Guide to the Human Genome
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Search of human proteins with 31652232

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31652232 T-box 5 isoform 1 [Homo sapiens]
         (518 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18201892 T-box 5 isoform 1 [Homo sapiens]                         1085   0.0  
gi|31652232 T-box 5 isoform 1 [Homo sapiens]                         1085   0.0  
gi|18201894 T-box 5 isoform 3 [Homo sapiens]                          983   0.0  
gi|18201896 T-box 5 isoform 2 [Homo sapiens]                          684   0.0  
gi|18129690 T-box 4 [Homo sapiens]                                    515   e-146
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]                  251   1e-66
gi|197333868 T-box 2 [Homo sapiens]                                   247   2e-65
gi|5174711 T-box 1 isoform B [Homo sapiens]                           242   5e-64
gi|117676399 T-box transcription factor TBX20 [Homo sapiens]          241   9e-64
gi|18104952 T-box 1 isoform C [Homo sapiens]                          241   2e-63
gi|18104950 T-box 1 isoform A [Homo sapiens]                          240   2e-63
gi|18201900 T-box 6 [Homo sapiens]                                    240   2e-63
gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]                  239   3e-63
gi|32567784 T-box 10 [Homo sapiens]                                   232   5e-61
gi|122937456 T-box 18 [Homo sapiens]                                  227   2e-59
gi|55770860 T-box 15 [Homo sapiens]                                   226   5e-59
gi|4507339 transcription factor T [Homo sapiens]                      209   4e-54
gi|122937388 MAX gene associated [Homo sapiens]                       207   1e-53
gi|7019549 T-box 21 [Homo sapiens]                                    200   2e-51
gi|158187509 T-box 22 isoform 1 [Homo sapiens]                        200   2e-51
gi|18375603 T-box 22 isoform 1 [Homo sapiens]                         200   2e-51
gi|5730081 T-box, brain, 1 [Homo sapiens]                             197   3e-50
gi|4827024 T-box 19 [Homo sapiens]                                    194   2e-49
gi|22538470 eomesodermin [Homo sapiens]                               192   8e-49
gi|158187511 T-box 22 isoform 2 [Homo sapiens]                        159   8e-39
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ...    43   8e-04
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ...    43   8e-04
gi|224994173 roundabout 1 isoform d [Homo sapiens]                     42   0.001
gi|224994171 roundabout 1 isoform c [Homo sapiens]                     42   0.001
gi|19743806 roundabout 1 isoform b [Homo sapiens]                      42   0.001

>gi|18201892 T-box 5 isoform 1 [Homo sapiens]
          Length = 518

 Score = 1085 bits (2805), Expect = 0.0
 Identities = 518/518 (100%), Positives = 518/518 (100%)

Query: 1   MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60
           MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE
Sbjct: 1   MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60

Query: 61  RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120
           RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK
Sbjct: 61  RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120

Query: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180
           WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ
Sbjct: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180

Query: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240
           PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD
Sbjct: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240

Query: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300
           DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP
Sbjct: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300

Query: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEEDSFYRSSYPQ 360
           SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEEDSFYRSSYPQ
Sbjct: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEEDSFYRSSYPQ 360

Query: 361 QQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDR 420
           QQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDR
Sbjct: 361 QQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDR 420

Query: 421 LPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQTGLQSPG 480
           LPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQTGLQSPG
Sbjct: 421 LPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQTGLQSPG 480

Query: 481 TLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 518
           TLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS
Sbjct: 481 TLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 518


>gi|31652232 T-box 5 isoform 1 [Homo sapiens]
          Length = 518

 Score = 1085 bits (2805), Expect = 0.0
 Identities = 518/518 (100%), Positives = 518/518 (100%)

Query: 1   MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60
           MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE
Sbjct: 1   MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60

Query: 61  RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120
           RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK
Sbjct: 61  RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120

Query: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180
           WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ
Sbjct: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180

Query: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240
           PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD
Sbjct: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240

Query: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300
           DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP
Sbjct: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300

Query: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEEDSFYRSSYPQ 360
           SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEEDSFYRSSYPQ
Sbjct: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEEDSFYRSSYPQ 360

Query: 361 QQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDR 420
           QQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDR
Sbjct: 361 QQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDR 420

Query: 421 LPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQTGLQSPG 480
           LPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQTGLQSPG
Sbjct: 421 LPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQTGLQSPG 480

Query: 481 TLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 518
           TLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS
Sbjct: 481 TLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 518


>gi|18201894 T-box 5 isoform 3 [Homo sapiens]
          Length = 468

 Score =  983 bits (2541), Expect = 0.0
 Identities = 468/468 (100%), Positives = 468/468 (100%)

Query: 51  MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 110
           MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD
Sbjct: 1   MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60

Query: 111 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 170
           DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH
Sbjct: 61  DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120

Query: 171 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 230
           IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN
Sbjct: 121 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 180

Query: 231 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 290
           PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ
Sbjct: 181 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 240

Query: 291 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE 350
           YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE
Sbjct: 241 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEE 300

Query: 351 DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC 410
           DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC
Sbjct: 301 DSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC 360

Query: 411 TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC 470
           TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC
Sbjct: 361 TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQC 420

Query: 471 GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 518
           GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS
Sbjct: 421 GPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS 468


>gi|18201896 T-box 5 isoform 2 [Homo sapiens]
          Length = 349

 Score =  684 bits (1764), Expect = 0.0
 Identities = 331/338 (97%), Positives = 332/338 (98%), Gaps = 4/338 (1%)

