Guide to the Human Genome
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Search of human proteins with 30410801

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30410801 activator of cAMP-responsive element modulator
(CREM) in testis [Homo sapiens]
         (284 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30410801 activator of cAMP-responsive element modulator (CREM...   645   0.0  
gi|87159836 four and a half LIM domains 2 [Homo sapiens]              406   e-114
gi|87159834 four and a half LIM domains 2 [Homo sapiens]              406   e-114
gi|42403575 four and a half LIM domains 2 [Homo sapiens]              406   e-114
gi|87159832 four and a half LIM domains 2 [Homo sapiens]              406   e-114
gi|54112385 four and a half LIM domains 3 [Homo sapiens]              336   1e-92
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]   290   8e-79
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]   290   8e-79
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]   290   8e-79
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]   290   8e-79
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]    290   8e-79
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]   252   3e-67
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]   180   1e-45
gi|221316659 leupaxin isoform 1 [Homo sapiens]                        121   6e-28
gi|4758670 leupaxin isoform 2 [Homo sapiens]                          121   6e-28
gi|170932518 paxillin isoform 3 [Homo sapiens]                        120   1e-27
gi|170932516 paxillin isoform 2 [Homo sapiens]                        120   1e-27
gi|170932514 paxillin isoform 1 [Homo sapiens]                        120   1e-27
gi|109638745 transforming growth factor beta 1 induced transcrip...   112   3e-25
gi|21361591 transforming growth factor beta 1 induced transcript...   112   3e-25
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ...   108   5e-24
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo...   107   9e-24
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo...   107   9e-24
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo...   107   9e-24
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor...   107   9e-24
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]            106   2e-23
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]             106   2e-23
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]            101   7e-22
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]            101   7e-22
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]      100   1e-21

>gi|30410801 activator of cAMP-responsive element modulator (CREM)
           in testis [Homo sapiens]
          Length = 284

 Score =  645 bits (1664), Expect = 0.0
 Identities = 284/284 (100%), Positives = 284/284 (100%)

Query: 1   MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDR 60
           MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDR
Sbjct: 1   MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDR 60

Query: 61  HWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKG 120
           HWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKG
Sbjct: 61  HWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKG 120

Query: 121 NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ 180
           NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ
Sbjct: 121 NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ 180

Query: 181 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICF 240
           LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICF
Sbjct: 181 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICF 240

Query: 241 QDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI 284
           QDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI
Sbjct: 241 QDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI 284


>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  406 bits (1044), Expect = e-114
 Identities = 165/275 (60%), Positives = 217/275 (78%)

Query: 3   TAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHW 62
           T  F C +C  SL GKKY+L+++SPYCV C++ +F+N CEEC KPI  D KDL YKDRHW
Sbjct: 2   TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61

Query: 63  HEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNY 122
           HE CF C++C +SLV+KPFAAK+++LLCT+CYSNE SSKC  CK+TIMPG+RKME+KG+ 
Sbjct: 62  HEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSS 121

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLW 182
           WHETCF+C  C+QPIGTK  I K++ N+CVPC+EK+ A  C  CKK IT+GG+T+ +Q W
Sbjct: 122 WHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPW 181

Query: 183 HKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQD 242
           HKECF+C+ CRK L  ++F +RDD+ +C++C+  LYA KC  C+ PISGL G K+I F++
Sbjct: 182 HKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEE 241

Query: 243 SQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCG 277
            QWH++CFNC KCS+SLVG+GFLT+  +I C  CG
Sbjct: 242 RQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCG 276



 Score = 78.2 bits (191), Expect = 8e-15
 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 2/94 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  C + L  ++++ R++ P+C+ C+  L+AN C  C KPI      K + ++D  
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIG--CDCKDLSYKDRH 60

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGS 278
           WH  CF+C +C  SLV K F  +  ++ C  C S
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94


>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  406 bits (1044), Expect = e-114
 Identities = 165/275 (60%), Positives = 217/275 (78%)

Query: 3   TAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHW 62
           T  F C +C  SL GKKY+L+++SPYCV C++ +F+N CEEC KPI  D KDL YKDRHW
Sbjct: 2   TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61

Query: 63  HEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNY 122
           HE CF C++C +SLV+KPFAAK+++LLCT+CYSNE SSKC  CK+TIMPG+RKME+KG+ 
Sbjct: 62  HEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSS 121

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLW 182
           WHETCF+C  C+QPIGTK  I K++ N+CVPC+EK+ A  C  CKK IT+GG+T+ +Q W
Sbjct: 122 WHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPW 181

Query: 183 HKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQD 242
           HKECF+C+ CRK L  ++F +RDD+ +C++C+  LYA KC  C+ PISGL G K+I F++
Sbjct: 182 HKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEE 241

Query: 243 SQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCG 277
            QWH++CFNC KCS+SLVG+GFLT+  +I C  CG
Sbjct: 242 RQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCG 276



 Score = 78.2 bits (191), Expect = 8e-15
 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 2/94 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  C + L  ++++ R++ P+C+ C+  L+AN C  C KPI      K + ++D  
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIG--CDCKDLSYKDRH 60

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGS 278
           WH  CF+C +C  SLV K F  +  ++ C  C S
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94


>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  406 bits (1044), Expect = e-114
 Identities = 165/275 (60%), Positives = 217/275 (78%)

Query: 3   TAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHW 62
           T  F C +C  SL GKKY+L+++SPYCV C++ +F+N CEEC KPI  D KDL YKDRHW
Sbjct: 2   TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61

Query: 63  HEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNY 122
           HE CF C++C +SLV+KPFAAK+++LLCT+CYSNE SSKC  CK+TIMPG+RKME+KG+ 
Sbjct: 62  HEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSS 121

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLW 182
           WHETCF+C  C+QPIGTK  I K++ N+CVPC+EK+ A  C  CKK IT+GG+T+ +Q W
Sbjct: 122 WHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPW 181

Query: 183 HKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQD 242
           HKECF+C+ CRK L  ++F +RDD+ +C++C+  LYA KC  C+ PISGL G K+I F++
Sbjct: 182 HKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEE 241

Query: 243 SQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCG 277
            QWH++CFNC KCS+SLVG+GFLT+  +I C  CG
Sbjct: 242 RQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCG 276



 Score = 78.2 bits (191), Expect = 8e-15
 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 2/94 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  C + L  ++++ R++ P+C+ C+  L+AN C  C KPI      K + ++D  
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIG--CDCKDLSYKDRH 60

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGS 278
           WH  CF+C +C  SLV K F  +  ++ C  C S
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94


>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  406 bits (1044), Expect = e-114
 Identities = 165/275 (60%), Positives = 217/275 (78%)

Query: 3   TAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHW 62
           T  F C +C  SL GKKY+L+++SPYCV C++ +F+N CEEC KPI  D KDL YKDRHW
Sbjct: 2   TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61

Query: 63  HEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNY 122
           HE CF C++C +SLV+KPFAAK+++LLCT+CYSNE SSKC  CK+TIMPG+RKME+KG+ 
Sbjct: 62  HEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSS 121

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLW 182
           WHETCF+C  C+QPIGTK  I K++ N+CVPC+EK+ A  C  CKK IT+GG+T+ +Q W
Sbjct: 122 WHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPW 181

Query: 183 HKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQD 242
           HKECF+C+ CRK L  ++F +RDD+ +C++C+  LYA KC  C+ PISGL G K+I F++
Sbjct: 182 HKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEE 241

Query: 243 SQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCG 277
            QWH++CFNC KCS+SLVG+GFLT+  +I C  CG
Sbjct: 242 RQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCG 276



