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Search of human proteins with 31543559
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31543559 radial spoke 3 homolog [Homo sapiens]
(560 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31543559 radial spoke 3 homolog [Homo sapiens] 1132 0.0
gi|148746195 trichohyalin [Homo sapiens] 54 5e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 1e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 45 2e-04
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 45 2e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 44 4e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 44 4e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 44 4e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 44 4e-04
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 43 7e-04
gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens] 43 9e-04
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens] 43 9e-04
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens] 43 9e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 42 0.001
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 42 0.001
gi|56549694 enabled homolog isoform a [Homo sapiens] 42 0.001
gi|39930375 enabled homolog isoform b [Homo sapiens] 42 0.001
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 42 0.001
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 42 0.001
gi|92859701 myosin VI [Homo sapiens] 42 0.001
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 42 0.001
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 42 0.001
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 42 0.001
gi|93102424 hypothetical protein LOC23116 [Homo sapiens] 42 0.001
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 42 0.001
gi|219803769 trichoplein [Homo sapiens] 42 0.002
gi|14150056 trichoplein [Homo sapiens] 42 0.002
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 41 0.003
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 41 0.003
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 41 0.003
>gi|31543559 radial spoke 3 homolog [Homo sapiens]
Length = 560
Score = 1132 bits (2927), Expect = 0.0
Identities = 560/560 (100%), Positives = 560/560 (100%)
Query: 1 MTVKPAKAASLARNLAKRRRTYLGGAAGRSQEPEVPCAAVLPGKPGDRNCPEFPPPDRTL 60
MTVKPAKAASLARNLAKRRRTYLGGAAGRSQEPEVPCAAVLPGKPGDRNCPEFPPPDRTL
Sbjct: 1 MTVKPAKAASLARNLAKRRRTYLGGAAGRSQEPEVPCAAVLPGKPGDRNCPEFPPPDRTL 60
Query: 61 GCWATDAAPAAGLCGAGSEPSIAPTSCAGNLPSRPPPLLSPLLASRNPCPWHYLHLSGSH 120
GCWATDAAPAAGLCGAGSEPSIAPTSCAGNLPSRPPPLLSPLLASRNPCPWHYLHLSGSH
Sbjct: 61 GCWATDAAPAAGLCGAGSEPSIAPTSCAGNLPSRPPPLLSPLLASRNPCPWHYLHLSGSH 120
Query: 121 NTLAPTCFKAKLHRKRGSQPPDMASALTDRTSRAPSTYTYTSRPRALPCQRSRYRDSLTQ 180
NTLAPTCFKAKLHRKRGSQPPDMASALTDRTSRAPSTYTYTSRPRALPCQRSRYRDSLTQ
Sbjct: 121 NTLAPTCFKAKLHRKRGSQPPDMASALTDRTSRAPSTYTYTSRPRALPCQRSRYRDSLTQ 180
Query: 181 PDEEPMHYGNIMYDRRVIRGNTYALQTGPLLGRPDSLELQRQREARKRALARKQAQEQLR 240
PDEEPMHYGNIMYDRRVIRGNTYALQTGPLLGRPDSLELQRQREARKRALARKQAQEQLR
Sbjct: 181 PDEEPMHYGNIMYDRRVIRGNTYALQTGPLLGRPDSLELQRQREARKRALARKQAQEQLR 240
Query: 241 PQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMECQTDAFLDRPPTPLFIPAKTGKDVAT 300
PQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMECQTDAFLDRPPTPLFIPAKTGKDVAT
Sbjct: 241 PQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMECQTDAFLDRPPTPLFIPAKTGKDVAT 300
Query: 301 QILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNSERAEV 360
QILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNSERAEV
Sbjct: 301 QILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNSERAEV 360
Query: 361 QRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAARAFAQRYLADLLPSVFGSLRDSG 420
QRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAARAFAQRYLADLLPSVFGSLRDSG
Sbjct: 361 QRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAARAFAQRYLADLLPSVFGSLRDSG 420
Query: 421 YFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGRTVLDMLIREVVEKRLCMYEHGEDTHQS 480
YFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGRTVLDMLIREVVEKRLCMYEHGEDTHQS
Sbjct: 421 YFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGRTVLDMLIREVVEKRLCMYEHGEDTHQS 480
Query: 481 PEPEDEPGGPGAMTESLEASEFLEQSMSQTRELLLDGGYLQRTTYDRRSSQERKFMEERE 540
PEPEDEPGGPGAMTESLEASEFLEQSMSQTRELLLDGGYLQRTTYDRRSSQERKFMEERE
Sbjct: 481 PEPEDEPGGPGAMTESLEASEFLEQSMSQTRELLLDGGYLQRTTYDRRSSQERKFMEERE 540
Query: 541 LLGQDEETAMRKSLGEEELS 560
LLGQDEETAMRKSLGEEELS
Sbjct: 541 LLGQDEETAMRKSLGEEELS 560
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 53.5 bits (127), Expect = 5e-07
Identities = 80/346 (23%), Positives = 141/346 (40%), Gaps = 21/346 (6%)
Query: 219 LQRQREARKRALARKQAQEQLRPQTPEPVEGRKH----------VDVQTELYLEEIADRI 268
L+ QRE + RA R+Q +++ P+ E + R+ ++ + +L E A ++
Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQL 849
Query: 269 IEVDMECQTDAFLDRPPTPLFIPAKTGKDVATQILEG-ELFDFDLEVKPVLEVLVGKTIE 327
E + Q D R + + Q+ E + L KP L+ + K E
Sbjct: 850 QEEEDGLQEDQERRRSQEQ-----RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK--E 902
Query: 328 QSLLEVMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHK 387
Q LL+ EEEEL +R +E R E Q +E+E+ REE+E+R++Q+ E ++
Sbjct: 903 QQLLQE-EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961
Query: 388 HNETSQKIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTME 447
++ Q+ + + R+ E+ + E E+
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Query: 448 YSMVGRTVLDMLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQSM 507
+ + L+RE EKR + + ++E G E+ E LE+
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE-LERQY 1080
Query: 508 SQTRELLLDGGYLQRTTYDRRSSQER-KFMEERELLGQDEETAMRK 552
+ EL + L R ++R QER + E E L Q+EE +R+
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
Score = 44.3 bits (103), Expect = 3e-04
Identities = 57/258 (22%), Positives = 106/258 (41%), Gaps = 36/258 (13%)
Query: 327 EQSLLEVMEEEELANLRASQREYEELRNSERA------EVQRLEEQERRHREEKERRKKQ 380
EQ L E E+ L RE EE++ E E +R +E ER++REE+E ++++
Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
Query: 381 QWEIMHKHNETSQKIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMN 440
+ +++ + E ++ R + + + R Y + D++ + P N
Sbjct: 1181 E-QLLREEQEKRRQERERQYREE------EELQRQKRKQRYRDEDQRSDLKWQWEPEKEN 1233
Query: 441 EVEKTMEY-----SMVGRTVLDMLIREVVEKRLCMYEHGEDTHQSPEPEDE--------- 486
V Y + R + D +R+ ++ + GE + E E
Sbjct: 1234 AVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHF 1293
Query: 487 PGGPGAMTESLEASEFLEQSMSQTRELLLDGGYLQRTTYDRRSSQERKFMEERELLGQDE 546
P E + ++ ++ + ++LL + +R RR +RKF EE +LL + E
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLRE----EREEKRRRQETDRKFREEEQLLQERE 1349
Query: 547 ETAMR-----KSLGEEEL 559
E +R + EEEL
Sbjct: 1350 EQPLRRQERDRKFREEEL 1367
Score = 43.9 bits (102), Expect = 4e-04
Identities = 58/246 (23%), Positives = 104/246 (42%), Gaps = 28/246 (11%)
Query: 334 MEEEELANLRASQREY----EELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHN 389
+EEE+ + + QR++ ++LR ER + QR ++++R+ REE++ R++++ + + +
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQ-QRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Query: 390 ET------SQKIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVE 443
QK+ + ++++ D R G ERD + L+ E E
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQL----RRQEGQQQLRQERDRKFREDEQLLQERE 1632
Query: 444 KTMEYSMV-GRTVLD---MLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEA 499
+ + R L+ L R+ E++L H D E + G E
Sbjct: 1633 EQQLHRQERDRKFLEEEPQLRRQEREQQL---RHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Query: 500 SEFLEQSMSQTRELLLDGGYLQRTTYDRRSSQERKFMEERELLGQDEETAM------RKS 553
+ Q R + +LQ RR ERKF EE +L + E+ + RK
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749
Query: 554 LGEEEL 559
L EE+L
Sbjct: 1750 LEEEQL 1755
Score = 42.4 bits (98), Expect = 0.001
Identities = 47/197 (23%), Positives = 91/197 (46%), Gaps = 23/197 (11%)
Query: 218 ELQRQREARKRALARKQAQEQ----LRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDM 273
E + Q+E R++ L R+Q + + R + E ++ R + Q EE +++++ +
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 274 ECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEV 333
E + + +R L + +D Q+L+ E +K E + + +++ +E
Sbjct: 555 EKRLEQ--ERREQRLKREQEERRD---QLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Query: 334 MEEEELANLRASQREYEELRNSE----------RAEVQRLEEQERRH----REEKERRKK 379
+E+EE R + E EE R + R + R E+QERR REE+E R +
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669
Query: 380 QQWEIMHKHNETSQKIA 396
Q+ + H+ Q++A
Sbjct: 670 QRLKREHEEERREQELA 686
Score = 41.6 bits (96), Expect = 0.002
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 4/75 (5%)
Query: 324 KTIEQSLLEVMEEEELANLRASQREYEELRNSERAEVQR----LEEQERRHREEKERRKK 379
+T+ + E ++EEE R Q E E+LR ER E++R E+Q++R R E++ R+K
