Guide to the Human Genome
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Search of human proteins with 31559821

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo
sapiens]
         (279 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]     573   e-164
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]          180   1e-45
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]          180   1e-45
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]          180   1e-45
gi|239508957 PREDICTED: similar to hCG1770601 [Homo sapiens]          180   1e-45
gi|122939172 connexin 45 [Homo sapiens]                               178   5e-45
gi|69122473 connexin 45 [Homo sapiens]                                178   5e-45
gi|22779877 connexin 46 [Homo sapiens]                                150   9e-37
gi|55953076 connexin 50 [Homo sapiens]                                147   1e-35
gi|14211941 gap junction protein, alpha 10 [Homo sapiens]             143   1e-34
gi|62865885 connexin 37 [Homo sapiens]                                141   7e-34
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]       140   1e-33
gi|4504001 connexin 43 [Homo sapiens]                                 136   2e-32
gi|32483412 connexin 40 [Homo sapiens]                                135   3e-32
gi|6631083 connexin 40 [Homo sapiens]                                 135   3e-32
gi|42558283 gap junction protein beta 2 [Homo sapiens]                132   3e-31
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]       132   3e-31
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]    129   4e-30
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]        128   6e-30
gi|159032020 gap junction protein, beta 6 [Homo sapiens]              127   1e-29
gi|158966714 gap junction protein, beta 6 [Homo sapiens]              127   1e-29
gi|158966717 gap junction protein, beta 6 [Homo sapiens]              127   1e-29
gi|40254837 gap junction protein, beta 6 [Homo sapiens]               127   1e-29
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]       126   2e-29
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]         126   2e-29
gi|145699105 connexin40.1 [Homo sapiens]                              122   3e-28
gi|54607056 connexin 31 [Homo sapiens]                                118   7e-27
gi|13128960 connexin 31 [Homo sapiens]                                118   7e-27
gi|23397464 gap junction protein, beta 4 [Homo sapiens]               116   2e-26
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]      111   8e-25

>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
          Length = 279

 Score =  573 bits (1478), Expect = e-164
 Identities = 279/279 (100%), Positives = 279/279 (100%)

Query: 1   MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC 60
           MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC
Sbjct: 1   MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC 60

Query: 61  KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGRE 120
           KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGRE
Sbjct: 61  KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGRE 120

Query: 121 GNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITC 180
           GNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITC
Sbjct: 121 GNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITC 180

Query: 181 NLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSESTRR 240
           NLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSESTRR
Sbjct: 181 NLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSESTRR 240

Query: 241 HKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA 279
           HKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA
Sbjct: 241 HKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA 279


>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score =  180 bits (456), Expect = 1e-45
 Identities = 89/96 (92%), Positives = 90/96 (93%), Gaps = 1/96 (1%)

Query: 1   MCGRFLRR-LLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 59
           MCGRFLR  LLAEES  STPVGRLL PVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG
Sbjct: 19  MCGRFLRWWLLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 78

Query: 60  CKAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFT 95
           CKAACFDAFHPLSPLRFWVFQVILVAVPS LYMG+T
Sbjct: 79  CKAACFDAFHPLSPLRFWVFQVILVAVPSVLYMGYT 114


>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score =  180 bits (456), Expect = 1e-45
 Identities = 89/96 (92%), Positives = 90/96 (93%), Gaps = 1/96 (1%)

Query: 1   MCGRFLRR-LLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 59
           MCGRFLR  LLAEES  STPVGRLL PVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG
Sbjct: 19  MCGRFLRWWLLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 78

Query: 60  CKAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFT 95
           CKAACFDAFHPLSPLRFWVFQVILVAVPS LYMG+T
Sbjct: 79  CKAACFDAFHPLSPLRFWVFQVILVAVPSVLYMGYT 114


>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score =  180 bits (456), Expect = 1e-45
 Identities = 89/96 (92%), Positives = 90/96 (93%), Gaps = 1/96 (1%)

