Guide to the Human Genome
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Search of human proteins with 31077092

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31077092 neurogenin 2 [Homo sapiens]
         (272 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31077092 neurogenin 2 [Homo sapiens]                               546   e-156
gi|38455396 neurogenin 1 [Homo sapiens]                               130   1e-30
gi|68989258 neurogenin 3 [Homo sapiens]                               127   8e-30
gi|98986461 neurogenic differentiation 2 [Homo sapiens]                86   3e-17
gi|121114306 neurogenic differentiation 1 [Homo sapiens]               86   3e-17
gi|27475985 neurogenic differentiation 6 [Homo sapiens]                82   7e-16
gi|153792190 neurogenic differentiation 4 [Homo sapiens]               80   2e-15
gi|4885075 atonal homolog 1 [Homo sapiens]                             79   6e-15
gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]      72   4e-13
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    72   7e-13
gi|4507741 twist [Homo sapiens]                                        71   1e-12
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi...    71   1e-12
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo...    67   2e-11
gi|116805332 musculin [Homo sapiens]                                   65   8e-11
gi|21553337 atonal homolog 7 [Homo sapiens]                            64   1e-10
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]          63   2e-10
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    63   2e-10
gi|148922889 scleraxis homolog B [Homo sapiens]                        63   3e-10
gi|186972126 scleraxis homolog A [Homo sapiens]                        63   3e-10
gi|22748877 basic helix-loop-helix domain containing, class B, 5...    63   3e-10
gi|226498192 atonal homolog 8 [Homo sapiens]                           62   4e-10
gi|57529222 basic helix-loop-helix domain containing, class B, 4...    60   2e-09
gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]         60   3e-09
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi...    60   3e-09
gi|17981708 twist homolog 2 [Homo sapiens]                             59   3e-09
gi|23097242 nephew of atonal 3 [Homo sapiens]                          58   8e-09
gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]          55   5e-08
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H...    55   9e-08
gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]     55   9e-08
gi|5031943 nescient helix loop helix 1 [Homo sapiens]                  55   9e-08

>gi|31077092 neurogenin 2 [Homo sapiens]
          Length = 272

 Score =  546 bits (1408), Expect = e-156
 Identities = 272/272 (100%), Positives = 272/272 (100%)

Query: 1   MFVKSETLELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAG 60
           MFVKSETLELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAG
Sbjct: 1   MFVKSETLELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAG 60

Query: 61  QGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNR 120
           QGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNR
Sbjct: 61  QGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNR 120

Query: 121 ERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGG 180
           ERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGG
Sbjct: 121 ERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGG 180

Query: 181 LPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSP 240
           LPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSP
Sbjct: 181 LPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSP 240

Query: 241 ASPAGSDMDYWQPPPPDKHRYAPHLPIARDCI 272
           ASPAGSDMDYWQPPPPDKHRYAPHLPIARDCI
Sbjct: 241 ASPAGSDMDYWQPPPPDKHRYAPHLPIARDCI 272


>gi|38455396 neurogenin 1 [Homo sapiens]
          Length = 237

 Score =  130 bits (327), Expect = 1e-30
 Identities = 88/206 (42%), Positives = 113/206 (54%), Gaps = 23/206 (11%)

Query: 51  ARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIK 110
           AR Q+ A A  G       GA     A  +    D ++   R R  +R  ++   +  ++
Sbjct: 33  ARLQQAASAS-GPPAPARRGAPNISRASEVPGAQDDEQERRRRRGRTR-VRSEALLHSLR 90

Query: 111 KTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRL 170
           ++RR+KAN+RERNRMHNLNAALDALR VLP+FP+D KLTKIETLRFA+NYIWAL ETLRL
Sbjct: 91  RSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRL 150

Query: 171 ADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNS 230
           AD    GGG     L  + V   PG            PSPAS      S A ++S  S+ 
Sbjct: 151 ADQGLPGGGARERLLPPQCVPCLPG-----------PPSPASDAESWGSGAAAASPLSD- 198

