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Search of human proteins with 31542845
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
(515 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] 1062 0.0
gi|14211941 gap junction protein, alpha 10 [Homo sapiens] 363 e-100
gi|22779877 connexin 46 [Homo sapiens] 284 2e-76
gi|55953076 connexin 50 [Homo sapiens] 282 6e-76
gi|32483412 connexin 40 [Homo sapiens] 276 4e-74
gi|6631083 connexin 40 [Homo sapiens] 276 4e-74
gi|62865885 connexin 37 [Homo sapiens] 264 2e-70
gi|4504001 connexin 43 [Homo sapiens] 245 6e-65
gi|122939172 connexin 45 [Homo sapiens] 223 3e-58
gi|69122473 connexin 45 [Homo sapiens] 223 3e-58
gi|42558283 gap junction protein beta 2 [Homo sapiens] 213 3e-55
gi|159032020 gap junction protein, beta 6 [Homo sapiens] 205 7e-53
gi|158966714 gap junction protein, beta 6 [Homo sapiens] 205 7e-53
gi|158966717 gap junction protein, beta 6 [Homo sapiens] 205 7e-53
gi|40254837 gap junction protein, beta 6 [Homo sapiens] 205 7e-53
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] 192 5e-49
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] 192 5e-49
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] 190 2e-48
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] 180 3e-45
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 176 3e-44
gi|54607056 connexin 31 [Homo sapiens] 173 3e-43
gi|13128960 connexin 31 [Homo sapiens] 173 3e-43
gi|23397464 gap junction protein, beta 4 [Homo sapiens] 173 4e-43
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] 172 5e-43
gi|145699105 connexin40.1 [Homo sapiens] 140 2e-33
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 132 8e-31
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] 130 2e-30
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] 91 3e-18
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] 91 3e-18
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] 91 3e-18
>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
Length = 515
Score = 1062 bits (2746), Expect = 0.0
Identities = 515/515 (100%), Positives = 515/515 (100%)
Query: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
Sbjct: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
Query: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE
Sbjct: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
Query: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG
Sbjct: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
Query: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR
Sbjct: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
Query: 241 GLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPSL 300
GLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPSL
Sbjct: 241 GLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPSL 300
Query: 301 NSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIFGK 360
NSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIFGK
Sbjct: 301 NSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIFGK 360
Query: 361 ELNGNQLMEKRETEGKDSKRNYYSRGHRSIPGVAIDGENNMRQSPQTVFSLPANCDWKPR 420
ELNGNQLMEKRETEGKDSKRNYYSRGHRSIPGVAIDGENNMRQSPQTVFSLPANCDWKPR
Sbjct: 361 ELNGNQLMEKRETEGKDSKRNYYSRGHRSIPGVAIDGENNMRQSPQTVFSLPANCDWKPR 420
Query: 421 WLRATWGSSTEHENRGSPPKGNLKGQFRKGTVRTLPPSQGDSQSLDIPNTADSLGGLSFE 480
WLRATWGSSTEHENRGSPPKGNLKGQFRKGTVRTLPPSQGDSQSLDIPNTADSLGGLSFE
Sbjct: 421 WLRATWGSSTEHENRGSPPKGNLKGQFRKGTVRTLPPSQGDSQSLDIPNTADSLGGLSFE 480
Query: 481 PGLVRTCNNPVCPPNHVVSLTNNLIGRRVPTDLQI 515
PGLVRTCNNPVCPPNHVVSLTNNLIGRRVPTDLQI
Sbjct: 481 PGLVRTCNNPVCPPNHVVSLTNNLIGRRVPTDLQI 515
>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
Length = 543
Score = 363 bits (933), Expect = e-100
Identities = 177/264 (67%), Positives = 214/264 (81%), Gaps = 6/264 (2%)
Query: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
MGDWNLLG LEEVH HST++GKIWLTILFIFRMLVL VAAEDVW+DEQS F CNT QPG
Sbjct: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