 Score = 78.2 bits (191), Expect = 8e-15
 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 2/94 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  C + L  ++++ R++ P+C+ C+  L+AN C  C KPI      K + ++D  
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIG--CDCKDLSYKDRH 60

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGS 278
           WH  CF+C +C  SLV K F  +  ++ C  C S
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score =  336 bits (862), Expect = 1e-92
 Identities = 131/271 (48%), Positives = 184/271 (67%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C  SL G+KY+  D  PYCV CYD  F+N C EC++ I  DS++L Y+DRH+HEG
Sbjct: 5   FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF+C +C  SL ++PF  +D  LLC +CY +  SS+C  C  T+MPGSRK+E+ G  WHE
Sbjct: 65  CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHE 124

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185
            CF+C  C QP+G++  +  +  +YCVPC+E +FA  C  C K +T GG+T+ DQ WH+E
Sbjct: 125 HCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWHRE 184

Query: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQW 245
           C +C+GC+  L  +QF SRD+ P+C+ C+  L+A KC +C +PI GL G K++ F+D  W
Sbjct: 185 CLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHW 244

Query: 246 HSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           H  CF+C +CS SLVG+GF+    ++ CQ C
Sbjct: 245 HHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275



 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 2/92 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C+ C + L   +++  D  P+C+ CY++ +AN C  C + I     ++ + ++D  
Sbjct: 3   ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIG--HDSRELFYEDRH 60

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           +H  CF C +C  SL  + F  Q+ E+ C  C
Sbjct: 61  FHEGCFRCCRCQRSLADEPFTCQDSELLCNDC 92



 Score = 30.4 bits (67), Expect = 1.8
 Identities = 11/30 (36%), Positives = 18/30 (60%)

Query: 247 SECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           SE F+C KC+ SL G+ ++  +   +C  C
Sbjct: 2   SESFDCAKCNESLYGRKYIQTDSGPYCVPC 31


>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  290 bits (743), Expect = 8e-79
 Identities = 121/272 (44%), Positives = 168/272 (61%), Gaps = 1/272 (0%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C YC   L GKKYV KD    C+ C+D+  +N C EC+KPI +DSK++ YK+R WH+ 
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF+C KC H L  + F AKD ++LC +C + E S KC  C + I+ G + +E+KG  WH+
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185
            CF C NC+Q IGT     K    YCV C E +FA +C  C K ITSGGIT+ DQ WH +
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAD 184

Query: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGL-TGAKFICFQDSQ 244
           CF+C  C K L  ++F + +D  +C+DCY +  A KC  C  PI+G   G+  + ++   
Sbjct: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 244

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           WH  CF+C KCSV+L  K F+   ++++C  C
Sbjct: 245 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276



 Score =  108 bits (271), Expect = 4e-24
 Identities = 49/155 (31%), Positives = 76/155 (49%), Gaps = 5/155 (3%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C   +    +  K +  YCVTC++  F+ +C +C K I S    + Y+D+ WH  
Sbjct: 127 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITYQDQPWHAD 184

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIM---PGSRKMEFKGNY 122
           CF C  C+  L  + F A +++  C +CY N  + KC  CK  I     GS  + ++G  
Sbjct: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 244

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEK 157
           WH+ CF C+ C   +  K  +  +   YC  C +K
Sbjct: 245 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  CR  L  ++++ +D +  C+ C++   AN CV C KPI     +K + +++  
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282
           WH  CF C KC   L  + F+ ++ +I C KC +  D+
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98


>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  290 bits (743), Expect = 8e-79
 Identities = 121/272 (44%), Positives = 168/272 (61%), Gaps = 1/272 (0%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C YC   L GKKYV KD    C+ C+D+  +N C EC+KPI +DSK++ YK+R WH+ 
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF+C KC H L  + F AKD ++LC +C + E S KC  C + I+ G + +E+KG  WH+
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185
            CF C NC+Q IGT     K    YCV C E +FA +C  C K ITSGGIT+ DQ WH +
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAD 184

Query: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGL-TGAKFICFQDSQ 244
           CF+C  C K L  ++F + +D  +C+DCY +  A KC  C  PI+G   G+  + ++   
Sbjct: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 244

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           WH  CF+C KCSV+L  K F+   ++++C  C
Sbjct: 245 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276



 Score =  108 bits (271), Expect = 4e-24
 Identities = 49/155 (31%), Positives = 76/155 (49%), Gaps = 5/155 (3%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C   +    +  K +  YCVTC++  F+ +C +C K I S    + Y+D+ WH  
Sbjct: 127 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITYQDQPWHAD 184

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIM---PGSRKMEFKGNY 122
           CF C  C+  L  + F A +++  C +CY N  + KC  CK  I     GS  + ++G  
Sbjct: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 244

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEK 157
           WH+ CF C+ C   +  K  +  +   YC  C +K
Sbjct: 245 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  CR  L  ++++ +D +  C+ C++   AN CV C KPI     +K + +++  
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282
           WH  CF C KC   L  + F+ ++ +I C KC +  D+
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98


>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
          Length = 309

 Score =  290 bits (743), Expect = 8e-79
 Identities = 121/272 (44%), Positives = 168/272 (61%), Gaps = 1/272 (0%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C YC   L GKKYV KD    C+ C+D+  +N C EC+KPI +DSK++ YK+R WH+ 
Sbjct: 34  FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF+C KC H L  + F AKD ++LC +C + E S KC  C + I+ G + +E+KG  WH+
Sbjct: 94  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 153

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185
            CF C NC+Q IGT     K    YCV C E +FA +C  C K ITSGGIT+ DQ WH +
Sbjct: 154 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAD 213

Query: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGL-TGAKFICFQDSQ 244
           CF+C  C K L  ++F + +D  +C+DCY +  A KC  C  PI+G   G+  + ++   
Sbjct: 214 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 273

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           WH  CF+C KCSV+L  K F+   ++++C  C
Sbjct: 274 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 305



 Score =  108 bits (271), Expect = 4e-24
 Identities = 49/155 (31%), Positives = 76/155 (49%), Gaps = 5/155 (3%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C   +    +  K +  YCVTC++  F+ +C +C K I S    + Y+D+ WH  
Sbjct: 156 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITYQDQPWHAD 213

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIM---PGSRKMEFKGNY 122
           CF C  C+  L  + F A +++  C +CY N  + KC  CK  I     GS  + ++G  
Sbjct: 214 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 273

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEK 157
           WH+ CF C+ C   +  K  +  +   YC  C +K
Sbjct: 274 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 308



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  CR  L  ++++ +D +  C+ C++   AN CV C KPI     +K + +++  
Sbjct: 32  EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 89

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282
           WH  CF C KC   L  + F+ ++ +I C KC +  D+
Sbjct: 90  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 127


>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
          Length = 296

 Score =  290 bits (743), Expect = 8e-79
 Identities = 121/272 (44%), Positives = 168/272 (61%), Gaps = 1/272 (0%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C YC   L GKKYV KD    C+ C+D+  +N C EC+KPI +DSK++ YK+R WH+ 
Sbjct: 21  FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF+C KC H L  + F AKD ++LC +C + E S KC  C + I+ G + +E+KG  WH+
Sbjct: 81  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 140

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185
            CF C NC+Q IGT     K    YCV C E +FA +C  C K ITSGGIT+ DQ WH +
Sbjct: 141 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAD 200

Query: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGL-TGAKFICFQDSQ 244
           CF+C  C K L  ++F + +D  +C+DCY +  A KC  C  PI+G   G+  + ++   
Sbjct: 201 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 260

