Search of human proteins with 31377575

Search of human proteins with 31377575

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31377575 ENTH domain containing 1 [Homo sapiens]
         (607 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31377575 ENTH domain containing 1 [Homo sapiens]                  1205   0.0  
gi|156671217 epsin 2 isoform a [Homo sapiens]                         218   2e-56
gi|156671215 epsin 2 isoform b [Homo sapiens]                         218   2e-56
gi|41350201 epsin 1 isoform c [Homo sapiens]                          211   1e-54
gi|194248095 epsin 1 isoform b [Homo sapiens]                         211   1e-54
gi|194272148 epsin 1 isoform a [Homo sapiens]                         211   1e-54
gi|157388929 epsin 3 [Homo sapiens]                                   210   3e-54
gi|7661968 epsin 4 [Homo sapiens]                                     139   6e-33
gi|119393876 NLR family, apoptosis inhibitory protein isoform 2 ...    37   0.069
gi|91982772 mucin 17 [Homo sapiens]                                    36   0.12 
gi|42718017 retinoblastoma binding protein 8 isoform b [Homo sap...    35   0.20 
gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sap...    35   0.20 
gi|4506441 retinoblastoma binding protein 8 isoform a [Homo sapi...    35   0.20 
gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]                  34   0.34 
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]                  34   0.34 
gi|167736355 mucin 4 isoform a [Homo sapiens]                          33   0.99 
gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]             33   0.99 
gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Ho...    32   1.7  
gi|169171850 PREDICTED: similar to intestinal mucin MUC3B [Homo ...    32   2.2  
gi|151301154 mucin 6, gastric [Homo sapiens]                           32   2.2  
gi|4758696 mitogen-activated protein kinase kinase kinase 13 [Ho...    32   2.2  
gi|50811889 centrosomal protein 192kDa [Homo sapiens]                  32   2.2  
gi|22325364 ubiquitin associated protein 2 [Homo sapiens]              31   2.9  
gi|39930471 hypothetical protein LOC84190 [Homo sapiens]               31   2.9  
gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]              31   3.8  
gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]               31   3.8  
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    30   4.9  
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...    30   4.9  
gi|46240864 sperm associated antigen 17 [Homo sapiens]                 30   4.9  
gi|58743369 hypothetical protein LOC139231 [Homo sapiens]              30   4.9  

>gi|31377575 ENTH domain containing 1 [Homo sapiens]
          Length = 607

 Score = 1205 bits (3118), Expect = 0.0
 Identities = 607/607 (100%), Positives = 607/607 (100%)

Query: 1   MAFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHR 60
           MAFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHR
Sbjct: 1   MAFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHR 60

Query: 61  LNDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYI 120
           LNDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYI
Sbjct: 61  LNDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYI 120

Query: 121 REKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGSSNSLTACTSAPTPDIS 180
           REKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGSSNSLTACTSAPTPDIS
Sbjct: 121 REKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGSSNSLTACTSAPTPDIS 180

Query: 181 ASEKKYKLPKFGRLHNKRNVCKAGLKQEHCQDVHLPTETMLSQETLPLKIHGWKSTEDLM 240
           ASEKKYKLPKFGRLHNKRNVCKAGLKQEHCQDVHLPTETMLSQETLPLKIHGWKSTEDLM
Sbjct: 181 ASEKKYKLPKFGRLHNKRNVCKAGLKQEHCQDVHLPTETMLSQETLPLKIHGWKSTEDLM 240

Query: 241 TFLDDDPELPLLATPPSIVSPITCLSEAEEVCNLSGADAVPTLSENSPSGQRDVSLDKRS 300
           TFLDDDPELPLLATPPSIVSPITCLSEAEEVCNLSGADAVPTLSENSPSGQRDVSLDKRS
Sbjct: 241 TFLDDDPELPLLATPPSIVSPITCLSEAEEVCNLSGADAVPTLSENSPSGQRDVSLDKRS 300

Query: 301 DGIFTNTVTENLLETPLEKQSAAEGLKTLTILPACWSSKEEFISPDLRVSKSDSTFHNQA 360
           DGIFTNTVTENLLETPLEKQSAAEGLKTLTILPACWSSKEEFISPDLRVSKSDSTFHNQA
Sbjct: 301 DGIFTNTVTENLLETPLEKQSAAEGLKTLTILPACWSSKEEFISPDLRVSKSDSTFHNQA 360

Query: 361 SVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTTTRVSTASEGASSFSPL 420
           SVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTTTRVSTASEGASSFSPL
Sbjct: 361 SVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTTTRVSTASEGASSFSPL 420

Query: 421 SMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASRGPVSS 480
           SMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASRGPVSS
Sbjct: 421 SMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASRGPVSS 480

Query: 481 DVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQFIPLSCSGFQSTKDFPQ 540
           DVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQFIPLSCSGFQSTKDFPQ
Sbjct: 481 DVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQFIPLSCSGFQSTKDFPQ 540

Query: 541 EPEAKNSISVLLREVKRAIARLHEDLSTVIQELNVINNILMSMSLNSSQISQSSQVPQSS 600
           EPEAKNSISVLLREVKRAIARLHEDLSTVIQELNVINNILMSMSLNSSQISQSSQVPQSS
Sbjct: 541 EPEAKNSISVLLREVKRAIARLHEDLSTVIQELNVINNILMSMSLNSSQISQSSQVPQSS 600

Query: 601 EGSSDQI 607
           EGSSDQI
Sbjct: 601 EGSSDQI 607


>gi|156671217 epsin 2 isoform a [Homo sapiens]
          Length = 584

 Score =  218 bits (554), Expect = 2e-56
 Identities = 108/191 (56%), Positives = 137/191 (71%), Gaps = 5/191 (2%)

Query: 2   AFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRL 61
           + RRQ+KN V NYS+AEIKVREATSNDPWGPSSSLM +I+DLT+N ++ SEIM+M+W RL
Sbjct: 5   SIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRL 64

Query: 62  NDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIR 121
           NDHGKNWRHVYK+LTL+DYLIK GS++V Q CRE    +QTLKDFQ+ID  GKDQG  +R
Sbjct: 65  NDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVR 124

Query: 122 EKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGSSNSLTACTSAPTPDISA 181
           EKSKQ++ LL DE  L  ER  A +T++R +            SN +T    +  P++S 
Sbjct: 125 EKSKQLVALLKDEERLKAERAQALKTKERMAQVATGM-----GSNQITFGRGSSQPNLST 179

Query: 182 SEKKYKLPKFG 192
           S  + +  K G
Sbjct: 180 SHSEQEYGKAG 190


>gi|156671215 epsin 2 isoform b [Homo sapiens]
          Length = 641

 Score =  218 bits (554), Expect = 2e-56
 Identities = 108/191 (56%), Positives = 137/191 (71%), Gaps = 5/191 (2%)