Query: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
C N+CYD AFPISLIR+WVLQ+IFVSSPSLVYMGHALYRLR E++RQR K+ LR ++E
Sbjct: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120
Query: 121 VEFEMPRDRRRLEQELCQLEKRK-LNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY 179
+ ++ +++R+++EL +LE++K ++K PL+G LL TYV+HI TRSV+EVGFMIGQY+LY
Sbjct: 121 PDLDL-EEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY 179
Query: 180 GFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIK 239
GF + PL+KC PCPN +DCFVSRPTEKTIF+LFM SIA ISL LNILEIFHLG +KI
Sbjct: 180 GFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIM 239
Query: 240 RGLWGKYKLKKEHNE----FHANK 259
R L+ K + +E FH K
Sbjct: 240 RTLYKKSSSEGIEDETGPPFHLKK 263
>gi|22779877 connexin 46 [Homo sapiens]
Length = 435
Score = 284 bits (726), Expect = 2e-76
Identities = 132/242 (54%), Positives = 180/242 (74%), Gaps = 8/242 (3%)
Query: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
MGDW+ LG LE HST+IGK+WLT+LFIFR+LVLG AAEDVW DEQS F CNT+QPG
Sbjct: 1 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG 60
Query: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
C NVCYD+AFPIS IR+W LQ+IFVS+P+L+Y+GH L+ +R+ E++++ R E E+
Sbjct: 61 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKE------REEEEQ 114
Query: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
++ E P + + + R + + G LL TYV +I +++ EVGF+ GQY LYG
Sbjct: 115 LKRESPSPKEPPQDNPSSRDDR--GRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYG 172
Query: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
F L+PL++C PCPN +DCF+SRPTEKTIF++FM ++A SL LN+LEI+HLG+KK+K+
Sbjct: 173 FELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQ 232
Query: 241 GL 242
G+
Sbjct: 233 GV 234
>gi|55953076 connexin 50 [Homo sapiens]
Length = 433
Score = 282 bits (721), Expect = 6e-76
Identities = 132/242 (54%), Positives = 181/242 (74%), Gaps = 6/242 (2%)
Query: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
MGDW+ LG+ LEEV+ HST+IG++WLT+LFIFR+L+LG AAE VW DEQS F+CNT+QPG
Sbjct: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
Query: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
C NVCYD+AFPIS IR WVLQ+IFVS+PSL+Y+GHA++ +R+ E+ + R +L ++
Sbjct: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELG---QQ 117
Query: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
D+ +++ +K L GTLL TY+ HI +++ EVGF++G Y LYG
Sbjct: 118 AGTNGGPDQGSVKKSSGSKGTKKFR---LEGTLLRTYICHIIFKTLFEVGFIVGHYFLYG 174
Query: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
F + PL++C PCPN++DCFVSRPTEKTIF+LFM S+A++SLFLN++E+ HLG K I+
Sbjct: 175 FRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRS 234
Query: 241 GL 242
L
Sbjct: 235 AL 236
>gi|32483412 connexin 40 [Homo sapiens]
Length = 358
Score = 276 bits (705), Expect = 4e-74
Identities = 143/314 (45%), Positives = 200/314 (63%), Gaps = 21/314 (6%)
Query: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
MGDW+ LG+ LEEVH HST++GK+WLT+LFIFRMLVLG AAE W DEQ+ F C+T QPG
Sbjct: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
Query: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
C+NVCYDQAFPIS IRYWVLQ+IFVS+PSLVYMGHA++ +R+ E+ + R + +
Sbjct: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
Query: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
+E P + EL E+ + L+GTLL TYV I R+ +EVGF++GQY +YG
Sbjct: 121 GSYEYPVAEK---AELSCWEEGN-GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
Query: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
L L C PCP+ ++C+VSRPTEK +F++FM ++A +SL L++ E++HLG+KKI++
Sbjct: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
Query: 241 GLWGKYKLKKEHNEFHANKAKQNVAKYQ--STSANSLKRLPSAPDYNLLVEKQTHTAVYP 298
K +Q++AK Q S ++ PD+N +E +
Sbjct: 237 ---------------RFVKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFN 281
Query: 299 SLNSSSVFQPNPDN 312
+++ Q N DN
Sbjct: 282 PFSNNMASQQNTDN 295
>gi|6631083 connexin 40 [Homo sapiens]
Length = 358
Score = 276 bits (705), Expect = 4e-74
Identities = 143/314 (45%), Positives = 200/314 (63%), Gaps = 21/314 (6%)