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 380 QQWEIMHKHNETSQK 394
Q+ E + E ++
Sbjct: 310 QEEERREQQEERREQ 324
Score = 41.2 bits (95), Expect = 0.003
Identities = 50/236 (21%), Positives = 93/236 (39%), Gaps = 20/236 (8%)
Query: 335 EEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQK 394
EEE+L +R +E R E + +E+E+ REE+E+R++Q+ E ++ E Q+
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
Query: 395 IAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGRT 454
+ + + R+ E +++ L E EK +
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYRE--------EEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 455 VLDMLIREVVEKRLCMYEHGEDTHQSPEPEDE----------PGGPGAMTESLEASEFLE 504
+ L R+ ++R + D EPE E G LE S+ +
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260
Query: 505 QSMSQTRELLLDGGYLQRTTYDRR--SSQERKFMEERELLGQDEETAMRKSLGEEE 558
+ Q + LL + +RR ++R F EE +L ++++ A R+ +E
Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQE 1316
Score = 38.9 bits (89), Expect = 0.013
Identities = 51/220 (23%), Positives = 97/220 (44%), Gaps = 18/220 (8%)
Query: 346 QREYEELRNSERAEVQRLEEQERRHREEKERRKKQ----QWEIMHKHNETSQKIAARAFA 401
++E EE R +E+Q +E+ER HR+++E +++ QW+ K Q+++AR
Sbjct: 732 RQEQEEKRRRRESELQ-WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL 790
Query: 402 QRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGRTVLDMLIR 461
+ L + R+ + + E++ E++ E + R ++
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Query: 462 EVV------EKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQSMSQTRELLL 515
E ++R E D + E+E +L A L++ + + ++LL
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEE---RKRRRHTLYAKPALQEQLRKEQQLLQ 907
Query: 516 -DGGYLQRTTYD--RRSSQERKFMEERELLGQDEETAMRK 552
+ LQR + RR QER++ EE E L Q+EE +R+
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREE-EQLQQEEEQLLRE 946
Score = 38.5 bits (88), Expect = 0.016
Identities = 63/244 (25%), Positives = 105/244 (43%), Gaps = 16/244 (6%)
Query: 170 QRSRYRDSLTQPDEEPMHYGNIMYDRRVIRGNTYALQTGPLLGRPDSLELQRQREARKRA 229
Q+ R L + EE H +RR R + L R + E + ++E RK+
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE-RHEQERRKQQ 475
Query: 230 LARKQAQEQ----LRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMECQTDAFLDRPP 285
L R Q +E+ L+ + E E ++ + Q EE ++ ++ E + R
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 286 TPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQ--SLLEVMEEEELANLR 343
L + ++ Q+L+ E + LE + + L + E+ LL+ EE L+
Sbjct: 536 QQL---RREQEERREQLLKREE-EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 344 ASQREYEELRNSERAEVQRLEEQERRH----REEKERRKKQQWEIMHKHNETSQKIAARA 399
Q E E R +R EV+RLE++ERR REE E ++QQ + E Q+ R
Sbjct: 592 REQEERLEQR-LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE 650
Query: 400 FAQR 403
+R
Sbjct: 651 QQER 654
Score = 37.4 bits (85), Expect = 0.037
Identities = 83/390 (21%), Positives = 149/390 (38%), Gaps = 69/390 (17%)
Query: 182 DEEPMHYGNIMYDRRVIRGNTYALQTGPLLGRPDSLELQRQREARKRALARKQAQEQLRP 241
+EEP + + +R L+ L E Q+QR R++ L RKQ +E+ R
Sbjct: 262 EEEPQRQRELQEEEEQLR----KLERQELRRERQEEEQQQQRLRREQQLRRKQEEER-RE 316
Query: 242 QTPEPVEGRKHVDVQTELYLEEIADRIIEVDMECQTDAFLDRPPTPLFIPAKTGKDVATQ 301
Q E E ++ + Q EE ++ + + E + + L R + ++ +
Sbjct: 317 QQEERREQQERREQQ-----EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 302 ILEGELF-------DFDLEVKPVLEVLVGKTIEQSLL---EVMEEEELANLRASQREYEE 351
E +L + L + L EQ L ++ E++L + +RE EE
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 352 LRNSERAEVQRLEEQERRHREEKERRKKQQWEI-MHKHNETSQKIAARAFAQRYLADLLP 410
R+ ++ E +R E++ +R +EE+ K++ E H+ Q++ +R
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR------ 485
Query: 411 SVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGRTVLDMLIREVVEKRLCM 470
ER WL E E+ E L E E+RL
Sbjct: 486 ----------------ER--------WLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 471 YEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQSMSQTRELLLDGGYLQRTTYDRRSS 530
E E + + L + + L + + RE LL +R +RR
Sbjct: 522 QEEEE----------------RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
Query: 531 QERKFMEER--ELLGQDEETAMRKSLGEEE 558
+ ++ EER +LL ++EE ++ E+E
Sbjct: 566 RLKREQEERRDQLLKREEERRQQRLKREQE 595
Score = 36.2 bits (82), Expect = 0.082
Identities = 51/221 (23%), Positives = 89/221 (40%), Gaps = 29/221 (13%)
Query: 337 EELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQW---EIMHKHNETSQ 393
EE LR +RE + L+ ++ Q E+Q R+ R+ K R ++QQ E K E Q
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 394 KIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGR 453
++ + +++L + LR + E + L E+ + R
Sbjct: 1438 QVRRQERERKFLEE-----EQQLRQERHRKFREEEQL-------LQEREEQQLHRQERDR 1485
Query: 454 TVLDMLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQSMSQTREL 513
L+ + ++R + E Q PE + LE + L + Q R+
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPE-----------RKFLEEEQQLHRQQRQ-RKF 1533
Query: 514 LLDGGYLQRTT--YDRRSSQERKFMEERELLGQDEETAMRK 552
L + L+R RR ++RKF EE +L + EE + +
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
Score = 36.2 bits (82), Expect = 0.082
Identities = 32/161 (19%), Positives = 77/161 (47%), Gaps = 6/161 (3%)
Query: 219 LQRQREARKRALARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMECQTD 278
L+ +++ R++ RK +++LR Q PE RK ++ + +L+ ++ + ++ + + +
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPE----RKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543
Query: 279 AFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEE 338
+ + + + + E +L + + K LE + EQ + +E++
Sbjct: 1544 ERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603
Query: 339 LANLRASQREYEELRNSERAEVQRLEEQERR--HREEKERR 377
L Q+ +E R + Q L+E+E + HR+E++R+
Sbjct: 1604 LRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Score = 35.8 bits (81), Expect = 0.11
Identities = 55/223 (24%), Positives = 85/223 (38%), Gaps = 25/223 (11%)
Query: 336 EEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQKI 395
EEE + +RE + R E QRL+ QE R ++ R +QQ + + E +++
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ--LRREQEERREQL 549
Query: 396 AARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGRTV 455
R +R + R+ D + + E L E E+ +E
Sbjct: 550 LKREEEKRLEQERREQRL--KREQEERRDQLLKREEERRQQRLKREQEERLE-------- 599
Query: 456 LDMLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQSMSQTRELLL 515
L RE VE RL E E + EPE+E + L++ E E+ Q R
Sbjct: 600 -QRLKREEVE-RLEQEERREQRLKREEPEEE-----RRQQLLKSEEQEERRQQQLRR--- 649
Query: 516 DGGYLQRTTYDRRSSQERKFMEERELLGQDEETAMRKSLGEEE 558
Q R +E + E+ L + EE + L EEE
Sbjct: 650 ---EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Score = 35.8 bits (81), Expect = 0.11
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 335 EEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQK 394
EEEE R + EE R E AE EEQE+ K R K QW++ + + K
Sbjct: 663 EEEERLEQRLKREHEEERREQELAE----EEQEQARERIKSRIPKWQWQLESEADARQSK 718
Query: 395 IAAR 398
+ +R
Sbjct: 719 VYSR 722
Score = 35.4 bits (80), Expect = 0.14
Identities = 19/49 (38%), Positives = 31/49 (63%), Gaps = 4/49 (8%)
Query: 332 EVMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQ 380
+++EEE+L +RE ++LR ER R EEQ R+ REE++ R ++
Sbjct: 1748 KILEEEQLR----PEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQE 1792
Score = 34.3 bits (77), Expect = 0.31
Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 7/67 (10%)
Query: 335 EEEELANLRASQREYEELRNSERAEVQ-------RLEEQERRHREEKERRKKQQWEIMHK 387
EEE+L QR +E RAE Q R EEQE EE++RR++++ ++ +
Sbjct: 1824 EEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883
Query: 388 HNETSQK 394
H QK
Sbjct: 1884 HIRRQQK 1890
Score = 33.9 bits (76), Expect = 0.41
Identities = 19/46 (41%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
Query: 336 EEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQ 381
EE+ A S+RE +EL E E +R +E+ER+ REE RR++++
Sbjct: 1848 EEQFATQEKSRREEQELWQEE--EQKRRQERERKLREEHIRRQQKE 1891
Score = 33.5 bits (75), Expect = 0.53
Identities = 17/52 (32%), Positives = 32/52 (61%), Gaps = 4/52 (7%)
Query: 336 EEELANLRASQREYEELRNSERAEV----QRLEEQERRHREEKERRKKQQWE 383
EEE R +R+ +E +E E +RLE+++R+ R+E+ R++Q+W+
Sbjct: 130 EEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQ 181
Score = 33.5 bits (75), Expect = 0.53
Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Query: 327 EQSLLEVMEEEELANLRASQR-EYEELRNSERAEVQRLEEQERRHREEKER---RKKQQW 382
E+ LL+ EE+ L ++ EELR+ E+ + LEE++R R+E+ER +++QQ
Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGR-KFLEEEQRLRRQERERKFLKEEQQL 1399
Query: 383 EIMHKHNETSQ 393
+ + Q
Sbjct: 1400 RCQEREQQLRQ 1410
Score = 32.7 bits (73), Expect = 0.90
Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 4/47 (8%)
Query: 335 EEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQ 381
EEE+L +RE ++LR+ E R EEQ R+ REE++ R +Q+
Sbjct: 1775 EEEQLRQ----EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Score = 32.3 bits (72), Expect = 1.2
