1860
Query: 1861 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL 1920
WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL
Sbjct: 1861 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL 1920
Query: 1921 HEENFSVRCPKHKVRLWR 1938
HEENFSVRCPKHKVRLWR
Sbjct: 1921 HEENFSVRCPKHKVRLWR 1938
>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
Length = 1960
Score = 3947 bits (10235), Expect = 0.0
Identities = 1933/1933 (100%), Positives = 1933/1933 (100%)
Query: 1 MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 60
MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR
Sbjct: 1 MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 60
Query: 61 GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 120
GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP
Sbjct: 61 GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 120
Query: 121 PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV 180
PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV
Sbjct: 121 PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV 180
Query: 181 QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS 240
QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS
Sbjct: 181 QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS 240
Query: 241 SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF 300
SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF
Sbjct: 241 SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF 300
Query: 301 EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF 360
EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF
Sbjct: 301 EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF 360
Query: 361 HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP 420
HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP
Sbjct: 361 HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP 420
Query: 421 TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT 480
TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT
Sbjct: 421 TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT 480
Query: 481 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540
PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ
Sbjct: 481 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540
Query: 541 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600
STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN
Sbjct: 541 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600
Query: 601 EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660
EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG
Sbjct: 601 EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660
Query: 661 GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN 720
GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN
Sbjct: 661 GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN 720
Query: 721 VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG 780
VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG
Sbjct: 721 VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG 780
Query: 781 SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP 840
SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP
Sbjct: 781 SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP 840
Query: 841 IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL 900
IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL
Sbjct: 841 IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL 900
Query: 901 NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES 960
NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES
Sbjct: 901 NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES 960
Query: 961 YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP 1020
YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP
Sbjct: 961 YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP 1020
Query: 1021 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN 1080
GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN
Sbjct: 1021 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN 1080
Query: 1081 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK 1140
SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK
Sbjct: 1081 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK 1140
Query: 1141 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1200
DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS
Sbjct: 1141 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1200
Query: 1201 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF 1260
SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF
Sbjct: 1201 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF 1260
Query: 1261 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL 1320
ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL
Sbjct: 1261 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL 1320
Query: 1321 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV 1380
PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV
Sbjct: 1321 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV 1380
Query: 1381 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS 1440
TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS
Sbjct: 1381 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS 1440
Query: 1441 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV 1500
VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV
Sbjct: 1441 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV 1500
Query: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560
GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP
Sbjct: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560
Query: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620
PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP
Sbjct: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620
Query: 1621 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK 1680
LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK
Sbjct: 1621 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK 1680
Query: 1681 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK 1740
ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK
Sbjct: 1681 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK 1740
Query: 1741 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR 1800
RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR
Sbjct: 1741 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR 1800
Query: 1801 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL 1860
SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL
Sbjct: 1801 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL 1860
Query: 1861 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL 1920
WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL
Sbjct: 1861 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL 1920
Query: 1921 HEENFSVRCPKHK 1933
HEENFSVRCPKHK
Sbjct: 1921 HEENFSVRCPKHK 1933
>gi|40807477 retinoic acid induced 1 [Homo sapiens]
Length = 1906
Score = 249 bits (636), Expect = 2e-65
Identities = 226/801 (28%), Positives = 351/801 (43%), Gaps = 114/801 (14%)
Query: 1192 SRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLP--GQEDHSSQN 1249
S++ P++ P +++K H ++ + Q S R+P G S
Sbjct: 1158 SKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDR 1217
Query: 1250 PLIMRRRVRSFISPIPSKRQSQDVKNSSTEDK------GRLLHSSKEGADKAFNSYAHLS 1303
PL +R +F++P+P+K+++ +++ S+ G EG+ F +
Sbjct: 1218 PLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERPEGSPTLFKRMSSPK 1277
Query: 1304 HSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTSPA------KTKILPPRKGRGLKLEAIVQ 1357
++ K + + LP P++ + + L S A KTK+LPPRKGRGLKLEAIVQ
Sbjct: 1278 KAKPTKG--NGEPATKLPPPETPDA-CLKLASRAAFQGAMKTKVLPPRKGRGLKLEAIVQ 1334
Query: 1358 KITSPNIRRSASSNSAEAGGDTVT-----LDDILSLKSGPPEGGSVAVQDADIEKRKGEV 1412
KITSP++++ A + G+ ++ D L G P G + + ++
Sbjct: 1335 KITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEGLVNVGTGQKLPTS 1394
Query: 1413 ASDLV--SPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQ 1470
+D + +P N+ L + + S D KTE A T +P G + +
Sbjct: 1395 GADPLCRNPTNRSLK-----GKLMNSKKLSSTDCFKTE--AFTSPEALQPGG---TALAP 1444
Query: 1471 KPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPP 1530
K S +GR PL + P +L P ++ + T S G
Sbjct: 1445 KKRSRKGRAGAHGLSKGPL--EKRPYLGPALLLTP------RDRASGTQGASEDNSGGGG 1496
Query: 1531 KGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQI----PEGSADGEPKPKKQRQRRER 1586
K K K +G + QPP P PQ G + K++R R R
Sbjct: 1497 K------KPKMEELGLAS------QPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGR 1544
Query: 1587 RK-----PGAQPRKRKTKQAVPIVEPQEPEIKLKYATQ-PLDKTDAKNKSFYPYIHVVNK 1640
K P KR+ +Q V ++P EPEI+LKY + ++D++ +F P++ V +
Sbjct: 1545 AKNTTSSPCKGRAKRRRQQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFSPFVRVEKR 1604
Query: 1641 CELGAVCTIIN----------------AEEEEQTKLVRGRKGQRSLTPPPSS--TESKAL 1682
+CT++N + + G T P S +L
Sbjct: 1605 DAFTTICTVVNSPGDAPKPHRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQPRPSL 1664
Query: 1683 PASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPKRA 1742
P SS M GPVV+++ LVCCLC A+++++GDL GP+YP+ LPK P
Sbjct: 1665 PLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYYPEH---CLPKKKP---- 1717
Query: 1743 TEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCG--GGPR 1800
K++ K G+ + E+ + E + A + R D G R
Sbjct: 1718 -------KLKEKVRPEGTCEEASLPLERTLKGPECAAAATAGKPPRPDGPADPAKQGPLR 1770
Query: 1801 SLSRGLP-------CKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELP-LDSNEF 1852
+ +RGL C +G E + P E + P P ++ E
Sbjct: 1771 TSARGLSRRLQSCYCCDGREDGGEE--------AAPADKGRKHECSKEAPAEPGGEAQEH 1822
Query: 1853 WVHEGCILWANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPC 1912
WVHE C +W G+YLV G+L+GLQEA+++A +M CS CQEAGAT+GC +KGC YHYPC
Sbjct: 1823 WVHEACAVWTGGVYLVAGKLFGLQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYPC 1882
Query: 1913 AIDADCLLHEENFSVRCPKHK 1933
A DA C+ EENFS++CPKHK
Sbjct: 1883 ASDAGCIFIEENFSLKCPKHK 1903
Score = 181 bits (459), Expect = 6e-45
Identities = 197/627 (31%), Positives = 270/627 (43%), Gaps = 91/627 (14%)
Query: 1 MQSFREQSSYHGNQQSYPQEVHGSSRLEEF-SPRQA------QMFQNFGGTGGSSGSSGS 53
MQSFRE+ +HG QQ+Y Q +SRLE + P QA Q S
Sbjct: 1 MQSFRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYE 60
Query: 54 GSGGGRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSG 113
G G G AAA AA D Y+ P T Q Q RP+
Sbjct: 61 GGAGTPSGTAAAVAA-------------------DKYHRGSKALP----TQQGLQGRPAF 97
Query: 114 PVQSYGPPQGSSFGNQYGSEGHVGQFQA------QHSGL-GGVSHYQQDYTGPFS-PGSA 165
P YG S + +Y E + + A Q L GV+ Y ++ + P S
Sbjct: 98 P--GYGVQDSSPYPGRYAGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSR 155
Query: 166 QYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
QY +Q + QV L+ P PQ QP + +QR A+
Sbjct: 156 QYAEQGA------QVPFRTHSLHVQQPPPPQ---QPLAYPK----LQRQKLQNDIASPLP 202
Query: 226 LRVG-QFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAY 284
G F QH QS +SS+ SS S Q Q SY S ++ S++ A
Sbjct: 203 FPQGTHFPQHSQSFPTSSTYSS--SVQGGGQGAHSYK-SCTAPTAQPHDRPLTASSSLAP 259
Query: 285 G--TQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQS 342
G Q+ ++YQ + +Q Q QQ QQQQQ Q +H +Q + Y N A K
Sbjct: 260 GQRVQNLHAYQSGRLSYDQQQ---QQQQQQQQQQQALQSRHHAQETLHYQNLA-KYQHYG 315
Query: 343 QVGQ-YNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ- 400
Q GQ Y QP+ VR+P Q++Q FSP S+ SPA SV +SPS SSTPSPLM EN Q
Sbjct: 316 QQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQ 375
Query: 401 ----GSVPMGSRNRILQLMPQLSPTPS-MMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSS 455
G+ P G + MP L+P+P+ S ++ A K + +PE L+D L S
Sbjct: 376 PLSTGAFPAGITDH-SHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQS 434
Query: 456 LSALSTQVANLPNTVQHMLLSDALTPQKKTSK----RPSSSKKADSCTNSEGSSQPEEQL 511
L+AL++QV N+ NTVQ +LLS A PQKK K R K+ C + EGS E
Sbjct: 435 LTALTSQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHC-SPEGSGYSAEPA 493
Query: 512 KSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRL 571
+P++E S+ + + LSG + ++ A+ P R+
Sbjct: 494 GTPLSEP-PSSTPQSTHAEPQEADYLSGSEDPLERSF----------LYCNQARGSPARV 542
Query: 572 NASPAAREEATS----PGAKDMPLSSD 594
N++ A+ E+ S DM SD
Sbjct: 543 NSNSKAKPESVSTCSVTSPDDMSTKSD 569
Score = 37.4 bits (85), Expect = 0.14
Identities = 45/179 (25%), Positives = 65/179 (36%), Gaps = 14/179 (7%)
Query: 1523 PKQEG------FPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPK 1576
P Q+G FP G S GR G + Q P PPPPQP +P G A +
Sbjct: 86 PTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQA-WGAPQPPPPQPQPLPAGVAKYDEN 144
Query: 1577 PKKQR---QRRERRKPGAQ-PRKRKTKQAVPIVEPQEPEIKLKYATQPLDKTDAKNKSFY 1632
K+ R+ + GAQ P + + PQ+P K Q L A F
Sbjct: 145 LMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFP 204
Query: 1633 PYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQG 1691
H + + ++ + +G +S T P + + L ASS + G
Sbjct: 205 QGTHFPQHSQSFPTSSTYSSSVQGGG---QGAHSYKSCTAPTAQPHDRPLTASSSLAPG 260
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 90.5 bits (223), Expect = 1e-17
Identities = 271/1272 (21%), Positives = 408/1272 (32%), Gaps = 213/1272 (16%)
Query: 6 EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAA 65
+ +SY+ N+ +YP + SPR GG+ GS + + G + +++
Sbjct: 211 QYNSYYPNRSAYPPPAPAYALS---SPR-----------GGTPGSGAAAAAGSKPPPSSS 256
Query: 66 AAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQ--RRPSGPVQSYGPPQG 123
A+A +S +S Q Q F G AG P T TP Q PS G P G
Sbjct: 257 ASASSSSSSFAQ--QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGG 314
Query: 124 S-SFGNQYGSEGH------------VGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQ 170
S G Q G G A + GG Q+ + P SPGS+ Q
Sbjct: 315 DYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQ--QRSHHAPMSPGSSGGGGQ 372
Query: 171 ASSQQQQ-----QQVQQLRQQLYQSHQPLPQATGQPAS-SSSHLQP-----MQRPSTLPS 219
++ Q Q+ ++R Q Y P Q G P+ H P Q P P
Sbjct: 373 PLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPM 432
Query: 220 SAAG----------YQLRVGQFGQHYQSSASSSSSSSF-----PSPQRFSQSGQSYDGSY 264
+ G Y ++ +GQ S + + P PQ+ S
Sbjct: 433 TMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQ 492
Query: 265 NVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHP 324
+A Y+ Q +Q YS QP S +Q+ P +QQ QQ PQ Q
Sbjct: 493 TPHAQPSYQQQPQSQPPQLQSSQPPYSQQP-SQPPHQQSPAPYPSQQSTTQQHPQSQPPY 551
Query: 325 SQHVMQ--YTNAATKLPLQSQVGQ---YNQPEVPVRSPMQFHQNFSP----ISNPSPAAS 375
SQ Q Y + P S + Q Y QP+ + Q P +S S +
Sbjct: 552 SQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQ 611
Query: 376 VVQSPSCSSTPSPLMQTGENLQCGQGSVP-MGSRNRILQLMPQLSPTPSMMPSPNSHAAG 434
+PS +S+ +LQ S+P + L + + + +P + S S + G
Sbjct: 612 ASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQG 671
Query: 435 FKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHML---LSDALTPQKKTSKRPSS 491
+ + P T P L + S P +V LS A P + RP S
Sbjct: 672 EQSNPAQS-PFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPS 730
Query: 492 ---------SKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSG--- 539
S S G Q Q+ + G S + G ++ G
Sbjct: 731 GQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ-YSSPQPGSALSPRQPSGGQIHTGMGSYQ 789
Query: 540 QSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP-GAKDMPLSSDGNPK 598
Q++ +GG G P Q N P N A +P GA G P
Sbjct: 790 QNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPP 849
Query: 599 VNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLP----- 653
G R + +P G + + + PP G ++T ++
Sbjct: 850 YGTLPPG----RMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAA 905
Query: 654 ---QPEPPG-----GGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSL 705
Q PPG GG G G GQ +S AG + P G++
Sbjct: 906 NSIQNRPPGYPNMNQGGMMG----------TGPPYGQGINSMAGM-INPQGPPYSMGGTM 954
Query: 706 RYSYKDSFGSAVPRNVSGFPQYPTG-----QEKGDFTGHGERKGRNEKFPSLLQEVLQGY 760
+S G A + G K D T E K + + E +
Sbjct: 955 A---NNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKL 1011
Query: 761 HH---HPDR-----RYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGSLL 812
+ P+R RY T+E G T + + +L + K IG L
Sbjct: 1012 YELGGEPERKMWVDRYLAFTEE------KAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLT 1065
Query: 813 ENPHWGPWER--------KSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERR 864
+ W SSS A +K+ + FE + + P +
Sbjct: 1066 QVNKNKKWRELATNLNVGTSSSAASSLKKQYI---QCLYAFECKIERGEDPPPDIFA--- 1119
Query: 865 SVICDISPLRQIVRDPGAHSLGHM-------SADTRIGRNDRLNPTL------SQSVILP 911
D + ++ P G M S + + L P SQ LP
Sbjct: 1120 --AADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLP 1177
Query: 912 GGLVSMETKLKSQSGQIKEEDFEQSKSQASF--NNKKSGDHCHPPSIKHESYRGNASPGA 969
G S+S + +D S ++F N + + + PS+ G S
Sbjct: 1178 G---------MSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMS--- 1225
Query: 970 ATHDSLSDYGPQDSRPTPMRRVPGR---VGGREGMRGRSPSQYHDFAEKLKMSPGRSRGP 1026
Y P MR+ PG + +G G Y R+ GP
Sbjct: 1226 --------YEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY-----------SRAAGP 1266
Query: 1027 GGDPHHMNP--HMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLH 1084
G M P H + +R P A N +P++G+ S
Sbjct: 1267 GLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMP---SNPDSGMYSPSR 1323
Query: 1085 YKRQMYQQQPEEYKDWSSG-SAQGVIAAAQHRQEGPRKSPRQQQF----LDRVRSPLKND 1139
Y Q QQQ + + + + S QG + + + +QQQ +D P
Sbjct: 1324 YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKR 1383
Query: 1140 KDGMMYGPPVGT 1151
+G MY P T
Sbjct: 1384 HEGEMYSVPYST 1395
Score = 51.2 bits (121), Expect = 1e-05
Identities = 94/408 (23%), Positives = 147/408 (36%), Gaps = 86/408 (21%)
Query: 50 SSGSGSGGGR-----RGAAAAAAAMASETSGHQGYQG----FRKEAGDFYYMAGNKDPVT 100
SSG G GG R A +A H Y G R E G G + ++
Sbjct: 1247 SSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPG-----IGPEGNMS 1301
Query: 101 TGTPQP---PQRRPSGPVQ-SYGPPQGS--------SFGNQYGSEG----------HVGQ 138
TG PQP P SG S PPQ S+GNQ+ ++G
Sbjct: 1302 TGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTM 1361
Query: 139 FQAQHS----------GLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLY 188
+Q Q G H + Y+ P+S G Q QQQ Q Q Q
Sbjct: 1362 YQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQ-----Q 1416
Query: 189 QSHQPLPQ-------ATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASS 241
Q+ QP PQ PA++++ + +RP+ P + + QFG+ S+
Sbjct: 1417 QAAQPSPQQDVYNQYGNAYPATATAATE--RRPAGGPQNQFPF-----QFGRDRVSAPPG 1469
Query: 242 SSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSY-QPQSMKNF 300
+++ PQ G + G+ ++G N Y+Y QS +
Sbjct: 1470 TNAQQNMPPQ--MMGGPIQASAEVAQQGTMWQGRN----------DMTYNYANRQSTGSA 1517
Query: 301 EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLP---LQSQVGQYNQPEVPVRSP 357
Q G + + Q+ + H + + T+ P + V +P P
Sbjct: 1518 PQGPAYHGVNRTDEMLHTDQR---ANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQP 1574
Query: 358 MQFHQNFSP-ISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVP 404
QN P +S+P+P +++ + S + SP + +G +Q VP
Sbjct: 1575 PPSMQNHIPQVSSPAPLPRPMENRT-SPSKSPFLHSGMKMQKAGPPVP 1621
Score = 50.8 bits (120), Expect = 1e-05
Identities = 163/799 (20%), Positives = 263/799 (32%), Gaps = 95/799 (11%)
Query: 39 QNFGGTGGSSGSSGSGSGGG---------RRGAAAAAAAMASETSGHQGYQGFRKEAG-- 87
Q+ + G G G+GSGGG G A A+ + + G G G
Sbjct: 74 QDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133
Query: 88 -DFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGL 146
+ A P G QP R PS + + F Q+G + G Q G
Sbjct: 134 APPHSAAAALPPPAYGFGQPYGRSPS----AVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189
Query: 147 GGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSS 206
GG+ Y G +Q + + S + +G A++ S
Sbjct: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGS 249
Query: 207 HLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQ-----RFSQSGQSYD 261
P S SS++ Q R G G S+A + +P S + Y
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309
Query: 262 G--SYNVNAGSQYEGHNVG---SNAQAYGTQSNYSYQPQSMKNFEQ----AKIPQGTQQG 312
G + + G Q G G +Q +G + + + +Q A + G+ G
Sbjct: 310 GYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG 369
Query: 313 QQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVG--QYNQPEVPVRSPMQFH--------- 361
Q + Q PS + Q K+ Q G Y+Q + P P Q H
Sbjct: 370 GGQPLARTPQ-PSSPMDQ----MGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGS 424
Query: 362 ---QNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRN--RILQLMP 416
Q + P++ A S + S + P Q G + QG P ++ Q P
Sbjct: 425 QTPQRY-PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQP 483
Query: 417 QLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHML-- 474
S P PS HA + P+ + P L S +Q + P Q
Sbjct: 484 PYSQQP---PSQTPHAQP----SYQQQPQSQ--PPQLQSSQPPYSQQPSQPPHQQSPAPY 534
Query: 475 -LSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGER 533
+ T Q S+ P S +A S + QP S A S + +
Sbjct: 535 PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQ 594
Query: 534 VRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSS 593
R Q S D+ +S + +S G ++ L + P++ + S D+P+ +
Sbjct: 595 QRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPD-LSGSIDDLPMGT 653
Query: 594 DGNPKVNEKTVGVIVSREAMTGRVEKPGGQD-----KGSQEDDPAATQRPPSNGGAKE-- 646
+G T G+ S+ + + P G + P+ P S ++
Sbjct: 654 EGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGP 713
Query: 647 TSHASLP---QPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPG 703
S A++P P P G S + N + + G + P ++ S PG
Sbjct: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYS-----SPQPG 768
Query: 704 SLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHH 763
S S + G + + + Q G + G + G +P Y+
Sbjct: 769 S-ALSPRQPSGGQIHTGMGSYQQ----NSMGSYGPQGGQYGPQGGYPR-----QPNYNAL 818
Query: 764 PDRRYSRSTQEHQGMAGSL 782
P+ Y + GMAG +
Sbjct: 819 PNANYPSA-----GMAGGI 832
Score = 32.3 bits (72), Expect = 4.6
Identities = 66/292 (22%), Positives = 100/292 (34%), Gaps = 54/292 (18%)
Query: 1357 QKITSPNIRRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKR------KG 1410
Q +TSP+ SA GGD SG P+ G AD+ +
Sbjct: 297 QLLTSPS---SARGYQGYPGGDY----------SGGPQDGGAGKGPADMASQCWGAAAAA 343
Query: 1411 EVASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQ 1470
A+ A Q H P SS + + + + + + P T+ SQ
Sbjct: 344 AAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ 403
Query: 1471 KPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVT--ISPKQEGF 1528
+ QG P G G +P P G P+ P + + +S Q+
Sbjct: 404 Q----QGPPSGPQQGHG---YPGQ----PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQ-I 451
Query: 1529 PPKGYF-PSGKKKGRPIGSVNKQK---KQQQPPPPPPQPPQIPEGSADGEPKPKKQ---- 1580
PP G PSG + N+Q +QQQPP P Q P + +P+ Q
Sbjct: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511
Query: 1581 -----------RQRRERRKPGAQPRKRKTKQAVPIVEP--QEPEIKLKYATQ 1619
Q ++ P P ++ T Q P +P +P+ + Y Q
Sbjct: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQ 563
Score = 32.3 bits (72), Expect = 4.6
Identities = 37/156 (23%), Positives = 59/156 (37%), Gaps = 44/156 (28%)
Query: 1465 TSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPK 1524
+ T + P + QGR ++GG + ++ +PP G
Sbjct: 424 SQTPQRYPMTMQGRAQSAMGGLSY-----TQQIPPYG----------------------- 455
Query: 1525 QEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRR 1584
Q+G P GY G++ P + QQQ PP QPP S +P Q+Q
Sbjct: 456 QQG--PSGY---GQQGQTPYYNQQSPHPQQQQPPYSQQPP-----SQTPHAQPSYQQQ-- 503
Query: 1585 ERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620
P +QP + ++ Q +P +P + A P
Sbjct: 504 ----PQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP 535
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 86.7 bits (213), Expect = 2e-16
Identities = 293/1329 (22%), Positives = 430/1329 (32%), Gaps = 195/1329 (14%)
Query: 8 SSY--HGNQ--QSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGR---- 59
SSY HG++ QS E HGSS S + Q+ G+ S G GSG G+
Sbjct: 955 SSYEQHGSRSGQSSRSEQHGSS-----SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1009
Query: 60 -RGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSY 118
RG + + +S ++ G+ G + +G+ ++G R SG Y
Sbjct: 1010 SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGH----SSGLGHRESR--SGQSSGY 1063
Query: 119 GPPQGSSFGNQYGSEGHVGQFQAQHSGLG--GVSHYQQDYTGPFSPGSAQ---YQQQASS 173
G GSS G+ + G G Q S G G S Q G GS+Q Y +Q S
Sbjct: 1064 GQ-HGSSSGHS-STHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1121
Query: 174 QQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQ 233
Q Q QS +G SSSS Q S L S+ FG
Sbjct: 1122 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG----QHGSGLGESSG--------FGH 1169
Query: 234 HYQSSASSSSSSSFPSPQRFSQSGQSYD-GSYNVNAGSQYEGHNVGSNAQAYGTQSNYSY 292
H SS SSS S Q S SG S G + +G G GS++ G+ S+Y
Sbjct: 1170 HESSSGQSSSYS-----QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSS---GSSSHYGQ 1221
Query: 293 QPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQ 343
+ G Q P + +H S QH ++++ P +S+
Sbjct: 1222 HGSGSRQ----SSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 1277
Query: 344 VGQ---YNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ 400
G + Q E + Q+ S S Q S S S Q G +
Sbjct: 1278 SGHSSVFGQHESGSGHSSAYSQHG---SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 1334
Query: 401 GSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAG---FKGFGLEGVPEKRLTDPGLSSLS 457
GS + + PS H +G +G G + G SS S
Sbjct: 1335 SYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHG------SGSGWSSSS 1388
Query: 458 ALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCT---NSEGSSQPEEQLKSP 514
+ + H SSS ++ CT + G S EQ S
Sbjct: 1389 GRHGSGSGQSSGFGH---------------HESSSWQSSGCTQHGSGSGHSSSYEQHGSR 1433
Query: 515 MAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNAS 574
+S G SS Q S S + G+ SP++G + S
Sbjct: 1434 SGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR-------HGS 1486
Query: 575 PAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKG-SQEDDPA 633
+ + + SP SS P + S + G E GQ G Q +
Sbjct: 1487 GSGQSSSYSPYGSGSGWSSSRGPYESGS------SHSSGLGHRESRSGQSSGYGQHGSSS 1540
Query: 634 ATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNS-----NHNGEGNGQS-GHSA 687
G+ +S Q G S ++G +S G G+GQS GH
Sbjct: 1541 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1600
Query: 688 AGPGFTSRTEPS---KSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ-EKGDFTGHGERK 743
G G SR PS GS R S GS + + SGF + + + ++ HG
Sbjct: 1601 RGSG--SRQSPSYGRHGSGSGRSSSSGQHGSGLGES-SGFGHHESSSGQSSSYSQHGSGS 1657
Query: 744 GRNEKF---PSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELAS 800
G + + S + +G H R S +H + G R S + + S
Sbjct: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQG---SGSGQSPS 1714
Query: 801 RGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPG--- 857
RG +G + G +SSS P + + F S H
Sbjct: 1715 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV-----FGQHESGSGHSSAYSQ 1769
Query: 858 --------------GSLSERRSVICDISPLRQIVRDPGAHSLGHMSADT--RIGRNDRLN 901
GS S + S G H G + + + G +
Sbjct: 1770 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 1829
Query: 902 PTLSQSVILPG------------GLVSMETKLKSQSGQIKEEDFEQSKS--QASFNNKKS 947
P+ + G G S + S SGQ +S S + + S
Sbjct: 1830 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGS 1889
Query: 948 GDHCHPPSIKHESYRGNASPG---AATHDSLSDYGPQDS----------RPTPMRRVPGR 994
G +H S G +S G ++ S S YG S + + P
Sbjct: 1890 GSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1949
Query: 995 VGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHH--MNPHMTFSERANRSSLHTPF 1052
GR G S Y + S R G H + + S +++ H
Sbjct: 1950 SRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSS 2009
Query: 1053 SPNSETLASAYHANTRAHAYGDPNAGL-NSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAA 1111
S +S T A+ ++ + G A S H + Q Y SGS Q +
Sbjct: 2010 SGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ----S 2065
Query: 1112 AQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGT-----YHDPSAQEAGRCLMS 1166
H Q G RQ R S +GP +G +H+ S+ ++
Sbjct: 2066 PGHGQRG--SGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQH 2123
Query: 1167 SDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSS-GPPGMSSQKRYGPPHETDGHGLAE 1225
G + +HGS+ Q S + +S + S G G S++ G H G G
Sbjct: 2124 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG--HGRQGSGSGH 2181
Query: 1226 ATQSSKPGS 1234
+ + GS
Sbjct: 2182 SPSRGRHGS 2190
Score = 84.7 bits (208), Expect = 8e-16
Identities = 297/1345 (22%), Positives = 433/1345 (32%), Gaps = 201/1345 (14%)
Query: 8 SSY--HGNQ--QSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGR---- 59
SSY HG++ QS E HGSS S + Q+ G+ S G GSG G+
Sbjct: 1425 SSYEQHGSRSGQSSRGERHGSS-----SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1479
Query: 60 -RGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSY 118
RG + + +S S + G+ G Y +G+ G R S QS
Sbjct: 1480 SRGRHGSGSGQSSSYSPYGSGSGWSSSRGP--YESGSSHSSGLG------HRESRSGQSS 1531
Query: 119 GPPQGSSFGNQYGSEGHVGQFQAQHSGLG--GVSHYQQDYTGPFSPGSAQ---YQQQASS 173
G Q S + G G Q S G G S Q G GS+Q Y +Q S
Sbjct: 1532 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1591
Query: 174 QQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQ 233
Q Q QS +G SSSS Q S L S+ FG
Sbjct: 1592 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG----QHGSGLGESSG--------FGH 1639
Query: 234 HYQSSASSSSSSSFPSPQRFSQSGQSYD-GSYNVNAGSQYEGHNVGSNAQA---YGTQSN 289
H SS SSS S Q S SG S G + +G G GS++++ YG +
Sbjct: 1640 HESSSGQSSSYS-----QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS 1694
Query: 290 YSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPL 340
S Q G Q Q P + +H S QH ++++ P
Sbjct: 1695 GSRQSSG----------HGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 1744
Query: 341 QSQVGQ---YNQPEVPVRSPMQFHQNFSP----ISNPSPAASVVQSPSCSSTPSPLMQTG 393
+S+ G + Q E + Q+ S S ++ QS + S Q+
Sbjct: 1745 ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 1804
Query: 394 ENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGF----KGFGLEGVPEKRLT 449
+ Q G GS S + Q SP+ S + H++ + G G + +
Sbjct: 1805 SHGQHGSGSSQSSSYGQQGSGSGQ-SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 1863
Query: 450 DPGLSS-LSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPE 508
G SS + QH S + ++ R S + + +S GSS
Sbjct: 1864 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSY 1923
Query: 509 EQLKSPMAESLDGGCSSSSEDQG---ERVRQLSGQSTSSDTTYKGGASE--------KAG 557
Q S +SL G S Q R R SG SS G S ++G
Sbjct: 1924 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESG 1983
Query: 558 SSPAQGAQNEPPRLNASPAAREEATSPG------------AKDMPLSSDGNPKVNEKTVG 605
S + G + R S + +S G + G + G
Sbjct: 1984 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHG 2043
Query: 606 VIVSREAMT---GRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGG 662
S + + GR GQ G + + Q P + +S PG G
Sbjct: 2044 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGE 2103
Query: 663 SKG-----NKNGDNNS-NHNGEGNGQS---GHSAAGPGFTSRTE--PSKSPGSLRYSYKD 711
S G + +G ++S + +G G+G S G + G +SR E S S S RY
Sbjct: 2104 SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHG 2163
Query: 712 S---FGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRY 768
S S R SG P+ G +GH G++ G R
Sbjct: 2164 SGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHG----------SGSGRSSSRGP 2213
Query: 769 SRSTQEHQGMAGSLEGTTRPNVLVSQ----TNELASRGLLNKSIGSLLENPHWGPWERKS 824
S H + G E + + SQ + S+G + G ++++
Sbjct: 2214 YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS------STFDQEG 2267
Query: 825 SSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAH- 883
SST QSS+H GS S + S G H
Sbjct: 2268 SSTG---------------------QSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 2306
Query: 884 -SLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKS--QA 940
GH S+ + G G S + S SGQ +S S +
Sbjct: 2307 SGSGHSSSYGQHGSG--------------SGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
Query: 941 SFNNKKSGDHCHPPSIKHESYRGNASPG---AATHDSLSDYGPQDS----------RPTP 987
+ SG +H S G +S G ++ S S YG S +
Sbjct: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
Query: 988 MRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSS 1047
+ P GR G S Y + S R G H S S
Sbjct: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
Query: 1048 LHTPFSPNSETLASAYHANTRAHAYGDPNAGLN---SQLHYKRQMYQQQPEEYKDWSSGS 1104
S + + H +T + G + S H + Q Y SGS
Sbjct: 2473 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2532
Query: 1105 AQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVG-TYHDPSAQEAGRC 1163
Q R G R+SP + + + G G G +H+ S+ ++
Sbjct: 2533 GQS--PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSY 2590
Query: 1164 LMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSS-GPPGMSSQKRYGPPHETDGHG 1222
G + +HGS+ Q S + +S + S G G S++ G H G G
Sbjct: 2591 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG--HGRQGSG 2648
Query: 1223 LAEATQSSKPGSVMLRLPGQEDHSS 1247
++ + GS + H S
Sbjct: 2649 SGQSPSRGRHGSGLGHSSSHGQHGS 2673
Score = 83.2 bits (204), Expect = 2e-15
Identities = 292/1384 (21%), Positives = 436/1384 (31%), Gaps = 201/1384 (14%)
Query: 3 SFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGA 62
S+ QSS +G Q S + G + S + Q+ G+G SS + GSG G+
Sbjct: 171 SYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSG 230
Query: 63 AAAAAAMASETSGH----------QGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPS 112
+ + + ++SG+ GY +G G + ++G+ + S
Sbjct: 231 FSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQ--SSRGERHRSSSGSSSSYGQHGS 288
Query: 113 GPVQSYGPPQ----------------GSSFGNQYG----------SEGHVGQFQAQHSGL 146
G QS G + GS + +G S GH Q SG
Sbjct: 289 GSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGF 348
Query: 147 G-------------------GVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQL 187
G G S Q + S+ Q +SS+Q Q
Sbjct: 349 GQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASR 408
Query: 188 YQS--------------HQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQ 233
+ S H +GQ SS H R S+ +G G FG
Sbjct: 409 HSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSG-FGH 467
Query: 234 HYQSSASSSSSSSFPSPQRFSQSGQSY-DGSYNVNAGSQYEGHNVGSNAQAYGTQSNY-S 291
H SS SS + Q S SG S G + +G G GS+A G+ S+Y
Sbjct: 468 HESSSEHSSGYT-----QHGSGSGHSSGHGQHGSRSGQSSRGERQGSSA---GSSSSYGQ 519
Query: 292 YQPQSMKNFEQAKIPQGTQQ------GQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVG 345
+ S ++ ++ G+ Q G+ + +Q H ++++ P +S G
Sbjct: 520 HGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSG 579
Query: 346 Q---YNQPEVPVRSPMQFHQNFSPISNPSP----AASVVQSPSCSSTPSPLMQTGENLQC 398
E + Q+ S + S ++ QS SC + Q+ + Q
Sbjct: 580 HSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQH 639
Query: 399 GQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGF---KGFGLEGVPEKRLTDPGLSS 455
G GS SR Q PS H + F +G G + G SS
Sbjct: 640 GSGS-SQSSR------YGQQGSGSGQSPSRGRHGSDFGHSSSYGQHG------SGSGWSS 686
Query: 456 LSALSTQVANLPNTVQHML---LSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLK 512
+ V+ + H S + S S +K S S SS+ E+
Sbjct: 687 SNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGS--RSGQSSRSEQHGS 744
Query: 513 SPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLN 572
S S G S S RQ SG S G +S + S G+
Sbjct: 745 SSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTS----C 800
Query: 573 ASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDP 632