Query: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
MGDW+ LG+ LEEVH HST++GK+WLT+LFIFRMLVLG AAE W DEQ+ F C+T QPG
Sbjct: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
Query: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
C+NVCYDQAFPIS IRYWVLQ+IFVS+PSLVYMGHA++ +R+ E+ + R + +
Sbjct: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
Query: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
+E P + EL E+ + L+GTLL TYV I R+ +EVGF++GQY +YG
Sbjct: 121 GSYEYPVAEK---AELSCWEEGN-GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
Query: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
L L C PCP+ ++C+VSRPTEK +F++FM ++A +SL L++ E++HLG+KKI++
Sbjct: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
Query: 241 GLWGKYKLKKEHNEFHANKAKQNVAKYQ--STSANSLKRLPSAPDYNLLVEKQTHTAVYP 298
K +Q++AK Q S ++ PD+N +E +
Sbjct: 237 ---------------RFVKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFN 281
Query: 299 SLNSSSVFQPNPDN 312
+++ Q N DN
Sbjct: 282 PFSNNMASQQNTDN 295
>gi|62865885 connexin 37 [Homo sapiens]
Length = 333
Score = 264 bits (674), Expect = 2e-70
Identities = 126/242 (52%), Positives = 170/242 (70%), Gaps = 2/242 (0%)
Query: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
MGDW L L++V HST++GKIWLT+LFIFR+L+LG+A E VW DEQS F CNT QPG
Sbjct: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
Query: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
C NVCYDQAFPIS IRYWVLQ +FVS+P+LVY+GH +Y R EER R K L
Sbjct: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSR--REERLRQKEGELRALPA 118
Query: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
+ ++ R +E+++ ++ + + +RG L+ TYV + +SV+E GF+ GQ+ LYG
Sbjct: 119 KDPQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYG 178
Query: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
+ +EP+F C PCP ++DCFVSRPTEKTIF++FM + ISL LN+LE+ HL + + R
Sbjct: 179 WTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSR 238
Query: 241 GL 242
G+
Sbjct: 239 GM 240
>gi|4504001 connexin 43 [Homo sapiens]
Length = 382
Score = 245 bits (626), Expect = 6e-65
Identities = 139/389 (35%), Positives = 220/389 (56%), Gaps = 29/389 (7%)
Query: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
MGDW+ LG L++V +ST GK+WL++LFIFR+L+LG A E W DEQS F CNT+QPG
Sbjct: 1 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG 60
Query: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRV-ELE 119
C NVCYD++FPIS +R+WVLQ+IFVS P+L+Y+ H Y +R EE+ + + +L+V + +
Sbjct: 61 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMR-KEEKLNKKEEELKVAQTD 119
Query: 120 EVEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY 179
V +M + +++ +E+ K +RG LL TY+I I +S+ EV F++ Q+ +Y
Sbjct: 120 GVNVDMHLKQIEIKKFKYGIEEH--GKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIY 177
Query: 180 GFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIK 239
GF L ++ C PCP+ +DCF+SRPTEKTIF++FM ++ +SL LNI+E+F++ FK +K
Sbjct: 178 GFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVK 237
Query: 240 RGLWGKYKLKKEHNEFHANK---------AKQNVAKYQSTSANSLKRLPSAPDYNLLVEK 290
++K + + +HA Q A + S+ + P +P LV
Sbjct: 238 D------RVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTG 291
Query: 291 QTHTAVYPSLNSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNN 350
+ + + N + Q N N+S + + ST+S S + +N
Sbjct: 292 DRNNSSCRNYNKQASEQ-NWANYSAEQNR---------MGQAGSTISNSHAQPFDFPDDN 341
Query: 351 NKDTHKIFGKELNGNQLMEKRETEGKDSK 379
G EL ++++R + S+
Sbjct: 342 QNSKKLAAGHELQPLAIVDQRPSSRASSR 370
>gi|122939172 connexin 45 [Homo sapiens]
Length = 396
Score = 223 bits (568), Expect = 3e-58
Identities = 113/263 (42%), Positives = 156/263 (59%), Gaps = 21/263 (7%)
Query: 4 WNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRN 63
W+ L LEE+H HST +GKIWLT+L +FR+++ V E ++ DEQS F+CNTEQPGC N
Sbjct: 3 WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62
Query: 64 VCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKA----------- 112
VCYD P+S +R+WV Q+I V++PS++Y+G+A++++ +E KA
Sbjct: 63 VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122