Query: 1   MCGRFLRR-LLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 59
           MCGRFLR  LLAEES  STPVGRLL PVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG
Sbjct: 19  MCGRFLRWWLLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 78

Query: 60  CKAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFT 95
           CKAACFDAFHPLSPLRFWVFQVILVAVPS LYMG+T
Sbjct: 79  CKAACFDAFHPLSPLRFWVFQVILVAVPSVLYMGYT 114


>gi|239508957 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score =  180 bits (456), Expect = 1e-45
 Identities = 89/96 (92%), Positives = 90/96 (93%), Gaps = 1/96 (1%)

Query: 1   MCGRFLRR-LLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 59
           MCGRFLR  LLAEES  STPVGRLL PVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG
Sbjct: 19  MCGRFLRWWLLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 78

Query: 60  CKAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFT 95
           CKAACFDAFHPLSPLRFWVFQVILVAVPS LYMG+T
Sbjct: 79  CKAACFDAFHPLSPLRFWVFQVILVAVPSVLYMGYT 114


>gi|122939172 connexin 45 [Homo sapiens]
          Length = 396

 Score =  178 bits (451), Expect = 5e-45
 Identities = 107/256 (41%), Positives = 139/256 (54%), Gaps = 40/256 (15%)

Query: 1   MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC 60
           M   FL RLL E    ST VG++ L VL+ FR+VL A  G  +Y DEQS+FVC+T+QPGC
Sbjct: 1   MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60

Query: 61  KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHV--IWHWELSGKG--------- 109
           +  C+DAF PLS +RFWVFQ+ILVA PS +Y+G+ ++ +  + H E   K          
Sbjct: 61  ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120

Query: 110 -KEEETLIQGREGNTDVP-------------------------GAGSLR---LLWAYVAQ 140
            K+   L +  E N + P                         G   +R   L+  YV Q
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180

Query: 141 LGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITCNLSRPSEKTIFLKTMFGVSG 200
           L AR V E   L  QY LYGFQ+   + C R PC   I C +SRP+EKTIFL  M+GV+G
Sbjct: 181 LLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTG 240

Query: 201 FCLLFTFLELVLLGLG 216
            CLL    E++ LG G
Sbjct: 241 LCLLLNIWEMLHLGFG 256


>gi|69122473 connexin 45 [Homo sapiens]
          Length = 396

 Score =  178 bits (451), Expect = 5e-45
 Identities = 107/256 (41%), Positives = 139/256 (54%), Gaps = 40/256 (15%)

Query: 1   MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC 60
           M   FL RLL E    ST VG++ L VL+ FR+VL A  G  +Y DEQS+FVC+T+QPGC
Sbjct: 1   MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60

Query: 61  KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHV--IWHWELSGKG--------- 109
           +  C+DAF PLS +RFWVFQ+ILVA PS +Y+G+ ++ +  + H E   K          
Sbjct: 61  ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120

Query: 110 -KEEETLIQGREGNTDVP-------------------------GAGSLR---LLWAYVAQ 140
            K+   L +  E N + P                         G   +R   L+  YV Q
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180

Query: 141 LGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITCNLSRPSEKTIFLKTMFGVSG 200
           L AR V E   L  QY LYGFQ+   + C R PC   I C +SRP+EKTIFL  M+GV+G
Sbjct: 181 LLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTG 240

Query: 201 FCLLFTFLELVLLGLG 216
            CLL    E++ LG G
Sbjct: 241 LCLLLNIWEMLHLGFG 256


>gi|22779877 connexin 46 [Homo sapiens]
          Length = 435

 Score =  150 bits (380), Expect = 9e-37
 Identities = 89/236 (37%), Positives = 132/236 (55%), Gaps = 17/236 (7%)

Query: 5   FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
           FL RLL      ST +G++ L VL  FR+++L A+   V+GDEQS+F C+TQQPGC+  C
Sbjct: 6   FLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPGCENVC 65

Query: 65  FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQ----GRE 120
           +D   P+S +RFW  Q+I V+ P+ +Y+G  L H++   E   + +EEE L +     +E
Sbjct: 66  YDRAFPISHIRFWALQIIFVSTPTLIYLGHVL-HIVRMEEKKKEREEEEQLKRESPSPKE 124

