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Search of human proteins with 31377581
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31377581 hypothetical protein LOC124989 [Homo sapiens]
(973 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31377581 hypothetical protein LOC124989 [Homo sapiens] 1906 0.0
gi|4757902 caltractin [Homo sapiens] 50 8e-06
gi|223278387 calmodulin-like 5 [Homo sapiens] 49 2e-05
gi|110227594 calmodulin-like 4 isoform 1 [Homo sapiens] 48 5e-05
gi|58218968 calmodulin 3 [Homo sapiens] 47 9e-05
gi|4502549 calmodulin 2 [Homo sapiens] 47 9e-05
gi|5901912 calmodulin 1 [Homo sapiens] 47 9e-05
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 46 1e-04
gi|4757974 centrin 1 [Homo sapiens] 46 1e-04
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 45 3e-04
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 45 3e-04
gi|71061468 centromere protein E [Homo sapiens] 45 4e-04
gi|46397403 centrin 3 [Homo sapiens] 44 0.001
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 43 0.001
gi|4885111 calmodulin-like 3 [Homo sapiens] 43 0.001
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 43 0.001
gi|4507617 fast skeletal muscle troponin C [Homo sapiens] 43 0.002
gi|50897266 calmodulin-like 6 [Homo sapiens] 42 0.002
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] 40 0.008
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 40 0.011
gi|38570107 CAP-binding protein complex interacting protein 1 is... 40 0.011
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 40 0.014
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 40 0.014
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 40 0.014
gi|4501893 actinin, alpha 2 [Homo sapiens] 39 0.018
gi|4506751 restin isoform a [Homo sapiens] 39 0.024
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 39 0.031
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 39 0.031
gi|113722133 senataxin [Homo sapiens] 38 0.040
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 38 0.040
>gi|31377581 hypothetical protein LOC124989 [Homo sapiens]
Length = 973
Score = 1906 bits (4938), Expect = 0.0
Identities = 973/973 (100%), Positives = 973/973 (100%)
Query: 1 METKVHLFCQAEENIDLLDDGSNSFATDLSSGTINHKKYIKFSKTIEKEISPEIRSLSPE 60
METKVHLFCQAEENIDLLDDGSNSFATDLSSGTINHKKYIKFSKTIEKEISPEIRSLSPE
Sbjct: 1 METKVHLFCQAEENIDLLDDGSNSFATDLSSGTINHKKYIKFSKTIEKEISPEIRSLSPE 60
Query: 61 YKKIFETSIIFCGEEKSSDFSGEKKVGRKSLQVQQHSKRTEIIPPFLKLSKEKVTRKENS 120
YKKIFETSIIFCGEEKSSDFSGEKKVGRKSLQVQQHSKRTEIIPPFLKLSKEKVTRKENS
Sbjct: 61 YKKIFETSIIFCGEEKSSDFSGEKKVGRKSLQVQQHSKRTEIIPPFLKLSKEKVTRKENS 120
Query: 121 LCKLPNQYSVHKTSSPLCTSSAITREKEMLSNLYMTLYDEVTHGYLHSKELSALHKACKI 180
LCKLPNQYSVHKTSSPLCTSSAITREKEMLSNLYMTLYDEVTHGYLHSKELSALHKACKI
Sbjct: 121 LCKLPNQYSVHKTSSPLCTSSAITREKEMLSNLYMTLYDEVTHGYLHSKELSALHKACKI 180
Query: 181 FSKIRSGKIYVNDLPVILCILRISISDLEMRQALKTVDIDAFQDALKIFCRIKGGRVSTD 240
FSKIRSGKIYVNDLPVILCILRISISDLEMRQALKTVDIDAFQDALKIFCRIKGGRVSTD
Sbjct: 181 FSKIRSGKIYVNDLPVILCILRISISDLEMRQALKTVDIDAFQDALKIFCRIKGGRVSTD 240
Query: 241 DVFAVLDSMGIPINREILEEVTKHTYIDSNHMVDIGDIIFTLNELQEQYEDVSITEGSPL 300
DVFAVLDSMGIPINREILEEVTKHTYIDSNHMVDIGDIIFTLNELQEQYEDVSITEGSPL
Sbjct: 241 DVFAVLDSMGIPINREILEEVTKHTYIDSNHMVDIGDIIFTLNELQEQYEDVSITEGSPL 300
Query: 301 NEITSDRKLSSVAGCYLKYKKKNSLSSKLPEPSISKKLNKKSNQYYSKIMENDDLESKRP 360
NEITSDRKLSSVAGCYLKYKKKNSLSSKLPEPSISKKLNKKSNQYYSKIMENDDLESKRP
Sbjct: 301 NEITSDRKLSSVAGCYLKYKKKNSLSSKLPEPSISKKLNKKSNQYYSKIMENDDLESKRP 360
Query: 361 KNTWQIRKFLGGVGSSNVGVQEPYSKNGINFKKHSEKGEIHDSKSKPQSLKSSTSLSKSL 420
KNTWQIRKFLGGVGSSNVGVQEPYSKNGINFKKHSEKGEIHDSKSKPQSLKSSTSLSKSL
Sbjct: 361 KNTWQIRKFLGGVGSSNVGVQEPYSKNGINFKKHSEKGEIHDSKSKPQSLKSSTSLSKSL 420
Query: 421 DKSDISSIPKLQKPAVRKHSSLQKQVSSTEKTAISTLENFCEAISKLQENYIAAEELQSI 480
DKSDISSIPKLQKPAVRKHSSLQKQVSSTEKTAISTLENFCEAISKLQENYIAAEELQSI
Sbjct: 421 DKSDISSIPKLQKPAVRKHSSLQKQVSSTEKTAISTLENFCEAISKLQENYIAAEELQSI 480
Query: 481 LPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPECNALPGVIKAIDKIK 540
LPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPECNALPGVIKAIDKIK
Sbjct: 481 LPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPECNALPGVIKAIDKIK 540
Query: 541 DKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTMMSNTECFSEKL 600
DKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTMMSNTECFSEKL
Sbjct: 541 DKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTMMSNTECFSEKL 600
Query: 601 VLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAK 660
VLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAK
Sbjct: 601 VLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAK 660
Query: 661 VVRNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVS 720
VVRNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVS
Sbjct: 661 VVRNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVS 720
Query: 721 EDNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPD 780
EDNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPD
Sbjct: 721 EDNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPD 780
Query: 781 LEHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDFLMKMKESPHFQKSKATQILLATT 840
LEHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDFLMKMKESPHFQKSKATQILLATT
Sbjct: 781 LEHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDFLMKMKESPHFQKSKATQILLATT 840
Query: 841 QILQNDLVDVSDLKTLLMDKDLHTANAILTVMLRHVPEHESGKVSIQEFMTKLSDILTIP 900
QILQNDLVDVSDLKTLLMDKDLHTANAILTVMLRHVPEHESGKVSIQEFMTKLSDILTIP
Sbjct: 841 QILQNDLVDVSDLKTLLMDKDLHTANAILTVMLRHVPEHESGKVSIQEFMTKLSDILTIP 900
Query: 901 KAAGKFYLICTYCPDLERQAVVYMLKTIQDSIVKAQVSKKQYNMNIKQHKISLHNFCLNS 960
KAAGKFYLICTYCPDLERQAVVYMLKTIQDSIVKAQVSKKQYNMNIKQHKISLHNFCLNS
Sbjct: 901 KAAGKFYLICTYCPDLERQAVVYMLKTIQDSIVKAQVSKKQYNMNIKQHKISLHNFCLNS 960
Query: 961 KANIAKLNPNSKF 973
KANIAKLNPNSKF
Sbjct: 961 KANIAKLNPNSKF 973
>gi|4757902 caltractin [Homo sapiens]
Length = 172
Score = 50.4 bits (119), Expect = 8e-06
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 17/156 (10%)
Query: 672 EELQEVVLAADLLEGD---MIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSEDNMVNIK 728
E+ QE+ A DL + D I K L+ +R +G + KEE++K++ +N
Sbjct: 28 EQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFG 87
Query: 729 DCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPDLEHALKCL 788
D + + TQK S K+ EI +A + + GKI +L+ K L
Sbjct: 88 DFLTVM--TQKMSE-----KDTKE-------EILKAFKLFDDDETGKISFKNLKRVAKEL 133
Query: 789 NVNLTEEDFNEALNCCNVSDNMEVDLKDFLMKMKES 824
NLT+E+ E ++ + + EV ++FL MK++
Sbjct: 134 GENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKT 169
Score = 43.5 bits (101), Expect = 0.001
Identities = 27/120 (22%), Positives = 50/120 (41%)
Query: 544 VDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTMMSNTECFSEKLVLP 603
+D ++L ++ G K E KK+ + T K+NF +F+ M K +
Sbjct: 48 IDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEIL 107
Query: 604 DAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVVR 663
A + DD +S +L L NL +E ++ D +V +EF ++++
Sbjct: 108 KAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMK 167
Score = 37.7 bits (86), Expect = 0.053
Identities = 30/144 (20%), Positives = 65/144 (45%), Gaps = 1/144 (0%)
Query: 598 EKLVLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEE 657
+K + +A + D T+ V +L + +L KK+E + + + K+ F +
Sbjct: 29 QKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGD 88
Query: 658 FAKVV-RNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQS 716
