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Search of human proteins with 30795180
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30795180 zinc finger, FYVE domain containing 1 isoform 1
[Homo sapiens]
(777 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Hom... 1635 0.0
gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Hom... 787 0.0
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 74 7e-13
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 74 7e-13
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 74 7e-13
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 68 4e-11
gi|217272865 myotubularin related protein 4 [Homo sapiens] 67 6e-11
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 65 2e-10
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 65 2e-10
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 65 2e-10
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 65 2e-10
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 61 3e-09
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 61 5e-09
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 58 3e-08
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 58 4e-08
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 57 5e-08
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 57 5e-08
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 57 9e-08
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 57 9e-08
gi|13375827 phafin 2 [Homo sapiens] 55 2e-07
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 54 7e-07
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens] 54 7e-07
gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens] 53 9e-07
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 53 1e-06
gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens] 53 1e-06
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 52 2e-06
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 52 2e-06
gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens] 52 2e-06
gi|153791377 apoptosis-inducing protein D [Homo sapiens] 51 4e-06
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 51 5e-06
>gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Homo
sapiens]
Length = 777
Score = 1635 bits (4233), Expect = 0.0
Identities = 777/777 (100%), Positives = 777/777 (100%)
Query: 1 MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHER 60
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHER
Sbjct: 1 MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHER 60
Query: 61 IRLKPGHVPYCDLCKGLSGHLPGVRQRAIVRCQTCKINLCLECQKRTHSGGNKRRHPVTV 120
IRLKPGHVPYCDLCKGLSGHLPGVRQRAIVRCQTCKINLCLECQKRTHSGGNKRRHPVTV
Sbjct: 61 IRLKPGHVPYCDLCKGLSGHLPGVRQRAIVRCQTCKINLCLECQKRTHSGGNKRRHPVTV 120
Query: 121 YNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL 180
YNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
Sbjct: 121 YNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL 180
Query: 181 KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLL 240
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLL
Sbjct: 181 KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLL 240
Query: 241 GATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTA 300
GATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTA
Sbjct: 241 GATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTA 300
Query: 301 RCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK 360
RCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
Sbjct: 301 RCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK 360
Query: 361 GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSS 420
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSS
Sbjct: 361 GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSS 420
Query: 421 FFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGE 480
FFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGE
Sbjct: 421 FFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGE 480
Query: 481 EVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIV 540
EVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIV
Sbjct: 481 EVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIV 540
Query: 541 HVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQ 600
HVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQ
Sbjct: 541 HVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQ 600
Query: 601 ILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNV 660
ILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNV
Sbjct: 601 ILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNV 660
Query: 661 QLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILH 720
QLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILH
Sbjct: 661 QLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILH 720
Query: 721 CHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL 777
CHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL
Sbjct: 721 CHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL 777
>gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Homo
sapiens]
Length = 362
Score = 787 bits (2033), Expect = 0.0
Identities = 362/362 (100%), Positives = 362/362 (100%)
Query: 416 MAHSSFFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKAC 475
MAHSSFFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKAC
Sbjct: 1 MAHSSFFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKAC 60
Query: 476 YERGEEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVV 535
YERGEEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVV
Sbjct: 61 YERGEEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVV 120
Query: 536 RTEIVHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYW 595
RTEIVHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYW
Sbjct: 121 RTEIVHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYW 180
Query: 596 RPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCY 655
RPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCY
Sbjct: 181 RPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCY 240
Query: 656 EARNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPD 715
EARNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPD
Sbjct: 241 EARNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPD 300
Query: 716 HEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPG 775
HEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPG
Sbjct: 301 HEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPG 360
Query: 776 DL 777
DL
Sbjct: 361 DL 362
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 73.6 bits (179), Expect = 7e-13
Identities = 33/69 (47%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 703 VKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDH 762
V A + W+ D E HC C KEFSI KHHCR CG FC+ CS + A+PS +
Sbjct: 522 VNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPS--YPK 579
Query: 763 PVRVCFNCN 771
PVRVC +C+
Sbjct: 580 PVRVCDSCH 588
Score = 60.5 bits (145), Expect = 6e-09
Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W + + C +C F + KHHCR CG FC++CSS +P P PVRVCD+C
Sbjct: 531 WLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSY---PKPVRVCDSC 587
Query: 655 Y 655
+
Sbjct: 588 H 588
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 73.6 bits (179), Expect = 7e-13
Identities = 33/69 (47%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 703 VKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDH 762
V A + W+ D E HC C KEFSI KHHCR CG FC+ CS + A+PS +
Sbjct: 522 VNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPS--YPK 579
Query: 763 PVRVCFNCN 771
PVRVC +C+
Sbjct: 580 PVRVCDSCH 588
Score = 60.5 bits (145), Expect = 6e-09
Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W + + C +C F + KHHCR CG FC++CSS +P P PVRVCD+C
Sbjct: 531 WLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSY---PKPVRVCDSC 587
Query: 655 Y 655
+
Sbjct: 588 H 588
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 73.6 bits (179), Expect = 7e-13
Identities = 33/69 (47%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 703 VKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDH 762
V A + W+ D E HC C KEFSI KHHCR CG FC+ CS + A+PS +
Sbjct: 630 VNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPS--YPK 687
Query: 763 PVRVCFNCN 771
PVRVC +C+
Sbjct: 688 PVRVCDSCH 696
Score = 60.5 bits (145), Expect = 6e-09
Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W + + C +C F + KHHCR CG FC++CSS +P P PVRVCD+C
Sbjct: 639 WLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSY---PKPVRVCDSC 695
Query: 655 Y 655
+
Sbjct: 696 H 696
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 67.8 bits (164), Expect = 4e-11
Identities = 29/60 (48%), Positives = 37/60 (61%), Gaps = 2/60 (3%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCN 771
W+ D E HC C KEFS+ KHHCR CG+ FC+ CS + +PS PVRVC +C+
Sbjct: 572 WLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSS--PKPVRVCDSCH 629
Score = 63.5 bits (153), Expect = 7e-10
Identities = 26/61 (42%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W + + C C F + KHHCR CGE FC++CS P+P P PVRVCD+C
Sbjct: 572 WLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPS---SPKPVRVCDSC 628
Query: 655 Y 655
+
Sbjct: 629 H 629
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 67.0 bits (162), Expect = 6e-11
Identities = 27/59 (45%), Positives = 34/59 (57%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNC 770