Query: 113 --QLRVELEEVEFEMPRDRRRLEQELCQLEKRKLNKAP--------LRGTLLCTYVIHIF 162
+ E EE E P +E E + K + P L+ YV+ +
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLL 182
Query: 163 TRSVVEVGFMIGQYLLYGFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATIS 222
R+V EVGF+IGQY LYGF + P + C PCP+ IDCF+SRPTEKTIFLL M + +
Sbjct: 183 ARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLC 242
Query: 223 LFLNILEIFHLGFKKIKRGLWGK 245
L LNI E+ HLGF I+ L K
Sbjct: 243 LLLNIWEMLHLGFGTIRDSLNSK 265
>gi|69122473 connexin 45 [Homo sapiens]
Length = 396
Score = 223 bits (568), Expect = 3e-58
Identities = 113/263 (42%), Positives = 156/263 (59%), Gaps = 21/263 (7%)
Query: 4 WNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRN 63
W+ L LEE+H HST +GKIWLT+L +FR+++ V E ++ DEQS F+CNTEQPGC N
Sbjct: 3 WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62
Query: 64 VCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKA----------- 112
VCYD P+S +R+WV Q+I V++PS++Y+G+A++++ +E KA
Sbjct: 63 VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122
Query: 113 --QLRVELEEVEFEMPRDRRRLEQELCQLEKRKLNKAP--------LRGTLLCTYVIHIF 162
+ E EE E P +E E + K + P L+ YV+ +
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLL 182
Query: 163 TRSVVEVGFMIGQYLLYGFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATIS 222
R+V EVGF+IGQY LYGF + P + C PCP+ IDCF+SRPTEKTIFLL M + +
Sbjct: 183 ARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLC 242
Query: 223 LFLNILEIFHLGFKKIKRGLWGK 245
L LNI E+ HLGF I+ L K
Sbjct: 243 LLLNIWEMLHLGFGTIRDSLNSK 265
>gi|42558283 gap junction protein beta 2 [Homo sapiens]
Length = 226
Score = 213 bits (543), Expect = 3e-55
Identities = 107/232 (46%), Positives = 150/232 (64%), Gaps = 21/232 (9%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
DW L L V+ HST IGKIWLT+LFIFR+++L VAA++VW DEQ+ F+CNT QPGC+
Sbjct: 2 DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
NVCYD FPIS IR W LQ+IFVS+P+L+ H YR E++R+ +K +++ E +++
Sbjct: 62 NVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRH--EKKRKFIKGEIKSEFKDI- 118
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181
E+ K K + G+L TY IF R + E FM Y++Y GF
Sbjct: 119 -----------------EEIKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGF 161
Query: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHL 233
++ L KC+ PCPN +DCFVSRPTEKT+F +FM +++ I + LN+ E+ +L
Sbjct: 162 SMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYL 213
>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 205 bits (522), Expect = 7e-53
Identities = 109/266 (40%), Positives = 159/266 (59%), Gaps = 30/266 (11%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
DW L + V+ HST IGK+W+T++FIFR+++L VAA++VW DEQ F+CNT QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
NVCYD FP+S IR W LQ+IFVS+P+L+ H Y E R+ + + R + +++E
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRH--ETTRKFRRGEKRNDFKDIE 119
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181
++K+K+ + G+L TY IF R + E FM Y LY G+
Sbjct: 120 ---------------DIKKQKVR---IEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGY 161
Query: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHL----GFKK 237
HL + KC PCPN++DCF+SRPTEKT+F +FM S + I + LN+ E+ +L F++
Sbjct: 162 HLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRR 221
Query: 238 IKRGLWGKYKLKKEHNEFHANKAKQN 263
KR + +K H ++KQN
Sbjct: 222 SKRA-----QTQKNHPNHALKESKQN 242
>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 205 bits (522), Expect = 7e-53
Identities = 109/266 (40%), Positives = 159/266 (59%), Gaps = 30/266 (11%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
DW L + V+ HST IGK+W+T++FIFR+++L VAA++VW DEQ F+CNT QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
NVCYD FP+S IR W LQ+IFVS+P+L+ H Y E R+ + + R + +++E
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRH--ETTRKFRRGEKRNDFKDIE 119
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181
++K+K+ + G+L TY IF R + E FM Y LY G+