Query: 1   MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60
           MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE
Sbjct: 1   MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60

Query: 61  RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120
           RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK
Sbjct: 61  RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120

Query: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180
           WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ
Sbjct: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180

Query: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240
           PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD
Sbjct: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240

Query: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300
           DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP
Sbjct: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300

Query: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPY 338
           SQDLLPPPNPYPLPQEHSQIYHCTKRK E     DHP+
Sbjct: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKGE----CDHPW 334


>gi|18129690 T-box 4 [Homo sapiens]
          Length = 545

 Score =  515 bits (1326), Expect = e-146
 Identities = 293/525 (55%), Positives = 346/525 (65%), Gaps = 46/525 (8%)

Query: 28  PESALGAPSKS------PSSP-----QAAFTQQGMEGIKVFLHERELWLKFHEVGTEMII 76
           PE AL AP  S      P  P      AA  +Q +E IKV LHE+ELW KFHE GTEMII
Sbjct: 30  PEPALAAPGLSGAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMII 89

Query: 77  TKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLY 136
           TKAGRRMFPSYKVKVTG+NPKTKYILL+DIVPADDHRYKF DNKW V GKAEPAMPGRLY
Sbjct: 90  TKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLY 149

Query: 137 VHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNGFGS 196
           VHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENN FGS
Sbjct: 150 VHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGS 209

Query: 197 KNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYP 256
           KNTAFCTHVFPET+FI+VTSYQNHKITQLKIENNPFAKGFRGSDD +L R++R+QSKEYP
Sbjct: 210 KNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDL-RVARLQSKEYP 268

Query: 257 VVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVS---GPSQDLLPPPNPYPL 313
           V+ +S +RQ++ S     + +   L  +      YQ ENG        QDL  P + +P 
Sbjct: 269 VISKSIMRQRLISPQLSATPDVGPLLGTHQALQHYQHENGAHSQLAEPQDL--PLSTFPT 326

Query: 314 PQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPS-EEDSFYRSSYP-QQQGLGASYRTE 371
            ++ S  YHC KR+ +     D P K+ Y+E   S  ED ++RS  P  QQ L  SY +E
Sbjct: 327 QRDSSLFYHCLKRR-DGTRHLDLPCKRSYLEAPSSVGEDHYFRSPPPYDQQMLSPSYCSE 385

Query: 372 SAQRQACMYASSAPPSEPVPSLED-----ISCNTWPSMPSYSSCTVTTVQPMDRLPYQHF 426
              R+ACMY+ S P    V  ++D     +SCN W S+  Y+S    +VQ M+ +PYQ F
Sbjct: 386 VTPREACMYSGSGPEIAGVSGVDDLPPPPLSCNMWTSVSPYTS---YSVQTMETVPYQPF 442

Query: 427 SAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGP------QTGLQSPG 480
             HFT+  ++PRL  ++   S   G   F     ++ Q  VR+ GP      + GL    
Sbjct: 443 PTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLS-QSQVRERGPSASFPRERGLPQGC 501

Query: 481 TLQPP--------EFLYSHGVPRTL-SPHQYHSVHGVGMVPEWSD 516
             +PP        EFLYS     +  S  QYHS  G+G V  W+D
Sbjct: 502 ERKPPSPHLNAANEFLYSQTFSLSRESSLQYHS--GMGTVENWTD 544


>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
          Length = 723

 Score =  251 bits (641), Expect = 1e-66
 Identities = 162/424 (38%), Positives = 223/424 (52%), Gaps = 37/424 (8%)

Query: 55  KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114
           KV L  +ELW +FH+ GTEM+ITK+GRRMFP +KV+ +GL+ K KYILLMDI+ ADD RY
Sbjct: 104 KVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRY 163

Query: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILN 174
           KF +++W V GKA+P MP R+Y+HPDSPATG  WM ++V+F KLKLTNN  D  G  ILN
Sbjct: 164 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILN 223

Query: 175 SMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAK 234
           SMHKYQPR HIV+A  N+      + F T++FPET FIAVT+YQN KITQLKI+NNPFAK
Sbjct: 224 SMHKYQPRFHIVRA--NDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAK 281

Query: 235 GFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCE 294
           GFR + +    +  ++  +   V      ++   S+ S  SSE  A +  +   S     
Sbjct: 282 GFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDES--SSEQAAFNCFAQASSPAAST 339

Query: 295 NGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTT--DHPYKKPYMETSPSEEDS 352
            G S   +DL P         E  + +        + STT  + P +    + SP+ +  
Sbjct: 340 VGTSN-LKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRD---KGSPAVKAH 395

Query: 353 FYRSSYPQQQGLGASYRTESAQRQACMYASS---------APPSEPVPSLEDISCNTWPS 403
            + +  P+  G       +S    A + +S+         +P  E     +       P 
Sbjct: 396 LFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPG 455

Query: 404 MPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPL-----VPRLAGMANHGSPQLGEGMFQHQ 458
             +++  TV T            +AH   GPL      P LAG         G  +F H 
Sbjct: 456 KEAFAPLTVQT---------DAAAAHLAQGPLPGLGFAPGLAGQQFFN----GHPLFLHP 502

Query: 459 TSVA 462
           +  A
Sbjct: 503 SQFA 506


>gi|197333868 T-box 2 [Homo sapiens]
          Length = 712

 Score =  247 bits (630), Expect = 2e-65
 Identities = 121/183 (66%), Positives = 145/183 (79%), Gaps = 2/183 (1%)

