BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31077092 neurogenin 2 [Homo sapiens] (272 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31077092 neurogenin 2 [Homo sapiens] 546 e-156 gi|38455396 neurogenin 1 [Homo sapiens] 130 1e-30 gi|68989258 neurogenin 3 [Homo sapiens] 127 8e-30 gi|98986461 neurogenic differentiation 2 [Homo sapiens] 86 3e-17 gi|121114306 neurogenic differentiation 1 [Homo sapiens] 86 3e-17 gi|27475985 neurogenic differentiation 6 [Homo sapiens] 82 7e-16 gi|153792190 neurogenic differentiation 4 [Homo sapiens] 80 2e-15 gi|4885075 atonal homolog 1 [Homo sapiens] 79 6e-15 gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens] 72 4e-13 gi|30039710 pancreas specific transcription factor, 1a [Homo sap... 72 7e-13 gi|4507741 twist [Homo sapiens] 71 1e-12 gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi... 71 1e-12 gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo... 67 2e-11 gi|116805332 musculin [Homo sapiens] 65 8e-11 gi|21553337 atonal homolog 7 [Homo sapiens] 64 1e-10 gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens] 63 2e-10 gi|48255909 basic helix-loop-helix transcription factor 15 [Homo... 63 2e-10 gi|148922889 scleraxis homolog B [Homo sapiens] 63 3e-10 gi|186972126 scleraxis homolog A [Homo sapiens] 63 3e-10 gi|22748877 basic helix-loop-helix domain containing, class B, 5... 63 3e-10 gi|226498192 atonal homolog 8 [Homo sapiens] 62 4e-10 gi|57529222 basic helix-loop-helix domain containing, class B, 4... 60 2e-09 gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens] 60 3e-09 gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi... 60 3e-09 gi|17981708 twist homolog 2 [Homo sapiens] 59 3e-09 gi|23097242 nephew of atonal 3 [Homo sapiens] 58 8e-09 gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens] 55 5e-08 gi|12545384 basic helix-loop-helix transcription factor HAND2 [H... 55 9e-08 gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens] 55 9e-08 gi|5031943 nescient helix loop helix 1 [Homo sapiens] 55 9e-08 >gi|31077092 neurogenin 2 [Homo sapiens] Length = 272 Score = 546 bits (1408), Expect = e-156 Identities = 272/272 (100%), Positives = 272/272 (100%) Query: 1 MFVKSETLELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAG 60 MFVKSETLELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAG Sbjct: 1 MFVKSETLELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAG 60 Query: 61 QGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNR 120 QGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNR Sbjct: 61 QGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNR 120 Query: 121 ERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGG 180 ERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGG Sbjct: 121 ERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGG 180 Query: 181 LPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSP 240 LPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSP Sbjct: 181 LPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSP 240 Query: 241 ASPAGSDMDYWQPPPPDKHRYAPHLPIARDCI 272 ASPAGSDMDYWQPPPPDKHRYAPHLPIARDCI Sbjct: 241 ASPAGSDMDYWQPPPPDKHRYAPHLPIARDCI 272 >gi|38455396 neurogenin 1 [Homo sapiens] Length = 237 Score = 130 bits (327), Expect = 1e-30 Identities = 88/206 (42%), Positives = 113/206 (54%), Gaps = 23/206 (11%) Query: 51 ARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIK 110 AR Q+ A A G GA A + D ++ R R +R ++ + ++ Sbjct: 33 ARLQQAASAS-GPPAPARRGAPNISRASEVPGAQDDEQERRRRRGRTR-VRSEALLHSLR 90 Query: 