F V+ + M + EE+ + D E I+ KNL+ + +G EE+++++
Sbjct: 89 FLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDE 148
Query: 717 DFVSEDNMVNIKDCMRALRDTQKF 740
D V+ ++ +R ++ T +
Sbjct: 149 ADRDGDGEVSEQEFLRIMKKTSLY 172
>gi|223278387 calmodulin-like 5 [Homo sapiens]
Length = 146
Score = 48.9 bits (115), Expect = 2e-05
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 2/114 (1%)
Query: 472 IAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPECNALPG 531
I A+EL + L +TG NL + + +K++++ + +G + +F+ A K R+ E L
Sbjct: 28 INAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQEFLTAAKKARAGLE--DLQV 85
Query: 532 VIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEF 585
+A D+ D ++ ++L + G L + E + + + +VN++EF
Sbjct: 86 AFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEF 139
Score = 43.9 bits (102), Expect = 7e-04
Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 2/130 (1%)
Query: 605 AIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVVRN 664
A +D T++ +L L + NL + + + V D ++ F+EF +
Sbjct: 16 AFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQEFLTAAKK 75
Query: 665 MRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSEDNM 724
R A LE+LQ A D I L + +G P+EE++ +++ V +D
Sbjct: 76 AR--AGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGR 133
Query: 725 VNIKDCMRAL 734
VN ++ R L
Sbjct: 134 VNYEEFARML 143
Score = 43.5 bits (101), Expect = 0.001
Identities = 29/128 (22%), Positives = 62/128 (48%), Gaps = 3/128 (2%)
Query: 535 AIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTMMSNTE 594
A+D + ++ ++L L+ G LS+ + +K+ ++ +++F+EF+ T
Sbjct: 19 AVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQEFL-TAAKKAR 77
Query: 595 CFSEKLVLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQ 654
E L + A D ++V +L ++ L L ++E A + VD+ +V
Sbjct: 78 AGLEDLQV--AFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVN 135
Query: 655 FEEFAKVV 662
+EEFA+++
Sbjct: 136 YEEFARML 143
Score = 32.3 bits (72), Expect = 2.2
Identities = 27/135 (20%), Positives = 56/135 (41%), Gaps = 2/135 (1%)
Query: 760 EIKEAANILSHVDNGKIGIPDLEHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDFLM 819
+ K+A + + NG I +L ALK NL+E + ++ + + E+ ++FL
Sbjct: 12 QYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQEFLT 71
Query: 820 KMKESPHFQKSKATQILLATTQILQNDLVDVSDLKTLLMDKDLHTANAILTVMLRHVPEH 879
K++ + Q+ + + V +L+ + L M+R
Sbjct: 72 AAKKAR--AGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVD 129
Query: 880 ESGKVSIQEFMTKLS 894
+ G+V+ +EF L+
Sbjct: 130 QDGRVNYEEFARMLA 144
>gi|110227594 calmodulin-like 4 isoform 1 [Homo sapiens]
Length = 196
Score = 47.8 bits (112), Expect = 5e-05
Identities = 39/147 (26%), Positives = 62/147 (42%), Gaps = 3/147 (2%)
Query: 750 ASNLKLPKVNEIKEAANILSHVDNGKIGIPDLEHALKCLNVNLTEEDFNEALNCCNVSDN 809
A L ++NE KE ++ GKI DL A++CL + T + L + N
Sbjct: 45 AKFLSQDQINEYKECFSLYDKQQRGKIKATDLMVAMRCLGASPTPGEVQRHLQTHGIDGN 104
Query: 810 MEVDLKDFLMKMKESPHFQKSKATQILLATTQI--LQNDLVDVSDLKTLLMDKDLHTANA 867
E+D FL M Q+ +ILLA + + V SDL++ L +
Sbjct: 105 GELDFSTFLTIMHMQIK-QEDPKKEILLAMLMVDKEKKGYVMASDLRSKLTSLGEKLTHK 163
Query: 868 ILTVMLRHVPEHESGKVSIQEFMTKLS 894
+ + R +GKV EF+ K++
Sbjct: 164 EVDDLFREADIEPNGKVKYDEFIHKIT 190
Score = 33.5 bits (75), Expect = 0.99
Identities = 15/54 (27%), Positives = 29/54 (53%)
Query: 464 ISKLQENYIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNAL 517
+ K ++ Y+ A +L+S L S G L +E + + NG V+ D+F++ +
Sbjct: 136 VDKEKKGYVMASDLRSKLTSLGEKLTHKEVDDLFREADIEPNGKVKYDEFIHKI 189
Score = 32.0 bits (71), Expect = 2.9
Identities = 30/142 (21%), Positives = 56/142 (39%)
Query: 517 LAKERSFPECNALPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGE 576
+AK S + N DK + + DL ++ G + E ++ +
Sbjct: 44 MAKFLSQDQINEYKECFSLYDKQQRGKIKATDLMVAMRCLGASPTPGEVQRHLQTHGIDG 103
Query: 577 TKKVNFKEFIDTMMSNTECFSEKLVLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKD 636
+++F F+ M + K + A+ +D +K V SDL + L+SL L
Sbjct: 104 NGELDFSTFLTIMHMQIKQEDPKKEILLAMLMVDKEKKGYVMASDLRSKLTSLGEKLTHK 163
Query: 637 EFLAALELVTVDEGDKVQFEEF 658
E ++ KV+++EF
Sbjct: 164 EVDDLFREADIEPNGKVKYDEF 185
>gi|58218968 calmodulin 3 [Homo sapiens]
Length = 149
Score = 47.0 bits (110), Expect = 9e-05
Identities = 31/132 (23%), Positives = 58/132 (43%), Gaps = 1/132 (0%)
Query: 604 DAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVV- 662
+A D T++ +L + SL N + E + V D + F EF ++
Sbjct: 15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 74
Query: 663 RNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSED 722
R M+D EE++E D I+ L + N+G K EEV+++++ + D
Sbjct: 75 RKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGD 134
Query: 723 NMVNIKDCMRAL 734
VN ++ ++ +
Sbjct: 135 GQVNYEEFVQMM 146
Score = 43.5 bits (101), Expect = 0.001
Identities = 29/137 (21%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Query: 457 LENFCEAIS---KLQENYIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDF 513
+ F EA S K + I +EL +++ S G N + E Q ++ + + NG ++ +F
Sbjct: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69
Query: 514 VNALAKERSFPECNA-LPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELT 572
+ +A++ + + + DK + + +L + N G L+ E ++
Sbjct: 70 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREA 129
Query: 573 EAGETKKVNFKEFIDTM 589
+ +VN++EF+ M
Sbjct: 130 DIDGDGQVNYEEFVQMM 146
Score = 38.5 bits (88), Expect = 0.031
Identities = 31/160 (19%), Positives = 66/160 (41%), Gaps = 17/160 (10%)
Query: 665 MRDAARLEELQEVVLAADLLEGD---MIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSE 721
M D E++ E A L + D I K L +R++G + E++ ++
Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60
Query: 722 DNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPDL 781
+ ++ + + + K ++ EI+EA + NG I +L
Sbjct: 61 NGTIDFPEFLTMMARKMKDTD--------------SEEEIREAFRVFDKDGNGYISAAEL 106
Query: 782 EHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDFLMKM 821
H + L LT+E+ +E + ++ + +V+ ++F+ M
Sbjct: 107 RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146
Score = 30.8 bits (68), Expect = 6.4
Identities = 23/139 (16%), Positives = 58/139 (41%), Gaps = 25/139 (17%)
Query: 166 LHSKELSALHKACKIFSKIRSGKIYVNDLPVILCILRISISDLEMRQALKTVDIDA---- 221
L ++++ +A +F K G I +L ++ L + ++ E++ + VD D
Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64
Query: 222 ---------------------FQDALKIFCRIKGGRVSTDDVFAVLDSMGIPINREILEE 260
++A ++F + G +S ++ V+ ++G + E ++E
Sbjct: 65 DFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE 124
Query: 261 VTKHTYIDSNHMVDIGDII 279
+ + ID + V+ + +
Sbjct: 125 MIREADIDGDGQVNYEEFV 143
>gi|4502549 calmodulin 2 [Homo sapiens]
Length = 149
Score = 47.0 bits (110), Expect = 9e-05
Identities = 31/132 (23%), Positives = 58/132 (43%), Gaps = 1/132 (0%)
Query: 604 DAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVV- 662
+A D T++ +L + SL N + E + V D + F EF ++
Sbjct: 15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 74
Query: 663 RNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSED 722
R M+D EE++E D I+ L + N+G K EEV+++++ + D
Sbjct: 75 RKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGD 134
Query: 723 NMVNIKDCMRAL 734
VN ++ ++ +
Sbjct: 135 GQVNYEEFVQMM 146
Score = 43.5 bits (101), Expect = 0.001
Identities = 29/137 (21%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Query: 457 LENFCEAIS---KLQENYIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDF 513
+ F EA S K + I +EL +++ S G N + E Q ++ + + NG ++ +F
