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Search of human proteins with 30410720
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30410720 exocyst complex component 1 isoform 1 [Homo
sapiens]
(894 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67944634 exocyst complex component 1 isoform 1 [Homo sapiens] 1762 0.0
gi|30410720 exocyst complex component 1 isoform 1 [Homo sapiens] 1762 0.0
gi|30410716 exocyst complex component 1 isoform 2 [Homo sapiens] 1722 0.0
gi|21426793 amisyn [Homo sapiens] 86 1e-16
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 54 5e-07
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 42 0.002
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 42 0.002
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 42 0.002
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 42 0.002
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 42 0.003
gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo s... 42 0.003
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 42 0.003
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 41 0.006
gi|118498362 kinectin 1 isoform b [Homo sapiens] 40 0.013
gi|33188443 microfilament and actin filament cross-linker protei... 40 0.013
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 40 0.013
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 40 0.013
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 39 0.022
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 39 0.022
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 39 0.022
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 39 0.022
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 39 0.022
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 39 0.022
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 39 0.022
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 39 0.022
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 39 0.022
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 39 0.028
gi|38044112 restin isoform b [Homo sapiens] 39 0.028
gi|4506751 restin isoform a [Homo sapiens] 39 0.028
gi|71061468 centromere protein E [Homo sapiens] 39 0.028
>gi|67944634 exocyst complex component 1 isoform 1 [Homo sapiens]
Length = 894
Score = 1762 bits (4563), Expect = 0.0
Identities = 894/894 (100%), Positives = 894/894 (100%)
Query: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK
Sbjct: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
Query: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ
Sbjct: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
Query: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY
Sbjct: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
Query: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE
Sbjct: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
Query: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG
Sbjct: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
Query: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH
Sbjct: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
Query: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER
Sbjct: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
Query: 421 EIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQ 480
EIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQ
Sbjct: 421 EIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQ 480
Query: 481 SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ 540
SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ
Sbjct: 481 SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ 540
Query: 541 QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL 600
QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL
Sbjct: 541 QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL 600
Query: 601 GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE 660
GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE
Sbjct: 601 GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE 660
Query: 661 VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES 720
VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES
Sbjct: 661 VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES 720
Query: 721 QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH 780
QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH
Sbjct: 721 QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH 780
Query: 781 FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE 840
FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE
Sbjct: 781 FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE 840