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 22/90 (24%)
Query: 327 EQSLLEVMEEEELANLRASQ--REYEELRNSERAEVQ-----------------RLEEQE 367
E+ L + EE++L + + + RE E+LR ER E Q +LEEQE
Sbjct: 1776 EEQLRQEREEQQLRSQESDRKFREEEQLR-QEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 368 RRHREEKER--RKKQQWEIMHKHNETSQKI 395
+R R+E++R R ++Q+ K Q++
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKSRREEQEL 1864
Score = 32.0 bits (71), Expect = 1.5
Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 498 EASEFLEQSMSQTRELL-LDGGYLQRTTYDRRSSQERKFMEERELLGQDEETAMRK---S 553
E EF ++ + RELL L + RR Q+R F EE E + ET +RK
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Query: 554 LGEEE 558
L EEE
Sbjct: 260 LQEEE 264
Score = 32.0 bits (71), Expect = 1.5
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 7/65 (10%)
Query: 332 EVMEEEELANLRASQREYEELRNSERAEVQ--RLEEQERRHREEKERRKKQQWEIMHKHN 389
E +EE+L +RE ELR R E Q R E Q+R +EE+E+ +++ ++ K
Sbjct: 203 EFPDEEQLR-----RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEE 257
Query: 390 ETSQK 394
E Q+
Sbjct: 258 EKLQE 262
Score = 32.0 bits (71), Expect = 1.5
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 5/73 (6%)
Query: 328 QSLLEVMEEEELAN--LRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIM 385
Q LL+ E+EE LR Q+E E R E +RLE++ +R EE +++Q
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEE---ERREQELAE 687
Query: 386 HKHNETSQKIAAR 398
+ + ++I +R
Sbjct: 688 EEQEQARERIKSR 700
Score = 32.0 bits (71), Expect = 1.5
Identities = 49/230 (21%), Positives = 89/230 (38%), Gaps = 30/230 (13%)
Query: 334 MEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQ 393
+ E+ LRA +R+ E R L E+E + + ++RR++++ E+ E
Sbjct: 790 LREQRERQLRAEERQQREQRF--------LPEEEEKEQRRRQRREREK-ELQFLEEEEQL 840
Query: 394 KIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGR 453
+ RA + D L R D R W + E K +++ +
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR--------WQLEEERKRRRHTLYAK 892
Query: 454 TVLDMLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQSMSQTREL 513
L +R+ E++L E E + E E + + EQ + + RE
Sbjct: 893 PALQEQLRK--EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE- 949
Query: 514 LLDGGYLQRTTYDRRSSQERKFME-ERELLGQDEETAMR----KSLGEEE 558
+R +R+ +++K + E +LLG++ E R K EEE
Sbjct: 950 -----KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994
Score = 32.0 bits (71), Expect = 1.5
Identities = 55/235 (23%), Positives = 98/235 (41%), Gaps = 30/235 (12%)
Query: 335 EEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQ----WEIMHKHNE 390
EEE+L +RE ++L ER + + LEE+++ R+E++R+ ++Q E K E
Sbjct: 1465 EEEQLLQ----EREEQQLHRQER-DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 391 TSQKIAARAFAQRYLAD---LLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTME 447
Q++ + +++L + L G R +RD + L E E+ +
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ-------DRDRKFREEEQLRQEREE-QQ 1571
Query: 448 YSMVGRTVLDMLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQS- 506
S R L + V ++ + ED Q E + E L Q
Sbjct: 1572 LSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
Query: 507 -------MSQTRELLLDGGYLQRTTYDR--RSSQERKFMEERELLGQDEETAMRK 552
+ R+ L + L+R ++ R ++RKF EE +LL + EE +R+
Sbjct: 1632 EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRR 1686
Score = 30.4 bits (67), Expect = 4.5
Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 11/77 (14%)
Query: 327 EQSLLEVMEEEELANLRASQR---------EYEELRNSERAEVQRLEEQERRHREEKERR 377
EQ L E EE+E A R R + R S+ R +E +RR +E++E+R
Sbjct: 682 EQELAE--EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR 739
Query: 378 KKQQWEIMHKHNETSQK 394
++++ E+ + E + +
Sbjct: 740 RRRESELQWQEEERAHR 756
Score = 30.0 bits (66), Expect = 5.9
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 327 EQSLLEVMEEEELANLRASQ--REYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEI 384
E+ LL EE+ + RE E+L + R +E++R+ REE+ R ++Q +
Sbjct: 1317 EKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKF 1376
Query: 385 MHKHNETSQKIAARAF 400
+ + ++ R F
Sbjct: 1377 LEEEQRLRRQERERKF 1392
Score = 29.6 bits (65), Expect = 7.7
Identities = 17/68 (25%), Positives = 33/68 (48%)
Query: 327 EQSLLEVMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMH 386
E+ L + E+E+L ++ EE + E Q+L QER + +E + +Q+ E
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 387 KHNETSQK 394
++ S +
Sbjct: 1788 LRSQESDR 1795
Score = 29.3 bits (64), Expect = 10.0
Identities = 13/46 (28%), Positives = 25/46 (54%)
Query: 335 EEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQ 380
EE+EL +R E R ++R +++E+RHR+ E + ++
Sbjct: 1860 EEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/231 (21%), Positives = 102/231 (44%), Gaps = 20/231 (8%)
Query: 335 EEEELANLRASQREYEELRNSE---RAEVQRLEEQERRHREEKE---RRKKQQWEIMHKH 388
+E+EL RE +ELR E + + +++ EQE + RE++E R++++ WE +
Sbjct: 326 QEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 385
Query: 389 NETSQKIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTMEY 448
E QK+ + + L +R+ ++ +E+ M E +K E
Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK----------MREEKKMQEQ 435
Query: 449 SMVGRTVLD-MLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQSM 507
R + M E + +R E+T + E + + + E E+ +Q +
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ--EEKEWQQQRL 493
Query: 508 SQTRELLLDGGYLQRTTYDRRSSQERKFMEERELLGQDEETAMRKSLGEEE 558
+ +E L + +Q ++ QE K ++ E+ GQ+++ ++ + E+E
Sbjct: 494 PEQKEKLWEQEKMQEQE-EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Score = 34.3 bits (77), Expect = 0.31
Identities = 42/217 (19%), Positives = 91/217 (41%), Gaps = 21/217 (9%)
Query: 332 EVMEEEELANLRASQREYEELRNSERA-EVQRLEEQERRHREEKERRKKQQWEIMHKHNE 390
++ ++EE + ++E + E+ E +R+ E+E++ REE+E ++Q+ E M + E
Sbjct: 559 KMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKMQEQEE 617
Query: 391 TSQKIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTMEYSM 450
Q+ + + Q + ++ E+ E LP + EK E+
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEK--MWEQEEKMWEQQRLP---EQKEKLWEHEK 672
Query: 451 VGRTVLDMLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQSMSQT 510
+ ++ E+ ++E + ++ E E + M E E+SM +
Sbjct: 673 MQEQ------EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE--------EESMRER 718
Query: 511 RELLLDGGYLQRTTYDRRSSQERKFMEERELLGQDEE 547
+ + + + R ++ QE K E+ E + + EE
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755
Score = 34.3 bits (77), Expect = 0.31
Identities = 34/170 (20%), Positives = 74/170 (43%), Gaps = 9/170 (5%)
Query: 220 QRQREARKRALARKQAQEQLRPQTPEPVEGRKHVDVQTELYLE------EIADRIIEVDM 273
+R+++ R+ ++ +E+++ Q + E + + Q E E E +++ E +
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652
Query: 274 ECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEV 333
+ L L+ K + Q E ++++ + K E KT +Q ++
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ-EKKTWDQE--KM 709
Query: 334 MEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWE 383
EEE + RE EE+ + ++Q EE+ + EE ++++ WE
Sbjct: 710 REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE 759
Score = 33.1 bits (74), Expect = 0.69
Identities = 37/187 (19%), Positives = 83/187 (44%), Gaps = 15/187 (8%)
Query: 218 ELQRQREARKRALARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMECQT 277
+++ + R+R ++ +E +R Q + E + + Q E E+ E M+ Q
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ------EEKMQEQE 637
Query: 278 DAFLDRPPTPLFIPAKTGKDVATQILEGELFDFD-LEVKPVLEVLVGKTIEQSLLE--VM 334
+ ++ K + + +L++ + ++ + ++ K EQ +E
Sbjct: 638 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQ 697
Query: 335 EEEELANLRASQREYEELRNSE---RAEVQRLEEQERRHREEKER---RKKQQWEIMHKH 388
E+E+ + RE E +R E R E + + EQE + +E++E+ ++++ WE K
Sbjct: 698 EQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKM 757
Query: 389 NETSQKI 395
E +K+
Sbjct: 758 WEQEEKM 764
Score = 32.3 bits (72), Expect = 1.2
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 334 MEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEK-ERRKKQQWE 383
M+E+E ++ EE R ER + R EE+ R +EEK +++++ WE
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Score = 32.0 bits (71), Expect = 1.5
Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
Query: 327 EQSLLEVMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEK--------ERRK 378
E+ + + +E+E ++ EE R ER + R EE+ R +EEK + ++
Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 623
Query: 379 KQQWEIMHKHNETSQKI 395
++ WE K E +K+
Sbjct: 624 EKMWEQEEKMQEQEEKM 640
Score = 29.6 bits (65), Expect = 7.7
Identities = 22/99 (22%), Positives = 46/99 (46%), Gaps = 7/99 (7%)
Query: 302 ILEGELFDFDLEVKPV------LEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNS 355
+ E E + L VK + + L+ + +L E M +E LR +++ +
Sbjct: 236 LAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE-EELREQEKKIRKQEEK 294
Query: 356 ERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQK 394