Sbjct: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69
Query: 514 VNALAKERSFPECNA-LPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELT 572
+ +A++ + + + DK + + +L + N G L+ E ++
Sbjct: 70 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREA 129
Query: 573 EAGETKKVNFKEFIDTM 589
+ +VN++EF+ M
Sbjct: 130 DIDGDGQVNYEEFVQMM 146
Score = 38.5 bits (88), Expect = 0.031
Identities = 31/160 (19%), Positives = 66/160 (41%), Gaps = 17/160 (10%)
Query: 665 MRDAARLEELQEVVLAADLLEGD---MIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSE 721
M D E++ E A L + D I K L +R++G + E++ ++
Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60
Query: 722 DNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPDL 781
+ ++ + + + K ++ EI+EA + NG I +L
Sbjct: 61 NGTIDFPEFLTMMARKMKDTD--------------SEEEIREAFRVFDKDGNGYISAAEL 106
Query: 782 EHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDFLMKM 821
H + L LT+E+ +E + ++ + +V+ ++F+ M
Sbjct: 107 RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146
Score = 30.8 bits (68), Expect = 6.4
Identities = 23/139 (16%), Positives = 58/139 (41%), Gaps = 25/139 (17%)
Query: 166 LHSKELSALHKACKIFSKIRSGKIYVNDLPVILCILRISISDLEMRQALKTVDIDA---- 221
L ++++ +A +F K G I +L ++ L + ++ E++ + VD D
Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64
Query: 222 ---------------------FQDALKIFCRIKGGRVSTDDVFAVLDSMGIPINREILEE 260
++A ++F + G +S ++ V+ ++G + E ++E
Sbjct: 65 DFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE 124
Query: 261 VTKHTYIDSNHMVDIGDII 279
+ + ID + V+ + +
Sbjct: 125 MIREADIDGDGQVNYEEFV 143
>gi|5901912 calmodulin 1 [Homo sapiens]
Length = 149
Score = 47.0 bits (110), Expect = 9e-05
Identities = 31/132 (23%), Positives = 58/132 (43%), Gaps = 1/132 (0%)
Query: 604 DAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVV- 662
+A D T++ +L + SL N + E + V D + F EF ++
Sbjct: 15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 74
Query: 663 RNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSED 722
R M+D EE++E D I+ L + N+G K EEV+++++ + D
Sbjct: 75 RKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGD 134
Query: 723 NMVNIKDCMRAL 734
VN ++ ++ +
Sbjct: 135 GQVNYEEFVQMM 146
Score = 43.5 bits (101), Expect = 0.001
Identities = 29/137 (21%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Query: 457 LENFCEAIS---KLQENYIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDF 513
+ F EA S K + I +EL +++ S G N + E Q ++ + + NG ++ +F
Sbjct: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69
Query: 514 VNALAKERSFPECNA-LPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELT 572
+ +A++ + + + DK + + +L + N G L+ E ++
Sbjct: 70 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREA 129
Query: 573 EAGETKKVNFKEFIDTM 589
+ +VN++EF+ M
Sbjct: 130 DIDGDGQVNYEEFVQMM 146
Score = 38.5 bits (88), Expect = 0.031
Identities = 31/160 (19%), Positives = 66/160 (41%), Gaps = 17/160 (10%)
Query: 665 MRDAARLEELQEVVLAADLLEGD---MIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSE 721
M D E++ E A L + D I K L +R++G + E++ ++
Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60
Query: 722 DNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPDL 781
+ ++ + + + K ++ EI+EA + NG I +L
Sbjct: 61 NGTIDFPEFLTMMARKMKDTD--------------SEEEIREAFRVFDKDGNGYISAAEL 106
Query: 782 EHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDFLMKM 821
H + L LT+E+ +E + ++ + +V+ ++F+ M
Sbjct: 107 RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146
Score = 30.8 bits (68), Expect = 6.4
Identities = 23/139 (16%), Positives = 58/139 (41%), Gaps = 25/139 (17%)
Query: 166 LHSKELSALHKACKIFSKIRSGKIYVNDLPVILCILRISISDLEMRQALKTVDIDA---- 221
L ++++ +A +F K G I +L ++ L + ++ E++ + VD D
Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64
Query: 222 ---------------------FQDALKIFCRIKGGRVSTDDVFAVLDSMGIPINREILEE 260
++A ++F + G +S ++ V+ ++G + E ++E
Sbjct: 65 DFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE 124
Query: 261 VTKHTYIDSNHMVDIGDII 279
+ + ID + V+ + +
Sbjct: 125 MIREADIDGDGQVNYEEFV 143
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/144 (21%), Positives = 67/144 (46%), Gaps = 5/144 (3%)
Query: 458 ENFCEAISKLQENYIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNAL 517
E +A+ + + + ELQ L + GI L + +KI T N++G ++ ++F+ L
Sbjct: 25 ETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYL 84
Query: 518 AKERSFPECNALPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGET 577
+ K++DK D ++ ++ LQ G+ +S+ + + I + + T
Sbjct: 85 KDHE-----KKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGT 139
Query: 578 KKVNFKEFIDTMMSNTECFSEKLV 601
V++ E+ D + N E+++
Sbjct: 140 MTVDWNEWRDYFLFNPVTDIEEII 163
Score = 41.6 bits (96), Expect = 0.004
Identities = 33/152 (21%), Positives = 69/152 (45%), Gaps = 20/152 (13%)
Query: 666 RDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSEDNMV 725
+DA + + + A D ++ L++ LRN+GI ++ EKI + V++D +
Sbjct: 16 QDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKL 75
Query: 726 NIKDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPDLEHAL 785
+ ++ M+ L+D +K ++K A L ++GKI ++ +L
Sbjct: 76 DFEEFMKYLKDHEK--------------------KMKLAFKSLDKNNDGKIEASEIVQSL 115
Query: 786 KCLNVNLTEEDFNEALNCCNVSDNMEVDLKDF 817
+ L + ++E+ L +V M VD ++
Sbjct: 116 QTLGLTISEQQAELILQSIDVDGTMTVDWNEW 147
Score = 41.2 bits (95), Expect = 0.005
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 6/149 (4%)
Query: 510 LDDFVNALAKERSFPECNALPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKIT 569
L DFV A + + + +A+D+ D VD +L L+N GI L + +KI
Sbjct: 5 LRDFVLPTAACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIF 64
Query: 570 ELTEAGETKKVNFKEFIDTMMSNTECFSEKLVLPDAIETLDDLRKETVSVSDLWNTLSSL 629
+ + K++F+EF+ + + +K+ L A ++LD + S++ +L +L
Sbjct: 65 TTGDVNKDGKLDFEEFMKYLKDH----EKKMKL--AFKSLDKNNDGKIEASEIVQSLQTL 118
Query: 630 NSNLKKDEFLAALELVTVDEGDKVQFEEF 658
+ + + L+ + VD V + E+
Sbjct: 119 GLTISEQQAELILQSIDVDGTMTVDWNEW 147
>gi|4757974 centrin 1 [Homo sapiens]
Length = 172
Score = 46.2 bits (108), Expect = 1e-04
Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 17/156 (10%)
Query: 672 EELQEVVLAADLLEGD---MIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSEDNMVNIK 728
++ QEV A DL + D I K L+ +R +G + KEE++K++ ++
Sbjct: 28 DQKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFN 87
Query: 729 DCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPDLEHALKCL 788
D + + TQK S K+ EI +A + + GKI +L+ L
Sbjct: 88 DFLAVM--TQKMSE-----KDTKE-------EILKAFRLFDDDETGKISFKNLKRVANEL 133
Query: 789 NVNLTEEDFNEALNCCNVSDNMEVDLKDFLMKMKES 824
NLT+E+ E ++ + + EV+ ++FL MK++
Sbjct: 134 GENLTDEELQEMIDEADRDGDGEVNEEEFLRIMKKT 169
Score = 37.4 bits (85), Expect = 0.069
Identities = 30/144 (20%), Positives = 63/144 (43%), Gaps = 1/144 (0%)
Query: 598 EKLVLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEE 657
+K + +A + D T+ +L + +L +K+E + V + K+ F +
Sbjct: 29 QKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFND 88
Query: 658 FAKVV-RNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQS 716
F V+ + M + EE+ + D E I+ KNL+ +G EE+++++
Sbjct: 89 FLAVMTQKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEMIDE 148
Query: 717 DFVSEDNMVNIKDCMRALRDTQKF 740
D VN ++ +R ++ T +
Sbjct: 149 ADRDGDGEVNEEEFLRIMKKTSLY 172
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 45.4 bits (106), Expect = 3e-04
Identities = 27/116 (23%), Positives = 59/116 (50%), Gaps = 5/116 (4%)
Query: 472 IAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPECNALPG 531