Query: 231 TSPYSCTLSPASPAGSDMDYWQPPPP 256
                    P+SPA S+   ++P  P
Sbjct: 199 ---------PSSPAASEDFTYRPGDP 215


>gi|68989258 neurogenin 3 [Homo sapiens]
          Length = 214

 Score =  127 bits (320), Expect = 8e-30
 Identities = 92/200 (46%), Positives = 109/200 (54%), Gaps = 46/200 (23%)

Query: 64  RGGVAAGAEG-CRPARLLGLVHDCKRRPSRARAVSRGAKTAE-TVQRIKKTRRLKANNRE 121
           RG  A   EG CR A           R  RAR   R    +E  + + +++RR KAN+RE
Sbjct: 43  RGNCAEAEEGGCRGAP----------RKLRARRGGRSRPKSELALSKQRRSRRKKANDRE 92

Query: 122 RNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLAD--------- 172
           RNRMHNLN+ALDALR VLPTFP+DAKLTKIETLRFAHNYIWALT+TLR+AD         
Sbjct: 93  RNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSLYALEPP 152

Query: 173 --HCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNS 230
             HCG  G              SPGG      S GD  S  S  S   S +P++S+    
Sbjct: 153 APHCGELG--------------SPGG------SPGDWGSLYSPVSQAGSLSPAASLEERP 192

Query: 231 ---TSPYSCTLSPASPAGSD 247
               + +S  LSP S A SD
Sbjct: 193 GLLGATFSACLSPGSLAFSD 212


>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
          Length = 382

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 60/135 (44%), Positives = 73/135 (54%), Gaps = 12/135 (8%)

Query: 45  PGASGGARR--------QRGAEA--GQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRAR 94
           PGA G AR         + G EA   +    G   G E        GL      RP + R
Sbjct: 46  PGAPGPARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKK-R 104

Query: 95  AVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETL 154
              +   T   ++R  K RR KAN RERNRMH+LNAALD LR+V+P + +  KL+KIETL
Sbjct: 105 GPKKRKMTKARLER-SKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETL 163

Query: 155 RFAHNYIWALTETLR 169
           R A NYIWAL+E LR
Sbjct: 164 RLAKNYIWALSEILR 178


>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
          Length = 356

 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 47/85 (55%), Positives = 59/85 (69%), Gaps = 2/85 (2%)

Query: 85  DCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPE 144
           D  ++P R R   +   T   ++R K  RR+KAN RERNRMH LNAALD LR+V+P + +
Sbjct: 76  DDDQKPKR-RGPKKKKMTKARLERFK-LRRMKANARERNRMHGLNAALDNLRKVVPCYSK 133

Query: 145 DAKLTKIETLRFAHNYIWALTETLR 169
             KL+KIETLR A NYIWAL+E LR
Sbjct: 134 TQKLSKIETLRLAKNYIWALSEILR 158


>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
          Length = 337

 Score = 81.6 bits (200), Expect = 7e-16
 Identities = 43/79 (54%), Positives = 56/79 (70%), Gaps = 1/79 (1%)

Query: 92  RARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKI 151
           R R + +   T   ++R+K  RR +AN RERNRMH LN ALD LR+V+P + +  KL+KI
Sbjct: 75  RRRGLRKKKTTKLRLERVK-FRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKI 133

Query: 152 ETLRFAHNYIWALTETLRL 170
           ETLR A NYIWAL+E LR+
Sbjct: 134 ETLRLAKNYIWALSEILRI 152


>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
          Length = 331

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 62/170 (36%), Positives = 82/170 (48%), Gaps = 46/170 (27%)

Query: 9   ELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVA 68
           E+KEEE      G     L++LT    S +EEEEEE    G   ++RG +          
Sbjct: 30  EVKEEESRPGTYGM----LSSLTEEHDSIEEEEEEEE--DGEKPKRRGPK---------- 73

Query: 69  AGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNL 128
                             K++ ++AR           ++R +  RR+KAN RER RMH L
Sbjct: 74  ------------------KKKMTKAR-----------LERFR-ARRVKANARERTRMHGL 103