WVPDH HC+NC EF + +HHCR CG FC C H + +P + PV VC +C
Sbjct: 1111 WVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSC 1169
Score = 51.6 bits (122), Expect = 3e-06
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W P+ C C F +HHCR CG FC C P+P++ PV VC++C
Sbjct: 1111 WVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYD-PVLVCNSC 1169
Query: 655 YEARNVQLA 663
YE V A
Sbjct: 1170 YEHIQVSRA 1178
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 65.5 bits (158), Expect = 2e-10
Identities = 26/59 (44%), Positives = 33/59 (55%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNC 770
W+PDH HC+ C F + KHHCR CG FC C + + VPS+ P RVC +C
Sbjct: 1079 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSC 1137
Score = 55.8 bits (133), Expect = 1e-07
Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W P+ C C ++F KHHCR CG FC SC ++ PVP + P RVC +C
Sbjct: 1079 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLF-EPSRVCKSC 1137
Query: 655 YEARNVQLAVTEAQVD 670
Y + + + + ++D
Sbjct: 1138 YSSLHPTSSSIDLELD 1153
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 65.5 bits (158), Expect = 2e-10
Identities = 26/59 (44%), Positives = 33/59 (55%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNC 770
W+PDH HC+ C F + KHHCR CG FC C + + VPS+ P RVC +C
Sbjct: 1116 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSC 1174
Score = 55.8 bits (133), Expect = 1e-07
Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W P+ C C ++F KHHCR CG FC SC ++ PVP + P RVC +C
Sbjct: 1116 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLF-EPSRVCKSC 1174
Query: 655 YEARNVQLAVTEAQVD 670
Y + + + + ++D
Sbjct: 1175 YSSLHPTSSSIDLELD 1190
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 65.1 bits (157), Expect = 2e-10
Identities = 30/65 (46%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 706 AARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVR 765
A R WV E CH CR +F + KHHCRACGQ FC +CS +P G + VR
Sbjct: 154 AERAPDWVDAEE---CHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVR 210
Query: 766 VCFNC 770
VC C
Sbjct: 211 VCEPC 215
Score = 59.7 bits (143), Expect = 1e-08
Identities = 27/56 (48%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 604 CNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARN 659
C++C F KHHCRACG+ FC CSSK +P+ G VRVC+ CYE N
Sbjct: 166 CHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGI-EKEVRVCEPCYEQLN 220
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 65.1 bits (157), Expect = 2e-10
Identities = 28/66 (42%), Positives = 35/66 (53%)
Query: 705 DAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPV 764
D P WVPD C C+ F++ KHHCR+CG+ FC CS +P G PV
Sbjct: 807 DFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPV 866
Query: 765 RVCFNC 770
RVC +C
Sbjct: 867 RVCTHC 872
Score = 61.6 bits (148), Expect = 3e-09
Identities = 28/64 (43%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Query: 592 PAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVC 651
P W P+ C C F KHHCR+CG+ FC CSS + P+P G PVRVC
Sbjct: 811 PPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYG-QVKPVRVC 869
Query: 652 DNCY 655
+CY
Sbjct: 870 THCY 873
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 61.2 bits (147), Expect = 3e-09
Identities = 27/59 (45%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNC 770
W D+E+ +C C K FS+ + +HHCR CG FC ECS PS PVRVC C
Sbjct: 1349 WAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSS--KKPVRVCDAC 1405
Score = 56.2 bits (134), Expect = 1e-07
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 3/61 (4%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W ++++ +C C F +HHCR CG FC CS+K P PVRVCD C
Sbjct: 1349 WAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPS---SKKPVRVCDAC 1405
Query: 655 Y 655
+
Sbjct: 1406 F 1406
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 60.8 bits (146), Expect = 5e-09
Identities = 25/76 (32%), Positives = 39/76 (51%)
Query: 697 DIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVP 756
+I G +D+ YW+PD + C++C ++F+ +HHCR CGQ FC C +
Sbjct: 140 EIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGK 199
Query: 757 SRGWDHPVRVCFNCNK 772
G+ +R C C K
Sbjct: 200 FMGYTGDLRACTYCRK 215
Score = 51.6 bits (122), Expect = 3e-06
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 594 YWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDN 653
YW P+SQ C C+ F +HHCR CG+ FC C ++ P G+ +R C
Sbjct: 154 YWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGY-TGDLRACTY 212
Query: 654 C 654
C
Sbjct: 213 C 213
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 58.2 bits (139), Expect = 3e-08
Identities = 24/59 (40%), Positives = 29/59 (49%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNC 770