111 KTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRL 170 ++RR+KAN+RERNRMHNLNAALDALR VLP+FP+D KLTKIETLRFA+NYIWAL ETLRL Sbjct: 91 RSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRL 150 Query: 171 ADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNS 230 AD GGG L + V PG PSPAS S A ++S S+ Sbjct: 151 ADQGLPGGGARERLLPPQCVPCLPG-----------PPSPASDAESWGSGAAAASPLSD- 198 Query: 231 TSPYSCTLSPASPAGSDMDYWQPPPP 256 P+SPA S+ ++P P Sbjct: 199 ---------PSSPAASEDFTYRPGDP 215 >gi|68989258 neurogenin 3 [Homo sapiens] Length = 214 Score = 127 bits (320), Expect = 8e-30 Identities = 92/200 (46%), Positives = 109/200 (54%), Gaps = 46/200 (23%) Query: 64 RGGVAAGAEG-CRPARLLGLVHDCKRRPSRARAVSRGAKTAE-TVQRIKKTRRLKANNRE 121 RG A EG CR A R RAR R +E + + +++RR KAN+RE Sbjct: 43 RGNCAEAEEGGCRGAP----------RKLRARRGGRSRPKSELALSKQRRSRRKKANDRE 92 Query: 122 RNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLAD--------- 172 RNRMHNLN+ALDALR VLPTFP+DAKLTKIETLRFAHNYIWALT+TLR+AD Sbjct: 93 RNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSLYALEPP 152 Query: 173 --HCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNS 230 HCG G SPGG S GD S S S S +P++S+ Sbjct: 153 APHCGELG--------------SPGG------SPGDWGSLYSPVSQAGSLSPAASLEERP 192 Query: 231 ---TSPYSCTLSPASPAGSD 247 + +S LSP S A SD Sbjct: 193 GLLGATFSACLSPGSLAFSD 212 >gi|98986461 neurogenic differentiation 2 [Homo sapiens] Length = 382 Score = 86.3 bits (212), Expect = 3e-17 Identities = 60/135 (44%), Positives = 73/135 (54%), Gaps = 12/135 (8%) Query: 45 PGASGGARR--------QRGAEA--GQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRAR 94 PGA G AR + G EA + G G E GL RP + R Sbjct: 46 PGAPGPARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKK-R 104 Query: 95 AVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETL 154 + T ++R K RR KAN RERNRMH+LNAALD LR+V+P + + KL+KIETL Sbjct: 105 GPKKRKMTKARLER-SKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETL 163 Query: 155 RFAHNYIWALTETLR 169 R A NYIWAL+E LR Sbjct: 164 RLAKNYIWALSEILR 178 >gi|121114306 neurogenic differentiation 1 [Homo sapiens] Length = 356 Score = 85.9 bits (211), Expect = 3e-17 Identities = 47/85 (55%), Positives = 59/85 (69%), Gaps = 2/85 (2%) Query: 85 DCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPE 144 D ++P R R + T ++R K RR+KAN RERNRMH LNAALD LR+V+P + + Sbjct: 76 DDDQKPKR-RGPKKKKMTKARLERFK-LRRMKANARERNRMHGLNAALDNLRKVVPCYSK 133 Query: 145 DAKLTKIETLRFAHNYIWALTETLR 169 KL+KIETLR A NYIWAL+E LR Sbjct: 134 TQKLSKIETLRLAKNYIWALSEILR 158 >gi|27475985 neurogenic differentiation 6 [Homo sapiens] Length = 337 Score = 81.6 bits (200), Expect = 7e-16 Identities = 43/79 (54%), Positives = 56/79 (70%), Gaps = 1/79 (1%) Query: 92 RARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKI 151 R R + + T ++R+K RR +AN RERNRMH LN ALD LR+V+P + + KL+KI Sbjct: 75 RRRGLRKKKTTKLRLERVK-FRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKI 133 Query: 152 ETLRFAHNYIWALTETLRL 170 ETLR A NYIWAL+E LR+ Sbjct: 134 ETLRLAKNYIWALSEILRI 152 >gi|153792190 neurogenic differentiation 4 [Homo sapiens] Length = 331 Score = 80.1 bits (196), Expect = 2e-15 Identities = 62/170 (36%), Positives = 82/170 (48%), Gaps = 46/170 (27%) Query: 9 ELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVA 68 E+KEEE G L++LT S +EEEEEE G ++RG + Sbjct: 30 EVKEEESRPGTYGM----LSSLTEEHDSIEEEEEEEE--DGEKPKRRGPK---------- 73 Query: 69 AGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNL 128 K++ ++AR ++R + RR+KAN RER RMH L Sbjct: 74 ------------------KKKMTKAR-----------LERFR-ARRVKANARERTRMHGL 