Query: 55  KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114
           KV L  +ELW +FH++GTEM+ITK+GRRMFP +KV+V+GL+ K KYILLMDIV ADD RY
Sbjct: 106 KVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRY 165

Query: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILN 174
           KF +++W V GKA+P MP R+Y+HPDSPATG  WM + V+F KLKLTNN  D  G  ILN
Sbjct: 166 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILN 225

Query: 175 SMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAK 234
           SMHKYQPR HIV+A  N+      + F T+VFPET FIAVT+YQN KITQLKI+NNPFAK
Sbjct: 226 SMHKYQPRFHIVRA--NDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAK 283

Query: 235 GFR 237
           GFR
Sbjct: 284 GFR 286


>gi|5174711 T-box 1 isoform B [Homo sapiens]
          Length = 372

 Score =  242 bits (618), Expect = 5e-64
 Identities = 131/266 (49%), Positives = 175/266 (65%), Gaps = 15/266 (5%)

Query: 28  PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87
           P ++  A +K+P    A      + G+ V L  + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 89  PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143

Query: 88  KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145
           +VK+ G++P   Y+LLMD VP DD RY++A   + W V GKA+PA PGR++ HPDSPA G
Sbjct: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203

Query: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202
           A WM+Q+VSF KLKLTNN LD  GHIILNSMH+YQPR H+V  D   ++  +  +N  F 
Sbjct: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261

Query: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-S 261
           T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR  D  +  R  R  +   P++   +
Sbjct: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFA 319

Query: 262 TVRQKVASNHSPFSSESRALSTSSNL 287
             R  VAS   P  +E   ++  S L
Sbjct: 320 RSRNPVASPTQPSGTEKGLVTEGSGL 345


>gi|117676399 T-box transcription factor TBX20 [Homo sapiens]
          Length = 447

 Score =  241 bits (616), Expect = 9e-64
 Identities = 141/312 (45%), Positives = 189/312 (60%), Gaps = 26/312 (8%)

Query: 26  SKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFP 85
           S   S+L      P++P      + M  I   L  +ELW KFHE+GTEMIITK+GRRMFP
Sbjct: 74  SPSSSSLCTEPLIPTTP--IIPSEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFP 131

Query: 86  SYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK--WSVTGKAEPAMPGRLYVHPDSPA 143
           + +V  +G++P+ KYI+LMDIVP D+ RY++A ++  W V GKA+P +P RLYVHPDSP 
Sbjct: 132 TIRVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPF 191

Query: 144 TGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNG--FGSKNTAF 201
           TG   ++Q+VSF+K+KLTNN LD  GHIILNSMHKYQPR+HI+K  ++       K+  F
Sbjct: 192 TGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEF 251

Query: 202 CTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD---DMELHRM-SRMQSKEYPV 257
            T +FPET F AVT+YQN  IT+LKI++NPFAKGFR S    D+E   + S +Q   Y  
Sbjct: 252 RTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYAR 311

Query: 258 VPRSTV--RQKVASNHSPFS-SESRALSTSSNL-------------GSQYQCENGVSGPS 301
            P  T    + V  + S  + +   A +TS NL             G Q+       G S
Sbjct: 312 SPIRTYGGEEDVLGDESQTTPNRGSAFTTSDNLSLSSWVSSSSSFPGFQHPQSLTALGTS 371

Query: 302 QDLLPPPNPYPL 313
              +  P P+P+
Sbjct: 372 TASIATPIPHPI 383


>gi|18104952 T-box 1 isoform C [Homo sapiens]
          Length = 495

 Score =  241 bits (614), Expect = 2e-63
 Identities = 130/259 (50%), Positives = 172/259 (66%), Gaps = 15/259 (5%)

Query: 28  PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87
           P ++  A +K+P    A      + G+ V L  + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 89  PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143

Query: 88  KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145
           +VK+ G++P   Y+LLMD VP DD RY++A   + W V GKA+PA PGR++ HPDSPA G
Sbjct: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203

Query: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202
           A WM+Q+VSF KLKLTNN LD  GHIILNSMH+YQPR H+V  D   ++  +  +N  F 
Sbjct: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261

Query: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-S 261
           T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR  D  +  R  R  +   P++   +
Sbjct: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFA 319

Query: 262 TVRQKVASNHSPFSSESRA 280
             R  VAS   P  +E  A
Sbjct: 320 RSRNPVASPTQPSGTEKDA 338


>gi|18104950 T-box 1 isoform A [Homo sapiens]
          Length = 398

 Score =  240 bits (613), Expect = 2e-63
 Identities = 122/227 (53%), Positives = 159/227 (70%), Gaps = 12/227 (5%)

Query: 28  PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87
           P ++  A +K+P    A      + G+ V L  + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 89  PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143

Query: 88  KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145
           +VK+ G++P   Y+LLMD VP DD RY++A   + W V GKA+PA PGR++ HPDSPA G
Sbjct: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203

Query: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202
           A WM+Q+VSF KLKLTNN LD  GHIILNSMH+YQPR H+V  D   ++  +  +N  F 
Sbjct: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261

Query: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSR 249
           T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR  D  +  R  R
Sbjct: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHR 308


>gi|18201900 T-box 6 [Homo sapiens]
          Length = 436

 Score =  240 bits (613), Expect = 2e-63
 Identities = 114/202 (56%), Positives = 153/202 (75%), Gaps = 9/202 (4%)

Query: 38  SPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPK 97
           +PS+P+A  +   + G+ + L  RELW +F  VGTEMIITKAGRRMFP+ +V VTGL+P+
Sbjct: 78  APSAPEALHS---LPGVSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPE 134