WVPD E C C +F KHHCR CG+ FCD C + + + PVR C C
Sbjct: 41 WVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCAEC 99
Score = 51.2 bits (121), Expect = 4e-06
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W P+ + C +C F KHHCR CG+ FCD C S+ P+ R PVR C C
Sbjct: 41 WVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPL-RRMCFVDPVRQCAEC 99
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 57.8 bits (138), Expect = 4e-08
Identities = 26/68 (38%), Positives = 33/68 (48%), Gaps = 9/68 (13%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCR---------ACGQGFCDECSHDRRAVPSRGWDH 762
W+PDH HC+ C F + KHHCR CG FC C + + VPS+
Sbjct: 1079 WLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSCCNQKVPVPSQQLFE 1138
Query: 763 PVRVCFNC 770
P RVC +C
Sbjct: 1139 PSRVCKSC 1146
Score = 48.1 bits (113), Expect = 3e-05
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 10/85 (11%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRA---------CGEGFCDSCSSKTRPVPERGWGP 645
W P+ C C ++F KHHCR CG FC SC ++ PVP +
Sbjct: 1079 WLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSCCNQKVPVPSQQLF- 1137
Query: 646 APVRVCDNCYEARNVQLAVTEAQVD 670
P RVC +CY + + + + ++D
Sbjct: 1138 EPSRVCKSCYSSLHPTSSSIDLELD 1162
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 57.4 bits (137), Expect = 5e-08
Identities = 25/60 (41%), Positives = 31/60 (51%)
Query: 711 YWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNC 770
+WV D C C FS+ +HHCR CGQ FC +CS + + PVRVC NC
Sbjct: 205 HWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNC 264
Score = 55.8 bits (133), Expect = 1e-07
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 9/110 (8%)
Query: 551 KDNNNAAQRLLDGMNFMAQSVSELSLGPTKA-VTSW-LTDQ---IAPAYWRPNSQILSCN 605
KDN + A+ G++ + S + +G ++ V SW ++DQ A +W + SC+
Sbjct: 160 KDNAHPAEVTALGIS---KDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCS 216
Query: 606 KCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCY 655
C+ F + +HHCR CG+ FC CS + +R +PVRVC NCY
Sbjct: 217 GCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEI-KRLKISSPVRVCQNCY 265
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 57.4 bits (137), Expect = 5e-08
Identities = 25/60 (41%), Positives = 31/60 (51%)
Query: 711 YWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNC 770
+WV D C C FS+ +HHCR CGQ FC +CS + + PVRVC NC
Sbjct: 3450 HWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNC 3509
Score = 55.8 bits (133), Expect = 1e-07
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 9/110 (8%)
Query: 551 KDNNNAAQRLLDGMNFMAQSVSELSLGPTKA-VTSW-LTDQ---IAPAYWRPNSQILSCN 605
KDN + A+ G++ + S + +G ++ V SW ++DQ A +W + SC+
Sbjct: 3405 KDNAHPAEVTALGIS---KDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCS 3461
Query: 606 KCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCY 655
C+ F + +HHCR CG+ FC CS + +R +PVRVC NCY
Sbjct: 3462 GCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEI-KRLKISSPVRVCQNCY 3510
Score = 30.0 bits (66), Expect = 8.6
Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 6/54 (11%)
Query: 527 NQDPVDTVVRTEIVHVWPGTDGFLKDNNNAAQRLLD------GMNFMAQSVSEL 574
N D + EIV ++ G FLKD+++ +Q LLD G NF+ + L
Sbjct: 267 NMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRL 320
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 56.6 bits (135), Expect = 9e-08
Identities = 28/70 (40%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 701 GLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGW 760
GLV +P WVPD E +C NC+ +F+ +HHCRACG+ FC C + R +
Sbjct: 734 GLVLGQKQPT-WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCN--RKCKLQYL 790
Query: 761 DHPVRVCFNC 770
+ RVC C
Sbjct: 791 EKEARVCVVC 800
Score = 48.9 bits (115), Expect = 2e-05
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 3/62 (4%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W P+S+ +C C F +HHCRACG+ FC C ++ + + RVC C
Sbjct: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQ---YLEKEARVCVVC 800
Query: 655 YE 656
YE
Sbjct: 801 YE 802
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 56.6 bits (135), Expect = 9e-08
Identities = 28/70 (40%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 701 GLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGW 760
GLV +P WVPD E +C NC+ +F+ +HHCRACG+ FC C + R +
Sbjct: 734 GLVLGQKQPT-WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCN--RKCKLQYL 790
Query: 761 DHPVRVCFNC 770
+ RVC C
Sbjct: 791 EKEARVCVVC 800
Score = 48.9 bits (115), Expect = 2e-05
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 3/62 (4%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W P+S+ +C C F +HHCRACG+ FC C ++ + + RVC C
Sbjct: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQ---YLEKEARVCVVC 800
Query: 655 YE 656
YE
Sbjct: 801 YE 802