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           WH  CF+C KCSV+L  K F+   ++++C  C
Sbjct: 261 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 292



 Score =  108 bits (271), Expect = 4e-24
 Identities = 49/155 (31%), Positives = 76/155 (49%), Gaps = 5/155 (3%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C   +    +  K +  YCVTC++  F+ +C +C K I S    + Y+D+ WH  
Sbjct: 143 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITYQDQPWHAD 200

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIM---PGSRKMEFKGNY 122
           CF C  C+  L  + F A +++  C +CY N  + KC  CK  I     GS  + ++G  
Sbjct: 201 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 260

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEK 157
           WH+ CF C+ C   +  K  +  +   YC  C +K
Sbjct: 261 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  CR  L  ++++ +D +  C+ C++   AN CV C KPI     +K + +++  
Sbjct: 19  EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 76

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282
           WH  CF C KC   L  + F+ ++ +I C KC +  D+
Sbjct: 77  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 114


>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  290 bits (743), Expect = 8e-79
 Identities = 121/272 (44%), Positives = 168/272 (61%), Gaps = 1/272 (0%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C YC   L GKKYV KD    C+ C+D+  +N C EC+KPI +DSK++ YK+R WH+ 
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF+C KC H L  + F AKD ++LC +C + E S KC  C + I+ G + +E+KG  WH+
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185
            CF C NC+Q IGT     K    YCV C E +FA +C  C K ITSGGIT+ DQ WH +
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAD 184

Query: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGL-TGAKFICFQDSQ 244
           CF+C  C K L  ++F + +D  +C+DCY +  A KC  C  PI+G   G+  + ++   
Sbjct: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 244

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           WH  CF+C KCSV+L  K F+   ++++C  C
Sbjct: 245 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276



 Score =  108 bits (271), Expect = 4e-24
 Identities = 49/155 (31%), Positives = 76/155 (49%), Gaps = 5/155 (3%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C   +    +  K +  YCVTC++  F+ +C +C K I S    + Y+D+ WH  
Sbjct: 127 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITYQDQPWHAD 184

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIM---PGSRKMEFKGNY 122
           CF C  C+  L  + F A +++  C +CY N  + KC  CK  I     GS  + ++G  
Sbjct: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQS 244

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEK 157
           WH+ CF C+ C   +  K  +  +   YC  C +K
Sbjct: 245 WHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  CR  L  ++++ +D +  C+ C++   AN CV C KPI     +K + +++  
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282
           WH  CF C KC   L  + F+ ++ +I C KC +  D+
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98


>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
          Length = 323

 Score =  252 bits (643), Expect = 3e-67
 Identities = 106/226 (46%), Positives = 142/226 (62%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C YC   L GKKYV KD    C+ C+D+  +N C EC+KPI +DSK++ YK+R WH+ 
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF+C KC H L  + F AKD ++LC +C + E S KC  C + I+ G + +E+KG  WH+
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185
            CF C NC+Q IGT     K    YCV C E +FA +C  C K ITSGGIT+ DQ WH +
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAD 184

Query: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISG 231
           CF+C  C K L  ++F + +D  +C+DCY +  A KC  C  PI+G
Sbjct: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230



 Score =  151 bits (382), Expect = 5e-37
 Identities = 64/212 (30%), Positives = 108/212 (50%), Gaps = 6/212 (2%)

Query: 67  FKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHET 126
           F C  C   L  K +  KD    C +C+   C++ C  C++ I   S+++ +K  +WH+T
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 127 CFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSG--GITFCDQLWHK 184
           CF C  C  P+  +  ++K++   C  C  +E +  C  C K I +G   + +   +WHK
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           +CF CS C++ +    F  + +  +C+ C+   +A  CV C+K I+    +  I +QD  
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAIT----SGGITYQDQP 180

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           WH++CF C  CS  L G+ F     + +C  C
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDC 212



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  CR  L  ++++ +D +  C+ C++   AN CV C KPI     +K + +++  
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282
           WH  CF C KC   L  + F+ ++ +I C KC +  D+
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98


>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
          Length = 194

 Score =  180 bits (456), Expect = 1e-45
 Identities = 76/163 (46%), Positives = 101/163 (61%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C YC   L GKKYV KD    C+ C+D+  +N C EC+KPI +DSK++ YK+R WH+ 
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF+C KC H L  + F AKD ++LC +C + E S KC  C + I+ G + +E+KG  WH+
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKK 168
            CF C NC+Q IGT     K    YCV C E +FA +C  C K
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167



 Score =  120 bits (301), Expect = 1e-27
 Identities = 48/163 (29%), Positives = 84/163 (51%), Gaps = 2/163 (1%)

Query: 67  FKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHET 126
           F C  C   L  K +  KD    C +C+   C++ C  C++ I   S+++ +K  +WH+T
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 127 CFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSG--GITFCDQLWHK 184
           CF C  C  P+  +  ++K++   C  C  +E +  C  C K I +G   + +   +WHK
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSK 227
           +CF CS C++ +    F  + +  +C+ C+   +A  CV C+K
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167



 Score = 95.9 bits (237), Expect = 4e-20
 Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 4/151 (2%)

Query: 128 FVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVI--TSGGITFCDQLWHKE 185
           F C  CR P+  K  + K+  + C+ CF+K  A+ C  C+K I   S  + + ++ WH  
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQW 245
           CF C+ C   L  E F+++D+   C  C     + KC  C K I  + G + + ++ + W
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI--VAGDQNVEYKGTVW 122

Query: 246 HSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           H +CF C  C   +    F  + ++ +C  C
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
           E F C  CR  L  ++++ +D +  C+ C++   AN CV C KPI     +K + +++  
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60

Query: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282
           WH  CF C KC   L  + F+ ++ +I C KC +  D+
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score =  121 bits (304), Expect = 6e-28
 Identities = 66/237 (27%), Positives = 96/237 (40%), Gaps = 8/237 (3%)

Query: 40  YCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECS 99
           +C  C+KPI    K +    + WH   F CT C   +   PF  +     C   Y    S
Sbjct: 156 HCASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFS 213

Query: 100 SKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEF 159
            +C +C   I+   + +      WH   F C +C +  G +    K+   YC   F   F
Sbjct: 214 PRCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 271

Query: 160 AHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYA 219
           +  C  C + +    ++  D +WH ECF+C  C        F   D  PFC   Y+H   
Sbjct: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331

Query: 220 NKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
             C  C +PI+G    + I     ++H E F C  C   L    F  QN + +CQ C
Sbjct: 332 TLCHGCGQPITG----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPC 384



 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 55/214 (25%), Positives = 88/214 (41%), Gaps = 4/214 (1%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C +C   +    +  +    YC   Y ++FS  C  C  PI    K L   ++ WH 
Sbjct: 180 HFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILD--KVLTAMNQTWHP 237

Query: 65  GCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
             F C+ C      + F  KD++  C + +    S KC  C R ++     +      WH
Sbjct: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVWH 295

Query: 125 ETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHK 184
             CFVC +C     T      +   +C   +       C+ C + IT   I+     +H 
Sbjct: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHP 355

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218
           E F+C+ C   L +  F  ++D  +C  C+N L+
Sbjct: 356 EHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score =  121 bits (304), Expect = 6e-28
 Identities = 66/237 (27%), Positives = 96/237 (40%), Gaps = 8/237 (3%)

Query: 40  YCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECS 99
           +C  C+KPI    K +    + WH   F CT C   +   PF  +     C   Y    S
Sbjct: 151 HCASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFS 208