+ +RL EQE + RE++E+ +Q+ + + E ++
Sbjct: 295 MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQ 333
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 45.1 bits (105), Expect = 2e-04
Identities = 64/261 (24%), Positives = 120/261 (45%), Gaps = 23/261 (8%)
Query: 304 EGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQR--EYEELRNSERAEVQ 361
+GE + + E K K ++++L ++ EEEE +R EEL ++R E +
Sbjct: 322 KGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELE-AKRKEEE 380
Query: 362 RLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAARAFAQRYLADL-LPSVFGSLRDSG 420
RLE+++R +++KE+ +K++ + K SQ+ ARA A+ L L V +DS
Sbjct: 381 RLEQEKRERKKQKEKERKERLKKEGKLLTKSQR-EARARAEATLKLLQAQGVEVPSKDSL 439
Query: 421 YFYDPIERDIEIGFLPWLM--NEVEKTMEYSMVGRTVLDMLIREVVEKRLCMYEHGEDTH 478
PI D + +P + EV ++ME ++++ + V EK E+T
Sbjct: 440 PKKRPIYEDKKRKKIPQQLESKEVSESMELC----AAVEVMEQGVPEK--------EETP 487
Query: 479 QSPEPEDEPGGPGAMTESLEASEFLEQSMS-QTRELLLDGGYLQRTTYDRRSSQERKFME 537
EPE+E A + EA E++ + ++ ++ ++ + +E + +
Sbjct: 488 PPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE---VKENPEEEEEEEEEEEED 544
Query: 538 ERELLGQDEETAMRKSLGEEE 558
E ++EE S G+EE
Sbjct: 545 EESEEEEEEEGESEGSEGDEE 565
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 44.7 bits (104), Expect = 2e-04
Identities = 53/190 (27%), Positives = 80/190 (42%), Gaps = 24/190 (12%)
Query: 215 DSLELQRQREARKRALARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIA---DRIIEV 271
D E+ + E ++ A + +E R E E + D + E EE D E
Sbjct: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEE-DAEAEAETEETRAEEDEEEEE 61
Query: 272 DMECQTDAFLDRPPTPL-FIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSL 330
E + + P P F+P V +I +GE DFD + +E + + Q+L
Sbjct: 62 AKEAEDGPMEESKPKPRSFMPNL----VPPKIPDGERVDFDDIHRKRMEKDLNEL--QAL 115
Query: 331 LEV------MEEEELANL-------RASQREYEELRNSERAEVQRLEEQERRHREEKERR 377
+E EEEEL +L RA + E + +RN E Q +ER REE+E R
Sbjct: 116 IEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENR 175
Query: 378 KKQQWEIMHK 387
+K + E K
Sbjct: 176 RKAEDEARKK 185
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/103 (32%), Positives = 57/103 (55%), Gaps = 13/103 (12%)
Query: 305 GELFDFDLEVK---PVLEVLVGKTIEQSLLEVMEEEEL-ANLRASQRE-----YEELRNS 355
G ++D L+ P LE L + +E++ +E+E A +RA + E EELR
Sbjct: 701 GSVWDLPLDTTTPGPALEQL--QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQ 758
Query: 356 ERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAAR 398
+ ++R +E+ER+ REE+E +++Q E + + E Q+IA R
Sbjct: 759 QEEILRRQQEEERKRREEEELARRKQEEALRRQRE--QEIALR 799
Score = 38.1 bits (87), Expect = 0.022
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 30/198 (15%)
Query: 218 ELQRQREARKRA--LARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMEC 275
E +RQ E R++ + R+Q +E+ + + E + RK + +EIA R + E
Sbjct: 748 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 807
Query: 276 QTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVME 335
Q ++ A + LE + + K E L+ K E++ E
Sbjct: 808 QQ------------------QEEALRRLEERRREEEERRKQ--EELLRKQEEEAAKWARE 847
Query: 336 EEELANLRASQREYEE--LRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQ 393
EEE +QR EE LR E A R EE+ER+ +E + +R+K+ + E +
Sbjct: 848 EEE------AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 901
Query: 394 KIAARAFAQRYLADLLPS 411
++ + Q+ LPS
Sbjct: 902 RLQQQQQQQQLAQMKLPS 919
Score = 32.3 bits (72), Expect = 1.2
Identities = 45/214 (21%), Positives = 95/214 (44%), Gaps = 39/214 (18%)
Query: 220 QRQREARKRA----LARKQAQEQLRPQTPEPVEGRKHVDV----QTELYLEEIADRIIEV 271
++Q E RKR LAR++ +E LR Q + + R+ + Q E L + +R E
Sbjct: 765 RQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE 824
Query: 272 DMECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELF----------------DFDLEVK 315
+ + + L + A+ ++ ++ E L +LEV+
Sbjct: 825 EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
Query: 316 PVLEVLVGKTIEQSLL----EVMEEEELANLRA-SQREYEELRNSER---------AEVQ 361
E++ + +Q L + ++++LA ++ S + + N+ AE+Q
Sbjct: 885 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 944
Query: 362 RLEEQ-ERRHREEKERRKKQQWEIMHKHNETSQK 394
+LEE+ ER+ REE+ R++++ + + + + Q+
Sbjct: 945 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 978
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/103 (32%), Positives = 57/103 (55%), Gaps = 13/103 (12%)
Query: 305 GELFDFDLEVK---PVLEVLVGKTIEQSLLEVMEEEEL-ANLRASQRE-----YEELRNS 355
G ++D L+ P LE L + +E++ +E+E A +RA + E EELR
Sbjct: 728 GSVWDLPLDTTTPGPALEQL--QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQ 785
Query: 356 ERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAAR 398
+ ++R +E+ER+ REE+E +++Q E + + E Q+IA R
Sbjct: 786 QEEILRRQQEEERKRREEEELARRKQEEALRRQRE--QEIALR 826
Score = 38.1 bits (87), Expect = 0.022
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 30/198 (15%)
Query: 218 ELQRQREARKRA--LARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMEC 275
E +RQ E R++ + R+Q +E+ + + E + RK + +EIA R + E
Sbjct: 775 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 834
Query: 276 QTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVME 335
Q ++ A + LE + + K E L+ K E++ E
Sbjct: 835 QQ------------------QEEALRRLEERRREEEERRKQ--EELLRKQEEEAAKWARE 874
Query: 336 EEELANLRASQREYEE--LRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQ 393
EEE +QR EE LR E A R EE+ER+ +E + +R+K+ + E +
Sbjct: 875 EEE------AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 928
Query: 394 KIAARAFAQRYLADLLPS 411
++ + Q+ LPS
Sbjct: 929 RLQQQQQQQQLAQMKLPS 946
Score = 32.3 bits (72), Expect = 1.2
Identities = 45/214 (21%), Positives = 95/214 (44%), Gaps = 39/214 (18%)
Query: 220 QRQREARKRA----LARKQAQEQLRPQTPEPVEGRKHVDV----QTELYLEEIADRIIEV 271
++Q E RKR LAR++ +E LR Q + + R+ + Q E L + +R E
Sbjct: 792 RQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE 851
Query: 272 DMECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELF----------------DFDLEVK 315
+ + + L + A+ ++ ++ E L +LEV+
Sbjct: 852 EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 911
Query: 316 PVLEVLVGKTIEQSLL----EVMEEEELANLRA-SQREYEELRNSER---------AEVQ 361
E++ + +Q L + ++++LA ++ S + + N+ AE+Q
Sbjct: 912 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 971
Query: 362 RLEEQ-ERRHREEKERRKKQQWEIMHKHNETSQK 394
+LEE+ ER+ REE+ R++++ + + + + Q+
Sbjct: 972 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 1005
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/103 (32%), Positives = 57/103 (55%), Gaps = 13/103 (12%)
Query: 305 GELFDFDLEVK---PVLEVLVGKTIEQSLLEVMEEEEL-ANLRASQRE-----YEELRNS 355
G ++D L+ P LE L + +E++ +E+E A +RA + E EELR
Sbjct: 707 GSVWDLPLDTTTPGPALEQL--QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQ 764
Query: 356 ERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAAR 398
+ ++R +E+ER+ REE+E +++Q E + + E Q+IA R
Sbjct: 765 QEEILRRQQEEERKRREEEELARRKQEEALRRQRE--QEIALR 805
Score = 38.1 bits (87), Expect = 0.022
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 30/198 (15%)
Query: 218 ELQRQREARKRA--LARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMEC 275
E +RQ E R++ + R+Q +E+ + + E + RK + +EIA R + E
Sbjct: 754 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 813
Query: 276 QTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVME 335
Q ++ A + LE + + K E L+ K E++ E
Sbjct: 814 QQ------------------QEEALRRLEERRREEEERRKQ--EELLRKQEEEAAKWARE 853
Query: 336 EEELANLRASQREYEE--LRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQ 393
EEE +QR EE LR E A R EE+ER+ +E + +R+K+ + E +
Sbjct: 854 EEE------AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 907
Query: 394 KIAARAFAQRYLADLLPS 411
++ + Q+ LPS
Sbjct: 908 RLQQQQQQQQLAQMKLPS 925
Score = 32.3 bits (72), Expect = 1.2
Identities = 45/214 (21%), Positives = 95/214 (44%), Gaps = 39/214 (18%)
Query: 220 QRQREARKRA----LARKQAQEQLRPQTPEPVEGRKHVDV----QTELYLEEIADRIIEV 271
++Q E RKR LAR++ +E LR Q + + R+ + Q E L + +R E
Sbjct: 771 RQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE 830
Query: 272 DMECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELF----------------DFDLEVK 315
+ + + L + A+ ++ ++ E L +LEV+
Sbjct: 831 EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
Query: 316 PVLEVLVGKTIEQSLL----EVMEEEELANLRA-SQREYEELRNSER---------AEVQ 361
E++ + +Q L + ++++LA ++ S + + N+ AE+Q
Sbjct: 891 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 950
Query: 362 RLEEQ-ERRHREEKERRKKQQWEIMHKHNETSQK 394
+LEE+ ER+ REE+ R++++ + + + + Q+
Sbjct: 951 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/103 (32%), Positives = 57/103 (55%), Gaps = 13/103 (12%)
Query: 305 GELFDFDLEVK---PVLEVLVGKTIEQSLLEVMEEEEL-ANLRASQRE-----YEELRNS 355
G ++D L+ P LE L + +E++ +E+E A +RA + E EELR
Sbjct: 707 GSVWDLPLDTTTPGPALEQL--QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQ 764