Query: 121 GNTDVPGA----GSLR----LLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRRE 172
              D P +    G +R    LL  YV  +  + + E   +  QY LYGF++   + C R 
Sbjct: 125 PPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYRCDRW 184

Query: 173 PCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSS 228
           PC  ++ C +SRP+EKTIF+  M  V+   LL   LE+  LG    W+  K   +S
Sbjct: 185 PCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLG----WKKLKQGVTS 236


>gi|55953076 connexin 50 [Homo sapiens]
          Length = 433

 Score =  147 bits (371), Expect = 1e-35
 Identities = 84/227 (37%), Positives = 124/227 (54%), Gaps = 19/227 (8%)

Query: 5   FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
           FL  +L E +  ST +GR+ L VL  FR+++L  +   V+GDEQS+FVC+TQQPGC+  C
Sbjct: 6   FLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVC 65

Query: 65  FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREGNTD 124
           +D   P+S +R WV Q+I V+ PS +Y+G  +++V    E   K +E E L Q + G   
Sbjct: 66  YDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV--RMEEKRKSREAEELGQ-QAGTNG 122

Query: 125 VPGAGSLR----------------LLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFA 168
            P  GS++                LL  Y+  +  + + E   +   Y LYGF++   + 
Sbjct: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPLYR 182

Query: 169 CRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGL 215
           C R PC   + C +SRP+EKTIF+  M  V+   L    +EL  LGL
Sbjct: 183 CSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGL 229


>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
          Length = 543

 Score =  143 bits (361), Expect = 1e-34
 Identities = 90/241 (37%), Positives = 126/241 (52%), Gaps = 23/241 (9%)

Query: 9   LLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 68
           +L E    ST VG++ L +L  FR+++L  +   V+ DEQS F C+T+QPGC   C+D  
Sbjct: 10  ILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNNICYDDA 69

Query: 69  HPLSPLRFWVFQVILVAVPSALYMGFTLY--------------HVIWHWELSGKGKEEET 114
            P+S +RFWV Q+I V+ PS +YMG  LY              H+    E      EE+ 
Sbjct: 70  FPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPDLDLEEQQ 129

Query: 115 LI-------QGREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSF 167
            I       + ++    VP  G   LL  YV  +  R VLE   +  QY LYGFQM   +
Sbjct: 130 RIDRELRRLEEQKRIHKVPLKGC--LLRTYVLHILTRSVLEVGFMIGQYILYGFQMHPLY 187

Query: 168 ACRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSS 227
            C + PC  ++ C +SRP+EKTIF+  M  ++   LL   LE+  LG+ +  RT   KSS
Sbjct: 188 KCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRTLYKKSS 247

Query: 228 S 228
           S
Sbjct: 248 S 248


>gi|62865885 connexin 37 [Homo sapiens]
          Length = 333

 Score =  141 bits (355), Expect = 7e-34
 Identities = 84/226 (37%), Positives = 119/226 (52%), Gaps = 17/226 (7%)

Query: 5   FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
           FL +LL +    ST VG++ L VL  FR+++L  +G  V+GDEQS+F C+T QPGC   C
Sbjct: 6   FLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVC 65

Query: 65  FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETL--------- 115
           +D   P+S +R+WV Q + V+ P+ +Y+G  +Y       L  K  E   L         
Sbjct: 66  YDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQVER 125

Query: 116 ----IQGREGNTDVPGAGSLR----LLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSF 167
               ++ +     V   G LR    L+  YVA +  + VLE   L  Q+ LYG+ M   F
Sbjct: 126 ALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVF 185

Query: 168 ACRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
            C+R PC   + C +SRP+EKTIF+  M  V    L+   LELV L
Sbjct: 186 VCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHL 231


>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
          Length = 321

 Score =  140 bits (353), Expect = 1e-33
 Identities = 94/279 (33%), Positives = 133/279 (47%), Gaps = 65/279 (23%)