Query: 100 SKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEF 159
            +C +C   I+   + +      WH   F C +C +  G +    K+   YC   F   F
Sbjct: 209 PRCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 266

Query: 160 AHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYA 219
           +  C  C + +    ++  D +WH ECF+C  C        F   D  PFC   Y+H   
Sbjct: 267 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 326

Query: 220 NKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
             C  C +PI+G    + I     ++H E F C  C   L    F  QN + +CQ C
Sbjct: 327 TLCHGCGQPITG----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPC 379



 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 55/214 (25%), Positives = 88/214 (41%), Gaps = 4/214 (1%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C +C   +    +  +    YC   Y ++FS  C  C  PI    K L   ++ WH 
Sbjct: 175 HFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILD--KVLTAMNQTWHP 232

Query: 65  GCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
             F C+ C      + F  KD++  C + +    S KC  C R ++     +      WH
Sbjct: 233 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVWH 290

Query: 125 ETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHK 184
             CFVC +C     T      +   +C   +       C+ C + IT   I+     +H 
Sbjct: 291 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHP 350

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218
           E F+C+ C   L +  F  ++D  +C  C+N L+
Sbjct: 351 EHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score =  120 bits (302), Expect = 1e-27
 Identities = 70/241 (29%), Positives = 97/241 (40%), Gaps = 8/241 (3%)

Query: 36  VFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYS 95
           V    C  CKKPI         K   WH   F CT C   +  + F  +D +  C + Y 
Sbjct: 186 VAKGVCGACKKPIAGQVVTAMGKT--WHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 243

Query: 96  NECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCF 155
           N  S +C++C   I+   + +      WH   F C  C    G +    K+   YC   +
Sbjct: 244 NLFSPRCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDY 301

Query: 156 EKEFAHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYN 215
              FA  C  C + I    I+  + LWH ECF+C  C        F   D  P+C   Y+
Sbjct: 302 FDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 361

Query: 216 HLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQK 275
               + C  C KPI+G    + I     ++H E F C  C   L    F  QN + +CQ 
Sbjct: 362 ERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 417

Query: 276 C 276
           C
Sbjct: 418 C 418



 Score =  119 bits (299), Expect = 2e-27
 Identities = 63/214 (29%), Positives = 94/214 (43%), Gaps = 4/214 (1%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C +C   +  + +  +D  PYC   Y  +FS  C  C  PI    K +   DR WH 
Sbjct: 214 HFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILD--KVVTALDRTWHP 271

Query: 65  GCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
             F C +C      + F  KD +  C + Y +  + KC  C R I+     +      WH
Sbjct: 272 EHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLWH 329

Query: 125 ETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHK 184
             CFVC  C  P         +   YC   + +     C+ C+K IT   IT   + +H 
Sbjct: 330 PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHP 389

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218
           E F+C+ C K L +  F  ++D P+C +C+  L+
Sbjct: 390 EHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score =  120 bits (302), Expect = 1e-27
 Identities = 70/241 (29%), Positives = 97/241 (40%), Gaps = 8/241 (3%)

Query: 36  VFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYS 95
           V    C  CKKPI         K   WH   F CT C   +  + F  +D +  C + Y 
Sbjct: 319 VAKGVCGACKKPIAGQVVTAMGKT--WHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 376

Query: 96  NECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCF 155
           N  S +C++C   I+   + +      WH   F C  C    G +    K+   YC   +
Sbjct: 377 NLFSPRCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDY 434

Query: 156 EKEFAHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYN 215
              FA  C  C + I    I+  + LWH ECF+C  C        F   D  P+C   Y+
Sbjct: 435 FDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 494

Query: 216 HLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQK 275
               + C  C KPI+G    + I     ++H E F C  C   L    F  QN + +CQ 
Sbjct: 495 ERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 550

Query: 276 C 276
           C
Sbjct: 551 C 551



 Score =  119 bits (299), Expect = 2e-27
 Identities = 63/214 (29%), Positives = 94/214 (43%), Gaps = 4/214 (1%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C +C   +  + +  +D  PYC   Y  +FS  C  C  PI    K +   DR WH 
Sbjct: 347 HFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILD--KVVTALDRTWHP 404

Query: 65  GCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
             F C +C      + F  KD +  C + Y +  + KC  C R I+     +      WH
Sbjct: 405 EHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLWH 462

Query: 125 ETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHK 184
             CFVC  C  P         +   YC   + +     C+ C+K IT   IT   + +H 
Sbjct: 463 PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHP 522

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218
           E F+C+ C K L +  F  ++D P+C +C+  L+
Sbjct: 523 EHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score =  120 bits (302), Expect = 1e-27
 Identities = 70/241 (29%), Positives = 97/241 (40%), Gaps = 8/241 (3%)

Query: 36  VFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYS 95
           V    C  CKKPI         K   WH   F CT C   +  + F  +D +  C + Y 
Sbjct: 353 VAKGVCGACKKPIAGQVVTAMGKT--WHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 410

Query: 96  NECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCF 155
           N  S +C++C   I+   + +      WH   F C  C    G +    K+   YC   +
Sbjct: 411 NLFSPRCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDY 468

Query: 156 EKEFAHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYN 215
              FA  C  C + I    I+  + LWH ECF+C  C        F   D  P+C   Y+
Sbjct: 469 FDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 528

Query: 216 HLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQK 275
               + C  C KPI+G    + I     ++H E F C  C   L    F  QN + +CQ 
Sbjct: 529 ERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 584

Query: 276 C 276
           C
Sbjct: 585 C 585



 Score =  119 bits (299), Expect = 2e-27
 Identities = 63/214 (29%), Positives = 94/214 (43%), Gaps = 4/214 (1%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C +C   +  + +  +D  PYC   Y  +FS  C  C  PI    K +   DR WH 
Sbjct: 381 HFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILD--KVVTALDRTWHP 438

Query: 65  GCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
             F C +C      + F  KD +  C + Y +  + KC  C R I+     +      WH
Sbjct: 439 EHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLWH 496

Query: 125 ETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHK 184
             CFVC  C  P         +   YC   + +     C+ C+K IT   IT   + +H 
Sbjct: 497 PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHP 556

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218
           E F+C+ C K L +  F  ++D P+C +C+  L+
Sbjct: 557 EHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score =  112 bits (281), Expect = 3e-25
 Identities = 64/236 (27%), Positives = 96/236 (40%), Gaps = 8/236 (3%)

Query: 41  CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSS 100
           C  C KPI      +    R WH   F C  C+ +L    F  KD    C ECY    S 
Sbjct: 228 CGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 285

Query: 101 KCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFA 160
           +C  C + I    + +   G +WH   F C +C +P G +    +E   YC   F + FA
Sbjct: 286 RCGFCNQPIR--HKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343

Query: 161 HYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYAN 220
             C  C+  I    I+    LWH +CF+C  C        F   +  P C + ++    +
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403

Query: 221 KCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
            C  C  P++G    + +     ++H + F C  C   L    F  +  + +CQ C
Sbjct: 404 LCATCGLPVTG----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 455



 Score =  103 bits (258), Expect = 1e-22
 Identities = 56/214 (26%), Positives = 85/214 (39%), Gaps = 4/214 (1%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C  C+ +L G  +  KD +P+C  CY   FS  C  C +PI    K +     HWH 
Sbjct: 251 HFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWHP 308

Query: 65  GCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
             F C  C     ++ F  ++ R  C   +    + +C  C+  I+     +      WH
Sbjct: 309 EHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALWH 366