>gi|13375827 phafin 2 [Homo sapiens]
Length = 249
Score = 55.5 bits (132), Expect = 2e-07
Identities = 31/85 (36%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Query: 687 NTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRK-EFSIKLSKHHCRACGQGFC 745
N + VT + G A WVPD E C C+K +F+ +HHCR CG C
Sbjct: 124 NHINKCVTDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVC 183
Query: 746 DECSHDRRAVPSRGWDHPVRVCFNC 770
CS R +PS+ PVR+C C
Sbjct: 184 GPCSEKRFLLPSQS-SKPVRICDFC 207
Score = 53.5 bits (127), Expect = 7e-07
Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 593 AYWRPNSQILSCNKCATS-FKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVC 651
A W P+S+ C +C + F + +HHCR CG C CS K +P + PVR+C
Sbjct: 147 AVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQ--SSKPVRIC 204
Query: 652 DNCYE 656
D CY+
Sbjct: 205 DFCYD 209
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 53.5 bits (127), Expect = 7e-07
Identities = 33/93 (35%), Positives = 41/93 (44%), Gaps = 5/93 (5%)
Query: 570 SVSELSLGPTKAVTSWLTDQIAPA--YWRPNSQILSCNKCATS-FKDNDTKHHCRACGEG 626
S+ E S PT+ ++ PA W P+ C C F + +HHCR CG
Sbjct: 1782 SLRERSFPPTQPSQEFVPPATPPARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRL 1841
Query: 627 FCDSCSSKTRPVPERGWGPAPVRVCDNCYEARN 659
C SCS+K V G P RVCD CY N
Sbjct: 1842 VCSSCSTKKMVV--EGCRENPARVCDQCYSYCN 1872
Score = 47.0 bits (110), Expect = 7e-05
Identities = 27/71 (38%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 703 VKDAARPA--YWVPDHEILHCHNC-RKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRG 759
V A PA WVPD C C R+ F++ +HHCR CG+ C CS ++ V
Sbjct: 1798 VPPATPPARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCS-TKKMVVEGC 1856
Query: 760 WDHPVRVCFNC 770
++P RVC C
Sbjct: 1857 RENPARVCDQC 1867
>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
Length = 1430
Score = 53.5 bits (127), Expect = 7e-07
Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 6/72 (8%)
Query: 699 PLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSR 758
PLG ++ W+PD C C EF++ +HHCRACG+ C CS ++ +
Sbjct: 1211 PLG-----SKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYL 1265
Query: 759 GWDHPVRVCFNC 770
+ P RVC +C
Sbjct: 1266 K-NQPARVCEHC 1276
Score = 48.9 bits (115), Expect = 2e-05
Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNC 654
W P+++ C C + F +HHCRACG+ C +CSS + PA RVC++C
Sbjct: 1219 WIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPA--RVCEHC 1276
Query: 655 YE 656
++
Sbjct: 1277 FQ 1278
>gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens]
Length = 410
Score = 53.1 bits (126), Expect = 9e-07
Identities = 29/66 (43%), Positives = 34/66 (51%), Gaps = 12/66 (18%)
Query: 603 SCNKCATSFKDN-----DTK------HHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVC 651
SC KC F N DTK HHCR CG+ C CSSK P G+ VRVC
Sbjct: 286 SCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPVMGF-EFQVRVC 344
Query: 652 DNCYEA 657
D+CY++
Sbjct: 345 DSCYDS 350
Score = 50.4 bits (119), Expect = 6e-06
Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 11/61 (18%)
Query: 721 CHNCRKEF-----------SIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFN 769
C C + F ++ L +HHCR CGQ C +CS R + P G++ VRVC +
Sbjct: 287 CQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPVMGFEFQVRVCDS 346
Query: 770 C 770
C
Sbjct: 347 C 347
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 52.8 bits (125), Expect = 1e-06
Identities = 36/108 (33%), Positives = 51/108 (47%), Gaps = 4/108 (3%)
Query: 589 QIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPV 648
++AP W P+SQ +C KC F +HHCRACG+ FC SC S + A
Sbjct: 691 EVAPV-WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEA-- 747
Query: 649 RVCDNCYEA-RNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTA 695
RVC C+ NV + +V G L +V +A + T+ +A
Sbjct: 748 RVCVICHSVLMNVAQPREQRRVWFADGILPNGEVADAAKLTMNGTSSA 795
Score = 48.9 bits (115), Expect = 2e-05
Identities = 17/37 (45%), Positives = 22/37 (59%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDEC 748
WVPD + +C C F+ +HHCRACG+ FC C
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASC 732
>gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens]
Length = 400
Score = 52.8 bits (125), Expect = 1e-06
Identities = 53/176 (30%), Positives = 75/176 (42%), Gaps = 36/176 (20%)
Query: 509 IECPNCGVVYRSRQYWFGNQ----DPVDTVVRT----EIVHVWP-----GTDGFLKDNNN 555
+E NC +V R + G DPV V+ + V +W GT L+ +N+
Sbjct: 184 LEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHND 243
Query: 556 AAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTD---QIAPAYWRPNSQILSCNKCATSFK 612
Q L ++ + +S G + W D Q P + +S C KC F
Sbjct: 244 RVQAL----SYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDS----CQKCDQPFF 295