Query: 6   LRRLL-AEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
           L RLL A   + ST +GR+LL V++ FR++++A  G  VY DEQ+ FVC+T QPGC  AC
Sbjct: 7   LERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQAC 66

Query: 65  FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWEL------------------- 105
           +D   P+S +R+WVFQ+I+V  PS  ++ ++++      E                    
Sbjct: 67  YDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDPPESIGG 126

Query: 106 --------SGKGKEEE-----TLIQGREGNTD----------------VPGAGSLR---- 132
                   SG GK E+      ++ G   NT+                 P    LR    
Sbjct: 127 PGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSGLRTASK 186

Query: 133 --------LLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITCNLSR 184
                   +   Y+ Q+  R  LE   L  QY LYGF +P  + C R PC+  + C +SR
Sbjct: 187 SKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEVECYVSR 246

Query: 185 PSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWK 223
           P+EKT+FL  MF VSG C++    EL  LG    WR  K
Sbjct: 247 PTEKTVFLVFMFAVSGICVVLNLAELNHLG----WRKIK 281


>gi|4504001 connexin 43 [Homo sapiens]
          Length = 382

 Score =  136 bits (343), Expect = 2e-32
 Identities = 82/224 (36%), Positives = 121/224 (54%), Gaps = 21/224 (9%)

Query: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
           L +LL +    ST  G++ L VL  FR++LL  +    +GDEQS F C+TQQPGC+  C+
Sbjct: 7   LGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCY 66

Query: 66  DAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREG-NTD 124
           D   P+S +RFWV Q+I V+VP+ LY+    Y  +   E     KEEE  +   +G N D
Sbjct: 67  DKSFPISHVRFWVLQIIFVSVPTLLYLAHVFY--VMRKEEKLNKKEEELKVAQTDGVNVD 124

Query: 125 V----------------PGAGSLR--LLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSS 166
           +                 G   +R  LL  Y+  +  + + E A L +Q+++YGF + + 
Sbjct: 125 MHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFSLSAV 184

Query: 167 FACRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLEL 210
           + C+R+PC   + C LSRP+EKTIF+  M  VS   L    +EL
Sbjct: 185 YTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIEL 228


>gi|32483412 connexin 40 [Homo sapiens]
          Length = 358

 Score =  135 bits (341), Expect = 3e-32
 Identities = 78/225 (34%), Positives = 116/225 (51%), Gaps = 15/225 (6%)

Query: 5   FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
           FL   L E  + ST VG++ L VL  FR+++L  +    +GDEQ++F C T QPGC+  C
Sbjct: 6   FLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVC 65

Query: 65  FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWH-----------WELSGKGKEEE 113
           +D   P+S +R+WV Q+I V+ PS +YMG  ++ V               E+ G G  E 
Sbjct: 66  YDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGSYEY 125

Query: 114 TLIQGREGNTDVPGAGSL----RLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFAC 169
            + +  E +    G G +     LL  YV  +  R  +E   +  QY +YG  + +   C
Sbjct: 126 PVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVC 185

Query: 170 RREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLG 214
           RR PC   + C +SRP+EK +F+  M  V+   LL +  EL  LG
Sbjct: 186 RRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLG 230


>gi|6631083 connexin 40 [Homo sapiens]
          Length = 358

 Score =  135 bits (341), Expect = 3e-32
 Identities = 78/225 (34%), Positives = 116/225 (51%), Gaps = 15/225 (6%)

Query: 5   FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
           FL   L E  + ST VG++ L VL  FR+++L  +    +GDEQ++F C T QPGC+  C
Sbjct: 6   FLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVC 65

Query: 65  FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWH-----------WELSGKGKEEE 113
           +D   P+S +R+WV Q+I V+ PS +YMG  ++ V               E+ G G  E 
Sbjct: 66  YDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGSYEY 125

Query: 114 TLIQGREGNTDVPGAGSL----RLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFAC 169
            + +  E +    G G +     LL  YV  +  R  +E   +  QY +YG  + +   C
Sbjct: 126 PVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVC 185