Query: 125 ETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHK 184
             CFVC  C  P         E    C   F       C  C   +T   ++   + +H 
Sbjct: 367 PDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHP 426

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218
           + F C+ C + L +  F  R   P+C  C+  L+
Sbjct: 427 DHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 460


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score =  112 bits (281), Expect = 3e-25
 Identities = 64/236 (27%), Positives = 96/236 (40%), Gaps = 8/236 (3%)

Query: 41  CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSS 100
           C  C KPI      +    R WH   F C  C+ +L    F  KD    C ECY    S 
Sbjct: 211 CGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268

Query: 101 KCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFA 160
           +C  C + I    + +   G +WH   F C +C +P G +    +E   YC   F + FA
Sbjct: 269 RCGFCNQPIR--HKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326

Query: 161 HYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYAN 220
             C  C+  I    I+    LWH +CF+C  C        F   +  P C + ++    +
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386

Query: 221 KCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
            C  C  P++G    + +     ++H + F C  C   L    F  +  + +CQ C
Sbjct: 387 LCATCGLPVTG----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438



 Score =  103 bits (258), Expect = 1e-22
 Identities = 56/214 (26%), Positives = 85/214 (39%), Gaps = 4/214 (1%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C  C+ +L G  +  KD +P+C  CY   FS  C  C +PI    K +     HWH 
Sbjct: 234 HFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWHP 291

Query: 65  GCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
             F C  C     ++ F  ++ R  C   +    + +C  C+  I+     +      WH
Sbjct: 292 EHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALWH 349

Query: 125 ETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHK 184
             CFVC  C  P         E    C   F       C  C   +T   ++   + +H 
Sbjct: 350 PDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHP 409

Query: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218
           + F C+ C + L +  F  R   P+C  C+  L+
Sbjct: 410 DHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443


>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 325

 Score =  108 bits (270), Expect = 5e-24
 Identities = 68/277 (24%), Positives = 111/277 (40%), Gaps = 15/277 (5%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C        +   +   YC   +  +F+  C +C + I    + +   +  WH  
Sbjct: 36  FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIG--RVIKAMNNSWHPE 93

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSK-----CFHCKRTIMPGSRKMEFKG 120
           CF+C  C   L +  F     R LC  C++ E +       C  C   I    + + FK 
Sbjct: 94  CFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFKN 151

Query: 121 NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ 180
           + +H   F C NC + + T      +   YC+PC +K     C  C++ I    +    +
Sbjct: 152 DPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGK 210

Query: 181 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICF 240
            WH E F+C+ C K     +   R    +C   YN L+ + C  C++ I G      +  
Sbjct: 211 QWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG----DVVSA 266

Query: 241 QDSQWHSECFNCGKCSVSLVGKG-FLTQNKEIFCQKC 276
            +  W   CF C  C+  L  K  F+  + +  C+KC
Sbjct: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKC 303



 Score =  102 bits (255), Expect = 3e-22
 Identities = 59/239 (24%), Positives = 98/239 (41%), Gaps = 12/239 (5%)

Query: 41  CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSS 100
           CE CK       K +      +HE CF C +C     E  F   + R  C   +    + 
Sbjct: 10  CERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAP 69

Query: 101 KCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFA 160
            C  C   I+   R ++   N WH  CF C+ C++ +     +     + C PC  +E A
Sbjct: 70  CCHQCGEFII--GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKA 127

Query: 161 -----HYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYN 215
                + C  C  +I    + F +  +H + F C+ C K+L  +    + +  +C+ C++
Sbjct: 128 RGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGEL-YCLPCHD 186

Query: 216 HLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQ 274
            +    C AC +PI G    + +     QWH E F C KC    +G     +    +C+
Sbjct: 187 KMGVPICGACRRPIEG----RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCE 241



 Score = 85.1 bits (209), Expect = 6e-17
 Identities = 51/188 (27%), Positives = 74/188 (39%), Gaps = 4/188 (2%)

Query: 99  SSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKE 158
           S+ C  CK    P  + +   G  +HE CFVC  C Q          E   YC   F+  
Sbjct: 7   SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66

Query: 159 FAHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218
           FA  C+ C + I    I   +  WH ECF C  C++ L +  F+       C  C+N   
Sbjct: 67  FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126

Query: 219 ANKC--VACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           A       C K    +   + + F++  +H + FNC  C   L       +  E++C  C
Sbjct: 127 ARGLGKYICQK-CHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKG-ELYCLPC 184

Query: 277 GSGMDTDI 284
              M   I
Sbjct: 185 HDKMGVPI 192



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 3/91 (3%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C  C    LG ++  +    YC T Y+++F + C  C + IE D   +   ++ W  
Sbjct: 216 HFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDV--VSALNKAWCV 273

Query: 65  GCFKCTKCNHSL-VEKPFAAKDERLLCTECY 94
            CF C+ CN  L ++  F   D + +C +CY
Sbjct: 274 NCFACSTCNTKLTLKNKFVEFDMKPVCKKCY 304


>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
           1 [Homo sapiens]
          Length = 363

 Score =  107 bits (268), Expect = 9e-24
 Identities = 65/275 (23%), Positives = 116/275 (42%), Gaps = 11/275 (4%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C        +   +   YC   +  +F+  C  C + I    + +   + +WH G
Sbjct: 63  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPG 120

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKC--FHCKRT-IMPGSRKMEFKGNY 122
           CF+C  C+  L +  F     R LC  C++ E +     + C+R  ++   + + F+ + 
Sbjct: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDA 180

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLW 182
           +H   F C +C + + T      +   YC+PC +K     C  C++ I    +    + W
Sbjct: 181 YHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQW 239

Query: 183 HKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQD 242
           H E F+C+ C K     +   +    +C   YN L+ + C  CS  I G      +   +
Sbjct: 240 HVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSALN 295

Query: 243 SQWHSECFNCGKCSVSLVGKG-FLTQNKEIFCQKC 276
             W   CF+C  C+  L  K  F+  + +  C++C
Sbjct: 296 KAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRC 330



 Score = 97.8 bits (242), Expect = 9e-21
 Identities = 60/246 (24%), Positives = 98/246 (39%), Gaps = 12/246 (4%)

Query: 34  DRVFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTEC 93
           D + +  C+ C+       + +      +HE CF C +C     E  F   + R  C   
Sbjct: 30  DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 89

Query: 94  YSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVP 153
           +    +  C  C   I+   R ++   N WH  CF CE C   +     +     + C P
Sbjct: 90  FQMLFAPCCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147

Query: 154 CFEKEFA-----HYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYP 208
           C  +E A     + C  C  VI    + F    +H + F C+ C K+L  E    + +  
Sbjct: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL- 206

Query: 209 FCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQN 268
           +C+ C++ +    C AC +PI G    + +     QWH E F C KC    +G     + 
Sbjct: 207 YCLPCHDKMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKK 262

Query: 269 KEIFCQ 274
              +C+
Sbjct: 263 GLAYCE 268



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 50/188 (26%), Positives = 70/188 (37%), Gaps = 10/188 (5%)

Query: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAH 161
           C  C+    P  R +   G  +HE CFVC  C +P         E   YC   F+  FA 
Sbjct: 37  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96

Query: 162 YCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANK 221
            C  C + I    I   +  WH  CF C  C  +L +  F+       C  C+N   A  
Sbjct: 97  CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156

Query: 222 -----CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
                C  C   I      + + F+   +H + FNC  C   L  +    +  E++C  C
Sbjct: 157 LGKYICQRCHLVID----EQPLMFRSDAYHPDHFNCTHCGKELTAEARELKG-ELYCLPC 211