Query: 613 DN-----DTK------HHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEA 657
N D+K HHCR CG+ C CSSK +P G+ VRVCD+C+EA
Sbjct: 296 WNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGF-EFEVRVCDSCHEA 350
Score = 50.8 bits (120), Expect = 5e-06
Identities = 19/43 (44%), Positives = 29/43 (67%)
Query: 730 IKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNK 772
I L +HHCR CG+ C +CS R ++P G++ VRVC +C++
Sbjct: 307 IGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHE 349
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 52.0 bits (123), Expect = 2e-06
Identities = 22/45 (48%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 589 QIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSS 633
++AP W P+SQ +C KC F +HHCRACG+ FC SC S
Sbjct: 691 EVAPV-WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCS 734
Score = 48.9 bits (115), Expect = 2e-05
Identities = 17/37 (45%), Positives = 22/37 (59%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDEC 748
WVPD + +C C F+ +HHCRACG+ FC C
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASC 732
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 52.0 bits (123), Expect = 2e-06
Identities = 22/45 (48%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 589 QIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSS 633
++AP W P+SQ +C KC F +HHCRACG+ FC SC S
Sbjct: 691 EVAPV-WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCS 734
Score = 48.9 bits (115), Expect = 2e-05
Identities = 17/37 (45%), Positives = 22/37 (59%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDEC 748
WVPD + +C C F+ +HHCRACG+ FC C
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASC 732
>gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]
Length = 1462
Score = 52.0 bits (123), Expect = 2e-06
Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 8/138 (5%)
Query: 635 TRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQVDDEGGTLIARKVGEAVQ-NTLGAVV 693
+RPV E+ + ++C + L+ + DE ++R + E + L A
Sbjct: 1165 SRPVMEKVPYALKIETSESC-----LMLSASSCAERDEWYGCLSRALPEDYKAQALAAFH 1219
Query: 694 TAIDIPLGL-VKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDR 752
+++I L V RP VP ++ C NC +FS+ L +HHC ACG+ C CS ++
Sbjct: 1220 HSVEIRERLGVSLGERPPTLVPVTHVMMCMNCGCDFSLTLRRHHCHACGKIVCRNCSRNK 1279
Query: 753 RAVPSRGWDHPVRVCFNC 770
+ D +VC C
Sbjct: 1280 YPLKYLK-DRMAKVCDGC 1296
Score = 42.7 bits (99), Expect = 0.001
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
Query: 597 PNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCY 655
P + ++ C C F +HHC ACG+ C +CS P+ + +VCD C+
Sbjct: 1241 PVTHVMMCMNCGCDFSLTLRRHHCHACGKIVCRNCSRNKYPL--KYLKDRMAKVCDGCF 1297
>gi|153791377 apoptosis-inducing protein D [Homo sapiens]
Length = 279
Score = 51.2 bits (121), Expect = 4e-06
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
Query: 587 TDQIAPAYWRPNSQILSCNKCA-TSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGP 645
T+ AP W P+ C +C T F +HHCR CG C CS + +P P
Sbjct: 143 TEHAAP--WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPR--LSP 198
Query: 646 APVRVCDNCYEARNVQLAVTEAQVDDEG 673
PVRVC CY Q EA+ G
Sbjct: 199 KPVRVCSLCYRELAAQQRQEEAEEQGAG 226
Score = 50.1 bits (118), Expect = 8e-06
Identities = 27/65 (41%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 710 AYWVPDHEILHCHNCRK-EFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCF 768
A W+PD C C + FS +HHCR CG C ECS R +P R PVRVC
Sbjct: 147 APWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLP-RLSPKPVRVCS 205
Query: 769 NCNKK 773
C ++
Sbjct: 206 LCYRE 210
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 50.8 bits (120), Expect = 5e-06
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query: 712 WVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCN 771
W+ D E HC +C++EFS + +HHCR CG+ FC C ++ V S+ R C C
Sbjct: 1170 WLGDTEANHCLDCKREFSWMVRRHHCRICGRIFCYYCCNN--YVLSKHGGKKERCCRACF 1227
Query: 772 KK 773
+K
Sbjct: 1228 QK 1229
Score = 33.5 bits (75), Expect = 0.77
Identities = 13/37 (35%), Positives = 17/37 (45%)
Query: 595 WRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSC 631
W +++ C C F +HHCR CG FC C
Sbjct: 1170 WLGDTEANHCLDCKREFSWMVRRHHCRICGRIFCYYC 1206
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,240,767
Number of Sequences: 37866
Number of extensions: 1615061
Number of successful extensions: 6759
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 6406
Number of HSP's gapped (non-prelim): 448
length of query: 777
length of database: 18,247,518
effective HSP length: 110
effective length of query: 667
effective length of database: 14,082,258
effective search space: 9392866086
effective search space used: 9392866086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.