+S E+ S A G+ + G + GR GQ S + D
Sbjct: 801 SSSCGHYESGSGQASGFGQHESGSGQ-GYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDS 859
Query: 633 AATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDN-NSNHNGEGNGQS---GHSAA 688
++ Q + HAS G G G+ +G + G G+GQS G +
Sbjct: 860 SSGQSSSYGQHESASHHAS--------GRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGS 911
Query: 689 GPGFTSRT--EPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ-EKGDFTGHGERKG- 744
G G +S + S S S + +K S G + SG+ Q+ +G + HG R G
Sbjct: 912 GSGRSSSSGRHGSGSGQSSGFGHKSSSGQS-----SGYTQHGSGSGHSSSYEQHGSRSGQ 966
Query: 745 --RNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRG 802
R+E+ S H R S +H +G +R S
Sbjct: 967 SSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR--------GRHGSGS 1018
Query: 803 LLNKSIGSLLENPHW----GPWERKS--SSTAPEMKQINLTDYPIPRKFEIEPQSSAHEP 856
+ S G W GP+E S SS + + + SS H
Sbjct: 1019 GQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ 1078
Query: 857 GGSLSERRSVICDISPLRQIVRDPGAHSLG--HMSADTRIGRNDRLNPTLSQSVILPGGL 914
GS S + S G H G S R G +P Q G
Sbjct: 1079 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR-----GS 1133
Query: 915 VSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDS 974
S ++ + G + + H S + SY + S +
Sbjct: 1134 GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS--- 1190
Query: 975 LSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPH--- 1031
S YG SR R G R G S S Y + S G R G H
Sbjct: 1191 -SGYGQHGSRSGQSSR-----GERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPS 1244
Query: 1032 ---------HMNPHMTFSERANRSSLHTPF-SPNSETLASAYHANTRAHAYGDPNAGLNS 1081
H + H + RSS P+ S + + H + H+ G S
Sbjct: 1245 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 1304
Query: 1082 QLHYKRQMYQQQPEEYKDW-SSGSAQGVIAAAQHRQEGPRKSPRQ-QQFLDRVRSPLKND 1139
+ + + + GS+ G ++ HR G +S + +SP +
Sbjct: 1305 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRG- 1363
Query: 1140 KDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAK 1199
+G G +G SS G G G + S W S T
Sbjct: 1364 ----RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGS 1419
Query: 1200 SSGPPGMSSQ--KRYGPPHETDGHGLAEATQSS--KPGSVMLRLPGQEDH---SSQNPLI 1252
SG Q R G + HG + + SS + GS + G H S Q+P
Sbjct: 1420 GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1479
Query: 1253 MRRR 1256
R R
Sbjct: 1480 SRGR 1483
Score = 82.0 bits (201), Expect = 5e-15
Identities = 282/1275 (22%), Positives = 418/1275 (32%), Gaps = 214/1275 (16%)
Query: 22 HGSSRLEEFSPRQAQMF-QNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGHQGYQ 80
HGSS + S Q + ++ G G S SG G G+RG+ + S +SG G
Sbjct: 390 HGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQ----SPSSGQHG-T 444
Query: 81 GFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQGSSFGN-QYGSE-GHVGQ 138
GF + + Y++G+ G + SG Q +G G S G+ Q+GS G +
Sbjct: 445 GFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQ-HGSGSGHSSGHGQHGSRSGQSSR 503
Query: 139 FQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQAT 198
+ Q S G S Y Q +G S S + + S Q + R +
Sbjct: 504 GERQGSSAGSSSSYGQHGSG--SRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPH 561
Query: 199 GQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQ---FGQHYQSSASSSSSSSFPSPQRFSQ 255
G + SS P + S S + R GQ +GQH SS SS+ Q S
Sbjct: 562 GYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHG-----QHGST 616
Query: 256 SGQSYD-GSYNVNAG--SQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQG 312
SGQS G + +G S + H GS+ Q ++ G
Sbjct: 617 SGQSSSCGQHGATSGQSSSHGQHGSGSS--------------------------QSSRYG 650
Query: 313 QQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSP 372
QQ Q +H + ++ S GQ+ S + + P + S
Sbjct: 651 QQGSGSGQSPSRGRHGSDFGHS-------SSYGQHG-------SGSGWSSSNGPHGSVSG 696
Query: 373 AASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHA 432
+S S S S Q G G GSR+ Q + + S H
Sbjct: 697 QSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG 756
Query: 433 AGF---KGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRP 489
+G G G +G + + P+ V+H + +
Sbjct: 757 SGSHQSSGHGRQG------------------SGSGHSPSRVRH---GSSSGHSSSHGQHG 795
Query: 490 SSSKKADSCTNSE-GSSQP----EEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSS 544
S + + SC + E GS Q + + S S G S QG R SGQS+SS
Sbjct: 796 SGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQG-RHGSTSGQSSSS 854
Query: 545 DTTYKGGASEKAGSSPAQGAQNEPPRLNASPAARE---EATSPGAKDMPLSSDGNPKVNE 601
G +G S + G Q+E +AS R SPG S +P
Sbjct: 855 -----GQHDSSSGQSSSYG-QHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGR 908
Query: 602 KTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGG 661
G R + +GR GQ G + + G+ +S Q G
Sbjct: 909 HGSGS--GRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQ 966
Query: 662 GSKGNKNGDNNSN-----HNGEGNGQS-GHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGS 715
S+ ++G ++ + +G G+ QS GH G G PS+ S+G
Sbjct: 967 SSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGP 1026
Query: 716 AVPRNVSGF--PQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQ 773
R+ SG+ + P G +G G R+ R+ + GY H ST
Sbjct: 1027 Y--RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ--------SSGYGQHGSSSGHSSTH 1076
Query: 774 EHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQ 833
G S + + +S G S G + G +SS
Sbjct: 1077 GQHG---------------STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG----- 1116
Query: 834 INLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLG-HMSADT 892
R+ QS H GS S + SP S G H S
Sbjct: 1117 ---------RQGSGSGQSPGHGQRGSGSRQ-------SP-----------SYGRHGSGSG 1149
Query: 893 RIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCH 952
R + + L +S G E S SGQ +S++ SG
Sbjct: 1150 RSSSSGQHGSGLGES----SGFGHHE----SSSGQ-----------SSSYSQHGSGSGHS 1190
Query: 953 PPSIKHESYRGNASPG---AATHDSLSDYGP--QDSRPTPMRRVPGRVGGREGMRGRSPS 1007
+H S G +S G ++ S S YG SR + G G RGR S
Sbjct: 1191 SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS 1250
Query: 1008 QYHDFAEKLKMSPG----RSRGP----GGDPHHMNPHMTFSERANRSSLHTPFSPNSETL 1059
+ + G SRGP G H + S ++ S H S +
Sbjct: 1251 GLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG--SGSGHFC 1308
Query: 1060 ASAYHANTRAHAYGDPNAGLN---SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQ 1116
+ H +T + G + S + R Q Y +GS Q
Sbjct: 1309 SQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSG 1368
Query: 1117 EGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGME 1176
G S Q S G G +H+ S+ ++ C G +
Sbjct: 1369 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG-HHESSSWQSSGCTQHGSGSGHSSSY 1427
Query: 1177 LKHGSQKLQESCWDLSRQTSPAKSS-GPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSV 1235
+HGS+ Q S + +S + SS G G S++ G G G + + + GS
Sbjct: 1428 EQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS- 1486
Query: 1236 MLRLPGQEDHSSQNP 1250
G SS +P
Sbjct: 1487 -----GSGQSSSYSP 1496
Score = 71.6 bits (174), Expect = 7e-12
Identities = 277/1339 (20%), Positives = 424/1339 (31%), Gaps = 149/1339 (11%)
Query: 12 GNQQSYPQEVHGSSRLEEFSPR-----QAQMFQNFGGTGGSSGSSGSGSGGG------RR 60
G+ SY Q GS P Q+ F + G+G SSG S GSG +
Sbjct: 670 GHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKH 729
Query: 61 GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQR----RPSGPVQ 116
G+ + ++ + + G + G + + +G+ P R SG
Sbjct: 730 GSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSS 789
Query: 117 SYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQ 176
S+G Q S + S GH Q SG G H G GSA + +
Sbjct: 790 SHG--QHGSGTSCSSSCGHYESGSGQASGFG--QHESGSGQGYSQHGSASGHFSSQGRHG 845
Query: 177 QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLR---VGQ--- 230
Q + S + GQ S+S H R + + G+ R GQ
Sbjct: 846 STSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPS 905
Query: 231 FGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAG--SQYEGHNVGS----NAQAY 284
+G+H S SSSS + S SGQS + ++G S Y H GS + + +
Sbjct: 906 YGRHGSGSGRSSSSG-----RHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQH 960
Query: 285 GTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQV 344
G++S S + + + + G +Q QH S + + P + +
Sbjct: 961 GSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG------SGQSPSPSRGRH 1014
Query: 345 GQ---YNQPEVPVRSPMQFHQNFSPISNPSPAASVV-QSPSCSSTPSPLMQTGENLQCGQ 400
G + P RS + + P + S +S + S S S Q G +
Sbjct: 1015 GSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 1074
Query: 401 GSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFK---GFGLEGVPEKRLTDPGLSSLS 457
GS + Q + S H +G G+G +G + PG
Sbjct: 1075 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ--SPGHGQRG 1132
Query: 458 ALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAE 517
+ S Q P+ +H S + + S +S G S Q S
Sbjct: 1133 SGSRQS---PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1189
Query: 518 SL---DGGCSSSSEDQGERVRQLSGQST--------SSDTTYKGGASEKAGSSPAQGAQN 566
S G S +GER SG S+ S ++ G +G SP++G
Sbjct: 1190 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 1249
Query: 567 EPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPG----- 621
++S + + P S + G S + + G
Sbjct: 1250 SGLGHSSSHGQHGSGSGRSSSRGPYESRSG---HSSVFGQHESGSGHSSAYSQHGSGSGH 1306
Query: 622 ----GQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNG 677
GQ + Q S G + H + G G + +G
Sbjct: 1307 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHG 1366
Query: 678 EGNGQS---GHSAAGPGFTSRT--EPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ- 731
G+G S G +G G++S + S S S + + +S SG Q+ +G
Sbjct: 1367 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW----QSSGCTQHGSGSG 1422
Query: 732 EKGDFTGHGERKG---RNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRP 788
+ HG R G R E+ S H R S +H +G +R
Sbjct: 1423 HSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 1482
Query: 789 NVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAP----EMKQINLTDYPIPRK 844
S + + +S G GP+E SS ++ E + + Y +
Sbjct: 1483 RH-GSGSGQSSSYSPYGSGSGWSSSR---GPYESGSSHSSGLGHRESRSGQSSGYG--QH 1536
Query: 845 FEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLG--HMSADTRIGRNDRLNP 902
SS H GS S + S G H G S R G +P
Sbjct: 1537 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1596
Query: 903 TLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYR 962
Q G S ++ + G + + H S + SY
Sbjct: 1597 GHGQR-----GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1651
Query: 963 GNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGR 1022
+ S + S YG SR R G R G RS S+Y + S G
Sbjct: 1652 QHGSGSGHS----SGYGQHGSRSGQSSR-----GERHGSSSRSSSRYGQHGSGSRQSSGH 1702
Query: 1023 SR---GPGGDPH---------HMNPHMTFSERANRSSLHTPF-SPNSETLASAYHANTRA 1069
R G G P H + H + RSS P+ S + + H +
Sbjct: 1703 GRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSG 1762
Query: 1070 HA-----YGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPR 1124
H+ +G + SQ + Q + + S+G + + QH + S
Sbjct: 1763 HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS---SHGQHGSGSSQSSSY 1819
Query: 1125 QQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKL 1184
QQ +SP + +G G +G SS G G G
Sbjct: 1820 GQQGSGSGQSPSRG-----RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1874
Query: 1185 QESCWDLSRQTSPAKSSGPPGMSSQ--KRYGPPHETDGHGLAEATQSS--KPGSVMLRLP 1240
+ S W S T SG Q R G + HG + + SS + GS +
Sbjct: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSL 1934
Query: 1241 GQEDH---SSQNPLIMRRR 1256
G H S Q+P R R
Sbjct: 1935 GHGQHGSGSGQSPSPSRGR 1953
Score = 71.2 bits (173), Expect = 9e-12
Identities = 285/1330 (21%), Positives = 423/1330 (31%), Gaps = 136/1330 (10%)
Query: 7 QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSG--SSGSGSGGGRRGAAA 64
+SS G S E G E S + + Q+ G+G SSG GS SG RG
Sbjct: 1150 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 1209
Query: 65 AAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQ-SYGPPQG 123
+++ +S G G G R+ +G +G+ + G S Q G +
Sbjct: 1210 GSSSGSSSHYGQHG-SGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRS 1268
Query: 124 SSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQL 183
SS G GH F SG G S Y Q +G S Q S+ Q Q
Sbjct: 1269 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG--SGHFCSQGQHGSTSGQSSTFDQE 1326
Query: 184 RQQLYQSHQPLPQATGQPASSSSHLQPM---QRPST-LPSSAAGYQLRVGQFGQ------ 233
QS + +G SS Q PS S +G+ GQ G
Sbjct: 1327 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1386
Query: 234 ---HYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNY 290
+ S + SS + SG + GS + ++ S YE H S + G +
Sbjct: 1387 SSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSS-YEQHGSRSGQSSRGERHGS 1445
Query: 291 SYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQ--HVMQYTNAATKLPLQSQVGQYN 348
S S + Q GQ Q PS+ H +++ P S G ++
Sbjct: 1446 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG-WS 1504
Query: 349 QPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPL-----MQTGENLQCGQGSV 403
P S + S +S SS S +G++ CGQ
Sbjct: 1505 SSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1564
Query: 404 PMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFK---GFGLEGVPEKRLTDPGLSSLSALS 460
G + S H +G G+G +G + PG + S
Sbjct: 1565 SSGQSS-----------------SHGQHGSGSSQSSGYGRQGSGSGQ--SPGHGQRGSGS 1605
Query: 461 TQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLD 520
Q P+ +H S + + S +S G S Q S S
Sbjct: 1606 RQS---PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 1662
Query: 521 GGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREE 580
G S Q R + S SS + G+ GS + G + SP+
Sbjct: 1663 YGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS----GSRQSSGHGRQGSGSGQSPSRGRH 1718
Query: 581 ATSPGAKDMPLSSDGNPKVNEKTVGVIVSRE---AMTGRVEKPGGQDKG-SQEDDPAATQ 636
+ G G+ + G SR ++ G+ E G SQ +
Sbjct: 1719 GSGLGHSSSH-GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHF 1777
Query: 637 RPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHN-----GEGNGQS---GHSAA 688
G+ ++ Q G S ++G +S + G G+GQS G +
Sbjct: 1778 CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGS 1837
Query: 689 GPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ-EKGDFTGHGERKGRN- 746
G G +S S GS S GS ++ SGF + + + +T HG G +
Sbjct: 1838 GSGHSSSYGQHGS-GSGWSSSSGRHGSGSGQS-SGFGHHESSSWQSSGYTQHGSGSGHSS 1895
Query: 747 --EKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLL 804
E+ S + +G H S S +H + G + Q+ SRG
Sbjct: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS-PSRGRH 1954
Query: 805 NKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERR 864
G +G SSS P + + + QSS + GS S
Sbjct: 1955 GSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSS-GLGHRESRSGQSSGYGQHGSSSGHS 2013
Query: 865 SVICDISPLRQIVRDPGAH--SLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLK 922
S G H S G S+ + G + + G S ++
Sbjct: 2014 STHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ-----GSGSGQSPGH 2068
Query: 923 SQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSI-------KHESYRGNASP----GAAT 971
Q G + + S + + S H P + HES G +S G+ +
Sbjct: 2069 GQRGSGSRQSPSYGR-HGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGS 2127
Query: 972 HDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPH 1031
S S YG SR R G R G S S+Y + S G R G H
Sbjct: 2128 GHS-SGYGQHGSRSGQSSR-----GERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGH 2181
Query: 1032 ------------HMNPHMTFSERANRSSLHTPF-SPNSETLASAYHANTRAHA-----YG 1073
H + H + RSS P+ S + + H + H+ +G
Sbjct: 2182 SPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG 2241
Query: 1074 DPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVR 1133
+ SQ + Q + + S+G + + QH + S QQ +
Sbjct: 2242 SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS---SHGQHGSGSSQSSSYGQQGSGSGQ 2298
Query: 1134 SPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSR 1193
SP + +G G +G SS G G G + S W S
Sbjct: 2299 SPSRG-----RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 2353
Query: 1194 QTSPAKSSGPPGMSSQ--KRYGPPHETDGHGLAEATQSS--KPGSVMLRLPGQEDH---S 1246
T SG Q R G + HG + + SS + GS + G H S
Sbjct: 2354 YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 2413
Query: 1247 SQNPLIMRRR 1256
Q+P R R
Sbjct: 2414 GQSPSPSRGR 2423
Score = 66.2 bits (160), Expect = 3e-10
Identities = 283/1321 (21%), Positives = 410/1321 (31%), Gaps = 175/1321 (13%)
Query: 3 SFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGA 62
+F ++ S G SY GSS+ + A Q+ SGS S S G
Sbjct: 1322 TFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSG 1381
Query: 63 AAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQ 122
+ +++ SG GF + +G T S + +G
Sbjct: 1382 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG-------CTQHGSGSGHSSSYEQHGSRS 1434
Query: 123 G-SSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQ 181
G SS G ++GS QH G Q G GS Q + + Q
Sbjct: 1435 GQSSRGERHGSSSGSSSSYGQH----GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ 1490
Query: 182 QLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASS 241
Y S + G S SSH + + ++GY GQH SS S
Sbjct: 1491 SSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGY-------GQHGSSSGHS 1543
Query: 242 SSSSSFPSPQRFSQSGQSYD-GSYNVNAG--SQYEGHNVGSN-AQAYGTQSNYSYQPQSM 297
S+ Q S SGQS G + ++G S + H GS+ + YG Q + S Q
Sbjct: 1544 STHG-----QHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG- 1597
Query: 298 KNFEQAKIPQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQVGQ-- 346
G + +Q P +H S QH ++ +S GQ
Sbjct: 1598 ---------HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1648
Query: 347 -YNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPM 405
Y+Q + Q+ S S S S S SS+ +G G G
Sbjct: 1649 SYSQHGSGSGHSSGYGQHGSR-SGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGS 1707
Query: 406 GSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVAN 465
GS P S + +SH G G + G SS+ +
Sbjct: 1708 GSGQ-----SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSG 1762
Query: 466 LPNTV-QHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCS 524
+ QH S Q + S D +S G S Q S ++S G
Sbjct: 1763 HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ 1822
Query: 525 SSSEDQG-ERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGA----------------QNE 567
S Q R R SG SS G S + SS G+ Q+
Sbjct: 1823 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
Query: 568 PPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGS 627
+ S + + SS G + + R GQ
Sbjct: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
Query: 628 QEDDPAATQRPPSNGGAKETSH---------ASLPQPEPPGGGGSKGNKNGDNNSNHN-- 676
P+ ++ +G + +S+ +S P G G S G + ++ S +
Sbjct: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
Query: 677 -GEGNGQSGHSAAGPGFTSRTEPSKSPG-----SLRYSYKDSFGSAVPRNVSGFPQYPTG 730
G+ SGHS+ S + S S G S + S GS ++ SG+ + +G
Sbjct: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQS-SGYGRQGSG 2061
Query: 731 QEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMA-----GSLEGT 785
G GHG+R + + PS G H R S S Q G+ G E +
Sbjct: 2062 --SGQSPGHGQRGSGSRQSPS------YGRHGSGSGRSSSSGQHGPGLGESSGFGHHESS 2113
Query: 786 TRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKF 845
+ + SQ + GS G SS ++ Q
Sbjct: 2114 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHG---------- 2163
Query: 846 EIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLS 905
QSS H GS S SP R HS H + GR+ P S
Sbjct: 2164 SGSRQSSGHGRQGSGSGH-------SPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYES 2216
Query: 906 QSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNA 965
+S G S+ + +S SG S S + SG C + G+
Sbjct: 2217 RS-----GHSSVFGQHESGSGH---------SSAYSQHGSGSGHFC------SQGQHGST 2256
Query: 966 SPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRG 1025
S ++T D Q S G+ G S Y SP R R
Sbjct: 2257 SGQSSTFDQEGSSTGQSSS-----------HGQHGSGSSQSSSYGQQGSGSGQSPSRGRH 2305
Query: 1026 PGGDPHHMN--PHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQL 1083
G H + H + S ++ S H S S ++ ++ Y +G
Sbjct: 2306 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 2365
Query: 1084 HYKR---QMYQQQPEEYKDWSSGSA-------QGVIAAAQHRQEGPRKSPRQQQFLDRVR 1133
Y++ + Q E SSGS+ G + H Q G R
Sbjct: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425
Query: 1134 SPLKNDKDGMMYG------PPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQES 1187
S YG G Y S +G S + G +HGS S
Sbjct: 2426 SGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG-QHGSSSGHSS 2484
Query: 1188 CWDLSRQTSPAKSS-GPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHS 1246
TS SS G G SS + H G G ++++ + GS + PG
Sbjct: 2485 THGQHGSTSGQSSSCGQHGASSGQ--SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 2542
Query: 1247 S 1247
S
Sbjct: 2543 S 2543
Score = 63.2 bits (152), Expect = 2e-09
Identities = 200/926 (21%), Positives = 307/926 (33%), Gaps = 160/926 (17%)
Query: 7 QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGR------- 59
QSS +G Q S + R S + Q+ G+G SS S GSG G+
Sbjct: 1815 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1874
Query: 60 ----------------------------------RGAAAAAAAMASETSGHQGYQGFRKE 85
RG +++ +S + G G G R+
Sbjct: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHG-SGSRQS 1933
Query: 86 AGDFYYMAGNKDPVTTGTPQPPQRR---PSGPVQSYGP-PQGSSFGNQYG----SEGHVG 137
G + +G+ +P P + R SG SYGP GS + + G GH
Sbjct: 1934 LGHGQHGSGSGQ-----SPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSS 1988
Query: 138 QFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQA 197
+ S G S Y Q G S S+ + Q S+ Q Q QS +
Sbjct: 1989 GLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSASGQSSSCGQHGASSGQS-----SS 2041
Query: 198 TGQPASSSSHLQPMQRPSTLPSSAAGYQLRVG------QFGQHYQSSASSSSSSSF-PSP 250
GQ S SS R + + G+ R +G+H S SSSS P
Sbjct: 2042 HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGL 2101
Query: 251 QRFSQSGQSYDGSYNVNAGSQY---EGHNVG-----------SNAQAYGTQSNYSYQPQS 296
S G S ++ SQ+ GH+ G S + +G+ S S +
Sbjct: 2102 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ 2161
Query: 297 MKNFEQAKIPQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQVGQ- 346
+ + G Q P + +H S QH ++++ P +S+ G
Sbjct: 2162 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS 2221
Query: 347 --YNQPEVPVRSPMQFHQNFSP----ISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ 400
+ Q E + Q+ S S ++ QS + S Q+ + Q G
Sbjct: 2222 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS 2281
Query: 401 GSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGF----KGFGLEGVPEKRLTDPGLSS- 455
GS S + Q SP+ S + H++ + G G + + G SS
Sbjct: 2282 GSSQSSSYGQQGSGSGQ-SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG 2340
Query: 456 LSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPM 515
+ QH S + ++ R S + + +S GSS Q S
Sbjct: 2341 FGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGS 2400
Query: 516 AESLDGGCSSSSEDQG---ERVRQLSGQSTSSD-TTYKGGASEKAGSSPAQGAQNEPPRL 571
+SL G S Q R R SG SS + Y G+ + P + L
Sbjct: 2401 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL 2460
Query: 572 NASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDD 631
+ +++ G SS G+ + GQ +
Sbjct: 2461 GHRESRSGQSSGYGQHG---SSSGHSSTH---------------------GQHGSTSGQS 2496
Query: 632 PAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQS-GHSAAGP 690
+ Q S+G + +SH G G S+ + G G G+GQS GH G
Sbjct: 2497 SSCGQHGASSG--QSSSHGQ------HGSGSSQSSGYG-----RQGSGSGQSPGHGQRGS 2543
Query: 691 GFTSRTEPS---KSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ-EKGDFTGHGERKGRN 746
G SR PS GS R S GS + + SGF + + + ++ HG G +
Sbjct: 2544 G--SRQSPSYGRHGSGSGRSSSSGQHGSGLGES-SGFGHHESSSGQSSSYSQHGSGSGHS 2600
Query: 747 EKF---PSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGL 803
+ S + +G H S +H + G R S + + SRG
Sbjct: 2601 SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG---SGSGQSPSRGR 2657
Query: 804 LNKSIGSLLENPHWGPWERKSSSTAP 829
+G + G +SSS P
Sbjct: 2658 HGSGLGHSSSHGQHGSGSGRSSSRGP 2683
Score = 57.8 bits (138), Expect = 1e-07
Identities = 242/1188 (20%), Positives = 379/1188 (31%), Gaps = 165/1188 (13%)
Query: 134 GHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQP 193
G + Q S G + +G GS Q Q Q + S
Sbjct: 167 GQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSG 226
Query: 194 LPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQ------HYQSSASSSSSSSF 247
Q SSS + + ++GY + GQ H SS SSSS
Sbjct: 227 QSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQH 286
Query: 248 PSPQRFS-----QSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQ 302
S R S Q S +V GS G S+ +G+ S+YSY S ++E
Sbjct: 287 GSGSRQSLGHGRQGSGSRQSPSHVRHGS---GSGHSSSHGQHGSGSSYSY---SRGHYES 340
Query: 303 AKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQ 362
Q + GQ + Q S+H +++++ GQ+ S Q
Sbjct: 341 GS-GQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQ-------GQHGSTSGQASSSGQHGS 392
Query: 363 NFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTP 422
+ S S + +S S S+ +G G G GS
Sbjct: 393 S----SRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGS--------------- 433
Query: 423 SMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSS-LSALSTQVANLPNTVQHMLLSDALTP 481
PS H GFG ++ G SS + + QH S +
Sbjct: 434 GQSPSSGQHGT---GFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSG 490
Query: 482 QKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLD---GGCSSSSEDQGERVRQLS 538
+ R S + + +S GSS Q S +SL G S R R S
Sbjct: 491 HGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHES 550
Query: 539 GQSTSSD---TTYKGGASE-----KAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMP 590
G SS Y G S ++GS + G ++ R S + +S G
Sbjct: 551 GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTH 610
Query: 591 LSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQ-----RPPSNG-GA 644
G+ + G A +G+ G GS + Q + PS G
Sbjct: 611 -GQHGSTSGQSSSCG---QHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHG 666
Query: 645 KETSHASLPQPEPPGGG-----GSKGNKNGDNNSNHNGEGNGQ-SGHSAAGPGFTSRTEP 698
+ H+S G G G G+ +G ++ + G+GQ SG+S G G +S +
Sbjct: 667 SDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSG-SSHSSG 725
Query: 699 SKSPGSL--RYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEV 756
+ GS + S + GS+ + S + Q+ +G + +GHG + + PS ++
Sbjct: 726 YRKHGSRSGQSSRSEQHGSSSGLS-SSYGQHGSGSHQS--SGHGRQGSGSGHSPSRVRHG 782
Query: 757 LQGYH------HHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGS 810
H H S S ++ +G G + Q + G + S
Sbjct: 783 SSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQ--GYSQHGSASGHFSS 840
Query: 811 LLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDI 870
+ H + SSS + + Y + +S++H G
Sbjct: 841 --QGRHGSTSGQSSSSGQHDSSSGQSSSYG-------QHESASHHASG------------ 879
Query: 871 SPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKE 930
R S GH + G++ S S G S + S SGQ
Sbjct: 880 ---RGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGS-----GRSSSSGRHGSGSGQSSG 931
Query: 931 EDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATH----DSLSDYGPQDS--- 983
+ S Q+S + H S + R S + H S S YG S
Sbjct: 932 FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSR 991
Query: 984 --------------RPTPMRRVPGRVGGREGMRG--RSPSQYHDFAEKLKMSPGRSRGPG 1027
P+P R G G+ G RS S + + G S G G
Sbjct: 992 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLG 1051
Query: 1028 ------GDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNS 1081
G H + S ++ H S S + ++ ++ ++G +G +
Sbjct: 1052 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 1111
Query: 1082 QLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKD 1141
Y RQ GS G R G R+SP + + +
Sbjct: 1112 SSGYGRQ--------------GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 1157
Query: 1142 GMMYGPPVG-TYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1200
G G G +H+ S+ ++ G + +HGS+ Q S + +S + S
Sbjct: 1158 GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 1217
Query: 1201 S-GPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSS 1247
G G S++ G H G G + + GS + H S
Sbjct: 1218 HYGQHGSGSRQSSG--HGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGS 1263
Score = 46.6 bits (109), Expect = 2e-04
Identities = 77/326 (23%), Positives = 107/326 (32%), Gaps = 39/326 (11%)
Query: 7 QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSG----------------- 49
QS HG + S ++ R S R + Q+ G G SSG
Sbjct: 2534 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH 2593
Query: 50 --SSGSGSGGGRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPP 107
SG SG G+ G+ + ++ G + G + +G+ Q P
Sbjct: 2594 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSP 2653
Query: 108 QRRPSGPVQSY---------GPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTG 158
R G + G + SS G GH F SG G S Y Q +G
Sbjct: 2654 SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG 2713
Query: 159 PFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLP 218
S Q S+ Q Q QS + +G SS +L
Sbjct: 2714 --SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLS 2771
Query: 219 SSAAGY-QLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNV 277
G + +GQH S SS S Q S SGQ DG GS ++G +
Sbjct: 2772 HGRHGSGSGQSSSYGQHGSGSGQSSGYS-----QHGSGSGQ--DGYSYCKGGSNHDGGSS 2824
Query: 278 GSNAQAY-GTQSNYSYQPQSMKNFEQ 302
GS ++ + S Y Y + F Q
Sbjct: 2825 GSYFLSFPSSTSPYEYVQEQRCYFYQ 2850
Score = 42.0 bits (97), Expect = 0.006
Identities = 70/296 (23%), Positives = 105/296 (35%), Gaps = 28/296 (9%)
Query: 7 QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR---GAA 63
QSS +G Q S + G + S + ++ G+G SS S GSG G G
Sbjct: 2521 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580
Query: 64 AAAAAMASETSGHQGYQGFRKEAGDF-----YYMAGNKDPVTTGTPQPPQRRPSGPVQSY 118
+++ +S S H G G G + ++G+ + SG QS
Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 2640
Query: 119 GPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTG---PFSPGSAQYQQQASSQQ 175
G + S Q S G G SGLG S + Q +G S G + + SS
Sbjct: 2641 GHGRQGSGSGQSPSRGRHG------SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVF 2694
Query: 176 QQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHY 235
Q + Y H +G S H + ST + GQ +
Sbjct: 2695 GQHESGSGHSSAYSQH---GSGSGHFCSQGQHGSTSGQSSTFDQEGSS----TGQSSSYG 2747
Query: 236 QSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYS 291
+ SS SS + + + SGQS S+ + + + G + G S YS
Sbjct: 2748 HRGSGSSQSSGY--GRHGAGSGQSL--SHGRHGSGSGQSSSYGQHGSGSGQSSGYS 2799
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 86.3 bits (212), Expect = 3e-16
Identities = 274/1284 (21%), Positives = 412/1284 (32%), Gaps = 223/1284 (17%)
Query: 6 EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAA 65
+ +SY+ N+ +YP + SPR GG+ GS + + G + +++
Sbjct: 211 QYNSYYPNRSAYPPPAPAYALS---SPR-----------GGTPGSGAAAAAGSKPPPSSS 256
Query: 66 AAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQ--RRPSGPVQSYGPPQG 123
A+A +S +S Q Q F G AG P T TP Q PS G P G
Sbjct: 257 ASASSSSSSFAQ--QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGG 314
Query: 124 S-SFGNQYGSEGH------------VGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQ 170
S G Q G G A + GG Q+ + P SPGS+ Q
Sbjct: 315 DYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQ--QRSHHAPMSPGSSGGGGQ 372
Query: 171 ASSQQQQ-----QQVQQLRQQLYQSHQPLPQATGQPAS-SSSHLQP-----MQRPSTLPS 219
++ Q Q+ ++R Q Y P Q G P+ H P Q P P
Sbjct: 373 PLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPM 432
Query: 220 SAAG----------YQLRVGQFGQHYQSSASSSSSSSF-----PSPQRFSQSGQSYDGSY 264
+ G Y ++ +GQ S + + P PQ+ S
Sbjct: 433 TMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQ 492
Query: 265 NVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHP 324
+A Y+ Q +Q YS QP S +Q+ P +QQ QQ PQ Q
Sbjct: 493 TPHAQPSYQQQPQSQPPQLQSSQPPYSQQP-SQPPHQQSPAPYPSQQSTTQQHPQSQPPY 551
Query: 325 SQHVMQ--YTNAATKLPLQSQVGQ---YNQPEVPVRSPMQFHQNFSP----ISNPSPAAS 375
SQ Q Y + P S + Q Y QP+ + Q P +S S +
Sbjct: 552 SQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQ 611
Query: 376 VVQSPSCSSTPSPLMQTGENLQCGQGSVP-MGSRNRILQLMPQLSPTPSMMPSPNSHAAG 434
+PS +S+ +LQ S+P + L + + + +P + S S + G
Sbjct: 612 ASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQG 671
Query: 435 FKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHML---LSDALTPQKKTSKRPSS 491
+ + P T P L + S P +V LS A P + RP S
Sbjct: 672 EQSNPAQS-PFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPS 730
Query: 492 ---------SKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSG--- 539
S S G Q Q+ + G S + G ++ G
Sbjct: 731 GQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ-YSSPQPGSALSPRQPSGGQIHTGMGSYQ 789
Query: 540 QSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP-GAKDMPLSSDGNPK 598
Q++ +GG G P Q N P N A +P GA G P
Sbjct: 790 QNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPP 849
Query: 599 VNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLP----- 653
G R + +P G + + + PP G ++T ++
Sbjct: 850 YGTLPPG----RMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAA 905
Query: 654 ---QPEPPG-----GGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSL 705
Q PPG GG G G GQ +S AG + P G++
Sbjct: 906 NSIQNRPPGYPNMNQGGMMG----------TGPPYGQGINSMAGM-INPQGPPYSMGGTM 954
Query: 706 RYSYKDSFGSAVPRNVSGFPQYPTG-----QEKGDFTGHGERKGRNEKFPSLLQEVLQGY 760
+S G A + G K D T E K + + E +
Sbjct: 955 A---NNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKL 1011
Query: 761 HH---HPDR-----RYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGSLL 812
+ P+R RY T+E G T + + +L + K IG L
Sbjct: 1012 YELGGEPERKMWVDRYLAFTEE------KAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLT 1065
Query: 813 ENPHWGPWER--------KSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERR 864
+ W SSS A +K+ + FE + + P +
Sbjct: 1066 QVNKNKKWRELATNLNVGTSSSAASSLKKQYI---QCLYAFECKIERGEDPPPDIFA--- 1119
Query: 865 SVICDISPLRQIVRDPGAHSLGHM-------SADTRIGRNDRLNPTL------SQSVILP 911
D + ++ P G M S + + L P SQ LP
Sbjct: 1120 --AADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLP 1177
Query: 912 GGLVSMETKLKSQSGQIKEEDFEQSKSQASF--NNKKSGDHCHPPSIKHESYRGNASPGA 969
G S+S + +D S ++F N + + + PS+ G S
Sbjct: 1178 G---------MSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMS--- 1225
Query: 970 ATHDSLSDYGPQDSRPTPMRRVPGR---VGGREGMRGRSPSQYHDFAEKLKMSPGRSRGP 1026
Y P MR+ PG + +G G Y R+ GP
Sbjct: 1226 --------YEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY-----------SRAAGP 1266
Query: 1027 GGDPHHMNP--HMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLH 1084
G M P H + +R P A N +P++G+ S
Sbjct: 1267 GLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMP---SNPDSGMYSPSR 1323
Query: 1085 YKRQMYQQQPEEYKDWSSG-SAQGVIAAAQHRQEGPRKSPRQQQF---------LDRVRS 1134
Y Q QQQ + + + + S QG + + + +QQQ ++ S
Sbjct: 1324 YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTS 1383
Query: 1135 PLKND--KDGMMY---GPPVGTYH 1153
P K+ GM GPPV H
Sbjct: 1384 PSKSPFLHSGMKMQKAGPPVPASH 1407
Score = 50.8 bits (120), Expect = 1e-05
Identities = 163/799 (20%), Positives = 263/799 (32%), Gaps = 95/799 (11%)
Query: 39 QNFGGTGGSSGSSGSGSGGG---------RRGAAAAAAAMASETSGHQGYQGFRKEAG-- 87
Q+ + G G G+GSGGG G A A+ + + G G G
Sbjct: 74 QDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133
Query: 88 -DFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGL 146
+ A P G QP R PS + + F Q+G + G Q G
Sbjct: 134 APPHSAAAALPPPAYGFGQPYGRSPS----AVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189
Query: 147 GGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSS 206
GG+ Y G +Q + + S + +G A++ S
Sbjct: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGS 249