Query: 841 NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 894
NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH
Sbjct: 841 NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 894
>gi|30410720 exocyst complex component 1 isoform 1 [Homo sapiens]
Length = 894
Score = 1762 bits (4563), Expect = 0.0
Identities = 894/894 (100%), Positives = 894/894 (100%)
Query: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK
Sbjct: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
Query: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ
Sbjct: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
Query: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY
Sbjct: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
Query: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE
Sbjct: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
Query: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG
Sbjct: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
Query: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH
Sbjct: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
Query: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER
Sbjct: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
Query: 421 EIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQ 480
EIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQ
Sbjct: 421 EIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQ 480
Query: 481 SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ 540
SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ
Sbjct: 481 SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ 540
Query: 541 QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL 600
QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL
Sbjct: 541 QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL 600
Query: 601 GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE 660
GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE
Sbjct: 601 GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE 660
Query: 661 VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES 720
VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES
Sbjct: 661 VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES 720
Query: 721 QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH 780
QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH
Sbjct: 721 QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH 780
Query: 781 FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE 840
FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE
Sbjct: 781 FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE 840
Query: 841 NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 894
NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH
Sbjct: 841 NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 894
>gi|30410716 exocyst complex component 1 isoform 2 [Homo sapiens]
Length = 879
Score = 1722 bits (4461), Expect = 0.0
Identities = 878/894 (98%), Positives = 878/894 (98%), Gaps = 15/894 (1%)
Query: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK
Sbjct: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
Query: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ
Sbjct: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
Query: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY
Sbjct: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
Query: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE
Sbjct: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
Query: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG
Sbjct: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
Query: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH
Sbjct: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
Query: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER
Sbjct: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
Query: 421 EIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQ 480
EIKDFFEVAKIKMTGTTKESKKF LHGSSGKLTGSTSSLNKLSVQ
Sbjct: 421 EIKDFFEVAKIKMTGTTKESKKF---------------GLHGSSGKLTGSTSSLNKLSVQ 465
Query: 481 SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ 540
SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ
Sbjct: 466 SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ 525
Query: 541 QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL 600
QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL
Sbjct: 526 QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL 585
Query: 601 GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE 660
GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE
Sbjct: 586 GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE 645
Query: 661 VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES 720
VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES
Sbjct: 646 VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES 705
Query: 721 QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH 780
QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH
Sbjct: 706 QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH 765
Query: 781 FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE 840
FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE
Sbjct: 766 FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE 825
Query: 841 NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 894
NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH
Sbjct: 826 NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 879
>gi|21426793 amisyn [Homo sapiens]
Length = 210
Score = 86.3 bits (212), Expect = 1e-16
Identities = 65/200 (32%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query: 5 KHALQRDIFTPNDERLLSIVNVCKAGKKKKN-----------CFLCATVTTERPVQVKVV 53
K A+ ++IF P DER+L V V + KKK ++C +VT ++P Q +
Sbjct: 4 KSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSVTNKKPTQASIT 63
Query: 54 KVKKSDKGDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIY-KWVASSTAEKNAFI 112
KVK+ + + R+ W L L V+ D ++ EFDL FE + +WVAS+ +EK F
Sbjct: 64 KVKQFEGSTSFVRRSQWMLEQLRQVNGIDPNGDSAEFDLLFENAFDQWVASTASEKCTFF 123
Query: 113 SCIWKLNQRYLR-KKIDFVNVSSQLL-EESVPSGENQSVTGGDEEVVDEYQELNAREEQD 170
+ QRYL +K +F+N S+++ S+ SVT V Q LN R E+
Sbjct: 124 QILHHTCQRYLTDRKPEFINCQSKIMGGNSILHSAADSVTSA---VQKASQALNERGER- 179
Query: 171 IEIMMEGCEYAISNAEAFAE 190
+ E E ++A+ FAE
Sbjct: 180 LGRAEEKTEDLKNSAQQFAE 199
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 54.3 bits (129), Expect = 5e-07
Identities = 147/719 (20%), Positives = 287/719 (39%), Gaps = 91/719 (12%)
Query: 154 EEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQ 213
++ V + L R ++ I+ E C S EA E+L LQ L+ I+ + +EK
Sbjct: 285 QQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELE--KIKDLHMAEKT 342
Query: 214 VNILMKLLDEALKEVDQIE-----LKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVK 268
L+ L +A ++Q+E + + +M ++++ + ++I++ I T +
Sbjct: 343 K--LITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEE 400
Query: 269 LLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMNVALRPGHDLLLA 328
L + E K A +E + A S + A L M+ ++ +
Sbjct: 401 LREQKE---------KSERAAFEELEKALSTA-QKTEEARRKLKAEMDEQIKT-----IE 445
Query: 329 VKQQQQRFSDLRELFARRLASHLNNVFVQQGHDQSSTLAQ-HSVELTLPNHHPFHRDLLR 387
+++R S +EL R+ + +V + +Q + L + H EL + R
Sbjct: 446 KTSEEERISLQQEL--SRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTR 503
Query: 388 YAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYEREIKDFFEVAKIKMTGT---TKESKKFA 444
+ E +K L K+ +YL E+E ++ + ++++ T+ K
Sbjct: 504 EREFQEQMKVA-------LEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLR 556
Query: 445 TLPRKESAVKQETESLHGSSGKLTGSTSSLNK-LSVQSSGNRRSQSSSLLDMGNMSASDL 503
L ++ + L S K + +K L+V + + + M ++L
Sbjct: 557 DLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTEL 616
Query: 504 -------DVADRTKFDKIFEQVLSELEPL---CLAEQDFISKFFKLQQHQSMPGTMAEAE 553
D K + +Q +E+E L C E++ + K ++ A E
Sbjct: 617 ESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEII-------FQAHIE 669
Query: 554 DLDGGTLSRQHNCGTPLP-VSSEKDMIRQMMIKIFRCIEPELNNLIALGDKIDSFNSLYM 612
+++ TL + T L +SSE + +K +E EL+ L DK+ M
Sbjct: 670 EMNEKTLEKLDVKQTELESLSSELSEV----LKARHKLEEELSVLKDQTDKMKQELEAKM 725
Query: 613 LVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGIL 672
+ +HH Q VD + + V+++R +K + +QI Q+E + + ++ K
Sbjct: 726 DEQKNHH---QQQVD------SIIKEHEVSIQRT-EKALKDQINQLE-LLLKERDK---- 770
Query: 673 PFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANESQKTPRDVVMMEN 732
+ E + E+ K +E G+L +A KL VF + + +E K + +
Sbjct: 771 -HLKEHQAHVENLEADIKRSE--GELQQASAKL--DVFQSYQSATHEQTKAYEEQLAQLQ 825
Query: 733 FHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIY--SLGQPLEKLNHFFEG------ 784
+ R+ ++ AE + K+ L ++ I L Q LEK N E
Sbjct: 826 QKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLT 885
Query: 785 --VEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDK-HLCEEE 840
E+++ G +E+E + Q+ K+ + ++E KE++ L K D H+ EE
Sbjct: 886 QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEE 944
Score = 31.2 bits (69), Expect = 4.5
Identities = 37/159 (23%), Positives = 77/159 (48%), Gaps = 16/159 (10%)
Query: 137 LEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEK-LSRE 195