Query: 170 RREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLG 214
           RR PC   + C +SRP+EK +F+  M  V+   LL +  EL  LG
Sbjct: 186 RRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLG 230


>gi|42558283 gap junction protein beta 2 [Homo sapiens]
          Length = 226

 Score =  132 bits (332), Expect = 3e-31
 Identities = 73/212 (34%), Positives = 116/212 (54%), Gaps = 8/212 (3%)

Query: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
           L+ +L   ++ ST +G++ L VL  FR+++L  +   V+GDEQ++FVC+T QPGCK  C+
Sbjct: 6   LQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCY 65

Query: 66  DAFHPLSPLRFWVFQVILVAVPSALYMGFTLY--HVIWHWELSGKGKEE-ETLIQGREGN 122
           D + P+S +R W  Q+I V+ P+ L      Y  H      + G+ K E + + + +   
Sbjct: 66  DHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIEEIKTQK 125

Query: 123 TDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181
             + G+    L W Y + +  R++ E A + + Y +Y GF M     C   PC  ++ C 
Sbjct: 126 VRIEGS----LWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCF 181

Query: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
           +SRP+EKT+F   M  VSG C+L    EL  L
Sbjct: 182 VSRPTEKTVFTVFMIAVSGICILLNVTELCYL 213


>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
          Length = 515

 Score =  132 bits (332), Expect = 3e-31
 Identities = 82/247 (33%), Positives = 120/247 (48%), Gaps = 27/247 (10%)

Query: 10  LAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 69
           L E    ST +G++ L +L  FR+++L  +   V+ DEQS F+C+T+QPGC+  C+D   
Sbjct: 11  LEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNVCYDQAF 70

Query: 70  PLSPLRFWVFQVILVAVPSALYMGFTLYH---------------------VIWHWELSGK 108
           P+S +R+WV QVI V+ PS +YMG  LY                      V +      +
Sbjct: 71  PISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVEFEMPRDRR 130

Query: 109 GKEEETLIQGREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFA 168
             E+E     +      P  G+L  L  YV  +  R V+E   +  QY LYGF +   F 
Sbjct: 131 RLEQELCQLEKRKLNKAPLRGTL--LCTYVIHIFTRSVVEVGFMIGQYLLYGFHLEPLFK 188

Query: 169 CRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGR----WWRTWKH 224
           C   PC   I C +SRP+EKTIFL  M  ++   L    LE+  LG  +     W  +K 
Sbjct: 189 CHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKRGLWGKYKL 248

Query: 225 KSSSSKY 231
           K   +++
Sbjct: 249 KKEHNEF 255


>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
          Length = 294

 Score =  129 bits (323), Expect = 4e-30
 Identities = 86/252 (34%), Positives = 127/252 (50%), Gaps = 25/252 (9%)

Query: 5   FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
           FL  LL     +S  VGRL L V+L FR+++LA  G  V+ DEQ EFVC+T QPGC+  C
Sbjct: 6   FLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTC 65

Query: 65  FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKE---EETLIQGREG 121
           +D   P+S  RFW+F ++L++ P  L++ ++++           GKE    E   Q   G
Sbjct: 66  YDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRA---------GKEAGGAEAAAQCAPG 116

Query: 122 NTDVPGA----GSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGS 177
             +   A     + R    Y+  +  RL+ E   LG Q  LYGF++   FAC   PC  +
Sbjct: 117 LPEAQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHT 176

Query: 178 ITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSES 237
           + C +SRP+EKT+F+   F V     L +  EL  L        WK +  + +    +  
Sbjct: 177 VDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHL-------LWKGRPRAGE--RDNRC 227

Query: 238 TRRHKKATDSLP 249
            R H++A   LP
Sbjct: 228 NRAHEEAQKLLP 239


>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
          Length = 223

 Score =  128 bits (321), Expect = 6e-30
 Identities = 79/216 (36%), Positives = 118/216 (54%), Gaps = 14/216 (6%)