Query: 2   AFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRL 61
           + RRQ+KN V NYS+AEIKVREATSNDPWGPSSSLM +I+DLT+N ++ SEIM+M+W RL
Sbjct: 5   SIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRL 64

Query: 62  NDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIR 121
           NDHGKNWRHVYK+LTL+DYLIK GS++V Q CRE    +QTLKDFQ+ID  GKDQG  +R
Sbjct: 65  NDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVR 124

Query: 122 EKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGSSNSLTACTSAPTPDISA 181
           EKSKQ++ LL DE  L  ER  A +T++R +            SN +T    +  P++S 
Sbjct: 125 EKSKQLVALLKDEERLKAERAQALKTKERMAQVATGM-----GSNQITFGRGSSQPNLST 179

Query: 182 SEKKYKLPKFG 192
           S  + +  K G
Sbjct: 180 SHSEQEYGKAG 190


>gi|41350201 epsin 1 isoform c [Homo sapiens]
          Length = 550

 Score =  211 bits (538), Expect = 1e-54
 Identities = 98/163 (60%), Positives = 129/163 (79%)

Query: 2   AFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRL 61
           + RRQ+KN V NYS+AEIKVREATSNDPWGPSSSLM +I+DLT+N ++ SEIM+M+W RL
Sbjct: 5   SLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRL 64

Query: 62  NDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIR 121
           NDHGKNWRHVYK++TLM+YLIK GS++V Q C+E    +QTLKDFQ++D  GKDQG  +R
Sbjct: 65  NDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVR 124

Query: 122 EKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGS 164
           EK+KQ++ LL DE  L +ER  A +T+++ + +   S   +GS
Sbjct: 125 EKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGS 167


>gi|194248095 epsin 1 isoform b [Homo sapiens]
          Length = 576

 Score =  211 bits (538), Expect = 1e-54
 Identities = 98/163 (60%), Positives = 129/163 (79%)

Query: 2   AFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRL 61
           + RRQ+KN V NYS+AEIKVREATSNDPWGPSSSLM +I+DLT+N ++ SEIM+M+W RL
Sbjct: 5   SLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRL 64

Query: 62  NDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIR 121
           NDHGKNWRHVYK++TLM+YLIK GS++V Q C+E    +QTLKDFQ++D  GKDQG  +R
Sbjct: 65  NDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVR 124

Query: 122 EKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGS 164
           EK+KQ++ LL DE  L +ER  A +T+++ + +   S   +GS
Sbjct: 125 EKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGS 167


>gi|194272148 epsin 1 isoform a [Homo sapiens]
          Length = 662

 Score =  211 bits (538), Expect = 1e-54
 Identities = 98/163 (60%), Positives = 129/163 (79%)

Query: 2   AFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRL 61
           + RRQ+KN V NYS+AEIKVREATSNDPWGPSSSLM +I+DLT+N ++ SEIM+M+W RL
Sbjct: 116 SLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRL 175

Query: 62  NDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIR 121
           NDHGKNWRHVYK++TLM+YLIK GS++V Q C+E    +QTLKDFQ++D  GKDQG  +R
Sbjct: 176 NDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVR 235

Query: 122 EKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGS 164
           EK+KQ++ LL DE  L +ER  A +T+++ + +   S   +GS
Sbjct: 236 EKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGS 278


>gi|157388929 epsin 3 [Homo sapiens]
          Length = 632

 Score =  210 bits (534), Expect = 3e-54
 Identities = 104/165 (63%), Positives = 125/165 (75%), Gaps = 1/165 (0%)

Query: 2   AFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRL 61
           A RRQVKN V NYS+AEIKVREATSNDPWGP SSLM +I+DLTFNT++ +E+M MLW RL
Sbjct: 5   ALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRL 64

Query: 62  NDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIR 121
           ND GKNWRHVYK+LTL+DYL+K GS++V   CRE    +QTLKDFQ+ID  GKDQG  +R
Sbjct: 65  NDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVR 124

Query: 122 EKSKQVITLLMDEPLLCKEREVACRTRQRTS-HSILFSKRQLGSS 165
           EK KQV+ LL DE  L +ER  A +T++R +   I     QLG S
Sbjct: 125 EKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFS 169


>gi|7661968 epsin 4 [Homo sapiens]
          Length = 625

 Score =  139 bits (351), Expect = 6e-33
 Identities = 69/143 (48%), Positives = 98/143 (68%), Gaps = 1/143 (0%)

Query: 9   NFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHR-LNDHGKN 67
           N V NYS+ E KVREAT++DPWGPS  LM +I+  TF      E+MNMLW R L D+ KN
Sbjct: 16  NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75

Query: 68  WRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIREKSKQV 127
           WR VYKSL L+ YLI+NGS++V+   RE   +L++L+++  +DE GKDQG  IR+K K++
Sbjct: 76  WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135

Query: 128 ITLLMDEPLLCKEREVACRTRQR 150
           +    D+  L +ER+ A + + +
Sbjct: 136 VEFAQDDDRLREERKKAKKNKDK 158


>gi|119393876 NLR family, apoptosis inhibitory protein isoform 2
           [Homo sapiens]
          Length = 1241

 Score = 36.6 bits (83), Expect = 0.069
 Identities = 18/50 (36%), Positives = 26/50 (52%)

Query: 487 SLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQFIPLSCSGFQSTK 536
           SLN+  +LP    +     SHI S HW  FS+  ++ +I L C   +S K
Sbjct: 20  SLNIFSLLPTKGRTEHLFFSHILSFHWPAFSSIRLELWINLRCEFLRSKK 69


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 63/311 (20%), Positives = 113/311 (36%), Gaps = 49/311 (15%)

Query: 250 PLLATPPSIVSPITCLSEAEEVCNLSGADAVPTLSENSPSGQRDVSLDKRSDGIFTNTVT 309
           PL   P S++  ++  SEA  +     A  +P ++    S     +       I T+T T
Sbjct: 276 PLTRMPLSVMLVVS--SEASTLSTTPAATNIPVITSTEASSSPTTA---EGTSIPTSTYT 330

Query: 310 EN---LLETPLEKQSAAEG-LKTLTILPACWSSKEEFISPDLRVSKSDSTFHNQASVETL 365
           E    L  TP      A   + TL+I P   S+    ++     S   +T    + + + 
Sbjct: 331 EGSTPLTSTPASTMPVATSEMSTLSITPVDTST---LVTTSTEPSSLPTTAEATSMLTST 387