Query: 207 HLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQ-----RFSQSGQSYD 261
P S SS++ Q R G G S+A + +P S + Y
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309
Query: 262 G--SYNVNAGSQYEGHNVG---SNAQAYGTQSNYSYQPQSMKNFEQ----AKIPQGTQQG 312
G + + G Q G G +Q +G + + + +Q A + G+ G
Sbjct: 310 GYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG 369
Query: 313 QQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVG--QYNQPEVPVRSPMQFH--------- 361
Q + Q PS + Q K+ Q G Y+Q + P P Q H
Sbjct: 370 GGQPLARTPQ-PSSPMDQ----MGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGS 424
Query: 362 ---QNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRN--RILQLMP 416
Q + P++ A S + S + P Q G + QG P ++ Q P
Sbjct: 425 QTPQRY-PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQP 483
Query: 417 QLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHML-- 474
S P PS HA + P+ + P L S +Q + P Q
Sbjct: 484 PYSQQP---PSQTPHAQP----SYQQQPQSQ--PPQLQSSQPPYSQQPSQPPHQQSPAPY 534
Query: 475 -LSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGER 533
+ T Q S+ P S +A S + QP S A S + +
Sbjct: 535 PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQ 594
Query: 534 VRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSS 593
R Q S D+ +S + +S G ++ L + P++ + S D+P+ +
Sbjct: 595 QRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPD-LSGSIDDLPMGT 653
Query: 594 DGNPKVNEKTVGVIVSREAMTGRVEKPGGQD-----KGSQEDDPAATQRPPSNGGAKE-- 646
+G T G+ S+ + + P G + P+ P S ++
Sbjct: 654 EGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGP 713
Query: 647 TSHASLP---QPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPG 703
S A++P P P G S + N + + G + P ++ S PG
Sbjct: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYS-----SPQPG 768
Query: 704 SLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHH 763
S S + G + + + Q G + G + G +P Y+
Sbjct: 769 S-ALSPRQPSGGQIHTGMGSYQQ----NSMGSYGPQGGQYGPQGGYPR-----QPNYNAL 818
Query: 764 PDRRYSRSTQEHQGMAGSL 782
P+ Y + GMAG +
Sbjct: 819 PNANYPSA-----GMAGGI 832
Score = 32.3 bits (72), Expect = 4.6
Identities = 66/292 (22%), Positives = 100/292 (34%), Gaps = 54/292 (18%)
Query: 1357 QKITSPNIRRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKR------KG 1410
Q +TSP+ SA GGD SG P+ G AD+ +
Sbjct: 297 QLLTSPS---SARGYQGYPGGDY----------SGGPQDGGAGKGPADMASQCWGAAAAA 343
Query: 1411 EVASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQ 1470
A+ A Q H P SS + + + + + + P T+ SQ
Sbjct: 344 AAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ 403
Query: 1471 KPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVT--ISPKQEGF 1528
+ QG P G G +P P G P+ P + + +S Q+
Sbjct: 404 Q----QGPPSGPQQGHG---YPGQ----PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQ-I 451
Query: 1529 PPKGYF-PSGKKKGRPIGSVNKQK---KQQQPPPPPPQPPQIPEGSADGEPKPKKQ---- 1580
PP G PSG + N+Q +QQQPP P Q P + +P+ Q
Sbjct: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511
Query: 1581 -----------RQRRERRKPGAQPRKRKTKQAVPIVEP--QEPEIKLKYATQ 1619
Q ++ P P ++ T Q P +P +P+ + Y Q
Sbjct: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQ 563
Score = 32.3 bits (72), Expect = 4.6
Identities = 37/156 (23%), Positives = 59/156 (37%), Gaps = 44/156 (28%)
Query: 1465 TSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPK 1524
+ T + P + QGR ++GG + ++ +PP G
Sbjct: 424 SQTPQRYPMTMQGRAQSAMGGLSY-----TQQIPPYG----------------------- 455
Query: 1525 QEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRR 1584
Q+G P GY G++ P + QQQ PP QPP S +P Q+Q
Sbjct: 456 QQG--PSGY---GQQGQTPYYNQQSPHPQQQQPPYSQQPP-----SQTPHAQPSYQQQ-- 503
Query: 1585 ERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1620
P +QP + ++ Q +P +P + A P
Sbjct: 504 ----PQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP 535
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 84.0 bits (206), Expect = 1e-15
Identities = 258/1319 (19%), Positives = 425/1319 (32%), Gaps = 193/1319 (14%)
Query: 5 REQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGT-GGSSGS--SGSGSGGGRRG 61
R S G Q+S ++ SSR Q + + G + GG GS S G G
Sbjct: 1781 RTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSG 1840
Query: 62 AAAAAAAMASETSGHQGYQGFR---------KEAGDFYYMAGNKDPVTTGTPQPPQRRPS 112
+ + + +G G R K++GD +G++ + +
Sbjct: 1841 SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQV 1900
Query: 113 GPVQSYGPP----QGSSFGNQYGSEGHVGQFQAQHSGLGGVSH----YQQDYTGPFSPGS 164
G QS GP QGSS S+GH + + SG +H ++Q G PGS
Sbjct: 1901 GQGQSSGPRTSRNQGSSVSQDSDSQGH-SEDSERWSGSASRNHLGSAWEQSRDGSRHPGS 1959
Query: 165 AQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGY 224
++ +A +Q + +S + GQ ASS + S+AG
Sbjct: 1960 -HHEDRAGHGHSADSSRQSGTRHTES-----SSRGQAASSHEQAR----------SSAGE 2003
Query: 225 QLRVGQFGQHYQ-SSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQA 283
+ G H+Q SA SS S Q S S Y+ + S EGH+ S+ Q+
Sbjct: 2004 R-----HGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQS 2058
Query: 284 YGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQ----QQQPQQQQHPSQHVMQYTNAATKLP 339
Q QS K E A+ G G+ Q +Q S H + +
Sbjct: 2059 VSAQGKAGPHQQSHK--ESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGR-- 2114
Query: 340 LQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCG 399
Q Y+Q + R + +P P+ Q S + ++G +
Sbjct: 2115 ---QGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQG---SHQEQSVDRSGHS---- 2164
Query: 400 QGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSAL 459
GS + S T S S S +K + G +
Sbjct: 2165 ------GSHH---------SHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSH 2209
Query: 460 STQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESL 519
+ ++ ++ +H L+ + +TS+ SS DS +SEG S+ E+ + +
Sbjct: 2210 HHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDS--DSEGHSEDSERRSGSASRNH 2267
Query: 520 DGGCSSSSEDQGERVRQ----LSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASP 575
G S D R +G S++++ + G SS Q A + + +S
Sbjct: 2268 HGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHE-QARSSA 2326
Query: 576 AAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAAT 635
R + + D S + + V G +G ED +
Sbjct: 2327 GERHGSHHQQSAD----SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQS 2382
Query: 636 QRPPSNGGAKETSHASLPQPEPPGGGGSKGN--------------------KNGDNNSNH 675
G + SH + G G G+ G +H
Sbjct: 2383 VSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSH 2442
Query: 676 NGEGNGQSGHSAAGPGF-TSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKG 734
+ + S HS + G T P S G + S+ + + S + T Q +
Sbjct: 2443 HKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHH-SHTTSQGRS 2501
Query: 735 DFT-GHG-----ERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRP 788
D + GH R+ RN++ HH R S G S T
Sbjct: 2502 DASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSR 2561
Query: 789 NVLVSQTNELASRGLLNKS---IGSLLENPHWGPWER-KSSSTAPEMKQINLTDYPIPRK 844
N S + + S+G S GS N H E+ + S P Q + +
Sbjct: 2562 NWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSAD 2621
Query: 845 FEIEP------------QSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHS-LGHMSAD 891
+ +S+HE S + R Q D HS +GH A
Sbjct: 2622 SSRQSGTRHTQTSSGGQAASSHEQARSSAGERH-----GSHHQQSADSSRHSGIGHGQAS 2676
Query: 892 TRIGRNDRLNPTLSQSVILPGGLVSMETKLKS---QSGQIKEEDFEQSKSQASFNNKKSG 948
+ + + + SQ+ G +T+ S Q+G ++ E ++ ++ + SG
Sbjct: 2677 SAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSG 2736
Query: 949 DHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSP-- 1006
+ S +S + G +T GR G R S
Sbjct: 2737 SFLYQVSTHEQSESSHGWTGPSTR--------------------GRQGSRHEQAQDSSRH 2776
Query: 1007 SQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHAN 1066
S D + ++ PG SRG R H S +S + ++H++
Sbjct: 2777 SASQDGQDTIRGHPGSSRG------------------GRQGYHHEHSVDSSGHSGSHHSH 2818
Query: 1067 TRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIA----------AAQHRQ 1116
T + D + G + R ++ SGS + A Q +
Sbjct: 2819 TTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQS 2878
Query: 1117 EGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGME 1176
EG R+S RQ + + + +D + H SAQE L P E
Sbjct: 2879 EGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQ---LRDGSRHPRSHQE 2935
Query: 1177 LKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSV 1235
+ G +S + + S G S ++ E G ++ SS+ +
Sbjct: 2936 DRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2994
Score = 80.5 bits (197), Expect = 1e-14
Identities = 288/1429 (20%), Positives = 471/1429 (32%), Gaps = 214/1429 (14%)
Query: 6 EQSSYHGNQQSYPQEVHGS--------SRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGG 57
+ +S H +S P E HGS SR QA + G GSSGS S S G
Sbjct: 368 QTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEG 427
Query: 58 GRR--------GAAAAAAAMASETSGHQGYQGFR--KEAGDFYYMAGNKDP--------V 99
G A S +G G R + Y ++ ++ P
Sbjct: 428 HSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGT 487
Query: 100 TTGTPQPPQRRPSGPVQSYGPPQ----------GSSFGNQYGSEGHVGQFQAQHSGLGGV 149
+TG Q + + Q GSS G + GS ++ HSG
Sbjct: 488 STGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSG---- 543
Query: 150 SHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQ 209
SH+ + S S S+ +Q + +Q S +A+ Q A SS H Q
Sbjct: 544 SHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQ-ADSSRHSQ 602
Query: 210 PMQRPSTLPSSAAGYQLRVGQFGQ---HYQSS---ASSSSSSSFPSPQRFSQSGQSYDGS 263
Q S+ P ++ V Q H + S + S+S + S Q S+ G + S
Sbjct: 603 VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRS 662
Query: 264 YNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQ------- 316
++ + GH+ S+ ++ + S Q+ + EQA+ G + G + Q
Sbjct: 663 HHEDRAGH--GHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSS 720
Query: 317 --------QPQQQQHPSQHVMQYTNAATKLPLQSQ------VGQYNQPEVPVRSPMQFHQ 362
Q S H + AT S+ V + Q +S + +
Sbjct: 721 RHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESAR 780
Query: 363 NFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTP 422
+ S + + + Q + + S TG + QGS +R+ Q
Sbjct: 781 DRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQ-DGQD 839
Query: 423 SMMPSPNSHAAGFKG---------FGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHM 473
++ P S G +G G G T G S S + + T ++
Sbjct: 840 TIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN- 898
Query: 474 LLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGER 533
Q + R S S+ ++ ++++ S + + + +G R
Sbjct: 899 ------EEQSRDGSRHSGSRHHEASSHADISRHSQ---------------AGQGQSEGSR 937
Query: 534 VRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSS 593
+ G S S D+ +G + + S G+ + R +A +R + P + +
Sbjct: 938 TSRRQGSSVSQDSDSEGHSED---SERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAG 994
Query: 594 DGNPKVNEKTVGVIVSREAMTGRVE-KPGGQDKGSQE---DDPAATQRPPSNGGAKETSH 649
G+ + SR++ T E GGQ S E P A + H
Sbjct: 995 HGHSADS--------SRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRH 1046
Query: 650 ASLPQPE------PPGGGGSKGNKNGDNNSNHNGEGNGQ--SGHSAAGPGFTSRTEPSKS 701
+ +P+ + G GS G++ D + H+ E + Q SGH GP S E
Sbjct: 1047 SGIPRRQASSAVRDSGHWGSSGSQASD-SEGHSEESDTQSVSGHGQDGPHQQSHQE---- 1101
Query: 702 PGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYH 761
S +D G R+ S Q T ++ + HG + + QG H
Sbjct: 1102 ------SARDWSGGRSGRSGSFIYQVSTHEQSE--SAHGRTRTSTGR--------RQGSH 1145
Query: 762 HHPDRRYSR--STQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGP 819
H R SR ++QE Q + G+ R S + R S H
Sbjct: 1146 HEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDR--------SGHSGSHHSH 1197
Query: 820 WERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRD 879
+ S A + + + RK + S H GS + D S Q+ ++
Sbjct: 1198 TTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRH--SGSRHHEAASWADSSRHSQVGQE 1255
Query: 880 PGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQ 939
+ S + + ++ S L G + ++ G +E+ + S+
Sbjct: 1256 QSSGSRTSRHQGSSVSQDSDSERHSDDSERLSG------SASRNHHGSSREQSRDGSR-H 1308
Query: 940 ASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGRE 999
F+ + H H +S H S +G S R PG G
Sbjct: 1309 PGFHQEDRASHGHSADSSRQS--------GTHHTESSSHGQAVSSHEQARSSPGERHGSR 1360
Query: 1000 GMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETL 1059
+ S++ + S R G G +T SE + S S + +
Sbjct: 1361 HQQSADSSRHSGIGHRQASSAVRDSGHRGS---SGSQVTNSEGHSEDSDTQSVSAHGQAG 1417
Query: 1060 ASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDW--SSGSAQGVIAAAQHRQE 1117
A ++G + Y+ ++Q + S+G QG R E
Sbjct: 1418 PHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQG------SRHE 1471
Query: 1118 GPRKSPR---QQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRC-LMSSDGLPNK 1173
R S R Q D +R G G G+YH+ S +G S P
Sbjct: 1472 QARNSSRHSASQDGQDTIRG-----HPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQG 1526
Query: 1174 GMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPP--------HETDGHGLAE 1225
+ HG Q SRQT + SG S R+ P H G G +
Sbjct: 1527 RSDASHG----QSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESA 1582
Query: 1226 ATQSS-KPGSVMLRLPGQEDHSSQNPLIMRRRVRS-FISPIPSKRQSQDVKNSSTEDKGR 1283
+++S + GS + + E HS + R+ + S R S ED+
Sbjct: 1583 GSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRAS 1642
Query: 1284 LLHSSKEG-------ADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDS 1325
HS++ A+ + A S Q S +R S+ S DS
Sbjct: 1643 HGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADS 1691
Score = 77.4 bits (189), Expect = 1e-13
Identities = 301/1429 (21%), Positives = 487/1429 (34%), Gaps = 225/1429 (15%)
Query: 1 MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 60
+ S + S HG Q+ P E + ++ + G G GS S GGR+
Sbjct: 1445 VSSHEQSESTHG--QTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGS-SRGGRQ 1501
Query: 61 GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 120
G+ + + SGH GY + + + + Q SG +
Sbjct: 1502 GSYHEQSV---DRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSG 1558
Query: 121 PQGSSFGNQYGSEGH--VGQFQAQHSGLG---GVSHYQQDYTGPFSPGSAQYQQQASSQQ 175
+ + GS H VGQ ++ S G S Q + S S + + AS
Sbjct: 1559 SRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNH 1618
Query: 176 QQQQVQQLR--QQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRV----- 228
+Q R + +SHQ + G A SS ++ AA Q +
Sbjct: 1619 YGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPG 1678
Query: 229 GQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAY---- 284
+ G +Q SA SS+ S Q S G S + + + S EGH+ S+ Q+
Sbjct: 1679 ERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHG 1738
Query: 285 ---------------------GTQSNYSYQPQSMKNFEQAKIPQG-TQQGQQQQQPQQQQ 322
G ++ YQ + + E A G + G+Q+ + +Q +
Sbjct: 1739 QAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQAR 1798
Query: 323 HPSQHVMQYTNAAT--KLPLQSQVG-QYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQS 379
S+H T P S+ G Q + E V S H S S V S
Sbjct: 1799 DSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDS--SGHSGSHHSHTTSQERSDV-S 1855
Query: 380 PSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLM------PQLSPTPSMMP--SPNSH 431
S + S QT Q G GS GSR+ Q+ S P S N
Sbjct: 1856 RGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQG 1915
Query: 432 AAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSS 491
++ + +G E G +S + L + + +H P R
Sbjct: 1916 SSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRH--------PGSHHEDRAGH 1967
Query: 492 SKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGG 551
ADS S G+ E + A S + SS+ E G + S S+ G
Sbjct: 1968 GHSADSSRQS-GTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQ 2026
Query: 552 ASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSRE 611
AS S +G + S A+ E S + +S+ G ++++ +E
Sbjct: 2027 ASSAVRDSGHRG-------YSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQS-----HKE 2074
Query: 612 AMTGRVEKPGG-------QDKGSQEDDPAATQRPPSNGG--------AKETSHASLPQPE 656
+ G+ + G Q ++ + Q PS GG A+++S S Q
Sbjct: 2075 SARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEG 2134
Query: 657 PPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTS---RTEPSKSPGSLRYSYKDSF 713
G G G +H + +SGHS + T+ R++ S+ R + + ++
Sbjct: 2135 QDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTY 2194
Query: 714 G---SAVPRNVSGFPQYPTG----QEKGDFTGHGERKGRNEKFP---SLLQEV-LQGYHH 762
S SG + + G G+ G P S+ Q+ +G+
Sbjct: 2195 DKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSE 2254
Query: 763 HPDRRYSRSTQEHQGMA--GSLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPW 820
+RR +++ H G A S +G+ P S + A G + + S H
Sbjct: 2255 DSERRSGSASRNHHGSAQEQSRDGSRHPR---SHHEDRAGHG--HSAESSRQSGTHHA-- 2307
Query: 821 ERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDP 880
E S A + + +SSA E GS ++ + D
Sbjct: 2308 ENSSGGQAASSHE--------------QARSSAGERHGSHHQQSA-------------DS 2340
Query: 881 GAHS-LGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKS---QSGQIKEEDFEQS 936
HS +GH A + + + + SQ+ G +T+ S Q+G ++ E +
Sbjct: 2341 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST 2400
Query: 937 KSQASFNNKKSGDHCHPPSIKHESYRGNASPGAAT-------HDSLSDYGPQDSRPTPMR 989
+ +++ + +SG + S +S + G +T H D +
Sbjct: 2401 RGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQD 2460
Query: 990 RVPGRVGGREGMRGRSPSQYHDFAEKL---------KMSPGRSRGPGGDPHHMNPHMTFS 1040
+ G G G GR S Y ++ S GRS D H + +
Sbjct: 2461 TIHGHPGSSSG--GRQGSHYEQLVDRSGHSGSHHSHTTSQGRS-----DASHGHSGSRSA 2513
Query: 1041 ERANRSSLHTPFSPNSETLASAYH-ANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKD 1099
R R+ + S S +H A++RA + G G Q + P ++
Sbjct: 2514 SRQTRNDEQS--GDGSRHSGSRHHEASSRADSSGHSQVG---------QGQSEGPRTSRN 2562
Query: 1100 WSSGSAQGVIAAAQHRQEGPRKS---------PRQQQFLDRVRSPLKNDKDGMMYGPPV- 1149
W S +Q + H ++ R S Q+Q D R P + +D +G
Sbjct: 2563 WGSSFSQDSDSQG-HSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSAD 2621
Query: 1150 -----GTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQ--------TS 1196
GT H ++ G+ S + + E +HGS Q + D SR +S
Sbjct: 2622 SSRQSGTRHTQTS-SGGQAASSHEQARSSAGE-RHGSHHQQSA--DSSRHSGIGHGQASS 2677
Query: 1197 PAKSSGPPGMS-SQKRYGPPHETD-------GHGLAEATQSSKPGSVMLRLPGQEDHSSQ 1248
+ SG G S SQ H D HG A + Q S S R HS
Sbjct: 2678 AVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGS 2737
Query: 1249 NPLIMRRRVRSFIS---PIPSKRQSQDVKNSSTEDKGRLLHS-SKEGAD 1293
+ +S S PS R Q ++ +D R HS S++G D
Sbjct: 2738 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR--HSASQDGQD 2784
Score = 74.3 bits (181), Expect = 1e-12
Identities = 272/1344 (20%), Positives = 428/1344 (31%), Gaps = 220/1344 (16%)
Query: 8 SSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGS-----GSGGGRRGA 62
SS H Q +HG RQ ++ G SGS S G G
Sbjct: 2449 SSRHSTSQEGQDTIHGHPGSSS-GGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGH 2507
Query: 63 AAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQ 122
+ + +A + Q G R + + D ++G Q Q + GP S
Sbjct: 2508 SGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRAD--SSGHSQVGQGQSEGPRTSRN--W 2563
Query: 123 GSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQ 182
GSSF S+GH + + SG +H+ GSAQ Q + S+ +
Sbjct: 2564 GSSFSQDSDSQGH-SEDSERWSGSASRNHH----------GSAQEQLRDGSRHPR----- 2607
Query: 183 LRQQLYQSHQPLPQATGQPASSS--SHLQPMQRPSTLPSSAAGYQLRVG---QFGQHYQS 237
SHQ G A SS S + Q S ++++ Q R + G H+Q
Sbjct: 2608 -------SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ 2660
Query: 238 SASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS- 296
SA SS S Q S S Y+ + S EGH+ S+ Q+ QS
Sbjct: 2661 SADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSH 2720
Query: 297 ---------------------MKNFEQAKIPQG----TQQGQQQQQPQQQQHPSQHVMQY 331
+ EQ++ G + +G+Q + +Q Q S+H
Sbjct: 2721 QESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQ 2780
Query: 332 TNAATKL--PLQSQVGQ---YNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTP 386
T P S+ G+ +++ V H + + S A S S +
Sbjct: 2781 DGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDA-----SRGQSGSR 2835
Query: 387 SPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEK 446
S T Q G GS GSR+ +S + + + + G +
Sbjct: 2836 SASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDS 2895
Query: 447 RLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQ 506
S + N + Q L + P+ R ADS S G+
Sbjct: 2896 DSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQS-GTRH 2954
Query: 507 PEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQN 566
+ A S + SS+ E G +Q + S S + G AS S +G
Sbjct: 2955 TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH-GQASSAVRDSGHRG--- 3010
Query: 567 EPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGG---- 622
+ S A+ E S + +S+ G ++++ +E+ GR + G
Sbjct: 3011 ----YSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQS-----HQESARGRSGETSGHSGS 3061
Query: 623 ---QDKGSQEDDPAATQRPPSNGG--------AKETSHASLPQPEPPGGGGSKGNKNGDN 671
Q ++ + + PS G A+++S S Q G G+ G
Sbjct: 3062 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGR 3121
Query: 672 NSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ 731
H+ SGHS + T T +S S S S S RN +
Sbjct: 3122 QGYHHEHSVDSSGHSGSHHSHT--TSQGRSDASRGQSGSRS-ASRTTRNE---------E 3169
Query: 732 EKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVL 791
+ GD + H + HH ++ ++ Q + G EG+ R
Sbjct: 3170 QSGDSSRHSVSR------------------HHEASTHADISRHSQAVQGQSEGSRRSRRQ 3211
Query: 792 VSQTNELASRGLLNKSIGSLLENPHW-GPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQ 850
S ++ + S G ++ W G R + E + PR +
Sbjct: 3212 GSSVSQDSD------SEGHSEDSERWSGSASRNHRGSVQEQSRHGSRH---PRSHHEDRA 3262
Query: 851 SSAHEPGGSLSERRSVICDISPLRQIVRDPG-----AHSLGHMSADTRIGRNDRLNPTLS 905
H S S R G +H S R G + + S
Sbjct: 3263 GHGHSADRSRQ---------SGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSS 3313
Query: 906 QSVILPGGLVSMETKLKSQSGQI------KEEDFEQSKSQASFNNKKSGDH--CHPPSIK 957
+ +P G S + G E E+S +Q+ + ++G H H S +
Sbjct: 3314 RHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESAR 3373
Query: 958 HESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLK 1017
S + G+ + +S + +S R GR G + R S++ E
Sbjct: 3374 DRSGGRSGRSGSFLYQ-VSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQD 3432
Query: 1018 MSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNA 1077
G PG S R R H S + + ++H++T + D +
Sbjct: 3433 TIRGH---PG------------SSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASR 3477
Query: 1078 GLNSQLHYKRQMYQQQPE---EYKDWSSGSAQGVIA-------AAQHRQEGPRKSPRQQQ 1127
G + RQ + WS A + Q + GPR S Q
Sbjct: 3478 GQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGS 3537
Query: 1128 FLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQES 1187
+ + + +D + H SAQE R P E + G ES
Sbjct: 3538 SVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSR---DGSRHPTSHHEDRAGHGHSAES 3594
Query: 1188 CWDLSRQTS---PAKSSGPPGMSSQ--------KRYGPPHETD---------GHGLAEAT 1227
SRQ+ SSG SS +R+G H+ GHG A +
Sbjct: 3595 ----SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSA 3650
Query: 1228 --QSSKPGSVMLRLPGQEDHSSQN 1249
S GS + E HS +
Sbjct: 3651 VRDSGHRGSSGSQASDSEGHSEDS 3674
Score = 73.2 bits (178), Expect = 2e-12
Identities = 251/1298 (19%), Positives = 415/1298 (31%), Gaps = 170/1298 (13%)
Query: 6 EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAA 65
+ SS H Q + G + + Q+ +G S + GR A+
Sbjct: 2123 QDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRG 2182
Query: 66 AAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP----P 121
+ S ++ + Y ++++GD +G+ + + G QS GP P
Sbjct: 2183 QSG--SRSASRKTYD--KEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRP 2238
Query: 122 QGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQ 181
+GSS SEGH + + SG +H+ GSAQ Q + S+ + +
Sbjct: 2239 RGSSVSQDSDSEGH-SEDSERRSGSASRNHH----------GSAQEQSRDGSRHPRSHHE 2287
Query: 182 QLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASS 241
R S + Q+ A +SS Q SSA + G H+Q SA S
Sbjct: 2288 D-RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGE------RHGSHHQQSADS 2340
Query: 242 SSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAY----------------- 284
S S Q S S + + S EGH+ S+ Q+
Sbjct: 2341 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST 2400
Query: 285 --------GTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPS------QHVMQ 330
G ++ YQ + + E A GT G +Q +Q S Q
Sbjct: 2401 RGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQD 2460
Query: 331 YTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLM 390
+ + G + + V H + + S A S S + S
Sbjct: 2461 TIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDA-----SHGHSGSRSASR 2515
Query: 391 QTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTD 450
QT + Q G GS GSR+ S + + + +G +
Sbjct: 2516 QTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQG 2575
Query: 451 PGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQ 510
S + N + Q L + P+ R ADS S G+ +
Sbjct: 2576 HSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQS-GTRHTQTS 2634
Query: 511 LKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPR 570
A S + SS+ E G +Q + S S + G AS S +G
Sbjct: 2635 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH-GQASSAVRDSGHRG------- 2686
Query: 571 LNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGG-------Q 623
+ S A+ E S + +S+ G ++++ +E+ GR + G Q
Sbjct: 2687 YSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQS-----HQESARGRSGETSGHSGSFLYQ 2741
Query: 624 DKGSQEDDPAATQRPPSNGG--------AKETSHASLPQPEPPGGGGSKGNKNGDNNSNH 675
++ + + PS G A+++S S Q G G+ G H
Sbjct: 2742 VSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYH 2801
Query: 676 NGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGD 735
+ SGHS + T T +S S S S S RN ++ GD
Sbjct: 2802 HEHSVDSSGHSGSHHSHT--TSQGRSDASRGQSGSRS-ASRTTRNE---------EQSGD 2849
Query: 736 FTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQT 795
+ H G HH ++ ++ Q + G EG+ R S
Sbjct: 2850 GSRHS------------------GSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSV 2891
Query: 796 NELASRGLLNKSIGSLLENPHW-GPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAH 854
++ + S G ++ W G R +A E + PR + + H
Sbjct: 2892 SQDSD------SEGHSEDSERWSGSASRNHHGSAQEQLRDGSRH---PRSHQEDRAGHGH 2942
Query: 855 EPGGSLSERRSVICDISPLRQIVRDPG-----AHSLGHMSADTRIGRNDRLNPTLSQSVI 909
S S R G +H SA R G + + + S+
Sbjct: 2943 SADSSRQ---------SGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG 2993
Query: 910 LPGGLVSMETKLKSQSGQI------KEEDFEQSKSQASFNNKKSGDH--CHPPSIKHESY 961
+ G S + G E E S +Q+ + ++G H H S + S
Sbjct: 2994 IGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSG 3053
Query: 962 RGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGR----EGMRGRSPSQYHDFAEKLK 1017
+ G+ + + + S GR G R + S SQY + ++
Sbjct: 3054 ETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQ--DTIR 3111
Query: 1018 MSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNA 1077
PG SRG HH + + + S H+ + + AS + +R+ + N
Sbjct: 3112 GHPGSSRGGRQGYHHEH---SVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNE 3168
Query: 1078 GLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLK 1137
+ + + D S S A Q + EG R+S RQ + +
Sbjct: 3169 EQSGDSSRHSVSRHHEASTHADISRHSQ-----AVQGQSEGSRRSRRQGSSVSQDSDSEG 3223
Query: 1138 NDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSP 1197
+ +D + H S QE R P E + G + + +
Sbjct: 3224 HSEDSERWSGSASRNHRGSVQEQSR---HGSRHPRSHHEDRAGHGHSADRSRQSGTRHAE 3280
Query: 1198 AKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSV 1235
S G S ++ P E G ++ SS+ +
Sbjct: 3281 TSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGI 3318
Score = 67.8 bits (164), Expect = 1e-10
Identities = 261/1254 (20%), Positives = 425/1254 (33%), Gaps = 195/1254 (15%)
Query: 3 SFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGA 62
S ++S H + + Q V G S S RQ + G S S SG R
Sbjct: 2856 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 2915
Query: 63 AAAAAAMASETSGH-QGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPP 121
+A + S H + +Q R AG + ++ T T Q G S
Sbjct: 2916 HGSAQEQLRDGSRHPRSHQEDR--AGHGHSADSSRQSGTRHT----QTSSGGQAASSHEQ 2969
Query: 122 QGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQ----------QDYTGPFSPGSAQYQQQA 171
SS G ++GS ++HSG+G H Q + Y+G + + + + +
Sbjct: 2970 ARSSAGERHGSHHQQSADSSRHSGIG---HGQASSAVRDSGHRGYSGSQASDNEGHSEDS 3026
Query: 172 SSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQP-MQRPSTLPSSAA-----GYQ 225
+Q Q Q QSHQ A G+ +S H + + ST S + G
Sbjct: 3027 DTQSVSAHGQAGSHQ--QSHQ--ESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS 3082
Query: 226 LRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYG 285
R Q +H Q+ SS S+S Q + + + GS + H+V S+ +
Sbjct: 3083 TRGRQGSRHEQAQDSSRHSAS----QYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGS 3138
Query: 286 TQSNYSYQPQSMKNFEQ--AKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQ 343
S+ + Q +S + Q ++ T + ++Q + S+H T+A Q+
Sbjct: 3139 HHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAV 3198
Query: 344 VGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQ-SPSCSSTPSPLMQTGENLQCGQGS 402
G Q E RS Q +SV Q S S + +G + +GS
Sbjct: 3199 QG---QSEGSRRSRRQ-------------GSSVSQDSDSEGHSEDSERWSGSASRNHRGS 3242
Query: 403 VPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQ 462
V SR+ P SH G G R + + S+ Q
Sbjct: 3243 VQEQSRHG--------------SRHPRSHHEDRAGHG-HSADRSRQSGTRHAETSS-GGQ 3286
Query: 463 VANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGG 522
A+ + +P ++ R S ADS S S P Q S + +S G
Sbjct: 3287 AASSHEQARS-------SPGERHGSRHQQS--ADS---SRHSGIPRGQASSAVRDSRHWG 3334
Query: 523 CSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEAT 582
S S E G S SDT G + + P Q + E
Sbjct: 3335 SSGSQASDSE------GHSEESDTQSVSGHGQ---AGPHQQSHQE--------------- 3370
Query: 583 SPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNG 642
A+D G V E+ GR G+ +GS + + R ++
Sbjct: 3371 --SARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ 3428
Query: 643 GAKETSHASLPQPEPPGGGGS-------KGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSR 695
++T P G GS + +G ++S+ +G + +G SR
Sbjct: 3429 EGQDTIRGH-PGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASR 3487
Query: 696 --TEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLL 753
+S R+S+ ++ + S Q GQ G T + ++ S
Sbjct: 3488 QTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDS-- 3545
Query: 754 QEVLQGYHHHPDRRYSRSTQEHQGMA--GSLEGTTRPNVLVSQTNELASRGLLNKSIGSL 811
QG+ +R +++ H+G A S +G+ P S + A G + + S
Sbjct: 3546 ----QGHSEDSERWSGSASRNHRGSAQEQSRDGSRHP---TSHHEDRAGHG--HSAESSR 3596
Query: 812 LENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDIS 871
H E S A + + +SSA E GS ++ +
Sbjct: 3597 QSGTHHA--ENSSGGQAASSHE--------------QARSSAGERHGSHHQQSA------ 3634
Query: 872 PLRQIVRDPGAHS-LGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKS---QSGQ 927
D HS +GH A + + + + SQ+ G +T+ S Q+G
Sbjct: 3635 -------DSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGP 3687
Query: 928 IKEEDFEQSKSQASFNNKKSGDHCHPPSI--KHESYRGNASPG-----AATHDSLSDYGP 980
++ E ++ +++ + +SG + S + ES G A P + H+ D
Sbjct: 3688 HQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSR 3747
Query: 981 QDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFS 1040
+ + G G R G R S YH+ S RS G HH H T
Sbjct: 3748 HSASQEGQDTIRGHPGSRRGGRQGS---YHE------QSVDRSGHSGS--HH--SHTTSQ 3794
Query: 1041 ERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDW 1100
R++ S + S + + + G + ++Q R Q E
Sbjct: 3795 GRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSR 3854
Query: 1101 SSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVR--SPLKNDKDGMMYGPPVGTYHDPSAQ 1158
S ++ + P S R+ + R S + +DG + G+ H +A
Sbjct: 3855 RSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRH---PGSSHRDTAS 3911
Query: 1159 EAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRY 1212
+ SD K E H S Q+S + S +S G P SS Y
Sbjct: 3912 HVQSSPVQSDSSTAK--EHGHFSSLSQDSAYH-----SGIQSRGSPHSSSSYHY 3958
Score = 66.2 bits (160), Expect = 3e-10
Identities = 321/1675 (19%), Positives = 556/1675 (33%), Gaps = 209/1675 (12%)
Query: 5 REQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGT-GGSSGS--SGSGSGGGRRG 61
R +S G Q S+ ++ SSR Q + + G + GG GS S + G G
Sbjct: 484 RTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSG 543
Query: 62 AAAAAAAMASETSGHQGYQGFR---------KEAGDFYYMAGNKDPVTTGTPQPPQRRPS 112
+ + + G G R +++GD +G++ + +
Sbjct: 544 SHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQV 603
Query: 113 GPVQSYGPP----QGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQ 168
G QS GP QGSS S+GH + + SG +H+ GSAQ Q
Sbjct: 604 GQGQSSGPRTSRNQGSSVSQDSDSQGH-SEDSERWSGSASRNHH----------GSAQEQ 652
Query: 169 QQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSS----HLQPMQRPSTLPSSAAGY 224
+ S+ + + + + T +SSS R S + +
Sbjct: 653 SRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRH 712
Query: 225 QLRVGQFGQHYQSSASSSSSSSFPSPQRFSQS-------GQSYDGSYNVNAGSQYEGHNV 277
QL+ +H + +SS+ S R S G S D +G GH+
Sbjct: 713 QLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQ 772
Query: 278 GSNAQAYGTQS--------NYSYQPQSMKNFEQAK----IPQGTQQGQQQQQPQQQQH-- 323
S+ ++ +S ++ YQ + K E + G +QG +Q +
Sbjct: 773 QSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHS 832
Query: 324 PSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCS 383
SQ + + G +++ V H + + S A S S
Sbjct: 833 ASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA-----SRGQS 887
Query: 384 STPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLS--PTPSMMPSPNSHAAGFKGFGLE 441
+ S T Q GS GSR+ +S S S + +G +
Sbjct: 888 GSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVS 947
Query: 442 GVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNS 501
+ S +++ N + Q + P+ R ADS S
Sbjct: 948 QDSDSEGHSEDSERWSGSASR--NHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQS 1005
Query: 502 EGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSS------------DTTYK 549
G+ E A S + SS E G R +Q + S S D+ +
Sbjct: 1006 -GTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHW 1064
Query: 550 GGASEKAGSSPAQGAQNEPPRLNA--SPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVI 607
G + +A S +++ ++ +++ A+D G V
Sbjct: 1065 GSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTH 1124
Query: 608 VSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNK 667
E+ GR G+ +GS + + R ++ ++T A G++
Sbjct: 1125 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAH------------PGSR 1172
Query: 668 NGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQY 727
G +H+ + +SGHS + T+ S + S G + R+ S Q
Sbjct: 1173 RGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA----------SHGQSGSRSAS--RQT 1220
Query: 728 PTGQEKGDFTGH-GERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTT 786
++ GD + H G R + + G R SR HQG + S + +
Sbjct: 1221 RKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSR----HQGSSVSQDSDS 1276
Query: 787 RPNVLVSQTNELASRGLLNKSIGSLLE-------NPHWGPWERKSSSTAPEMKQINLTDY 839
+ S +E S GS E +P + +R S + + + + T +
Sbjct: 1277 ERH---SDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHH 1333
Query: 840 PIPRKFEIEPQSSAHEPGGSLSE--RRSVICDISPLRQIVRDPGAHS-LGHMSADTRIGR 896
+SS+H S E R S Q D HS +GH A + +
Sbjct: 1334 ---------TESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRD 1384
Query: 897 NDRLNPTLSQSVILPGGLVSMETKLKS---QSGQIKEEDFEQSKSQASFNNKKSGDHCHP 953
+ + SQ G +T+ S Q+G ++ E ++ Q+ ++ +S +
Sbjct: 1385 SGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQ 1444
Query: 954 PSI--KHESYRGNASPGAA---------THDSLSDYGPQDSRPTPMRRVPGRV-GGREG- 1000