+ +L L G++ + E QKIV ++ +G ++ ++FV+ L L
Sbjct: 65 LCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHE-----KKLRL 119
Query: 532 VIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFID 587
V K++DK D +D +++ L++ G+ +S+ + +KI + + T +++ E+ D
Sbjct: 120 VFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRD 175
Score = 36.2 bits (82), Expect = 0.15
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Query: 607 ETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVVRNMR 666
+TLD R + V+DL L L + + E ++ D ++ FEEF +++
Sbjct: 55 QTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHE 114
Query: 667 DAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQS 716
RL V + D I + + LR++G+K +++ EKIL+S
Sbjct: 115 KKLRL-----VFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKS 159
Score = 31.2 bits (69), Expect = 4.9
Identities = 21/120 (17%), Positives = 54/120 (45%), Gaps = 20/120 (16%)
Query: 698 LRNVGIKSPKEEVEKILQSDFVSEDNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPK 757
LR +G+ + E++KI+Q+ D ++ ++ + L+D +K
Sbjct: 74 LRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEK------------------ 115
Query: 758 VNEIKEAANILSHVDNGKIGIPDLEHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDF 817
+++ L ++G+I ++ +L+ L V ++E+ + L + + M +D ++
Sbjct: 116 --KLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEW 173
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 45.4 bits (106), Expect = 3e-04
Identities = 27/116 (23%), Positives = 59/116 (50%), Gaps = 5/116 (4%)
Query: 472 IAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPECNALPG 531
+ +L L G++ + E QKIV ++ +G ++ ++FV+ L L
Sbjct: 65 LCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHE-----KKLRL 119
Query: 532 VIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFID 587
V K++DK D +D +++ L++ G+ +S+ + +KI + + T +++ E+ D
Sbjct: 120 VFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRD 175
Score = 36.2 bits (82), Expect = 0.15
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Query: 607 ETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVVRNMR 666
+TLD R + V+DL L L + + E ++ D ++ FEEF +++
Sbjct: 55 QTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHE 114
Query: 667 DAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQS 716
RL V + D I + + LR++G+K +++ EKIL+S
Sbjct: 115 KKLRL-----VFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKS 159
Score = 31.2 bits (69), Expect = 4.9
Identities = 21/120 (17%), Positives = 54/120 (45%), Gaps = 20/120 (16%)
Query: 698 LRNVGIKSPKEEVEKILQSDFVSEDNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPK 757
LR +G+ + E++KI+Q+ D ++ ++ + L+D +K
Sbjct: 74 LRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEK------------------ 115
Query: 758 VNEIKEAANILSHVDNGKIGIPDLEHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDF 817
+++ L ++G+I ++ +L+ L V ++E+ + L + + M +D ++
Sbjct: 116 --KLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEW 173
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 44.7 bits (104), Expect = 4e-04
Identities = 173/869 (19%), Positives = 353/869 (40%), Gaps = 123/869 (14%)
Query: 83 EKKVGRKSLQVQQHSKRTEIIPPFLKLSKEKVTRKENSLCKLPNQ------------YSV 130
E+K+ KS Q+Q+ ++ + + ++K+ EN +L N+
Sbjct: 1126 EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELA 1185
Query: 131 HKTSSPLCTSSAITREKEMLSNLYMTLYDEVTH--GYLHSKELSALHKACKIFSKIRSGK 188
K + +IT+E+++L L + E H GY+ E + L +++
Sbjct: 1186 QKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTK----EELKIAH 1241
Query: 189 IYVNDLPVILCILRISISDLEMRQALKTVDID----AFQDALKIFCRIKGGRVSTDDVFA 244
I++ + + LR S+S+ + Q + T D++ Q+ + + + + +V
Sbjct: 1242 IHLKEHQETIDELRRSVSE-KTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSE 1300
Query: 245 VLDSMGIPINREILEEVTKHTYIDSNHMVDIGDIIFTLNE-LQEQYEDV-SITEGSPLNE 302
++M E+L E + T DS + I LNE QE E++ S+T+ +
Sbjct: 1301 TQETMN---ELELLTE--QSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTK--ERDN 1353
Query: 303 ITSDRKLSSVAGCYLKYKKKNSLSSKLPEPSISKKLN---KKSNQYYSKIMENDDLESKR 359
+ + ++ V LK + +L +K+ E ++ + K+ + +KI+ ++E +
Sbjct: 1354 LKTIKEALEVKHDQLKEHIRETL-AKIQESQSKQEQSLNMKEKDNETTKIV--SEMEQFK 1410
Query: 360 PKNTWQIRKFLGGVGSSNVGVQEPYSKNGINFKKHSEKGEIHDSKSKPQSLKSSTSLSKS 419
PK++ +R + +G S +QE + + S E D + + L+S + K
Sbjct: 1411 PKDSALLRIEIEMLGLSK-RLQESHD------EMKSVAKEKDDLQRLQEVLQSESDQLKE 1463
Query: 420 LDKSDISSIPKLQKPAVRKHSSLQKQVS---------STEKTAISTLENFCEAI-----S 465
K ++ + ++ H L++Q S ++T IST++ EAI +
Sbjct: 1464 NIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQN 1523
Query: 466 KLQENYIAAEEL---QSILPSTGINLL----------DEEFQKIVTDTSRNENGMVELDD 512
K+QE Y E+ Q +N L D Q I + N + E +
Sbjct: 1524 KIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQE 1583
Query: 513 FVNALAKERSFPECNALPGVIK-AIDKIKDKNVD--------YEDLNTCLQNFGIYLSKP 563
+ + KE+ E + ++ D++K+ + E L+ + ++
Sbjct: 1584 EIQIMIKEKE--EMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQE 1641
Query: 564 EFKKITELTEAGETKKVNFKEFIDTMMSNTECFSEKL-VLPDAIETLDDLR--KETVSVS 620
+ +I L E ET+K+N + + T+ E L + + DDLR +ET+ V
Sbjct: 1642 KMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVE 1701
Query: 621 D---LWNTLSSLNSNLKKDEFLAALEL------VTVDEGDKVQFEEFAKVVRNMRDAARL 671
N ++ +L+K E L + + T+D+ + E+ ++ +D L
Sbjct: 1702 RDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKD---L 1758
Query: 672 EELQEVVLAADLLEGDMIAGKNLEDFLR--NVGIKSPKEEVEKILQSDFVSEDNMVNIKD 729
E + + A DL +++ LR ++ +K +E ++K+ D + N++
Sbjct: 1759 EHSNDALKAQDL---------KIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQK 1809
Query: 730 CMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPDLEHALKCL- 788
+ K I K + + ++ E +S ++ K I D L L
Sbjct: 1810 DLE--NSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLE 1867
Query: 789 --NVNLTE---EDFNEALNCCNVSDNM---EVDLKDFLMKMKESPHFQKSKATQIL--LA 838
N+NL + E+ E + DN+ E LK ++KES K++ +I L
Sbjct: 1868 IENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELK 1927
Query: 839 TTQILQNDLVDVSD-LKTLLMDKDLHTAN 866
T ++L + + D L+ + +K + ++
Sbjct: 1928 TARMLSKEHKETVDKLREKISEKTIQISD 1956
Score = 33.9 bits (76), Expect = 0.76
Identities = 53/234 (22%), Positives = 105/234 (44%), Gaps = 31/234 (13%)
Query: 532 VIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFI-DTMM 590
V + DK+ + D E+ N LQ +KI EL +A E + + K+ + +T
Sbjct: 1797 VSEKTDKLSNMQKDLENSNAKLQ-----------EKIQEL-KANEHQLITLKKDVNETQK 1844
Query: 591 SNTECFSEKLVLPDAIETLDDLRKETVSVSD-LWNTLSSLNSNLKKDEFLAALELVTVDE 649
+E K + D TL L E ++++ L L + S +K+ + L V+E
Sbjct: 1845 KVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERD-----NLRRVEE 1899
Query: 650 GDKVQFEEFAKVVRNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEE 709
K++ ++ + ++ + AR E+Q+ + A +L + K D LR ++
Sbjct: 1900 TLKLERDQLKESLQETK--ARDLEIQQELKTARMLSKE---HKETVDKLR-------EKI 1947
Query: 710 VEKILQSDFVSEDNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKE 763
EK +Q + +D + + + +++ QK + KE N+ K+NE+++
Sbjct: 1948 SEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQ 2001
>gi|46397403 centrin 3 [Homo sapiens]
Length = 167
Score = 43.5 bits (101), Expect = 0.001
Identities = 30/144 (20%), Positives = 60/144 (41%)
Query: 519 KERSFPECNALPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETK 578
+E S + + + D KD+ +DY +L ++ G + K + KI + + T
Sbjct: 20 RELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATG 79
Query: 579 KVNFKEFIDTMMSNTECFSEKLVLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEF 638