103 Query: 129 NAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGG 178 N ALD LR V+P + + KL+KIETLR A NYIWAL+E L G G Sbjct: 104 NDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLETGQTPEGKG 153 >gi|4885075 atonal homolog 1 [Homo sapiens] Length = 354 Score = 78.6 bits (192), Expect = 6e-15 Identities = 77/214 (35%), Positives = 98/214 (45%), Gaps = 27/214 (12%) Query: 24 SPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLV 83 SP L A S A +E G RR G + + G V + C+ L G V Sbjct: 84 SPELGA-----SEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCK---LKGGV 135 Query: 84 HDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFP 143 + SR RA S ++ V ++K RRL AN RER RMH LN A D LR V+P+F Sbjct: 136 VVDELGCSRQRAPS-----SKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFN 190 Query: 144 EDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGGLPGA--------LFSEAVLLSPG 195 D KL+K ETL+ A YI AL+E L+ GG P A L + A Sbjct: 191 NDKKLSKYETLQMAQIYINALSELLQTPS--GGEQPPPPPASCKSDHHHLRTAASYEGGA 248 Query: 196 G---ASAALSSSGDSPSPASTWSC-TNSPAPSSS 225 G A+ A +SG S P SC T AP+S+ Sbjct: 249 GNATAAGAQQASGGSQRPTPPGSCRTRFSAPASA 282 >gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens] Length = 272 Score = 72.4 bits (176), Expect = 4e-13 Identities = 58/172 (33%), Positives = 73/172 (42%), Gaps = 35/172 (20%) Query: 114 RLKANNRERNRMHNLNAALDALREVLPTF--PEDAKLTKIETLRFAHNYIWALTETL--- 168 RLK N RER RMH+LN A+D LREV+P P KL+KI TL A NYI LT +L Sbjct: 85 RLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEM 144 Query: 169 -----------RLADHCG--GGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWS 215 A HCG G G P + + P A S + SP A++ Sbjct: 145 KRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHPVHPILGGALSSGNASSPLSAASLP 204 Query: 216 CTNSPAPSSSVSSNSTSPYSCTLSPASPAGSDMDYW-----------QPPPP 256 + P S+ ++P PA GS +W PPPP Sbjct: 205 AIGTIRPPHSLLKAPSTP------PALQLGSGFQHWAGLPCPCTICQMPPPP 250 >gi|30039710 pancreas specific transcription factor, 1a [Homo sapiens] Length = 328 Score = 71.6 bits (174), Expect = 7e-13 Identities = 78/264 (29%), Positives = 106/264 (40%), Gaps = 51/264 (19%) Query: 2 FVKSETLELKEEEDVLVLLGSASPALA-ALTPLSSSADEEEEEEPGASGGARRQRGAEAG 60 F+ + E + +LL A PA AL P SS E ++ G GG + GA G Sbjct: 52 FLSHQLHEYCYRDGACLLLQPAPPAAPLALAPPSSGGLGEPDD--GGGGGYCCETGAPPG 109 Query: 61 ---------QGARGGVAAGAEGCRP-ARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIK 110 AGA P ARL GL A A +R + + ++ Sbjct: 110 GFPYSPGSPPSCLAYPCAGAAVLSPGARLRGL-------SGAAAAAARRRRRVRSEAELQ 162 Query: 111 KTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRL 170 + R+ AN RER RM ++N A + LR +PT P + +L+K++TLR A YI L+E ++ Sbjct: 163 QLRQA-ANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQA 221 Query: 171 ADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNS 230 GGG G G PGG GDSP S + Sbjct: 222 DLPLRGGGAGGCG---------GPGGGGRL---GGDSP------------------GSQA 251 Query: 231 TSPYSCTLSPASPAGSDMDYWQPP 254 C SP+ SD DY PP Sbjct: 252 QKVIICHRGTRSPSPSDPDYGLPP 275 >gi|4507741 twist [Homo sapiens] Length = 202 Score = 70.9 bits (172), Expect = 1e-12 Identities = 60/168 (35%), Positives = 85/168 (50%), Gaps = 29/168 (17%) Query: 22 SASPALAALTPLSSSADEEEEEEP--GASGG-----ARRQRGAEAGQG--ARGGVAAGAE 72 S+SP A LS+S +E + ++P G GG +RR G AG G A GGV G E Sbjct: 6 SSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDE 65 Query: 73 GCRPARLLGLVHDCKRRPSRARA-----------VSRGAKTAETVQRIKKTRRLKANNRE 121 PA+ KR A S G + ++ + ++ T+R+ AN RE Sbjct: 66 