Query: 356 ERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAAR 398
+ ++R +E+ER+ REE+E +++Q E + + E Q+IA R
Sbjct: 765 QEEILRRQQEEERKRREEEELARRKQEEALRRQRE--QEIALR 805
Score = 38.1 bits (87), Expect = 0.022
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 30/198 (15%)
Query: 218 ELQRQREARKRA--LARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMEC 275
E +RQ E R++ + R+Q +E+ + + E + RK + +EIA R + E
Sbjct: 754 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 813
Query: 276 QTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVME 335
Q ++ A + LE + + K E L+ K E++ E
Sbjct: 814 QQ------------------QEEALRRLEERRREEEERRKQ--EELLRKQEEEAAKWARE 853
Query: 336 EEELANLRASQREYEE--LRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQ 393
EEE +QR EE LR E A R EE+ER+ +E + +R+K+ + E +
Sbjct: 854 EEE------AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 907
Query: 394 KIAARAFAQRYLADLLPS 411
++ + Q+ LPS
Sbjct: 908 RLQQQQQQQQLAQMKLPS 925
Score = 32.3 bits (72), Expect = 1.2
Identities = 45/214 (21%), Positives = 95/214 (44%), Gaps = 39/214 (18%)
Query: 220 QRQREARKRA----LARKQAQEQLRPQTPEPVEGRKHVDV----QTELYLEEIADRIIEV 271
++Q E RKR LAR++ +E LR Q + + R+ + Q E L + +R E
Sbjct: 771 RQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE 830
Query: 272 DMECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELF----------------DFDLEVK 315
+ + + L + A+ ++ ++ E L +LEV+
Sbjct: 831 EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
Query: 316 PVLEVLVGKTIEQSLL----EVMEEEELANLRA-SQREYEELRNSER---------AEVQ 361
E++ + +Q L + ++++LA ++ S + + N+ AE+Q
Sbjct: 891 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 950
Query: 362 RLEEQ-ERRHREEKERRKKQQWEIMHKHNETSQK 394
+LEE+ ER+ REE+ R++++ + + + + Q+
Sbjct: 951 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 43.1 bits (100), Expect = 7e-04
Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 23/172 (13%)
Query: 233 KQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIA---DRIIEVDMECQTDAFLDRPPTPL- 288
++ E+ + E E D + E EE D E E + + P P
Sbjct: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRS 64
Query: 289 FIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEV------MEEEELANL 342
F+P V +I +GE DFD + +E + + Q+L+E EEEEL +L
Sbjct: 65 FMPNL----VPPKIPDGERVDFDDIHRKRMEKDLNEL--QALIEAHFENRKKEEEELVSL 118
Query: 343 -------RASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHK 387
RA + E + +RN E Q +ER REE+E R+K + E K
Sbjct: 119 KDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKK 170
>gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens]
Length = 251
Score = 42.7 bits (99), Expect = 9e-04
Identities = 45/126 (35%), Positives = 55/126 (43%), Gaps = 37/126 (29%)
Query: 283 RPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVM-------- 334
RP P IP K I EGE DFD + K +E+ LLE+
Sbjct: 33 RPVVPPLIPPK--------IPEGERVDFD--------DIHRKRMEKDLLELQTLIDVHFE 76
Query: 335 ----EEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNE 390
EEEEL L+ E E R SERAE QR R +E+ER+ K E M K E
Sbjct: 77 QRKKEEEELVALK----ERIERRRSERAEQQRF-----RTEKERERQAKLAEEKMRKEEE 127
Query: 391 TSQKIA 396
++K A
Sbjct: 128 EAKKRA 133
>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
Length = 262
Score = 42.7 bits (99), Expect = 9e-04
Identities = 45/126 (35%), Positives = 55/126 (43%), Gaps = 37/126 (29%)
Query: 283 RPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVM-------- 334
RP P IP K I EGE DFD + K +E+ LLE+
Sbjct: 44 RPVVPPLIPPK--------IPEGERVDFD--------DIHRKRMEKDLLELQTLIDVHFE 87
Query: 335 ----EEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNE 390
EEEEL L+ E E R SERAE QR R +E+ER+ K E M K E
Sbjct: 88 QRKKEEEELVALK----ERIERRRSERAEQQRF-----RTEKERERQAKLAEEKMRKEEE 138
Query: 391 TSQKIA 396
++K A
Sbjct: 139 EAKKRA 144
>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
Length = 278
Score = 42.7 bits (99), Expect = 9e-04
Identities = 45/126 (35%), Positives = 55/126 (43%), Gaps = 37/126 (29%)
Query: 283 RPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVM-------- 334
RP P IP K I EGE DFD + K +E+ LLE+
Sbjct: 44 RPVVPPLIPPK--------IPEGERVDFD--------DIHRKRMEKDLLELQTLIDVHFE 87
Query: 335 ----EEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNE 390
EEEEL L+ E E R SERAE QR R +E+ER+ K E M K E
Sbjct: 88 QRKKEEEELVALK----ERIERRRSERAEQQRF-----RTEKERERQAKLAEEKMRKEEE 138
Query: 391 TSQKIA 396
++K A
Sbjct: 139 EAKKRA 144
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 42.4 bits (98), Expect = 0.001
Identities = 69/300 (23%), Positives = 122/300 (40%), Gaps = 39/300 (13%)
Query: 125 PTCFKAKLHRKRGSQPPDMASALTDRTSRAPSTYTYTSRPRALPCQRSRY----RDSLTQ 180
P + K K+ D L D + P + T +S PC S+ R L
Sbjct: 444 PQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSS-----PCPASKVVRPLRTFLHT 498
Query: 181 PDEEPMHYGNIMYDRRVIRGNTYALQTGPLLGRPDSLELQRQREARKRALARKQAQEQLR 240
M R V++ ++ + PL P ++++R+ R L RK+ EQLR
Sbjct: 499 VQRNQMLMTPTSAPRSVMK--SFIKRNTPLRMDPKCSFVEKERQ-RLENLRRKEEAEQLR 555
Query: 241 PQTPEPVEGRKHVDVQTELYLEEIADRIIEV-----DMECQTDAFLDRPPTPLFIPAKTG 295
Q E + R+ +V +L EE ++++ M+ + +++ I KT
Sbjct: 556 RQKVEEDKRRRLEEV--KLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ--IDEKTE 611
Query: 296 KDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNS 355
K ++ E + + K +E+ +EEE LR Q+E EE R+
Sbjct: 612 KAKEERLAE----------EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQ 661
Query: 356 ERAEVQRLEEQER--------RHREEKERRKKQQWEIMHKHNETSQKIAARAFAQRYLAD 407
E + ++ EEQER R E++E+ +++Q + E ++ R +R LA+
Sbjct: 662 ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAE 721
Score = 35.0 bits (79), Expect = 0.18
Identities = 56/226 (24%), Positives = 88/226 (38%), Gaps = 27/226 (11%)
Query: 335 EEEELANLRASQREYEELRNSERAEVQRLE-EQERRHREEKERRKKQQWEIMHKHNETSQ 393
E + L NLR + E E+LR + E +R E+ + REE+ R+ Q E + + E +
Sbjct: 538 ERQRLENLRRKE-EAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKK 596
Query: 394 KIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGR 453
K + FAQ + E + M EVE + R
Sbjct: 597 KQIEQKFAQ----------IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 646
Query: 454 TVLDMLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQSMSQTREL 513
L L +E E+R H E + E E E + ++ EA EQ + RE
Sbjct: 647 R-LRWLQQEEEERR-----HQELLQKKKEEEQE-----RLRKAAEAKRLAEQREQERRE- 694
Query: 514 LLDGGYLQRTTYDRRSSQERKFMEERELLGQDEETAMRKSLGEEEL 559
+ +R +RR + R+ +ER+L Q+ + E EL
Sbjct: 695 -QERREQERREQERREQERRE--QERQLAEQERRREQERLQAEREL 737
Score = 34.3 bits (77), Expect = 0.31
Identities = 53/220 (24%), Positives = 95/220 (43%), Gaps = 36/220 (16%)
Query: 213 RPDSLELQRQREARKRALARKQAQEQLRPQTPEPVEGR-KHVDVQTELYLEEIADRIIEV 271
R + ++L+R+ RK AR++ EQ++ + + +E + +D +TE EE R+ E
Sbjct: 566 RLEEVKLKREERLRKVLQARERV-EQMKEEKKKQIEQKFAQIDEKTEKAKEE---RLAEE 621
Query: 272 DMECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQS-- 329
+ + A + A+ ++ + L + E + E+L K E+
Sbjct: 622 KAKKKAAAKKMEE-----VEARRKQEEEARRLRW--LQQEEEERRHQELLQKKKEEEQER 674
Query: 330 LLEVMEEEELANLRASQREYEELRNSERAEVQRLE-----------EQERRHREE----- 373
L + E + LA R +R +E R ER E +R E EQERR +E
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734
Query: 374 ---KERRKK---QQWEIMHKHNETSQKIAARAFAQRYLAD 407
+ER K Q+ ++ + E +K + A+R L +
Sbjct: 735 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQE 774
Score = 29.3 bits (64), Expect = 10.0
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Query: 327 EQSLLEVMEEEELANLRASQREYEELRNSERAEVQRLE-------EQERRHREEKERRKK 379
EQ E E+ L +R E+ R E+Q E EQ +R EEK+++++
Sbjct: 704 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 763
Query: 380 QQWEIMHKHNETSQKIAARA 399
QQ + E +K A A
Sbjct: 764 QQRLAERQLQEEQEKKAKEA 783
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 42.4 bits (98), Expect = 0.001
Identities = 53/208 (25%), Positives = 91/208 (43%), Gaps = 30/208 (14%)
Query: 213 RPDSLELQRQREARKRALARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEV- 271
R D E +RQR R RK+ EQLR Q E + R+ +V+ L EE ++++
Sbjct: 527 RMDPKEKERQRLENLR---RKEEAEQLRRQKVEEDKRRRLEEVK--LKREERLRKVLQAR 581
Query: 272 ----DMECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIE 327
M+ + +++ I KT K ++ E + + K +E
Sbjct: 582 ERVEQMKEEKKKQIEQKFAQ--IDEKTEKAKEERLAE----------EKAKKKAAAKKME 629
Query: 328 QSLLEVMEEEELANLRASQREYEELRNSERAEVQRLEEQER--------RHREEKERRKK 379
+ +EEE LR Q+E EE R+ E + ++ EEQER R E++E+ ++
Sbjct: 630 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 689
Query: 380 QQWEIMHKHNETSQKIAARAFAQRYLAD 407
+Q + E ++ R +R LA+
Sbjct: 690 EQERREQERREQERREQERREQERQLAE 717
Score = 34.7 bits (78), Expect = 0.24
Identities = 53/220 (24%), Positives = 95/220 (43%), Gaps = 36/220 (16%)
Query: 213 RPDSLELQRQREARKRALARKQAQEQLRPQTPEPVEGR-KHVDVQTELYLEEIADRIIEV 271
R + ++L+R+ RK AR++ EQ++ + + +E + +D +TE EE R+ E
Sbjct: 562 RLEEVKLKREERLRKVLQARERV-EQMKEEKKKQIEQKFAQIDEKTEKAKEE---RLAEE 617