K+ F++F + + + A + DD +S+ +L L N+ +E
Sbjct: 80 KITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEEL 139
Query: 639 LAALELVTVDEGDKVQFEEFAKVV 662
A +E D ++ EEF ++
Sbjct: 140 RAMIEEFDKDGDGEINQEEFIAIM 163
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/112 (23%), Positives = 57/112 (50%), Gaps = 5/112 (4%)
Query: 476 ELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPECNALPGVIKA 535
+L +PS + + QKIV ++ +G ++ ++FV+ L L V K+
Sbjct: 35 KLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHE-----KKLRLVFKS 89
Query: 536 IDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFID 587
+DK D +D +++ L++ G+ +S+ + +KI + + T +++ E+ D
Sbjct: 90 LDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRD 141
Score = 31.2 bits (69), Expect = 4.9
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 18/103 (17%)
Query: 627 SSLNSNLKKDEFLAALELVT--------VDEGDK-----VQFEEFAKVVRNMRDAARLEE 673
+ L S K F+ + E T V GDK + FEEF +++ RL
Sbjct: 28 AELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRL-- 85
Query: 674 LQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQS 716
V + D I + + LR++G+K +++ EKIL+S
Sbjct: 86 ---VFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKS 125
>gi|4885111 calmodulin-like 3 [Homo sapiens]
Length = 149
Score = 43.1 bits (100), Expect = 0.001
Identities = 31/136 (22%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Query: 460 FCEAIS---KLQENYIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNA 516
F EA S K + I EL +++ S G N + E + ++++ R+ NG V+ +F+
Sbjct: 13 FKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFLGM 72
Query: 517 LAKE-RSFPECNALPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAG 575
+A++ + + + DK + V +L + G LS E ++ +
Sbjct: 73 MARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTD 132
Query: 576 ETKKVNFKEFIDTMMS 591
+VN++EF+ ++S
Sbjct: 133 GDGQVNYEEFVRVLVS 148
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/119 (23%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
Query: 617 VSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEF-AKVVRNMRDAARLEELQ 675
++ +L + SL N + E + + D V F EF + R M+D EE++
Sbjct: 28 ITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFLGMMARKMKDTDNEEEIR 87
Query: 676 EVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSEDNMVNIKDCMRAL 734
E D ++ L + +G K EEV++++++ D VN ++ +R L
Sbjct: 88 EAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVL 146
Score = 38.5 bits (88), Expect = 0.031
Identities = 26/126 (20%), Positives = 53/126 (42%)
Query: 537 DKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTMMSNTECF 596
DK D + +L T +++ G ++ E + + + V+F EF+ M +
Sbjct: 21 DKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFLGMMARKMKDT 80
Query: 597 SEKLVLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFE 656
+ + +A D VS ++L + ++ L L +E + D +V +E
Sbjct: 81 DNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYE 140
Query: 657 EFAKVV 662
EF +V+
Sbjct: 141 EFVRVL 146
Score = 33.1 bits (74), Expect = 1.3
Identities = 14/59 (23%), Positives = 31/59 (52%)
Query: 760 EIKEAANILSHVDNGKIGIPDLEHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDFL 818
EI+EA + NG + +L H + L L++E+ +E + + + +V+ ++F+
Sbjct: 85 EIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFV 143
Score = 31.6 bits (70), Expect = 3.8
Identities = 13/50 (26%), Positives = 27/50 (54%)
Query: 471 YIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALAKE 520
+++A EL+ ++ G L DEE +++ + +G V ++FV L +
Sbjct: 100 FVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLVSK 149
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/112 (23%), Positives = 57/112 (50%), Gaps = 5/112 (4%)
Query: 476 ELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPECNALPGVIKA 535
+L +PS + + QKIV ++ +G ++ ++FV+ L L V K+
Sbjct: 35 KLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHE-----KKLRLVFKS 89
Query: 536 IDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFID 587
+DK D +D +++ L++ G+ +S+ + +KI + + T +++ E+ D
Sbjct: 90 LDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRD 141
Score = 31.2 bits (69), Expect = 4.9
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 18/103 (17%)
Query: 627 SSLNSNLKKDEFLAALELVT--------VDEGDK-----VQFEEFAKVVRNMRDAARLEE 673
+ L S K F+ + E T V GDK + FEEF +++ RL
Sbjct: 28 AELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRL-- 85
Query: 674 LQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQS 716
V + D I + + LR++G+K +++ EKIL+S
Sbjct: 86 ---VFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKS 125
>gi|4507617 fast skeletal muscle troponin C [Homo sapiens]
Length = 160
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 4/126 (3%)
Query: 617 VSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEF-AKVVRNMRDAAR---LE 672
+SV +L + L K+E A +E V D + FEEF +VR M++ A+ E
Sbjct: 35 ISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEE 94
Query: 673 ELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSEDNMVNIKDCMR 732
EL E D I + L + R G EE+E +++ + D ++ + ++
Sbjct: 95 ELAECFRIFDRNADGYIDPEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLK 154
Query: 733 ALRDTQ 738
+ Q
Sbjct: 155 MMEGVQ 160
Score = 39.3 bits (90), Expect = 0.018
Identities = 15/49 (30%), Positives = 30/49 (61%)
Query: 469 ENYIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNAL 517
+ YI EEL I ++G ++ DEE + ++ D +N +G ++ D+F+ +
Sbjct: 108 DGYIDPEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMM 156
Score = 35.8 bits (81), Expect = 0.20
Identities = 22/122 (18%), Positives = 54/122 (44%), Gaps = 4/122 (3%)
Query: 472 IAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDF----VNALAKERSFPECN 527
I+ +EL +++ G EE I+ + + +G ++ ++F V + ++
Sbjct: 35 ISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEE 94
Query: 528 ALPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFID 587
L + D+ D +D E+L + G +++ E + + + + +++F EF+
Sbjct: 95 ELAECFRIFDRNADGYIDPEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLK 154
Query: 588 TM 589
M
Sbjct: 155 MM 156
Score = 35.0 bits (79), Expect = 0.34
Identities = 25/150 (16%), Positives = 63/150 (42%), Gaps = 4/150 (2%)
Query: 751 SNLKLPKVNEIKEAANILSHVDNGKIGIPDLEHALKCLNVNLTEEDFNEALNCCNVSDNM 810
S L + E K A ++ G I + +L ++ L T+E+ + + + +
Sbjct: 10 SYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSG 69
Query: 811 EVDLKDFL-MKMKESPHFQKSKATQILLATTQILQND---LVDVSDLKTLLMDKDLHTAN 866
+D ++FL M +++ K K+ + L +I + +D +L + H +
Sbjct: 70 TIDFEEFLVMMVRQMKEDAKGKSEEELAECFRIFDRNADGYIDPEELAEIFRASGEHVTD 129
Query: 867 AILTVMLRHVPEHESGKVSIQEFMTKLSDI 896
+ +++ ++ G++ EF+ + +
Sbjct: 130 EEIESLMKDGDKNNDGRIDFDEFLKMMEGV 159
Score = 32.0 bits (71), Expect = 2.9
Identities = 34/154 (22%), Positives = 65/154 (42%), Gaps = 14/154 (9%)
Query: 672 EELQEVVLAADLLEGDM---IAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSEDNMVNIK 728
E + E A D+ + D I+ K L +R +G KEE++ I++ V ED I
Sbjct: 15 EMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEE--VDEDGSGTI- 71
Query: 729 DCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPDLEHALKCL 788
D ++F + R+ + K E+ E I +G I +L +
Sbjct: 72 -------DFEEFLVMM-VRQMKEDAKGKSEEELAECFRIFDRNADGYIDPEELAEIFRAS 123
Query: 789 NVNLTEEDFNEALNCCNVSDNMEVDLKDFLMKMK 822
++T+E+ + + +++ +D +FL M+
Sbjct: 124 GEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMME 157
>gi|50897266 calmodulin-like 6 [Homo sapiens]
Length = 181
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/173 (20%), Positives = 70/173 (40%), Gaps = 9/173 (5%)