Sbjct: 120 ---------------DIKKQKVR---IEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGY 161
Query: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHL----GFKK 237
HL + KC PCPN++DCF+SRPTEKT+F +FM S + I + LN+ E+ +L F++
Sbjct: 162 HLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRR 221
Query: 238 IKRGLWGKYKLKKEHNEFHANKAKQN 263
KR + +K H ++KQN
Sbjct: 222 SKRA-----QTQKNHPNHALKESKQN 242
>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 205 bits (522), Expect = 7e-53
Identities = 109/266 (40%), Positives = 159/266 (59%), Gaps = 30/266 (11%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
DW L + V+ HST IGK+W+T++FIFR+++L VAA++VW DEQ F+CNT QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
NVCYD FP+S IR W LQ+IFVS+P+L+ H Y E R+ + + R + +++E
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRH--ETTRKFRRGEKRNDFKDIE 119
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181
++K+K+ + G+L TY IF R + E FM Y LY G+
Sbjct: 120 ---------------DIKKQKVR---IEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGY 161
Query: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHL----GFKK 237
HL + KC PCPN++DCF+SRPTEKT+F +FM S + I + LN+ E+ +L F++
Sbjct: 162 HLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRR 221
Query: 238 IKRGLWGKYKLKKEHNEFHANKAKQN 263
KR + +K H ++KQN
Sbjct: 222 SKRA-----QTQKNHPNHALKESKQN 242
>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 205 bits (522), Expect = 7e-53
Identities = 109/266 (40%), Positives = 159/266 (59%), Gaps = 30/266 (11%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
DW L + V+ HST IGK+W+T++FIFR+++L VAA++VW DEQ F+CNT QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
NVCYD FP+S IR W LQ+IFVS+P+L+ H Y E R+ + + R + +++E
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRH--ETTRKFRRGEKRNDFKDIE 119
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181
++K+K+ + G+L TY IF R + E FM Y LY G+
Sbjct: 120 ---------------DIKKQKVR---IEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGY 161
Query: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHL----GFKK 237
HL + KC PCPN++DCF+SRPTEKT+F +FM S + I + LN+ E+ +L F++
Sbjct: 162 HLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRR 221
Query: 238 IKRGLWGKYKLKKEHNEFHANKAKQN 263
KR + +K H ++KQN
Sbjct: 222 SKRA-----QTQKNHPNHALKESKQN 242
>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 192 bits (489), Expect = 5e-49
Identities = 104/232 (44%), Positives = 142/232 (61%), Gaps = 22/232 (9%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
+W L L V+ HST IG++WL+++FIFR++VL VAAE VW DE+S FICNT QPGC
Sbjct: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
+VCYDQ FPIS +R W LQ+I VS+P+L+ H ++ + K LR+E
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHI-------EKKMLRLE----- 109
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181
+ LE+ K +K + GTL TYVI + R + E FM YLLY G+
Sbjct: 110 ---------GHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGY 160
Query: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHL 233
+ L KC +PCPN +DCFVSRPTEKT+F +FM + + I + LN+ E+ +L
Sbjct: 161 AMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212
>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 192 bits (489), Expect = 5e-49
Identities = 104/232 (44%), Positives = 142/232 (61%), Gaps = 22/232 (9%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
+W L L V+ HST IG++WL+++FIFR++VL VAAE VW DE+S FICNT QPGC
Sbjct: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
+VCYDQ FPIS +R W LQ+I VS+P+L+ H ++ + K LR+E
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHI-------EKKMLRLE----- 109
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181
+ LE+ K +K + GTL TYVI + R + E FM YLLY G+
Sbjct: 110 ---------GHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGY 160
Query: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHL 233
+ L KC +PCPN +DCFVSRPTEKT+F +FM + + I + LN+ E+ +L
Sbjct: 161 AMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212
>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
Length = 321