Query: 98  TKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQK 157
            +Y+ L+D++P D  RY++   +W  +GKAEP +P R+Y+HPDSPATGAHWMRQ VSF +
Sbjct: 135 ARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHR 194

Query: 158 LKLTNNHLDPFGHIILNSMHKYQPRLHIVKADE--NNGFGSKNTAFCTHVFPETAFIAVT 215
           +KLTN+ LDP GH+IL+SMHKYQPR+H+V+A +  +  +G       +  FPET FI+VT
Sbjct: 195 VKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWG----GMASFRFPETTFISVT 250

Query: 216 SYQNHKITQLKIENNPFAKGFR 237
           +YQN +ITQLKI  NPFAKGFR
Sbjct: 251 AYQNPQITQLKIAANPFAKGFR 272


>gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
          Length = 743

 Score =  239 bits (611), Expect = 3e-63
 Identities = 162/444 (36%), Positives = 223/444 (50%), Gaps = 57/444 (12%)

Query: 55  KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114
           KV L  +ELW +FH+ GTEM+ITK+GRRMFP +KV+ +GL+ K KYILLMDI+ ADD RY
Sbjct: 104 KVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRY 163

Query: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFG----- 169
           KF +++W V GKA+P MP R+Y+HPDSPATG  WM ++V+F KLKLTNN  D  G     
Sbjct: 164 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAF 223

Query: 170 ---------------HIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAV 214
                            ILNSMHKYQPR HIV+A  N+      + F T++FPET FIAV
Sbjct: 224 PSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRA--NDILKLPYSTFRTYLFPETEFIAV 281

Query: 215 TSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPF 274
           T+YQN KITQLKI+NNPFAKGFR + +    +  ++  +   V      ++   S+ S  
Sbjct: 282 TAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDES-- 339

Query: 275 SSESRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTT 334
           SSE  A +  +   S      G S   +DL P         E  + +        + STT
Sbjct: 340 SSEQAAFNCFAQASSPAASTVGTSN-LKDLCPSEGESDAEAESKEEHGPEACDAAKISTT 398

Query: 335 --DHPYKKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASS--------- 383
             + P +    + SP+ +   + +  P+  G       +S    A + +S+         
Sbjct: 399 TSEEPCRD---KGSPAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERR 455

Query: 384 APPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPL-----VPR 438
           +P  E     +       P   +++  TV T            +AH   GPL      P 
Sbjct: 456 SPVREGTAPAKVEEARALPGKEAFAPLTVQT---------DAAAAHLAQGPLPGLGFAPG 506

Query: 439 LAGMANHGSPQLGEGMFQHQTSVA 462
           LAG         G  +F H +  A
Sbjct: 507 LAGQQFFN----GHPLFLHPSQFA 526


>gi|32567784 T-box 10 [Homo sapiens]
          Length = 385

 Score =  232 bits (592), Expect = 5e-61
 Identities = 135/308 (43%), Positives = 181/308 (58%), Gaps = 31/308 (10%)

Query: 23  PCDSKPES-ALGAPS-KSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAG 80
           PC S   + A+  P+ + P +P+ +        + V L  + LW +F+++GTEMI+TKAG
Sbjct: 39  PCTSSTGAQAVAEPTGQGPKNPRVS-------RVTVQLEMKPLWEEFNQLGTEMIVTKAG 91

Query: 81  RRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVH 138
           RRMFP ++VK+ G++    Y LLMD +P DD RY++A   + W V GKA+PA PGR++ H
Sbjct: 92  RRMFPPFQVKILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFH 151

Query: 139 PDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFG 195
           PDSPA GA WMRQ+VSF KLKLTNN LD  GHIILNSMH+YQPR H+V  D   ++  + 
Sbjct: 152 PDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSERYA 211

Query: 196 SKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEY 255
            +N  F + +F ET F AVT+YQNH+ITQLKI +NPFAKGFR SD              +
Sbjct: 212 QEN--FKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRESD-----------LDSW 258

Query: 256 PVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPS---QDLLPPPNPYP 312
           PV PR  +    A +HS  S      +T           +    P+     LLPPP    
Sbjct: 259 PVAPRPLL-SVPARSHSSLSPCVLKGATDREKDPNKASASTSKTPAWLHHQLLPPPEVLL 317

Query: 313 LPQEHSQI 320
            P  +  +
Sbjct: 318 APATYRPV 325


>gi|122937456 T-box 18 [Homo sapiens]
          Length = 607

 Score =  227 bits (579), Expect = 2e-59
 Identities = 119/246 (48%), Positives = 157/246 (63%), Gaps = 26/246 (10%)

Query: 5   DEGFGLAHTPL-EPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHEREL 63
           ++GF    +PL  P        ++  +  G P  SP +P            +V L   EL
Sbjct: 101 EDGFQQGASPLASPGGSPKGSPARSLARPGTPLPSPQAP------------RVDLQGAEL 148

Query: 64  WLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKW 121
           W +FHE+GTEMIITKAGRRMFP+ +VK++GL+P  +Y + MDIVP D+ RY++    +KW
Sbjct: 149 WKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKW 208

Query: 122 SVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQP 181
            V G A+  +P R+Y+HPDSPA+G  WMRQ++SF KLKLTNN LD  GHIIL+SMHKYQP
Sbjct: 209 MVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQP 268