Query: 1   MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGC 60
           M   FLR LL+  ++ ST  G + L V+  FRL++   +   V+ DEQ EF C+++QPGC
Sbjct: 1   MSWMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGC 60

Query: 61  KAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGRE 120
           K  CFD F P+S +R W  Q+I+V+ PS L     + HV +H     +G+E+    + R+
Sbjct: 61  KNVCFDDFFPISQVRLWALQLIMVSTPSLL----VVLHVAYH-----EGREK----RHRK 107

Query: 121 GNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSIT 179
                PG     L +AY+  L  +   E   L L Y LY GF +P    C  +PC  ++ 
Sbjct: 108 KLYVSPGTMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKCDLKPCPNTVD 167

Query: 180 CNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGL 215
           C +S+P+EKTIF+  +   S  C++  F+EL  L L
Sbjct: 168 CFISKPTEKTIFILFLVITSCLCIVLNFIELSFLVL 203


>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  127 bits (318), Expect = 1e-29
 Identities = 68/230 (29%), Positives = 119/230 (51%), Gaps = 8/230 (3%)

Query: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
           L   +   ++ ST +G++ + V+  FR+++L  +   V+GDEQ +FVC+T QPGCK  C+
Sbjct: 6   LHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCY 65

Query: 66  DAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQGREGN 122
           D F P+S +R W  Q+I V+ P+   A+++ +  +     +    K  + + +   ++  
Sbjct: 66  DHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIEDIKKQK 125

Query: 123 TDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181
             + G+    L W Y + +  R++ E A + + Y LY G+ +P    C  +PC   + C 
Sbjct: 126 VRIEGS----LWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCF 181

Query: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKY 231
           +SRP+EKT+F   M   S  C+L    EL  L L   +R  K   +   +
Sbjct: 182 ISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNH 231


>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  127 bits (318), Expect = 1e-29
 Identities = 68/230 (29%), Positives = 119/230 (51%), Gaps = 8/230 (3%)

Query: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
           L   +   ++ ST +G++ + V+  FR+++L  +   V+GDEQ +FVC+T QPGCK  C+
Sbjct: 6   LHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCY 65

Query: 66  DAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQGREGN 122
           D F P+S +R W  Q+I V+ P+   A+++ +  +     +    K  + + +   ++  
Sbjct: 66  DHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIEDIKKQK 125

Query: 123 TDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181
             + G+    L W Y + +  R++ E A + + Y LY G+ +P    C  +PC   + C 
Sbjct: 126 VRIEGS----LWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCF 181

Query: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKY 231
           +SRP+EKT+F   M   S  C+L    EL  L L   +R  K   +   +
Sbjct: 182 ISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNH 231


>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  127 bits (318), Expect = 1e-29
 Identities = 68/230 (29%), Positives = 119/230 (51%), Gaps = 8/230 (3%)

Query: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
           L   +   ++ ST +G++ + V+  FR+++L  +   V+GDEQ +FVC+T QPGCK  C+
Sbjct: 6   LHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCY 65

Query: 66  DAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQGREGN 122
           D F P+S +R W  Q+I V+ P+   A+++ +  +     +    K  + + +   ++  
Sbjct: 66  DHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIEDIKKQK 125

Query: 123 TDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181
             + G+    L W Y + +  R++ E A + + Y LY G+ +P    C  +PC   + C 
Sbjct: 126 VRIEGS----LWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCF 181

Query: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKY 231
           +SRP+EKT+F   M   S  C+L    EL  L L   +R  K   +   +
Sbjct: 182 ISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNH 231


>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  127 bits (318), Expect = 1e-29
 Identities = 68/230 (29%), Positives = 119/230 (51%), Gaps = 8/230 (3%)

Query: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
           L   +   ++ ST +G++ + V+  FR+++L  +   V+GDEQ +FVC+T QPGCK  C+
Sbjct: 6   LHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCY 65

Query: 66  DAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQGREGN 122
           D F P+S +R W  Q+I V+ P+   A+++ +  +     +    K  + + +   ++  
Sbjct: 66  DHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIEDIKKQK 125