PGSPAQ-------GKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQ-TQRVMANVRE 117 Query: 122 RNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLR 169 R R +LN A ALR+++PT P D KL+KI+TL+ A YI L + L+ Sbjct: 118 RQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 164 >gi|29126247 basic helix-loop-helix family, member a15 [Homo sapiens] Length = 189 Score = 70.9 bits (172), Expect = 1e-12 Identities = 52/131 (39%), Positives = 65/131 (49%), Gaps = 15/131 (11%) Query: 38 DEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVS 97 D E G G+ G E +G R A A AR G +RRP + Sbjct: 16 DTEATPGEGTPDGSLPNPGPEPAKGLRSRPARAA-----ARAPG--EGRRRRPGPS---G 65 Query: 98 RGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFA 157 G + ++QR RL++N RER RMH LN A ALREV+P D KL+KIETL A Sbjct: 66 PGGRRDSSIQR-----RLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLA 120 Query: 158 HNYIWALTETL 168 NYI +LT T+ Sbjct: 121 KNYIKSLTATI 131 >gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo sapiens] Length = 323 Score = 66.6 bits (161), Expect = 2e-11 Identities = 72/248 (29%), Positives = 104/248 (41%), Gaps = 26/248 (10%) Query: 12 EEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGA 71 E +D+ + S + +A T + S+ + P S RGA GA G G Sbjct: 16 EPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSA---ELRGAMGSAGAHPGDKLGG 72 Query: 72 EGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAA 131 G + + S A A S + + + RLK N+RER RMH+LN A Sbjct: 73 SGFKSSS-----SSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIA 127 Query: 132 LDALREVLPTF--PEDAKLTKIETLRFAHNYIWALTETL----RLADHCGGG--GGGLP- 182 +D LREV+P P KL+KI TL A NYI LT +L RL GG G P Sbjct: 128 MDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPS 187 Query: 183 --GALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSP 240 G L A L + AA + + P+ + P + ++ + + + +S Sbjct: 188 ACGGLAHSAPLPAATAHPAAAAHAAHHPA-------VHHPILPPAAAAAAAAAAAAAVSS 240 Query: 241 ASPAGSDM 248 AS GS + Sbjct: 241 ASLPGSGL 248 >gi|116805332 musculin [Homo sapiens] Length = 206 Score = 64.7 bits (156), Expect = 8e-11 Identities = 50/145 (34%), Positives = 71/145 (48%), Gaps = 33/145 (22%) Query: 34 SSSADEEE---EEE------PGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVH 84 +SSA+EE+ EEE G++ G +R+R AG G GG +AG G +P G Sbjct: 44 NSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGG-SAGGGGKKPLPAKGSAA 102 Query: 85 DCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPE 144 +CK+ ++R AN RER RM L+ A L+ LP P Sbjct: 103 ECKQ-----------------------SQRNAANARERARMRVLSKAFSRLKTSLPWVPP 139 Query: 145 DAKLTKIETLRFAHNYIWALTETLR 169 D KL+K++TLR A +YI L + L+ Sbjct: 140 DTKLSKLDTLRLASSYIAHLRQLLQ 164 >gi|21553337 atonal homolog 7 [Homo sapiens] Length = 152 Score = 64.3 bits (155), Expect = 1e-10 Identities = 38/77 (49%), Positives = 46/77 (59%), Gaps = 4/77 (5%) Query: 99 GAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAH 158 GA E+ R RRL AN RER RM LN A D LR V+P + +D KL+K ETL+ A Sbjct: 31 GAGRLESAAR----RRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMAL 86 Query: 159 NYIWALTETLRLADHCG 175 +YI ALT L A+ G Sbjct: 87 SYIMALTRILAEAERFG 103 >gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens] Length = 331 Score = 63.2 bits (152), Expect = 2e-10 Identities = 54/158 (34%), Positives = 71/158 (44%), Gaps = 25/158 (15%) Query: 87 KRRPSRARA-VSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPED 145 KRRPS ++ G T K RR+ N+RER R N+N A LR+++PT P D Sbjct: 168 KRRPSPYEMEITDGPHT-------KVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPD 220 Query: 146 