Query: 182 RLHIVKADENNGF--------GSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233
           R+H+++ D  +          G    AF    FPET F  VT+YQN +IT+LKI+ NPFA
Sbjct: 269 RVHVIRKDCGDDLSPIKPVPSGEGVKAFS---FPETVFTTVTAYQNQQITRLKIDRNPFA 325

Query: 234 KGFRGS 239
           KGFR S
Sbjct: 326 KGFRDS 331


>gi|55770860 T-box 15 [Homo sapiens]
          Length = 496

 Score =  226 bits (575), Expect = 5e-59
 Identities = 139/354 (39%), Positives = 191/354 (53%), Gaps = 21/354 (5%)

Query: 51  MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 110
           ME I+V L   +LW +FH++GTEMIITKAGRRMFP+ +VK+TGL+P  +Y + MDIVP D
Sbjct: 4   MEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVD 63

Query: 111 DHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPF 168
           + RY++    +KW V G A+  +P R+Y+HPDS A+G  WMRQ+VSF KLKLTNN LD  
Sbjct: 64  NKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQ 123

Query: 169 GHIILNSMHKYQPRLHIVKADENNGFGSK-----NTAFCTHVFPETAFIAVTSYQNHKIT 223
           GHIIL+SMHKYQPR+H+++ D ++               T  FPET F  VT+YQN +IT
Sbjct: 124 GHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQIT 183

Query: 224 QLKIENNPFAKGFRGSDDMELHRMSRMQSKEY---PVVPRS----TVRQKVASNHSPFSS 276
           +LKI+ NPFAKGFR S        + M++  +   PV   +    T  QK     +  S 
Sbjct: 184 RLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSP 243

Query: 277 ESRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDH 336
            + +  T S   S +      S P+  L   PN + +    SQ+ +        C+ ++ 
Sbjct: 244 TTSSTGTPSPSASSHLLSPSCSPPTFHL--APNTFNVGCRESQLCNLNLSDYPPCARSNM 301

Query: 337 PYKKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYAS-SAPPSEP 389
              + Y    P   DS Y               T   QR   + +    PPS P
Sbjct: 302 AALQSY----PGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLP 351


>gi|4507339 transcription factor T [Homo sapiens]
          Length = 435

 Score =  209 bits (533), Expect = 4e-54
 Identities = 135/381 (35%), Positives = 187/381 (49%), Gaps = 34/381 (8%)

Query: 54  IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113
           ++V L E ELWL+F E+  EMI+TK GRRMFP  KV V+GL+P   Y  L+D V AD+HR
Sbjct: 42  LRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHR 101

Query: 114 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 173
           +K+ + +W   GK EP  P  +Y+HPDSP  GAHWM+  VSF K+KLTN  L+  G I+L
Sbjct: 102 WKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNK-LNGGGQIML 160

Query: 174 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233
           NS+HKY+PR+HIV+       G       +H FPET FIAVT+YQN +IT LKI+ NPFA
Sbjct: 161 NSLHKYEPRIHIVRV------GGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFA 214

Query: 234 KGFRGSDDMELHR--MSRMQSKEYP-------VVPRSTVRQKVASNHSPFSSESRALSTS 284
           K F  + +   H+  M      + P       ++P ++     A+ H  F     ALS  
Sbjct: 215 KAFLDAKERSDHKEMMEEPGDSQQPGYSQWGWLLPGTSTLCPPANPHPQFGG---ALS-- 269

Query: 285 SNLGSQYQCENGVSGPSQDLLPPPNPY------PLPQEHSQIYHCTKRKEEECSTTDHPY 338
             L S + C+   +  S    P P+PY      P   ++S       +  +  S+   P 
Sbjct: 270 --LPSTHSCDRYPTLRSHRSSPYPSPYAHRNNSPTYSDNSPACLSMLQSHDNWSSLGMPA 327

Query: 339 KKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSA-----PPSEPVPSL 393
               +  S +       S YP    +     T  +Q  A      A      P+   P  
Sbjct: 328 HPSMLPVSHNASPPTSSSQYPSLWSVSNGAVTPGSQAAAVSNGLGAQFFRGSPAHYTPLT 387

Query: 394 EDISCNTWPSMPSYSSCTVTT 414
             +S  +    P Y      T
Sbjct: 388 HPVSAPSSSGSPLYEGAAAAT 408


>gi|122937388 MAX gene associated [Homo sapiens]
          Length = 3114

 Score =  207 bits (528), Expect = 1e-53
 Identities = 106/191 (55%), Positives = 133/191 (69%), Gaps = 11/191 (5%)

Query: 53  GIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDH 112
           GI V L    +W +F+   TEMI+TK GRRMFP  +  +TGL+   KYIL+MDI P D+H
Sbjct: 74  GITVTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDNH 133

Query: 113 RYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHII 172
           RYK+    W  +GKAEP + GR+++HP+SP+TG +WM Q VSF KLKLTNN LD  GHII
Sbjct: 134 RYKWNGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHII 193

Query: 173 LNSMHKYQPRLHIVKAD------ENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLK 226
           L+SMH+Y PRLH+V A+      + NG G       T  FP+T F AVT+YQN +ITQLK
Sbjct: 194 LHSMHRYLPRLHLVPAEKAVEVIQLNGPGVH-----TFTFPQTEFFAVTAYQNIQITQLK 248

Query: 227 IENNPFAKGFR 237
           I+ NPFAKGFR
Sbjct: 249 IDYNPFAKGFR 259


>gi|7019549 T-box 21 [Homo sapiens]
          Length = 535

 Score =  200 bits (509), Expect = 2e-51
 Identities = 129/322 (40%), Positives = 171/322 (53%), Gaps = 37/322 (11%)