Query: 366 CLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTTTR---------------VSTA 410
               S  + +     ++  + +    S+I +D K   TT                  ST 
Sbjct: 388 LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTP 447

Query: 411 SEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAKLHH 470
           SEG++  + + +S+  +AS E S    +P+           Q  +ST       TA+++ 
Sbjct: 448 SEGSTPLTSMPVSTTPVASSEASNLSTTPV-------DSKTQVTTSTEASSSPPTAEVNS 500

Query: 471 SFASRGPVSSDVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQFIPLSCS 530
                 P S+  E +  L  + +          +   ++SS     ST  VD   P++ S
Sbjct: 501 M-----PTSTPSEGSTPLTSMSV----------STMPVASSEASTLSTTPVDTSTPVTTS 545

Query: 531 GFQSTKDFPQE 541
              S+     E
Sbjct: 546 SEASSSSTTPE 556



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 87/379 (22%), Positives = 146/379 (38%), Gaps = 69/379 (18%)

Query: 251  LLATPPSIVSPITCLSEAEEVCNLSGADAVPT--LSENSPSGQRDVSLDKRSDGIFTNTV 308
            L ATP    +P+T  +EA      +   ++PT  LSE    G   ++    S  +  N+ 
Sbjct: 2240 LSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSE----GTTPLTSIPVSHTLVANSE 2295

Query: 309  TENLLETPLEKQS-------------AAEGLKTLTILPACWSSKEEFISPDLRVSKSDST 355
               L  TP++  +              AEG    T +P   SS+    +P  R+  S + 
Sbjct: 2296 VSTLSTTPVDSNTPFTTSTEASSPPPTAEG----TSMPTSTSSEGN--TPLTRMPVSTTM 2349

Query: 356  FHNQASVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTTTRVSTASEGAS 415
                AS ET  LS +    D    +     Y +   S    DD  + T    ST SEG++
Sbjct: 2350 V---ASFETSTLSTTPA--DTSTPVT---TYSQAGSSPTTADDTSMPT----STYSEGST 2397

Query: 416  SFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASR 475
              + + +S+  + S E S H  +P+         S    +ST       TA+      + 
Sbjct: 2398 PLTSVPVSTMPVVSSEASTHSTTPV-------DTSTPVTTSTEASSSPTTAE-----GTS 2445

Query: 476  GPVSSDVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQFIPLSCSGFQST 535
             P S   E    L  + +          + + + SS  G  ST  VD   P++ S   S+
Sbjct: 2446 IPTSPPSEGTTPLASMPV----------STTPVVSSEAGTLSTTPVDTSTPMTTSTEASS 2495

Query: 536  -----KDFPQEPEAKNSISVLLREVKRAIARLHEDLSTVIQELNVINN--ILMSMSLNSS 588
                 +D        +  S LL  +  +   +    ++ +    V +N  ++ S  ++SS
Sbjct: 2496 SPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSS 2555

Query: 589  QIS-QSSQVPQS--SEGSS 604
              S + + +P S  SEGS+
Sbjct: 2556 ATSAEGTSMPTSTYSEGST 2574



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 43/204 (21%), Positives = 83/204 (40%), Gaps = 30/204 (14%)

Query: 407  VSTASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTA 466
            +STASEG++  + + +S+  +ASPE S    +P+ +     T +    S+TS +      
Sbjct: 2507 ISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAE------ 2560

Query: 467  KLHHSFASRGPVSSDVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQFIP 526
                   +  P S+  E +  L  + +          +   ++SS     ST  VD  IP
Sbjct: 2561 ------GTSMPTSTYSEGSTPLRSMPV----------STKPLASSEASTLSTTPVDTSIP 2604

Query: 527  LSCSGFQST-----KDFPQEPEAKNSISVLLREVKRAIARLHEDLSTVIQELNVINNILM 581
            ++ S   S+     KD        + +S  L  +  +   +    ++ +    V    L+
Sbjct: 2605 VTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLV 2664

Query: 582  SMSLNSSQ---ISQSSQVPQSSEG 602
            + S  +S     ++ S +P S+ G
Sbjct: 2665 TTSTGTSSSPTTAEGSSMPTSTPG 2688



 Score = 32.7 bits (73), Expect = 0.99
 Identities = 65/281 (23%), Positives = 106/281 (37%), Gaps = 45/281 (16%)

Query: 251  LLATPPSIVSPITCLSEAEEVCNLSGADAVPTLS-------------ENSPSGQRDVSLD 297
            L ATP    +P+T  +EA       G  ++PT +              N+P    + S+ 
Sbjct: 3184 LSATPVDTSTPVTTSTEATSSTTAEGT-SIPTSTPSEGMTPLTSVPVSNTPVASSEASI- 3241

Query: 298  KRSDGIFTNTVTENLLETPLEKQSAAEGLKTLTILPACWSSKEEFISPDLRVSKSDSTFH 357
                 + T  V  N   T   + S++      T +P   S+  E  +P   +  S +T  
Sbjct: 3242 -----LSTTPVDSNTPLTTSTEASSSPPTAEGTSMPT--STPSEGSTPLTSMPVSTTTV- 3293

Query: 358  NQASVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTTTRVSTASEGASSF 417
              AS ET  LS +        +          A SS  + D    T+   ST SEG++  
Sbjct: 3294 --ASSETSTLSTT------PADTSTPVTTYSQASSSPPIADG---TSMPTSTYSEGSTPL 3342

Query: 418  SPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASRG- 476
            + +S S+  + S E S    +P+       T +   LS T+ +       +  S  S G 
Sbjct: 3343 TNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEG----TSIPTSSPSEGT 3398

Query: 477  ------PVSSDVEENDSLNLLGILPNNSDSAKKNISHISSS 511
                  PVS+    +  +N L   P +S++     +  SSS
Sbjct: 3399 TPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSS 3439



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 11/126 (8%)

Query: 403  TTTRVSTASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDE 462
            T+  +ST SEG+++ + + +S+  +AS E ++   +P +      T S    S T+    
Sbjct: 1502 TSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTT---A 1558

Query: 463  DKTAKLHHSFASRG-------PVSSDVEENDSLNLLGILPNNSDSAKKNISHISSSHWGE 515
            D T+ +  S  S G       PVS+ +  +   N L   P +S +     +  SSS   E
Sbjct: 1559 DGTS-MQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAE 1617

Query: 516  FSTQNV 521
             S+  +
Sbjct: 1618 GSSMTI 1623



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 63/281 (22%), Positives = 109/281 (38%), Gaps = 46/281 (16%)