AKLTKIETLRFAHNYIWALTETLRLADH---------------CGGGGGGLPGALFSEAV 190 KL+K E LR A YI L + L + GGGGGG G + + Sbjct: 221 KKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDL 280 Query: 191 LLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSS 228 L +++ SS D AS S T PAP + S Sbjct: 281 LQDVLSPNSSCGSSLD--GAASPDSYTEEPAPKHTARS 316 >gi|48255909 basic helix-loop-helix transcription factor 15 [Homo sapiens] Length = 199 Score = 63.2 bits (152), Expect = 2e-10 Identities = 60/187 (32%), Positives = 72/187 (38%), Gaps = 41/187 (21%) Query: 36 SADEEEEEEPGAS----GGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPS 91 S DEE E AS G A G G GG AG G Sbjct: 22 SEDEENRSESDASDQSFGCCEGPEAARRGPGPGGGRRAGGGG------------------ 63 Query: 92 RARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKI 151 GA V++ R AN RER+R ++N A ALR ++PT P D KL+KI Sbjct: 64 -------GAGPVVVVRQ-----RQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKI 111 Query: 152 ETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPA 211 ETLR A +YI L L L D G A S GA A + G P Sbjct: 112 ETLRLASSYIAHLANVLLLGDSADDGQPCFRAA-------GSAKGAVPAAADGGRQPRSI 164 Query: 212 STWSCTN 218 T+ +N Sbjct: 165 CTFCLSN 171 >gi|148922889 scleraxis homolog B [Homo sapiens] Length = 201 Score = 62.8 bits (151), Expect = 3e-10 Identities = 52/160 (32%), Positives = 65/160 (40%), Gaps = 43/160 (26%) Query: 34 SSSADEE----EEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRR 89 SS +DE+ G G RR G AG G GG R Sbjct: 32 SSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGG----------------------R 69 Query: 90 PSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLT 149 P R + +R AN RER+R +++N A ALR ++PT P D KL+ Sbjct: 70 PGR-----------------EPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLS 112 Query: 150 KIETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFSEA 189 KIETLR A +YI L L + CG G G F A Sbjct: 113 KIETLRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHA 152 >gi|186972126 scleraxis homolog A [Homo sapiens] Length = 201 Score = 62.8 bits (151), Expect = 3e-10 Identities = 52/160 (32%), Positives = 65/160 (40%), Gaps = 43/160 (26%) Query: 34 SSSADEE----EEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRR 89 SS +DE+ G G RR G AG G GG R Sbjct: 32 SSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGG----------------------R 69 Query: 90 PSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLT 149 P R + +R AN RER+R +++N A ALR ++PT P D KL+ Sbjct: 70 PGR-----------------EPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLS 112 Query: 150 KIETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFSEA 189 KIETLR A +YI L L + CG G G F A Sbjct: 113 KIETLRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHA 152 >gi|22748877 basic helix-loop-helix domain containing, class B, 5 [Homo sapiens] Length = 381 Score = 62.8 bits (151), Expect = 3e-10 Identities = 66/209 (31%), Positives = 83/209 (39%), Gaps = 37/209 (17%) Query: 45 PGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAE 104 PG GG + G GG +G+ G S + + S K+ E Sbjct: 197 PGGLGGGGGGGSSSGSSGGGGGSGSGSGG-----------------SSSSSSSSSKKSKE 239 Query: 105 TVQRIKKTRRLKANNRERNRMHNLNAALDALREVLP--TFPEDAKLTKIETLRFAHNYI- 161 +K RL N RER RMH+LN ALD LR V+P P KL+KI TL A NYI Sbjct: 240 -----QKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYIL 294 Query: 162 ---WALTETLRLADHCGGG----GGGLPGALFSEAVLLSPGGASAALSSSGDSPSPAS-- 212 AL E RL + G LP + + A + A A + P A Sbjct: 295 MQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLP 354 Query: 213 -TWSCTNSPAPSSSVSSNSTSPYSCTLSP 