S + ES G +P +S QD + T +R PG GGR+G
Sbjct: 1445 VSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDT-IRGHPGSSRGGRQGS 1503
Query: 1001 -----MRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPN 1055
+ S YH + S G G P + E++ S H+
Sbjct: 1504 YHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSG-PRSASRQTRNEEQSGDGSRHS----G 1558
Query: 1056 SETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHR 1115
S + A + H+ S+ ++ Q + + S S + +A+++
Sbjct: 1559 SRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNH 1618
Query: 1116 QEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPV------GTYHDPSAQEAGRCLMSSDG 1169
R+ R R+P + +D +G GT H + +G SS
Sbjct: 1619 YGSAREQSRHGS-----RNPRSHQEDRASHGHSAESSRQSGTRH--AETSSGGQAASSQE 1671
Query: 1170 LPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQS 1229
+HGS+ Q + T + S G S + +D G +E + +
Sbjct: 1672 QARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDT 1731
Query: 1230 SKPGSVMLRLPGQEDH--SSQNPLIMRR-RVRSFISPIPSKRQSQDVKNSSTEDKGRLLH 1286
+ P Q+ H S++ R R SF+ + + QS+ + G
Sbjct: 1732 QSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQR 1791
Query: 1287 SSKEGADKAFNSYAHLSHSQDIKSIP-----KRDSSKDLPSPDSRNCPA---VTLTSPAK 1338
S E A + A I+ P R S S DS TS +
Sbjct: 1792 SRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQER 1851
Query: 1339 TKILPPRKG-RGLKLEAIVQKITSPNIRRSAS-SNSAEAGGDTVTLDDILSLKSGPP--- 1393
+ + + G R + + +K + R S S + A + D+ + +S P
Sbjct: 1852 SDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTS 1911
Query: 1394 -EGGSVAVQDA-------DIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRG----SV 1441
GS QD+ D E+ G + + + A ++ P S E R S
Sbjct: 1912 RNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSA 1971
Query: 1442 DDKVKTET-HAETVTAG---------KEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIF 1491
D ++ T H E+ + G + G + Q ++ R G G A
Sbjct: 1972 DSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAV 2031
Query: 1492 PDSKNVPPVGILAPEANPKAEEKENDTVT----ISPKQEGFPPKGYFPSGKKKGR 1542
DS + G A ++ +E+ + +V+ P Q+ SG+ GR
Sbjct: 2032 RDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGR 2086
Score = 65.9 bits (159), Expect = 4e-10
Identities = 180/873 (20%), Positives = 302/873 (34%), Gaps = 162/873 (18%)
Query: 481 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540
P+ R S ADS S G+ E + A S + SS E G +Q S
Sbjct: 336 PRSHDEDRASHGHSADSSRQS-GTRHAETSSRGQTASSHEQARSSPGERHGSGHQQ-SAD 393
Query: 541 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600
S+ T +G AS +G+ + S A+ E S + +S G +
Sbjct: 394 SSRHSATGRGQASSAVSDRGHRGS-------SGSQASDSEGHSENSDTQSVSGHGKAGLR 446
Query: 601 EKTVGVIVSREAMTGRVEKPGGQDKGS-------QEDDPAATQRPPSNGG--------AK 645
+++ +E+ GR + G+ S ++ D A + S GG A+
Sbjct: 447 QQS-----HQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQAR 501
Query: 646 ETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTS---RTEPSKSP 702
++S S Q G G+ G +H+ + +SGHS + T+ R++ S
Sbjct: 502 DSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQ 561
Query: 703 GSLRYSYK---------DSFGSAVPRNVSGFPQYPTGQ--EKGDFTGHGERKGRNEKFPS 751
R + + D + R+ Q + + + G G R RN+
Sbjct: 562 SGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSV 621
Query: 752 LLQEVLQGYHHHPDRRYSRSTQEHQGMA--GSLEGTTRPNVLVSQTNELASRGLLNKSIG 809
QG+ +R +++ H G A S +G+ P S + A G
Sbjct: 622 SQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPR---SHHEDRAGHG------- 671
Query: 810 SLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICD 869
H RKS + + N + E + +SSA E GS + +S
Sbjct: 672 ------HSADSSRKSGTRHTQ----NSSSGQAASSHE-QARSSAGERHGSRHQLQSA--- 717
Query: 870 ISPLRQIVRDPGAHS-LGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKS---QS 925
D HS GH A + + + + SQ+ G +T+ S Q+
Sbjct: 718 ---------DSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQA 768
Query: 926 GQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRP 985
G ++ E ++ ++ +++SG + S +S + G +T + Q
Sbjct: 769 GHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQ---- 824
Query: 986 TPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANR 1045
R+ R S SQ D + ++ PG SR HH E++
Sbjct: 825 -----------ARDNSR-HSASQ--DGQDTIRGHPGSSRRGRQGSHH--------EQSVD 862
Query: 1046 SSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSA 1105
S H + ++H++T + D + G + R ++ SGS
Sbjct: 863 RSGH----------SGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSR 912
Query: 1106 QGVIA----------AAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDP 1155
+ A Q + EG R S RQ + + + +D + H
Sbjct: 913 HHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRG 972
Query: 1156 SAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPP 1215
SAQE R HGS+ + D + A SS ++ G P
Sbjct: 973 SAQEQSR----------------HGSRHPRSHHEDRAGHGHSADSS--------RQSGTP 1008
Query: 1216 H-ETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVK 1274
H ET G A ++ S PG E H S++ + S S IP ++ S V+
Sbjct: 1009 HAETSSGGQAASSHEQARSS-----PG-ERHGSRH---QQSADSSRHSGIPRRQASSAVR 1059
Query: 1275 NSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQD 1307
+S S EG + ++ + H QD
Sbjct: 1060 DSGHWGSSGSQASDSEGHSEESDTQSVSGHGQD 1092
Score = 53.5 bits (127), Expect = 2e-06
Identities = 272/1430 (19%), Positives = 458/1430 (32%), Gaps = 183/1430 (12%)
Query: 3 SFREQSSYHGN-----QQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGG 57
S E + HG+ +QS + SSR + S + Q + G GS S
Sbjct: 1959 SHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHE-QARSSAGERHGSHHQLQSADSS 2017
Query: 58 GRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQS 117
G A+ A SGH+GY G +A D + + D T + +GP Q
Sbjct: 2018 RHSGIGHGQASSAVRDSGHRGYSG--SQASDSEGHSEDSD-----TQSVSAQGKAGPHQQ 2070
Query: 118 YGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYT-GPFSPGSAQYQQQASSQQQ 176
+ S+ G S G G F Q S +H Q + T G +P + Q Q Q
Sbjct: 2071 --SHKESARGQSGESSGRSGSFLYQVS-----THEQSESTHGQSAPSTGGRQGSHYDQAQ 2123
Query: 177 ---QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQ 233
+ Q Q + H P P G+ S Q + R S + +
Sbjct: 2124 DSSRHSASQEGQDTIRGH-PGPSRGGRQGSHQE--QSVDRSGHSGSHHSHTTSQGRSDAS 2180
Query: 234 HYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEG--HNVGSNAQAYGTQ---- 287
QS + S+S ++ Q S G + GS++ A S + H++ Q+ G +
Sbjct: 2181 RGQSGSRSASRKTYDKEQ--SGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRP 2238
Query: 288 --SNYSYQPQSMKNFEQAKIPQGTQQ-----GQQQQQPQQQQHPSQHVMQYTNAATKLPL 340
S+ S S + E ++ G+ Q+Q +HP H
Sbjct: 2239 RGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAES 2298
Query: 341 QSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ 400
Q G ++ H+ + + QS S + G
Sbjct: 2299 SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS----------RHSGIGH 2348
Query: 401 GSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALS 460
G R+ + + S S +S G G ++ + + S
Sbjct: 2349 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 2408
Query: 461 TQVANLPNTVQHMLLSDALTPQKKTS---KRPSSSKKADSCTNSEGSSQPEEQLKSPMAE 517
+ + V S++ + TS ++ S K+A + S + ++ +
Sbjct: 2409 GRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGS 2468
Query: 518 SLDGGCSSSSEDQGERVRQLSGQSTS--SDTTYKGGASEKAGSSPAQGAQNEPPRLNAS- 574
S G S E +R SG S S S TT +G + G S ++ A + S
Sbjct: 2469 SSGGRQGSHYEQLVDR----SGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSG 2524
Query: 575 PAAREEATSPGAKDMPLSSDGNPKVNE-KTVGVIVSREAMTGRVEKPGGQDKGSQEDDPA 633
+R + S G+ +V + ++ G SR G +G ED
Sbjct: 2525 DGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRN--WGSSFSQDSDSQGHSEDSER 2582
Query: 634 ATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFT 693
+G A H S + G + ++ H+ + + QSG
Sbjct: 2583 ------WSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSG--------- 2627
Query: 694 SRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKG--RNEKFPS 751
+R + S G S++ + SA R+ S Q + GHG+ R+
Sbjct: 2628 TRHTQTSSGGQAASSHEQARSSAGERHGS-HHQQSADSSRHSGIGHGQASSAVRDSGHRG 2686
Query: 752 LLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNV--LVSQTNELASRGLLNKSIG 809
H + ++S H G AGS + + + + +T+ + L S
Sbjct: 2687 YSGSQASDNEGHSEDSDTQSVSAH-GQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTH 2745
Query: 810 SLLENPH-W-GPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVI 867
E+ H W GP R + E Q D + + PG S R+
Sbjct: 2746 EQSESSHGWTGPSTRGRQGSRHEQAQ----DSSRHSASQDGQDTIRGHPGSSRGGRQGYH 2801
Query: 868 CDISPLRQIVRDPGAHSLGHMSADTRIGRND----------------------------- 898
+ S D HS H S T GR+D
Sbjct: 2802 HEHSV------DSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSG 2855
Query: 899 ------RLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCH 952
+ +S+ G + + Q + ++ + S+ S S H
Sbjct: 2856 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 2915
Query: 953 PPSIKHESYRGNASPGAATHDSLS-DYGPQDSRPTPMRRVPGRVGGR--------EGMRG 1003
S + + G+ P + D + SR + R GG+ G
Sbjct: 2916 HGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAG 2975
Query: 1004 RSPSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAY 1063
+H + G G + H +S +++S + S +S+T + +
Sbjct: 2976 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYS--GSQASDNEGHSEDSDTQSVSA 3033
Query: 1064 HANTRAH--AYGDPNAGLNSQL--HYKRQMYQ----QQPEEYKDWSSGSAQGVIAAAQHR 1115
H +H ++ + G + + H +YQ +Q E W+ S +G + +
Sbjct: 3034 HGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQ 3093
Query: 1116 QEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGM 1175
+ + Q D +R G G G +H+ S +G ++G
Sbjct: 3094 AQDSSRHSASQYGQDTIRG-----HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQG- 3147
Query: 1176 ELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPHETDGHG----LAEATQSSK 1231
+ + + Q SR T + SG S R+ HE H ++A Q
Sbjct: 3148 --RSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRH---HEASTHADISRHSQAVQGQS 3202
Query: 1232 PGSVMLRLPG--------QEDHSSQNPLIMRRRVRSFISPIPSK-RQSQDVKNSSTEDKG 1282
GS R G E HS + R+ + + R S ED+
Sbjct: 3203 EGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRA 3262
Query: 1283 RLLHSSKEG-------ADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDS 1325
HS+ A+ + A SH Q S +R S+ S DS
Sbjct: 3263 GHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS 3312
Score = 42.0 bits (97), Expect = 0.006
Identities = 90/437 (20%), Positives = 144/437 (32%), Gaps = 66/437 (15%)
Query: 3 SFREQS---SYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGR 59
S +EQS S H + HG S + GG SS S G R
Sbjct: 3566 SAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGER 3625
Query: 60 RGA--------------AAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQ 105
G+ A+ A SGH+G G +A D + + D T
Sbjct: 3626 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSG--SQASDSEGHSEDSD-----TQS 3678
Query: 106 PPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQD----YTGPFS 161
+GP Q Q S+ G G G G F Q S +H Q + GP +
Sbjct: 3679 VSAHGQAGPHQQ--SHQESTRGRSAGRSGRSGSFLYQVS-----THEQSESAHGRAGPST 3731
Query: 162 PGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSA 221
G + + + + Q Q + H P + S H Q + R S
Sbjct: 3732 GGRQGSRHEQARDSSRHSASQEGQDTIRGH---PGSRRGGRQGSYHEQSVDRSGHSGSHH 3788
Query: 222 AGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEG--HNVGS 279
+ + H QS + S+S + Q S G + GS + A +Q + H+
Sbjct: 3789 SHTTSQGRSDASHGQSGSRSASRETRNEEQ--SGDGSRHSGSRHHEASTQADSSRHSQSG 3846
Query: 280 NAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQ-----------GQQQQQPQQQQHPSQHV 328
++ G++ + ++ + P+ +++ ++Q +HP
Sbjct: 3847 QGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSH 3906
Query: 329 MQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSC--SSTP 386
+ P+QS S + H +FS +S S S +QS SS+
Sbjct: 3907 RDTASHVQSSPVQSD-----------SSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSS 3955
Query: 387 SPLMQTGENLQCGQGSV 403
G Q GQ +
Sbjct: 3956 YHYQSEGTERQKGQSGL 3972
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
sapiens]
Length = 2231
Score = 82.0 bits (201), Expect = 5e-15
Identities = 174/692 (25%), Positives = 238/692 (34%), Gaps = 144/692 (20%)
Query: 9 SYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGG--GRRGAAAAA 66
SY G SYP+ S+ S Q+Q GG ++G G G G + AAA+
Sbjct: 374 SYGG---SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430
Query: 67 AAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQ----------PPQRRPSGPVQ 116
A A++ H DP+ PQ PQ+ P
Sbjct: 431 AWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG 490
Query: 117 SYGPP---------QGSSFGNQYGSEGHVGQFQAQHSGLGGVSHY----QQDYTG----- 158
SYGPP QG + G G + Q Q+ G GVS Y QQ Y
Sbjct: 491 SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQY-GQQGVSGYCQQGQQPYYSQQPQP 549
Query: 159 PFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLP 218
P P AQY S Q+ Q Q Q + Q+ Y + P A G+P +L +RPS+LP
Sbjct: 550 PHLPPQAQYLPSQSQQRYQPQ-QDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLP 608
Query: 219 SSAAGYQ-LRVGQFGQHYQS-SASSSSSS----SFPSPQRFSQSGQSYDGSYNVNAGSQY 272
+ L G + SAS S+SS S P+ FS + S
Sbjct: 609 DLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSP 668
Query: 273 EGHNVGSNA------------------QAYGTQSNYSYQP---QSMKNFEQA------KI 305
G VGSN Q G+QS S P QS E+ +
Sbjct: 669 VGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRN 728
Query: 306 PQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQVG---QYNQPEVP 353
PQ Q G QQ P HPS Q ++ T P SQ G Y++P
Sbjct: 729 PQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY 788
Query: 354 VRSPMQFHQNFSP--------------ISNPSPAASVVQSPSC------------SSTPS 387
P + P S P A + + PS S TPS
Sbjct: 789 SGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPS 848
Query: 388 PLMQTGENLQCGQG-SVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGV--P 444
G + Q G G PM + NR Q + + S S F G G+
Sbjct: 849 ---SPGMSQQGGPGMGPPMPTVNRKAQ-EAAAAVMQAAANSAQSRQGSFPGMNQSGLMAS 904
Query: 445 EKRLTDPGLSSLSALSTQV-------ANLPNTVQHMLLSDALTPQK-----------KTS 486
+ P +S S ++TQ A + ++ + L+D ++P + K
Sbjct: 905 SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEE 964
Query: 487 KRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDT 546
P K+ +S+G SQP P+ + +S S G+ S SS
Sbjct: 965 GTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGD-----ESDSISSPG 1019
Query: 547 TYKGGASEKAGSSPAQGAQ--------NEPPR 570
K +S K+ SS G + NEP R
Sbjct: 1020 WPKTPSSPKSSSSTTTGEKITKVYELGNEPER 1051
Score = 69.7 bits (169), Expect = 3e-11
Identities = 139/598 (23%), Positives = 200/598 (33%), Gaps = 109/598 (18%)
Query: 42 GGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGHQGYQGF------------------- 82
GG+GG G G+G+GG GA AAAAA A+ +G G G+
Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319
Query: 83 ------------------RKEAGDFYYMAGNKDPVTTGTPQPPQ--RRPSGPVQSYGPPQ 122
AG F AG + TP Q PS ++SYG
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379
Query: 123 GSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQ 182
+ + Q Q+Q + G + QQ G G Q A++ QQ
Sbjct: 380 -PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG-MGLGKDMGAQYAAASPAWAAAQQ 437
Query: 183 LRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSS 242
+SH + T P S PM P + Y + Q QSS
Sbjct: 438 ------RSHPAMSPGTPGPTMGRSQGSPMD-PMVMKRPQL-YGMGSNPHSQPQQSSPYPG 489
Query: 243 SSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQ 302
S P PQR+ Q + AG QY + YG Q Y +Q
Sbjct: 490 GSYGPPGPQRYPIGIQG--RTPGAMAGMQYPQQQM---PPQYGQQGVSGY-------CQQ 537
Query: 303 AKIPQGTQQGQQQQQPQQQQH-PSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFH 361
+ P +QQ Q P Q Q+ PSQ +Y SQ G + + P+ H
Sbjct: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD----MSQEGYGTRSQPPLAPGKPNH 593
Query: 362 QNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSV-PMGSRNRILQ--LMPQL 418
++ + I P++ S S P+ T + GS G ++ Q P
Sbjct: 594 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 653
Query: 419 SPTPSMMP-SPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLP-----NTVQH 472
SP S +P P+ G V + +S S +Q+ P + H
Sbjct: 654 SPHLSSIPGGPSPSPVG------SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 707
Query: 473 MLLSDALTPQKK-----TSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSS 527
LS + PQ++ T + P ++ T S P SP + + G SS
Sbjct: 708 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP-----SPGGQ-MHAGISSF- 760
Query: 528 EDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPG 585
Q ++S TY S+ QG + PP + P+A PG
Sbjct: 761 ------------QQSNSSGTYGPQMSQYG----PQGNYSRPPAYSGVPSASYSGPGPG 802
Score = 38.5 bits (88), Expect = 0.064
Identities = 221/1109 (19%), Positives = 358/1109 (32%), Gaps = 169/1109 (15%)
Query: 302 QAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFH 361
Q ++ Q QQ QQQQQ QQQQ QH + N+ L G QP + P
Sbjct: 49 QQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNS-----LGGAGGGAPQPGPDMEQPQHGG 103
Query: 362 QNFSPISNPS--PAASVVQSPSCSSTPSPLM---QTGENLQCGQGSVPMGSRNRILQLMP 416
S + P ++ P P M G G G+ +G++ + +P
Sbjct: 104 AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGA--LGTQQPPV-AVP 160
Query: 417 QLSPTPSMMPSPNSH------AAGFKG------FGLEGVPEKRLTDPGLSSLSALSTQVA 464
P+ +P N++ A+G G F G + PG+ + + S A
Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQ----SPGMGMMHSASAAAA 216
Query: 465 NLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCS 524
P ++ + S P + + P S+ G GG
Sbjct: 217 GAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG----------------GGGG 260
Query: 525 SSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP 584
S G G + A+ AG G + R++
Sbjct: 261 GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--- 317
Query: 585 GAKDMPLSSDGNPKVNEKTVGVIVSR-EAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGG 643
G M G +++ G + G+ + P G + + + S GG
Sbjct: 318 GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGG 377
Query: 644 A-KETSHASLPQPEP--PGGGGSKGNKNGDNNSNHNGEGNGQ---SGHSAAGPGFTS--- 694
+ E S S P P P P + G G G+ + ++AA P + +
Sbjct: 378 SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ 437
Query: 695 RTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQ-YPTG-------QEKGDFTGHGERKGRN 746
R+ P+ SPG+ + S GS + V PQ Y G Q+ + G
Sbjct: 438 RSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497
Query: 747 EKFPSLLQ----EVLQGYHHHPDRRYSRSTQE------HQGMAGSLEGTTRPNVLVSQTN 796
+++P +Q + G + + + Q+ QG +P L Q
Sbjct: 498 QRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ 557
Query: 797 ELASRGLLNKSIGSLLENPHWGPWERKSSSTA-PEMKQINLTDYPIPRKFEIEPQSSAHE 855
L S+ + +G + + P + +NL P S
Sbjct: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617
Query: 856 PGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGG-- 913
P G+ + S + S G S + + +P LS +PGG
Sbjct: 618 PTGTEATLSSAVS---------ASGSTSSQGDQSNPAQSPFSPHASPHLSS---IPGGPS 665
Query: 914 ---LVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAA 970
+ S +S+SG I S+ PP + ES +
Sbjct: 666 PSPVGSPVGSNQSRSGPISPASIPGSQMPP-----------QPPGSQSES---------S 705
Query: 971 THDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDP 1030
+H +LS +PM + G + G + R +QY MSP S PGG
Sbjct: 706 SHPALSQ--------SPMPQERGFMAGTQ--RNPQMAQYGPQQTGPSMSPHPS--PGG-- 751
Query: 1031 HHMNPHMTFSERANRSSLHTP----FSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYK 1086
M+ ++ +++N S + P + P ++ + +Y P G+ +
Sbjct: 752 -QMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMG--ISAN 808
Query: 1087 RQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRV-RSPLKNDKDGMMY 1145
QM+ Q P + G + + G + P SP + + G
Sbjct: 809 NQMHGQGPSQ--------PCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860
Query: 1146 GPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPG 1205
GPP+ T + AQEA +M + N + + +S L +SP
Sbjct: 861 GPPMPTV-NRKAQEAAAAVMQA--AANSAQSRQGSFPGMNQS--GLMASSSPYSQPMNNS 915
Query: 1206 MSSQKRYGPPHETDGHGLAEATQSSKPGSVML---RLPGQEDHSSQNPLIMRRRVRSFIS 1262
S PP + +A A +S SV L PG+ S+ PL ++ + +
Sbjct: 916 SSLMNTQAPP-----YSMAPAMVNSSAASVGLADMMSPGE----SKLPLPLKADGKEEGT 966
Query: 1263 PIPSKRQSQDVKN---SSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKS--IPKRDSS 1317
P P + + S G L S A S H S I S PK SS
Sbjct: 967 PQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSS 1026
Query: 1318 KDLPSPDSRNCPAVTLTSPAKTKILPPRK 1346
P S +T + P RK
Sbjct: 1027 ---PKSSSSTTTGEKITKVYELGNEPERK 1052
Score = 36.2 bits (82), Expect = 0.32
Identities = 34/124 (27%), Positives = 46/124 (37%), Gaps = 26/124 (20%)
Query: 166 QYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
Q+QQQ QQQQQQ QQ +Q ++ L A G ++ Q S+A G
Sbjct: 54 QFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGG-- 111
Query: 226 LRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVN--AGSQYEGHNVGSNAQA 283
+ P P S+ G D + AG +YE +G A
Sbjct: 112 ------------------QADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLG----A 149
Query: 284 YGTQ 287
GTQ
Sbjct: 150 LGTQ 153
Score = 35.8 bits (81), Expect = 0.42
Identities = 58/257 (22%), Positives = 85/257 (33%), Gaps = 22/257 (8%)
Query: 118 YGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFS-PGSAQYQQQASSQQQ 176
YGPP G+ Y + + Q Q ++ GG Y+GP P QY S ++
Sbjct: 1362 YGPPAKRHEGDMYNMQ-YSSQQQEMYNQYGG------SYSGPDRRPIQGQYPYPYSRERM 1414
Query: 177 QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRP-STLPSSAAGYQLRVGQFG--Q 233
Q Q Q+H PQ G P SSS P Q + YQ R G G Q
Sbjct: 1415 QGPGQ------IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQ 1468
Query: 234 HYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQ 293
+ + QR + Q +V+ Y + Q +Y
Sbjct: 1469 APPYPGMNRTDDMMVPDQRINHESQ---WPSHVSQRQPYMSSSASMQPITRPPQPSYQTP 1525
Query: 294 PQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVP 353
P + +A P Q+ + + + P M+ +P G QP P
Sbjct: 1526 PSLPNHISRAPSPASFQRSLENRM-SPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP-P 1583
Query: 354 VRSPMQFHQNFSPISNP 370
+R + F S P
Sbjct: 1584 IRREITFPPGSVEASQP 1600
Score = 33.1 bits (74), Expect = 2.7
Identities = 62/239 (25%), Positives = 85/239 (35%), Gaps = 40/239 (16%)
Query: 6 EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAA 65
E SS+ QS + G + +P+ AQ TG S S G G ++
Sbjct: 703 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQ--QTGPSMSPHPSPGGQMHAGISSF 760
Query: 66 AAAMASETSGHQGYQGFRKEAGDFYYMAGN--KDPVTTGTPQPPQRRPSGPVQSYGPPQG 123
+ +S T G Q Q Y GN + P +G P SGP GP G
Sbjct: 761 QQSNSSGTYGPQMSQ---------YGPQGNYSRPPAYSGVPSASY---SGP----GPGMG 804
Query: 124 SSFGNQYGSEGHVGQFQAQHSG-LGGVSHYQQDYTG------PFSPGSAQY--------- 167
S NQ +G A G + + + G P SPG +Q
Sbjct: 805 ISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPM 864
Query: 168 -QQQASSQQQQQQVQQLRQQLYQSHQ---PLPQATGQPASSSSHLQPMQRPSTLPSSAA 222
+Q+ V Q QS Q P +G ASSS + QPM S+L ++ A
Sbjct: 865 PTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQA 923
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
sapiens]
Length = 2178
Score = 80.9 bits (198), Expect = 1e-14
Identities = 200/858 (23%), Positives = 285/858 (33%), Gaps = 175/858 (20%)
Query: 9 SYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGG--GRRGAAAAA 66
SY G SYP+ S+ S Q+Q GG ++G G G G + AAA+
Sbjct: 374 SYGG---SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430
Query: 67 AAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQ----------PPQRRPSGPVQ 116
A A++ H DP+ PQ PQ+ P
Sbjct: 431 AWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG 490
Query: 117 SYGPP---------QGSSFGNQYGSEGHVGQFQAQHSGLGGVS---------HYQQDYTG 158
SYGPP QG + G G + Q Q+ G GVS +Y Q
Sbjct: 491 SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQY-GQQGVSGYCQQGQQPYYSQQPQP 549
Query: 159 PFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLP 218
P P AQY + SQQ+ Q Q + Q+ Y + P A G+P +L +RPS+LP
Sbjct: 550 PHLPPQAQY-LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLP 608
Query: 219 S-SAAGYQLRVG-----QFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQY 272
S + L G S SS S P+ FS + S
Sbjct: 609 DLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSP 668
Query: 273 EGHNVGSN------------------AQAYGTQSNYSYQP---QSMKNFEQA------KI 305
G VGSN Q G+QS S P QS E+ +
Sbjct: 669 VGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRN 728
Query: 306 PQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQV---GQYNQPEVP 353
PQ Q G QQ P HPS Q ++ T P SQ G Y++P
Sbjct: 729 PQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY 788
Query: 354 VRSPMQFHQNFSP--------------ISNPSPAASVVQSPSC------------SSTPS 387
P + P S P A + + PS S TPS
Sbjct: 789 SGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPS 848
Query: 388 PLMQTGENLQCGQG-SVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGV--P 444
G + Q G G PM + NR Q + + S S F G G+
Sbjct: 849 ---SPGMSQQGGPGMGPPMPTVNRKAQ-EAAAAVMQAAANSAQSRQGSFPGMNQSGLMAS 904
Query: 445 EKRLTDPGLSSLSALSTQV-------ANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADS 497
+ P +S S ++TQ A + ++ + L+D ++P + P KAD
Sbjct: 905 SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLP---LKADG 961
Query: 498 CTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSD--------TTYK 549
EG+ QPE + K SSSS GE++ ++ + T+
Sbjct: 962 --KEEGTPQPESKSKK----------SSSSTTTGEKITKVYELGNEPERKLWVDRYLTFM 1009
Query: 550 GGASEKAGSSPAQGAQ--------------NEPPRLNASPAAREEATSPGAKDMPLSSDG 595
S PA G + ++N + RE AT+ ++ SS
Sbjct: 1010 EERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATN---LNVGTSSSA 1066
Query: 596 NPKVNEKTVGVIVSREAMTGRVEKPGGQ--DKGSQEDDPAATQRPPSNGGAKETSHASLP 653
+ ++ + + + E R E+P + G + P P+N G SL
Sbjct: 1067 ASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSG-------SLQ 1119
Query: 654 QPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSF 713
P+ P GS + + G G S T P + D
Sbjct: 1120 GPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDP------FSDVS 1173
Query: 714 GSAVPRNVSGFPQYPTGQ 731
S+ P+ S P P Q
Sbjct: 1174 DSSFPKRNSMTPNAPYQQ 1191
Score = 69.7 bits (169), Expect = 3e-11
Identities = 139/598 (23%), Positives = 200/598 (33%), Gaps = 109/598 (18%)
Query: 42 GGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGHQGYQGF------------------- 82
GG+GG G G+G+GG GA AAAAA A+ +G G G+
Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319
Query: 83 ------------------RKEAGDFYYMAGNKDPVTTGTPQPPQ--RRPSGPVQSYGPPQ 122
AG F AG + TP Q PS ++SYG
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379
Query: 123 GSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQ 182
+ + Q Q+Q + G + QQ G G Q A++ QQ
Sbjct: 380 -PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG-MGLGKDMGAQYAAASPAWAAAQQ 437
Query: 183 LRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSS 242
+SH + T P S PM P + Y + Q QSS
Sbjct: 438 ------RSHPAMSPGTPGPTMGRSQGSPMD-PMVMKRPQL-YGMGSNPHSQPQQSSPYPG 489
Query: 243 SSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQ 302
S P PQR+ Q + AG QY + YG Q Y +Q
Sbjct: 490 GSYGPPGPQRYPIGIQG--RTPGAMAGMQYPQQQM---PPQYGQQGVSGY-------CQQ 537
Query: 303 AKIPQGTQQGQQQQQPQQQQH-PSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFH 361
+ P +QQ Q P Q Q+ PSQ +Y SQ G + + P+ H
Sbjct: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD----MSQEGYGTRSQPPLAPGKPNH 593
Query: 362 QNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSV-PMGSRNRILQ--LMPQL 418
++ + I P++ S S P+ T + GS G ++ Q P
Sbjct: 594 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 653
Query: 419 SPTPSMMP-SPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLP-----NTVQH 472
SP S +P P+ G V + +S S +Q+ P + H
Sbjct: 654 SPHLSSIPGGPSPSPVG------SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 707
Query: 473 MLLSDALTPQKK-----TSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSS 527
LS + PQ++ T + P ++ T S P SP + + G SS
Sbjct: 708 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP-----SPGGQ-MHAGISSF- 760
Query: 528 EDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPG 585
Q ++S TY S+ QG + PP + P+A PG
Sbjct: 761 ------------QQSNSSGTYGPQMSQYG----PQGNYSRPPAYSGVPSASYSGPGPG 802
Score = 40.4 bits (93), Expect = 0.017
Identities = 203/1039 (19%), Positives = 342/1039 (32%), Gaps = 161/1039 (15%)
Query: 302 QAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFH 361
Q ++ Q QQ QQQQQ QQQQ QH + N+ L G QP + P
Sbjct: 49 QQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNS-----LGGAGGGAPQPGPDMEQPQHGG 103
Query: 362 QNFSPISNPS--PAASVVQSPSCSSTPSPLM---QTGENLQCGQGSVPMGSRNRILQLMP 416
S + P ++ P P M G G G+ +G++ + +P
Sbjct: 104 AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGA--LGTQQPPV-AVP 160
Query: 417 QLSPTPSMMPSPNSH------AAGFKG------FGLEGVPEKRLTDPGLSSLSALSTQVA 464
P+ +P N++ A+G G F G + PG+ + + S A
Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQ----SPGMGMMHSASAAAA 216
Query: 465 NLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCS 524
P ++ + S P + + P S+ G GG
Sbjct: 217 GAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG----------------GGGG 260
Query: 525 SSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP 584
S G G + A+ AG G + R++
Sbjct: 261 GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--- 317
Query: 585 GAKDMPLSSDGNPKVNEKTVGVIVSR-EAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGG 643
G M G +++ G + G+ + P G + + + S GG
Sbjct: 318 GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGG 377
Query: 644 A-KETSHASLPQPEP--PGGGGSKGNKNGDNNSNHNGEGNGQ---SGHSAAGPGFTS--- 694
+ E S S P P P P + G G G+ + ++AA P + +
Sbjct: 378 SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ 437
Query: 695 RTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQ-YPTG-------QEKGDFTGHGERKGRN 746
R+ P+ SPG+ + S GS + V PQ Y G Q+ + G
Sbjct: 438 RSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497
Query: 747 EKFPSLLQ----EVLQGYHHHPDRRYSRSTQE------HQGMAGSLEGTTRPNVLVSQTN 796
+++P +Q + G + + + Q+ QG +P L Q
Sbjct: 498 QRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ 557
Query: 797 ELASRGLLNKSIGSLLENPHWGPWERKSSSTA-PEMKQINLTDYPIPRKFEIEPQSSAHE 855
L S+ + +G + + P + +NL P S
Sbjct: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617
Query: 856 PGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGG-- 913
P G+ + S + S G S + + +P LS +PGG
Sbjct: 618 PTGTEATLSSAVS---------ASGSTSSQGDQSNPAQSPFSPHASPHLSS---IPGGPS 665
Query: 914 ---LVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAA 970
+ S +S+SG I S+ PP + ES +
Sbjct: 666 PSPVGSPVGSNQSRSGPISPASIPGSQMPP-----------QPPGSQSES---------S 705
Query: 971 THDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDP 1030
+H +LS +PM + G + G + R +QY MSP S PGG
Sbjct: 706 SHPALSQ--------SPMPQERGFMAGTQ--RNPQMAQYGPQQTGPSMSPHPS--PGG-- 751
Query: 1031 HHMNPHMTFSERANRSSLHTP----FSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYK 1086
M+ ++ +++N S + P + P ++ + +Y P G+ +
Sbjct: 752 -QMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMG--ISAN 808
Query: 1087 RQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRV-RSPLKNDKDGMMY 1145
QM+ Q P + G + + G + P SP + + G
Sbjct: 809 NQMHGQGPSQ--------PCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860
Query: 1146 GPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPG 1205
GPP+ T + AQEA +M + N + + +S L +SP
Sbjct: 861 GPPMPTV-NRKAQEAAAAVMQA--AANSAQSRQGSFPGMNQS--GLMASSSPYSQPMNNS 915
Query: 1206 MSSQKRYGPPHETDGHGLAEATQSSKPGSVML---RLPGQEDHSSQNPLIMRRRVRSFIS 1262
S PP + +A A +S SV L PG+ S+ PL ++ + +
Sbjct: 916 SSLMNTQAPP-----YSMAPAMVNSSAASVGLADMMSPGE----SKLPLPLKADGKEEGT 966
Query: 1263 PIPSKRQSQDVKNSSTEDK 1281
P P + + +++T +K
Sbjct: 967 PQPESKSKKSSSSTTTGEK 985
Score = 36.2 bits (82), Expect = 0.32
Identities = 37/140 (26%), Positives = 50/140 (35%), Gaps = 20/140 (14%)
Query: 150 SHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQ 209
+H+ + A QQ QQQQQQ QQ +QQ Q P+ + Q
Sbjct: 32 AHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQ 91
Query: 210 PMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVN-- 267
P G + Q G S+A + P P S+ G D +
Sbjct: 92 P------------GPDMEQPQHGGAKDSAAGGQADP--PGPPLLSKPGDEDDAPPKMGEP 137
Query: 268 AGSQYEGHNVGSNAQAYGTQ 287
AG +YE +G A GTQ
Sbjct: 138 AGGRYEHPGLG----ALGTQ 153
Score = 35.8 bits (81), Expect = 0.42
Identities = 58/257 (22%), Positives = 85/257 (33%), Gaps = 22/257 (8%)
Query: 118 YGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFS-PGSAQYQQQASSQQQ 176
YGPP G+ Y + + Q Q ++ GG Y+GP P QY S ++
Sbjct: 1309 YGPPAKRHEGDMYNMQ-YSSQQQEMYNQYGG------SYSGPDRRPIQGQYPYPYSRERM 1361
Query: 177 QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRP-STLPSSAAGYQLRVGQFG--Q 233
Q Q Q+H PQ G P SSS P Q + YQ R G G Q
Sbjct: 1362 QGPGQ------IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQ 1415
Query: 234 HYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQ 293
+ + QR + Q +V+ Y + Q +Y
Sbjct: 1416 APPYPGMNRTDDMMVPDQRINHESQ---WPSHVSQRQPYMSSSASMQPITRPPQPSYQTP 1472
Query: 294 PQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVP 353
P + +A P Q+ + + + P M+ +P G QP P
Sbjct: 1473 PSLPNHISRAPSPASFQRSLENRM-SPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP-P 1530
Query: 354 VRSPMQFHQNFSPISNP 370
+R + F S P
Sbjct: 1531 IRREITFPPGSVEASQP 1547
Score = 33.1 bits (74), Expect = 2.7
Identities = 62/239 (25%), Positives = 85/239 (35%), Gaps = 40/239 (16%)
Query: 6 EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAA 65
E SS+ QS + G + +P+ AQ TG S S G G ++
Sbjct: 703 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQ--QTGPSMSPHPSPGGQMHAGISSF 760
Query: 66 AAAMASETSGHQGYQGFRKEAGDFYYMAGN--KDPVTTGTPQPPQRRPSGPVQSYGPPQG 123
+ +S T G Q Q Y GN + P +G P SGP GP G
Sbjct: 761 QQSNSSGTYGPQMSQ---------YGPQGNYSRPPAYSGVPSASY---SGP----GPGMG 804
Query: 124 SSFGNQYGSEGHVGQFQAQHSG-LGGVSHYQQDYTG------PFSPGSAQY--------- 167
S NQ +G A G + + + G P SPG +Q
Sbjct: 805 ISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPM 864
Query: 168 -QQQASSQQQQQQVQQLRQQLYQSHQ---PLPQATGQPASSSSHLQPMQRPSTLPSSAA 222
+Q+ V Q QS Q P +G ASSS + QPM S+L ++ A
Sbjct: 865 PTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQA 923
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 79.3 bits (194), Expect = 3e-14
Identities = 191/857 (22%), Positives = 283/857 (33%), Gaps = 89/857 (10%)
Query: 7 QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTG-GSSGSSGSGSGGGRRGAAAA 65
Q Q SY Q GSS+ + ++ FG G GSS S+G G G G +A
Sbjct: 760 QHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAG 819
Query: 66 AAAMAS-----------ETSGHQ---GYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRP 111
S E+ HQ G G Y G+ T+G Q R
Sbjct: 820 FGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQ--HRSS 877
Query: 112 SGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGG-VSHYQQDYTGPFSPGSAQ---Y 167
SG +G GS G G H G Q+SG G S Q G GS+Q Y
Sbjct: 878 SGQYSGFGQ-HGSGSGQSSGFGQH-GTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGY 935
Query: 168 QQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLR 227
Q SS Q Q R QS GQ S S + + ++G+
Sbjct: 936 GQHGSSSGQTFGFGQHRSGSGQS-----SGFGQHGSGSGQSSGFGQHESGSGKSSGFGQH 990
Query: 228 VGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEG---HNVGSN-AQA 283
+ Q S SS S Q S SGQ+ + ++ QY G H GS+ +
Sbjct: 991 ESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSG 1050
Query: 284 YGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVM---QYTNAATKLPL 340
+G S Q +E + + GQ Q QH Q + P
Sbjct: 1051 FGQHGTGSGQSSGFGQYESRS--RQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPG 1108
Query: 341 QSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ 400
Q + Q F Q+ S S A SS + ++ CGQ