Query: 251  LLATPPSIVSPITCLSEAEEVCNLSGADAVPTLSENSPS-GQRDVSLDKRSDGIFTNTVT 309
            L ATP    +P+T  +EA      +   ++PT   ++PS G   ++    S  +  N+  
Sbjct: 944  LSATPVDTSTPVTTSTEATSSPTTAEGTSIPT---STPSEGTTPLTSTPVSHTLVANSEA 1000

Query: 310  ENLLETPLEKQS-------------AAEGLKTLTILPACWSSKEEFISPDLRVSKSDSTF 356
              L  TP++  +              AEG    T +P   S+  E  +P  R+  S +T 
Sbjct: 1001 STLSTTPVDSNTPLTTSTEASSPPPTAEG----TSMPT--STPSEGSTPLTRMPVS-TTM 1053

Query: 357  HNQASVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTTTRVSTASEGASS 416
               +   TL  +P+    D    +     Y + + SS   D     T+   ST SEG++ 
Sbjct: 1054 VASSETSTLSTTPA----DTSTPVT---TYSQASSSSTTADG----TSMPTSTYSEGSTP 1102

Query: 417  FSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASRG 476
             + + +S+  + S E S    +P+       T +    S T+ +       +  S  S G
Sbjct: 1103 LTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEG----TSIPTSPPSEG 1158

Query: 477  -------PVSSDVEENDSLNLLGILPNNSDSAKKNISHISS 510
                   PVS+ +  +   N L   P +S +     +  SS
Sbjct: 1159 TTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASS 1199



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 43/210 (20%), Positives = 89/210 (42%), Gaps = 15/210 (7%)

Query: 401  LKTTTRVSTASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTL-SHQQLSSTSF 459
            + T+T V+T++E  SS  P +     + +   S  + +P+ + P   TL ++ + S+ S 
Sbjct: 1774 IDTSTPVTTSTEATSS--PTTAEGTSIPTSTLSEGM-TPLTSTPVSHTLVANSEASTLST 1830

Query: 460  KDEDKTAKLHHSFASRGPVSSDVEENDSLNLLGILPNNSDSAKKNI----SHISSSHWGE 515
               D  + +  S A    VSS     +  ++    P+   +A  +I    + ++SS    
Sbjct: 1831 TPVDSNSPVVTSTA----VSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNT 1886

Query: 516  FSTQNVDQFIPLSCSGFQSTKDFPQEPEAKNSISVLLREVKRAIARLHEDLSTVIQ-ELN 574
             ST       P++   +      P   +  +  +   RE +  +  +    +TV   E+N
Sbjct: 1887 LSTTPAVTSTPVTT--YAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEIN 1944

Query: 575  VINNILMSMSLNSSQISQSSQVPQSSEGSS 604
             ++  L       +  SQ+S  P +++G+S
Sbjct: 1945 TLSTTLADTRTPVTTYSQASSSPTTADGTS 1974



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 58/302 (19%), Positives = 101/302 (33%), Gaps = 59/302 (19%)

Query: 217 TETMLSQETLPLKIHGWKSTEDLMTFLDDDPELPLLATPPSIVSPITCLSEAEEVCNLSG 276
           T T+++  T P  +        ++T    +   PL   P S +   +  +       +  
Sbjct: 361 TSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDS 420

Query: 277 ADAVPTLSENSPSGQRDVSLDKRSDGIFTNTVTENLLETPLEKQSAAEGLKTLTILPACW 336
              V T SE S S                 T  E   +T +   + +EG   LT +P   
Sbjct: 421 KTFVTTASEASSSP----------------TTAE---DTSIATSTPSEGSTPLTSMPVST 461

Query: 337 SSKEEFISPDLRVSKSDSTFHNQASVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQM 396
           +      + +L  +  DS      S E     P+ ++                       
Sbjct: 462 TPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEV----------------------- 498

Query: 397 DDKILKTTTRVSTASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSS 456
                  +   ST SEG++  + +S+S+  +AS E S    +P+       T S    SS
Sbjct: 499 ------NSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSS 552

Query: 457 TSFKDEDKTAKLHHSFASRG-------PVSSDVEENDSLNLLGILPNNSDSAKKNISHIS 509
           T+     +   +  S  S G       PVS+ +  +   +     P +S++     S  S
Sbjct: 553 TT----PEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEAS 608

Query: 510 SS 511
           SS
Sbjct: 609 SS 610



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 46/205 (22%), Positives = 83/205 (40%), Gaps = 38/205 (18%)

Query: 403  TTTRVSTASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDE 462
            T+ R+ST S+G++  + + +S+  +AS E S    + +         S    +ST     
Sbjct: 2739 TSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAV-------DTSIPVTTSTEASSS 2791

Query: 463  DKTAKLHHSFASRGPVSSDVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVD 522
              TA++     +  P S+  E +  L  + +          N + ++SS  G  ST  VD
Sbjct: 2792 PTTAEV-----TSMPTSTPSETSTPLTSMPV----------NHTPVASSEAGTLSTTPVD 2836

Query: 523  QFIPLSCSGFQSTKDFPQEPEAKNSISVLLREVKRAIARLHEDLSTVIQELNVINNILMS 582
               P++ S   S+      P     I V +              ST++  + V    + S
Sbjct: 2837 TSTPVTTSTKASS-----SPTTAEGIVVPISTASEG--------STLLTSIPVSTTPVAS 2883

Query: 583  ---MSLNSSQISQSSQVPQSSEGSS 604
                +L+++ +  S  V  S+EGSS
Sbjct: 2884 SEASTLSTTPVDTSIPVTTSTEGSS 2908



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 75/368 (20%), Positives = 136/368 (36%), Gaps = 58/368 (15%)

Query: 254  TPPSIVSPITCLSEAEEVCNLSGADAVPTLSENSPSGQRDVSLDKRSDGIFTNTVTEN-- 311
            TP    +P+T  +EA      +   ++PT    SP  +    L   S  + T  V  +  
Sbjct: 2420 TPVDTSTPVTTSTEASSSPTTAEGTSIPT----SPPSEGTTPL--ASMPVSTTPVVSSEA 2473

Query: 312  --LLETPLEKQSAAEGLKTLTILPACWSSKEEFISPDLRVSKSDSTFHNQASVETLCLSP 369
              L  TP++  +    + T T   +  ++ E+ + P    S+  +   +     T   SP
Sbjct: 2474 GTLSTTPVDTSTP---MTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASP 2530

Query: 370  SFKIF-----DRVKEIVINKAYQKPAQSSIQMDDKILKTTTRVSTASEGASSFSPLSMSS 424
                      D    +V +      A S+         T+   ST SEG++    + +S+
Sbjct: 2531 EASTLSTTPVDSNSPVVTSTEISSSATSAEG-------TSMPTSTYSEGSTPLRSMPVST 2583