++E + + E S +EE + QEL+ +++ +++M + E I+ + EK L+R+
Sbjct: 437 MDEQIKTIEKTS----EEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 492
Query: 196 LQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISES 255
Q L + + E++ MK+ AL++ LK+S +E +S+ ++++
Sbjct: 493 EQEL----TKKLQTREREFQEQMKV---ALEKSQSEYLKISQEKEQQESL--ALEELELQ 543
Query: 256 NHLIHLSNTNNVK-LLSEIE-FLVNHMDLAKGHIKALQE 292
I + N ++ L E E + ++L K+LQE
Sbjct: 544 KKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQE 582
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 42.4 bits (98), Expect = 0.002
Identities = 67/320 (20%), Positives = 143/320 (44%), Gaps = 53/320 (16%)
Query: 81 KDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEES 140
K +KE + + E++ +W S E+ A + K ++ ++ ++ + +EE
Sbjct: 108 KAKLKELEKHKIQLEQVQEW-KSKMQEQQADLQRRLKEARKEAKEALE---AKERYMEEM 163
Query: 141 VPSGENQSVTGGDEEVVDE-----YQELNAREEQ------DIEIMMEGCEYAISNAEAFA 189
+ + + D+E+ +E QE+ A +E+ D+EI+ E S+ A +
Sbjct: 164 ADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASS 223
Query: 190 EKLSR----ELQVLDG-ANIQSIMASEKQVNI-LMKLLDEALKEVD-------QIELKLS 236
+L + ++ D ++ + +SEKQ ++ L KL+++ +E++ +++ +LS
Sbjct: 224 YQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 283
Query: 237 SYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLA 296
E + +KEQ+D + ++ + N+ L E V + G ++A+ E
Sbjct: 284 QAESTIDELKEQVDAALGAEEMVEMLTDRNLNL----EEKVRELRETVGDLEAMNE---- 335
Query: 297 SSRGIEACTNAADALLQCMNVALRPGHDLLLA-VKQQQQRFSDLRELFA---------RR 346
E NA + L+ LR D+ A V++ Q+R +E A R+
Sbjct: 336 --MNDELQENARETELE-----LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQ 388
Query: 347 LASHLNNVFVQQGHDQSSTL 366
L +HL +V + + Q +++
Sbjct: 389 LTAHLQDVNRELTNQQEASV 408
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 42.4 bits (98), Expect = 0.002
Identities = 67/320 (20%), Positives = 143/320 (44%), Gaps = 53/320 (16%)
Query: 81 KDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEES 140
K +KE + + E++ +W S E+ A + K ++ ++ ++ + +EE
Sbjct: 222 KAKLKELEKHKIQLEQVQEW-KSKMQEQQADLQRRLKEARKEAKEALE---AKERYMEEM 277
Query: 141 VPSGENQSVTGGDEEVVDE-----YQELNAREEQ------DIEIMMEGCEYAISNAEAFA 189
+ + + D+E+ +E QE+ A +E+ D+EI+ E S+ A +
Sbjct: 278 ADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASS 337
Query: 190 EKLSR----ELQVLDG-ANIQSIMASEKQVNI-LMKLLDEALKEVD-------QIELKLS 236
+L + ++ D ++ + +SEKQ ++ L KL+++ +E++ +++ +LS
Sbjct: 338 YQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 397
Query: 237 SYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLA 296
E + +KEQ+D + ++ + N+ L E V + G ++A+ E
Sbjct: 398 QAESTIDELKEQVDAALGAEEMVEMLTDRNLNL----EEKVRELRETVGDLEAMNE---- 449
Query: 297 SSRGIEACTNAADALLQCMNVALRPGHDLLLA-VKQQQQRFSDLRELFA---------RR 346
E NA + L+ LR D+ A V++ Q+R +E A R+
Sbjct: 450 --MNDELQENARETELE-----LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQ 502
Query: 347 LASHLNNVFVQQGHDQSSTL 366
L +HL +V + + Q +++
Sbjct: 503 LTAHLQDVNRELTNQQEASV 522
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 42.4 bits (98), Expect = 0.002
Identities = 67/320 (20%), Positives = 143/320 (44%), Gaps = 53/320 (16%)
Query: 81 KDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEES 140
K +KE + + E++ +W S E+ A + K ++ ++ ++ + +EE
Sbjct: 108 KAKLKELEKHKIQLEQVQEW-KSKMQEQQADLQRRLKEARKEAKEALE---AKERYMEEM 163
Query: 141 VPSGENQSVTGGDEEVVDE-----YQELNAREEQ------DIEIMMEGCEYAISNAEAFA 189
+ + + D+E+ +E QE+ A +E+ D+EI+ E S+ A +
Sbjct: 164 ADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASS 223
Query: 190 EKLSR----ELQVLDG-ANIQSIMASEKQVNI-LMKLLDEALKEVD-------QIELKLS 236
+L + ++ D ++ + +SEKQ ++ L KL+++ +E++ +++ +LS
Sbjct: 224 YQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 283
Query: 237 SYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLA 296
E + +KEQ+D + ++ + N+ L E V + G ++A+ E
Sbjct: 284 QAESTIDELKEQVDAALGAEEMVEMLTDRNLNL----EEKVRELRETVGDLEAMNE---- 335
Query: 297 SSRGIEACTNAADALLQCMNVALRPGHDLLLA-VKQQQQRFSDLRELFA---------RR 346
E NA + L+ LR D+ A V++ Q+R +E A R+
Sbjct: 336 --MNDELQENARETELE-----LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQ 388
Query: 347 LASHLNNVFVQQGHDQSSTL 366
L +HL +V + + Q +++
Sbjct: 389 LTAHLQDVNRELTNQQEASV 408
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 42.4 bits (98), Expect = 0.002
Identities = 67/320 (20%), Positives = 143/320 (44%), Gaps = 53/320 (16%)
Query: 81 KDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEES 140
K +KE + + E++ +W S E+ A + K ++ ++ ++ + +EE
Sbjct: 242 KAKLKELEKHKIQLEQVQEW-KSKMQEQQADLQRRLKEARKEAKEALE---AKERYMEEM 297
Query: 141 VPSGENQSVTGGDEEVVDE-----YQELNAREEQ------DIEIMMEGCEYAISNAEAFA 189