Score = 190 bits (483), Expect = 2e-48
Identities = 106/295 (35%), Positives = 173/295 (58%), Gaps = 48/295 (16%)
Query: 1 MGDWNLLGDTLEE-VHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQP 59
MG+W +L LE V HSTMIG+I LT++ IFR+L++ + E V++DEQ+ F+CNT QP
Sbjct: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
Query: 60 GCRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELE 119
GC CYD+AFPIS IRYWV Q+I V +PSL ++ +++++ ++R+R + + + L+
Sbjct: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQ---SAKQRERRYSTVFLALD 117
Query: 120 EVEFEM---------------PRDRRRLEQELCQ-----------------LEKRKL--- 144
E R+ ++L+ + LE ++L
Sbjct: 118 RDPPESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPH 177
Query: 145 -------NKAPLRGT--LLCTYVIHIFTRSVVEVGFMIGQYLLYGFHLEPLFKCHGHPCP 195
+K+ LR + Y+I + R+ +E+GF++GQY LYGF + L++C+ +PC
Sbjct: 178 PSGLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCI 237
Query: 196 NIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKRGLWGKYKLKK 250
++C+VSRPTEKT+FL+FM +++ I + LN+ E+ HLG++KIK + G +K
Sbjct: 238 KEVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRK 292
>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
Length = 294
Score = 180 bits (456), Expect = 3e-45
Identities = 91/254 (35%), Positives = 142/254 (55%), Gaps = 21/254 (8%)
Query: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
MG+W LG L+ V + S ++G++WL ++ IFR+LVL V+ DEQ F+CNT QPG
Sbjct: 1 MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
Query: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
CR CYD+AFP+S R+W+ ++ +S+P ++++ ++++R E AQ L E
Sbjct: 61 CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAG-KEAGGAEAAAQCAPGLPE 119
Query: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
+ C L R+ + Y++ + R + E+ F+ GQ LLYG
Sbjct: 120 AQCAP-----------CALRARRARRC---------YLLSVALRLLAELTFLGGQALLYG 159
Query: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
F + P F C G PCP+ +DCFVSRPTEKT+F+LF ++ +S L++ E+ HL +K R
Sbjct: 160 FRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPR 219
Query: 241 GLWGKYKLKKEHNE 254
+ + H E
Sbjct: 220 AGERDNRCNRAHEE 233
>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
Length = 273
Score = 176 bits (447), Expect = 3e-44
Identities = 93/239 (38%), Positives = 138/239 (57%), Gaps = 32/239 (13%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
+W++ L V+ +ST G+IWL+++FIFR+LV V AE VW+D+ F CNT QPGC
Sbjct: 2 NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
NVC+D+ FP+S +R W LQ+I V+ PSL+ + H YR EV+
Sbjct: 62 NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR--------------------EVQ 101
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYGFH 182
++R E + LN RG L TYV + ++ V++ F+ Y+ + F+
Sbjct: 102 -----EKRHREAHGENSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFL---YVFHSFY 153
Query: 183 ----LEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKK 237
L P+ KCH PCPNI+DCF+S+P+EK IF LFM + A I + LN++E+ +L K+
Sbjct: 154 PKYILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKR 212
>gi|54607056 connexin 31 [Homo sapiens]
Length = 270
Score = 173 bits (439), Expect = 3e-43
Identities = 98/242 (40%), Positives = 137/242 (56%), Gaps = 27/242 (11%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
DW L L V+ +ST G+IWL+++F+FR+LV VAAE VW DEQ F CNT+QPGC
Sbjct: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
NVCYD FPIS IR W LQ+IFV+ PSL+ + H YR EE
Sbjct: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYR----EE----------------- 100
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFM-IGQYLLYGF 181
R+RR ++ Q K N G L TY+ + + ++E F+ + L +GF
Sbjct: 101 ----RERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGF 156
Query: 182 HLEPLFKC-HGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
++ L +C + PCPNI+DC+++RPTEK IF FM + + + L I E+ +L ++ R
Sbjct: 157 NMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216
Query: 241 GL 242
GL
Sbjct: 217 GL 218
>gi|13128960 connexin 31 [Homo sapiens]
Length = 270
Score = 173 bits (439), Expect = 3e-43