Query: 272 DMECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQS-- 329
+ + A + A+ ++ + L + E + E+L K E+
Sbjct: 618 KAKKKAAAKKMEE-----VEARRKQEEEARRLRW--LQQEEEERRHQELLQKKKEEEQER 670
Query: 330 LLEVMEEEELANLRASQREYEELRNSERAEVQRLE-----------EQERRHREEK---- 374
L + E + LA R +R +E R ER E +R E EQERR +E+
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
Query: 375 ----ERRKK---QQWEIMHKHNETSQKIAARAFAQRYLAD 407
ER K Q+ ++ + E +K + A+R L +
Sbjct: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQE 770
Score = 29.3 bits (64), Expect = 10.0
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Query: 327 EQSLLEVMEEEELANLRASQREYEELRNSERAEVQRLE-------EQERRHREEKERRKK 379
EQ E E+ L +R E+ R E+Q E EQ +R EEK+++++
Sbjct: 700 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 759
Query: 380 QQWEIMHKHNETSQKIAARA 399
QQ + E +K A A
Sbjct: 760 QQRLAERQLQEEQEKKAKEA 779
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 332 EVMEEEELANLRASQREYEELRNSERAEVQ-RLEEQERRHREEKERRKKQQWEIMHKHNE 390
E +E+E+L R + E L ER E Q RLE QER RE +ER+++++ E + + +
Sbjct: 184 ERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQ 243
Query: 391 TSQK 394
++
Sbjct: 244 ERER 247
Score = 34.3 bits (77), Expect = 0.31
Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 8/71 (11%)
Query: 332 EVMEEEELANLRASQ----REYEELRNSERAEVQ-RLEEQERRHREE---KERRKKQQWE 383
E +E E L R Q RE +E ER E Q RLE QER R+E +ER+++Q+ E
Sbjct: 174 ERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERE 233
Query: 384 IMHKHNETSQK 394
+ + Q+
Sbjct: 234 RLERLERERQE 244
Score = 33.5 bits (75), Expect = 0.53
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 5/69 (7%)
Query: 318 LEVLVGKTIEQSLLEVMEEEELANLRASQREYEELR-NSERAEVQRLE----EQERRHRE 372
LE+ + EQ + +E E L R + E R ER E +RLE E+ER+ RE
Sbjct: 140 LEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERE 199
Query: 373 EKERRKKQQ 381
+ER ++Q+
Sbjct: 200 RQERLERQE 208
Score = 32.3 bits (72), Expect = 1.2
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 9/90 (10%)
Query: 319 EVLVGKTIEQSLLEVMEEEELANLRASQRE----YEELRNSERAEVQRLEEQERRH--RE 372
E L + +EQ LE +E R ++E E L ER + +R E QER R
Sbjct: 179 ERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERL 238
Query: 373 EKERRKKQQWEIMHKHN---ETSQKIAARA 399
E+ER+++++ E + + E ++I++ A
Sbjct: 239 ERERQERERQEQLEREQLEWERERRISSAA 268
Score = 30.4 bits (67), Expect = 4.5
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 328 QSLLEVMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHK 387
Q LE+ + R + E E L ER E +RLE +ER RE ER + +Q ++ +
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLER-ERMERERLE-RERLERERLERERLEQEQLERE 194
Query: 388 HNETSQK 394
E ++
Sbjct: 195 RQERERQ 201
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 332 EVMEEEELANLRASQREYEELRNSERAEVQ-RLEEQERRHREEKERRKKQQWEIMHKHNE 390
E +E+E+L R + E L ER E Q RLE QER RE +ER+++++ E + + +
Sbjct: 184 ERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQ 243
Query: 391 TSQK 394
++
Sbjct: 244 ERER 247
Score = 34.3 bits (77), Expect = 0.31
Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 8/71 (11%)
Query: 332 EVMEEEELANLRASQ----REYEELRNSERAEVQ-RLEEQERRHREE---KERRKKQQWE 383
E +E E L R Q RE +E ER E Q RLE QER R+E +ER+++Q+ E
Sbjct: 174 ERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERE 233
Query: 384 IMHKHNETSQK 394
+ + Q+
Sbjct: 234 RLERLERERQE 244
Score = 33.5 bits (75), Expect = 0.53
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 5/69 (7%)
Query: 318 LEVLVGKTIEQSLLEVMEEEELANLRASQREYEELR-NSERAEVQRLE----EQERRHRE 372
LE+ + EQ + +E E L R + E R ER E +RLE E+ER+ RE
Sbjct: 140 LEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERE 199
Query: 373 EKERRKKQQ 381
+ER ++Q+
Sbjct: 200 RQERLERQE 208
Score = 32.3 bits (72), Expect = 1.2
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 9/90 (10%)
Query: 319 EVLVGKTIEQSLLEVMEEEELANLRASQRE----YEELRNSERAEVQRLEEQERRH--RE 372
E L + +EQ LE +E R ++E E L ER + +R E QER R
Sbjct: 179 ERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERL 238
Query: 373 EKERRKKQQWEIMHKHN---ETSQKIAARA 399
E+ER+++++ E + + E ++I++ A
Sbjct: 239 ERERQERERQEQLEREQLEWERERRISSAA 268
Score = 30.4 bits (67), Expect = 4.5
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 328 QSLLEVMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHK 387
Q LE+ + R + E E L ER E +RLE +ER RE ER + +Q ++ +
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLER-ERMERERLE-RERLERERLERERLEQEQLERE 194
Query: 388 HNETSQK 394
E ++
Sbjct: 195 RQERERQ 201
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 42.0 bits (97), Expect = 0.001
Identities = 48/169 (28%), Positives = 70/169 (41%), Gaps = 23/169 (13%)
Query: 236 QEQLRPQTPEPVEGRKHVDVQTELYLEEIA---DRIIEVDMECQTDAFLDRPPTPL-FIP 291
+E+ E E D + E EE D E E + + P P F+P
Sbjct: 13 EEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMP 72
Query: 292 AKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEV------MEEEELANL--- 342
V +I +GE DFD + +E + + Q+L+E EEEEL +L
Sbjct: 73 NL----VPPKIPDGERVDFDDIHRKRMEKDLNEL--QALIEAHFENRKKEEEELVSLKDR 126
Query: 343 ----RASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHK 387
RA + E + +RN E Q +ER REE+E R+K + E K
Sbjct: 127 IERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKK 175
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 42.0 bits (97), Expect = 0.001
Identities = 48/169 (28%), Positives = 70/169 (41%), Gaps = 23/169 (13%)
Query: 236 QEQLRPQTPEPVEGRKHVDVQTELYLEEIA---DRIIEVDMECQTDAFLDRPPTPL-FIP 291
+E+ E E D + E EE D E E + + P P F+P
Sbjct: 13 EEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMP 72
Query: 292 AKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEV------MEEEELANL--- 342
V +I +GE DFD + +E + + Q+L+E EEEEL +L
Sbjct: 73 NL----VPPKIPDGERVDFDDIHRKRMEKDLNEL--QALIEAHFENRKKEEEELVSLKDR 126
Query: 343 ----RASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHK 387
RA + E + +RN E Q +ER REE+E R+K + E K
Sbjct: 127 IERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKK 175
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 42.0 bits (97), Expect = 0.001
Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 335 EEEELANLRASQREYEE--LRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETS 392
+EEE LR Q E E+ R E + +R EE+ERR + E E ++KQ+ E K +
Sbjct: 919 QEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDE 978
Query: 393 QKIAARAFAQ 402
++I A AQ
Sbjct: 979 KRIQAEVEAQ 988
Score = 36.2 bits (82), Expect = 0.082
Identities = 20/68 (29%), Positives = 35/68 (51%)
Query: 327 EQSLLEVMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMH 386
E L EE L+ L+ +++ EE R + + +E++RR +EK RRK+++ M
Sbjct: 898 EYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMK 957
Query: 387 KHNETSQK 394
E +K
Sbjct: 958 LEMEAKRK 965
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 42.0 bits (97), Expect = 0.001
Identities = 19/48 (39%), Positives = 32/48 (66%)
Query: 334 MEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQ 381
+EE++ A +++ E R E+ E +RLEE ERR +EE+ERR+ ++
Sbjct: 409 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Query: 301 QILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNSERAEV 360
Q+L+ + E K L K IEQ ++E+ L QR E R + E
Sbjct: 374 QLLQEQQLREQEEYKRQLLAERQKRIEQ------QKEQRRRLEEQQRREREARRQQEREQ 427
Query: 361 QRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAARAFAQRYLAD 407
+R E++E+R EE ERR+K++ E E + + + +R L +
Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEE 474
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/49 (40%), Positives = 31/49 (63%)
Query: 346 QREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQK 394
+RE EE R E E +R EE+ERR EE++RR +++ E + + E Q+
Sbjct: 429 RREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQR 477
Score = 30.8 bits (68), Expect = 3.4
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 10/72 (13%)
Query: 327 EQSLLEVMEEEELANLRASQREYEELRNSE--RAEVQRLEEQERRHREEKERR------- 377
EQ E E+ L L ++E EE R +E + V+R +E RR EE++R
Sbjct: 426 EQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQ 485
Query: 378 -KKQQWEIMHKH 388
++Q ++H H
Sbjct: 486 LLQEQAMLLHDH 497
Score = 30.0 bits (66), Expect = 5.9
Identities = 21/79 (26%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 304 EGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEE--EELANLRASQR-EYEELRNSERAEV 360
E E+ + + E ++ V T+ + L + +E E LR Q + ++LR E +
Sbjct: 330 EEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKR 389
Query: 361 QRLEEQERRHREEKERRKK 379
Q L E+++R ++KE+R++
Sbjct: 390 QLLAERQKRIEQQKEQRRR 408
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 42.0 bits (97), Expect = 0.001
Identities = 19/48 (39%), Positives = 32/48 (66%)
Query: 334 MEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQ 381
+EE++ A +++ E R E+ E +RLEE ERR +EE+ERR+ ++