Query: 425  PDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASRGPVSSDVEE 484
              LAS E S    +P+       T +    S T+ KD               P+S+  E 
Sbjct: 2584 KPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSM------------PISTPSEV 2631

Query: 485  NDSLN--LLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQFIPLSCSGFQSTKDFPQEP 542
            + SL   L+  +P            ++SS     ST  VD    ++ S    T   P   
Sbjct: 2632 STSLTSILVSTMP------------VASSEASTLSTTPVDTRTLVTTS--TGTSSSPTTA 2677

Query: 543  EAKNSISVLLREVKRAIARLHEDLSTVI---QELNVINNILMSMSLNSSQISQSSQVPQS 599
            E  +  +    E    +  +   +ST +    E + ++   +  S   +  +++S  P +
Sbjct: 2678 EGSSMPTSTPGERSTPLTNIL--VSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTT 2735

Query: 600  SEGSSDQI 607
            +EG+S +I
Sbjct: 2736 AEGTSMRI 2743



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 3/112 (2%)

Query: 403  TTTRVSTASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDE 462
            T+   ST SEG++  S + +S+  +AS E S    +P+       T S    S T+ +  
Sbjct: 3446 TSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVT 3505

Query: 463  D---KTAKLHHSFASRGPVSSDVEENDSLNLLGILPNNSDSAKKNISHISSS 511
                 TA    +  +  PVS+    +   + L   P +S++   + S  SSS
Sbjct: 3506 SMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSS 3557



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 63/293 (21%), Positives = 107/293 (36%), Gaps = 34/293 (11%)

Query: 215  LPTETMLSQETLPLKIHGWKSTEDLMTFLDDDPELPL-LATPPSIVSPITCLSEAEEVCN 273
            LPT T  S+ + PL I    +T    +        P+  +TP +  SP        EV +
Sbjct: 3448 LPTSTT-SEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTS 3506

Query: 274  L--SGADAVPTLSENSPSGQRDVSLDKRSDGIFTNTVTENLLETPLEKQSAAEGLKTLTI 331
            +  S A    T   N P     V+  + S  + T  V  N   T   + S++     +T 
Sbjct: 3507 MPTSTAGEGSTPLTNMPVSTTPVASSEAST-LSTTPVDSNTFVTSSSQASSSPATLQVTT 3565

Query: 332  LPACWSSKEEFISPDLRVSKSDSTFHNQASVETLCLSPSFKIFDRVKEI----------- 380
            +     S+    S  L      ST+   +   T    PS    DR   +           
Sbjct: 3566 MRMSTPSEG---SSSLTTMLLSSTYVTSSEAST----PSTPSVDRSTPVTTSTQSNSTPT 3618

Query: 381  ---VINKAYQKPAQSSIQMDDKILKTTTRVSTASEGASSFSPLSMSSPDLASPEKSAHLL 437
               VI      P++ S  +    + TT+ V+ +  G +S  P+  S+P + S + S+  +
Sbjct: 3619 PPEVITLPMSTPSEVSTPLTIMPVSTTS-VTISEAGTASTLPVDTSTPVITSTQVSSSPV 3677

Query: 438  SPILAGPSFWT-------LSHQQLSSTSFKDEDKTAKLHHSFASRGPVSSDVE 483
            +P       WT       L+   +S+T     + +     S  +  PV++  E
Sbjct: 3678 TPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTE 3730



 Score = 29.6 bits (65), Expect = 8.4
 Identities = 25/111 (22%), Positives = 53/111 (47%), Gaps = 9/111 (8%)

Query: 407  VSTASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTA 466
            +S  SEG+   + + +S+  +ASPE S    +P+ +      ++  ++SS+    E  T+
Sbjct: 2094 ISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSP--VITSTEVSSSPIPTEG-TS 2150

Query: 467  KLHHSFASRG------PVSSDVEENDSLNLLGILPNNSDSAKKNISHISSS 511
                +++ R       PVS+ V  + +++ L   P ++ +   N +   SS
Sbjct: 2151 MQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSS 2201


>gi|42718017 retinoblastoma binding protein 8 isoform b [Homo
           sapiens]
          Length = 867

 Score = 35.0 bits (79), Expect = 0.20
 Identities = 47/171 (27%), Positives = 77/171 (45%), Gaps = 26/171 (15%)

Query: 391 QSSIQMDDKILKTT------TRVSTASEGASSF--SPLSMS---SPDLASPEKSAHLLSP 439
           + S++  D   KT       TRVS+   GA+S   S L ++   SP L  P K  HL + 
Sbjct: 303 EDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLKTL 362

Query: 440 ILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASRGPVSSDVEENDSLNLLGILPNNSD 499
                 F      +L  T  K ED     HHS  S   V+  + ++ +  +L I  N S+
Sbjct: 363 -----PFSNTCISRLEKTRSKSEDSALFTHHSLGSE--VNKIIIQSSNKQIL-INKNISE 414

Query: 500 SAKKNISHISSSHWGEFSTQNVDQFI-PLSCSGFQSTKDFPQEPEAKNSIS 549
           S    +   + + +G+ S  N D+ + PL   G +++K    E E+++ +S
Sbjct: 415 S----LGEQNRTEYGKDS--NTDKHLEPLKSLGGRTSKRKKTEEESEHEVS 459


>gi|42718015 retinoblastoma binding protein 8 isoform a [Homo
           sapiens]
          Length = 897

 Score = 35.0 bits (79), Expect = 0.20
 Identities = 47/171 (27%), Positives = 77/171 (45%), Gaps = 26/171 (15%)

Query: 391 QSSIQMDDKILKTT------TRVSTASEGASSF--SPLSMS---SPDLASPEKSAHLLSP 439
           + S++  D   KT       TRVS+   GA+S   S L ++   SP L  P K  HL + 
Sbjct: 303 EDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLKTL 362

Query: 440 ILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASRGPVSSDVEENDSLNLLGILPNNSD 499
                 F      +L  T  K ED     HHS  S   V+  + ++ +  +L I  N S+
Sbjct: 363 -----PFSNTCISRLEKTRSKSEDSALFTHHSLGSE--VNKIIIQSSNKQIL-INKNISE 414

Query: 500 SAKKNISHISSSHWGEFSTQNVDQFI-PLSCSGFQSTKDFPQEPEAKNSIS 549
           S    +   + + +G+ S  N D+ + PL   G +++K    E E+++ +S
Sbjct: 415 S----LGEQNRTEYGKDS--NTDKHLEPLKSLGGRTSKRKKTEEESEHEVS 459


>gi|4506441 retinoblastoma binding protein 8 isoform a [Homo
           sapiens]
          Length = 897