Query: 54  IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113
           ++V L+   LW KF++  TEMIITK GRRMFP     V GL P + Y + +D+V  D H 
Sbjct: 137 LRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHH 196

Query: 114 YKFADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFG 169
           +++   KW   GKAE +MPG RLYVHPDSP TGAHWMRQ VSF KLKLTNN     +   
Sbjct: 197 WRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQ 256

Query: 170 HIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHV--FPETAFIAVTSYQNHKITQLKI 227
            I+L S+HKYQPRLHIV+ ++     + N A  TH+  F ET FIAVT+YQN +ITQLKI
Sbjct: 257 MIVLQSLHKYQPRLHIVEVNDGEPEAACN-ASNTHIFTFQETQFIAVTAYQNAEITQLKI 315

Query: 228 ENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNL 287
           +NNPFAKGFR +       M        P  P    +     ++SP             L
Sbjct: 316 DNNPFAKGFREN----FESMYTSVDTSIPSPPGPNCQFLGGDHYSPL------------L 359

Query: 288 GSQYQCEN----GVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYM 343
            +QY   +     + G ++D++P       P++HS           E        K  ++
Sbjct: 360 PNQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSY----------EAEFRAVSMKPAFL 409

Query: 344 ETSPSEEDSFYRSSYPQQQGLG 365
            ++P    S+YR       G G
Sbjct: 410 PSAPGPTMSYYRGQEVLAPGAG 431


>gi|158187509 T-box 22 isoform 1 [Homo sapiens]
          Length = 520

 Score =  200 bits (509), Expect = 2e-51
 Identities = 123/301 (40%), Positives = 169/301 (56%), Gaps = 23/301 (7%)

Query: 14  PLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTE 73
           PLE   K  P  S   S  G+ S   +S ++   +     I++ L   ELW +FH++GTE
Sbjct: 57  PLEKQPKTEPSTSA-SSGCGSDSGYGNSSESLEEKD----IQMELQGSELWKRFHDIGTE 111

Query: 74  MIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-A 130
           MIITKAGRRMFPS +VKV GL+P  +Y + +D+VP D  RY++    ++W V G  +   
Sbjct: 112 MIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLC 171

Query: 131 MPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK--- 187
           +  R YVHPDSP +G  WMRQ++SF ++KLTNN +D  GHIIL SMHKY+PR+H+++   
Sbjct: 172 IIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGS 231

Query: 188 -ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHR 246
             D +           T  F ET F  VT+YQN +IT+LKIE NPFAKGFR  D      
Sbjct: 232 SVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR--DTGRNRG 289

Query: 247 MSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLP 306
           +     + YP  P  T+  K       F +++++ S+ S   S      G   P   LL 
Sbjct: 290 VLDGLLETYPWRPSFTLDFKT------FGADTQSGSSGS---SPVTSSGGAPSPLNSLLS 340

Query: 307 P 307
           P
Sbjct: 341 P 341


>gi|18375603 T-box 22 isoform 1 [Homo sapiens]
          Length = 520

 Score =  200 bits (509), Expect = 2e-51
 Identities = 123/301 (40%), Positives = 169/301 (56%), Gaps = 23/301 (7%)

Query: 14  PLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTE 73
           PLE   K  P  S   S  G+ S   +S ++   +     I++ L   ELW +FH++GTE
Sbjct: 57  PLEKQPKTEPSTSA-SSGCGSDSGYGNSSESLEEKD----IQMELQGSELWKRFHDIGTE 111

Query: 74  MIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-A 130
           MIITKAGRRMFPS +VKV GL+P  +Y + +D+VP D  RY++    ++W V G  +   
Sbjct: 112 MIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLC 171

Query: 131 MPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK--- 187
           +  R YVHPDSP +G  WMRQ++SF ++KLTNN +D  GHIIL SMHKY+PR+H+++   
Sbjct: 172 IIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGS 231

Query: 188 -ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHR 246
             D +           T  F ET F  VT+YQN +IT+LKIE NPFAKGFR  D      
Sbjct: 232 SVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR--DTGRNRG 289

Query: 247 MSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLP 306
           +     + YP  P  T+  K       F +++++ S+ S   S      G   P   LL 
Sbjct: 290 VLDGLLETYPWRPSFTLDFKT------FGADTQSGSSGS---SPVTSSGGAPSPLNSLLS 340

Query: 307 P 307
           P
Sbjct: 341 P 341


>gi|5730081 T-box, brain, 1 [Homo sapiens]
          Length = 682

 Score =  197 bits (500), Expect = 3e-50
 Identities = 107/209 (51%), Positives = 141/209 (67%), Gaps = 13/209 (6%)

Query: 43  QAAFTQQGMEGIK--VFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKY 100
           Q + TQ G+   K  V+L  R LWLKFH   TEMIITK GRRMFP     ++GL+P   Y
Sbjct: 191 QFSSTQPGLVPGKAQVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHY 250

Query: 101 ILLMDIVPADDHRYKFADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLK 159
            + +D++ AD + ++F   KW   GKA+  + G R+Y+HPDSP TGAHWMRQ +SF KLK
Sbjct: 251 NIFVDVILADPNHWRFQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLK 310

Query: 160 LTNNHLDPFGH---IILNSMHKYQPRLHIVKADENNGFGSKNTA----FCTHVFPETAFI 212
           LTNN      +   ++L S+HKYQPRLH+V+ +E+   G+++T+      T  FPET FI
Sbjct: 311 LTNNKGASNNNGQMVVLQSLHKYQPRLHVVEVNED---GTEDTSQPGRVQTFTFPETQFI 367