Query: 277 GSGMDTDI 284
              M   I
Sbjct: 212 HDKMGVPI 219



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 3/91 (3%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C  C    LG ++  K    YC T Y+++F + C  C   IE D   +   ++ W  
Sbjct: 243 HFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWCV 300

Query: 65  GCFKCTKCNHSL-VEKPFAAKDERLLCTECY 94
            CF C+ CN  L ++  F   D + +C  CY
Sbjct: 301 SCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 331


>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
           5 [Homo sapiens]
          Length = 336

 Score =  107 bits (268), Expect = 9e-24
 Identities = 65/275 (23%), Positives = 116/275 (42%), Gaps = 11/275 (4%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C        +   +   YC   +  +F+  C  C + I    + +   + +WH G
Sbjct: 36  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPG 93

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKC--FHCKRT-IMPGSRKMEFKGNY 122
           CF+C  C+  L +  F     R LC  C++ E +     + C+R  ++   + + F+ + 
Sbjct: 94  CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDA 153

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLW 182
           +H   F C +C + + T      +   YC+PC +K     C  C++ I    +    + W
Sbjct: 154 YHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQW 212

Query: 183 HKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQD 242
           H E F+C+ C K     +   +    +C   YN L+ + C  CS  I G      +   +
Sbjct: 213 HVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSALN 268

Query: 243 SQWHSECFNCGKCSVSLVGKG-FLTQNKEIFCQKC 276
             W   CF+C  C+  L  K  F+  + +  C++C
Sbjct: 269 KAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRC 303



 Score = 97.8 bits (242), Expect = 9e-21
 Identities = 60/246 (24%), Positives = 98/246 (39%), Gaps = 12/246 (4%)

Query: 34  DRVFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTEC 93
           D + +  C+ C+       + +      +HE CF C +C     E  F   + R  C   
Sbjct: 3   DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 62

Query: 94  YSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVP 153
           +    +  C  C   I+   R ++   N WH  CF CE C   +     +     + C P
Sbjct: 63  FQMLFAPCCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 120

Query: 154 CFEKEFA-----HYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYP 208
           C  +E A     + C  C  VI    + F    +H + F C+ C K+L  E    + +  
Sbjct: 121 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL- 179

Query: 209 FCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQN 268
           +C+ C++ +    C AC +PI G    + +     QWH E F C KC    +G     + 
Sbjct: 180 YCLPCHDKMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKK 235

Query: 269 KEIFCQ 274
              +C+
Sbjct: 236 GLAYCE 241



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 50/188 (26%), Positives = 70/188 (37%), Gaps = 10/188 (5%)

Query: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAH 161
           C  C+    P  R +   G  +HE CFVC  C +P         E   YC   F+  FA 
Sbjct: 10  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 69

Query: 162 YCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANK 221
            C  C + I    I   +  WH  CF C  C  +L +  F+       C  C+N   A  
Sbjct: 70  CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 129

Query: 222 -----CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
                C  C   I      + + F+   +H + FNC  C   L  +    +  E++C  C
Sbjct: 130 LGKYICQRCHLVID----EQPLMFRSDAYHPDHFNCTHCGKELTAEARELKG-ELYCLPC 184

Query: 277 GSGMDTDI 284
              M   I
Sbjct: 185 HDKMGVPI 192



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 3/91 (3%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C  C    LG ++  K    YC T Y+++F + C  C   IE D   +   ++ W  
Sbjct: 216 HFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWCV 273

Query: 65  GCFKCTKCNHSL-VEKPFAAKDERLLCTECY 94
            CF C+ CN  L ++  F   D + +C  CY
Sbjct: 274 SCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 304


>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
           3 [Homo sapiens]
          Length = 341

 Score =  107 bits (268), Expect = 9e-24
 Identities = 65/275 (23%), Positives = 116/275 (42%), Gaps = 11/275 (4%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C        +   +   YC   +  +F+  C  C + I    + +   + +WH G
Sbjct: 41  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPG 98

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKC--FHCKRT-IMPGSRKMEFKGNY 122
           CF+C  C+  L +  F     R LC  C++ E +     + C+R  ++   + + F+ + 
Sbjct: 99  CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDA 158

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLW 182
           +H   F C +C + + T      +   YC+PC +K     C  C++ I    +    + W
Sbjct: 159 YHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQW 217

Query: 183 HKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQD 242
           H E F+C+ C K     +   +    +C   YN L+ + C  CS  I G      +   +
Sbjct: 218 HVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSALN 273

Query: 243 SQWHSECFNCGKCSVSLVGKG-FLTQNKEIFCQKC 276
             W   CF+C  C+  L  K  F+  + +  C++C
Sbjct: 274 KAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRC 308



 Score = 97.8 bits (242), Expect = 9e-21
 Identities = 60/246 (24%), Positives = 98/246 (39%), Gaps = 12/246 (4%)

Query: 34  DRVFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTEC 93
           D + +  C+ C+       + +      +HE CF C +C     E  F   + R  C   
Sbjct: 8   DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 67

Query: 94  YSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVP 153
           +    +  C  C   I+   R ++   N WH  CF CE C   +     +     + C P
Sbjct: 68  FQMLFAPCCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 125

Query: 154 CFEKEFA-----HYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYP 208
           C  +E A     + C  C  VI    + F    +H + F C+ C K+L  E    + +  
Sbjct: 126 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL- 184

Query: 209 FCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQN 268
           +C+ C++ +    C AC +PI G    + +     QWH E F C KC    +G     + 
Sbjct: 185 YCLPCHDKMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKK 240

Query: 269 KEIFCQ 274
              +C+
Sbjct: 241 GLAYCE 246



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 50/188 (26%), Positives = 70/188 (37%), Gaps = 10/188 (5%)

Query: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAH 161
           C  C+    P  R +   G  +HE CFVC  C +P         E   YC   F+  FA 
Sbjct: 15  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 74

Query: 162 YCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANK 221
            C  C + I    I   +  WH  CF C  C  +L +  F+       C  C+N   A  
Sbjct: 75  CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 134

Query: 222 -----CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
                C  C   I      + + F+   +H + FNC  C   L  +    +  E++C  C
Sbjct: 135 LGKYICQRCHLVID----EQPLMFRSDAYHPDHFNCTHCGKELTAEARELKG-ELYCLPC 189

Query: 277 GSGMDTDI 284
              M   I
Sbjct: 190 HDKMGVPI 197



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 3/91 (3%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C  C    LG ++  K    YC T Y+++F + C  C   IE D   +   ++ W  
Sbjct: 221 HFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWCV 278

Query: 65  GCFKCTKCNHSL-VEKPFAAKDERLLCTECY 94
            CF C+ CN  L ++  F   D + +C  CY
Sbjct: 279 SCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 309


>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
           [Homo sapiens]
          Length = 365

 Score =  107 bits (268), Expect = 9e-24
 Identities = 65/275 (23%), Positives = 116/275 (42%), Gaps = 11/275 (4%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C  C        +   +   YC   +  +F+  C  C + I    + +   + +WH G
Sbjct: 65  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPG 122

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKC--FHCKRT-IMPGSRKMEFKGNY 122
           CF+C  C+  L +  F     R LC  C++ E +     + C+R  ++   + + F+ + 
Sbjct: 123 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDA 182

Query: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLW 182
           +H   F C +C + + T      +   YC+PC +K     C  C++ I    +    + W
Sbjct: 183 YHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQW 241

Query: 183 HKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQD 242
           H E F+C+ C K     +   +    +C   YN L+ + C  CS  I G      +   +
Sbjct: 242 HVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSALN 297