 Score = 35.0 bits (79), Expect = 0.20
 Identities = 47/171 (27%), Positives = 77/171 (45%), Gaps = 26/171 (15%)

Query: 391 QSSIQMDDKILKTT------TRVSTASEGASSF--SPLSMS---SPDLASPEKSAHLLSP 439
           + S++  D   KT       TRVS+   GA+S   S L ++   SP L  P K  HL + 
Sbjct: 303 EDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLKTL 362

Query: 440 ILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASRGPVSSDVEENDSLNLLGILPNNSD 499
                 F      +L  T  K ED     HHS  S   V+  + ++ +  +L I  N S+
Sbjct: 363 -----PFSNTCISRLEKTRSKSEDSALFTHHSLGSE--VNKIIIQSSNKQIL-INKNISE 414

Query: 500 SAKKNISHISSSHWGEFSTQNVDQFI-PLSCSGFQSTKDFPQEPEAKNSIS 549
           S    +   + + +G+ S  N D+ + PL   G +++K    E E+++ +S
Sbjct: 415 S----LGEQNRTEYGKDS--NTDKHLEPLKSLGGRTSKRKKTEEESEHEVS 459


>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
          Length = 861

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 57/253 (22%), Positives = 97/253 (38%), Gaps = 44/253 (17%)

Query: 304 FTNTVTENLLETPLEKQSAAEGLKTLTILPACWSSKEEFI-SPDLRVSKSDSTFHNQASV 362
           F+N     L   P+  +  +  + T  +L     S   F+ SPD     S +T     + 
Sbjct: 535 FSNPSAVYLPSAPISSRLTSSYIMTSAML-----SNAAFVTSPDPSALMSHTTAFPHVAA 589

Query: 363 ETLCLSPSFKIFDRVKEI--VINKAYQKPAQSSIQMDDKILKTTTR-------------V 407
               +  +FK    V  I  VI     KP+++      K+   +TR              
Sbjct: 590 TLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQS 649

Query: 408 STASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAK 467
           ST+S  +SS S L  S   L+SP    H  + +L   S        L+S        +  
Sbjct: 650 STSSSSSSSSSSLQTS---LSSPLSGPHKKNCVLNASS-------ALNSYQAAPPYNSLS 699

Query: 468 LHHSFASRGPVSSDVEEN----------DSLNLLGILPNNSDSAKKNISHISSSHWGEFS 517
           +H+S     P+S+ +E +          D +  +G +  +SDS   ++  + + H G+ S
Sbjct: 700 VHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSL-ALHAGDLS 758

Query: 518 --TQNVDQFIPLS 528
             + N    +PLS
Sbjct: 759 LASHNAVSSLPLS 771


>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
          Length = 738

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 57/253 (22%), Positives = 97/253 (38%), Gaps = 44/253 (17%)

Query: 304 FTNTVTENLLETPLEKQSAAEGLKTLTILPACWSSKEEFI-SPDLRVSKSDSTFHNQASV 362
           F+N     L   P+  +  +  + T  +L     S   F+ SPD     S +T     + 
Sbjct: 411 FSNPSAVYLPSAPISSRLTSSYIMTSAML-----SNAAFVTSPDPSALMSHTTAFPHVAA 465

Query: 363 ETLCLSPSFKIFDRVKEI--VINKAYQKPAQSSIQMDDKILKTTTR-------------V 407
               +  +FK    V  I  VI     KP+++      K+   +TR              
Sbjct: 466 TLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQS 525

Query: 408 STASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAK 467
           ST+S  +SS S L  S   L+SP    H  + +L   S        L+S        +  
Sbjct: 526 STSSSSSSSSSSLQTS---LSSPLSGPHKKNCVLNASS-------ALNSYQAAPPYNSLS 575

Query: 468 LHHSFASRGPVSSDVEEN----------DSLNLLGILPNNSDSAKKNISHISSSHWGEFS 517
           +H+S     P+S+ +E +          D +  +G +  +SDS   ++  + + H G+ S
Sbjct: 576 VHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSL-ALHAGDLS 634

Query: 518 --TQNVDQFIPLS 528
             + N    +PLS
Sbjct: 635 LASHNAVSSLPLS 647


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 32.7 bits (73), Expect = 0.99
 Identities = 51/218 (23%), Positives = 80/218 (36%), Gaps = 32/218 (14%)

Query: 253 ATPPSIVSPITCLSEAEEVCNLSGADAVPTLSENSPSGQRDVSLDKR------------- 299
           +T P   + +T   +AE     + A      SE + SG R  S                 
Sbjct: 761 STSPDTAAAMTHTHQAES----TEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPS 816

Query: 300 -SDGIFTNTVTENLLETPLEKQSAAEGLKTLTILPACWSSKEEFISPDLRVSKSDSTFHN 358
            S+GI T+  T      P       +   T  +L A  S     +S  +  S    TFH 
Sbjct: 817 GSEGISTSGETTRFSSNPSRDSHTTQS--TTELLSASASHGAIPVSTGMASSIVPGTFHP 874

Query: 359 QASVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTTT---RVSTASEGAS 415
             S  +    P+     +      + + Q+ A  S     +  +T+     +S AS+   
Sbjct: 875 TLSEASTAGRPT----GQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATD 930

Query: 416 SFS-----PLSMSSPDLASPEKSAHLLSPILAGPSFWT 448
           +FS     P S++S  L SP+   H LSP  +G +F T
Sbjct: 931 TFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTT 968


>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
          Length = 2156

 Score = 32.7 bits (73), Expect = 0.99
 Identities = 29/129 (22%), Positives = 63/129 (48%), Gaps = 4/129 (3%)

Query: 479  SSDVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQFIPLSCSGFQSTKDF 538
            S D+EE  +    G + N+  S+++NIS + S  + E    + D F  +   G Q+T++ 
Sbjct: 1436 SFDMEEPRTSEEPGSITNSMTSSERNISELES--FEELENHDTDIFNTVVNGGEQATEEL 1493

Query: 539  PQEPEAKNSISVLLREVKRAIARLHEDLSTVIQELNVINNILMSMSLNSSQISQSSQVPQ 598
             QE E + S ++ L ++        + ++ +I E+ +   +    SL+    S+ +   +
Sbjct: 1494 IQE-EVEASKTLELIDISSKNIMEEKRMNGIIYEI-ISKRLATPPSLDFCYDSKQNSEKE 1551

Query: 599  SSEGSSDQI 607
            ++EG +  +
Sbjct: 1552 TNEGETKMV 1560


>gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Homo
           sapiens]
          Length = 3549