Query: 213 AVTSYQNHKITQLKIENNPFAKGFRGSDD 241
           AVT+YQN  ITQLKI++NPFAKGFR + D
Sbjct: 368 AVTAYQNTDITQLKIDHNPFAKGFRDNYD 396


>gi|4827024 T-box 19 [Homo sapiens]
          Length = 448

 Score =  194 bits (493), Expect = 2e-49
 Identities = 152/446 (34%), Positives = 204/446 (45%), Gaps = 57/446 (12%)

Query: 54  IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113
           +++ L +  LW +F EV  EMI+TK GRRMFP  K+ VTGL+P   Y LL+D VP D HR
Sbjct: 41  LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100

Query: 114 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 173
           +K+ + +W   GK E +    +Y+HPDSP  GAHWM+  +SF K+KLTN  L+  G I+L
Sbjct: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159

Query: 174 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233
           NS+HKY+P++HIV+       GS +       FPET FIAVT+YQN +IT LKI+ NPFA
Sbjct: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213

Query: 234 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 293
           K F       L    R   ++ P                   SES+ ++ S   G  +  
Sbjct: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250

Query: 294 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEED 351
            +GV  +G S      P P P P  H    H +  +         PY   YM  + S   
Sbjct: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHR----QAPYPSAYMHRNHSPSV 306

Query: 352 SFYRSSYPQQQGLGA--SYRTESAQRQACMYA------SSAPPSEPVPSLEDISCNT-WP 402
           +   SS    Q      S+ + S+   A + +         P   P P L  IS     P
Sbjct: 307 NLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGP 366

Query: 403 SMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV-----PRLAGMANHGSPQLGEGMFQH 457
           S P         V       +   +   TS P V     P  AG+   G P L       
Sbjct: 367 SGPG------PEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420

Query: 458 QTSVAHQPVVRQCGPQT-GLQSPGTL 482
            T+VA  P     GP   G  SP +L
Sbjct: 421 WTAVASHPFAGWGGPGAGGHHSPSSL 446


>gi|22538470 eomesodermin [Homo sapiens]
          Length = 686

 Score =  192 bits (487), Expect = 8e-49
 Identities = 127/327 (38%), Positives = 175/327 (53%), Gaps = 18/327 (5%)

Query: 56  VFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYK 115
           V+L  R LWLKFH   TEMIITK GRRMFP     + GLNP   Y + +++V AD + ++
Sbjct: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328

Query: 116 FADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFGHI 171
           F   KW   GKA+  M G ++YVHP+SP TG+HWMRQ +SF KLKLTNN   + +    I
Sbjct: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388

Query: 172 ILNSMHKYQPRLHIVKADENNGFGSKN--TAFCTHVFPETAFIAVTSYQNHKITQLKIEN 229
           +L S+HKYQPRLHIV+  E +G    N  +   T  F ET FIAVT+YQN  ITQLKI++
Sbjct: 389 VLQSLHKYQPRLHIVEVTE-DGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDH 447

Query: 230 NPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGS 289
           NPFAKGFR + D     +   +       P   V        + + +  R +  ++ L S
Sbjct: 448 NPFAKGFRDNYDSSHQIVPGGRYGVQSFFPEPFVN---TLPQARYYNGERTVPQTNGLLS 504

Query: 290 QYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSE 349
             Q E   + P + L+      P+ Q  +     +  + E  S+T  PY    +    S 
Sbjct: 505 PQQSEEVANPPQRWLVT-----PVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSH 559

Query: 350 EDSFYRS-SYPQQQGLG--ASYRTESA 373
              +Y   ++P   G G   SY+ + A
Sbjct: 560 ALGYYPDPTFPAMAGWGGRGSYQRKMA 586


>gi|158187511 T-box 22 isoform 2 [Homo sapiens]
          Length = 400

 Score =  159 bits (401), Expect = 8e-39
 Identities = 94/232 (40%), Positives = 130/232 (56%), Gaps = 18/232 (7%)

Query: 83  MFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-AMPGRLYVHP 139
           MFPS +VKV GL+P  +Y + +D+VP D  RY++    ++W V G  +   +  R YVHP
Sbjct: 1   MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 60

Query: 140 DSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK----ADENNGFG 195
           DSP +G  WMRQ++SF ++KLTNN +D  GHIIL SMHKY+PR+H+++     D +    
Sbjct: 61  DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 120

Query: 196 SKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEY 255
                  T  F ET F  VT+YQN +IT+LKIE NPFAKGFR  D      +     + Y
Sbjct: 121 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR--DTGRNRGVLDGLLETY 178

Query: 256 PVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLPP 307
           P  P  T+  K       F +++++ S+ S   S      G   P   LL P
Sbjct: 179 PWRPSFTLDFKT------FGADTQSGSSGS---SPVTSSGGAPSPLNSLLSP 221


>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
            sapiens]
          Length = 1562

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 50/219 (22%), Positives = 83/219 (37%), Gaps = 25/219 (11%)

Query: 227  IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 286
            +E N   K +R +D +             P +P +    +  +    ++S  R  STS +
Sbjct: 1028 VEQNKLNKDYRANDTVP------------PTIPYNQSYDQ--NTGGSYNSSDRGSSTSGS 1073

Query: 287  LGSQYQCENGVSGPSQ------DLLPPPNPYPLPQEHSQIYHCT-KRKEEECSTTDHPYK 339
             G +         P Q      DLLPPP  +P P  +S+ Y+ +     ++      P  
Sbjct: 1074 QGHKKGARTP-KVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPA 1132