Sbjct: 1109 SGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQ 1168
Query: 401 ---GSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLE-------GVPEKRLTD 450
GS P S + + S + + S + + GF +G G E + +
Sbjct: 1169 HESGSGPTTSFGQHVSGSDNFSSSGQHI-SDSGQSTGFGQYGSGSGQSTGLGQGESQQVE 1227
Query: 451 PGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQ 510
G + T NT +H + Q T R + +++ NS+ S+ +
Sbjct: 1228 SGSTVHGRQETTHGQTINTTRHSQSGQGQSTQ--TGSRVTRRRRSSQSENSD--SEVHSK 1283
Query: 511 LKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSS--DTTYKGGASEKAGSSPAQGAQNEP 568
+ +E + S G VR+ G + DTT G + G S G++
Sbjct: 1284 VSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGH--GQSTQTGSRTSG 1341
Query: 569 PRLNASPAAREEATSPGAKDMPLS-----SDGNPKVNEKTVGVIVSREAMTGRVEKPGGQ 623
+ + A + G P S S + E V E G+ + G
Sbjct: 1342 RQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGH 1401
Query: 624 DKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGG-----------GSKGNKNGDNN 672
+TQR G + + H+ E GG G G+++G++
Sbjct: 1402 GHSGHGQ---STQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESG 1458
Query: 673 SN---HNGEGNGQSGHSAAGPGF---TSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQ 726
S +G +GQ+G + + S S + G + +S S V SG
Sbjct: 1459 STVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVH---SGGSH 1515
Query: 727 YPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGS-LEGT 785
+G G G + G +E + G R+S S E GS G
Sbjct: 1516 THSGHTHGQ---SGSQHGESESIIHDRHRITHG-QTGDTTRHSYSGHEQTTQTGSRTTGR 1571
Query: 786 TRPNVLVSQTNELASRG 802
R + S +E+ S G
Sbjct: 1572 QRTSHSESTDSEVHSGG 1588
Score = 66.6 bits (161), Expect = 2e-10
Identities = 178/768 (23%), Positives = 258/768 (33%), Gaps = 121/768 (15%)
Query: 7 QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAA 66
QSS +G S + G + E S + + Q+ G+G SSG GSG G+
Sbjct: 702 QSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQH 761
Query: 67 AAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQGSSF 126
+ + ++S Q G + +G Y G++ T+G Q SG QS G Q S
Sbjct: 762 ESRSGQSSYGQHSSGSSQSSG--YGQHGSRQ--TSGFGQ----HGSGSSQSTGFGQYGSG 813
Query: 127 GNQYGSEGHVGQFQAQHSGLG-GVSHYQQDYTGPFSPGSAQ---YQQQASSQQQQQQVQQ 182
Q G G Q SG G S Q G GS+Q Y Q SS Q Q
Sbjct: 814 SGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQ 873
Query: 183 LRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGY-----QLRVGQFGQHYQS 237
R Q GQ S S + T +G+ + +GQH
Sbjct: 874 HRSSSGQY-----SGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSG 928
Query: 238 SA--------SSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEG---HNVGSNA----- 281
S+ SSS +F Q S SGQS + + Q G H GS
Sbjct: 929 SSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFG 988
Query: 282 --QAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLP 339
++ +QSNY Q S + G+ GQ Q + Q+ + +
Sbjct: 989 QHESRSSQSNYG-QHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQY-SGFGQHGSGSD 1046
Query: 340 LQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCG 399
S GQ+ + F + S +S Q S SS S Q G N
Sbjct: 1047 QSSGFGQHG-------TGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSN---- 1095
Query: 400 QGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSAL 459
G + Q P S S S + GFG G + G SS
Sbjct: 1096 -----SGQTSGFGQHRPG-SGQSSGFGQYGSGSGQSSGFGQHG------SGTGKSS---- 1139
Query: 460 STQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESL 519
QH S Q + + S ++ C E S P + + +
Sbjct: 1140 --------GFAQHEYRSG----QSSYGQHGTGSSQSSGCGQHESGSGP----TTSFGQHV 1183
Query: 520 DGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAARE 579
G + SS G+ + SGQST Y G+ + G + Q E ++ R+
Sbjct: 1184 SGSDNFSS--SGQHISD-SGQSTGFG-QYGSGSGQSTGLGQGESQQVES---GSTVHGRQ 1236
Query: 580 EATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPP 639
E T + S + +T + R + SQ ++ +
Sbjct: 1237 ETTHGQTINTTRHSQSGQGQSTQTGSRVTRRR-------------RSSQSENSDSEVHSK 1283
Query: 640 SNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSG----HSAAGPGFTSR 695
+ E H GS K+G G +GQ G H +G G +++
Sbjct: 1284 VSHRHSEHIHTQ---------AGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQ 1334
Query: 696 TEPSKSPGSLRYSYKDSFGSAVPRNVSGFP--QYPTGQEKGDFTGHGE 741
T S++ G R+S+ D+ S V VS P Q T + G G E
Sbjct: 1335 T-GSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESE 1381
Score = 57.8 bits (138), Expect = 1e-07
Identities = 94/367 (25%), Positives = 136/367 (37%), Gaps = 48/367 (13%)
Query: 13 NQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASE 72
+ QS + HGSS S + + Q+ G+G SSG GSG G+ +++ +
Sbjct: 460 SSQSLGYDQHGSS-----SGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQ 514
Query: 73 TSGHQGYQGFRKEAGDF-----------YYMAGNKDPVTTGTPQPPQRRPSGPVQ-SYGP 120
+SG + ++ F Y G+ ++G Q R SG Q G
Sbjct: 515 SSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGS 574
Query: 121 PQGSSFGNQYGS-EGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQ 179
Q + FG QYGS G F SG G S + Q + G + Y Q +S Q
Sbjct: 575 GQSTGFG-QYGSGSGQSSGFGQHGSGSGQSSGFGQHES---RSGQSSYGQHSSGSSQSSG 630
Query: 180 VQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRV---GQ---FGQ 233
Q + S Q GQ S SS + + ++G+ V GQ FGQ
Sbjct: 631 YGQ-----HGSRQ--TSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQ 683
Query: 234 HYQSSASSS-------SSSSFPSPQRFSQSGQ-SYDGSYNVNAG--SQYEGHNVGS-NAQ 282
H S SS SS S Q S SGQ S G + +++G S + H GS +
Sbjct: 684 HESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSS 743
Query: 283 AYGTQSNYSYQPQSMKNFE--QAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPL 340
+G + S Q E + G Q QH S+ + +
Sbjct: 744 GFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQ 803
Query: 341 QSQVGQY 347
+ GQY
Sbjct: 804 STGFGQY 810
Score = 57.4 bits (137), Expect = 1e-07
Identities = 90/365 (24%), Positives = 128/365 (35%), Gaps = 38/365 (10%)
Query: 7 QSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFG----GTGGSSGSSGSGSGGGRRGA 62
Q Q SY Q GSS+ + ++ FG G+G S+G GSG G+
Sbjct: 533 QHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSG 592
Query: 63 AAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQ------ 116
+ + ++SG ++ ++ + +G+ ++G Q R+ SG Q
Sbjct: 593 FGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ--SSGYGQHGSRQTSGFGQHGSGSS 650
Query: 117 --------SYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQ 168
G Q S FG G F QH G S Y Q G S S+ Y
Sbjct: 651 QSTGFGQYGSGSGQSSGFGQHVSGSGQSSGF-GQHESRSGHSSYGQHGFG--SSQSSGYG 707
Query: 169 QQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGY---Q 225
Q SS Q Q QS + GQ S S + + ++G+ +
Sbjct: 708 QHGSSSGQTSGFGQHELSSGQS-----SSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHE 762
Query: 226 LRVGQ--FGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQA 283
R GQ +GQH S+ SS S Q S GQ GS QY G G +A
Sbjct: 763 SRSGQSSYGQHSSGSSQSSGYGQHGSRQT-SGFGQHGSGSSQSTGFGQY-GSGSGQSA-G 819
Query: 284 YGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQ 343
+G + S Q E + GQ Q QH + +S
Sbjct: 820 FGQHGSGSGQSSGFGQHESRS--HQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSS 877
Query: 344 VGQYN 348
GQY+
Sbjct: 878 SGQYS 882
Score = 45.8 bits (107), Expect = 4e-04
Identities = 76/342 (22%), Positives = 130/342 (38%), Gaps = 53/342 (15%)
Query: 6 EQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSG------SGGGR 59
+ S HG +S E HG++ G TG +SG S SG SG
Sbjct: 1828 QAGSQHGESESIVDERHGTTH---------------GQTGDTSGHSQSGHGQSTQSGSST 1872
Query: 60 RGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRR---PSGPVQ 116
G + + +S++ H G G +G + A ++ + T + +G
Sbjct: 1873 TGRRRSGHSESSDSEVHSG--GSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTT 1930
Query: 117 SYG-PPQGSSFGNQYGSEGHVGQFQAQHS---GLGGVSHYQQDYT----GPFSP--GSAQ 166
+G P G + + G G +++S G GVSH +T G P GS+
Sbjct: 1931 EHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSV 1990
Query: 167 YQQQASSQQQQQQVQQLRQQLY-QSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
+++ ++ Q + + QS Q + TG+ AS S + S + + +G+
Sbjct: 1991 HERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGH- 2049
Query: 226 LRVGQFGQHYQSSASS------SSSSSFPSPQRFSQSGQSYDGSY-NVNAGSQYEGHNVG 278
GQ G + S SS ++ R + SG + AG + GH+
Sbjct: 2050 -AHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSES 2108
Query: 279 SNAQAYG----TQSNYSYQPQSMKNFEQAKI---PQGTQQGQ 313
S+++ + T S ++Y ++ E QGT GQ
Sbjct: 2109 SDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQ 2150
Score = 35.8 bits (81), Expect = 0.42
Identities = 48/196 (24%), Positives = 70/196 (35%), Gaps = 19/196 (9%)
Query: 2 QSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQA-QMFQNFGGTGGSSGSSGSGSGGGRR 60
QS + S G Q+S E S E SP + G G SGSSG G G
Sbjct: 2164 QSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTH 2223
Query: 61 GAAAAAAAMASETSGHQGYQGFRK--EAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSY 118
G A G +G R G + + + + + G+ SG +Q
Sbjct: 2224 GQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGS-----HTHSGHIQG- 2277
Query: 119 GPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHY------QQDYTGPFSPGSAQYQQQAS 172
Q S Q GS H G+ + H G + + Q TG S ++ +Q +S
Sbjct: 2278 ---QAGSQQRQPGSTVH-GRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQSHSS 2333
Query: 173 SQQQQQQVQQLRQQLY 188
+Q+ Q + Y
Sbjct: 2334 ERQRHGSSQVWKHGSY 2349
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
sapiens]
Length = 2191
Score = 76.3 bits (186), Expect = 3e-13
Identities = 201/870 (23%), Positives = 285/870 (32%), Gaps = 186/870 (21%)
Query: 9 SYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGG--GRRGAAAAA 66
SY G SYP+ S+ S Q+Q GG ++G G G G + AAA+
Sbjct: 374 SYGG---SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430
Query: 67 AAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQ----------PPQRRPSGPVQ 116
A A++ H DP+ PQ PQ+ P
Sbjct: 431 AWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG 490
Query: 117 SYGPP-------------QGSSFGNQYGSEGHVGQFQAQHS--------GLGGVSHY--- 152
SYGPP G+ G QY + G + + G GVS Y
Sbjct: 491 SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQ 550
Query: 153 -QQDYTG-----PFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSS 206
QQ Y P P AQY S Q+ Q Q Q + Q+ Y + P A G+P
Sbjct: 551 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQ-QDMSQEGYGTRSQPPLAPGKPNHEDL 609
Query: 207 HLQPMQRPSTLPS-SAAGYQLRVG-----QFGQHYQSSASSSSSSSFPSPQRFSQSGQSY 260
+L +RPS+LP S + L G S SS S P+ FS +
Sbjct: 610 NLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPH 669
Query: 261 DGSYNVNAGSQYEGHNVGSN------------------AQAYGTQSNYSYQP---QSMKN 299
S G VGSN Q G+QS S P QS
Sbjct: 670 LSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMP 729
Query: 300 FEQA------KIPQGTQQGQQQQQPQQQQHPS---------QHVMQYTNAATKLPLQSQV 344
E+ + PQ Q G QQ P HPS Q ++ T P SQ
Sbjct: 730 QERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 789
Query: 345 ---GQYNQPEVPVRSPMQFHQNFSP--------------ISNPSPAASVVQSPSC----- 382
G Y++P P + P S P A + + PS
Sbjct: 790 GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849
Query: 383 -------SSTPSPLMQTGENLQCGQG-SVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAG 434
S TPS G + Q G G PM + NR Q + + S S
Sbjct: 850 PFPGNMSSMTPS---SPGMSQQGGPGMGPPMPTVNRKAQ-EAAAAVMQAAANSAQSRQGS 905
Query: 435 FKGFGLEGV--PEKRLTDPGLSSLSALSTQV-------ANLPNTVQHMLLSDALTPQKKT 485
F G G+ + P +S S ++TQ A + ++ + L+D ++P +
Sbjct: 906 FPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESK 965
Query: 486 SKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSD 545
P KAD EG+ QPE + K SSSS GE++ ++ +
Sbjct: 966 LPLP---LKADG--KEEGTPQPESKSKK----------SSSSTTTGEKITKVYELGNEPE 1010
Query: 546 --------TTYKGGASEKAGSSPAQGAQ--------------NEPPRLNASPAAREEATS 583
T+ S PA G + ++N + RE AT+
Sbjct: 1011 RKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATN 1070
Query: 584 PGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQ--DKGSQEDDPAATQRPPSN 641
++ SS + ++ + + + E R E+P + G + P P+N
Sbjct: 1071 ---LNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPAN 1127
Query: 642 GGAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKS 701
G SL P+ P GS + + G G S T
Sbjct: 1128 SG-------SLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHD 1180
Query: 702 PGSLRYSYKDSFGSAVPRNVSGFPQYPTGQ 731
P + D S+ P+ S P P Q
Sbjct: 1181 P------FSDVSDSSFPKRNSMTPNAPYQQ 1204
Score = 68.2 bits (165), Expect = 8e-11
Identities = 139/601 (23%), Positives = 202/601 (33%), Gaps = 102/601 (16%)
Query: 42 GGTGGSSGSSGSGSGGGRRGAAAAAAAMASETSGHQGYQGF------------------- 82
GG+GG G G+G+GG GA AAAAA A+ +G G G+
Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319
Query: 83 ------------------RKEAGDFYYMAGNKDPVTTGTPQPPQ--RRPSGPVQSYGPPQ 122
AG F AG + TP Q PS ++SYG
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379
Query: 123 GSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQ 182
+ + Q Q+Q + G + QQ G G Q A++ QQ
Sbjct: 380 -PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG-MGLGKDMGAQYAAASPAWAAAQQ 437
Query: 183 LRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSS 242
+SH + T P S PM P + Y + Q QSS
Sbjct: 438 ------RSHPAMSPGTPGPTMGRSQGSPMD-PMVMKRPQL-YGMGSNPHSQPQQSSPYPG 489
Query: 243 SSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGT--QSNYSYQPQSMKNF 300
S P PQR+ Q + AG QY +A T Y Q + +
Sbjct: 490 GSYGPPGPQRYPIGIQG--RTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGY 547
Query: 301 -EQAKIPQGTQQGQQQQQPQQQQH-PSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPM 358
+Q + P +QQ Q P Q Q+ PSQ +Y SQ G + + P+
Sbjct: 548 CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD----MSQEGYGTRSQPPLAPGK 603
Query: 359 QFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSV-PMGSRNRILQ--LM 415
H++ + I P++ S S P+ T + GS G ++ Q
Sbjct: 604 PNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFS 663
Query: 416 PQLSPTPSMMP-SPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLP-----NT 469
P SP S +P P+ G V + +S S +Q+ P +
Sbjct: 664 PHASPHLSSIPGGPSPSPVG------SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSES 717
Query: 470 VQHMLLSDALTPQKK-----TSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCS 524
H LS + PQ++ T + P ++ T S P SP + + G S
Sbjct: 718 SSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP-----SPGGQ-MHAGIS 771
Query: 525 SSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP 584
S Q ++S TY S+ QG + PP + P+A P
Sbjct: 772 SF-------------QQSNSSGTYGPQMSQYG----PQGNYSRPPAYSGVPSASYSGPGP 814
Query: 585 G 585
G
Sbjct: 815 G 815
Score = 37.4 bits (85), Expect = 0.14
Identities = 47/215 (21%), Positives = 74/215 (34%), Gaps = 31/215 (14%)
Query: 506 QPEEQLKSPMAESLD-GGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGS---SPA 561
Q ++Q + P++ + GG + G + Q Q + + GG ++ G S
Sbjct: 67 QQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQ--PQHGGAKDSAAGGQADPPGPPLLSKP 124
Query: 562 QGAQNEPPRLNASPAAREEATSPGA---KDMPLSSDGN-------PKVNEKTVGVIVSRE 611
+ PP++ R E GA + P++ G P+ N +
Sbjct: 125 GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG 184
Query: 612 AMTGRV----EKPGGQDK---GSQEDDPAATQRPPSNGGAKETSHASLPQPE-------- 656
GR ++ GGQ G AA P + + SH P +
Sbjct: 185 GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYS 244
Query: 657 PPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPG 691
PG GG G G + G G G +G AG G
Sbjct: 245 RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279
Score = 36.6 bits (83), Expect = 0.24
Identities = 203/1053 (19%), Positives = 345/1053 (32%), Gaps = 176/1053 (16%)
Query: 302 QAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFH 361
Q ++ Q QQ QQQQQ QQQQ QH + N+ L G QP + P
Sbjct: 49 QQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNS-----LGGAGGGAPQPGPDMEQPQHGG 103
Query: 362 QNFSPISNPS--PAASVVQSPSCSSTPSPLM---QTGENLQCGQGSVPMGSRNRILQLMP 416
S + P ++ P P M G G G+ +G++ + +P
Sbjct: 104 AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGA--LGTQQPPV-AVP 160
Query: 417 QLSPTPSMMPSPNSH------AAGFKG------FGLEGVPEKRLTDPGLSSLSALSTQVA 464
P+ +P N++ A+G G F G + PG+ + + S A
Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQ----SPGMGMMHSASAAAA 216
Query: 465 NLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCS 524
P ++ + S P + + P S+ G GG
Sbjct: 217 GAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG----------------GGGG 260
Query: 525 SSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSP 584
S G G + A+ AG G + R++
Sbjct: 261 GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--- 317
Query: 585 GAKDMPLSSDGNPKVNEKTVGVIVSR-EAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGG 643
G M G +++ G + G+ + P G + + + S GG
Sbjct: 318 GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGG 377
Query: 644 A-KETSHASLPQPEP--PGGGGSKGNKNGDNNSNHNGEGNGQ---SGHSAAGPGFTS--- 694
+ E S S P P P P + G G G+ + ++AA P + +
Sbjct: 378 SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ 437
Query: 695 RTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQ-YPTG-------QEKGDFTGHGERKGRN 746
R+ P+ SPG+ + S GS + V PQ Y G Q+ + G
Sbjct: 438 RSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497
Query: 747 EKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPN--VLVSQTNELASRGLL 804
+++P +Q G + + ++ S + T + ++ Q + G
Sbjct: 498 QRYPIGIQGRTPG---------AMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYC 548
Query: 805 NKS----IGSLLENPHWGPWERKSSSTAPEMKQ----INLTDYPIPRKFEIEPQSSAHEP 856
+ + PH P + S + + Q ++ Y + + P HE
Sbjct: 549 QQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHED 608
Query: 857 GGSL-SERRSVICDIS------------PLRQIVRDPGA-HSLGHMSADTRIGRNDRLNP 902
+ ER S + D+S L V G+ S G S + + +P
Sbjct: 609 LNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASP 668
Query: 903 TLSQSVILPGG-----LVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPP-SI 956
LS +PGG + S +S+SG I S+ +S HP S
Sbjct: 669 HLSS---IPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQ 725
Query: 957 KHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKL 1016
G + ++ YGPQ + P+
Sbjct: 726 SPMPQERGFMAGTQRNPQMAQYGPQQTGPS------------------------------ 755
Query: 1017 KMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHTP----FSPNSETLASAYHANTRAHAY 1072
MSP S PGG M+ ++ +++N S + P + P ++ + +Y
Sbjct: 756 -MSPHPS--PGG---QMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASY 809
Query: 1073 GDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRV 1132
P G+ + QM+ Q P + G + + G + P
Sbjct: 810 SGPGPGMG--ISANNQMHGQGPSQ--------PCGAVPLGRMPSAGMQNRPFPGNMSSMT 859
Query: 1133 -RSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDL 1191
SP + + G GPP+ T + AQEA +M + N + + +S L
Sbjct: 860 PSSPGMSQQGGPGMGPPMPTV-NRKAQEAAAAVMQA--AANSAQSRQGSFPGMNQS--GL 914
Query: 1192 SRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVML---RLPGQEDHSSQ 1248
+SP S PP + +A A +S SV L PG+ S+
Sbjct: 915 MASSSPYSQPMNNSSSLMNTQAPP-----YSMAPAMVNSSAASVGLADMMSPGE----SK 965
Query: 1249 NPLIMRRRVRSFISPIPSKRQSQDVKNSSTEDK 1281
PL ++ + +P P + + +++T +K
Sbjct: 966 LPLPLKADGKEEGTPQPESKSKKSSSSTTTGEK 998
Score = 36.2 bits (82), Expect = 0.32
Identities = 37/140 (26%), Positives = 50/140 (35%), Gaps = 20/140 (14%)
Query: 150 SHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQ 209
+H+ + A QQ QQQQQQ QQ +QQ Q P+ + Q
Sbjct: 32 AHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQ 91
Query: 210 PMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVN-- 267
P G + Q G S+A + P P S+ G D +
Sbjct: 92 P------------GPDMEQPQHGGAKDSAAGGQADP--PGPPLLSKPGDEDDAPPKMGEP 137
Query: 268 AGSQYEGHNVGSNAQAYGTQ 287
AG +YE +G A GTQ
Sbjct: 138 AGGRYEHPGLG----ALGTQ 153
Score = 35.8 bits (81), Expect = 0.42
Identities = 58/257 (22%), Positives = 85/257 (33%), Gaps = 22/257 (8%)
Query: 118 YGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFS-PGSAQYQQQASSQQQ 176
YGPP G+ Y + + Q Q ++ GG Y+GP P QY S ++
Sbjct: 1322 YGPPAKRHEGDMYNMQ-YSSQQQEMYNQYGG------SYSGPDRRPIQGQYPYPYSRERM 1374
Query: 177 QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRP-STLPSSAAGYQLRVGQFG--Q 233
Q Q Q+H PQ G P SSS P Q + YQ R G G Q
Sbjct: 1375 QGPGQ------IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQ 1428
Query: 234 HYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQ 293
+ + QR + Q +V+ Y + Q +Y
Sbjct: 1429 APPYPGMNRTDDMMVPDQRINHESQ---WPSHVSQRQPYMSSSASMQPITRPPQPSYQTP 1485
Query: 294 PQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVP 353
P + +A P Q+ + + + P M+ +P G QP P
Sbjct: 1486 PSLPNHISRAPSPASFQRSLENRM-SPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP-P 1543
Query: 354 VRSPMQFHQNFSPISNP 370
+R + F S P
Sbjct: 1544 IRREITFPPGSVEASQP 1560
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 75.9 bits (185), Expect = 4e-13
Identities = 87/392 (22%), Positives = 151/392 (38%), Gaps = 74/392 (18%)
Query: 1548 NKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEP 1607
+K +Q QPPPPPP+ P P S K + R R++ P + RK+ + VE
Sbjct: 6 DKSVEQPQPPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGKTAVED 65
Query: 1608 QEPEIKLKYA-TQPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKG 1666
++ L+ T+ + +T+ K +S AEE+ + ++ ++
Sbjct: 66 EDSMDGLETTETETIVETEIKEQS---------------------AEEDAEAEVDNSKQL 104
Query: 1667 QRSLTPPPSSTESKALPASSFMLQGPVVTESSVMGHLVC-CLCGKWASYRNMGDLFGPFY 1725
+L S + +L + V E+ + L C CG+ +S GDL
Sbjct: 105 IPTLQRSVSEESANSLVS--------VGVEAKISEQLCAFCYCGEKSSL-GQGDL----- 150
Query: 1726 PQDYAAT----LPKNPPPKRATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLA 1781
+ + T LP P ++ SNG+ +K Q S
Sbjct: 151 -KQFRITPGFILPWRNQPSNKKDIDDN--------SNGT------------YEKMQNSAP 189
Query: 1782 AHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQ 1841
R +R+ RS + C +T+ +S+ K + G P+ +
Sbjct: 190 RKQRGQRKERSPQ--------QNIVSCVSVSTQTASDDQA--GKLWDELSLVGLPDA-ID 238
Query: 1842 IPELPLDSNEFWVHEGCILWANGI-YLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCY 1900
I L + W H C+ W+ G+ + L + +A+ +C+ C+ GAT+ C
Sbjct: 239 IQALFDSTGTCWAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCC 298
Query: 1901 NKGCSFRYHYPCAIDADCLLHEENFSVRCPKH 1932
+ C+ YHYPCA A + + CP+H
Sbjct: 299 EEKCTQMYHYPCAAGAGTFQDFSHIFLLCPEH 330
Score = 71.2 bits (173), Expect = 9e-12
Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Query: 1851 EFWVHEGCILWANGIYLV-CGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYH 1909
+ WVH C LW+ +Y G L ++ AL +MKC C + GAT GC+ C+ YH
Sbjct: 4425 DLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYH 4484
Query: 1910 YPCAIDADCLLHEENFSVRCPKHK 1933
+ CAI A C+ ++ ++ CP HK
Sbjct: 4485 FTCAIKAQCMFFKDK-TMLCPMHK 4507
Score = 43.5 bits (101), Expect = 0.002
Identities = 112/433 (25%), Positives = 159/433 (36%), Gaps = 89/433 (20%)
Query: 293 QPQSMKNFEQAKIPQGTQQGQQ----QQQPQQQQHPSQHVMQYTNAAT-----KLPLQSQ 343
Q K+ +QAKI + TQ+ +Q QQQ QQQQ SQH++ + + T + PL Q
Sbjct: 1755 QQMRQKSKQQAKI-EATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQ 1813
Query: 344 VGQYNQPEVPVRSPMQ-FHQNF---SPISNPSPAAS-----VVQSPSCSSTPS--PLMQT 392
G N SP Q FH+ P S P+ +S Q+P PS P+ +
Sbjct: 1814 PGNGNM------SPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDS 1867
Query: 393 GENLQCGQGSVPM----GSRNR--ILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEK 446
Q Q P GS N + P + P P H+ + P +
Sbjct: 1868 LSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRN---SAAPVE 1924
Query: 447 RLTDPGLSSLS---ALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSK--KADSCTNS 501
T LSS+S ++ AN P+ V+ L S + T +K P + + D S
Sbjct: 1925 NCTP--LSSVSRPLQMNETTANRPSPVRD-LCSSSTTNNDPYAKPPDTPRPVMTDQFPKS 1981
Query: 502 EGSSQ----PEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAG 557
G S+ E+ K P+A + S RQ S + A +G
Sbjct: 1982 LGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTP--APLDSG 2039
Query: 558 SSPAQGAQNEPP--------------RLNASPAAREEAT-------SPGAKDMPLSS--- 593
P + PP RL+ P R T S + P S
Sbjct: 2040 PGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPL 2099
Query: 594 DGNPKVNEKTVGVIVSRE-AMTGRVEKPGGQDKGSQEDDPAATQRP------PSNGGAKE 646
+P VNE SR + G + +P QD SQ P T RP S+G A+
Sbjct: 2100 TPHPAVNESFAH--PSRAFSQPGTISRPTSQDPYSQ---PPGTPRPVVDSYSQSSGTARS 2154
Query: 647 TSHASLPQPEPPG 659
+ P +PPG
Sbjct: 2155 NTD---PYSQPPG 2164
Score = 43.5 bits (101), Expect = 0.002
Identities = 94/457 (20%), Positives = 158/457 (34%), Gaps = 63/457 (13%)
Query: 306 PQGTQQ-GQQQQQPQQQQ----HPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSP--M 358
PQ QQ GQ QQ QQ PS TN ++ S V + P +PV SP
Sbjct: 3473 PQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVP--DSPSIPVGSPNFS 3530
Query: 359 QFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPM------GSRNRIL 412
Q +S S S V+ + P+ +L CGQ S GS ++
Sbjct: 3531 SVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGSTQSLI 3590
Query: 413 QLMPQLSPTP------SMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLS-ALSTQVAN 465
QL + P + + A K P +T P +S ST +
Sbjct: 3591 QLYSDIIPEEKGKKKRTRKKKRDDDAESTKA---PSTPHSDITAPPTPGISETTSTPAVS 3647
Query: 466 LPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPM--AESLDGGC 523
P+ + +++ P ++ ++ + N +S + + A S
Sbjct: 3648 TPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKL 3707
Query: 524 SSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSS--------PAQGAQNEPPRLNASP 575
S + + E ++ ++ S + E+ GS P AQ+ PP +P
Sbjct: 3708 SMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQS-PPHSAGAP 3766
Query: 576 AAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAAT 635
AA+ ++ + K + + + +N+K G I S + T +D+
Sbjct: 3767 AAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCT--------------KDNKLVE 3812
Query: 636 QRPPSNG----GAKETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPG 691
++ P+ G GA+ P GGS+ K + GE A P
Sbjct: 3813 KQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGE--------KAAPR 3864
Query: 692 FTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYP 728
R + + ++ YS D+F +N P P
Sbjct: 3865 SKKRKKDEEEKQAM-YSSTDTFTHLKQQNNLSNPPTP 3900
Score = 37.0 bits (84), Expect = 0.19
Identities = 114/518 (22%), Positives = 169/518 (32%), Gaps = 127/518 (24%)
Query: 157 TGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQ---PMQR 213
+GP P Q SSQ V Q ++L P T +P + SH Q P +
Sbjct: 2038 SGP-GPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQ 2096
Query: 214 PSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQR-FSQSGQSYDGSYNVNAGSQY 272
P P A + SF P R FSQ G + + + SQ
Sbjct: 2097 PPLTPHPAV---------------------NESFAHPSRAFSQPG-TISRPTSQDPYSQP 2134
Query: 273 EGHN---VGSNAQAYGT-QSN---YSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPS 325
G V S +Q+ GT +SN YS P + P+ T QQPQ + +
Sbjct: 2135 PGTPRPVVDSYSQSSGTARSNTDPYSQPPGT---------PRPTTVDPYSQQPQTPRPST 2185
Query: 326 QHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSST 385
Q + T PV + P P P SV S +T
Sbjct: 2186 QTDLFVT--------------------PVTNQRHSDPYAHPPGTPRPGISVPYSQP-PAT 2224
Query: 386 PSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPT-PSMMPSPNSHAAGFKGFGLEGVP 444
P P + G V M +++ LQ P P + P +
Sbjct: 2225 PRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCS----------Q 2274
Query: 445 EKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGS 504
R PGLS +T + S A P ++ P S ++S G+
Sbjct: 2275 TPRPPGPGLS-------------DTFSRVSPSAARDPYDQSPMTPRSQ------SDSFGT 2315
Query: 505 SQPEEQLKSPMAESLDGG-CSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQG 563
SQ + +G C+SS+ + +Q SG S+ G P G
Sbjct: 2316 SQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSG------------VSQLPGPVPTSG 2363
Query: 564 AQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQ 623
+ +N + A E+ + +K +I+ ++ + G Q
Sbjct: 2364 VTDTQNTVNMAQADTEKL----------------RQRQKLREIILQQQQQK---KIAGRQ 2404
Query: 624 DKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGGG 661
+KGSQ D PA P E + + +P PP G
Sbjct: 2405 EKGSQ-DSPAVPHPGPLQHWQPENVNQAFTRPPPPYPG 2441
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 68.2 bits (165), Expect = 8e-11
Identities = 44/162 (27%), Positives = 64/162 (39%), Gaps = 22/162 (13%)
Query: 1793 EDCGGGPRSLSRGLPCKKAATEGSSEKTVLDSK---PSVPTTSEGGPE--LELQIPELPL 1847
+DC GGP C + + G E + P P S GG E +P L
Sbjct: 56 QDCSGGPVRRCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGGSPGPNEAVLPSEDL 115
Query: 1848 DSNEF----------------WVHEGCILWANGIYLVCG-RLYGLQEALEIAREMKCSHC 1890
F W H C W+ G++ G L G+ +A+ +CSHC
Sbjct: 116 SQIGFPEGLTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHC 175
Query: 1891 QEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPKH 1932
GA++ C + GC YH+PCA + L + + CP+H
Sbjct: 176 TRLGASIPCRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEH 217
Score = 66.6 bits (161), Expect = 2e-10
Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 1851 EFWVHEGCILWANGIYLVCG-RLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYH 1909
+ WVH C LW+ +Y G L ++ AL KCS CQ GAT C C YH
Sbjct: 5055 DLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYH 5114
Query: 1910 YPCAIDADCLLHEENFSVRCPKHKVR 1935
+ CAI A C+ ++ ++ CP HK++
Sbjct: 5115 FACAIRAKCMFFKDK-TMLCPMHKIK 5139
Score = 56.6 bits (135), Expect = 2e-07
Identities = 140/626 (22%), Positives = 205/626 (32%), Gaps = 128/626 (20%)
Query: 103 TPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVS--HYQQDYTGPF 160
+PQPPQ GP GP Q V Q QH G G H Q T
Sbjct: 3791 SPQPPQ----GPQGMLGPAQ-------------VAVLQQQHPGALGPQGPHRQVLMTQSR 3833
Query: 161 SPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSS 220
S Q QQ + V +QQ Q HQ G SHLQ
Sbjct: 3834 VLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGL-----SHLQ----------- 3877
Query: 221 AAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSN 280
Q + GQ S+ S Q+ Q Q Q + +
Sbjct: 3878 ----QSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQL----------QQQQQQQLQQQ 3923
Query: 281 AQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNA--ATKL 338
Q Q Q Q ++ +Q ++ Q QQ QQQQQ QQQQ Q Q ++
Sbjct: 3924 QQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRT 3983
Query: 339 PLQSQVGQYNQPEVPVRSPMQFHQNFSP----------------ISNPSPAASVVQSPSC 382
L Q Q Q + P + Q+FS +P+ ++ + PS
Sbjct: 3984 LLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPST 4043
Query: 383 -SSTPSPLMQTGENLQCGQGSV--PMGSRNRILQLMPQLSPTPS--------MMPSPNS- 430
P + T E++ G V + +++L + PQ P PS +P
Sbjct: 4044 HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQ 4103
Query: 431 -----HAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKT 485
H AG G G L+ S + + P ++ LL PQ+
Sbjct: 4104 QVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLG----PQQPM 4159
Query: 486 SKRPSSS-------KKADSCTNSEG---------SSQPEEQLKSPMAESLDGGCSSSSED 529
+RP + K + +G Q QL+ +A++ S +
Sbjct: 4160 LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219
Query: 530 QGERVRQLSGQSTSSDTTYKGGASEKAG--SSPAQGAQNEPPRLNASPAAREEATSP--- 584
Q + + Q S + ++ G +SP QG P+L P + T P
Sbjct: 4220 QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ---TGPLQE 4276
Query: 585 -GAKDMPLSSDGNPKV----NEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAA----- 634
GA P G P++ + G ++ T P + SQ P++
Sbjct: 4277 LGAGPRP---QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTE 4333
Query: 635 TQRPPSNGGAKETSHASLPQPEPPGG 660
Q PP++ G T P EPP G
Sbjct: 4334 AQLPPTHPG---TPKPQGPTLEPPPG 4356
Score = 51.6 bits (122), Expect = 7e-06
Identities = 123/542 (22%), Positives = 186/542 (34%), Gaps = 63/542 (11%)
Query: 146 LGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQP--LPQATGQPAS 203
L V Q+++T + + QQQ QQQQQQ L S P L + GQ
Sbjct: 3578 LDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLP 3637
Query: 204 SSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGS 263
LQP Q P A G +L G Q +++ Q+ G GS
Sbjct: 3638 GHG-LQPPQGPP--GGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGA---GS 3691
Query: 264 YNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQ--- 320
+G + G+ ++ G S + Q ++ ++ Q QQ QQQQQ QQ
Sbjct: 3692 LAGPSGGFFPGNLA---LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLL 3748
Query: 321 -----QQHPSQHVMQYTNAAT------KLPLQSQVG---QYNQPEVPVRSP--MQFHQNF 364
QQ Q TN A +P S G Q P+ P + P M
Sbjct: 3749 GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQ-PPQGPQGMLGPAQV 3807
Query: 365 SPISNPSPAASVVQSP--SCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTP 422
+ + P A Q P T S ++ + + Q GQG LM T
Sbjct: 3808 AVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQG------------LMGHRLVTA 3855
Query: 423 SMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQ 482
H GL + + ++ G LSA + +L Q L Q
Sbjct: 3856 QQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSA--QPMGSLQQLQQQQQLQQQQQLQ 3913
Query: 483 KKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQST 542
++ ++ ++ Q ++QL+ + L + Q ++ +Q Q
Sbjct: 3914 QQQQQQLQQQQQLQQ--QQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQ 3971
Query: 543 SSDTTYKGGASEKAGSSPAQGAQNE---PPRLNASPAAREEATSPGAKDMPLSSDGNPKV 599
+ SP Q Q + P + A P + +SPGA L G
Sbjct: 3972 QQQMGLLN--QSRTLLSPQQQQQQQVALGPGMPAKPL--QHFSSPGALGPTLLLTGK--- 4024
Query: 600 NEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQ----RPPSNGGAKETSHASLPQP 655
+ TV VS EA G GG + AT+ +P +G ++ PQP
Sbjct: 4025 EQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQP 4084
Query: 656 EP 657
+P
Sbjct: 4085 QP 4086
Score = 35.0 bits (79), Expect = 0.71
Identities = 69/336 (20%), Positives = 115/336 (34%), Gaps = 43/336 (12%)
Query: 349 QPEVPVRSPMQFH----QNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVP 404
+P P SP+ H QN SP S SP A + PS S ++ + + +
Sbjct: 1018 EPLPPQCSPLLQHSLVPQN-SPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETE 1076
Query: 405 MGSRNRILQLMPQL-SPTPSMM-------PSPNSHAAGFKGFGLEGVPEKRLTDPGLSSL 456
S L P SP PS M PSP F G G + P + PG
Sbjct: 1077 KVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQP- 1135
Query: 457 SALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMA 516
+ P ++ L + + + + C + G P E+ + P A
Sbjct: 1136 -----EPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRA 1190
Query: 517 ESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASP- 575
+ + + + V ++S S + G+ GS +G + L S
Sbjct: 1191 PVAP---TPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTD 1247
Query: 576 --AAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPA 633
AR+E + + L +D P+ ++ + + A++G G E +
Sbjct: 1248 VSPARDEGS------LRLCTDSLPETDDSLL--CDAGTAISG----------GKAEGEKG 1289
Query: 634 ATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNG 669
+ P+ K+ +S P P GG G G
Sbjct: 1290 RRRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRGRG 1325
Score = 35.0 bits (79), Expect = 0.71
Identities = 63/236 (26%), Positives = 93/236 (39%), Gaps = 24/236 (10%)
Query: 106 PPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPG-S 164
PP S P S+G Q S G V + + +G+G S + G PG S
Sbjct: 2618 PPAPDGSLPYLSHGASQRS------GITSPVEKREDPGTGMGS-SLATAELPGTQDPGMS 2670
Query: 165 AQYQQQASSQQQQQQVQQL--RQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAA 222
Q + Q+Q+Q++++L RQQ+ ++ L Q A+++ + P PSS A
Sbjct: 2671 GLSQTELEKQRQRQRLRELLIRQQIQRN--TLRQEKETAAAAAGAVGPPGSWGAEPSSPA 2728
Query: 223 GYQLRVGQF---GQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGS 279
QL GQ G +SS S P S S D + +V S
Sbjct: 2729 FEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNS 2788
Query: 280 NAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAA 335
G+Q+ Y P +P Q QQQQ QQQQ + M++ +A