Query: 129 NAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCGGGG 178
           N ALD LR V+P + +  KL+KIETLR A NYIWAL+E L       G G
Sbjct: 104 NDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLETGQTPEGKG 153


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 78.6 bits (192), Expect = 6e-15
 Identities = 77/214 (35%), Positives = 98/214 (45%), Gaps = 27/214 (12%)

Query: 24  SPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLV 83
           SP L A     S A    +E  G     RR  G  +   + G V    + C+   L G V
Sbjct: 84  SPELGA-----SEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCK---LKGGV 135

Query: 84  HDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFP 143
              +   SR RA S     ++ V  ++K RRL AN RER RMH LN A D LR V+P+F 
Sbjct: 136 VVDELGCSRQRAPS-----SKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFN 190

Query: 144 EDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGGLPGA--------LFSEAVLLSPG 195
            D KL+K ETL+ A  YI AL+E L+     GG     P A        L + A      
Sbjct: 191 NDKKLSKYETLQMAQIYINALSELLQTPS--GGEQPPPPPASCKSDHHHLRTAASYEGGA 248

Query: 196 G---ASAALSSSGDSPSPASTWSC-TNSPAPSSS 225
           G   A+ A  +SG S  P    SC T   AP+S+
Sbjct: 249 GNATAAGAQQASGGSQRPTPPGSCRTRFSAPASA 282


>gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]
          Length = 272

 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 58/172 (33%), Positives = 73/172 (42%), Gaps = 35/172 (20%)

Query: 114 RLKANNRERNRMHNLNAALDALREVLPTF--PEDAKLTKIETLRFAHNYIWALTETL--- 168
           RLK N RER RMH+LN A+D LREV+P    P   KL+KI TL  A NYI  LT +L   
Sbjct: 85  RLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEM 144

Query: 169 -----------RLADHCG--GGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWS 215
                        A HCG  G   G P    +    + P    A  S +  SP  A++  
Sbjct: 145 KRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHPVHPILGGALSSGNASSPLSAASLP 204

Query: 216 CTNSPAPSSSVSSNSTSPYSCTLSPASPAGSDMDYW-----------QPPPP 256
              +  P  S+    ++P      PA   GS   +W            PPPP
Sbjct: 205 AIGTIRPPHSLLKAPSTP------PALQLGSGFQHWAGLPCPCTICQMPPPP 250


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 71.6 bits (174), Expect = 7e-13
 Identities = 78/264 (29%), Positives = 106/264 (40%), Gaps = 51/264 (19%)

Query: 2   FVKSETLELKEEEDVLVLLGSASPALA-ALTPLSSSADEEEEEEPGASGGARRQRGAEAG 60
           F+  +  E    +   +LL  A PA   AL P SS    E ++  G  GG   + GA  G
Sbjct: 52  FLSHQLHEYCYRDGACLLLQPAPPAAPLALAPPSSGGLGEPDD--GGGGGYCCETGAPPG 109

Query: 61  ---------QGARGGVAAGAEGCRP-ARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIK 110
                            AGA    P ARL GL          A A +R  +   +   ++
Sbjct: 110 GFPYSPGSPPSCLAYPCAGAAVLSPGARLRGL-------SGAAAAAARRRRRVRSEAELQ 162

Query: 111 KTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRL 170
           + R+  AN RER RM ++N A + LR  +PT P + +L+K++TLR A  YI  L+E ++ 
Sbjct: 163 QLRQA-ANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQA 221

Query: 171 ADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNS 230
                GGG G  G          PGG        GDSP                   S +
Sbjct: 222 DLPLRGGGAGGCG---------GPGGGGRL---GGDSP------------------GSQA 251

Query: 231 TSPYSCTLSPASPAGSDMDYWQPP 254
                C     SP+ SD DY  PP
Sbjct: 252 QKVIICHRGTRSPSPSDPDYGLPP 275


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 60/168 (35%), Positives = 85/168 (50%), Gaps = 29/168 (17%)

Query: 22  SASPALAALTPLSSSADEEEEEEP--GASGG-----ARRQRGAEAGQG--ARGGVAAGAE 72
           S+SP   A   LS+S +E + ++P  G  GG     +RR  G  AG G  A GGV  G E
Sbjct: 6   SSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDE 65