Identities = 98/242 (40%), Positives = 137/242 (56%), Gaps = 27/242 (11%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
DW L L V+ +ST G+IWL+++F+FR+LV VAAE VW DEQ F CNT+QPGC
Sbjct: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
NVCYD FPIS IR W LQ+IFV+ PSL+ + H YR EE
Sbjct: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYR----EE----------------- 100
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFM-IGQYLLYGF 181
R+RR ++ Q K N G L TY+ + + ++E F+ + L +GF
Sbjct: 101 ----RERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGF 156
Query: 182 HLEPLFKC-HGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
++ L +C + PCPNI+DC+++RPTEK IF FM + + + L I E+ +L ++ R
Sbjct: 157 NMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216
Query: 241 GL 242
GL
Sbjct: 217 GL 218
>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
Length = 266
Score = 173 bits (438), Expect = 4e-43
Identities = 93/236 (39%), Positives = 140/236 (59%), Gaps = 26/236 (11%)
Query: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
+W L L V+ +ST++ +IWL+++FIFR+LV VAAE+VW+DEQ F+CNT+QPGC
Sbjct: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
Query: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
NVCYD+ FP+S +R W LQ+I V+ PSL+ + H YR EER+R K L+
Sbjct: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR-----EERER-KHHLK------- 108
Query: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181
P + N + RG L TY++ + ++ V+ GF+ + LY +
Sbjct: 109 -HGPNAPSLYD-----------NLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDY 156
Query: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKK 237
+ + C PCP+ +DC++SRPTEK +F FM + A I + LN+ E+F+L K+
Sbjct: 157 DMPRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKR 212
>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
Length = 223
Score = 172 bits (437), Expect = 5e-43
Identities = 99/248 (39%), Positives = 139/248 (56%), Gaps = 34/248 (13%)
Query: 4 WNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRN 63
W L D L V+ +ST G IWL ++F+FR+LV VAAE VW DEQ F CN+ QPGC+N
Sbjct: 3 WMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCKN 62
Query: 64 VCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVEF 123
VC+D FPIS +R W LQ+I VS+PSL+ + H Y E R++
Sbjct: 63 VCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAY-----HEGREK-------------- 103
Query: 124 EMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GFH 182
R R++L ++ + G L Y+I + ++ E+GF++ Y LY GF
Sbjct: 104 ---RHRKKL----------YVSPGTMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFS 150
Query: 183 LEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKRGL 242
+ L KC PCPN +DCF+S+PTEKTIF+LF+ + + + LN +E+ L K +
Sbjct: 151 VPYLIKCDLKPCPNTVDCFISKPTEKTIFILFLVITSCLCIVLNFIELSFLVLKCFIKCC 210
Query: 243 WGKYKLKK 250
KY LKK
Sbjct: 211 LQKY-LKK 217
>gi|145699105 connexin40.1 [Homo sapiens]
Length = 370
Score = 140 bits (354), Expect = 2e-33
Identities = 76/226 (33%), Positives = 122/226 (53%), Gaps = 14/226 (6%)
Query: 5 NLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNV 64
+LLG + ++ + TM+GK+W + + RMLV+ +A V+ DEQ F+CNT QPGC NV
Sbjct: 5 DLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANV 64
Query: 65 CYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVEFE 124
CYD P+S +R+W++Q + V PS V+ + L+R L R R E
Sbjct: 65 CYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPR--------E 116
Query: 125 MPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYGFHLE 184
+RR + +R + P Y+IH+ R+++E F Y L+GF
Sbjct: 117 PASGQRRCPR---PFGERGGLQVP---DFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAP 170
Query: 185 PLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEI 230
F C PC ++DC+VSRPTEK++ +LF+ +++ +S L + ++
Sbjct: 171 KKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADL 216
>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
Length = 279
Score = 132 bits (332), Expect = 8e-31
Identities = 82/247 (33%), Positives = 120/247 (48%), Gaps = 27/247 (10%)