+ + + D+E+ +E QE+ A +E+ D+EI+ E S+ A +
Sbjct: 298 ADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASS 357
Query: 190 EKLSR----ELQVLDG-ANIQSIMASEKQVNI-LMKLLDEALKEVD-------QIELKLS 236
+L + ++ D ++ + +SEKQ ++ L KL+++ +E++ +++ +LS
Sbjct: 358 YQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 417
Query: 237 SYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLA 296
E + +KEQ+D + ++ + N+ L E V + G ++A+ E
Sbjct: 418 QAESTIDELKEQVDAALGAEEMVEMLTDRNLNL----EEKVRELRETVGDLEAMNE---- 469
Query: 297 SSRGIEACTNAADALLQCMNVALRPGHDLLLA-VKQQQQRFSDLRELFA---------RR 346
E NA + L+ LR D+ A V++ Q+R +E A R+
Sbjct: 470 --MNDELQENARETELE-----LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQ 522
Query: 347 LASHLNNVFVQQGHDQSSTL 366
L +HL +V + + Q +++
Sbjct: 523 LTAHLQDVNRELTNQQEASV 542
>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
sapiens]
Length = 1719
Score = 42.0 bits (97), Expect = 0.003
Identities = 59/287 (20%), Positives = 125/287 (43%), Gaps = 43/287 (14%)
Query: 28 KAGKKKKNCFLCATVTTERPVQVKVVKVKKSDKGDFYKRQIA-----WALRDLAVVDAKD 82
K +KK+ F ++ + +K K + D +Q+A L+D ++
Sbjct: 690 KTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 749
Query: 83 AIKENPEFDLHFEKIYKWVASSTAEKNAFISC-IWKLNQRYLRKKIDFVNVSSQLLEESV 141
+ E EF+ F++ Y+ E+N ++ + KL Y + +++ +Q LEE V
Sbjct: 750 SQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLY-----ENLSIHNQQLEEEV 804
Query: 142 P--SGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVL 199
+ + +SV + ++ + Q ++ +E+D A +A A K++ EL+ L
Sbjct: 805 KDLADKKESVAHWEAQITEIIQWVS--DEKD----------ARGYLQALASKMTEELEAL 852
Query: 200 DGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLI 259
+++ + LD + + +++ L + Q+++E+++++ SN +
Sbjct: 853 RNSSLGTRATDMPWKMRRFAKLDMSARL--ELQSALDAEIRAKQAIQEELNKVKASNIIT 910
Query: 260 HL----SNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIE 302
S N++LLSEIE L+ + +L S +GIE
Sbjct: 911 ECKLKDSEKKNLELLSEIEQLIKDTE------------ELRSEKGIE 945
Score = 33.9 bits (76), Expect = 0.69
Identities = 68/334 (20%), Positives = 128/334 (38%), Gaps = 42/334 (12%)
Query: 183 SNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEML 242
S+ E E+ + Q LD A + I A EKQ+ L + ++ KE+ Q +L + + L
Sbjct: 507 SHLEQQLEEANAVRQELDDA-FRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKEL 565
Query: 243 QSV----KEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASS 298
+ K M + E N + +T KL + +DL +++L++ +
Sbjct: 566 KDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTE 625
Query: 299 RGIEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQ 358
R L + L A + ++ + E ++++L + L + +Q
Sbjct: 626 RA---------------KKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQ 670
Query: 359 -GHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSR- 416
+ +H E+T DL + + E + K EG+ N + L +
Sbjct: 671 ISYSPGVCSIEHQQEIT-----KLKTDLEKKSIFYE----EELSKREGIHANEIKNLKKE 721
Query: 417 LYERE-----IKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETES----LHGSSGKL 467
L++ E + + K K+ T +ES+ + ES KQ+ E L + KL
Sbjct: 722 LHDSEGQQLALNKEIMILKDKLEKTRRESQ--SEREEFESEFKQQYEREKVLLTEENKKL 779
Query: 468 TGSTSSLNKLSVQSSGNRRSQSSSLLDMGNMSAS 501
T L L S + + + D+ + S
Sbjct: 780 TSELDKLTTLYENLSIHNQQLEEEVKDLADKKES 813
>gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo
sapiens]
Length = 1638
Score = 42.0 bits (97), Expect = 0.003
Identities = 59/287 (20%), Positives = 125/287 (43%), Gaps = 43/287 (14%)
Query: 28 KAGKKKKNCFLCATVTTERPVQVKVVKVKKSDKGDFYKRQIA-----WALRDLAVVDAKD 82
K +KK+ F ++ + +K K + D +Q+A L+D ++
Sbjct: 609 KTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 668
Query: 83 AIKENPEFDLHFEKIYKWVASSTAEKNAFISC-IWKLNQRYLRKKIDFVNVSSQLLEESV 141
+ E EF+ F++ Y+ E+N ++ + KL Y + +++ +Q LEE V
Sbjct: 669 SQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLY-----ENLSIHNQQLEEEV 723
Query: 142 P--SGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVL 199
+ + +SV + ++ + Q ++ +E+D A +A A K++ EL+ L
Sbjct: 724 KDLADKKESVAHWEAQITEIIQWVS--DEKD----------ARGYLQALASKMTEELEAL 771
Query: 200 DGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLI 259
+++ + LD + + +++ L + Q+++E+++++ SN +
Sbjct: 772 RNSSLGTRATDMPWKMRRFAKLDMSARL--ELQSALDAEIRAKQAIQEELNKVKASNIIT 829
Query: 260 HL----SNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIE 302
S N++LLSEIE L+ + +L S +GIE
Sbjct: 830 ECKLKDSEKKNLELLSEIEQLIKDTE------------ELRSEKGIE 864
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 41.6 bits (96), Expect = 0.003
Identities = 54/265 (20%), Positives = 113/265 (42%), Gaps = 32/265 (12%)
Query: 133 SSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKL 192