Query: 73  GCRPARLLGLVHDCKRRPSRARA-----------VSRGAKTAETVQRIKKTRRLKANNRE 121
              PA+        KR    A              S G  + ++ + ++ T+R+ AN RE
Sbjct: 66  PGSPAQ-------GKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQ-TQRVMANVRE 117

Query: 122 RNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLR 169
           R R  +LN A  ALR+++PT P D KL+KI+TL+ A  YI  L + L+
Sbjct: 118 RQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 164


>gi|29126247 basic helix-loop-helix family, member a15 [Homo
           sapiens]
          Length = 189

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 52/131 (39%), Positives = 65/131 (49%), Gaps = 15/131 (11%)

Query: 38  DEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVS 97
           D E     G   G+    G E  +G R   A  A     AR  G     +RRP  +    
Sbjct: 16  DTEATPGEGTPDGSLPNPGPEPAKGLRSRPARAA-----ARAPG--EGRRRRPGPS---G 65

Query: 98  RGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFA 157
            G +   ++QR     RL++N RER RMH LN A  ALREV+P    D KL+KIETL  A
Sbjct: 66  PGGRRDSSIQR-----RLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLA 120

Query: 158 HNYIWALTETL 168
            NYI +LT T+
Sbjct: 121 KNYIKSLTATI 131


>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
           sapiens]
          Length = 323

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 72/248 (29%), Positives = 104/248 (41%), Gaps = 26/248 (10%)

Query: 12  EEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGA 71
           E +D+ +   S   + +A T  + S+    +  P  S      RGA    GA  G   G 
Sbjct: 16  EPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSA---ELRGAMGSAGAHPGDKLGG 72

Query: 72  EGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAA 131
            G + +             S A A S      +  +   +  RLK N+RER RMH+LN A
Sbjct: 73  SGFKSSS-----SSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIA 127

Query: 132 LDALREVLPTF--PEDAKLTKIETLRFAHNYIWALTETL----RLADHCGGG--GGGLP- 182
           +D LREV+P    P   KL+KI TL  A NYI  LT +L    RL     GG   G  P 
Sbjct: 128 MDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPS 187

Query: 183 --GALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSP 240
             G L   A L +     AA + +   P+        + P    + ++ + +  +  +S 
Sbjct: 188 ACGGLAHSAPLPAATAHPAAAAHAAHHPA-------VHHPILPPAAAAAAAAAAAAAVSS 240

Query: 241 ASPAGSDM 248
           AS  GS +
Sbjct: 241 ASLPGSGL 248


>gi|116805332 musculin [Homo sapiens]
          Length = 206

 Score = 64.7 bits (156), Expect = 8e-11
 Identities = 50/145 (34%), Positives = 71/145 (48%), Gaps = 33/145 (22%)

Query: 34  SSSADEEE---EEE------PGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVH 84
           +SSA+EE+   EEE       G++ G +R+R   AG G  GG +AG  G +P    G   
Sbjct: 44  NSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGG-SAGGGGKKPLPAKGSAA 102

Query: 85  DCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPE 144
           +CK+                       ++R  AN RER RM  L+ A   L+  LP  P 
Sbjct: 103 ECKQ-----------------------SQRNAANARERARMRVLSKAFSRLKTSLPWVPP 139

Query: 145 DAKLTKIETLRFAHNYIWALTETLR 169
           D KL+K++TLR A +YI  L + L+
Sbjct: 140 DTKLSKLDTLRLASSYIAHLRQLLQ 164


>gi|21553337 atonal homolog 7 [Homo sapiens]
          Length = 152

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 38/77 (49%), Positives = 46/77 (59%), Gaps = 4/77 (5%)

Query: 99  GAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAH 158
           GA   E+  R    RRL AN RER RM  LN A D LR V+P + +D KL+K ETL+ A 
Sbjct: 31  GAGRLESAAR----RRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMAL 86