Query: 123 TDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181
             + G+    L W Y + +  R++ E A + + Y LY G+ +P    C  +PC   + C 
Sbjct: 126 VRIEGS----LWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCF 181

Query: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKY 231
           +SRP+EKT+F   M   S  C+L    EL  L L   +R  K   +   +
Sbjct: 182 ISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNH 231


>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  126 bits (317), Expect = 2e-29
 Identities = 73/212 (34%), Positives = 114/212 (53%), Gaps = 9/212 (4%)

Query: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
           L  LL+  +R ST +GR+ L V+  FR+++L  +   V+GDE+S F+C+T QPGC + C+
Sbjct: 6   LYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCY 65

Query: 66  DAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQGREGN 122
           D F P+S +R W  Q+ILV+ P+   A+++    +       L G G +   L + +   
Sbjct: 66  DQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHG-DPLHLEEVKRHK 124

Query: 123 TDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181
             + G     L W YV  +  RL+ E   + + Y LY G+ M     C   PC  ++ C 
Sbjct: 125 VHISGT----LWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180

Query: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
           +SRP+EKT+F   M   SG C++    E+V L
Sbjct: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212


>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  126 bits (317), Expect = 2e-29
 Identities = 73/212 (34%), Positives = 114/212 (53%), Gaps = 9/212 (4%)

Query: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
           L  LL+  +R ST +GR+ L V+  FR+++L  +   V+GDE+S F+C+T QPGC + C+
Sbjct: 6   LYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCY 65

Query: 66  DAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQGREGN 122
           D F P+S +R W  Q+ILV+ P+   A+++    +       L G G +   L + +   
Sbjct: 66  DQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHG-DPLHLEEVKRHK 124

Query: 123 TDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181
             + G     L W YV  +  RL+ E   + + Y LY G+ M     C   PC  ++ C 
Sbjct: 125 VHISGT----LWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180

Query: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
           +SRP+EKT+F   M   SG C++    E+V L
Sbjct: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212


>gi|145699105 connexin40.1 [Homo sapiens]
          Length = 370

 Score =  122 bits (306), Expect = 3e-28
 Identities = 69/204 (33%), Positives = 101/204 (49%), Gaps = 15/204 (7%)

Query: 18  TPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLRFW 77
           T VG+L   + +  R++++  +G  VY DEQ  FVC+T QPGC   C+D F P+S LRFW
Sbjct: 19  TMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVSHLRFW 78

Query: 78  VFQVILVAVPSALYMGFTLYHVIWHWELS----------GKGKEEETLIQGREGNTDVPG 127
           + Q + V +PSA++  + L+       L             G+       G  G   VP 
Sbjct: 79  LIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPRPFGERGGLQVPD 138

Query: 128 AGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITCNLSRPSE 187
             +      Y+  L  R +LE A   L Y L+GF  P  F C R PC G + C +SRP+E
Sbjct: 139 FSA-----GYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPCTGVVDCYVSRPTE 193

Query: 188 KTIFLKTMFGVSGFCLLFTFLELV 211
           K++ +  ++ VS    L    +LV
Sbjct: 194 KSLLMLFLWAVSALSFLLGLADLV 217


>gi|54607056 connexin 31 [Homo sapiens]
          Length = 270

 Score =  118 bits (295), Expect = 7e-27
 Identities = 72/212 (33%), Positives = 110/212 (51%), Gaps = 12/212 (5%)

Query: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
           L+ LL+  ++ ST  GR+ L V+  FR+++   +   V+GDEQ +F C+T+QPGC   C+
Sbjct: 6   LQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCY 65

Query: 66  DAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREGNTDV 125
           D + P+S +R W  Q+I V  PS L     + HV +  E   + +++     G +     
Sbjct: 66  DNYFPISNIRLWALQLIFVTCPSLL----VILHVAYREERERRHRQK----HGDQCAKLY 117