Query: 422 KSDISSIPKLQKPAVRKHSSLQKQVSSTEKTAISTLENFCEAISKLQEN---YIAAEELQ 478
+ +IS P PA S Q TE+ + ++ + E + EL+
Sbjct: 4 QQEISLQPWCHHPA----ESCQTTTDMTERLSAEQIKEYKGVFEMFDEEGNGEVKTGELE 59
Query: 479 SILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALA--KERSFPECNALPGVIKAI 536
++ GIN E + D R+ G D F+ + E++ + + L +
Sbjct: 60 WLMSLLGINPTKSELASMAKDVDRDNKGFFNCDGFLALMGVYHEKAQNQESELRAAFRVF 119
Query: 537 DKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTM 589
DK +D+ L L N G L++ E +++ + + + ++++EF+ M
Sbjct: 120 DKEGKGYIDWNTLKYVLMNAGEPLNEVEAEQMMKEADKDGDRTIDYEEFVAMM 172
>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
Length = 887
Score = 40.4 bits (93), Expect = 0.008
Identities = 44/203 (21%), Positives = 88/203 (43%), Gaps = 17/203 (8%)
Query: 426 SSIPKLQKPAVRKHSSLQKQVSSTEKTAISTLENFCEAISKLQENYIAAEELQSILPSTG 485
+ + ++ + ++ H +L+ Q+S + S + N+ I +L+ ++ +E I +
Sbjct: 648 TKMEEIGRISIEMHGTLEDQLSHLRQYEKSIV-NYKPKIDQLEGDHQLIQEAL-IFDNKH 705
Query: 486 INLLDEE----FQKIVTDTSRNENGMVELDDFVNALAKERSFPECNALPGVIKAIDKIKD 541
N E +++++T +R N + + + AK S + N D+ K
Sbjct: 706 TNYTMEHIRVGWEQLLTTIARTINEVE--NQILTRDAKGISQEQMNEFRASFNHFDRKKT 763
Query: 542 KNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTMMSNTE------- 594
+D +D CL + G + + EF +I + + V F+ FID M T
Sbjct: 764 GMMDTDDFRACLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQ 823
Query: 595 -CFSEKLVLPDA-IETLDDLRKE 615
S K++ D T+D+LR+E
Sbjct: 824 VMASFKILAGDKNYITMDELRRE 846
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 40.0 bits (92), Expect = 0.011
Identities = 69/319 (21%), Positives = 129/319 (40%), Gaps = 50/319 (15%)
Query: 611 DLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVVRNMRDAAR 670
DL+ S+ DL N L+ LKK +F +L + E ++ +F K ++ ++ AR
Sbjct: 1059 DLKLAQESILDLENDKQQLDERLKKKDF-EYCQLQSKVEDEQTLGLQFQKKIKELQ--AR 1115
Query: 671 LEELQEVVLAADLLEGDMIAGKNLEDFLRNV-----------GIKSPKEEVEKILQSDFV 719
+EEL+E + A K D+ R + G+ S + E+ K +++F+
Sbjct: 1116 IEELEEEIEAERATRAK--TEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFL 1173
Query: 720 S-----EDNMVNIKDCMRALR-----DTQKFSNYID--------FRKEASNLKLPKVNEI 761
E+ + + + ALR + ID KE S KL EI
Sbjct: 1174 KLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL----EI 1229
Query: 762 KEAANILSHVDNGKIGIPDLEHALKCLNVNLTE-----EDFNEALN-CCNVSDNMEVDLK 815
+ ++ + V K +LE + L L+E E+ +L+ ++ +
Sbjct: 1230 DDLSSSMESVSKSK---ANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAG 1286
Query: 816 DFLMKM--KESPHFQKSKATQILLATTQILQNDLVDVSDLKTLLMDKDLHTANAILTVML 873
+ ++ KES Q S++ Q T+ L+ L + + K L L ++ ++
Sbjct: 1287 ELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHA-LQSSRHDCDLLR 1345
Query: 874 RHVPEHESGKVSIQEFMTK 892
E + GK +Q ++K
Sbjct: 1346 EQYEEEQEGKAELQRALSK 1364
>gi|38570107 CAP-binding protein complex interacting protein 1
isoform a [Homo sapiens]
Length = 1501
Score = 40.0 bits (92), Expect = 0.011
Identities = 84/508 (16%), Positives = 188/508 (37%), Gaps = 105/508 (20%)
Query: 383 PYSKNGINFKKHSEKGEIHDSKSKPQSLKSSTSLS---KSLDKSDISSIPKLQKPAVRKH 439
P+++ + + HS ++ P +SS++ + +L D+ I L + +
Sbjct: 15 PHTRKFTHSRPHSSPCRVYSRNGSPNKFRSSSTTAVANPTLSSLDVKRI--LFQKITDRG 72
Query: 440 SSLQKQVSSTEKTAISTLENFCEAISKLQENYIAAEELQSILPSTGINLLDEEFQKIVTD 499
LQK + T +N ++ EL+ I+ + L E+FQ ++
Sbjct: 73 DELQKAFQ-----LLDTGQNLT----------VSKSELRRIITDFLMPLTREQFQDVLAQ 117
Query: 500 TSRNENGMVE----------LDDFVNALAK--------------------ERSFPECNAL 529
+ +G V +D ++N + + E+ F +
Sbjct: 118 IPLSTSGTVPYLAFLSRFGGIDLYINGIKRGGGNEMNCCRTLRELEIQVGEKVFKNIKTV 177
Query: 530 PGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTM 589
+ ID K V ++L L+ F + L E++K ++ + V++ F+ +
Sbjct: 178 MKAFELIDVNKTGLVRPQELRRVLETFCMKLRDEEYEKFSKHYNIHKDTAVDYNVFLKNL 237
Query: 590 MSNTE-----CFSEKLVLPDAIETLDDLRKE---TVSVSDLWNTLSSLNSNLKKDEFLAA 641
N + C + V + + + ++ + S D+W N +L + E
Sbjct: 238 SINNDLNLRYCMGNQEVSLENQQAKNSKKERLLGSASSEDIWR-----NYSLDEIERNFC 292
Query: 642 LELVTVDEGDKVQFEEFAKVVRNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNV 701
L+L + E++++ + A D +G ++ L+ L
Sbjct: 293 LQL-----------------------SKSYEKVEKALSAGDPCKGGYVSFNYLKIVLDTF 329
Query: 702 GIKSPKEEVEKILQSDFVSEDNMVNIKDCMRALRDTQKFS----------NYIDFRKEAS 751
+ P+ ++++ + +N K + + + Q N I+ R E+
Sbjct: 330 VYQIPRRIFIQLMKRFGLKATTKINWKQFLTSFHEPQGLQVSSKGPLTKRNSINSRNESH 389
Query: 752 N----LKLPKVNE-----IKEAANILSHVDNGKIGIPDLEHALKCLNVNLTEEDFNEALN 802
KL + E +K+A I++ +G I + + L C+ V L++ +F E +
Sbjct: 390 KENIITKLFRHTEDHSASLKKALLIINTKPDGPITREEFRYILNCMAVKLSDSEFKELMQ 449
Query: 803 CCNVSDNMEVDLKDFLMKMKESPHFQKS 830
+ D V+ F+ ++E+ +K+
Sbjct: 450 MLDPGDTGVVNTSMFIDLIEENCRMRKT 477
Score = 33.1 bits (74), Expect = 1.3
Identities = 22/97 (22%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 528 ALPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFID 587
+L + I+ D + E+ L + LS EFK++ ++ + G+T VN FID
Sbjct: 407 SLKKALLIINTKPDGPITREEFRYILNCMAVKLSDSEFKELMQMLDPGDTGVVNTSMFID 466
Query: 588 TMMSN------TECFSEKLVLPDAIETLDDLRKETVS 618
+ N + C K A ++++++ +T++
Sbjct: 467 LIEENCRMRKTSPCTDAKTPFLLAWDSVEEIVHDTIT 503
Score = 32.0 bits (71), Expect = 2.9
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 442 LQKQVSSTEKTAISTLENFCEAISKLQENYIAAEELQSILPSTGINLLDEEFQKIVTDTS 501
L K V+S ENF ++ N I+ EE ++I L DE+F ++ +
Sbjct: 1170 LHKAVTSHYHAITQEFENF----DTMKTNTISREEFRAICNRRVQILTDEQFDRLWNEMP 1225
Query: 502 RNENGMVELDDFVNALAKE 520
N G ++ DF++ + E
Sbjct: 1226 VNAKGRLKYPDFLSRFSSE 1244
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 39.7 bits (91), Expect = 0.014
Identities = 89/456 (19%), Positives = 177/456 (38%), Gaps = 57/456 (12%)
Query: 45 TIEKEISPEIRSLSPEYKKIFETSIIFCGEEKSSDFSGEKKVGRKSLQVQQHSKRTEIIP 104
T+ KE+ +I SL+ E K F + EE + KK R+ + + K+ E
Sbjct: 580 TMLKELEGKINSLTEE-KDDFINKLKNSHEEMDNF---HKKCEREERLILELGKKVEQTI 635
Query: 105 PFLKLSKEKVTRKENSLCKLPNQYSVH--KTSSPLCTSSAITREKEMLSNLYMTLYDEVT 162
+ ++KV L + + + K + ++ +KE+LS +LY+E
Sbjct: 636 QYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENN 695
Query: 163 HGYLHSKELSALHKACKIFSKIRSGKIYVNDLPVILCILRISISDLE-MRQALKTVDIDA 221
K+LS + ++F + I + + L++ + + + + + L+ +
Sbjct: 696 KLSSEKKQLS---RDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQK 752
Query: 222 F--QDALKIFCRIKGGRVSTD----DVFAVLDSMGIPINREILEEVTKHTYIDSNHMVDI 275
+ L F + G VS D DV VL ++G + + I EE + ++++
Sbjct: 753 LFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAK-INEEKCNLAFQRDEKVLEL 811
Query: 276 GDIIFTLNE-----------LQEQYEDVSITEGSPLNEITSDRKLSSVAGCYLKYKKKNS 324
I L E L YE + L EI S+ K +
Sbjct: 812 EKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSE---------------KEA 856
Query: 325 LSSKLPEPSISKKLNKKSNQYYSKIMENDDLESKRPKNTWQIRKFLGGVGSSNVGVQEPY 384
L S L E + + + NQ + +++ +++ K+ K ++ +
Sbjct: 857 LQSDLLEMKNANEKTRLENQ--NLLIQVEEVSQTCSKSEIHNEK------------EKCF 902
Query: 385 SKNGINFKKHSEKGEIHDSKSKPQSLKSSTSLSKSLDKSDISSIPKLQKPAVRKHSSLQK 444
K N K E+ E+ D +++ LK S + S S+ +SS+ +L++ ++
Sbjct: 903 IKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKE 962
Query: 445 QVSSTEKTAISTLENFCEAISKLQENYIAAEELQSI 480
+ K + ++ E S +E EEL+S+
Sbjct: 963 KEEKINKIKLVAVKAKKELDSSRKETQTVKEELESL 998
Score = 38.5 bits (88), Expect = 0.031
Identities = 134/729 (18%), Positives = 270/729 (37%), Gaps = 137/729 (18%)
Query: 320 KKKNSLSSKLPEPSISKKLNKKSNQYYSKIM-----ENDDLESKRPKNTWQIRKFLGGVG 374
K+K+ KL + + K+ + + S + EN+ L S++ + + + FL
Sbjct: 657 KEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLS--- 713