Query: 159 NYIWALTETLRLADHCG 175
           +YI ALT  L  A+  G
Sbjct: 87  SYIMALTRILAEAERFG 103


>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
          Length = 331

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 54/158 (34%), Positives = 71/158 (44%), Gaps = 25/158 (15%)

Query: 87  KRRPSRARA-VSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPED 145
           KRRPS     ++ G  T       K  RR+  N+RER R  N+N A   LR+++PT P D
Sbjct: 168 KRRPSPYEMEITDGPHT-------KVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPD 220

Query: 146 AKLTKIETLRFAHNYIWALTETLRLADH---------------CGGGGGGLPGALFSEAV 190
            KL+K E LR A  YI  L + L   +                 GGGGGG  G    + +
Sbjct: 221 KKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDL 280

Query: 191 LLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSS 228
           L      +++  SS D    AS  S T  PAP  +  S
Sbjct: 281 LQDVLSPNSSCGSSLD--GAASPDSYTEEPAPKHTARS 316


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 60/187 (32%), Positives = 72/187 (38%), Gaps = 41/187 (21%)

Query: 36  SADEEEEEEPGAS----GGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPS 91
           S DEE   E  AS    G       A  G G  GG  AG  G                  
Sbjct: 22  SEDEENRSESDASDQSFGCCEGPEAARRGPGPGGGRRAGGGG------------------ 63

Query: 92  RARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKI 151
                  GA     V++     R  AN RER+R  ++N A  ALR ++PT P D KL+KI
Sbjct: 64  -------GAGPVVVVRQ-----RQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKI 111

Query: 152 ETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPA 211
           ETLR A +YI  L   L L D    G      A        S  GA  A +  G  P   
Sbjct: 112 ETLRLASSYIAHLANVLLLGDSADDGQPCFRAA-------GSAKGAVPAAADGGRQPRSI 164

Query: 212 STWSCTN 218
            T+  +N
Sbjct: 165 CTFCLSN 171


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 52/160 (32%), Positives = 65/160 (40%), Gaps = 43/160 (26%)

Query: 34  SSSADEE----EEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRR 89
           SS +DE+         G  G  RR  G  AG G  GG                      R
Sbjct: 32  SSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGG----------------------R 69

Query: 90  PSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLT 149
           P R                 +  +R  AN RER+R +++N A  ALR ++PT P D KL+
Sbjct: 70  PGR-----------------EPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLS 112

Query: 150 KIETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFSEA 189
           KIETLR A +YI  L   L   + CG G     G  F  A
Sbjct: 113 KIETLRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHA 152


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 52/160 (32%), Positives = 65/160 (40%), Gaps = 43/160 (26%)

Query: 34  SSSADEE----EEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRR 89
           SS +DE+         G  G  RR  G  AG G  GG                      R
Sbjct: 32  SSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGG----------------------R 69

Query: 90  PSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLT 149
           P R                 +  +R  AN RER+R +++N A  ALR ++PT P D KL+
Sbjct: 70  PGR-----------------EPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLS 112

Query: 150 KIETLRFAHNYIWALTETLRLADHCGGGGGGLPGALFSEA 189
           KIETLR A +YI  L   L   + CG G     G  F  A
Sbjct: 113 KIETLRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHA 152


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 66/209 (31%), Positives = 83/209 (39%), Gaps = 37/209 (17%)

Query: 45  PGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAE 104
           PG  GG      +    G  GG  +G+ G                 S + + S   K+ E
Sbjct: 197 PGGLGGGGGGGSSSGSSGGGGGSGSGSGG-----------------SSSSSSSSSKKSKE 239

Query: 105 TVQRIKKTRRLKANNRERNRMHNLNAALDALREVLP--TFPEDAKLTKIETLRFAHNYI- 161
                +K  RL  N RER RMH+LN ALD LR V+P    P   KL+KI TL  A NYI 
Sbjct: 240 -----QKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYIL 294

Query: 162 ---WALTETLRLADHCGGG----GGGLPGALFSEAVLLSPGGASAALSSSGDSPSPAS-- 212
               AL E  RL  +   G       LP +  + A   +   A  A   +   P  A   
Sbjct: 295 MQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLP 354