Query: 126 PGAGSLR--LLWAYVAQLGARLVLEGAALGLQYHL-YGFQMPSSFACRR-EPCLGSITCN 181
             AG     L W Y+  L  +L++E   L L + L +GF MP    C    PC   + C 
Sbjct: 118 DNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCY 177

Query: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
           ++RP+EK IF   M G S  C++ T  EL  L
Sbjct: 178 IARPTEKKIFTYFMVGASAVCIVLTICELCYL 209


>gi|13128960 connexin 31 [Homo sapiens]
          Length = 270

 Score =  118 bits (295), Expect = 7e-27
 Identities = 72/212 (33%), Positives = 110/212 (51%), Gaps = 12/212 (5%)

Query: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
           L+ LL+  ++ ST  GR+ L V+  FR+++   +   V+GDEQ +F C+T+QPGC   C+
Sbjct: 6   LQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCY 65

Query: 66  DAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREGNTDV 125
           D + P+S +R W  Q+I V  PS L     + HV +  E   + +++     G +     
Sbjct: 66  DNYFPISNIRLWALQLIFVTCPSLL----VILHVAYREERERRHRQK----HGDQCAKLY 117

Query: 126 PGAGSLR--LLWAYVAQLGARLVLEGAALGLQYHL-YGFQMPSSFACRR-EPCLGSITCN 181
             AG     L W Y+  L  +L++E   L L + L +GF MP    C    PC   + C 
Sbjct: 118 DNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCY 177

Query: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
           ++RP+EK IF   M G S  C++ T  EL  L
Sbjct: 178 IARPTEKKIFTYFMVGASAVCIVLTICELCYL 209


>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
          Length = 266

 Score =  116 bits (291), Expect = 2e-26
 Identities = 68/212 (32%), Positives = 107/212 (50%), Gaps = 11/212 (5%)

Query: 5   FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
           FL+ LL+  ++ ST + R+ L V+  FR+++   +   V+ DEQ +FVC+T+QPGC   C
Sbjct: 5   FLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPNVC 64

Query: 65  FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREGNTD 124
           +D F P+S +R W  Q+ILV  PS L        V+ H     + + +  L  G    + 
Sbjct: 65  YDEFFPVSHVRLWALQLILVTCPSLL--------VVMHVAYREERERKHHLKHGPNAPSL 116

Query: 125 VPGAGSLR--LLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181
                  R  L W Y+  L  +  ++   L + + LY  + MP   AC  EPC  ++ C 
Sbjct: 117 YDNLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCY 176

Query: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
           +SRP+EK +F   M   +  C+L    E+  L
Sbjct: 177 ISRPTEKKVFTYFMVTTAAICILLNLSEVFYL 208


>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
          Length = 273

 Score =  111 bits (277), Expect = 8e-25
 Identities = 65/209 (31%), Positives = 103/209 (49%), Gaps = 13/209 (6%)

Query: 9   LLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 68
           LL+  ++ ST  GR+ L ++  FR+++   +   V+ D+  +F C+T+QPGC   CFD F
Sbjct: 9   LLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCSNVCFDEF 68

Query: 69  HPLSPLRFWVFQVILVAVPSALYMGFTLYHVIW---HWELSGKGKEEETLIQGREGNTDV 125
            P+S +R W  Q+ILV  PS L +    Y  +    H E  G+      L  G++     
Sbjct: 69  FPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNPGKKRG--- 125

Query: 126 PGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCNLSR 184
                  L W YV  L  +  ++ A L + +  Y  + +P    C  +PC   + C +S+
Sbjct: 126 ------GLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISK 179

Query: 185 PSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
           PSEK IF   M   +  C+L   +EL+ L
Sbjct: 180 PSEKNIFTLFMVATAAICILLNLVELIYL 208


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,496,623
Number of Sequences: 37866
Number of extensions: 521718
Number of successful extensions: 1505
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1434
Number of HSP's gapped (non-prelim): 45
length of query: 279
length of database: 18,247,518
effective HSP length: 101
effective length of query: 178
effective length of database: 14,423,052
effective search space: 2567303256
effective search space used: 2567303256
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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