Query: 375 SSNVGVQEPYSKNGINFKKHSEKGEIHDSKSKPQSLKSSTSLSKSLDKSDISSI-PKLQK 433
K + K+H + E K ++ +L+K L+ + + K Q
Sbjct: 714 ----------QKEDVILKEHITQLE----KKLQLMVEEQDNLNKLLENEQVQKLFVKTQL 759
Query: 434 PAVRKHSSLQKQVSSTEKTAISTLENFCEAISKL-------------------------- 467
K + S EK ++ L+ E+++K+
Sbjct: 760 YGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQ 819
Query: 468 QENYIAAEELQSILPSTGIN--LLDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPE 525
+E+ + EEL+S+L LL +E ++I ++ ++ ++E+ + A E++ E
Sbjct: 820 EESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKN-----ANEKTRLE 874
Query: 526 CNALPGVIKAIDKIKDKNVDYEDLNTCL----QNFGIYLSKPEFK--------------- 566
L ++ + + K+ + + C +N L + E +
Sbjct: 875 NQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAK 934
Query: 567 ----------KITELTEAGETKKVNFKEFIDTMMSNTECFSEKLVLPDAIETLDDLRKET 616
+ EL E E + KE + KLV A + LD RKET
Sbjct: 935 SPSVKNDPLSSVKELEEKIENLEKECKE------KEEKINKIKLVAVKAKKELDSSRKET 988
Query: 617 VSVSDLWNTLSSLNSNLKKDEFLAAL-ELVTVDEGDK---VQFEEFAKVVRNMRDAA--- 669
+V + L SL S +KD+ A++ +L+ E K +++E+ ++ + ++ A
Sbjct: 989 QTVKE---ELESLRS--EKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNF 1043
Query: 670 --RLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSEDNMVNI 727
R+E+L L L+ + I N ED L + ++ ++ + MV+
Sbjct: 1044 EHRIEDLTR-QLRNSTLQCETINSDN-EDLLARIETLQSNAKLLEVQILEVQRAKAMVDK 1101
Query: 728 KDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGK----------IG 777
+ L+ QK + E L++ E K+ + ++ K +
Sbjct: 1102 ELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNME 1161
Query: 778 IPDLEHALKCLNVNLTE-----EDFNEALNCCNVSDNMEVDLKDFLMKMKESPHFQKSKA 832
I D E +K LN LT ED + + + + L++ + ++ S + K
Sbjct: 1162 IADYERLMKELNQKLTNKNNKIEDLEQEI---KIQKQKQETLQEEITSLQSSVQQYEEKN 1218
Query: 833 TQILLATTQILQNDLVDVSDLKTLLMDKDLHTANAILTVMLRHVPEHESGKVSIQEFMTK 892
T+I Q+L V K L K T + IL L+ E E+ + ++ + +
Sbjct: 1219 TKI----KQLL------VKTKKELADSKQAETDHLILQASLK--GELEASQQQVEVYKIQ 1266
Query: 893 LSDILTIPKAAGKFYLICTYCPDLERQAVVYMLKTIQDSIVKAQVSKKQYNMNIKQHKIS 952
L++I + + A + +Q+ A+ + + +K+
Sbjct: 1267 LAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVR 1326
Query: 953 LHNFCLNSK 961
+HN K
Sbjct: 1327 VHNVLKQQK 1335
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 39.7 bits (91), Expect = 0.014
Identities = 123/604 (20%), Positives = 239/604 (39%), Gaps = 91/604 (15%)
Query: 146 EKEMLSNLYMTLYDEVTHGYLHSKELSALHKAC----KIFSKIRSGKIYVNDLPVILCIL 201
E + L M L + ++ EL AL + K+ S++ K ++D+ +
Sbjct: 287 ELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARV 346
Query: 202 RISISDLEMRQALKTVDIDAFQDALKIFCRIKGGRVSTDDVFAVLDSMGIPINREILEEV 261
D ++ KT+ D +++G R +D + L+ + + + L ++
Sbjct: 347 EELKEDNQVLLETKTMLED----------QLEGTRARSDKLHE-LEKENLQLKAK-LHDM 394
Query: 262 TKHTYIDSNHMVDIGDIIFTLNELQEQYEDVSITEGSPLNEITSDRKLSSVAGCYLKYKK 321
+D + ++ + TL Q+Q D S+ G L +I+ +LS
Sbjct: 395 EMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEA--------- 445
Query: 322 KNSLSSKLPEPSISKKLNKKSNQYYSKI-MENDDLESKRPKNTWQIRKFLGGVGSSNVGV 380
P+ S+ ++N+ ++ K+ MEN L K ++R + V + +
Sbjct: 446 --------PQKSLGHEVNELTSSRLLKLEMENQSLT----KTVEELRTTVDSVEGNASKI 493
Query: 381 QEPYSKNGINFKKHSEKGEIHDSK--SKPQSLKSSTSLSKSLDKSDIS---SIPKLQKPA 435
+ +N ++ S+K EI +++ + QSL++ +LSK L K +I L++ +
Sbjct: 494 LKMEKEN----QRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENS 549
Query: 436 VRKHSSLQKQVSSTEKTAISTLENFCEAISKLQENYIAAEE--LQSILPSTGINLLDEEF 493
R+ L+++ +T +S+L + ++ + I E L + T L EF
Sbjct: 550 ERQIKILEQENEHLNQT-VSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608
Query: 494 QK--IVTDTSR-NENG--MVELDDFVNALAKERSF--PECNALPGVIKAIDKIKDKNVDY 546
+K I + E G EL++ ++ L KE + L + I+ ++ +N +
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL 668
Query: 547 EDLNTCLQNFGIYLSKPEFKKIT------------------ELTEAGETKKVNFKEFIDT 588
E N L+ + FK +T EL E+ K +
Sbjct: 669 ERENRKLKK-----TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 723
Query: 589 MMSNTECFSEKLVLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVD 648
+ N E SEK L +E L K+T + + L N L+K LE +
Sbjct: 724 QLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK-----TLE----N 774
Query: 649 EGDKVQFEEFAKVVRNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKE 708
K+Q E M + + L+E+ +++ LE K+LE ++ K+
Sbjct: 775 SNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ--ETSQLEKDKK 832
Query: 709 EVEK 712
++EK
Sbjct: 833 QLEK 836
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 39.7 bits (91), Expect = 0.014
Identities = 123/604 (20%), Positives = 239/604 (39%), Gaps = 91/604 (15%)
Query: 146 EKEMLSNLYMTLYDEVTHGYLHSKELSALHKAC----KIFSKIRSGKIYVNDLPVILCIL 201
E + L M L + ++ EL AL + K+ S++ K ++D+ +
Sbjct: 287 ELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARV 346
Query: 202 RISISDLEMRQALKTVDIDAFQDALKIFCRIKGGRVSTDDVFAVLDSMGIPINREILEEV 261
D ++ KT+ D +++G R +D + L+ + + + L ++
Sbjct: 347 EELKEDNQVLLETKTMLED----------QLEGTRARSDKLHE-LEKENLQLKAK-LHDM 394
Query: 262 TKHTYIDSNHMVDIGDIIFTLNELQEQYEDVSITEGSPLNEITSDRKLSSVAGCYLKYKK 321
+D + ++ + TL Q+Q D S+ G L +I+ +LS
Sbjct: 395 EMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEA--------- 445
Query: 322 KNSLSSKLPEPSISKKLNKKSNQYYSKI-MENDDLESKRPKNTWQIRKFLGGVGSSNVGV 380
P+ S+ ++N+ ++ K+ MEN L K ++R + V + +
Sbjct: 446 --------PQKSLGHEVNELTSSRLLKLEMENQSLT----KTVEELRTTVDSVEGNASKI 493
Query: 381 QEPYSKNGINFKKHSEKGEIHDSK--SKPQSLKSSTSLSKSLDKSDIS---SIPKLQKPA 435
+ +N ++ S+K EI +++ + QSL++ +LSK L K +I L++ +
Sbjct: 494 LKMEKEN----QRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENS 549
Query: 436 VRKHSSLQKQVSSTEKTAISTLENFCEAISKLQENYIAAEE--LQSILPSTGINLLDEEF 493
R+ L+++ +T +S+L + ++ + I E L + T L EF
Sbjct: 550 ERQIKILEQENEHLNQT-VSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608
Query: 494 QK--IVTDTSR-NENG--MVELDDFVNALAKERSF--PECNALPGVIKAIDKIKDKNVDY 546
+K I + E G EL++ ++ L KE + L + I+ ++ +N +
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL 668
Query: 547 EDLNTCLQNFGIYLSKPEFKKIT------------------ELTEAGETKKVNFKEFIDT 588
E N L+ + FK +T EL E+ K +
Sbjct: 669 ERENRKLKK-----TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 723
Query: 589 MMSNTECFSEKLVLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVD 648
+ N E SEK L +E L K+T + + L N L+K LE +
Sbjct: 724 QLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK-----TLE----N 774
Query: 649 EGDKVQFEEFAKVVRNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKE 708
K+Q E M + + L+E+ +++ LE K+LE ++ K+
Sbjct: 775 SNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ--ETSQLEKDKK 832
Query: 709 EVEK 712
++EK
Sbjct: 833 QLEK 836
>gi|4501893 actinin, alpha 2 [Homo sapiens]
Length = 894
Score = 39.3 bits (90), Expect = 0.018
Identities = 23/76 (30%), Positives = 34/76 (44%)
Query: 518 AKERSFPECNALPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGET 577
AK + + N D+ K+ +D+ED CL + G L + EF +I L +
Sbjct: 747 AKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQ 806
Query: 578 KKVNFKEFIDTMMSNT 593
V F+ FID M T
Sbjct: 807 GTVTFQSFIDFMTRET 822
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 38.9 bits (89), Expect = 0.024
Identities = 110/564 (19%), Positives = 219/564 (38%), Gaps = 65/564 (11%)
Query: 179 KIFSKIRSGKIYVNDLPVILCILRISISDLEMRQALKTVDIDAFQDAL--------KIFC 230
++ +++ K V DL + I+ DLE + L+ I + +L K+
Sbjct: 426 ELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQR 485
Query: 231 RIKGGRVSTDDVFAVLDSMGIPINREILEEVTKHTYIDSNHMVDIGDIIFTLNELQE--- 287