Query: 243 SQWHSECFNCGKCSVSLVGKG-FLTQNKEIFCQKC 276
             W   CF+C  C+  L  K  F+  + +  C++C
Sbjct: 298 KAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRC 332



 Score = 97.8 bits (242), Expect = 9e-21
 Identities = 60/246 (24%), Positives = 98/246 (39%), Gaps = 12/246 (4%)

Query: 34  DRVFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTEC 93
           D + +  C+ C+       + +      +HE CF C +C     E  F   + R  C   
Sbjct: 32  DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 91

Query: 94  YSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVP 153
           +    +  C  C   I+   R ++   N WH  CF CE C   +     +     + C P
Sbjct: 92  FQMLFAPCCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 149

Query: 154 CFEKEFA-----HYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYP 208
           C  +E A     + C  C  VI    + F    +H + F C+ C K+L  E    + +  
Sbjct: 150 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL- 208

Query: 209 FCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQN 268
           +C+ C++ +    C AC +PI G    + +     QWH E F C KC    +G     + 
Sbjct: 209 YCLPCHDKMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKK 264

Query: 269 KEIFCQ 274
              +C+
Sbjct: 265 GLAYCE 270



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 50/188 (26%), Positives = 70/188 (37%), Gaps = 10/188 (5%)

Query: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAH 161
           C  C+    P  R +   G  +HE CFVC  C +P         E   YC   F+  FA 
Sbjct: 39  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 98

Query: 162 YCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANK 221
            C  C + I    I   +  WH  CF C  C  +L +  F+       C  C+N   A  
Sbjct: 99  CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 158

Query: 222 -----CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
                C  C   I      + + F+   +H + FNC  C   L  +    +  E++C  C
Sbjct: 159 LGKYICQRCHLVID----EQPLMFRSDAYHPDHFNCTHCGKELTAEARELKG-ELYCLPC 213

Query: 277 GSGMDTDI 284
              M   I
Sbjct: 214 HDKMGVPI 221



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 3/91 (3%)

Query: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
           HF C  C    LG ++  K    YC T Y+++F + C  C   IE D   +   ++ W  
Sbjct: 245 HFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWCV 302

Query: 65  GCFKCTKCNHSL-VEKPFAAKDERLLCTECY 94
            CF C+ CN  L ++  F   D + +C  CY
Sbjct: 303 SCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 333


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score =  106 bits (265), Expect = 2e-23
 Identities = 53/174 (30%), Positives = 76/174 (43%), Gaps = 4/174 (2%)

Query: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAH 161
           C HC   I      +   G  WH   F C  C+  +     + +++  YC  C+E+ FA 
Sbjct: 441 CGHCNNVIR--GPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498

Query: 162 YCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANK 221
            C  C   I    +    Q WH  CF+C+ C+K      F   D  P+C   Y +L++ K
Sbjct: 499 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTK 558

Query: 222 CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQK 275
           C  C  P+    G KFI      WH  CF C  C V+L G+ F ++     C+K
Sbjct: 559 CHGCDFPVE--AGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK 610



 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 48/159 (30%), Positives = 71/159 (44%), Gaps = 7/159 (4%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C YC  SL    +V + ++ YC  CY++ F+  C +C   I  +      +   WH  
Sbjct: 465 FTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQT--WHTT 522

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF C  C        F  +D    C + Y N  S+KC  C   +  G + +E  G+ WH+
Sbjct: 523 CFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHD 582

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCN 164
           TCF+C  C   +  +P  SK+    C     K+ AH  N
Sbjct: 583 TCFICAVCHVNLEGQPFYSKKDRPLC-----KKHAHTIN 616



 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 6/172 (3%)

Query: 41  CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSS 100
           C  C   I      L    R WH   F C  C  SL +  F  +   + C  CY    + 
Sbjct: 441 CGHCNNVIRGPF--LVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498

Query: 101 KCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFA 160
            C  C   IM     M      WH TCFVC  C++P G      ++   YC   +   F+
Sbjct: 499 LCAKCNTKIM--GEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFS 556

Query: 161 HYCNFCKKVITSGG--ITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFC 210
             C+ C   + +G   I      WH  CF+C+ C  +L  + F S+ D P C
Sbjct: 557 TKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608



 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 29/88 (32%), Positives = 42/88 (47%)

Query: 3   TAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHW 62
           T  F C  C        + ++D  PYC   Y  +FS  C  C  P+E+  K +      W
Sbjct: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580

Query: 63  HEGCFKCTKCNHSLVEKPFAAKDERLLC 90
           H+ CF C  C+ +L  +PF +K +R LC
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 16/55 (29%), Positives = 24/55 (43%), Gaps = 4/55 (7%)

Query: 222 CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           C  C+  I G     F+      WH E F C  C  SL    F+ +   ++C++C
Sbjct: 441 CGHCNNVIRG----PFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERC 491


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score =  106 bits (265), Expect = 2e-23
 Identities = 53/174 (30%), Positives = 76/174 (43%), Gaps = 4/174 (2%)

Query: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAH 161
           C HC   I      +   G  WH   F C  C+  +     + +++  YC  C+E+ FA 
Sbjct: 551 CGHCNNVIR--GPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 608

Query: 162 YCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANK 221
            C  C   I    +    Q WH  CF+C+ C+K      F   D  P+C   Y +L++ K
Sbjct: 609 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTK 668

Query: 222 CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQK 275
           C  C  P+    G KFI      WH  CF C  C V+L G+ F ++     C+K
Sbjct: 669 CHGCDFPVE--AGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK 720



 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 48/159 (30%), Positives = 71/159 (44%), Gaps = 7/159 (4%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C YC  SL    +V + ++ YC  CY++ F+  C +C   I  +      +   WH  
Sbjct: 575 FTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQT--WHTT 632

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF C  C        F  +D    C + Y N  S+KC  C   +  G + +E  G+ WH+
Sbjct: 633 CFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHD 692

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCN 164
           TCF+C  C   +  +P  SK+    C     K+ AH  N
Sbjct: 693 TCFICAVCHVNLEGQPFYSKKDRPLC-----KKHAHTIN 726



 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 6/172 (3%)

Query: 41  CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSS 100
           C  C   I      L    R WH   F C  C  SL +  F  +   + C  CY    + 
Sbjct: 551 CGHCNNVIRGPF--LVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 608

Query: 101 KCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFA 160
            C  C   IM     M      WH TCFVC  C++P G      ++   YC   +   F+
Sbjct: 609 LCAKCNTKIM--GEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFS 666

Query: 161 HYCNFCKKVITSGG--ITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFC 210
             C+ C   + +G   I      WH  CF+C+ C  +L  + F S+ D P C
Sbjct: 667 TKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718



 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 29/88 (32%), Positives = 42/88 (47%)

Query: 3   TAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHW 62
           T  F C  C        + ++D  PYC   Y  +FS  C  C  P+E+  K +      W
Sbjct: 631 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 690

Query: 63  HEGCFKCTKCNHSLVEKPFAAKDERLLC 90
           H+ CF C  C+ +L  +PF +K +R LC
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLC 718



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 16/55 (29%), Positives = 24/55 (43%), Gaps = 4/55 (7%)

Query: 222 CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
           C  C+  I G     F+      WH E F C  C  SL    F+ +   ++C++C
Sbjct: 551 CGHCNNVIRG----PFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERC 601


>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
          Length = 487

 Score =  101 bits (252), Expect = 7e-22
 Identities = 53/174 (30%), Positives = 75/174 (43%), Gaps = 4/174 (2%)