Query: 340  KPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCN 399
            + Y++    EE+   R   P  +G  +S    S   Q+    + +P  E  P L+D    
Sbjct: 1133 RTYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEE 1192

Query: 400  T--WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV 436
            T      P      V+   P   +   H +  + SGPLV
Sbjct: 1193 TGHMQHQPDRRRQPVSPPPPPRPISPPH-TYGYISGPLV 1230


>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
            sapiens]
          Length = 1615

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 50/219 (22%), Positives = 83/219 (37%), Gaps = 25/219 (11%)

Query: 227  IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 286
            +E N   K +R +D +             P +P +    +  +    ++S  R  STS +
Sbjct: 1081 VEQNKLNKDYRANDTVP------------PTIPYNQSYDQ--NTGGSYNSSDRGSSTSGS 1126

Query: 287  LGSQYQCENGVSGPSQ------DLLPPPNPYPLPQEHSQIYHCT-KRKEEECSTTDHPYK 339
             G +         P Q      DLLPPP  +P P  +S+ Y+ +     ++      P  
Sbjct: 1127 QGHKKGARTP-KVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPA 1185

Query: 340  KPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCN 399
            + Y++    EE+   R   P  +G  +S    S   Q+    + +P  E  P L+D    
Sbjct: 1186 RTYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEE 1245

Query: 400  T--WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV 436
            T      P      V+   P   +   H +  + SGPLV
Sbjct: 1246 TGHMQHQPDRRRQPVSPPPPPRPISPPH-TYGYISGPLV 1283


>gi|224994173 roundabout 1 isoform d [Homo sapiens]
          Length = 1551

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 50/219 (22%), Positives = 83/219 (37%), Gaps = 25/219 (11%)

Query: 227  IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 286
            +E N   K +R +D +             P +P +    +  +    ++S  R  STS +
Sbjct: 1017 VEQNKLNKDYRANDTVP------------PTIPYNQSYDQ--NTGGSYNSSDRGSSTSGS 1062

Query: 287  LGSQYQCENGVSGPSQ------DLLPPPNPYPLPQEHSQIYHCT-KRKEEECSTTDHPYK 339
             G +         P Q      DLLPPP  +P P  +S+ Y+ +     ++      P  
Sbjct: 1063 QGHKKGARTP-KVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPA 1121

Query: 340  KPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCN 399
            + Y++    EE+   R   P  +G  +S    S   Q+    + +P  E  P L+D    
Sbjct: 1122 RMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEE 1181

Query: 400  T--WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV 436
            T      P      V+   P   +   H +  + SGPLV
Sbjct: 1182 TGHMQHQPDRRRQPVSPPPPPRPISPPH-TYGYISGPLV 1219


>gi|224994171 roundabout 1 isoform c [Homo sapiens]
          Length = 1606

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 50/219 (22%), Positives = 83/219 (37%), Gaps = 25/219 (11%)

Query: 227  IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 286
            +E N   K +R +D +             P +P +    +  +    ++S  R  STS +
Sbjct: 1072 VEQNKLNKDYRANDTVP------------PTIPYNQSYDQ--NTGGSYNSSDRGSSTSGS 1117

Query: 287  LGSQYQCENGVSGPSQ------DLLPPPNPYPLPQEHSQIYHCT-KRKEEECSTTDHPYK 339
             G +         P Q      DLLPPP  +P P  +S+ Y+ +     ++      P  
Sbjct: 1118 QGHKKGARTP-KVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPA 1176

Query: 340  KPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCN 399
            + Y++    EE+   R   P  +G  +S    S   Q+    + +P  E  P L+D    
Sbjct: 1177 RMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEE 1236

Query: 400  T--WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV 436
            T      P      V+   P   +   H +  + SGPLV
Sbjct: 1237 TGHMQHQPDRRRQPVSPPPPPRPISPPH-TYGYISGPLV 1274


>gi|19743806 roundabout 1 isoform b [Homo sapiens]
          Length = 1612

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 50/219 (22%), Positives = 83/219 (37%), Gaps = 25/219 (11%)

Query: 227  IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 286
            +E N   K +R +D +             P +P +    +  +    ++S  R  STS +
Sbjct: 1078 VEQNKLNKDYRANDTVP------------PTIPYNQSYDQ--NTGGSYNSSDRGSSTSGS 1123

Query: 287  LGSQYQCENGVSGPSQ------DLLPPPNPYPLPQEHSQIYHCT-KRKEEECSTTDHPYK 339
             G +         P Q      DLLPPP  +P P  +S+ Y+ +     ++      P  
Sbjct: 1124 QGHKKGARTP-KVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPA 1182

Query: 340  KPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCN 399
            + Y++    EE+   R   P  +G  +S    S   Q+    + +P  E  P L+D    
Sbjct: 1183 RMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEE 1242

Query: 400  T--WPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV 436
            T      P      V+   P   +   H +  + SGPLV
Sbjct: 1243 TGHMQHQPDRRRQPVSPPPPPRPISPPH-TYGYISGPLV 1280


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,799,435
Number of Sequences: 37866
Number of extensions: 1237490
Number of successful extensions: 5066
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 4874
Number of HSP's gapped (non-prelim): 230
length of query: 518
length of database: 18,247,518
effective HSP length: 107
effective length of query: 411
effective length of database: 14,195,856
effective search space: 5834496816
effective search space used: 5834496816
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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