++ RV+T + + + + + E ++SN GD+ +L+ LQE
Sbjct: 486 ELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPA--GDVDMSLSLLQEISS 543
Query: 288 ------------QYEDVSITEGSPLNEITSDRKLSSVAGCYLKYKKKN-SLSSKLPEPSI 334
Q E S+ E E T +++ ++ K K+N SL SKL
Sbjct: 544 LQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH--- 600
Query: 335 SKKLNKKSNQYYSKIMENDDLESKRPKNTWQIRKFLGGVGSSNVGVQEPYSKNGINFKKH 394
+ K N + +E ++ ++ F G+G+ E K
Sbjct: 601 ANKENSDVIALWKSKLETAIASHQQAMEELKV-SFSKGLGTETAEFAE--------LKTQ 651
Query: 395 SEKGEIHDSKSKPQSLKSSTSLSKSLDKSDISSI-PKLQKPAVRKHSSLQKQVSSTEKTA 453
EK + D + + ++L++ ++ ++ ++ KL K K +SL+ S +K
Sbjct: 652 IEKMRL-DYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAE 710
Query: 454 ISTLENFCEAISKLQENYIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDF 513
L + ++KLQE I +EL+ + N + + E +++LD
Sbjct: 711 DQHLVEMEDTLNKLQEAEIKVKELEVL--QAKCNEQTKVIDNFTSQLKATEEKLLDLDAL 768
Query: 514 VNALAKERSFPECNALPGVIKAIDK-IKDKNVDYEDLNTCLQNFGIYLSKPEFKKIT--- 569
A ++ +S E L ++A +K IK ++ ++ + L E K
Sbjct: 769 RKASSEGKS--EMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQE 826
Query: 570 ELTEAGETKKVNFKEFIDTMMSNTECFSEKLVLPDAI-ETLDDLRKETVSVSDLWNTLSS 628
L+E + K+ KE E E + + ++ ET++ L ++ + L + L
Sbjct: 827 NLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEK 886
Query: 629 LNSNL------------KKDEFLAALELVTVDEGDKVQFE-EFAKVVRNMRDAARLEELQ 675
L NL ++++ + A E + D + ++ + + + M D RL+E
Sbjct: 887 LRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD 946
Query: 676 EVVLAADLLEGDMIAG---KNLED 696
L L + + A K++ED
Sbjct: 947 VEELQLKLTKANENASFLQKSIED 970
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 38.5 bits (88), Expect = 0.031
Identities = 79/330 (23%), Positives = 143/330 (43%), Gaps = 42/330 (12%)
Query: 364 WQIRKFLGGVGSSNVGVQEPYSKNGINFKKHSEKGEIHDSKSKPQSLKSSTSLSKSLDKS 423
W IR F+G N + Y K K + E+ K + T L ++L+KS
Sbjct: 816 WNIRAFMG---VKNWPWMKLYFKIKPLLKSAEREKEMASMKEE------FTRLKEALEKS 866
Query: 424 DI--SSIPKLQKPAVRKHSSLQKQVSSTEKTAISTLENFCEAI--SKLQENYIAAEELQS 479
+ + + +++ + LQ QV + E+ ++ E C+ + +K+Q E +
Sbjct: 867 EARRKELEEKMVSLLQEKNDLQLQVQA-EQDNLADAEERCDQLIKNKIQLEAKVKEMNER 925
Query: 480 ILPSTGINL-LDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPE------CNALPGV 532
+ +N L + +K+ + S + + +L+ + + KE+ E + G+
Sbjct: 926 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 985
Query: 533 IKAIDKI-KDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTMMS 591
+ I K+ K+K E L + + E K+ LT+A KV ++ +D +
Sbjct: 986 DEIIAKLTKEKKALQEAHQQALDDL-----QAEEDKVNTLTKA----KVKLEQQVDDLEG 1036
Query: 592 NTECFSEKLVLPD---AIETLD-DLRKETVSVSDLWNTLSSLNSNLKKDEF-LAALELVT 646
+ E EK V D A L+ DL+ S+ DL N L+ LKK +F L AL
Sbjct: 1037 SLE--QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
Query: 647 VDEGDKVQFEEFAKVVRNMRDAARLEELQE 676
DE + + K ++ ++ AR+EEL+E
Sbjct: 1095 EDE--QALGSQLQKKLKELQ--ARIEELEE 1120
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 38.5 bits (88), Expect = 0.031
Identities = 28/124 (22%), Positives = 57/124 (45%), Gaps = 20/124 (16%)
Query: 694 LEDFLRNVGIKSPKEEVEKILQSDFVSEDNMVNIKDCMRALRDTQKFSNYIDFRKEASNL 753
L++ L +VG EE +KI + V++D ++ ++ M+ L+D +K
Sbjct: 25 LQEGLEDVGAIQSLEEAKKIFTTGDVNKDGKLDFEEFMKYLKDHEK-------------- 70
Query: 754 KLPKVNEIKEAANILSHVDNGKIGIPDLEHALKCLNVNLTEEDFNEALNCCNVSDNMEVD 813
++K A L ++GKI ++ +L+ L + ++E+ L +V M VD
Sbjct: 71 ------KMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVD 124
Query: 814 LKDF 817
++
Sbjct: 125 WNEW 128
Score = 37.4 bits (85), Expect = 0.069
Identities = 29/123 (23%), Positives = 58/123 (47%), Gaps = 6/123 (4%)
Query: 536 IDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTMMSNTEC 595
+D KD +D +L L++ G S E KKI + + K++F+EF+ + +
Sbjct: 12 LDYNKDGTLDIFELQEGLEDVGAIQSLEEAKKIFTTGDVNKDGKLDFEEFMKYLKDH--- 68
Query: 596 FSEKLVLPDAIETLDDLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQF 655
+K+ L A ++LD + S++ +L +L + + + L+ + VD V +
Sbjct: 69 -EKKMKL--AFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDW 125
Query: 656 EEF 658
E+
Sbjct: 126 NEW 128
>gi|113722133 senataxin [Homo sapiens]
Length = 2677
Score = 38.1 bits (87), Expect = 0.040
Identities = 86/386 (22%), Positives = 159/386 (41%), Gaps = 47/386 (12%)
Query: 292 VSITEGSPLNEITSDRKLSSVAGCYLKYKKKNSLSSKLPEPSISKKLNKKSNQYYSKI-- 349
V +T ++ + +++ S G K +K+ + P+ SK+ K + K
Sbjct: 606 VDLTSACKISPASYNKEESEQMG---KTSRKDMHCLEASSPTFSKEPMKVQDSVLIKADN 662
Query: 350 -MENDDLESKRPKNTWQIRKFLGGV----GSSNVGVQEPYSKNGINFKKHSEKGEIHDSK 404
+E D+ E K+ L G S N+ + + I+ +K EI S
Sbjct: 663 TIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEI--SS 720
Query: 405 SKPQSLKSSTSLSKSLDKSDISSIPKLQKPAVRKHSSLQKQVSSTEKTAIS--TLENFCE 462
P+ S + D+ I S L + +L+K +S E ++ L +
Sbjct: 721 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSST---DALEKVSTSNEDFSLKDDALAKTSK 777
Query: 463 AISKLQENYIAA--------EELQSILPSTGINLLDEEF--QKIVTDTSRNENGMVELDD 512
+K+Q++ I A + +S L INL DE I + SR + G+ + D
Sbjct: 778 RKTKVQKDEICAKLSHVIKKQHRKSTLVDNTINL-DENLTVSNIESFYSRKDTGVQKGDG 836
Query: 513 FVNALAKERSFPECNALPGVIKAIDKI--KDKNVDYEDL-------NTC-LQNFGIYLSK 562
F++ L+ + S + G K+ + + K+K + E+L N C +Q F ++
Sbjct: 837 FIHNLSLDPS-GVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEF--HVDG 893
Query: 563 PEFKKITELTEAGETKKVNFKEFIDTMMSNTECFSEKLVLPDAIETLDDLRKETVSVSDL 622
E TE+T A E K FK+ +M+ E E++ ++ + R++ +S
Sbjct: 894 KELIPFTEMTNASEKKSSPFKD----LMTVPESRDEEMSNSTSVIYSNLTREQAPDISPK 949
Query: 623 WNTL--SSLNSNLKKDEFLAALELVT 646
+TL S ++ +L K LA ++T
Sbjct: 950 SDTLTDSQIDRDLHKLSLLAQASVIT 975
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 38.1 bits (87), Expect = 0.040
Identities = 63/315 (20%), Positives = 120/315 (38%), Gaps = 42/315 (13%)
Query: 611 DLRKETVSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVVRNMRDAAR 670
DL+ S+ DL N + LKK EF + +D+ ++V +F K ++ ++ AR
Sbjct: 1062 DLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDD-EQVHSLQFQKKIKELQ--AR 1118
Query: 671 LEELQEVVLAADLLEGDMIAGKNLEDFLRNV-----------GIKSPKEEVEKILQSDFV 719
+EEL+E + A L + K D R + G S + E+ K +++F
Sbjct: 1119 IEELEEEIEAEHTLRAKI--EKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQ 1176
Query: 720 S-----EDNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNG 774
E+ + + LR Q + + ++ NL+ K KE + + +D+
Sbjct: 1177 KMRRDLEEATLQHEATAATLRKKQA-DSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDM 1235
Query: 775 KIGIPDLEHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDFL---------------- 818
I L + N+ T + + D + L L
Sbjct: 1236 ASNIEALSKSKS--NIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSH 1293
Query: 819 -MKMKESPHFQKSKATQILLATTQILQNDLVDVSDLKTLLMDKDLHTANAILTVMLRHVP 877
++ KES Q +K+ Q L + L+ + + + K M L ++ ++
Sbjct: 1294 RVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKN-AMAHALQSSRHDCDLLREQYE 1352
Query: 878 EHESGKVSIQEFMTK 892
E + K +Q ++K
Sbjct: 1353 EEQEAKAELQRALSK 1367
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,642,013
Number of Sequences: 37866
Number of extensions: 1395488
Number of successful extensions: 4213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 116
Number of HSP's that attempted gapping in prelim test: 3898
Number of HSP's gapped (non-prelim): 412
length of query: 973
length of database: 18,247,518
effective HSP length: 112
effective length of query: 861
effective length of database: 14,006,526
effective search space: 12059618886
effective search space used: 12059618886
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.