Query: 11 LEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNVCYDQAF 70
L E ST +G++ L +L FR+++L + V+ DEQS F+C+T+QPGC+ C+D
Sbjct: 10 LAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 69
Query: 71 PISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVEFEMPRDRR 130
P+S +R+WV QVI V+ PS +YMG LY V + +
Sbjct: 70 PLSPLRFWVFQVILVAVPSALYMGFTLYH---------------------VIWHWELSGK 108
Query: 131 RLEQELCQLEKRKLNKAPLRGTL--LCTYVIHIFTRSVVEVGFMIGQYLLYGFHLEPLFK 188
E+E + P G+L L YV + R V+E + QY LYGF + F
Sbjct: 109 GKEEETLIQGREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFA 168
Query: 189 CHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKRGLWGKYKL 248
C PC I C +SRP+EKTIFL M ++ L LE+ LG + W +K
Sbjct: 169 CRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGR----WWRTWKH 224
Query: 249 KKEHNEF 255
K +++
Sbjct: 225 KSSSSKY 231
>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
Length = 439
Score = 130 bits (328), Expect = 2e-30
Identities = 54/107 (50%), Positives = 82/107 (76%), Gaps = 1/107 (0%)
Query: 4 WNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRN 63
W+ L LEE+H HST +GK+WLT+L +FR+++ V E +++DEQ+ F CNT QPGC N
Sbjct: 6 WSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDN 65
Query: 64 VCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRL-RVLEEERQR 109
VCYD P+S +R+WV Q++ +S+PS++Y+G+A++RL R E+ER+R
Sbjct: 66 VCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRR 112
Score = 103 bits (256), Expect = 5e-22
Identities = 45/96 (46%), Positives = 63/96 (65%)
Query: 150 RGTLLCTYVIHIFTRSVVEVGFMIGQYLLYGFHLEPLFKCHGHPCPNIIDCFVSRPTEKT 209
R L+ YV + R+ EV F++GQYLLYGF + P F C PCP+++DCFVSRPTEKT
Sbjct: 206 REGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVRPFFPCSRQPCPHVVDCFVSRPTEKT 265
Query: 210 IFLLFMQSIATISLFLNILEIFHLGFKKIKRGLWGK 245
+FLL M ++ + L LN+ E+ HLG + + G+
Sbjct: 266 VFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRGR 301
>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 90.9 bits (224), Expect = 3e-18
Identities = 39/94 (41%), Positives = 62/94 (65%)
Query: 11 LEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNVCYDQAF 70
L E HST +G++ +L FR+++L + V+ DEQS F+C+T+QPGC+ C+D
Sbjct: 29 LAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 88
Query: 71 PISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLE 104
P+S +R+WV QVI V+ PS++YMG+ + V +
Sbjct: 89 PLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQ 122
>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 90.9 bits (224), Expect = 3e-18
Identities = 39/94 (41%), Positives = 62/94 (65%)
Query: 11 LEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNVCYDQAF 70
L E HST +G++ +L FR+++L + V+ DEQS F+C+T+QPGC+ C+D
Sbjct: 29 LAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 88
Query: 71 PISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLE 104
P+S +R+WV QVI V+ PS++YMG+ + V +
Sbjct: 89 PLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQ 122
>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 90.9 bits (224), Expect = 3e-18
Identities = 39/94 (41%), Positives = 62/94 (65%)
Query: 11 LEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNVCYDQAF 70
L E HST +G++ +L FR+++L + V+ DEQS F+C+T+QPGC+ C+D
Sbjct: 29 LAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 88
Query: 71 PISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLE 104
P+S +R+WV QVI V+ PS++YMG+ + V +
Sbjct: 89 PLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQ 122
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,893,146
Number of Sequences: 37866
Number of extensions: 966190
Number of successful extensions: 3914
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 3718
Number of HSP's gapped (non-prelim): 213
length of query: 515
length of database: 18,247,518
effective HSP length: 107
effective length of query: 408
effective length of database: 14,195,856
effective search space: 5791909248
effective search space used: 5791909248
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.