S QL +E V Q G E+ +D+Y E ++ +E+ E ++AEA L
Sbjct: 36 SKQLEDELVSL---QKKLKGTEDELDKYSEALKDAQEKLEL----AEKKATDAEADVASL 88
Query: 193 SRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMD-- 250
+R +Q+++ + + +++++ ++ L+EA K D+ E + E Q +E+M+
Sbjct: 89 NRRIQLVE----EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQ 144
Query: 251 --QISESNHLIHLSNTNN-------VKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGI 301
Q+ E+ H+ ++ V + S++E +L++G L+E + +
Sbjct: 145 EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNL 204
Query: 302 EACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGHD 361
++ A+ Q ++ + V + + ++ R FA R + L ++ D
Sbjct: 205 KSLEAQAEKYSQ-----KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL-----EKSID 254
Query: 362 QSSTLAQHSVELTLPNHHPFHRDLL 386
H+ E L H + LL
Sbjct: 255 DLEEKVAHAKEENLSMHQMLDQTLL 279
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 40.8 bits (94), Expect = 0.006
Identities = 39/171 (22%), Positives = 81/171 (47%), Gaps = 22/171 (12%)
Query: 133 SSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKL 192
S QL +E V Q G E+ +D+Y E ++ +E+ E ++AEA L
Sbjct: 36 SKQLEDELVSL---QKKLKGTEDELDKYSEALKDAQEKLEL----AEKKATDAEADVASL 88
Query: 193 SRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMD-- 250
+R +Q+++ + + +++++ ++ L+EA K D+ E + E Q +E+M+
Sbjct: 89 NRRIQLVE----EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQ 144
Query: 251 --QISESNHLIHLSNTNN-------VKLLSEIEFLVNHMDLAKGHIKALQE 292
Q+ E+ H+ ++ V + S++E +L++G L+E
Sbjct: 145 EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEE 195
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 39.7 bits (91), Expect = 0.013
Identities = 134/694 (19%), Positives = 262/694 (37%), Gaps = 112/694 (16%)
Query: 211 EKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIH--LSNTNNV- 267
EK+ N+ + + +E Q+++K E +++ ++ + + N ++ +SNT N
Sbjct: 384 EKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEA---EIAHLKQENGILRDAVSNTTNQL 440
Query: 268 ---------KLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMNVA 318
KL + LVN + G LQ+ ++ +A T
Sbjct: 441 ESKQSAELNKLRQDYARLVNELTEKTGK---LQQEEVQKKNAEQAATQ------------ 485
Query: 319 LRPGHDLLLAVKQQQQRFSDLRELFARRLASH------LNNVFVQQGHDQSSTLAQHSVE 372
L + +++ ++R+ +++ +R A H L + FV + ++ S ++ +
Sbjct: 486 ------LKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSK--LT 537
Query: 373 LTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSR--LYEREIKDFFEVAK 430
TL + + L++ LME + K E L D L + + +I+ F
Sbjct: 538 DTLVSKQQLEQRLMQ---LME-SEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIA 593
Query: 431 IKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSS 490
+ + + + + K+ +KQ +SL +LT L + + +++
Sbjct: 594 AQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQ-NMNFLLKAEVQ 652
Query: 491 SLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQQHQSMPGTMA 550
L + N A A + +K+ + V + + + L E+ QH+ + M
Sbjct: 653 KLQALANEQA-----AAAHELEKMQQSVYVKDDKIRLLEEQL--------QHE-ISNKME 698
Query: 551 E---AEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKI------FRCIEPEL-NNLIAL 600
E D + S T + KD++ QM I + +E L LI +
Sbjct: 699 EFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQV 758
Query: 601 GDKIDSFNSL----YMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISN--Q 654
K + N++ L K + QN D SF S L L V D I + +
Sbjct: 759 ATKEEELNAIRTENSSLTKEVQDLKAKQN-DQVSFAS--LVEELKKVIHEKDGKIKSVEE 815
Query: 655 IRQMEEVKISKKSKVGILPFVAEFEEFAGLAE------SIFKNAERRGDLDKAYT----- 703
+ + E +K++ K K L ++ +E L + + K + D A T
Sbjct: 816 LLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQ 875
Query: 704 ---KLIRGVFVNVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYT 760
+ + +V++VA + K E + ++ LEA KE + +
Sbjct: 876 DLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKEN-ELKRLEAMLKERESDLS 934
Query: 761 DHLQSYVIYSLGQPLEKLNHFFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKE 820
Q L Q ++ N F+ ++ Q ++ S+ +EL KVI E KE
Sbjct: 935 SKTQ------LLQDVQDENKLFKSQIEQLKQQNYQQASSFP---PHEELLKVISERE-KE 984
Query: 821 VK---KGLDNLYKKVDKHLCEEENLLQVVWHSMQ 851
+ LD+L V+ + +L + W +M+
Sbjct: 985 ISGLWNELDSLKDAVEHQRKKNNDLREKNWEAME 1018
Score = 31.6 bits (70), Expect = 3.4
Identities = 27/132 (20%), Positives = 64/132 (48%), Gaps = 10/132 (7%)
Query: 169 QDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEV 228
+ +E ++E ++N E + LS +V + N+ + E+Q+N + +L+E K++
Sbjct: 811 KSVEELLEAELLKVANKEKTVQ-LSITSKVQELQNL--LKGKEEQMNTMKAVLEEKEKDL 867
Query: 229 DQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIK 288
L +E +S+K + ++++ N L ++ E+E ++ + ++