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 354 STFHNQASVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTTTR-VSTASE 412
           S FH     ET+  +P  +   +V   ++ + ++K AQ  I   DK + T  + + T SE
Sbjct: 338 SQFHQYVQ-ETVIDTPEDEEIPKVSTKLLKEQFEKSAQEKILYSDKEMTTPAKQIKTESE 396

Query: 413 GASSFSPLSMSSPDLAS 429
              +F P S+ S    S
Sbjct: 397 YEETFKPSSVVSTSSTS 413


>gi|169171850 PREDICTED: similar to intestinal mucin MUC3B [Homo
           sapiens]
          Length = 385

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 50/242 (20%)

Query: 215 LPTETMLSQETLPLKIHGWKSTEDLMTFLDDDPELPLLATPPSIVSPITCLSEAEEVCNL 274
           L T T  S  T P         E   T L + P    LA  P  V  +            
Sbjct: 23  LSTATSTSHVTFP-------RAEATRTALSNSPHSRYLAEWPQGVPQL------------ 63

Query: 275 SGADAVPTLSENSPSGQRDVSLDKR-SDGIFTNTVTENLLETPLEK-----QSAAEGLKT 328
             A   P   EN+P        D   S+ + ++ V+ N   TP  K      +  +G   
Sbjct: 64  --ASPAPGHRENAPMTLTTSPHDTLISETLLSSLVSSNTSTTPTSKFXXXXXTTEKGTSA 121

Query: 329 LTILPACWSSKEE---FISPDLRVSKSDSTFHNQASVET--------------LCLSPSF 371
           +   P+  +++E     ++P   VS +D+TFH   S  T                +SP+ 
Sbjct: 122 MISSPSTTTARETPIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTMSPT- 180

Query: 372 KIFDRVKEIVINKAYQKPAQSSIQMDDKI--LKTTTRVSTASEGASSFSPLSMSSPDLAS 429
            +F  +K  V + +   P  S+I   + +  + TTT   TA+   SS +   +SS    +
Sbjct: 181 PVFTTLKTAVTSTS---PITSTITSTNTVTSMTTTTSRPTATNTLSSLTSSILSSTPAPN 237

Query: 430 PE 431
            E
Sbjct: 238 TE 239


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 39/137 (28%), Positives = 58/137 (42%), Gaps = 15/137 (10%)

Query: 344  SPDLRVSKSDSTFHNQASVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKT 403
            +P + V+ S  T    +S  T   S SF        +  N + + P+         +   
Sbjct: 2061 APPMTVTTS-GTSQTHSSFSTATASSSF--ISSSSWLPQNSSSRPPSSPITTQLPHLSSA 2117

Query: 404  TTRVSTASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDED 463
            TT VST ++ +SSFSP S S+P   S    +   SP  + PS  T       S+SF    
Sbjct: 2118 TTPVSTTNQLSSSFSP-SPSAPSTVSSYVPSSHSSPQTSSPSVGT-------SSSF---- 2165

Query: 464  KTAKLHHSFASRGPVSS 480
             +A +H +  S G  SS
Sbjct: 2166 VSAPVHSTTLSSGSHSS 2182


>gi|4758696 mitogen-activated protein kinase kinase kinase 13 [Homo
           sapiens]
          Length = 966

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 40/170 (23%), Positives = 70/170 (41%), Gaps = 6/170 (3%)

Query: 161 QLGSSNSLTACTSAPTPDISASEKKYKLPKFGRLHNKRNVCK-AGLKQEHCQDV-HLPTE 218
           Q GS +  +A     +PD+S S     L +  +   K    + +G + E      HL T 
Sbjct: 739 QYGSLDIPSAEPVGRSPDLSKSPAHNPLLENAQSSEKTEENEFSGCRSESSLGTSHLGTP 798

Query: 219 TMLSQETLPLKIHGWKSTEDLMTFLDDDPELPLLATPPSIVSPITCLS--EAEEVCNLSG 276
             L ++T PL+  G  S+E+    +D + E P    P   +S     S   +E      G
Sbjct: 799 PALPRKTRPLQKSGDDSSEEEEGEVDSEVEFPRRQRPHRCISSCQSYSTFSSENFSVSDG 858

Query: 277 ADAVPTLSENSPSGQRDVSLDKRSDGIFTNTVTENLLETPLEKQSAAEGL 326
            +   +   NSP    D   D+ ++ +  + +     E P++  S ++GL
Sbjct: 859 EEGNTSDHSNSPDELADKLEDRLAEKL--DDLLSQTPEIPIDISSHSDGL 906


>gi|50811889 centrosomal protein 192kDa [Homo sapiens]
          Length = 1941

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 29/123 (23%), Positives = 50/123 (40%), Gaps = 17/123 (13%)

Query: 246 DPELPLLATPPSIVSPITCLSEAEEVCNLSGADAV-------------PTLSENSPSGQR 292
           + EL  L   P+ VS +T +SE E     +  D                T+ + SP+   
Sbjct: 428 EQELSPLVCSPAGVSRLTYVSEPESSYPTTATDDALEDRKSDITSELSTTIIQGSPAALE 487

Query: 293 DVSLDKRSDGIFTNTVTENLLETPLEKQSAAEGLKTLTILPACWSSKEEFISPDLRVSKS 352
           + +++K  + +      +  L + ++  S        T L    SSK E++ PD R SK 
Sbjct: 488 ERAMEKLREKVPFQNRGKGTLSSIIQNNSDTRKATETTSL----SSKPEYVKPDFRWSKD 543

Query: 353 DST 355
            S+
Sbjct: 544 PSS 546


>gi|22325364 ubiquitin associated protein 2 [Homo sapiens]
          Length = 1119

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 50/263 (19%), Positives = 102/263 (38%), Gaps = 24/263 (9%)

Query: 356 FHNQASVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTT------TRVST 409
           F ++ S+     +PS +  +++   + +K+  +P  +S+ M   +  +T      T  S 
Sbjct: 541 FGSEPSLSEFGSAPSSENSNQIPISLYSKSLSEPLNTSLSMTSAVQNSTYTTSVITSCSL 600

Query: 410 ASEGASSFSPLSMSSP-DLASPEKSAHLLSPIL---AGPSFWTLSHQQLSSTSFKDEDKT 465
            S   +S SP++MSS  D +S        SP+    + P      H    S    D  KT
Sbjct: 601 TSSSLNSASPVAMSSSYDQSSVHNRIPYQSPVSSSESAPGTIMNGHGGGRSQQTLDTPKT 660

Query: 466 AKLHHSFASRGPVSSDVEENDSLNLLGILPNNS----DSAKKNISHISSSHWGEFSTQNV 521
                +  S   + S      + +   +LP+ S    D     +S +SSS     S+ + 
Sbjct: 661 TGPPSALPSVSSLPS------TTSCTALLPSTSQHTGDLTSSPLSQLSSSLSSHQSSLSA 714