Sbjct: 2789 RQLVGGSQAFYQRAPYP------GSLPL---QQQQQQLWQQQQATAATSMRFAMSA 2835
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 65.1 bits (157), Expect = 6e-10
Identities = 82/284 (28%), Positives = 106/284 (37%), Gaps = 59/284 (20%)
Query: 166 QYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
Q QQQ QQQQQQ QQ +QQ Q+ P+ Q PMQ+P PS A Q
Sbjct: 245 QLQQQ---QQQQQQQQQQQQQALQAQPPIQQP------------PMQQPQPPPSQALPQQ 289
Query: 226 LRVGQFGQHYQSSASSSSSSSFPSPQR--FSQSGQSYDGSYNVNAGSQYEGHNVGSNAQA 283
L+ QH+Q P PQ+ +Q+ S Q + + S AQA
Sbjct: 290 LQQMHHTQHHQPP---------PQPQQPPVAQNQPS-------QLPPQSQTQPLVSQAQA 333
Query: 284 YGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQ----------HVMQYTN 333
Q Y+ P + + P QQ Q Q QQQQ Q V T
Sbjct: 334 LPGQMLYTQPP-----LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITE 388
Query: 334 A--------ATKLPLQSQVGQYNQPEVPV-RSPM-QFHQNFSP-ISNPSPAASVVQSPSC 382
A + P + V +P+ R PM Q Q+ P +S+PSP V S
Sbjct: 389 ALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSM 448
Query: 383 SSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMP 426
P P Q G+ +V G +P SP PS P
Sbjct: 449 PPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP 492
Score = 44.3 bits (103), Expect = 0.001
Identities = 110/499 (22%), Positives = 180/499 (36%), Gaps = 102/499 (20%)
Query: 111 PSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHS----GLGGVSHYQQDYTGPFSPGSAQ 166
P GP QS G GS G +GQ + G G++ + +P +
Sbjct: 103 PRGPGQSLGG---------MGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQL 153
Query: 167 YQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQL 226
QQ + QQQQQQ QQ +QQ Q A+ Q Q+
Sbjct: 154 QLQQVALQQQQQQ-QQFQQQ-------------QQAALQQQQQQQQQ------------- 186
Query: 227 RVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGT 286
Q +Q+ S+ Q+ Q Q Q + H + + Q
Sbjct: 187 ------QQFQAQQSAMQQQFQAVVQQQQQLQQQ----------QQQQQHLIKLHHQ---N 227
Query: 287 QSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQ-------YTNAATKLP 339
Q Q Q ++ Q ++ Q QQ QQQQQ QQQ +Q +Q + LP
Sbjct: 228 QQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287
Query: 340 LQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPS------CSSTPSPLMQTG 393
Q Q + Q P P Q P++ P+ QS + + P ++ T
Sbjct: 288 QQLQQMHHTQHHQPPPQPQQ-----PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Query: 394 ENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEK------- 446
L+ + PM + +Q PQ+ + + + + AA G++ + E
Sbjct: 343 PPLKFVR--APMVVQQPPVQ--PQVQQQQTAVQT--AQAAQMVAPGVQMITEALAQGGMH 396
Query: 447 -RLTDPGLSSLSALSTQVANLPNTVQHML-LSDALTPQKKTSKRPSSSKKADSCTNSEGS 504
R P +++SA+ + +++P Q M +S + P + PS ++ + +
Sbjct: 397 IRARFPPTTAVSAIPS--SSIPLGRQPMAQVSQSSLPMLSS---PSPGQQVQTPQSMPPP 451
Query: 505 SQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGA 564
QP Q P ++ S + + S Q + S T + + + S P+ G
Sbjct: 452 PQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTAR---TPQNFSVPSPGP 508
Query: 565 QNEP--PRLNASPAAREEA 581
N P P SPA +A
Sbjct: 509 LNTPVNPSSVMSPAGSSQA 527
Score = 33.9 bits (76), Expect = 1.6
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 10/75 (13%)
Query: 1549 KQKKQQQPP--PPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVE 1606
+Q Q QPP PP Q PQ P A P+ +Q + +P QP Q P+ +
Sbjct: 261 QQALQAQPPIQQPPMQQPQPPPSQA--LPQQLQQMHHTQHHQPPPQP------QQPPVAQ 312
Query: 1607 PQEPEIKLKYATQPL 1621
Q ++ + TQPL
Sbjct: 313 NQPSQLPPQSQTQPL 327
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 64.7 bits (156), Expect = 8e-10
Identities = 76/263 (28%), Positives = 98/263 (37%), Gaps = 57/263 (21%)
Query: 166 QYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
Q QQQ QQQQQQ QQ +QQ Q+ P+ Q PMQ+P PS A Q
Sbjct: 245 QLQQQ---QQQQQQQQQQQQQALQAQPPIQQP------------PMQQPQPPPSQALPQQ 289
Query: 226 LRVGQFGQHYQSSASSSSSSSFPSPQR--FSQSGQSYDGSYNVNAGSQYEGHNVGSNAQA 283
L+ QH+Q P PQ+ +Q+ S Q + + S AQA
Sbjct: 290 LQQMHHTQHHQPP---------PQPQQPPVAQNQPS-------QLPPQSQTQPLVSQAQA 333
Query: 284 YGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQ 343
Q Y+ P + + P QQ Q Q QQQ Q +Q AA + Q
Sbjct: 334 LPGQMLYTQPP-----LKFVRAPMVVQQPPVQPQVQQQ----QTAVQTAQAAQMVAPGVQ 384
Query: 344 VGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSV 403
V Q + P +S+PSP V S P P Q G+ +V
Sbjct: 385 VSQSSLP---------------MLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNV 429
Query: 404 PMGSRNRILQLMPQLSPTPSMMP 426
G +P SP PS P
Sbjct: 430 SSGPAPSPSSFLPSPSPQPSQSP 452
Score = 48.5 bits (114), Expect = 6e-05
Identities = 113/467 (24%), Positives = 151/467 (32%), Gaps = 146/467 (31%)
Query: 111 PSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHS----GLGGVSHYQQDYTGPFSPGSAQ 166
P GP QS G GS G +GQ + G G++ + +P +
Sbjct: 103 PRGPGQSLGG---------MGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQL 153
Query: 167 YQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQL 226
QQ + QQQQQQ QQ +QQ Q A+ Q Q+
Sbjct: 154 QLQQVALQQQQQQ-QQFQQQ-------------QQAALQQQQQQQQQ------------- 186
Query: 227 RVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGT 286
Q +Q+ S+ Q+ Q Q Q + H + + Q
Sbjct: 187 ------QQFQAQQSAMQQQFQAVVQQQQQLQQQ----------QQQQQHLIKLHHQ---N 227
Query: 287 QSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQ--------------------------- 319
Q Q Q ++ Q ++ Q QQ QQQQQ Q
Sbjct: 228 QQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287
Query: 320 ---QQQHPSQHVMQ---------YTNAATKLPLQSQV-----------GQ--YNQPEVP- 353
QQ H +QH N ++LP QSQ GQ Y QP +
Sbjct: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKF 347
Query: 354 VRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPM------GS 407
VR+PM Q P V Q + T +Q Q S+PM G
Sbjct: 348 VRAPMVVQQ-------PPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQ 400
Query: 408 RNRILQLMPQLSPTPSMMP-SPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANL 466
+ + Q MP P PS P P+S G P L P S Q +
Sbjct: 401 QVQTPQSMPP-PPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSP--------SPQPSQS 451
Query: 467 PNTVQHMLLSDALTPQKKTSKRP---SSSKKADSCTNSEGSSQPEEQ 510
P T A TPQ + P ++ S + GSSQ EEQ
Sbjct: 452 PVT--------ARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQ 490
Score = 37.7 bits (86), Expect = 0.11
Identities = 58/288 (20%), Positives = 103/288 (35%), Gaps = 18/288 (6%)
Query: 1419 PANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGR 1478
P Q+ +++P P S+ + T+ H + ++PP A SQ P +Q +
Sbjct: 268 PPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH-QPPPQPQQPPVAQNQP-SQLPPQSQTQ 325
Query: 1479 PDGSLGGTAP--LIF--PDSKNV-PPVGILAPEANPKAEEKENDTVTISPKQEGFP---- 1529
P S P +++ P K V P+ + P P+ ++++ T Q P
Sbjct: 326 PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQV 385
Query: 1530 PKGYFP--SGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQR-QRRER 1586
+ P S G+ + + QP P P QP P + P P
Sbjct: 386 SQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPS 445
Query: 1587 RKPGAQPRKRKTKQ--AVPIVEPQEPEIKLKYATQPLDKTDAKNKSFYPYIHVVNKC--E 1642
+P P +T Q +VP P + P + A+ + + + ++K
Sbjct: 446 PQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEP 505
Query: 1643 LGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQ 1690
L + I+ E+ + L + + LT P K L L+
Sbjct: 506 LRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALE 553
Score = 33.9 bits (76), Expect = 1.6
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 10/75 (13%)
Query: 1549 KQKKQQQPP--PPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVE 1606
+Q Q QPP PP Q PQ P A P+ +Q + +P QP Q P+ +
Sbjct: 261 QQALQAQPPIQQPPMQQPQPPPSQA--LPQQLQQMHHTQHHQPPPQP------QQPPVAQ 312
Query: 1607 PQEPEIKLKYATQPL 1621
Q ++ + TQPL
Sbjct: 313 NQPSQLPPQSQTQPL 327
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 63.5 bits (153), Expect = 2e-09
Identities = 298/1478 (20%), Positives = 478/1478 (32%), Gaps = 288/1478 (19%)
Query: 184 RQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSS 243
+Q+L SH P + +G+P QP S + Q G+ S+ S
Sbjct: 84 KQELDSSHPP--KQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRS----PSTISLKE 137
Query: 244 SSSFPSPQRFSQSGQSYDGSYNVNAGS-------QYEGHNVGSNAQAYGTQSNYSYQPQS 296
S S + +S VNA S ++ ++ S+++A ++ + Q
Sbjct: 138 SKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETT---KKQK 194
Query: 297 MKNFEQAKIPQGTQQGQQQQQPQQ----QQHPSQHVMQYTNAATKLPLQSQVGQYNQPEV 352
+ EQ K P+G + QQQP + QQ P + +Q + Q QPE
Sbjct: 195 VVQKEQGK-PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQ-------QPE- 245
Query: 353 PVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRIL 412
++S P P Q+P PL + Q Q + G +
Sbjct: 246 KIKS--------QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES--VK 295
Query: 413 QLMPQLSPTPSMMPSPNSHAAGFKGFGL-EGVPEKRLTDPGLSSLSALSTQVANLPNTVQ 471
+P S P P+P A G + P K P S L+ +A P TV+
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQP-----SGLTKPLAQQPGTVK 350
Query: 472 HMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQG 531
+ T K +P K + GS +P + P A + G
Sbjct: 351 PPVQPPGTT---KPPAQPLGPAKPPA--QQTGSEKPSSEQPGPKALAQPPGVG------- 398
Query: 532 ERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPL 591
K A + + P P L P + A +PG P+
Sbjct: 399 -----------------KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 592 SSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHAS 651
G K+ + G + TG + P SQ PA + PP G +
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPP------SQLPGPA--KPPPQQPGPAK----- 488
Query: 652 LPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKD 711
P P+ PG + G ++ + G + S PG T PS+ P
Sbjct: 489 -PPPQQPGSAKPPSQQPG--STKPPPQQPGPAKPSPQQPGSTK--PPSQQP--------- 534
Query: 712 SFGSAVPRNVSGFPQYPTGQEKG---DFTGHGERKGRNEKFPSLLQEVLQGYH------- 761
GSA P P P+ Q+ TG G+ PS Q QG
Sbjct: 535 --GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLC 592
Query: 762 -------HHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNE-LASRGLLNKSIGSLLE 813
H P++ + E Q SL G PN +++ E L + +++G
Sbjct: 593 NTTELLLHVPEKANFNTCTECQTTVCSLCG-FNPNPHLTEVKEWLCLNCQMKRALG---- 647
Query: 814 NPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPL 873
G SS P++K +T K +PQ ++ + + + S +
Sbjct: 648 ----GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP 703
Query: 874 RQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPG---------------GLVSME 918
+V+ P H A + P + +P +V
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763
Query: 919 TKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDY 978
T L S S + D SK Q+ K + P +K +S A P + +
Sbjct: 764 TDLVSSSSATTKPDIPSSKVQSQAEEKTT------PPLKTDS----AKPSQSFPPTGEKV 813
Query: 979 GPQDSRPTP-------MRRVPGRVGGREGMRGRSPSQYHDFAEK--LKMS--PGRSRGPG 1027
P DS+ P + PG +G + P Q + +K KMS P P
Sbjct: 814 SPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873
Query: 1028 GDPHHMNPHMTFSERANRSSLHTP-FSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYK 1086
G P P T + ++ TP SP + + + N G SQ
Sbjct: 874 GSPTPPGPRPTAGQ-----TVPTPQQSPKPQEQSRRFSLN-----LGSITDAPKSQPTTP 923
Query: 1087 RQMYQQQPEEYKDWSSGSAQGVIAAA----QHRQEGPRKSPRQQQFLDRVRSPLKNDKDG 1142
++ + + A +I+ A H Q GP +Q +P + +
Sbjct: 924 QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ--------APAPS-QPP 974
Query: 1143 MMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSG 1202
GPP T P A P K + +K +E+ + + P
Sbjct: 975 TSQGPPKSTGQAPPA-------------PAKSIPVK------KETKAPAAEKLEPKAEQA 1015
Query: 1203 PPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFIS 1262
P ++ PP D L Q + + + + P E S PL +
Sbjct: 1016 PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE---STCPLCK--------T 1064
Query: 1263 PIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQ---------------- 1306
+ + N+ TE K ++ + FN HL+ Q
Sbjct: 1065 ELNIGSKDPPNFNTCTECKNQVCNLC------GFNPTPHLTEIQEWLCLNCQTQRAISGQ 1118
Query: 1307 --DIKSIPKRDSSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNI 1364
DI+ +P S P + P T +S KT + P K + K +
Sbjct: 1119 LGDIRKMPPAPS-----GPKASPMPVPTESSSQKTAVPPQVK---------LVKKQEQEV 1164
Query: 1365 RRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQEL 1424
+ A E +T++++ I PP + D ++ + ++ D S L
Sbjct: 1165 KTEAEKVILEKVKETLSMEKI------PP------MVTTDQKQEESKLEKDKAS----AL 1208
Query: 1425 HVEKPLPRS-----SEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQK-----PGS 1474
+KPLP EE S + K E T K P A TS ++
Sbjct: 1209 QEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQ 1268
Query: 1475 NQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYF 1534
Q + G AP + K P P++ KE+D T + K++ PP
Sbjct: 1269 VQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAK 1328
Query: 1535 PSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSAD 1572
P + G+ +K+ + Q P+ P+G +D
Sbjct: 1329 PDQVEPGKE----KTEKEDDKSDTSSSQQPKSPQGLSD 1362
Score = 48.9 bits (115), Expect = 5e-05
Identities = 118/535 (22%), Positives = 187/535 (34%), Gaps = 97/535 (18%)
Query: 1198 AKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLR--LPGQEDHSSQNPLIMRR 1255
+KSS P +S K+ P + L++A + KP ++ + L G ++ P
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQD----LSKAPEPKKPPPLVKQPTLHGSPSAKAKQP----P 724
Query: 1256 RVRSFISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRD 1315
S P P K S S +DK + K K L S + P
Sbjct: 725 EADSLSKPAPPKEPSVP----SEQDKAPVA-DDKPKQPKMVKPTTDLVSSSSATTKPDIP 779
Query: 1316 SSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEA 1375
SSK + + P + S ++ PP + V S I R AS +
Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK-------VSPFDSKAIPRPASDSK--- 829
Query: 1376 GGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSE 1435
I+S E D +K + + A +SP KP+P+ S
Sbjct: 830 ---------IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA----KPMPKGSP 876
Query: 1436 EWRGSVDDKVKTETHAETVTAGKEPP-------------GAMTSTTSQKPGSNQGRPDGS 1482
G T +TV ++ P G++T +P + Q G
Sbjct: 877 TPPGP------RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
Query: 1483 LGGTAPLIFPDSKN-VPPVGILAP--EANPKAEEKENDTVTISPKQEGFPPK--GYFPSG 1537
L G IF + N + G P ++ P A K+ + P +G PPK G P
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG-PPKSTGQAPPA 989
Query: 1538 KKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRK 1597
K P+ K ++ P Q P + + +P P K + + A+P+
Sbjct: 990 PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIK-----DSKSLTAEPQ--- 1041
Query: 1598 TKQAVPIVEPQEPEIKLKYATQPLDKTDAK-NKSFYPYIHVVNKCELGAVCTIINAE--- 1653
K +P + P+ + +T PL KT+ P + +C+ VC +
Sbjct: 1042 -KAVLPTKLEKSPKPE---STCPLCKTELNIGSKDPPNFNTCTECK-NQVCNLCGFNPTP 1096
Query: 1654 --EEEQTKLVRGRKGQRSLT--------PPPSSTESKALPASSFMLQGPVVTESS 1698
E Q L + QR+++ PP+ + KA P PV TESS
Sbjct: 1097 HLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPM-------PVPTESS 1144
Score = 45.8 bits (107), Expect = 4e-04
Identities = 150/681 (22%), Positives = 216/681 (31%), Gaps = 86/681 (12%)
Query: 96 KDPVTT-GTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQ 154
K PV GT +PP + P GP + PP + + SE + AQ G+G Q
Sbjct: 350 KPPVQPPGTTKPPAQ-PLGPAK---PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405
Query: 155 DYTGPFSPGSAQYQQQASSQQQ---QQQVQQLRQQLYQSHQPLP-----QATGQPASSSS 206
GP P + Q QQ Q + QP P Q G +S+
Sbjct: 406 ---GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462
Query: 207 HLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSS-----SSSFPSPQRFSQSGQSYD 261
P + PS LP A + G Q S+ S+ P PQ+ + S
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522
Query: 262 GSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQ 321
+ SQ G S Q + + + + K Q +QP Q
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
Query: 322 QHPSQ--HVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQS 379
P + T +P ++ + + V S F NP+P + V+
Sbjct: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGF--------NPNPHLTEVKE 634
Query: 380 PSC----------------SSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTP- 422
C S+P P ++T S S + Q P+ P
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTT---SAVSKSSPQPQQTSPKKDAAPK 691
Query: 423 ---SMMPSPNSHAAGFKGFGLEGVPE-KRLTDPGLSSLSALST-QVANLPNTVQHMLLSD 477
S P P K L G P K P SLS + + ++P+ ++D
Sbjct: 692 QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD 751
Query: 478 ALTPQKKTSKRPSSSKKADSCT------NSEGSSQPEEQLKSPMAESLDGGCSSSSEDQG 531
Q K K + + S T +S+ SQ EE+ P+ S S G
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD-SAKPSQSFPPTG 810
Query: 532 ERVRQLSGQ------STSSDTTYKGGASEKAGSSPAQGAQN-EPPRLNASPAAREEATSP 584
E+V + S S ++ G +SE G Q E P+ A + + P
Sbjct: 811 EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK----KAQTKMSPKP 866
Query: 585 GAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGA 644
AK MP S P T G V + KP Q + + + T P S
Sbjct: 867 DAKPMPKGSP-TPPGPRPTAGQTVPTPQQS---PKPQEQSRRFSLNLGSITDAPKSQ--- 919
Query: 645 KETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGS 704
+ PQ G G SN HS +GPG + P+ S
Sbjct: 920 -----PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPP 974
Query: 705 LRYSYKDSFGSAVPRNVSGFP 725
S G A P P
Sbjct: 975 TSQGPPKSTGQAPPAPAKSIP 995
Score = 42.4 bits (98), Expect = 0.004
Identities = 85/377 (22%), Positives = 138/377 (36%), Gaps = 59/377 (15%)
Query: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560
G LAP + + + VT + P+ S KK P ++K + ++PPP
Sbjct: 648 GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707
Query: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVE--PQEPEIKLKYAT 1618
QP GS + K + + P +P + P+ + P++P++ +K T
Sbjct: 708 KQPTL--HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM-VKPTT 764
Query: 1619 QPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPP---- 1674
+ + A K P V ++ EE+ T ++ + S + PP
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQA------------EEKTTPPLKTDSAKPSQSFPPTGEK 812
Query: 1675 -SSTESKALP---ASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYA 1730
S +SKA+P + S ++ P + S V + K + + P+ A
Sbjct: 813 VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKM----SPKPDA 868
Query: 1731 ATLPK---NPPPKRATEMQS----------KVKVRHKSASNGSKTDTEEEEEQQQQQKEQ 1777
+PK PP R T Q+ + + R S + GS TD + + Q+
Sbjct: 869 KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928
Query: 1778 RSLAAHPR--FKRRHRSEDCGG--GPRSLS-RGLPCKKAATEGSSEKTVLDSKPSVPTTS 1832
L F + G GP S S G P K+A PS P TS
Sbjct: 929 GKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA------------PSQPPTS 976
Query: 1833 EGGPELELQIPELPLDS 1849
+G P+ Q P P S
Sbjct: 977 QGPPKSTGQAPPAPAKS 993
Score = 35.0 bits (79), Expect = 0.71
Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 15/170 (8%)
Query: 438 FGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTP-----QKKTSKRPSSS 492
FGL K +TD S+L T + L NT++ L +A P + + S RPSS
Sbjct: 4243 FGLR----KNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSV 4298
Query: 493 KKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLS-GQSTSSDTTYKGG 551
D + SS +LK+ AE+LD S +S + L QS
Sbjct: 4299 YGLDLSIKRDSSSS-SLRLKAQEAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQN 4357
Query: 552 ASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNE 601
+ E++ SP +P + + A S +D SS P+V +
Sbjct: 4358 SEEESPLSPV----GQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQ 4403
Score = 33.5 bits (75), Expect = 2.1
Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 10/76 (13%)
Query: 1530 PKGYFPSGKK-------KGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQ 1582
P PSG K RP + QPPPPPP PP P P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP---PPPPPPPPPPLP 2428
Query: 1583 RRERRKPGAQPRKRKT 1598
KP P+K+ T
Sbjct: 2429 PPTSPKPTILPKKKLT 2444
Score = 33.1 bits (74), Expect = 2.7
Identities = 148/729 (20%), Positives = 217/729 (29%), Gaps = 159/729 (21%)
Query: 1197 PAKSSG---PPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVML-----RLPGQEDH-SS 1247
P K SG PG +Q TD + P ++ L R +E+H SS
Sbjct: 92 PPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSS 151
Query: 1248 QNP-LIMRRRVRSFISPIPSKRQSQDV---KNSSTEDKGRLLHSSKEGADKAFNSYAHLS 1303
P + S +S + +K D+ +S E+ + ++ K
Sbjct: 152 MMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL 211
Query: 1304 HSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPN 1363
Q K IPK+ P +++ P K K PP G G ++ Q + +
Sbjct: 212 QQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP--GTGKPIQGPTQTPQTDH 269
Query: 1364 ----IRRSASSNSAEAGGDTVTLDDILSLKSGP-------PEGGSVAVQDADIEKRKGEV 1412
++R AS + D V + + P P G Q EK +
Sbjct: 270 AKLPLQRDASRPQTKQA-DIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328
Query: 1413 ASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEP------------ 1460
A P+ + KPL + + V T+ A+ + K P
Sbjct: 329 AKPPAQPSG----LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384
Query: 1461 ---------PGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVP------------- 1498
P + T +Q+PG + P +G PL P
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKP-PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443
Query: 1499 --PVGILAPEANPKAEEKENDTVTISPKQ-------------EGFPPKGYFPSGKKKGRP 1543
P I A +A P + T P Q PP S K +
Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503
Query: 1544 IGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQA-- 1601
GS +Q P P PQ P + + K Q+ KP AQ + Q
Sbjct: 504 PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563
Query: 1602 -----VPIVEP---QEPEIKLKYATQPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAE 1653
P V P Q P L PL T +HV K CT
Sbjct: 564 GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL------LLHVPEKANFN-TCT----- 611
Query: 1654 EEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQGPVVTESSVMGHLVCCLCGKWAS 1713
E QT + P P TE K LC
Sbjct: 612 -ECQTTVC----SLCGFNPNPHLTEVKE------------------------WLCLNCQM 642
Query: 1714 YRNMGDLFGPFYPQDYAATLPKNPPPKRATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQ 1773
R +G P +P +P PK T + KS+ +T +++ +Q
Sbjct: 643 KRALGGDLAP---------VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 1774 QK------------EQRSLAAHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEGSSEKT- 1820
+Q +L P K + E SLS+ P K+ + +K
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE-----ADSLSKPAPPKEPSVPSEQDKAP 748
Query: 1821 VLDSKPSVP 1829
V D KP P
Sbjct: 749 VADDKPKQP 757
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 63.5 bits (153), Expect = 2e-09
Identities = 298/1478 (20%), Positives = 478/1478 (32%), Gaps = 288/1478 (19%)
Query: 184 RQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSS 243
+Q+L SH P + +G+P QP S + Q G+ S+ S
Sbjct: 84 KQELDSSHPP--KQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRS----PSTISLKE 137
Query: 244 SSSFPSPQRFSQSGQSYDGSYNVNAGS-------QYEGHNVGSNAQAYGTQSNYSYQPQS 296
S S + +S VNA S ++ ++ S+++A ++ + Q
Sbjct: 138 SKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETT---KKQK 194
Query: 297 MKNFEQAKIPQGTQQGQQQQQPQQ----QQHPSQHVMQYTNAATKLPLQSQVGQYNQPEV 352
+ EQ K P+G + QQQP + QQ P + +Q + Q QPE
Sbjct: 195 VVQKEQGK-PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQ-------QPE- 245
Query: 353 PVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRIL 412
++S P P Q+P PL + Q Q + G +
Sbjct: 246 KIKS--------QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES--VK 295
Query: 413 QLMPQLSPTPSMMPSPNSHAAGFKGFGL-EGVPEKRLTDPGLSSLSALSTQVANLPNTVQ 471
+P S P P+P A G + P K P S L+ +A P TV+
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQP-----SGLTKPLAQQPGTVK 350
Query: 472 HMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQG 531
+ T K +P K + GS +P + P A + G
Sbjct: 351 PPVQPPGTT---KPPAQPLGPAKPPA--QQTGSEKPSSEQPGPKALAQPPGVG------- 398
Query: 532 ERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPL 591
K A + + P P L P + A +PG P+
Sbjct: 399 -----------------KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 592 SSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHAS 651
G K+ + G + TG + P SQ PA + PP G +
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPP------SQLPGPA--KPPPQQPGPAK----- 488
Query: 652 LPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKD 711
P P+ PG + G ++ + G + S PG T PS+ P
Sbjct: 489 -PPPQQPGSAKPPSQQPG--STKPPPQQPGPAKPSPQQPGSTK--PPSQQP--------- 534
Query: 712 SFGSAVPRNVSGFPQYPTGQEKG---DFTGHGERKGRNEKFPSLLQEVLQGYH------- 761
GSA P P P+ Q+ TG G+ PS Q QG
Sbjct: 535 --GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLC 592
Query: 762 -------HHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNE-LASRGLLNKSIGSLLE 813
H P++ + E Q SL G PN +++ E L + +++G
Sbjct: 593 NTTELLLHVPEKANFNTCTECQTTVCSLCG-FNPNPHLTEVKEWLCLNCQMKRALG---- 647
Query: 814 NPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPL 873
G SS P++K +T K +PQ ++ + + + S +
Sbjct: 648 ----GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP 703
Query: 874 RQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPG---------------GLVSME 918
+V+ P H A + P + +P +V
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763
Query: 919 TKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDY 978
T L S S + D SK Q+ K + P +K +S A P + +
Sbjct: 764 TDLVSSSSATTKPDIPSSKVQSQAEEKTT------PPLKTDS----AKPSQSFPPTGEKV 813
Query: 979 GPQDSRPTP-------MRRVPGRVGGREGMRGRSPSQYHDFAEK--LKMS--PGRSRGPG 1027
P DS+ P + PG +G + P Q + +K KMS P P
Sbjct: 814 SPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873
Query: 1028 GDPHHMNPHMTFSERANRSSLHTP-FSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYK 1086
G P P T + ++ TP SP + + + N G SQ
Sbjct: 874 GSPTPPGPRPTAGQ-----TVPTPQQSPKPQEQSRRFSLN-----LGSITDAPKSQPTTP 923
Query: 1087 RQMYQQQPEEYKDWSSGSAQGVIAAA----QHRQEGPRKSPRQQQFLDRVRSPLKNDKDG 1142
++ + + A +I+ A H Q GP +Q +P + +
Sbjct: 924 QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ--------APAPS-QPP 974
Query: 1143 MMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSG 1202
GPP T P A P K + +K +E+ + + P
Sbjct: 975 TSQGPPKSTGQAPPA-------------PAKSIPVK------KETKAPAAEKLEPKAEQA 1015
Query: 1203 PPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFIS 1262
P ++ PP D L Q + + + + P E S PL +
Sbjct: 1016 PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE---STCPLCK--------T 1064
Query: 1263 PIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQ---------------- 1306
+ + N+ TE K ++ + FN HL+ Q
Sbjct: 1065 ELNIGSKDPPNFNTCTECKNQVCNLC------GFNPTPHLTEIQEWLCLNCQTQRAISGQ 1118
Query: 1307 --DIKSIPKRDSSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNI 1364
DI+ +P S P + P T +S KT + P K + K +
Sbjct: 1119 LGDIRKMPPAPS-----GPKASPMPVPTESSSQKTAVPPQVK---------LVKKQEQEV 1164
Query: 1365 RRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQEL 1424
+ A E +T++++ I PP + D ++ + ++ D S L
Sbjct: 1165 KTEAEKVILEKVKETLSMEKI------PP------MVTTDQKQEESKLEKDKAS----AL 1208
Query: 1425 HVEKPLPRS-----SEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQK-----PGS 1474
+KPLP EE S + K E T K P A TS ++
Sbjct: 1209 QEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQ 1268
Query: 1475 NQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYF 1534
Q + G AP + K P P++ KE+D T + K++ PP
Sbjct: 1269 VQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAK 1328
Query: 1535 PSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSAD 1572
P + G+ +K+ + Q P+ P+G +D
Sbjct: 1329 PDQVEPGKE----KTEKEDDKSDTSSSQQPKSPQGLSD 1362
Score = 48.9 bits (115), Expect = 5e-05
Identities = 118/535 (22%), Positives = 187/535 (34%), Gaps = 97/535 (18%)
Query: 1198 AKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLR--LPGQEDHSSQNPLIMRR 1255
+KSS P +S K+ P + L++A + KP ++ + L G ++ P
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQD----LSKAPEPKKPPPLVKQPTLHGSPSAKAKQP----P 724
Query: 1256 RVRSFISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRD 1315
S P P K S S +DK + K K L S + P
Sbjct: 725 EADSLSKPAPPKEPSVP----SEQDKAPVA-DDKPKQPKMVKPTTDLVSSSSATTKPDIP 779
Query: 1316 SSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEA 1375
SSK + + P + S ++ PP + V S I R AS +
Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK-------VSPFDSKAIPRPASDSK--- 829
Query: 1376 GGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSE 1435
I+S E D +K + + A +SP KP+P+ S
Sbjct: 830 ---------IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA----KPMPKGSP 876
Query: 1436 EWRGSVDDKVKTETHAETVTAGKEPP-------------GAMTSTTSQKPGSNQGRPDGS 1482
G T +TV ++ P G++T +P + Q G
Sbjct: 877 TPPGP------RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
Query: 1483 LGGTAPLIFPDSKN-VPPVGILAP--EANPKAEEKENDTVTISPKQEGFPPK--GYFPSG 1537
L G IF + N + G P ++ P A K+ + P +G PPK G P
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG-PPKSTGQAPPA 989
Query: 1538 KKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRK 1597
K P+ K ++ P Q P + + +P P K + + A+P+
Sbjct: 990 PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIK-----DSKSLTAEPQ--- 1041
Query: 1598 TKQAVPIVEPQEPEIKLKYATQPLDKTDAK-NKSFYPYIHVVNKCELGAVCTIINAE--- 1653
K +P + P+ + +T PL KT+ P + +C+ VC +
Sbjct: 1042 -KAVLPTKLEKSPKPE---STCPLCKTELNIGSKDPPNFNTCTECK-NQVCNLCGFNPTP 1096
Query: 1654 --EEEQTKLVRGRKGQRSLT--------PPPSSTESKALPASSFMLQGPVVTESS 1698
E Q L + QR+++ PP+ + KA P PV TESS
Sbjct: 1097 HLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPM-------PVPTESS 1144
Score = 45.8 bits (107), Expect = 4e-04
Identities = 150/681 (22%), Positives = 216/681 (31%), Gaps = 86/681 (12%)
Query: 96 KDPVTT-GTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQ 154
K PV GT +PP + P GP + PP + + SE + AQ G+G Q
Sbjct: 350 KPPVQPPGTTKPPAQ-PLGPAK---PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405
Query: 155 DYTGPFSPGSAQYQQQASSQQQ---QQQVQQLRQQLYQSHQPLP-----QATGQPASSSS 206
GP P + Q QQ Q + QP P Q G +S+
Sbjct: 406 ---GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462
Query: 207 HLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSS-----SSSFPSPQRFSQSGQSYD 261
P + PS LP A + G Q S+ S+ P PQ+ + S
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522
Query: 262 GSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQ 321
+ SQ G S Q + + + + K Q +QP Q
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
Query: 322 QHPSQ--HVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQS 379
P + T +P ++ + + V S F NP+P + V+
Sbjct: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGF--------NPNPHLTEVKE 634
Query: 380 PSC----------------SSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTP- 422
C S+P P ++T S S + Q P+ P
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTT---SAVSKSSPQPQQTSPKKDAAPK 691
Query: 423 ---SMMPSPNSHAAGFKGFGLEGVPE-KRLTDPGLSSLSALST-QVANLPNTVQHMLLSD 477
S P P K L G P K P SLS + + ++P+ ++D
Sbjct: 692 QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD 751
Query: 478 ALTPQKKTSKRPSSSKKADSCT------NSEGSSQPEEQLKSPMAESLDGGCSSSSEDQG 531
Q K K + + S T +S+ SQ EE+ P+ S S G
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD-SAKPSQSFPPTG 810
Query: 532 ERVRQLSGQ------STSSDTTYKGGASEKAGSSPAQGAQN-EPPRLNASPAAREEATSP 584
E+V + S S ++ G +SE G Q E P+ A + + P
Sbjct: 811 EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK----KAQTKMSPKP 866
Query: 585 GAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGA 644
AK MP S P T G V + KP Q + + + T P S
Sbjct: 867 DAKPMPKGSP-TPPGPRPTAGQTVPTPQQS---PKPQEQSRRFSLNLGSITDAPKSQ--- 919
Query: 645 KETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGS 704
+ PQ G G SN HS +GPG + P+ S
Sbjct: 920 -----PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPP 974
Query: 705 LRYSYKDSFGSAVPRNVSGFP 725
S G A P P
Sbjct: 975 TSQGPPKSTGQAPPAPAKSIP 995
Score = 42.4 bits (98), Expect = 0.004
Identities = 85/377 (22%), Positives = 138/377 (36%), Gaps = 59/377 (15%)
Query: 1501 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1560
G LAP + + + VT + P+ S KK P ++K + ++PPP
Sbjct: 648 GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707
Query: 1561 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVE--PQEPEIKLKYAT 1618
QP GS + K + + P +P + P+ + P++P++ +K T
Sbjct: 708 KQPTL--HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM-VKPTT 764
Query: 1619 QPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPP---- 1674
+ + A K P V ++ EE+ T ++ + S + PP
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQA------------EEKTTPPLKTDSAKPSQSFPPTGEK 812
Query: 1675 -SSTESKALP---ASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYA 1730
S +SKA+P + S ++ P + S V + K + + P+ A
Sbjct: 813 VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKM----SPKPDA 868
Query: 1731 ATLPK---NPPPKRATEMQS----------KVKVRHKSASNGSKTDTEEEEEQQQQQKEQ 1777
+PK PP R T Q+ + + R S + GS TD + + Q+
Sbjct: 869 KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928
Query: 1778 RSLAAHPR--FKRRHRSEDCGG--GPRSLS-RGLPCKKAATEGSSEKTVLDSKPSVPTTS 1832
L F + G GP S S G P K+A PS P TS
Sbjct: 929 GKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA------------PSQPPTS 976
Query: 1833 EGGPELELQIPELPLDS 1849
+G P+ Q P P S
Sbjct: 977 QGPPKSTGQAPPAPAKS 993
Score = 35.0 bits (79), Expect = 0.71
Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 15/170 (8%)
Query: 438 FGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTP-----QKKTSKRPSSS 492
FGL K +TD S+L T + L NT++ L +A P + + S RPSS
Sbjct: 4243 FGLR----KNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSV 4298
Query: 493 KKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLS-GQSTSSDTTYKGG 551
D + SS +LK+ AE+LD S +S + L QS
Sbjct: 4299 YGLDLSIKRDSSSS-SLRLKAQEAEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQN 4357
Query: 552 ASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNE 601
+ E++ SP +P + + A S +D SS P+V +
Sbjct: 4358 SEEESPLSPV----GQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQ 4403
Score = 33.5 bits (75), Expect = 2.1
Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 10/76 (13%)
Query: 1530 PKGYFPSGKK-------KGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQ 1582
P PSG K RP + QPPPPPP PP P P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP---PPPPPPPPPPLP 2428
Query: 1583 RRERRKPGAQPRKRKT 1598
KP P+K+ T
Sbjct: 2429 PPTSPKPTILPKKKLT 2444
Score = 33.1 bits (74), Expect = 2.7
Identities = 148/729 (20%), Positives = 217/729 (29%), Gaps = 159/729 (21%)
Query: 1197 PAKSSG---PPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVML-----RLPGQEDH-SS 1247
P K SG PG +Q TD + P ++ L R +E+H SS
Sbjct: 92 PPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSS 151
Query: 1248 QNP-LIMRRRVRSFISPIPSKRQSQDV---KNSSTEDKGRLLHSSKEGADKAFNSYAHLS 1303
P + S +S + +K D+ +S E+ + ++ K
Sbjct: 152 MMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL 211
Query: 1304 HSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPN 1363
Q K IPK+ P +++ P K K PP G G ++ Q + +
Sbjct: 212 QQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP--GTGKPIQGPTQTPQTDH 269
Query: 1364 ----IRRSASSNSAEAGGDTVTLDDILSLKSGP-------PEGGSVAVQDADIEKRKGEV 1412
++R AS + D V + + P P G Q EK +
Sbjct: 270 AKLPLQRDASRPQTKQA-DIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328
Query: 1413 ASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEP------------ 1460
A P+ + KPL + + V T+ A+ + K P
Sbjct: 329 AKPPAQPSG----LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384
Query: 1461 ---------PGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVP------------- 1498
P + T +Q+PG + P +G PL P
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKP-PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443