Sbjct: 868 ANTGKWLQDLQEENESLKAHVQEVAQHN----LKEASSASQFEELEIVLKEKENELKRLE 923
Query: 289 AL---QEGDLAS 297
A+ +E DL+S
Sbjct: 924 AMLKERESDLSS 935
Score = 31.2 bits (69), Expect = 4.5
Identities = 58/282 (20%), Positives = 119/282 (42%), Gaps = 51/282 (18%)
Query: 17 DERLLSIVNVCKAG-----KKKKNCFLCATVTTERPVQVKVVKVKKSDKGDFYKRQIAWA 71
DE+L ++ + + G K++ T + +V+ +K K++D+ F A
Sbjct: 741 DEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSF-----ASL 795
Query: 72 LRDLA-VVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLN--QRYLRKKID 128
+ +L V+ KD ++ E L E + + EK +S K+ Q L+ K +
Sbjct: 796 VEELKKVIHEKDGKIKSVEELLEAELL----KVANKEKTVQLSITSKVQELQNLLKGKEE 851
Query: 129 FVNVSSQLLEESVPS------------GENQSVTGGDEEVVDEY--QELNAREEQDIEIM 174
+N +LEE EN+S+ +EV + +A + +++EI+
Sbjct: 852 QMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIV 911
Query: 175 MEGCEYAISNAEAFAEK----LSRELQVLDGAN-----IQSIMASEKQVNI--------- 216
++ E + EA ++ LS + Q+L +S + KQ N
Sbjct: 912 LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPH 971
Query: 217 --LMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESN 256
L+K++ E KE+ + +L S ++ ++ +++ + + E N
Sbjct: 972 EELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKN 1013
>gi|33188443 microfilament and actin filament cross-linker protein
isoform b [Homo sapiens]
Length = 5938
Score = 39.7 bits (91), Expect = 0.013
Identities = 73/340 (21%), Positives = 135/340 (39%), Gaps = 65/340 (19%)
Query: 227 EVDQIELKLSSYEEMLQSVKEQMDQISE---------SNHLIHLS---NTNNVKLLSE-- 272
+VD + L L YE++ Q + E+ Q+ S H LS N ++LL+E
Sbjct: 1955 DVDSLNLCLQQYEDLKQPMAERKAQLDALAFDIQFFISEHAQDLSPQQNRQMLRLLNELQ 2014
Query: 273 ------IEFLVNHMDLAKGHIKALQEGDLASS--RGIEACTNAADALLQCMNVALR--PG 322
+E +D +GH++ +++ L + + C + L + A R G
Sbjct: 2015 RSFQDILEQTAAQVDALQGHLQQMEQEALVKTLQKQQNTCHQQLEDLCSWVGQAERALAG 2074
Query: 323 H------DLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGHDQSSTLAQHSVELTLP 376
H L A+++ Q DL++ R S F D + ++ +L+ P
Sbjct: 2075 HQGRTTQQDLSALQKNQSDLKDLQDDIQNRATS-----FATVVKDIEGFMEENQTKLS-P 2128
Query: 377 NHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYEREIKDFFEVAKIKMTGT 436
R+ L AK +YE L + +R+ ++E+++ A + T
Sbjct: 2129 RELTALREKLHQAK----------EQYEALQEE-----TRVAQKELEEAVTSALQQETEK 2173
Query: 437 TKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDMG 496
+K +K+ A +K A+ S+ S G+L + + +LS S L+ G
Sbjct: 2174 SKAAKELAENKKKIDALLDWVTSVGSSGGQLLTNLPGMEQLSGAS-----------LEKG 2222
Query: 497 NMSASDLDVADR---TKFDKIFEQVLSELEPLCLAEQDFI 533
+ +D + K DK E + + + L +Q+FI
Sbjct: 2223 ALDTTDGYMGVNQAPEKLDKQCEMMKARHQELLSQQQNFI 2262
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 39.7 bits (91), Expect = 0.013
Identities = 64/337 (18%), Positives = 136/337 (40%), Gaps = 60/337 (17%)
Query: 155 EVVDEYQELNAREEQD---IEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASE 211
E + + + A +EQ ++++ C+ + ++ + A+ + + Q ++ +Q+ ++
Sbjct: 4000 EAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQ 4059
Query: 212 --KQVNILMKLLDEALKEVDQ---------IELKLSSYEEMLQSVKEQMDQISES----N 256
+++ L L L++ DQ EL+L+ + M+ VK+ + ++ N
Sbjct: 4060 GWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVN 4119
Query: 257 HLIHLSNTNNVKLLSEIEFLVNHM-----DLAK--GHIKALQEGDLASSRGIEACTNAAD 309
+I N K S +NH+ DL + ++ +E DL +R C N +
Sbjct: 4120 TIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVE 4179
Query: 310 ALLQCMN---------------VALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLN-- 352
L+ V L L LA+++++ DL++ +++ HLN
Sbjct: 4180 VFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQ-KQKMIEHLNLD 4238
Query: 353 --------NVFVQQGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYE 404
++Q Q L + +++++ N + R+ +LMEW + E
Sbjct: 4239 DKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAE 4298
Query: 405 GLTKN---------YMDYLSRLYEREIKDFFEVAKIK 432
L ++ MD+L+ E E K + IK
Sbjct: 4299 ALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIK 4335
Score = 32.3 bits (72), Expect = 2.0
Identities = 55/278 (19%), Positives = 109/278 (39%), Gaps = 50/278 (17%)
Query: 90 FDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEESVPSGENQSV 149
F +FE + W+ E NA + ++ + + K+ + S+L S+
Sbjct: 1458 FGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKL----------SSI 1507
Query: 150 TGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMA 209
G +EE Q + E I+ ++ + E+L Q L+G + +
Sbjct: 1508 VGLEEEAQSFAQFVTTGESARIKA-------KLTQIRRYGEELREHAQCLEGTILGHLSQ 1560
Query: 210 SEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKL 269
+K +E L+++ QSV E D+++ + S T K+
Sbjct: 1561 QQK--------FEENLRKIQ-------------QSVSEFEDKLAVPIKICS-SATETYKV 1598