Query: 522 DQFIPLSCSGFQSTKDFPQEPEAKNSISVLLREVKRAIARLHEDLSTVIQELNVINNILM 581
              +  S S   ++ +     ++  + S     V  + +      +++   +N  N++ +
Sbjct: 715 HAALSSSTSHTHASVESASSHQSSATFSTAATSVSSSAS----SGASLSSSMNTANSLCL 770

Query: 582 SMSLNSSQISQSSQVPQSSEGSS 604
             +  S+  S S   P  + G +
Sbjct: 771 GGTPASASSSSSRAAPLVTSGKA 793


>gi|39930471 hypothetical protein LOC84190 [Homo sapiens]
          Length = 603

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 17/48 (35%), Positives = 26/48 (54%)

Query: 1   MAFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTI 48
           MA  R+VKN VKN +D E     + +N    P+S+++ D S    + I
Sbjct: 242 MAKERKVKNKVKNKADTEEVFNNSPTNQEKMPTSAILPDFSGSVISNI 289


>gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 5/61 (8%)

Query: 424 SPDLASPEKSAHLLSPILAGPSFW---TLSHQQLSSTSFKDEDKTAKLHHSFASRGPVSS 480
           SPDL + +KS H  S   + P  W    +S  Q  S   K   K   LH S AS  P SS
Sbjct: 798 SPDLLTLQKSIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKL--LHLSSASNHPASS 855

Query: 481 D 481
           D
Sbjct: 856 D 856


>gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 5/61 (8%)

Query: 424 SPDLASPEKSAHLLSPILAGPSFW---TLSHQQLSSTSFKDEDKTAKLHHSFASRGPVSS 480
           SPDL + +KS H  S   + P  W    +S  Q  S   K   K   LH S AS  P SS
Sbjct: 798 SPDLLTLQKSIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKL--LHLSSASNHPASS 855

Query: 481 D 481
           D
Sbjct: 856 D 856


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 30.4 bits (67), Expect = 4.9
 Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 24/106 (22%)

Query: 247 PELPLLATPPSIVSPITCLSEAEEVCNLSGADAVPTLSENSPSGQRDVSLDKRSDGIFTN 306
           P+LPL A PPS V P+   SEA            P    ++P+ +R +        +F  
Sbjct: 321 PQLPLNAAPPSSVPPVP-PSEA----------LPPPACPSAPAPRRSI-----ISRLFGT 364

Query: 307 TVTENLLETPLEKQSAAEGLKTLTILPACWSSKEEFISPDLRVSKS 352
           +        P E   AAEG       PA   S E+F+ PD R+ +S
Sbjct: 365 SPATEAAPPPPEPVPAAEG-------PATVQSVEDFV-PDDRLDRS 402


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
           sapiens]
          Length = 907

 Score = 30.4 bits (67), Expect = 4.9
 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 7/108 (6%)

Query: 21  VREATSNDPWGPSSSLMLDISDLTFNT-ISLSEIMNMLWHRLNDHGKNWRHVYKSLTLMD 79
           V +AT+++  GP    +  +   T  T +++ ++ + L+ R  +   +W  V+K+L    
Sbjct: 26  VCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMADTLFERATN--SSWVVVFKALVTTH 83

Query: 80  YLIKNGSKKVIQH--CREGFCNLQTLKDFQHIDEAGKDQGYYIREKSK 125
           +L+ +G+++ IQ+   R    NL    D       G D   +IR  S+
Sbjct: 84  HLMVHGNERFIQYLASRNTLFNLSNFLD--KSGSHGYDMSTFIRRYSR 129


>gi|46240864 sperm associated antigen 17 [Homo sapiens]
          Length = 2223

 Score = 30.4 bits (67), Expect = 4.9
 Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 19/161 (11%)

Query: 66   KNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQT--LKDF--QHIDEAGKDQGYYIR 121
            K WRH   S    + + K  ++K I+  +    +++   +  F    +++  + Q  ++ 
Sbjct: 1871 KTWRHTASSKRWKEKIDK--TRKEIETTQNYLMDIKNRIIPPFFKSELNQLYQSQYNHLD 1928

Query: 122  EKSKQVITLLMDEPLLCKEREVACRTR-QRTSHSILFSKRQLGSSNSLTACTSAPTPDIS 180
              SK++       P   K+ E A  T  Q TS   L  K    S    ++  S P P+IS
Sbjct: 1929 SLSKKL-------PSFTKKNEDANETAVQDTSDLNLDFKPHKVSEQKSSSVPSLPKPEIS 1981

Query: 181  ASEKKYKLPKFGRLHNKRNVCKAGLKQEHCQDVHLPTETML 221
            A +K      F   +   N+ K+  + E  + V +PT+++L
Sbjct: 1982 ADKK-----DFTAQNQTENLTKSPEEAESYEPVKIPTQSLL 2017


>gi|58743369 hypothetical protein LOC139231 [Homo sapiens]
          Length = 388

 Score = 30.4 bits (67), Expect = 4.9
 Identities = 41/161 (25%), Positives = 70/161 (43%), Gaps = 26/161 (16%)

Query: 275 SGADAVPTLSENSPSG--------QRDVSLDKRSDGIFTNTVTENLLETPLEKQSAAEGL 326
           SG+D +  +  + PS          +  +LD+      TN      +E    K S   GL
Sbjct: 147 SGSDVLSDVIPSIPSSPCLLPKKKNKHRNLDELPWSAMTNDEQVEYIEYLSRKVSTEMGL 206

Query: 327 KT-LTILPACWSSKEEFISPDLRVSKSDSTFHNQASVETLCLSPSF--KIFDRVKEIVIN 383
           +  L I+        + I P  ++S +DS F     +E  CL+     ++ + +KE   +
Sbjct: 207 REQLDII--------KIIDPSAQISPTDSEF----IIELNCLTDEKLKQVRNYIKE---H 251

Query: 384 KAYQKPAQSSIQMDDKILKTTTRVSTASEGASSFSPLSMSS 424
              Q+PA+ + +  +    +T+ VS AS  ASS S   +SS
Sbjct: 252 SPRQRPAREAWKRSNFSCASTSGVSGASASASSSSASMVSS 292


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.127    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,605,265
Number of Sequences: 37866
Number of extensions: 1020851
Number of successful extensions: 2636
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 2549
Number of HSP's gapped (non-prelim): 108
length of query: 607
length of database: 18,247,518
effective HSP length: 108
effective length of query: 499
effective length of database: 14,157,990
effective search space: 7064837010
effective search space used: 7064837010
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.