Query: 1499 --PVGILAPEANPKAEEKENDTVTISPKQ-------------EGFPPKGYFPSGKKKGRP 1543
P I A +A P + T P Q PP S K +
Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503
Query: 1544 IGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQA-- 1601
GS +Q P P PQ P + + K Q+ KP AQ + Q
Sbjct: 504 PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563
Query: 1602 -----VPIVEP---QEPEIKLKYATQPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAE 1653
P V P Q P L PL T +HV K CT
Sbjct: 564 GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL------LLHVPEKANFN-TCT----- 611
Query: 1654 EEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQGPVVTESSVMGHLVCCLCGKWAS 1713
E QT + P P TE K LC
Sbjct: 612 -ECQTTVC----SLCGFNPNPHLTEVKE------------------------WLCLNCQM 642
Query: 1714 YRNMGDLFGPFYPQDYAATLPKNPPPKRATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQ 1773
R +G P +P +P PK T + KS+ +T +++ +Q
Sbjct: 643 KRALGGDLAP---------VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 1774 QK------------EQRSLAAHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEGSSEKT- 1820
+Q +L P K + E SLS+ P K+ + +K
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE-----ADSLSKPAPPKEPSVPSEQDKAP 748
Query: 1821 VLDSKPSVP 1829
V D KP P
Sbjct: 749 VADDKPKQP 757
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 63.2 bits (152), Expect = 2e-09
Identities = 282/1363 (20%), Positives = 444/1363 (32%), Gaps = 253/1363 (18%)
Query: 189 QSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASS------- 241
+SH PQ G+ SSS + S + +++ + S SS
Sbjct: 712 RSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS 771
Query: 242 ------SSSSSFPSPQRFSQSG--QSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQ 293
S S S P P++ SQ+ +S GS A S+ S++ Q + +
Sbjct: 772 RLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS 831
Query: 294 PQSMKNFE-QAKIPQGTQQGQ--------QQQQPQQQQHPSQHVMQYTNAATKLPLQSQV 344
QS + K+ GT Q +Q Q+ ++ P +
Sbjct: 832 RQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSC 891
Query: 345 GQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSP-----SCSSTPSPLMQTGENLQCG 399
+ P V +P + Q+ S S+P P + SP S SS+PSP T
Sbjct: 892 SGSSPPRVKSSTPPR--QSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR 949
Query: 400 QGSVPMGSR--NRIL-----------------QLMPQLSPTPSMMPSPNSHAAGFKGFGL 440
SV S +R+L + P+ S + S+ P P A G L
Sbjct: 950 SRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSL 1009
Query: 441 EGVPE-------------------------KRLTDPGLSSLSALSTQVANLPNTVQHMLL 475
G K T PG S S Q+ T
Sbjct: 1010 SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHR- 1068
Query: 476 SDALTPQKKTSKRPSSSKKADSCTNSEG----SSQPEEQL--KSPMAESLDGGCSSSSED 529
SD +P+ + S S S ++ S T+ +G SS P +L +SP+ + +S
Sbjct: 1069 SDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128
Query: 530 QGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNE-----PPR--LNASPAAREEAT 582
G Q QS SS S G S + A+++ PP+ ASP +++
Sbjct: 1129 SGMSPEQSRFQSDSSSYPTVDSNS-LLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187
Query: 583 SP-GAKDMPLSS-----------------DGNPKVNEKTVGVIVSRE-----AMTGRVEK 619
SP +D P SS +P+ E+ + S + + + E+
Sbjct: 1188 SPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEE 1247
Query: 620 PGGQ------------DKGSQEDDPAATQRPPSNGGAKET-SHASLPQPEPPGGGGSKGN 666
P GQ + E P +RP + ++ S ASL E P S G
Sbjct: 1248 PAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGG 1307
Query: 667 KNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSG--- 723
+ + H N ++ G R G L F S V +++G
Sbjct: 1308 PHF--SPEHKELSNSPLRENSFGSPLEFRNS-----GPLGTEMNTGFSSEVKEDLNGPFL 1360
Query: 724 -----FPQYPTGQEKGDFTGHG---------ERKGRNEKFPSLLQEVLQGYHHHPDRRYS 769
P ++ +GH E+ G + S+ VL P R S
Sbjct: 1361 NQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSN-QSISSPVLDAVPRTPSRERS 1419
Query: 770 RSTQEHQGMAGSLEGTTRPNVLVSQT-----NELASRGLLNKSIGSLLENPHWGPWERKS 824
S + G +R + S + SR L+ S + + P R
Sbjct: 1420 SSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE 1479
Query: 825 SSTAPEMKQINLTDYPIPR-----KFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRD 879
++PE K + T P R + + + E GS S +PL Q R
Sbjct: 1480 CDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRS 1539
Query: 880 PGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLK--SQSGQIKEEDFEQSK 937
+ L + + R S+S P T L+ S+SG E D SK
Sbjct: 1540 GSSQELDVKPSASPQER--------SESDSSPDSKAKTRTPLRQRSRSGSSPEVD---SK 1588
Query: 938 SQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGG 997
S+ S +SG P +K + A+P A S SD P+ P P R +P R
Sbjct: 1589 SRLSPRRSRSGSS---PEVKDKP---RAAPRA---QSGSDSSPEPKAPAP-RALPRRSRS 1638
Query: 998 REGMRGRSPS-QYHDFAEKLKMSPGRSR----GPGGDPH--------------HMNPHMT 1038
+GR PS + E P +SR G P +P +T
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698
Query: 1039 FSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYK 1098
R +R S SP + + H R+ + P S+ +R+
Sbjct: 1699 RKARLSRRSRSASSSPETRSRTPPRHR--RSPSVSSPEPAEKSRSSRRRR---------- 1746
Query: 1099 DWSSGSAQGVIAAAQHRQEGPR----KSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHD 1154
S+ S + + + R P+ + R + ++ R+ + D+ G
Sbjct: 1747 --SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804
Query: 1155 PSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGP 1214
S R G ++ S QES SR+ +S PP + R
Sbjct: 1805 RSRSRVTRRRRGGSGYHSR-------SPARQESSRTSSRRRR-GRSRTPPTSRKRSR--- 1853
Query: 1215 PHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVK 1274
T + + P + S+ PLI RRR RS SP+ +R
Sbjct: 1854 -SRTSPAPWKRSRSRASPAT-------HRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTS 1905
Query: 1275 NSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLP----SPDSRNCPA 1330
+ + R S+ + + +R S+ P SR P
Sbjct: 1906 VTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV 1965
Query: 1331 VTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSA 1373
S ++T + R+ R TSP RR + S ++
Sbjct: 1966 TRRRSRSRTSPITRRRSRSR---------TSPVTRRRSRSRTS 1999
Score = 59.3 bits (142), Expect = 4e-08
Identities = 231/1117 (20%), Positives = 376/1117 (33%), Gaps = 137/1117 (12%)
Query: 482 QKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQS 541
+ +TS+R S S + S SS+ L SP S ++ + R LSG S
Sbjct: 733 KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP---------RSKAKSRLSLRRSLSGSS 783
Query: 542 -TSSDTTYKGGASEKAGSSPAQGAQNEPP---RLNASPAAREEATSPGAKDMPLSSDGNP 597
+ ++GSS + PP R ++SP ++++ +P ++ SS +P
Sbjct: 784 PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP-SRQSHSSSSPHP 842
Query: 598 KVNEKT---VGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQ 654
KV T G I S +A V P + DP R PS +S +
Sbjct: 843 KVKSGTPPRQGSITSPQANEQSV-TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKS 901
Query: 655 PEPPGGGGSKGNKNGDN-NSNHNGEGNGQSGHSAAGPG-FTSRTEP----SKSPGS---- 704
PP S+ + + + SG S+ P TSRT P S SP S
Sbjct: 902 STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVES 961
Query: 705 ---LRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYH 761
RYS+ GS+ P P G + + + K + PSL
Sbjct: 962 RLLPRYSHS---GSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQ 1018
Query: 762 HHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWE 821
+S + ++ +T P + L +G S +
Sbjct: 1019 EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP------------D 1066
Query: 822 RKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPG 881
+S +++PE++Q + + K + P+ ++E + SP+RQ D G
Sbjct: 1067 HRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTE----LASRSPIRQ---DRG 1119
Query: 882 AHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQAS 941
S M R S + + +++L++ + K Q + AS
Sbjct: 1120 EFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATAS 1179
Query: 942 FNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGM 1001
PP K + SP S +D+ TP R G E
Sbjct: 1180 -----------PPRQKDK-----FSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETK 1223
Query: 1002 RGRSPSQYHDFAEKLKMSPGRSRGPGGD-PHHMNPHMTFSERAN-RSSLHTPFSP----- 1054
S E+L +S P G H++ + +N SS P
Sbjct: 1224 EQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLT 1283
Query: 1055 ----NSETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIA 1110
S+ A + A ++G P H+ + + ++ S GS
Sbjct: 1284 LDQSQSQASLEAVEVPSMASSWGGP--------HFSPEHKELSNSPLRENSFGS------ 1329
Query: 1111 AAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCL--MSSD 1168
+ R GP + F V+ L + P + S + +G +S D
Sbjct: 1330 PLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPD 1389
Query: 1169 GLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPP-------HETDGH 1221
+ GM +Q + D +T P++ S + + G P
Sbjct: 1390 AVEKAGMS---SNQSISSPVLDAVPRT-PSRERSSSASSPEMKDGLPRTPSRRSRSGSSP 1445
Query: 1222 GLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISP--IPSKRQSQDVKNSSTE 1279
GL + + + S+ PG +D + P R S P +P + + SS E
Sbjct: 1446 GLRDGSGTPSRHSLSGSSPGMKD-IPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504
Query: 1280 DKGRLLHSSKE--GADKAFN--SYAHLSHSQDIKSIPKRD-SSKDLPSPDSRNCPAVTLT 1334
+ L +E G++ + + + A Q +S ++ K SP R+ +
Sbjct: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPD 1564
Query: 1335 SPAKTKI-LPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTVTLDDILSLKSGPP 1393
S AKT+ L R G E + SP RRS S +S E S P
Sbjct: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSP--RRSRSGSSPEVKDKPRAAPRAQSGSDSSP 1622
Query: 1394 EGGSVAVQDADIEKRKGEVASDL-VSP---ANQELHVEKPLPRSSEEWRGSVDDKVKTET 1449
E + A + R G + SP ++ E E P P+S RGS +
Sbjct: 1623 EPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP-PKSRTARRGS-------RS 1674
Query: 1450 HAETVTAGKEPPGAMTSTTSQKPG-----SNQGRPDGSLGGTAPLIFPDSKNVPPVGILA 1504
E T + PP +S +S + S + R S T P + P V +
Sbjct: 1675 SPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS--S 1732
Query: 1505 PEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKG 1541
PE K+ SP+ + +G PS K +G
Sbjct: 1733 PEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRG 1769
Score = 57.4 bits (137), Expect = 1e-07
Identities = 223/1166 (19%), Positives = 391/1166 (33%), Gaps = 161/1166 (13%)
Query: 476 SDALTPQKKTSKRPSSSKKADSCTN---SEGSSQPE---EQLKSPMAESLDGGCSSSSED 529
S + TPQ++ SS +K S T+ S +S PE ++ S + SL S +
Sbjct: 713 SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
Query: 530 QGERVRQLSGQSTS-SDTTYKGGASEKAGSSPAQGAQNEPPRLN---ASPAAREEATSPG 585
R R LSG S + ++GSS + PPR + +SP ++++ +P
Sbjct: 773 LSLR-RSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP- 830
Query: 586 AKDMPLSSDGNPKVNEKTV---GVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNG 642
++ SS +PKV T G I S +A V P + DP R PS
Sbjct: 831 SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVT-PQRRSCFESSPDPELKSRTPSRH 889
Query: 643 GAKETSHASLPQPEPPGGGGSKGNKNGDN-NSNHNGEGNGQSGHSAAGPG-FTSRTEP-- 698
+S + PP S+ + + + SG S+ P TSRT P
Sbjct: 890 SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR 949
Query: 699 --SKSPGSL-------RYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKF 749
S SP S RYS+ GS+ P P G + + + K +
Sbjct: 950 SRSVSPCSNVESRLLPRYSHS---GSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPG 1006
Query: 750 PSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASRGLLNKSIG 809
PSL +S + ++ +T P + L +G S
Sbjct: 1007 PSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP- 1065
Query: 810 SLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSAHEPGGSLSERRSVICD 869
+ +S +++PE++Q + + K + P+ ++E +
Sbjct: 1066 -----------DHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTE----LAS 1110
Query: 870 ISPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIK 929
SP+RQ D G S M R S + + +++L++ + K
Sbjct: 1111 RSPIRQ---DRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEK 1167
Query: 930 EEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMR 989
Q + AS PP K + SP S +D+ TP R
Sbjct: 1168 MALPPQEDATAS-----------PPRQKDKF-----SPFPVQDRPESSLVFKDTLRTPPR 1211
Query: 990 RVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDP-HHMNPHMTFSERAN-RSS 1047
G E S E+L +S P G H++ + +N SS
Sbjct: 1212 ERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESS 1271
Query: 1048 LHTPFSP---------NSETLASAYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYK 1098
P S+ A + A ++G P H+ + + +
Sbjct: 1272 PEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGP--------HFSPEHKELSNSPLR 1323
Query: 1099 DWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQ 1158
+ S GS + R GP + F V+ L + P + S +
Sbjct: 1324 ENSFGSP------LEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTR 1377
Query: 1159 EAGRCL--MSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPH 1216
+G +S D + GM +Q + D +T P++ S + + G P
Sbjct: 1378 SSGHSSSELSPDAVEKAGMS---SNQSISSPVLDAVPRT-PSRERSSSASSPEMKDGLPR 1433
Query: 1217 ETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVKNS 1276
+ ++ + GS P + S +P + IP
Sbjct: 1434 TPSRRSRSGSSPGLRDGS---GTPSRHSLSGSSP---------GMKDIPR---------- 1471
Query: 1277 STEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTSP 1336
T +GR + S + K++P+ P P SR+ + L +
Sbjct: 1472 -TPSRGR----------------SECDSSPEPKALPQT------PRPRSRSPSSPELNN- 1507
Query: 1337 AKTKILPPRKGRGLKLEAIVQKITS--PNIRRSASSNSAEAGGDTVTLDDILSLKSGPPE 1394
K L P++ R ++ QK + P +RS S +S E S P+
Sbjct: 1508 ---KCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPD 1564
Query: 1395 GGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETV 1454
S A + +R +S V + L + SS E + + ++ +++
Sbjct: 1565 --SKAKTRTPLRQRSRSGSSPEVD-SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSS 1621
Query: 1455 TAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEK 1514
K P S+ S++GR G ++ P+ PP A + + E
Sbjct: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH---PPKSRTARRGSRSSPEP 1678
Query: 1515 ENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGE 1574
+ + T ++ + R + + + + + PP + P +
Sbjct: 1679 KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV------SS 1732
Query: 1575 PKPKKQRQRRERRKPGAQPRKRKTKQ 1600
P+P ++ + RR+ + PR + T +
Sbjct: 1733 PEPAEKSRSSRRRRSASSPRTKTTSR 1758
Score = 46.2 bits (108), Expect = 3e-04
Identities = 67/308 (21%), Positives = 107/308 (34%), Gaps = 61/308 (19%)
Query: 1549 KQKKQQQPPPPPPQPPQ-IPEGSADGEPKPKKQRQR----RERRKPGAQPRKRKTKQAVP 1603
+ ++ +QP P PP+P + E S+ P PK+++++ R RR + PR+ + K +
Sbjct: 156 RAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK 215
Query: 1604 IVEPQEPEIKLKYATQPLDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRG 1663
E E K + P K+ K+K +
Sbjct: 216 KKHRSESESKKRKHRSPTPKSKRKSKD-------------------------------KK 244
Query: 1664 RKGQRSLTPPPSST---ESKALPASSFMLQGPVVTESSVMGHLVCCLCGKWAS----YRN 1716
RK RS TP P S S + ++S + S+ L G+ S R
Sbjct: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
Query: 1717 MGDLFGPFYPQDYAATLPKNPPPKRATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKE 1776
GD PF +T + P + S + + K S T E+ E
Sbjct: 305 EGD--APFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPE 362
Query: 1777 QRSLAAHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGP 1836
A P RH GG P+ L AT S++ V + PT P
Sbjct: 363 PP--APTPLLAERH-----GGSPQPL---------ATTPLSQEPVNPPSEASPTRDRSPP 406
Query: 1837 ELELQIPE 1844
+ ++P+
Sbjct: 407 KSPEKLPQ 414
Score = 46.2 bits (108), Expect = 3e-04
Identities = 86/421 (20%), Positives = 150/421 (35%), Gaps = 72/421 (17%)
Query: 1191 LSRQTSP-----AKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDH 1245
+S +TSP A+S PP SQ R T + +++ + S L P Q+
Sbjct: 2393 VSGRTSPPLLDRARSRTPPSAPSQSRM-----TSERAPSPSSRMGQAPSQSLLPPAQDQP 2447
Query: 1246 SSQNPLIMRRRVRSFISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHS 1305
S P + R I+ Q+ V S + G + ++ D
Sbjct: 2448 RSPVPSAFSDQSRCLIA------QTTPVAGSQSLSSGAVATTTSSAGDH----------- 2490
Query: 1306 QDIKSIPKRDSSKDLPSPDSRNCPAVT-LTSPAKTKILPPRKGRGLKLEAIVQKITSPNI 1364
+ S+P + +P D PA T P+ L P K R + + +S +
Sbjct: 2491 NGMLSVP----APGVPHSDVGEPPASTGAQQPSALAALQPAKER--RSSSSSSSSSSSSS 2544
Query: 1365 RRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQEL 1424
S+SS+S+ + G + S EG S+ VQ KR V S +P
Sbjct: 2545 SSSSSSSSSSSSGSS----------SSDSEGSSLPVQPEVALKR---VPSPTPAPKEAVR 2591
Query: 1425 HVEKPLPRSSEEWR---GSVDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDG 1481
P P ++ R S + + + + ++ + +S++S S+ P
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
Query: 1482 SLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKG 1541
+ G L P S PP G + K + D+ ++S Y P
Sbjct: 2652 AKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLS----------YSP------ 2695
Query: 1542 RPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRK-PGAQPRKRKTKQ 1600
V +++ QP P Q GS G+ + + RR+ P +P + ++ +
Sbjct: 2696 -----VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
Query: 1601 A 1601
+
Sbjct: 2751 S 2751
Score = 41.2 bits (95), Expect = 0.010
Identities = 89/411 (21%), Positives = 130/411 (31%), Gaps = 108/411 (26%)
Query: 336 TKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGEN 395
T PL + P P +S M + PSP++ + Q+PS S P Q
Sbjct: 2397 TSPPLLDRARSRTPPSAPSQSRMTSERA------PSPSSRMGQAPSQSLLPPAQDQP--- 2447
Query: 396 LQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAA----------GFKGFGLEGVPE 445
+ VP ++ L+ Q +P + A G GVP
Sbjct: 2448 ----RSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPH 2503
Query: 446 KRLTDP----GLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNS 501
+ +P G SAL+ S + + +S SSS S ++S
Sbjct: 2504 SDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS 2563
Query: 502 EGSS---QPEEQLK---SPM-----------------------AESLDGGCSSSSEDQGE 532
EGSS QPE LK SP + S SSSS
Sbjct: 2564 EGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSS 2623
Query: 533 RVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPL- 591
S S+SS ++ +S + SPA+ PG + +P
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSPSPAK---------------------PGPQALPKP 2662
Query: 592 SSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHAS 651
+S P E R + + R +D S P +RP
Sbjct: 2663 ASPKKPPPGE--------RRSRSPRKPIDSLRDSRSLSYSPVERRRPS------------ 2702
Query: 652 LPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSP 702
PQP P ++ ++S+ G GQ G S + R PS P
Sbjct: 2703 -PQPSP---------RDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRP 2743
Score = 38.9 bits (89), Expect = 0.049
Identities = 96/467 (20%), Positives = 158/467 (33%), Gaps = 89/467 (19%)
Query: 1153 HDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWD-----LSRQTSPAKSSGPPGMS 1207
H+ + RCL + + +G E Q++QE L + +P PG
Sbjct: 60 HERKRRVELRCLELEEMMEEQGYE----EQQIQEKVATFRLMLLEKDVNPGGKEETPGQR 115
Query: 1208 SQKRYGPPHETDGHGLAEATQ--SSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIP 1265
P T+ H LAE + + + + D SS +P +RR R P P
Sbjct: 116 -------PAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDP---QRRAREAKQPAP 165
Query: 1266 SKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDS 1325
+ + S+ + + K+ K S S + K+ S K +S
Sbjct: 166 EPPKPYSLVRESSSSRSP---TPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222
Query: 1326 RNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTVTLDD- 1384
+ + K+K RK + K + +P RR+ S SA++ + T
Sbjct: 223 ESKKRKHRSPTPKSK----RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
Query: 1385 -----------ILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRS 1433
L+ +S P G DA + G ++ P++ E ++P S
Sbjct: 279 SRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE-PGTTSTQ--RPSSPETATKQP---S 332
Query: 1434 SEEWRGSVDDKVKTETHA----ETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPL 1489
S D K K+ T E + G EPP A T +++ G G PL
Sbjct: 333 SPYEDKDKDKKEKSATRPSPSPERSSTGPEPP-APTPLLAERHG----------GSPQPL 381
Query: 1490 IFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNK 1549
P ++E N SP ++ PPK S +K
Sbjct: 382 A----------------TTPLSQEPVNPPSEASPTRDRSPPK----SPEKL--------P 413
Query: 1550 QKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKR 1596
Q + PP PQP ++ ++ PK R+ + P +
Sbjct: 414 QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSK 460
Score = 36.2 bits (82), Expect = 0.32
Identities = 270/1367 (19%), Positives = 445/1367 (32%), Gaps = 202/1367 (14%)
Query: 353 PVRSPMQFHQNFSPISNP-SPAASVVQSPSCSS--TPSPLMQTGENLQCGQGSVPMGSRN 409
P +SP + Q+ S S+P SP + V + SS +P P G + + +
Sbjct: 405 PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSH 464
Query: 410 RILQLMPQLSPTPSM-MPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPN 468
+ S TPS M S A +G P KR S S
Sbjct: 465 GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524
Query: 469 TVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSS-- 526
+ + +PQ RP S+ + T G S+ + +S G S S
Sbjct: 525 SRSPQRRGRSRSPQ-----RPGWSRSRN--TQRRGRSRSARRGRSHSRSPATRGRSRSRT 577
Query: 527 -SEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNA---SPAAREEAT 582
+ R R + + + S T + + + + + P R + SP R +
Sbjct: 578 PARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRS 637
Query: 583 SPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPA----ATQRP 638
A+ S P ++ +R + R P + S+ PA + R
Sbjct: 638 RSPARRSGRSRSRTPARRGRSRSRTPARRGRS-RSRTPARRSGRSRSRTPARRGRSRSRT 696
Query: 639 PSNGGAKETS-------HASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSG------H 685
P G ++ S H+ PQ G S+ KN S N
Sbjct: 697 PRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSE-RKNKSRTSQRRSRSNSSPEMKKSRIS 755
Query: 686 SAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGE---- 741
S +S +KS SLR S S S P+ S P P G +
Sbjct: 756 SRRSRSLSSPRSKAKSRLSLRRSLSGS--SPCPKQKSQTP--PRRSRSGSSQPKAKSRTP 811
Query: 742 -RKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELAS 800
R+ R+ P Q+ P R+ S+ H + GT P S T+ A+
Sbjct: 812 PRRSRSSSSPPPKQK-----SKTPSRQSHSSSSPHPKVKS---GT--PPRQGSITSPQAN 861
Query: 801 RGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYPIPRKFEIEPQSSA---HEPG 857
+ S E SS PE+K + + +SS P
Sbjct: 862 EQSVTPQRRSCFE-----------SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPS 910
Query: 858 GSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRLNPTLSQSVILPGGLVSM 917
S S + V ISP ++ +HS + +R+ R P S+SV + S
Sbjct: 911 RSSSPQPKVKAIISPRQR------SHSGSSSPSPSRV--TSRTTPRRSRSVSPCSNVESR 962
Query: 918 ETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHESYRGNASPGAATHDSLSD 977
S SG + + K + SG P +K ++ PG + S S
Sbjct: 963 LLPRYSHSGSSSPDT--KVKPETPPRQSHSGSISPYPKVKAQT-----PPGPSLSGSKSP 1015
Query: 978 YGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRS------RGPGGDPH 1031
+ S+ + ++ PG + G++ +P F G+S R P
Sbjct: 1016 CPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPE 1075
Query: 1032 HMNPH------MTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLHY 1085
H + S+ + + SP +E + + R P L S +
Sbjct: 1076 VRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPM--LKSGMSP 1133
Query: 1086 KRQMYQQQPEEYKDWSSGS--AQGVIAAAQHR-------QEGPRKSPRQQQ--------- 1127
++ +Q Y S S Q + A+ + QE SP +Q+
Sbjct: 1134 EQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQ 1193
Query: 1128 --------FLDRVRSPLKNDKDGMMYGPPVGTYHDP---SAQEAGRCLMSSDGLPNKGME 1176
F D +R+P + ++ G P + S+Q+ + G
Sbjct: 1194 DRPESSLVFKDTLRTPPR-ERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQI 1252
Query: 1177 LKHGSQKLQESCW-------------------DLSRQTSPAKSSGPPGMSSQ---KRYGP 1214
L H S +L+E D S+ + ++ P M+S + P
Sbjct: 1253 LSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSP 1312
Query: 1215 PHETDGHGLAEATQSSKPGSVMLRLP-GQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDV 1273
H+ + P P G E ++ + + F++ + + S D+
Sbjct: 1313 EHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETD-PSLDM 1371
Query: 1274 KNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDSRNCPAVTL 1333
K ST G HSS E + A A +S +Q I S P D+ PS + + +
Sbjct: 1372 KEQSTRSSG---HSSSELSPDAVEK-AGMSSNQSISS-PVLDAVPRTPSRERSS----SA 1422
Query: 1334 TSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEA-GGDTVTLDDILSLKSGP 1392
+SP LP R + + SP +R + + S + G + + DI P
Sbjct: 1423 SSPEMKDGLPRTPSRRSRSGS------SPGLRDGSGTPSRHSLSGSSPGMKDI---PRTP 1473
Query: 1393 PEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAE 1452
G S + + SP++ EL+ + P+ R + V +T A
Sbjct: 1474 SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRE---RSGSESSVDQKTVAR 1530
Query: 1453 TVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAE 1512
T + G+ + S Q R + PDSK + + +
Sbjct: 1531 TPLGQRSRSGSSQELDVKPSASPQERSESDSS-------PDSKAKTRTPLRQRSRSGSSP 1583
Query: 1513 EKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIP----- 1567
E ++ + +SP++ G P K K R + P P P P +P
Sbjct: 1584 EVDSKS-RLSPRRSR---SGSSPEVKDKPRAAPRA-QSGSDSSPEPKAPAPRALPRRSRS 1638
Query: 1568 -----------EGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVP 1603
EGS+ E P+ + R R+ + KTK P
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTP 1685
Score = 35.8 bits (81), Expect = 0.42
Identities = 45/196 (22%), Positives = 71/196 (36%), Gaps = 13/196 (6%)
Query: 57 GGRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQ 116
G + ++ A A S H G A + + P +TG QP P +
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLSV--PAPGVPHSDVGEPPASTGAQQPSALAALQPAK 2528
Query: 117 SYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQ 176
SS + S + S G S + + P P A + + +
Sbjct: 2529 ERRSSSSSSSSSSSSSSS--SSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586
Query: 177 QQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQ 236
++ V++ R +P P + +SSSS S+ SS++
Sbjct: 2587 KEAVREGRPP-----EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSSS 2637
Query: 237 SSASSSSSSSFPSPQR 252
SS+SSSSSSS PSP +
Sbjct: 2638 SSSSSSSSSSSPSPAK 2653
Score = 34.3 bits (77), Expect = 1.2
Identities = 66/331 (19%), Positives = 121/331 (36%), Gaps = 50/331 (15%)
Query: 449 TDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKR---PSSSKKADSCTNSEGSS 505
T P S S ++++ A P++ S +L P + R PS+ C ++ +
Sbjct: 2409 TPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP 2468
Query: 506 QPEEQLKSPMAESLDGGCSSSSEDQGERVRQLS------GQSTSSDTTYKGGASEK---A 556
Q S G ++++ G+ LS S + GA + A
Sbjct: 2469 VAGSQSLS------SGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALA 2522
Query: 557 GSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGR 616
PA+ ++ ++S ++ ++S + SS G+ + + + V E R
Sbjct: 2523 ALQPAKERRSS----SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578
Query: 617 VEKPGGQDKGS------QEDDPAATQRPPSNGGAKETSHASLPQPEPPGGGGSKGNKNGD 670
V P K + E PA +R S+ + +S +S S + +
Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSS----SSSSSSSSSSSSSSS 2634
Query: 671 NNSNHNGEGNGQSGHSAAGPGFTSRTEP------------SKSP----GSLRYSYKDSFG 714
++S+ + + S S A PG + +P S+SP SLR S S+
Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694
Query: 715 SAVPRNVSGFPQYPTGQEKGDFTGHGERKGR 745
R S PQ ++ + G R+G+
Sbjct: 2695 PVERRRPS--PQPSPRDQQSSSSERGSRRGQ 2723
Score = 32.0 bits (71), Expect = 6.0
Identities = 50/223 (22%), Positives = 70/223 (31%), Gaps = 29/223 (13%)
Query: 1101 SSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEA 1160
SS S+ ++ EG + + L RV SP K+ + G P P A
Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP------PEPTPA 2601
Query: 1161 GRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPHETDG 1220
R SS + S S S +S + SS SS P
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSS----SSSSSSSSSSSSSSSSSSSSPSP------ 2651
Query: 1221 HGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVKNSSTED 1280
+KPG L P S + P RR RS PI S R S+ + S E
Sbjct: 2652 ---------AKPGPQALPKPA----SPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVER 2698
Query: 1281 KGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSP 1323
+ S + + + P ++ PSP
Sbjct: 2699 RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 60.1 bits (144), Expect = 2e-08
Identities = 102/357 (28%), Positives = 130/357 (36%), Gaps = 57/357 (15%)
Query: 104 PQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSG--LGGVSHYQQDYTG--- 158
PQPPQ PSGP + G PQ Q GS G F Q G +S + Q G
Sbjct: 167 PQPPQPAPSGP-PAQGHPQHM---QQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQ 222
Query: 159 --PFSPGSAQYQQQASSQQQQQQVQQLRQQLYQ-SHQPLPQATGQPASSSSHL--QPMQR 213
PF S QQ LR + Q H P G+ + S P Q+
Sbjct: 223 GNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVAHSPRFSPNPPQQ 282
Query: 214 PSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSY-NVNAGSQY 272
+ P Q+ SS S + PSP + SGQ Y N+N G
Sbjct: 283 GAVRP-----------------QTLNFSSRSQTVPSP-TINNSGQYSRYPYSNLNQGLV- 323
Query: 273 EGHNVGSNAQAYGTQSNYSYQPQSMKNFEQA-KIPQGTQQGQQQQQPQQQQHPSQHVMQY 331
+N G N Q G +N + QS+ + A P + QG QQP HPS + Q
Sbjct: 324 --NNTGMN-QNLGLTNN-TPMNQSVPRYPNAVGFPSNSGQGLMHQQP---IHPSGSLNQ- 375
Query: 332 TNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPS---- 387
N T P Q Q G Y P P SPM+ N P P P P + P
Sbjct: 376 MNTQTMHPSQPQ-GTYASP--PPMSPMKAMSN--PAGTPPPQV----RPGSAGIPMEVGS 426
Query: 388 -PLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGV 443
P M + G++ +G RN + M Q P M +P + G GV
Sbjct: 427 YPNMPHPQPSHQPPGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGV 483
Score = 35.0 bits (79), Expect = 0.71
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 14/105 (13%)
Query: 1492 PDSKNVP--PVGILAPEANPKAEEKENDTVTISPKQE----GFPPKGYFPSGKKK---GR 1542
P K P P AP+ + +EK+ T T PK P + KKK G+
Sbjct: 659 PKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGK 718
Query: 1543 PIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERR 1587
GS N + PP PPP+ + P G K + RQ + +R
Sbjct: 719 TEGSENSDLDKTPPPSPPPEEDEDP-----GVQKRRSSRQVKRKR 758
Score = 32.3 bits (72), Expect = 4.6
Identities = 39/174 (22%), Positives = 69/174 (39%), Gaps = 44/174 (25%)
Query: 1510 KAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEG 1569
K ++K+N+ + +GF K FP G V+ Q ++
Sbjct: 597 KKKKKKNNHIVAEDPSKGFG-KDDFPGG---------VDNQ--------------ELNRN 632
Query: 1570 SADGEPKPKKQRQRRERRKPGAQPRKRKTKQ--------AVPIVEPQEPEIKLKYATQPL 1621
S DG + KK+++R + +K +P++ K K+ P + P+EP+ K P
Sbjct: 633 SLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKI-PKEPKEKKAKTATPK 691
Query: 1622 DKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPS 1675
K+ K+ + P E A+ +N + E ++ TPPPS
Sbjct: 692 PKSSKKSSNKKP------DSEASALKKKVNKGKTEGSE-----NSDLDKTPPPS 734
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 58.5 bits (140), Expect = 6e-08
Identities = 102/465 (21%), Positives = 156/465 (33%), Gaps = 85/465 (18%)
Query: 1400 VQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKE 1459
++ A + +RK + + A ++ S EE K A+ V
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGL--- 114
Query: 1460 PPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTV 1519
PPG + S+ S + D P K V P A KA+ ++D+
Sbjct: 115 PPGKAAAKASESSSSEESSDDDDEEDQKKQ--PVQKGVKPQAKAAKAPPKKAKSSDSDSD 172
Query: 1520 TISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEG---SADGEPK 1576
+ S E PPK P I V + + + PP P P+I G S+
Sbjct: 173 SSS---EDEPPKNQKPK-------ITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSS 222
Query: 1577 PKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQPLDKTDAKNKSFYPYIH 1636
E K A P+K K+ V P +K AT P K+ + S
Sbjct: 223 SSSSSDDSEEEKAAATPKKTVPKKQVVAKAP------VKAATTPTRKSSSSEDSS----- 271
Query: 1637 VVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESKAL-----PASSFMLQG 1691
+ EEEEQ K ++ + G S PPPS+ K P + Q
Sbjct: 272 --------------SDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQ 317
Query: 1692 PVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK----RATEMQS 1747
PV ESS + D D ++ K PP K +AT
Sbjct: 318 PV--ESS----------------EDSSD------ESDSSSEEEKKPPTKAVVSKATTKPP 353
Query: 1748 KVKVRHKSASNGSKTDTEEEEE--------QQQQQKEQRSLAAHPRFK-RRHRSEDCGGG 1798
K +S+S+ S +D+ E++E + + P K + GGG
Sbjct: 354 PAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG 413
Query: 1799 PRSLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIP 1843
+ L+R + E SS + K T + + L +P
Sbjct: 414 QKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLP 458
Score = 47.0 bits (110), Expect = 2e-04
Identities = 103/535 (19%), Positives = 190/535 (35%), Gaps = 54/535 (10%)
Query: 1156 SAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPP 1215
SA+ R L ++ + K + S S + Q PAK + P KR G P
Sbjct: 60 SAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPA----KRVGLP 115
Query: 1216 HETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVKN 1275
G A+A++SS S E+ + P+ + ++ + P K+ +
Sbjct: 116 ---PGKAAAKASESSS--SEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSD 170
Query: 1276 SSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTS 1335
S + + + K + + ++ PK + K S S + + + S
Sbjct: 171 SDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDS 230
Query: 1336 PAKTKILPPRKG---RGLKLEAIVQKITSPNIRRSASSNSAEAGGDTVTLDDILSLKSGP 1392
+ P+K + + +A V+ T+P + S+S +S+ + + +K+ P
Sbjct: 231 EEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEE----EQKKPMKNKP 286
Query: 1393 PEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRS---SEEWRGSVDDKVKTET 1449
SV A K+ S P + + ++P+ S S+E S +++ K T
Sbjct: 287 GPYSSVPPPSAPPPKK-----SLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPT 341
Query: 1450 HAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPL-IFPDSKNVPPVGILAPEAN 1508
A A +PP A + S S+ + + P +S N P V +P
Sbjct: 342 KAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVK 401
Query: 1509 PKAEEKE----NDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPP 1564
P A K+ + + S ++K + + + K K + P
Sbjct: 402 PAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAK- 460
Query: 1565 QIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQPLDKT 1624
Q P+GS D E K K+K ++ P +P A+ K
Sbjct: 461 QAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKP------ASAKKGKA 514
Query: 1625 DAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTES 1679
++ N S + ++ EEE+ KL +G+ R P + T +
Sbjct: 515 ESSNSS-----------------SSDDSSEEEEEKL-KGKGSPRPQAPKANGTSA 551
Score = 45.1 bits (105), Expect = 7e-04
Identities = 70/344 (20%), Positives = 123/344 (35%), Gaps = 28/344 (8%)
Query: 475 LSDALTPQKKTSKRPSSSKKAD---SCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQG 531
L A P++K +KKA S ++SE SS+ EE+++ P A+ G
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG 117
Query: 532 ERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPL 591
+ + S +S+SS+ + E P Q + P+ A+ A ++A S + D
Sbjct: 118 KAAAKAS-ESSSSEESSDDDDEEDQKKQPVQ--KGVKPQAKAAKAPPKKAKSSDS-DSDS 173
Query: 592 SSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQ----DKGSQEDDPAATQRPPSNGGAKET 647
SS+ P N+K V+ +A T KP G +++ S+ ++E
Sbjct: 174 SSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEE 233
Query: 648 SHASLPQ----------PEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTE 697
A+ P+ P + K+ + + + E Q PG S
Sbjct: 234 KAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVP 293
Query: 698 PSKSPGSLRYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVL 757
P +P K S G+ P+ Q E D + + EK P V
Sbjct: 294 PPSAPPP-----KKSLGTQPPKKAVEKQQPVESSE--DSSDESDSSSEEEKKPPTKAVVS 346
Query: 758 QGYHHHPDRRYSRSTQEHQGMAGSLEGTTRPNVLVSQTNELASR 801
+ P + + + + S E P+ T +++
Sbjct: 347 KATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNK 390
Score = 39.7 bits (91), Expect = 0.029
Identities = 50/236 (21%), Positives = 89/236 (37%), Gaps = 24/236 (10%)
Query: 481 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 540
P+K K+ DS S+ SS EE+ K P + +++ ++ + S