Query: 213 -TWSCTNSPAPSSSVSSNSTSPYSCTLSP 240
              SC    A  +SVSS+      CT  P
Sbjct: 355 PAASCPEKCALFNSVSSSLCK--QCTEKP 381


>gi|226498192 atonal homolog 8 [Homo sapiens]
          Length = 321

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 36/86 (41%), Positives = 53/86 (61%), Gaps = 9/86 (10%)

Query: 87  KRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDA 146
           ++RP  A A S        ++ +++TRRL AN RER R+H ++AA +ALR+ +P +    
Sbjct: 211 RKRPGEATAAS------SEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQ 264

Query: 147 KLTKIETLRFAHNYIWALTETLRLAD 172
           KL+K+  LR A NYI +L    RLAD
Sbjct: 265 KLSKLAILRIACNYILSLA---RLAD 287


>gi|57529222 basic helix-loop-helix domain containing, class B, 4
           [Homo sapiens]
          Length = 225

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 67/209 (32%), Positives = 83/209 (39%), Gaps = 56/209 (26%)

Query: 23  ASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGL 82
           A+PA  A    + S+ E+  +E  A    RR+RG                        G 
Sbjct: 51  AAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGP-----------------------GS 87

Query: 83  VHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLP-- 140
             D +RRP   R++                 RL  N RER RMH+LN ALD LR V+P  
Sbjct: 88  AADGRRRPREQRSL-----------------RLSINARERRRMHDLNDALDGLRAVIPYA 130

Query: 141 TFPEDAKLTKIETLRFAHNYI----WALTETLRLADHCGGGGG------GLPGALFSEAV 190
             P   KL+KI TL  A NYI     AL E  RL      G G        P   F +A 
Sbjct: 131 HSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQAT 190

Query: 191 LLSPGGASAALSSSGDSPSPASTWSCTNS 219
            + P  A AAL   G  P   + +S T S
Sbjct: 191 -VCPFSAGAAL---GPCPDKCAAFSGTPS 215


>gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]
          Length = 193

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 56/168 (33%), Positives = 67/168 (39%), Gaps = 14/168 (8%)

Query: 86  CKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPED 145
           C RR   A A + G   A            + N RERNR+  +N    ALR+ +P     
Sbjct: 34  CSRRRRPATAETGGGAAAVA----------RRNERERNRVKLVNLGFQALRQHVPHGGAS 83

Query: 146 AKLTKIETLRFAHNYIWALTETLRLADHCGG--GGGGLPGALFSEAVLLSPGGASAALSS 203
            KL+K+ETLR A  YI AL   L   D       GG  P A+   A    PG    A S 
Sbjct: 84  KKLSKVETLRSAVEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASP 143

Query: 204 SGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSPASPAGSDMDYW 251
           S  S SP    S  + P    S  S+  S     LSPA     D   W
Sbjct: 144 SRASSSPGRGGS--SEPGSPRSAYSSDDSGCEGALSPAERELLDFSSW 189


>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
           sapiens]
          Length = 280

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 38/83 (45%), Positives = 44/83 (53%), Gaps = 5/83 (6%)

Query: 87  KRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDA 146
           KRRPS           AE  Q  K  RR+  N+RER R  N+N A   LR++LPT P D 
Sbjct: 130 KRRPSHCEL-----DLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDR 184

Query: 147 KLTKIETLRFAHNYIWALTETLR 169
           KL+K E LR A  YI  L   LR
Sbjct: 185 KLSKNEVLRLAMKYIGFLVRLLR 207


>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 45/151 (29%), Positives = 77/151 (50%), Gaps = 34/151 (22%)

Query: 21  GSASPALAALTPLSS--SADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPAR 78
           GS+SP    ++P+ S  +++EE E +P   G  RR     +  G+               
Sbjct: 4   GSSSP----VSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGS--------------- 44

Query: 79  LLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREV 138
                      P+  +   +G+ +A++ + ++ ++R+ AN RER R  +LN A  ALR++
Sbjct: 45  -----------PTPGKRGKKGSPSAQSFEELQ-SQRILANVRERQRTQSLNEAFAALRKI 92