240 SC A +SVSS+ CT P Sbjct: 355 PAASCPEKCALFNSVSSSLCK--QCTEKP 381 >gi|226498192 atonal homolog 8 [Homo sapiens] Length = 321 Score = 62.4 bits (150), Expect = 4e-10 Identities = 36/86 (41%), Positives = 53/86 (61%), Gaps = 9/86 (10%) Query: 87 KRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDA 146 ++RP A A S ++ +++TRRL AN RER R+H ++AA +ALR+ +P + Sbjct: 211 RKRPGEATAAS------SEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQ 264 Query: 147 KLTKIETLRFAHNYIWALTETLRLAD 172 KL+K+ LR A NYI +L RLAD Sbjct: 265 KLSKLAILRIACNYILSLA---RLAD 287 >gi|57529222 basic helix-loop-helix domain containing, class B, 4 [Homo sapiens] Length = 225 Score = 60.1 bits (144), Expect = 2e-09 Identities = 67/209 (32%), Positives = 83/209 (39%), Gaps = 56/209 (26%) Query: 23 ASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGL 82 A+PA A + S+ E+ +E A RR+RG G Sbjct: 51 AAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGP-----------------------GS 87 Query: 83 VHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLP-- 140 D +RRP R++ RL N RER RMH+LN ALD LR V+P Sbjct: 88 AADGRRRPREQRSL-----------------RLSINARERRRMHDLNDALDGLRAVIPYA 130 Query: 141 TFPEDAKLTKIETLRFAHNYI----WALTETLRLADHCGGGGG------GLPGALFSEAV 190 P KL+KI TL A NYI AL E RL G G P F +A Sbjct: 131 HSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQAT 190 Query: 191 LLSPGGASAALSSSGDSPSPASTWSCTNS 219 + P A AAL G P + +S T S Sbjct: 191 -VCPFSAGAAL---GPCPDKCAAFSGTPS 215 >gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens] Length = 193 Score = 59.7 bits (143), Expect = 3e-09 Identities = 56/168 (33%), Positives = 67/168 (39%), Gaps = 14/168 (8%) Query: 86 CKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPED 145 C RR A A + G A + N RERNR+ +N ALR+ +P Sbjct: 34 CSRRRRPATAETGGGAAAVA----------RRNERERNRVKLVNLGFQALRQHVPHGGAS 83 Query: 146 AKLTKIETLRFAHNYIWALTETLRLADHCGG--GGGGLPGALFSEAVLLSPGGASAALSS 203 KL+K+ETLR A YI AL L D GG P A+ A PG A S Sbjct: 84 KKLSKVETLRSAVEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASP 143 Query: 204 SGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSPASPAGSDMDYW 251 S S SP S + P S S+ S LSPA D W Sbjct: 144 SRASSSPGRGGS--SEPGSPRSAYSSDDSGCEGALSPAERELLDFSSW 189 >gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapiens] Length = 280 Score = 59.7 bits (143), Expect = 3e-09 Identities = 38/83 (45%), Positives = 44/83 (53%), Gaps = 5/83 (6%) Query: 87 KRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDA 146 KRRPS AE Q K RR+ N+RER R N+N A LR++LPT P D Sbjct: 130 KRRPSHCEL-----DLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDR 184 Query: 147 KLTKIETLRFAHNYIWALTETLR 169 KL+K E LR A YI L LR Sbjct: 185 KLSKNEVLRLAMKYIGFLVRLLR 207 >gi|17981708 twist homolog 2 [Homo sapiens] Length = 160 Score = 59.3 bits (142), Expect = 3e-09 Identities = 45/151 (29%), Positives = 77/151 (50%), Gaps = 34/151 (22%) Query: 21 GSASPALAALTPLSS--SADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPAR 78 GS+SP ++P+ S +++EE E +P G RR + G+ Sbjct: 4 GSSSP----VSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGS--------------- 44 Query: 79 LLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREV 138 P+ + +G+ +A++ + ++ ++R+ AN RER R +LN A ALR++ Sbjct: 45 -----------PTPGKRGKKGSPSAQSFEELQ-SQRILANVRERQRTQSLNEAFAALRKI 92 Query: 139 LPTFPEDAKLTKIETLRFAHNYIWALTETLR 169 +PT P D KL+KI+TL+ A YI L + L+ Sbjct: 93 IPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 122 >gi|23097242 nephew of atonal 3 [Homo sapiens] Length = 166 Score = 58.2 bits (139), Expect = 8e-09 Identities = 46/131 (35%), Positives = 57/131 (43%), Gaps = 34/131 (25%) Query: 38 DEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVS 97 D EEEE G + E G+G LLG RP R R ++ Sbjct: 61 DPEEEECEVDQGDGEEEEEEERGRGVS--------------LLG-------RPKRKRVIT 99 Query: 98 RGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFA 157 + A AN RER RM NLN A D LR +PTF + +L++IETLR A Sbjct: 100 YAQRQA-------------ANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLA 146 Query: 158 HNYIWALTETL 168 YI +TE L Sbjct: 147 IVYISFMTELL 157 >gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens] Length = 108 Score = 55.5 bits (132), Expect = 5e-08 Identities = 39/101 (38%), Positives = 51/101 (50%), Gaps = 3/101 (2%) Query: 112 TRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETL--R 169 TR++ N RER R N+N+A LR+++PT P D KL+K ETLR A YI L + L + Sbjct: 2 TRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQ 61 Query: 170 LADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSP 210 G G LF + L PG L + PSP Sbjct: 62 SLQQTGVAAQGNILGLFPQGPHL-PGLEDRTLLENYQVPSP 101 >gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo sapiens] Length = 217 Score = 54.7 bits (130), Expect = 9e-08 Identities = 29/63 (46%), Positives = 38/63 (60%) Query: 113 RRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLAD 172 RR AN +ER R ++N+A LRE +P P D KL+KI+TLR A +YI L + L D Sbjct: 100 RRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDD 159 Query: 173 HCG 175 G Sbjct: 160 QNG 162 >gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens] Length = 271 Score = 54.7 bits (130), Expect = 9e-08 Identities = 41/122 (33%), Positives = 57/122 (46%), Gaps = 9/122 (7%) Query: 99 GAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTF-------PEDAKLTKI 151 G+ + + ++ R K N+RER RM +LN A+DALREV+ + KL+KI Sbjct: 92 GSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKI 151 Query: 152 ETLRFAHNYIWALTETLRLADHCGGGGGG--LPGALFSEAVLLSPGGASAALSSSGDSPS 209 TL A NYI L +L+ G G G P L + LL+ S L+ P Sbjct: 152 ATLLLARNYILLLGSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPP 211 Query: 210 PA 211 A Sbjct: 212 DA 213 >gi|5031943 nescient helix loop helix 1 [Homo sapiens] Length = 133 Score = 54.7 bits (130), Expect = 9e-08 Identities = 51/131 (38%), Positives = 57/131 (43%), Gaps = 21/131 (16%) Query: 42 EEEPGAS--GGARRQRGAEAGQGARGGVAAGAEGCRPAR--LLGLVHDCKRRPSRARAVS 97 E E G S GG GA G G GG A G E P R L L + +RR RA A Sbjct: 18 ETESGFSDCGGGAGPDGAGPG-GPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKY 76 Query: 98 RGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFA 157 R A RER R+ N A LR++LPT P D KL+KIE LR A Sbjct: 77 RTAHAT----------------RERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLA 120 Query: 158 HNYIWALTETL 168 YI L L Sbjct: 121 ICYISYLNHVL 131 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.128 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,788,345 Number of Sequences: 37866 Number of extensions: 731571 Number of successful extensions: 8014 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 228 Number of HSP's successfully gapped in prelim test: 383 Number of HSP's that attempted gapping in prelim test: 6450 Number of HSP's gapped (non-prelim): 1647 length of query: 272 length of database: 18,247,518 effective HSP length: 101 effective length of query: 171 effective length of database: 14,423,052 effective search space: 2466341892 effective search space used: 2466341892 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.