Sbjct: 309 PKKAVEKQQPVESSEDSSDESDSSS--EEEKKPPTKAVVSK--ATTKPPPAKKAAESSSD 364
Query: 541 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 600
S+ SD++ A K + + + N+P SPA + A A P+ G K
Sbjct: 365 SSDSDSSEDDEAPSKPAGT-TKNSSNKPAVTTKSPAVKPAA----APKQPVG--GGQK-- 415
Query: 601 EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660
+++R+A + E+ + + AT +P + A SLP + P G
Sbjct: 416 ------LLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAA----LSLPAKQAPQG 465
Query: 661 GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSA 716
+ + ++S E +S PSK P S + +S S+
Sbjct: 466 SRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSK-PASAKKGKAESSNSS 520
Score = 37.0 bits (84), Expect = 0.19
Identities = 41/221 (18%), Positives = 75/221 (33%), Gaps = 13/221 (5%)
Query: 481 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKS----PMAESLDGGCSSSSEDQ-----G 531
P KK ++ S S +DS + E S+P K+ P + ++ + G
Sbjct: 354 PAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG 413
Query: 532 ERVRQLSGQSTSSDTTYKGGASEKA----GSSPAQGAQNEPPRLNASPAAREEATSPGAK 587
+++ S+SS+ EK ++ + L A A + S
Sbjct: 414 QKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDS 473
Query: 588 DMPLSSDGNPKVNEKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKET 647
D S + K ++ V + A KP KG E +++ S ++
Sbjct: 474 DSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL 533
Query: 648 SHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAA 688
P+P+ P G+ + + N E + AA
Sbjct: 534 KGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAA 574
Score = 36.6 bits (83), Expect = 0.24
Identities = 71/331 (21%), Positives = 115/331 (34%), Gaps = 38/331 (11%)
Query: 1263 PIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPK-RDSSKDLP 1321
P+ S S D +SS+E++ + +K KA + + S DSS+D
Sbjct: 318 PVESSEDSSDESDSSSEEEKK--PPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDE 375
Query: 1322 SP--------DSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSA 1373
+P +S N PAVT SPA P++ G + + +K S + +SS+
Sbjct: 376 APSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEE 435
Query: 1374 EAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRS 1433
E T + K+ S+ + A R SD S +E K +
Sbjct: 436 E---KTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKK 492
Query: 1434 SEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPD 1493
+ V A E + +S S + + + GS AP
Sbjct: 493 KPQ---KVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGT 549
Query: 1494 SKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQ 1553
S G A + + EEK+ V +S GS+ K+K+
Sbjct: 550 SALTAQNGKAAKNSEEEEEEKKKAAVVVSKS--------------------GSLKKRKQN 589
Query: 1554 Q-QPPPPPPQPPQIPEGSADGEPKPKKQRQR 1583
+ PQ +I + + PK KK +R
Sbjct: 590 EAAKEAETPQAKKIKLQTPNTFPKRKKGEKR 620
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 58.5 bits (140), Expect = 6e-08
Identities = 64/237 (27%), Positives = 89/237 (37%), Gaps = 39/237 (16%)
Query: 149 VSHYQQDYTGP---------FSPGSAQYQQQASSQQQQ----------QQVQQLRQQLYQ 189
V+H QQ +T +P + QQQ +QQQQ QQ+ QL+QQ Q
Sbjct: 374 VNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQ 433
Query: 190 --SHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSF 247
S QP PQ P S Q Q+ P + QL+ Q H
Sbjct: 434 QISQQPYPQQPPHPFSQ----QQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
Query: 248 PSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQ 307
P Q+ + Q + Q + H + A Q + Q Q + +Q ++
Sbjct: 490 PFQQQHALQQQFH----------QLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQL-- 537
Query: 308 GTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNF 364
+ QQQQQ Q Q + H+ Q + A Q Q Q + P SP Q HQ F
Sbjct: 538 -QRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQ-HQLF 592
Score = 55.5 bits (132), Expect = 5e-07
Identities = 64/215 (29%), Positives = 81/215 (37%), Gaps = 40/215 (18%)
Query: 166 QYQQQASSQQQQ--------QQVQQLRQQLYQ--SHQPLPQATGQPASSSSHLQPMQRPS 215
Q QQQA QQQQ QQ+ QL+QQ Q S QP PQ P S Q Q+
Sbjct: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQ----QQQQQQQ 457
Query: 216 TLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGH 275
P + QL+ Q H PQ+ + Q +A Q
Sbjct: 458 AHPHQFSQQQLQFPQQQLH--------------PPQQLHRPQQQLQPFQQQHALQQ---- 499
Query: 276 NVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAA 335
Q + Q + Q Q + +Q + Q QQ QQQ Q QQ Q Q Q +
Sbjct: 500 ------QFHQLQQHQLQQQQLAQLQQQHSLLQ--QQQQQQIQQQQLQRMHQQQQQQQMQS 551
Query: 336 TKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNP 370
P SQ Q Q +VP + P Q Q P +P
Sbjct: 552 QTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSP 586
Score = 42.4 bits (98), Expect = 0.004
Identities = 54/202 (26%), Positives = 74/202 (36%), Gaps = 26/202 (12%)
Query: 138 QFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQA 197
Q Q Q Y Q PFS Q QQ Q QQQ+Q +QQL+ PQ
Sbjct: 426 QLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHP-----PQQ 480
Query: 198 TGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSG 257
+P LQP Q+ L +QL+ Q Q + S Q+ Q
Sbjct: 481 LHRP---QQQLQPFQQQHALQQQF--HQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQ 535
Query: 258 QSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQ 317
Q Q + + S + +Q++ + Q Q PQ Q QQQQQ
Sbjct: 536 QLQ------RMHQQQQQQQMQSQTAPHLSQTSQALQHQVP--------PQQPPQQQQQQQ 581
Query: 318 PQQQQHPSQHVMQYTNAATKLP 339
P P QH + + A ++P
Sbjct: 582 PPPS--PQQHQLFGHDPAVEIP 601
Score = 38.9 bits (89), Expect = 0.049
Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 5/72 (6%)
Query: 287 QSNYSYQPQSMKN---FEQAKIPQGTQQGQQQQQP--QQQQHPSQHVMQYTNAATKLPLQ 341
Q N+S Q + N F Q K+ T QQQQQ QQQQHP H+ + Q
Sbjct: 373 QVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQ 432
Query: 342 SQVGQYNQPEVP 353
Q+ Q P+ P
Sbjct: 433 QQISQQPYPQQP 444
Score = 35.4 bits (80), Expect = 0.55
Identities = 35/116 (30%), Positives = 46/116 (39%), Gaps = 16/116 (13%)
Query: 108 QRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQY 167
Q++ P Q PPQ + + + FQ QH+ QQ AQ
Sbjct: 465 QQQLQFPQQQLHPPQ-----QLHRPQQQLQPFQQQHALQQQFHQLQQHQLQ--QQQLAQL 517
Query: 168 QQQASSQQQQQQVQQLRQQLYQSHQPLPQA---------TGQPASSSSHLQPMQRP 214
QQQ S QQQQQ Q +QQL + HQ Q Q + + H P Q+P
Sbjct: 518 QQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQP 573
>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
Length = 1083
Score = 58.5 bits (140), Expect = 6e-08
Identities = 74/297 (24%), Positives = 103/297 (34%), Gaps = 39/297 (13%)
Query: 31 SPR-QAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASET-----SGHQGYQGFRK 84
SPR + M + GG G GS G GSGG RG + +T ++GY G K
Sbjct: 662 SPRISSPMHPSAGGQRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVK 721
Query: 85 EAGD----------FYYMAGNKDPVTTGTPQPPQRRPSGPVQSYG-PPQGSSFGNQYGSE 133
+A + ++ ++ +TT RRP G +YG P S YGS
Sbjct: 722 DATESTARVELHSTCQTISVDRQRLTT----VGSRRPGGMTSTYGRTPMYGSQTPMYGSG 777
Query: 134 GHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQ---- 189
+ +Q G P GS Q + ++ Y+
Sbjct: 778 SRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFD 837
Query: 190 ----------SHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSA 239
P PQ G P SS + P P T P + A Y QF + S
Sbjct: 838 DEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQT-PGTPAMY--NTDQFSPYAAPSP 894
Query: 240 SSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS 296
S S PSPQ + Q S G N ++ + Y QA + S Y P +
Sbjct: 895 QGSYQPS-PSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMT 950
Score = 36.2 bits (82), Expect = 0.32
Identities = 49/209 (23%), Positives = 67/209 (32%), Gaps = 43/209 (20%)
Query: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQ--QPQQQQHPSQ 326
GSQ + GS YG+Q+ ++ Q + G++ Q P PS+
Sbjct: 768 GSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSR 827
Query: 327 HVMQYTNAATKLPLQS---------------------QVGQYNQPEVPVRSPMQFHQNFS 365
+Y A P S QV P+ P M FS
Sbjct: 828 AEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFS 887
Query: 366 PISNPSPAASVVQSPSCSS----TPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPT 421
P + PSP S SPS S PSP + P + Q SP+
Sbjct: 888 PYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPS-------PMAYQASPS 940
Query: 422 PSMM---------PSPNSHAAGFKGFGLE 441
PS + PSP + G G+E
Sbjct: 941 PSPVGYSPMTPGAPSPGGYNPHTPGSGIE 969
Score = 33.5 bits (75), Expect = 2.1
Identities = 42/164 (25%), Positives = 50/164 (30%), Gaps = 38/164 (23%)
Query: 1455 TAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLI-----FPDSKNVPPVGILAP---- 1505
T G PG MTST + P P G P+ D P G P
Sbjct: 748 TVGSRRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDG 807
Query: 1506 -----------EANP----KAEEKE----NDTVTISPKQEGFPPKGYFPSGKKKGRPIGS 1546
NP +AEE+ +D T SP+ G P P P
Sbjct: 808 SRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSP--Q 865
Query: 1547 VNKQKKQQQPPPP--------PPQPPQIPEGSADGEPKPKKQRQ 1582
VN Q Q P P P P+GS P P+ Q
Sbjct: 866 VNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQ 909
>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 58.5 bits (140), Expect = 6e-08
Identities = 74/297 (24%), Positives = 103/297 (34%), Gaps = 39/297 (13%)
Query: 31 SPR-QAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASET-----SGHQGYQGFRK 84
SPR + M + GG G GS G GSGG RG + +T ++GY G K
Sbjct: 666 SPRISSPMHPSAGGQRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVK 725
Query: 85 EAGD----------FYYMAGNKDPVTTGTPQPPQRRPSGPVQSYG-PPQGSSFGNQYGSE 133
+A + ++ ++ +TT RRP G +YG P S YGS
Sbjct: 726 DATESTARVELHSTCQTISVDRQRLTT----VGSRRPGGMTSTYGRTPMYGSQTPMYGSG 781
Query: 134 GHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQ---- 189
+ +Q G P GS Q + ++ Y+
Sbjct: 782 SRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFD 841
Query: 190 ----------SHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSA 239
P PQ G P SS + P P T P + A Y QF + S
Sbjct: 842 DEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQT-PGTPAMY--NTDQFSPYAAPSP 898
Query: 240 SSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS 296
S S PSPQ + Q S G N ++ + Y QA + S Y P +
Sbjct: 899 QGSYQPS-PSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMT 954
Score = 36.2 bits (82), Expect = 0.32
Identities = 49/209 (23%), Positives = 67/209 (32%), Gaps = 43/209 (20%)
Query: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQ--QPQQQQHPSQ 326
GSQ + GS YG+Q+ ++ Q + G++ Q P PS+
Sbjct: 772 GSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSR 831
Query: 327 HVMQYTNAATKLPLQS---------------------QVGQYNQPEVPVRSPMQFHQNFS 365
+Y A P S QV P+ P M FS
Sbjct: 832 AEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFS 891
Query: 366 PISNPSPAASVVQSPSCSS----TPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPT 421
P + PSP S SPS S PSP + P + Q SP+
Sbjct: 892 PYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPS-------PMAYQASPS 944
Query: 422 PSMM---------PSPNSHAAGFKGFGLE 441
PS + PSP + G G+E
Sbjct: 945 PSPVGYSPMTPGAPSPGGYNPHTPGSGIE 973
Score = 33.5 bits (75), Expect = 2.1
Identities = 42/164 (25%), Positives = 50/164 (30%), Gaps = 38/164 (23%)
Query: 1455 TAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLI-----FPDSKNVPPVGILAP---- 1505
T G PG MTST + P P G P+ D P G P
Sbjct: 752 TVGSRRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDG 811
Query: 1506 -----------EANP----KAEEKE----NDTVTISPKQEGFPPKGYFPSGKKKGRPIGS 1546
NP +AEE+ +D T SP+ G P P P
Sbjct: 812 SRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSP--Q 869
Query: 1547 VNKQKKQQQPPPP--------PPQPPQIPEGSADGEPKPKKQRQ 1582
VN Q Q P P P P+GS P P+ Q
Sbjct: 870 VNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQ 913
>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 58.5 bits (140), Expect = 6e-08
Identities = 74/297 (24%), Positives = 103/297 (34%), Gaps = 39/297 (13%)
Query: 31 SPR-QAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASET-----SGHQGYQGFRK 84
SPR + M + GG G GS G GSGG RG + +T ++GY G K
Sbjct: 666 SPRISSPMHPSAGGQRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVK 725
Query: 85 EAGD----------FYYMAGNKDPVTTGTPQPPQRRPSGPVQSYG-PPQGSSFGNQYGSE 133
+A + ++ ++ +TT RRP G +YG P S YGS
Sbjct: 726 DATESTARVELHSTCQTISVDRQRLTT----VGSRRPGGMTSTYGRTPMYGSQTPMYGSG 781
Query: 134 GHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQ---- 189
+ +Q G P GS Q + ++ Y+
Sbjct: 782 SRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFD 841
Query: 190 ----------SHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSA 239
P PQ G P SS + P P T P + A Y QF + S
Sbjct: 842 DEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQT-PGTPAMY--NTDQFSPYAAPSP 898
Query: 240 SSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS 296
S S PSPQ + Q S G N ++ + Y QA + S Y P +
Sbjct: 899 QGSYQPS-PSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMT 954
Score = 36.2 bits (82), Expect = 0.32
Identities = 49/209 (23%), Positives = 67/209 (32%), Gaps = 43/209 (20%)
Query: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQ--QPQQQQHPSQ 326
GSQ + GS YG+Q+ ++ Q + G++ Q P PS+
Sbjct: 772 GSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSR 831
Query: 327 HVMQYTNAATKLPLQS---------------------QVGQYNQPEVPVRSPMQFHQNFS 365
+Y A P S QV P+ P M FS
Sbjct: 832 AEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFS 891
Query: 366 PISNPSPAASVVQSPSCSS----TPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPT 421
P + PSP S SPS S PSP + P + Q SP+
Sbjct: 892 PYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPS-------PMAYQASPS 944
Query: 422 PSMM---------PSPNSHAAGFKGFGLE 441
PS + PSP + G G+E
Sbjct: 945 PSPVGYSPMTPGAPSPGGYNPHTPGSGIE 973
Score = 33.5 bits (75), Expect = 2.1
Identities = 42/164 (25%), Positives = 50/164 (30%), Gaps = 38/164 (23%)
Query: 1455 TAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLI-----FPDSKNVPPVGILAP---- 1505
T G PG MTST + P P G P+ D P G P
Sbjct: 752 TVGSRRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDG 811
Query: 1506 -----------EANP----KAEEKE----NDTVTISPKQEGFPPKGYFPSGKKKGRPIGS 1546
NP +AEE+ +D T SP+ G P P P
Sbjct: 812 SRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSP--Q 869
Query: 1547 VNKQKKQQQPPPP--------PPQPPQIPEGSADGEPKPKKQRQ 1582
VN Q Q P P P P+GS P P+ Q
Sbjct: 870 VNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQ 913
>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 58.5 bits (140), Expect = 6e-08
Identities = 74/297 (24%), Positives = 103/297 (34%), Gaps = 39/297 (13%)
Query: 31 SPR-QAQMFQNFGGTGGSSGSSGSGSGGGRRGAAAAAAAMASET-----SGHQGYQGFRK 84
SPR + M + GG G GS G GSGG RG + +T ++GY G K
Sbjct: 666 SPRISSPMHPSAGGQRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVK 725
Query: 85 EAGD----------FYYMAGNKDPVTTGTPQPPQRRPSGPVQSYG-PPQGSSFGNQYGSE 133
+A + ++ ++ +TT RRP G +YG P S YGS
Sbjct: 726 DATESTARVELHSTCQTISVDRQRLTT----VGSRRPGGMTSTYGRTPMYGSQTPMYGSG 781
Query: 134 GHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQ---- 189
+ +Q G P GS Q + ++ Y+
Sbjct: 782 SRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFD 841
Query: 190 ----------SHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSA 239
P PQ G P SS + P P T P + A Y QF + S
Sbjct: 842 DEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQT-PGTPAMY--NTDQFSPYAAPSP 898
Query: 240 SSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS 296
S S PSPQ + Q S G N ++ + Y QA + S Y P +
Sbjct: 899 QGSYQPS-PSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMT 954
Score = 36.2 bits (82), Expect = 0.32
Identities = 49/209 (23%), Positives = 67/209 (32%), Gaps = 43/209 (20%)
Query: 269 GSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQ--QPQQQQHPSQ 326
GSQ + GS YG+Q+ ++ Q + G++ Q P PS+
Sbjct: 772 GSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSR 831
Query: 327 HVMQYTNAATKLPLQS---------------------QVGQYNQPEVPVRSPMQFHQNFS 365
+Y A P S QV P+ P M FS
Sbjct: 832 AEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFS 891
Query: 366 PISNPSPAASVVQSPSCSS----TPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPT 421
P + PSP S SPS S PSP + P + Q SP+
Sbjct: 892 PYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPS-------PMAYQASPS 944
Query: 422 PSMM---------PSPNSHAAGFKGFGLE 441
PS + PSP + G G+E
Sbjct: 945 PSPVGYSPMTPGAPSPGGYNPHTPGSGIE 973
Score = 33.5 bits (75), Expect = 2.1
Identities = 42/164 (25%), Positives = 50/164 (30%), Gaps = 38/164 (23%)
Query: 1455 TAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLI-----FPDSKNVPPVGILAP---- 1505
T G PG MTST + P P G P+ D P G P
Sbjct: 752 TVGSRRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDG 811
Query: 1506 -----------EANP----KAEEKE----NDTVTISPKQEGFPPKGYFPSGKKKGRPIGS 1546
NP +AEE+ +D T SP+ G P P P
Sbjct: 812 SRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSP--Q 869
Query: 1547 VNKQKKQQQPPPP--------PPQPPQIPEGSADGEPKPKKQRQ 1582
VN Q Q P P P P+GS P P+ Q
Sbjct: 870 VNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQ 913
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 58.5 bits (140), Expect = 6e-08
Identities = 122/525 (23%), Positives = 188/525 (35%), Gaps = 79/525 (15%)
Query: 199 GQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQ---RFSQ 255
G P +S + M P+T+ G + SSS + P+P+ R +
Sbjct: 164 GFPMASGPGIIRMNNPATVMIPPGG--------------NVSSSMMAPGPNPELQPRTPR 209
Query: 256 SGQSYDGSYNVNAGS--QYEGHNVGSNAQAYGTQSNYSYQPQSM-KNFEQAKIPQGTQQG 312
D + +G Q + H GS A + + QP S+ + A PQ QQ
Sbjct: 210 PASQSDAMDPLLSGLHIQQQSHPSGSLAPPH-----HPMQPVSVNRQMNPANFPQLQQQQ 264
Query: 313 QQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSP 372
QQQQQ QQQQ Q Q + LQ++ Q +Q + P QF +P P P
Sbjct: 265 QQQQQQQQQQQQQQQQQQ------QQQLQARPPQQHQQQQPQGIRPQF---TAPTQVPVP 315
Query: 373 AASVVQSPSCSSTPSPLMQTGENLQCGQG--SVPM-GSRNRILQLMPQLS--PTPSMMPS 427
Q PS + P P + + QG P+ G + LQ P L+ TPS P
Sbjct: 316 -PGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPP 374
Query: 428 PNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALST-QVANL---PNTVQHMLLSDALTPQK 483
P FG + + P +S+ + Q+ +L P+ V L LT K
Sbjct: 375 PYP-------FGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLT-NK 426
Query: 484 KTSKRPSSSKKADSCTNSEGSSQPEEQL--KSPMAESLDGGCSSSSEDQGERVRQLSGQS 541
+ PSS ++ S +S +Q ++Q+ + P L G G G
Sbjct: 427 SPASSPSSFQQG-SPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNV 485
Query: 542 TSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNE 601
+ + P QG Q+ P L P S G + P
Sbjct: 486 PPNFMVMQ-------QQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTA 538
Query: 602 KTVGVIVSREAMTGR-VEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 660
T G + + + V+ GGQ G ++ + PP ++ QP G
Sbjct: 539 TTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPP-----------NMMQPSLMGI 587
Query: 661 GGSKGNKNGDNN-----SNHNGEGNGQSGHSAAGPGFTSRTEPSK 700
G+ N+ + + N +G Q G + G + PS+
Sbjct: 588 HGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQ 632
Score = 48.1 bits (113), Expect = 8e-05
Identities = 111/464 (23%), Positives = 152/464 (32%), Gaps = 86/464 (18%)
Query: 83 RKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGPPQGSSFGNQYGSEGHVGQFQAQ 142
R EAG + MA + P P G V S G + Q + Q A
Sbjct: 160 RMEAG--FPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAM 217
Query: 143 HSGLGGVSHYQQDYTG--------PFSPGSA------------QYQQQASSQQQQQQVQQ 182
L G+ QQ + P P S Q QQQ QQQQQQ QQ
Sbjct: 218 DPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQ 277
Query: 183 LRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQF-GQHYQSSASS 241
+QQ Q Q P Q P+ +P QL G Q S +
Sbjct: 278 QQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGT 337
Query: 242 SSSS----SFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSM 297
+++ P P Q Q+ V S + QA +N+ PQ M
Sbjct: 338 MTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNF---PQ-M 393
Query: 298 KNFEQAKIPQ-GTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRS 356
N Q PQ + QG + P Q P TN + P S
Sbjct: 394 SNPGQFTAPQMKSLQGGPSRVPTPLQQP-----HLTNKS-----------------PASS 431
Query: 357 PMQFHQNFSPISNPSPAASVVQ--------SPSCSSTPSPLMQTGENLQCGQGSVPMGSR 408
P F Q SP S+P+ + Q +P P+ G N QG+VP
Sbjct: 432 PSSFQQG-SPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVP--PN 488
Query: 409 NRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPN 468
++Q P S+ P GL G+P KRL PG S+ A PN
Sbjct: 489 FMVMQQQPPNQGPQSLHP------------GLGGMP-KRL-PPGFSAGQA-------NPN 527
Query: 469 TVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLK 512
+Q + S T + + + +G+ P+ Q++
Sbjct: 528 FMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQ 571
Score = 47.0 bits (110), Expect = 2e-04
Identities = 69/253 (27%), Positives = 97/253 (38%), Gaps = 46/253 (18%)
Query: 293 QPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEV 352
QPQ +Q P Q QQQQQ QQQQ +MQ + +LP+ V P
Sbjct: 1004 QPQPQLPQQQQPPPPSQPQSQQQQQ-QQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLN 1062
Query: 353 P--VRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNR 410
P R PMQ + + + ASV SP P P+ + P+GS +R
Sbjct: 1063 PDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPV------------NTPLGSNSR 1110
Query: 411 --ILQLMPQ---LSPTPSMMPSPNSHAAGFKGFGLEG----------VPEKRL----TDP 451
+ Q PQ SP M P A+G + + G +P+ +L P
Sbjct: 1111 KMVYQESPQNPSSSPLAEMASLP--EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKP 1168
Query: 452 GLSSLSAL------STQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKK----ADSCTNS 501
G S LSA V +LP++ H + A Q K P+ + + N
Sbjct: 1169 GPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNR 1228
Query: 502 EGSSQPEEQLKSP 514
S++P E SP
Sbjct: 1229 PPSTEPSEISLSP 1241
Score = 41.6 bits (96), Expect = 0.008
Identities = 86/361 (23%), Positives = 120/361 (33%), Gaps = 52/361 (14%)
Query: 81 GFRKEAGDFYYMAGNKDPVTTGTPQ---PPQRRPSGPVQ-----SYGPPQGSSFGNQYGS 132
GF + +M G T TP PQ + + VQ GPPQ S
Sbjct: 518 GFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQ----MQVS 573
Query: 133 EGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQVQQLRQQLYQSHQ 192
G Q G+ G + QQ G++ Q S Q Q Q QL HQ
Sbjct: 574 HGPPNMMQPSLMGIHGNMNNQQ-------AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQ 626
Query: 193 PLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQR 252
+ + GQ L P Q P L + Q Q + S + PSPQR
Sbjct: 627 QIVPSQGQMVQQQGTLNP-QNPMILSRA---------QLMPQGQMMVNPPSQNLGPSPQR 676
Query: 253 FSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPQGT-QQ 311
+ Q SQ + + Q G Q Q M QG QQ
Sbjct: 677 MTPPKQML---------SQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQ 727
Query: 312 GQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPS 371
Q Q P+Q +M+ + + GQ + +P + P+ N SP
Sbjct: 728 FNTQNQSNVMPGPAQ-IMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV----NNSPSQVMG 782
Query: 372 PAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSH 431
V++ P PSP M Q G + + + Q+MP +S + M P+
Sbjct: 783 IQGQVLRPPG----PSPHMAQ----QHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQ 834
Query: 432 A 432
A
Sbjct: 835 A 835
Score = 40.8 bits (94), Expect = 0.013
Identities = 85/377 (22%), Positives = 134/377 (35%), Gaps = 61/377 (16%)
Query: 153 QQDYTGPFSPGSAQYQQQASSQQQQQQVQQ--------LRQQLYQSHQPL-PQATGQPAS 203
QQ P P S Q QQQ +QQ + Q ++ PL P + P
Sbjct: 1012 QQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQ 1071
Query: 204 SSSHLQPM---QRPSTLPSSAAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSY 260
S + M Q P+++P S ++ + ++S SPQ S S +
Sbjct: 1072 QSGSVPVMVSLQGPASVPPSPDKQRM---PMPVNTPLGSNSRKMVYQESPQNPSSSPLAE 1128
Query: 261 DGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQS---MKNFEQAKIPQGTQQGQQQQQ 317
S +GS+ G N ++ PQ+ M + P QG QQ
Sbjct: 1129 MASLPEASGSEAPSVPGGPN-----NMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQ 1183
Query: 318 PQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVV 377
P PS H + N A Q ++P+ P R+ + + +P + P
Sbjct: 1184 PPVNSLPSSHGHHFPNVAAPT-------QTSRPKTPNRASPRPYYPQTPNNRPP------ 1230
Query: 378 QSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMMPSPNSHAAGFKG 437
S+ PS + + E L I L P P + P PN + +G
Sbjct: 1231 -----STEPSEISLSPERLNAS-----------IAGLFPPQINIP-LPPRPNLN----RG 1269
Query: 438 FGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADS 497
F +G+ L G + S L+ +N H L S + K+++ S + K S
Sbjct: 1270 FDQQGLNPTTLKAIG-QAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSN---SGATKRAS 1325
Query: 498 CTNSEGSSQPEEQLKSP 514
+NS SS + +P
Sbjct: 1326 PSNSRRSSPGSSRKTTP 1342
Score = 38.1 bits (87), Expect = 0.084
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 12/130 (9%)
Query: 1466 STTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQ 1525
+T + KP + P L PD++ P G+ + P E+ + PK
Sbjct: 908 NTNANKPKKKKP-PRKKKNSQQDLNTPDTR---PAGLEEADQPPLPGEQGINLDNSGPKL 963
Query: 1526 EGFP--PKGYFPSGKKKGRPIGSVNKQKKQQ-QPPPPPPQ---PPQIPEGSADGEP-KPK 1578
F P GY PS + RP+ + Q Q PPP PPQ PQ+P+ P +P+
Sbjct: 964 PEFSNRPPGY-PSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQ 1022
Query: 1579 KQRQRRERRK 1588
Q+Q++++++
Sbjct: 1023 SQQQQQQQQQ 1032
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 57.4 bits (137), Expect = 1e-07
Identities = 102/424 (24%), Positives = 154/424 (36%), Gaps = 95/424 (22%)
Query: 162 PGSAQYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPS-- 219
P Y QQ QQQQQQ QQ +QQ Q Q Q Q SS S Q Q+ S++ +
Sbjct: 581 PSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQ 640
Query: 220 ------SAAGYQLRVGQFGQHYQSSASSSSSSSFP------SPQRFSQ-------SGQSY 260
Q + Q Q Q SS + S P SP Q Q
Sbjct: 641 QQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPI 700
Query: 261 DG-SYNVNAGSQYEGHN-VGSN---------AQAYGTQSNYSYQPQSMKNFE-------- 301
G Y V+ + + H+ VG N T S Y QS+ N +
Sbjct: 701 AGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTL 760
Query: 302 QAKIPQGTQQGQQQQQ---------PQQQ--QHPSQHVMQYTNAATKLPLQSQVGQYN-- 348
Q +I + QQ QQQ PQ Q +H S+ Y + + QY+
Sbjct: 761 QRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGG 820
Query: 349 ------QPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ-- 400
+ +P+ H +P S+ + + PS S+ + G NL C Q
Sbjct: 821 SSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYG-NLPCNQPN 879
Query: 401 ------GSVPMGSRNRILQLM-----PQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLT 449
G + + QL+ P + P++ PS N++ A FG V +
Sbjct: 880 TYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVA---TFGAGSVGNSQQL 936
Query: 450 DPGLSSLSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADSCTNSEGSSQPEE 509
P L+ +A++P PQ+ ++ +S+ A + + EG+S+ +E
Sbjct: 937 RPNLTH------SMASMP-------------PQRTSNVMITSNTTAPNWASQEGTSKQQE 977
Query: 510 QLKS 513
L S
Sbjct: 978 ALTS 981
Score = 36.2 bits (82), Expect = 0.32
Identities = 49/198 (24%), Positives = 70/198 (35%), Gaps = 34/198 (17%)
Query: 977 DYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSPGRSRGPGGDPH----H 1032
D G Q R TP +P K + SPG ++GP G P
Sbjct: 343 DLGQQSQRSTPRPSLP----------------MEKIVIKSEYSPGLTQGPSGSPQLRPPS 386
Query: 1033 MNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRA--------HAYGDPNAGLNSQLH 1084
P + + A +S P P S+ +RA HA N Q H
Sbjct: 387 AGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQH 446
Query: 1085 YKRQMYQQQPEEYKDWSS-GSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGM 1143
+ Q +QQQ + +WS+ S+ G +++ P S QQ F + SP+ G
Sbjct: 447 ARMQQHQQQ-HQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQ-SSPMPGVAGGS 504
Query: 1144 MYGPPVGTY---HDPSAQ 1158
+ Y PSAQ
Sbjct: 505 GQSKVMANYMYKAGPSAQ 522
Score = 36.2 bits (82), Expect = 0.32
Identities = 36/185 (19%), Positives = 65/185 (35%), Gaps = 7/185 (3%)
Query: 1026 PGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLNSQLHY 1085
P +P N F +++++ P S+ S H + Q
Sbjct: 547 PAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQ 606
Query: 1086 KRQMYQQQPEEYKDWSSGSAQ-------GVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKN 1138
++Q QQQ ++ + SS SAQ + A Q +Q+ ++ +QQQ + + +
Sbjct: 607 QQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQP 666
Query: 1139 DKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPA 1198
P P + L P GM + Q+ Q+ + + T P+
Sbjct: 667 SSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPS 726
Query: 1199 KSSGP 1203
S P
Sbjct: 727 PSPNP 731
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 57.0 bits (136), Expect = 2e-07
Identities = 95/463 (20%), Positives = 157/463 (33%), Gaps = 55/463 (11%)
Query: 1199 KSSGPPGMSSQKRYGPP-------------HETDGHGLAEATQSSKPGSVMLRLPGQEDH 1245
+ GPPG+S Q G P + G G E T+ + +L+ D
Sbjct: 138 REPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTG-PEDTEGGRHAPELLKHQLLGDL 196
Query: 1246 SSQNPLIMRRRVRSFISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHS 1305
+ P + + + +DV SS +D S A A + + +
Sbjct: 197 HQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQD------SPPSKASPAQDGRPPQTAA 250
Query: 1306 QDIKSIPKRDSSKDLPSPD------SRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKI 1359
++ SIP + +P P S PA P+ + KG+ LE
Sbjct: 251 REATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRA----KGQDAPLEFTFHVE 306
Query: 1360 TSPNIRRSASSNSAEAGGDTVTLDDILSLKS-GPPEGGSVAVQDADIEKRKGEVASDLVS 1418
+PN+++ + + G ++ GP G D K A+
Sbjct: 307 ITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK 366
Query: 1419 PANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGR 1478
P ++ ++ + S++ GS D K KT T + T P S PGS+
Sbjct: 367 PVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRP---CLSPKHPTPGSS--- 420
Query: 1479 PDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGK 1538
D + ++P + P+ + P + KE K + P+G P G+
Sbjct: 421 -DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQ 479
Query: 1539 KKGRPIGSVNKQKKQQQPPPPPPQPPQI----------PEGSADGEPKPKKQRQRRERRK 1588
K G N + + PP P PP P G +P K R
Sbjct: 480 K-----GQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSS 534
Query: 1589 PGA--QPRKRKTKQAVPIVEPQEPEIKLKYATQPLDKTDAKNK 1629
PG+ P R ++P +EP+ T P + AK++
Sbjct: 535 PGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSR 577
Score = 32.3 bits (72), Expect = 4.6
Identities = 58/279 (20%), Positives = 99/279 (35%), Gaps = 38/279 (13%)
Query: 483 KKTSKRPSSSKKADSCTNSEGSSQPEE------------QLKSPMAESLDGGCSSSSEDQ 530
K +++ P+S S ++G P E + ++ E L + +
Sbjct: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE 333
Query: 531 GERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEP----PRLNASPAAREEATSPGA 586
G R G S DT + E + PA + +P P+L A ++ +
Sbjct: 334 GPEAR---GPSLGEDTK-EADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSK-------S 382
Query: 587 KDMPLSSDGNPKVNEKTVG-VIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAK 645
KD S D K + ++ + +R ++ + PG D Q PA PPS+ K
Sbjct: 383 KDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSS--PK 440
Query: 646 ETSHASLPQPEPPGGGGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSL 705
S + G G+K K +G+ + AA PG + ++ P
Sbjct: 441 HVSSVT----SRTGSSGAKEMK----LKGADGKTKIATPRGAAPPGQKGQANATRIPAKT 492
Query: 706 RYSYKDSFGSAVPRNVSGFPQYPTGQEKGDFTGHGERKG 744
+ K SA + P E+G+ G+R G
Sbjct: 493 PPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSG 531
>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
sapiens]
Length = 758
Score = 56.2 bits (134), Expect = 3e-07
Identities = 92/451 (20%), Positives = 153/451 (33%), Gaps = 49/451 (10%)
Query: 1199 KSSGPPGMSSQKRYGPP-------------HETDGHGLAEATQSSKPGSVMLRLPGQEDH 1245
+ GPPG+S Q G P + G G E T+ + +L+ D
Sbjct: 138 REPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTG-PEDTEGGRHAPELLKHQLLGDL 196
Query: 1246 SSQNPLIMRRRVRSFISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHS 1305
+ P + + + +DV SS +D S A A + + +
Sbjct: 197 HQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQD------SPPSKASPAQDGRPPQTAA 250
Query: 1306 QDIKSIPKRDSSKDLPSPD------SRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKI 1359
++ SIP + +P P S PA P+ + KG+ LE
Sbjct: 251 REATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRA----KGQDAPLEFTFHVE 306
Query: 1360 TSPNIRRSASSNSAEAGGDTVTLDDILSLKS-GPPEGGSVAVQDADIEKRKGEVASDLVS 1418
+PN+++ + + G ++ GP G D K A+
Sbjct: 307 ITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK 366
Query: 1419 PANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGR 1478
P ++ ++ + S++ GS D K KT T + T P S PGS+
Sbjct: 367 PVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRP---CLSPKHPTPGSS--- 420
Query: 1479 PDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGK 1538
D + ++P + P+ + P + KE K + P+G P G+
Sbjct: 421 -DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQ 479
Query: 1539 KKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKT 1598
K G N + + PP P PP + GEP R P R
Sbjct: 480 K-----GQANATRIPAKTPPAPKTPP------SSGEPPKSGDRSGYSSPGSPGTPGSRSR 528
Query: 1599 KQAVPIVEPQEPEIKLKYATQPLDKTDAKNK 1629
++P +EP+ T P + AK++
Sbjct: 529 TPSLPTPPTREPKKVAVVRTPPKSPSSAKSR 559
Score = 32.0 bits (71), Expect = 6.0
Identities = 57/273 (20%), Positives = 92/273 (33%), Gaps = 64/273 (23%)
Query: 483 KKTSKRPSSSKKADSCTNSEGSSQPEE------------QLKSPMAESLDGGCSSSSEDQ 530
K +++ P+S S ++G P E + ++ E L + +
Sbjct: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE 333
Query: 531 GERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEP----PRLNASPAAREEATSPGA 586
G R G S DT + E + PA + +P P+L A ++ +
Sbjct: 334 GPEAR---GPSLGEDTK-EADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSK-------S 382
Query: 587 KDMPLSSDGNPKVNEKTVG-VIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPS----- 640
KD S D K + ++ + +R ++ + PG D Q PA PPS
Sbjct: 383 KDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHV 442
Query: 641 --------NGGAKE------TSHASLPQPEPPGGGGSKGNKNGDN-------------NS 673
+ GAKE + P G KG N +S
Sbjct: 443 SSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 502
Query: 674 NHNGEGNGQSGHSAAG----PGFTSRTEPSKSP 702
+ +SG+S+ G PG SRT +P
Sbjct: 503 GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP 535
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 56.2 bits (134), Expect = 3e-07
Identities = 41/184 (22%), Positives = 75/184 (40%), Gaps = 5/184 (2%)
Query: 478 ALTPQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQL 537
A T ++ T K A+ EG +P++ + E +++++++ +
Sbjct: 29 AATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPE 88
Query: 538 SGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNP 597
+ + A E+ ++P A E P+ + AA E+ +P A + P +G P
Sbjct: 89 KTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEP 148
Query: 598 KVNEKTVGVIVSREAMTGRV---EKPGGQDKG-SQEDDPAATQRPPSNGGAKETSHASLP 653
K E G KPG + S ++ PAAT+ P S A+ + AS
Sbjct: 149 KKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPA-ASAE 207
Query: 654 QPEP 657
+P+P
Sbjct: 208 EPKP 211
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,944,248
Number of Sequences: 37866
Number of extensions: 5561121
Number of successful extensions: 55286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 310
Number of HSP's successfully gapped in prelim test: 1120
Number of HSP's that attempted gapping in prelim test: 33394
Number of HSP's gapped (non-prelim): 15856
length of query: 1938
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1821
effective length of database: 13,817,196
effective search space: 25161113916
effective search space used: 25161113916
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.