Sbjct: 409 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Query: 301 QILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNSERAEV 360
Q+L+ + E K L K IEQ ++E+ L QR E R + E
Sbjct: 374 QLLQEQQLREQEEYKRQLLAERQKRIEQ------QKEQRRRLEEQQRREREARRQQEREQ 427
Query: 361 QRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAARAFAQRYLAD 407
+R E++E+R EE ERR+K++ E E + + + +R L +
Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEE 474
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/49 (40%), Positives = 31/49 (63%)
Query: 346 QREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQK 394
+RE EE R E E +R EE+ERR EE++RR +++ E + + E Q+
Sbjct: 429 RREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQR 477
Score = 30.8 bits (68), Expect = 3.4
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 10/72 (13%)
Query: 327 EQSLLEVMEEEELANLRASQREYEELRNSE--RAEVQRLEEQERRHREEKERR------- 377
EQ E E+ L L ++E EE R +E + V+R +E RR EE++R
Sbjct: 426 EQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQ 485
Query: 378 -KKQQWEIMHKH 388
++Q ++H H
Sbjct: 486 LLQEQAMLLHDH 497
Score = 30.0 bits (66), Expect = 5.9
Identities = 21/79 (26%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 304 EGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEE--EELANLRASQR-EYEELRNSERAEV 360
E E+ + + E ++ V T+ + L + +E E LR Q + ++LR E +
Sbjct: 330 EEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKR 389
Query: 361 QRLEEQERRHREEKERRKK 379
Q L E+++R ++KE+R++
Sbjct: 390 QLLAERQKRIEQQKEQRRR 408
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 42.0 bits (97), Expect = 0.001
Identities = 19/48 (39%), Positives = 32/48 (66%)
Query: 334 MEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQ 381
+EE++ A +++ E R E+ E +RLEE ERR +EE+ERR+ ++
Sbjct: 409 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Query: 301 QILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNSERAEV 360
Q+L+ + E K L K IEQ ++E+ L QR E R + E
Sbjct: 374 QLLQEQQLREQEEYKRQLLAERQKRIEQ------QKEQRRRLEEQQRREREARRQQEREQ 427
Query: 361 QRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAARAFAQRYLAD 407
+R E++E+R EE ERR+K++ E E + + + +R L +
Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEE 474
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/49 (40%), Positives = 31/49 (63%)
Query: 346 QREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQK 394
+RE EE R E E +R EE+ERR EE++RR +++ E + + E Q+
Sbjct: 429 RREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQR 477
Score = 33.9 bits (76), Expect = 0.41
Identities = 42/196 (21%), Positives = 77/196 (39%), Gaps = 24/196 (12%)
Query: 213 RPDSLELQRQREARKRALARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVD 272
R D L LQ++ + R AL R+Q ++ + + E + + + Q + ++ R +E
Sbjct: 353 RRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQ 412
Query: 273 MECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLE 332
+ +A + E E + E K LE L + E+
Sbjct: 413 QRREREARRQQ--------------------EREQRRREQEEKRRLEELERRRKEEEERR 452
Query: 333 VMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETS 392
EEE+ R +RE E +R E + LE +++ +E+ + +W M +H +
Sbjct: 453 RAEEEK----RRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAE 508
Query: 393 QKIAARAFAQRYLADL 408
+ Q YL L
Sbjct: 509 RLQRQLQQEQAYLLSL 524
Score = 30.0 bits (66), Expect = 5.9
Identities = 21/79 (26%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 304 EGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEE--EELANLRASQR-EYEELRNSERAEV 360
E E+ + + E ++ V T+ + L + +E E LR Q + ++LR E +
Sbjct: 330 EEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKR 389
Query: 361 QRLEEQERRHREEKERRKK 379
Q L E+++R ++KE+R++
Sbjct: 390 QLLAERQKRIEQQKEQRRR 408
>gi|93102424 hypothetical protein LOC23116 [Homo sapiens]
Length = 1720
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 11/111 (9%)
Query: 291 PAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVM--EEEELANLRASQRE 348
PA + V + + G+ F ++P + G++++Q++ + E E+ A + S+
Sbjct: 1119 PATCSQSVISSVENGDTFSIKQSIEPPSGIY-GRSVQQNISSYLDVENEKDAKVSISKST 1177
Query: 349 YEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAARA 399
Y ++R +R EE+E H ++ E+++K WE M +H T +K+A+ +
Sbjct: 1178 YNKMRQ------KRKEEKELFHNKDCEKKEKNSWERM-RHTGT-EKMASES 1220
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/50 (44%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 335 EEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKER-RKKQQWE 383
E E R +RE E R+ ER QR E+ER H +KER R+K++WE
Sbjct: 405 ERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWE 454
Score = 29.3 bits (64), Expect = 10.0
Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 336 EEELANLRASQREYEELRNSERAEVQRLEEQERRHRE-EKERRKKQQWEIMHKHNETSQK 394
E E R +RE + E +R +E++RR E E+ER K+ + + H+ + ++
Sbjct: 416 ERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKE 475
Score = 29.3 bits (64), Expect = 10.0
Identities = 15/47 (31%), Positives = 25/47 (53%)
Query: 335 EEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQ 381
+ E R +RE E R+ ER + E+ER R+EK+R+ + +
Sbjct: 424 DRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDR 470
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 41.6 bits (96), Expect = 0.002
Identities = 60/246 (24%), Positives = 104/246 (42%), Gaps = 26/246 (10%)
Query: 321 LVGKTIEQSLLEVMEEEELANLRASQ--REYEELRNSERAEVQRLEEQERRHREEKERRK 378
L K ++LL+ MEE +L + A++ +E E L +R E++RLEE ER+ E ++
Sbjct: 211 LEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLK-QRWELERLEE-ERKQMEAFRQKA 268
Query: 379 KQQWEIMHKHN----ETSQKIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGF 434
+ + H++N +Q+I A R + L D R+ +
Sbjct: 269 ELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEK----EDESQRLHLARREQVMAD 324
Query: 435 LPWLMNEVEKTMEYSMVGRTVLDMLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMT 494
+ W+ +E+ ++ L ML+RE ++ M+E + E E +
Sbjct: 325 VAWMKQAIEEQLQLERAREAELQMLLREEAKE---MWE---------KREAEWARERSAR 372
Query: 495 ESLEASEFLEQSMSQTRELLLDGGYLQRTTYDRRSSQERKFMEERELLGQD-EETAMRKS 553
+ L SE L Q +E + Q + R R E REL ++ EE+ KS
Sbjct: 373 DRL-MSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKS 431
Query: 554 LGEEEL 559
++EL
Sbjct: 432 ARKQEL 437
Score = 30.8 bits (68), Expect = 3.4
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 17/114 (14%)
Query: 319 EVLVGKTIEQSLLEVME------EEELANLRASQREYEELRNSERAEVQRLEEQERRHRE 372
EVL G+ +Q + E +E EE L + R EE+R R E + E+ + ++
Sbjct: 378 EVLTGR--QQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQ 435
Query: 373 EKE----RRKKQQWEIMHKHNETSQKIAARAFAQRYLAD-LLPSVFGSLRDSGY 421
E E R+ Q WE + E ++ AR Q L+D LL ++ + GY
Sbjct: 436 ELEAQVAERRLQAWEADQQEEEEEEE--ARRVEQ--LSDALLQQEAETMAEQGY 485
Score = 29.3 bits (64), Expect = 10.0
Identities = 44/192 (22%), Positives = 79/192 (41%), Gaps = 26/192 (13%)
Query: 218 ELQRQREARKRALARKQAQEQ---LRPQTPEPVEGRKHVDVQTELYLEE-IADRIIEVDM 273
EL+R E RK+ A +Q E LR Q + R+ +Q EL + I ++E +
Sbjct: 250 ELERLEEERKQMEAFRQKAELGRFLRHQYNAQLS-RRTQQIQEELEADRRILQALLEKED 308
Query: 274 ECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEV 333
E Q R + DVA + + L+++ E + + + E+
Sbjct: 309 ESQRLHLARRE--------QVMADVAWM---KQAIEEQLQLERAREAELQMLLREEAKEM 357
Query: 334 MEEEELANLR---ASQREYEELRNSERAEVQ-------RLEEQERRHREEKERRKKQQWE 383
E+ E R A R E+ + ++Q R +E+ +HRE+ R ++ E
Sbjct: 358 WEKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRE 417
Query: 384 IMHKHNETSQKI 395
+ + E S+K+
Sbjct: 418 LARREKEESEKL 429
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 41.6 bits (96), Expect = 0.002
Identities = 60/246 (24%), Positives = 104/246 (42%), Gaps = 26/246 (10%)
Query: 321 LVGKTIEQSLLEVMEEEELANLRASQ--REYEELRNSERAEVQRLEEQERRHREEKERRK 378
L K ++LL+ MEE +L + A++ +E E L +R E++RLEE ER+ E ++
Sbjct: 211 LEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLK-QRWELERLEE-ERKQMEAFRQKA 268
Query: 379 KQQWEIMHKHN----ETSQKIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGF 434
+ + H++N +Q+I A R + L D R+ +
Sbjct: 269 ELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEK----EDESQRLHLARREQVMAD 324
Query: 435 LPWLMNEVEKTMEYSMVGRTVLDMLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMT 494
+ W+ +E+ ++ L ML+RE ++ M+E + E E +
Sbjct: 325 VAWMKQAIEEQLQLERAREAELQMLLREEAKE---MWE---------KREAEWARERSAR 372
Query: 495 ESLEASEFLEQSMSQTRELLLDGGYLQRTTYDRRSSQERKFMEERELLGQD-EETAMRKS 553
+ L SE L Q +E + Q + R R E REL ++ EE+ KS
Sbjct: 373 DRL-MSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKS 431
Query: 554 LGEEEL 559
++EL
Sbjct: 432 ARKQEL 437
Score = 30.8 bits (68), Expect = 3.4
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 17/114 (14%)
Query: 319 EVLVGKTIEQSLLEVME------EEELANLRASQREYEELRNSERAEVQRLEEQERRHRE 372
EVL G+ +Q + E +E EE L + R EE+R R E + E+ + ++
Sbjct: 378 EVLTGR--QQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQ 435
Query: 373 EKE----RRKKQQWEIMHKHNETSQKIAARAFAQRYLAD-LLPSVFGSLRDSGY 421