Query: 139 LPTFPEDAKLTKIETLRFAHNYIWALTETLR 169
           +PT P D KL+KI+TL+ A  YI  L + L+
Sbjct: 93  IPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 122


>gi|23097242 nephew of atonal 3 [Homo sapiens]
          Length = 166

 Score = 58.2 bits (139), Expect = 8e-09
 Identities = 46/131 (35%), Positives = 57/131 (43%), Gaps = 34/131 (25%)

Query: 38  DEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVS 97
           D EEEE     G    +   E G+G                LLG       RP R R ++
Sbjct: 61  DPEEEECEVDQGDGEEEEEEERGRGVS--------------LLG-------RPKRKRVIT 99

Query: 98  RGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFA 157
              + A             AN RER RM NLN A D LR  +PTF  + +L++IETLR A
Sbjct: 100 YAQRQA-------------ANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLA 146

Query: 158 HNYIWALTETL 168
             YI  +TE L
Sbjct: 147 IVYISFMTELL 157


>gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]
          Length = 108

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 39/101 (38%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 112 TRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETL--R 169
           TR++  N RER R  N+N+A   LR+++PT P D KL+K ETLR A  YI  L + L  +
Sbjct: 2   TRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQ 61

Query: 170 LADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSP 210
                G    G    LF +   L PG     L  +   PSP
Sbjct: 62  SLQQTGVAAQGNILGLFPQGPHL-PGLEDRTLLENYQVPSP 101


>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
           sapiens]
          Length = 217

 Score = 54.7 bits (130), Expect = 9e-08
 Identities = 29/63 (46%), Positives = 38/63 (60%)

Query: 113 RRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLAD 172
           RR  AN +ER R  ++N+A   LRE +P  P D KL+KI+TLR A +YI  L + L   D
Sbjct: 100 RRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDD 159

Query: 173 HCG 175
             G
Sbjct: 160 QNG 162


>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
          Length = 271

 Score = 54.7 bits (130), Expect = 9e-08
 Identities = 41/122 (33%), Positives = 57/122 (46%), Gaps = 9/122 (7%)

Query: 99  GAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTF-------PEDAKLTKI 151
           G+   +  +  ++  R K N+RER RM +LN A+DALREV+  +           KL+KI
Sbjct: 92  GSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKI 151

Query: 152 ETLRFAHNYIWALTETLRLADHCGGGGGG--LPGALFSEAVLLSPGGASAALSSSGDSPS 209
            TL  A NYI  L  +L+      G G G   P  L +   LL+    S  L+     P 
Sbjct: 152 ATLLLARNYILLLGSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPP 211

Query: 210 PA 211
            A
Sbjct: 212 DA 213


>gi|5031943 nescient helix loop helix 1 [Homo sapiens]
          Length = 133

 Score = 54.7 bits (130), Expect = 9e-08
 Identities = 51/131 (38%), Positives = 57/131 (43%), Gaps = 21/131 (16%)

Query: 42  EEEPGAS--GGARRQRGAEAGQGARGGVAAGAEGCRPAR--LLGLVHDCKRRPSRARAVS 97
           E E G S  GG     GA  G G  GG A G E   P R  L  L  + +RR  RA A  
Sbjct: 18  ETESGFSDCGGGAGPDGAGPG-GPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKY 76

Query: 98  RGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFA 157
           R A                   RER R+   N A   LR++LPT P D KL+KIE LR A
Sbjct: 77  RTAHAT----------------RERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLA 120

Query: 158 HNYIWALTETL 168
             YI  L   L
Sbjct: 121 ICYISYLNHVL 131


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,788,345
Number of Sequences: 37866
Number of extensions: 731571
Number of successful extensions: 8014
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 228
Number of HSP's successfully gapped in prelim test: 383
Number of HSP's that attempted gapping in prelim test: 6450
Number of HSP's gapped (non-prelim): 1647
length of query: 272
length of database: 18,247,518
effective HSP length: 101
effective length of query: 171
effective length of database: 14,423,052
effective search space: 2466341892
effective search space used: 2466341892
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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