Query: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAH 161
           C HC + I      +   G  WH   F C +C+  +     + ++   YC  C+EK FA 
Sbjct: 311 CAHCNQVIR--GPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368

Query: 162 YCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANK 221
            C  C++ I    I+   Q WH  CF+C  C K +    F   D  P+C   Y  L+   
Sbjct: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTI 428

Query: 222 CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQK 275
           C  C  PI    G  F+      WH  CF C  C  SL G+ F ++  +  C+K
Sbjct: 429 CHGCEFPIE--AGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKK 480



 Score = 84.7 bits (208), Expect = 8e-17
 Identities = 49/173 (28%), Positives = 74/173 (42%), Gaps = 8/173 (4%)

Query: 41  CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSS 100
           C  C + I      L    + WH   F C  C +++    F  +   L C  CY    + 
Sbjct: 311 CAHCNQVIRGPF--LVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368

Query: 101 KCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFA 160
           +C  C+R I+     +      WH +CFVC  C +PI       ++   YC   +   F 
Sbjct: 369 ECGRCQRKIL--GEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 426

Query: 161 HYCNFCKKVITSGGITFCDQL---WHKECFLCSGCRKDLCEEQFMSRDDYPFC 210
             C+ C+  I +G + F + L   WH  CF+CS C + L  + F S+ D P C
Sbjct: 427 TICHGCEFPIEAGDM-FLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 44/160 (27%), Positives = 69/160 (43%), Gaps = 7/160 (4%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C +C  ++    +V +  + YC  CY++ F+  C  C++ I  +   +    + WH  
Sbjct: 335 FNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEV--ISALKQTWHVS 392

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF C  C   +    F  +D    C   Y     + C  C+  I  G   +E  G  WH+
Sbjct: 393 CFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHD 452

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNF 165
           TCFVC  C + +  +   SK+    C     K+ AH  NF
Sbjct: 453 TCFVCSVCCESLEGQTFFSKKDKPLC-----KKHAHSVNF 487



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 8/65 (12%)

Query: 216 HLYANK----CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEI 271
           H+ A K    C  C++ I G     F+      WH E FNC  C  ++   GF+ +   +
Sbjct: 301 HIPAGKRTPMCAHCNQVIRG----PFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGAL 356

Query: 272 FCQKC 276
           +C+ C
Sbjct: 357 YCELC 361


>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
          Length = 596

 Score =  101 bits (252), Expect = 7e-22
 Identities = 53/174 (30%), Positives = 75/174 (43%), Gaps = 4/174 (2%)

Query: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAH 161
           C HC + I      +   G  WH   F C +C+  +     + ++   YC  C+EK FA 
Sbjct: 420 CAHCNQVIR--GPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477

Query: 162 YCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANK 221
            C  C++ I    I+   Q WH  CF+C  C K +    F   D  P+C   Y  L+   
Sbjct: 478 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTI 537

Query: 222 CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQK 275
           C  C  PI    G  F+      WH  CF C  C  SL G+ F ++  +  C+K
Sbjct: 538 CHGCEFPIE--AGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKK 589



 Score = 84.7 bits (208), Expect = 8e-17
 Identities = 49/173 (28%), Positives = 74/173 (42%), Gaps = 8/173 (4%)

Query: 41  CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSS 100
           C  C + I      L    + WH   F C  C +++    F  +   L C  CY    + 
Sbjct: 420 CAHCNQVIRGPF--LVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477

Query: 101 KCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFA 160
           +C  C+R I+     +      WH +CFVC  C +PI       ++   YC   +   F 
Sbjct: 478 ECGRCQRKIL--GEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 535

Query: 161 HYCNFCKKVITSGGITFCDQL---WHKECFLCSGCRKDLCEEQFMSRDDYPFC 210
             C+ C+  I +G + F + L   WH  CF+CS C + L  + F S+ D P C
Sbjct: 536 TICHGCEFPIEAGDM-FLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 587



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 44/160 (27%), Positives = 69/160 (43%), Gaps = 7/160 (4%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C +C  ++    +V +  + YC  CY++ F+  C  C++ I  +   +    + WH  
Sbjct: 444 FNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEV--ISALKQTWHVS 501

Query: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
           CF C  C   +    F  +D    C   Y     + C  C+  I  G   +E  G  WH+
Sbjct: 502 CFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHD 561

Query: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNF 165
           TCFVC  C + +  +   SK+    C     K+ AH  NF
Sbjct: 562 TCFVCSVCCESLEGQTFFSKKDKPLC-----KKHAHSVNF 596



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 8/65 (12%)

Query: 216 HLYANK----CVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEI 271
           H+ A K    C  C++ I G     F+      WH E FNC  C  ++   GF+ +   +
Sbjct: 410 HIPAGKRTPMCAHCNQVIRG----PFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGAL 465

Query: 272 FCQKC 276
           +C+ C
Sbjct: 466 YCELC 470


>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
          Length = 746

 Score =  100 bits (250), Expect = 1e-21
 Identities = 66/255 (25%), Positives = 106/255 (41%), Gaps = 20/255 (7%)

Query: 40  YCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECS 99
           +C +C +P + +   L  + +H+H  CF C  C   L +  F  K+   LCT  Y     
Sbjct: 38  HCHKCGEPCKGEV--LRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYG 95

Query: 100 SKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGN-YCVPCF--- 155
           ++C  C   +      +   G  +H  CF C  C++P      ++    +  C  C    
Sbjct: 96  TRCHGCGEFV--EGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPM 153

Query: 156 -----EKEFAHYCNFCKKVITSG-GITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPF 209
                E  F+  C  C + I +G  +   D+ WH  CF C  C K L  E ++S+D  P+
Sbjct: 154 SSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPY 212

Query: 210 CMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLV-GKGFLTQN 268
           C   Y  L+  KC AC + I+G    K +   D  +H  C  C +C+     G+    Q 
Sbjct: 213 CEKDYQGLFGVKCEACHQFITG----KVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG 268

Query: 269 KEIFCQKCGSGMDTD 283
             ++   C     T+
Sbjct: 269 STVWHPDCKQSTKTE 283



 Score = 79.0 bits (193), Expect = 5e-15
 Identities = 56/211 (26%), Positives = 84/211 (39%), Gaps = 23/211 (10%)

Query: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
           F C+ C   L    + +K+    C   Y R++   C  C + +E +      K   +H  
Sbjct: 63  FTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKT--YHPN 120

Query: 66  CFKCTKCNHSLVEKPFAAKDERL---------LCTECYSNE-----CSSKCFHCKRTIMP 111
           CF CT C     ++PF   D            LC +  S+       SS C  C R I  
Sbjct: 121 CFACTIC-----KRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKN 175

Query: 112 GSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVIT 171
           G   +      WH  CF C++C + + T   ISK+   YC   ++  F   C  C + IT
Sbjct: 176 GQALLALD-KQWHLGCFKCKSCGKVL-TGEYISKDGAPYCEKDYQGLFGVKCEACHQFIT 233

Query: 172 SGGITFCDQLWHKECFLCSGCRKDLCEEQFM 202
              +   D+ +H  C  CS C +   E + M
Sbjct: 234 GKVLEAGDKHYHPSCARCSRCNQMFTEGEEM 264


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.497 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,336,498
Number of Sequences: 37866
Number of extensions: 708164
Number of successful extensions: 10081
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 370
Number of HSP's successfully gapped in prelim test: 504
Number of HSP's that attempted gapping in prelim test: 2540
Number of HSP's gapped (non-prelim): 3410
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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