E E R+ Q WE + E ++ AR Q L+D LL ++ + GY
Sbjct: 436 ELEAQVAERRLQAWEADQQEEEEEEE--ARRVEQ--LSDALLQQEAETMAEQGY 485
Score = 29.3 bits (64), Expect = 10.0
Identities = 44/192 (22%), Positives = 79/192 (41%), Gaps = 26/192 (13%)
Query: 218 ELQRQREARKRALARKQAQEQ---LRPQTPEPVEGRKHVDVQTELYLEE-IADRIIEVDM 273
EL+R E RK+ A +Q E LR Q + R+ +Q EL + I ++E +
Sbjct: 250 ELERLEEERKQMEAFRQKAELGRFLRHQYNAQLS-RRTQQIQEELEADRRILQALLEKED 308
Query: 274 ECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEV 333
E Q R + DVA + + L+++ E + + + E+
Sbjct: 309 ESQRLHLARRE--------QVMADVAWM---KQAIEEQLQLERAREAELQMLLREEAKEM 357
Query: 334 MEEEELANLR---ASQREYEELRNSERAEVQ-------RLEEQERRHREEKERRKKQQWE 383
E+ E R A R E+ + ++Q R +E+ +HRE+ R ++ E
Sbjct: 358 WEKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRE 417
Query: 384 IMHKHNETSQKI 395
+ + E S+K+
Sbjct: 418 LARREKEESEKL 429
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 40.8 bits (94), Expect = 0.003
Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 6/109 (5%)
Query: 302 ILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNSERAEVQ 361
+LE E + ++ E + E+ LE +E+ A L ++E E L ERAE +
Sbjct: 334 VLEDEQQQLEKKLPVTFEDKKRENFERGNLE-LEKRRQALLEQQRKEQERLAQLERAEQE 392
Query: 362 RLE----EQERRHREEKERRKKQQWEIMHKHNETSQK-IAARAFAQRYL 405
R E EQER+ + E E++ ++Q E+ + E +K I R A+R L
Sbjct: 393 RKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKREL 441
Score = 38.1 bits (87), Expect = 0.022
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 26/150 (17%)
Query: 253 VDVQTELYLEE--IADRIIEVDMECQTDAFLDRPPT--PLFIP-----AKTGKDVATQIL 303
+D +L EE +A +I+V M Q PP P +IP ++G ++ ++
Sbjct: 268 IDQDGKLTAEEFILAMHLIDVAMSGQP-----LPPVLPPEYIPPSFRRVRSGSGIS--VI 320
Query: 304 EGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNS----ERAE 359
D L +PVLE + +E+ L E+++ N E E+ R + +R E
Sbjct: 321 SSTSVDQRLPEEPVLED-EQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKE 379
Query: 360 VQRLE-----EQERRHREEKERRKKQQWEI 384
+RL EQER+ RE +E+ +K+Q E+
Sbjct: 380 QERLAQLERAEQERKERERQEQERKRQLEL 409
Score = 32.7 bits (73), Expect = 0.90
Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 15/90 (16%)
Query: 319 EVLVGKTIEQSLLEVMEEEELANLRASQREYEELRN----SERAEVQRLEEQERRHREEK 374
E L K E+ ++E+ +++E A RA +R+ + L + E ++L E+E+ REE
Sbjct: 628 ERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREES 687
Query: 375 ------ERRKKQQWE-----IMHKHNETSQ 393
E + KQ+ + + H+H E ++
Sbjct: 688 VKKKDGEEKGKQEAQDKLGRLFHQHQEPAK 717
Score = 30.0 bits (66), Expect = 5.9
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 25/92 (27%)
Query: 328 QSLLEVM--EEEELANLRASQREYEELRNSERA---------------EVQRLEEQERRH 370
Q+LLE E+E LA L +++E +E E+ E++R E+ERR
Sbjct: 370 QALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRK 429
Query: 371 --------REEKERRKKQQWEIMHKHNETSQK 394
+ E ER+++ +WE + +Q+
Sbjct: 430 EIERREAAKRELERQRQLEWERNRRQELLNQR 461
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 40.8 bits (94), Expect = 0.003
Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 6/109 (5%)
Query: 302 ILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNSERAEVQ 361
+LE E + ++ E + E+ LE +E+ A L ++E E L ERAE +
Sbjct: 334 VLEDEQQQLEKKLPVTFEDKKRENFERGNLE-LEKRRQALLEQQRKEQERLAQLERAEQE 392
Query: 362 RLE----EQERRHREEKERRKKQQWEIMHKHNETSQK-IAARAFAQRYL 405
R E EQER+ + E E++ ++Q E+ + E +K I R A+R L
Sbjct: 393 RKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKREL 441
Score = 38.1 bits (87), Expect = 0.022
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 26/150 (17%)
Query: 253 VDVQTELYLEE--IADRIIEVDMECQTDAFLDRPPT--PLFIP-----AKTGKDVATQIL 303
+D +L EE +A +I+V M Q PP P +IP ++G ++ ++
Sbjct: 268 IDQDGKLTAEEFILAMHLIDVAMSGQP-----LPPVLPPEYIPPSFRRVRSGSGIS--VI 320
Query: 304 EGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNS----ERAE 359
D L +PVLE + +E+ L E+++ N E E+ R + +R E
Sbjct: 321 SSTSVDQRLPEEPVLED-EQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKE 379
Query: 360 VQRLE-----EQERRHREEKERRKKQQWEI 384
+RL EQER+ RE +E+ +K+Q E+
Sbjct: 380 QERLAQLERAEQERKERERQEQERKRQLEL 409
Score = 32.7 bits (73), Expect = 0.90
Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 15/90 (16%)
Query: 319 EVLVGKTIEQSLLEVMEEEELANLRASQREYEELRN----SERAEVQRLEEQERRHREEK 374
E L K E+ ++E+ +++E A RA +R+ + L + E ++L E+E+ REE
Sbjct: 628 ERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREES 687
Query: 375 ------ERRKKQQWE-----IMHKHNETSQ 393
E + KQ+ + + H+H E ++
Sbjct: 688 VKKKDGEEKGKQEAQDKLGRLFHQHQEPAK 717
Score = 30.0 bits (66), Expect = 5.9
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 25/92 (27%)
Query: 328 QSLLEVM--EEEELANLRASQREYEELRNSERA---------------EVQRLEEQERRH 370
Q+LLE E+E LA L +++E +E E+ E++R E+ERR
Sbjct: 370 QALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRK 429
Query: 371 --------REEKERRKKQQWEIMHKHNETSQK 394
+ E ER+++ +WE + +Q+
Sbjct: 430 EIERREAAKRELERQRQLEWERNRRQELLNQR 461
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 40.8 bits (94), Expect = 0.003
Identities = 47/203 (23%), Positives = 88/203 (43%), Gaps = 20/203 (9%)
Query: 218 ELQRQREARKRALARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMECQT 277
E + Q + + A+ +KQ +E+ T + K + + EEI D I+ D E +
Sbjct: 420 EKKAQEDKLQTAVLKKQGEEK---GTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 476
Query: 278 D--AFLDRPPTPLFIPAKTGKDVATQILE---------GELFDFDLEVKPVLEVLVGKTI 326
+ +F+DR + ++ G+ + ++ G E + +V GK +
Sbjct: 477 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRL 536
Query: 327 EQSLLE--VMEEEELANLRASQRE----YEELRNSERAEVQRLEEQERRHREEKERRKKQ 380
E+ E EE L+ Q+E EEL+ + LEE+E+R ++E+ RK +
Sbjct: 537 EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLR 596
Query: 381 QWEIMHKHNETSQKIAARAFAQR 403
+ E + E ++ A A +R
Sbjct: 597 EEEEKRRLKEEIERRRAEAAEKR 619
Score = 32.7 bits (73), Expect = 0.90
Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 332 EVMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQ 381
E M EEE QR EE + + E QR++E+E+R EE++R K+++
Sbjct: 315 ERMREEEKRAAEERQRIKEEEKRAAE-ERQRIKEEEKRAAEERQRIKEEE 363
Score = 32.7 bits (73), Expect = 0.90
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 333 VMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETS 392
+ EEE+ A + + EE R +E + R EE+E+ EE ++R KQ E H ET
Sbjct: 345 IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEE-QKRNKQLEEKKHAMQETK 403
Query: 393 QK 394
K
Sbjct: 404 IK 405
Score = 32.0 bits (71), Expect = 1.5
Identities = 46/190 (24%), Positives = 78/190 (41%), Gaps = 24/190 (12%)
Query: 220 QRQREARKRALARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMECQTDA 279
+R+R AR+ L +KQ +E L Q + VE V E + +E D E A
Sbjct: 40 ERRRRARQERLRQKQEEESL-GQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEA---A 95
Query: 280 FLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLL--EVMEEE 337
FL+R L + + + LE + +FD + L + ++ E E+E
Sbjct: 96 FLER----LARREERRQKRLQEALERQK-EFDPTITDASLSLPSRRMQNDTAENETTEKE 150
Query: 338 ELANLRASQREYEEL--------RNSERAEVQRLEEQERRHREEKERRKK-----QQWEI 384
E + R + E EE +N R + +E + + EE+E+ K+ Q E+
Sbjct: 151 EKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEV 210
Query: 385 MHKHNETSQK 394
M + T +
Sbjct: 211 MVEEKTTESQ 220
Score = 32.0 bits (71), Expect = 1.5
Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Query: 333 VMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWE 383
+ EEE+ A + + EE R +E E QR++E+E+R EE++R + ++ E
Sbjct: 331 IKEEEKRAAEERQRIKEEEKRAAE--ERQRIKEEEKRAAEERQRARAEEEE 379
Score = 30.8 bits (68), Expect = 3.4
Identities = 20/78 (25%), Positives = 33/78 (42%)
Query: 304 EGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNSERAEVQRL 363
E E + E + ++ K I + EE+ A +RE EE E +
Sbjct: 266 EAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAA 325
Query: 364 EEQERRHREEKERRKKQQ 381
EE++R EEK +++Q
Sbjct: 326 EERQRIKEEEKRAAEERQ 343
Score = 30.4 bits (67), Expect = 4.5
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 9/68 (13%)
Query: 332 EVMEEE-------ELANLRASQREYEELRNSERA--EVQRLEEQERRHREEKERRKKQQW 382
E MEEE E A L A +RE + ++ E R+E +E+ +E+ERR+ ++
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314
Query: 383 EIMHKHNE 390
E M + +
Sbjct: 315 ERMREEEK 322
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,539,884
Number of Sequences: 37866
Number of extensions: 1327018
Number of successful extensions: 12929
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 247
Number of HSP's successfully gapped in prelim test: 434
Number of HSP's that attempted gapping in prelim test: 7613
Number of HSP's gapped (non-prelim): 3585
length of query: 560
length of database: 18,247,518
effective HSP length: 107
effective length of query: 453
effective length of database: 14,195,856
effective search space: 6430722768
effective search space used: 6430722768
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.