Query: 270 LSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMNVALRPGHDLLLAV 329
L E HMDL + +++L A S N D+ +Q + D+L
Sbjct: 1599 LQE------HMDLCQA-LESLSSAITAFSASARKVVN-RDSCVQEAAALQQQYEDILRRA 1650
Query: 330 KQQQQRFSDLRELFARRLASHLNN--VFVQQGHDQSST 365
K++Q +L + +RL L++ ++++G ++S+
Sbjct: 1651 KERQTALENLLAHW-QRLEKELSSFLTWLERGEAKASS 1687
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 39.7 bits (91), Expect = 0.013
Identities = 64/337 (18%), Positives = 136/337 (40%), Gaps = 60/337 (17%)
Query: 155 EVVDEYQELNAREEQD---IEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASE 211
E + + + A +EQ ++++ C+ + ++ + A+ + + Q ++ +Q+ ++
Sbjct: 4071 EAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQ 4130
Query: 212 --KQVNILMKLLDEALKEVDQ---------IELKLSSYEEMLQSVKEQMDQISES----N 256
+++ L L L++ DQ EL+L+ + M+ VK+ + ++ N
Sbjct: 4131 GWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVN 4190
Query: 257 HLIHLSNTNNVKLLSEIEFLVNHM-----DLAK--GHIKALQEGDLASSRGIEACTNAAD 309
+I N K S +NH+ DL + ++ +E DL +R C N +
Sbjct: 4191 TIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVE 4250
Query: 310 ALLQCMN---------------VALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLN-- 352
L+ V L L LA+++++ DL++ +++ HLN
Sbjct: 4251 VFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQ-KQKMIEHLNLD 4309
Query: 353 --------NVFVQQGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYE 404
++Q Q L + +++++ N + R+ +LMEW + E
Sbjct: 4310 DKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAE 4369
Query: 405 GLTKN---------YMDYLSRLYEREIKDFFEVAKIK 432
L ++ MD+L+ E E K + IK
Sbjct: 4370 ALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIK 4406
Score = 33.5 bits (75), Expect = 0.91
Identities = 104/543 (19%), Positives = 218/543 (40%), Gaps = 87/543 (16%)
Query: 116 WKLNQRYLRK-KIDFVNVSSQL-LEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEI 173
W+ Q L + + F NV ++L L E ++ + +E+V + + R ++I++
Sbjct: 3579 WQAYQHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQL 3638
Query: 174 --MMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEK------------QVNILMK 219
M + E + + E +R ++LD +++ S M + QV +K
Sbjct: 3639 HQMKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIK 3698
Query: 220 LLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNH 279
L+E ++ +++ E LSSY + S + + + + + K L +E L+
Sbjct: 3699 FLEEEIQSLEESESSLSSYSDWYGSTHKNFKNV--ATKIDKVDTVMMGKKLKTLEVLLK- 3755
Query: 280 MDLAKGH-------------IKALQEGDLASSRGIEACTNAADALLQCMNVALRPGHDLL 326
D+ KGH +K L+EG+ R + + + L + + +R H L
Sbjct: 3756 -DMEKGHSLLKSAREKGERAVKYLEEGEAERLR--KEIHDHMEQLKE-LTSTVRKEHMTL 3811
Query: 327 LAVKQQQQRFSDLRELFARRLASHLNNVFVQQG-----HDQSSTLAQH-SVELTLPNHHP 380
+ FSD + + +A + + V + +++ + L+++ S++ T+ +H P
Sbjct: 3812 EKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEP 3871
Query: 381 FHRDLLRYAK-LMEWLK-----------STDY------GK-----YEGLTKNYMDYLSRL 417
+ + + L+E ++ +DY GK E K++ DY S L
Sbjct: 3872 SVKSVREKGEALLELVQDVTLKDKIDQLQSDYQDLCSIGKEHVFSLEAKVKDHEDYNSEL 3931
Query: 418 YEREIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKL 477
E E K +++ + E+ T+ ++ + K E + G +L + L
Sbjct: 3932 QEVE-KWLLQMSGRLVAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLNNLQMKGDTL 3990
Query: 478 SVQSSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFF 537
Q + + +++ + D A + ++++ + EL Q +S+
Sbjct: 3991 IGQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLEHEL-------QKHVSRQD 4043
Query: 538 KLQQHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNL 597
LQQ Q+ A DL+ +P P S + I+Q +K FR ++ +
Sbjct: 4044 TLQQCQAW--LSAVQPDLE----------PSPQPPLSRAEAIKQ--VKHFRALQEQARTY 4089
Query: 598 IAL 600
+ L
Sbjct: 4090 LDL 4092
Score = 32.3 bits (72), Expect = 2.0
Identities = 55/278 (19%), Positives = 109/278 (39%), Gaps = 50/278 (17%)
Query: 90 FDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEESVPSGENQSV 149
F +FE + W+ E NA + ++ + + K+ + S+L S+
Sbjct: 1451 FGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKL----------SSI 1500
Query: 150 TGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMA 209
G +EE Q + E I+ ++ + E+L Q L+G + +
Sbjct: 1501 VGLEEEAQSFAQFVTTGESARIKA-------KLTQIRRYGEELREHAQCLEGTILGHLSQ 1553
Query: 210 SEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKL 269
+K +E L+++ QSV E D+++ + S T K+
Sbjct: 1554 QQK--------FEENLRKIQ-------------QSVSEFEDKLAVPIKICS-SATETYKV 1591
Query: 270 LSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMNVALRPGHDLLLAV 329
L E HMDL + +++L A S N D+ +Q + D+L
Sbjct: 1592 LQE------HMDLCQA-LESLSSAITAFSASARKVVN-RDSCVQEAAALQQQYEDILRRA 1643
Query: 330 KQQQQRFSDLRELFARRLASHLNN--VFVQQGHDQSST 365
K++Q +L + +RL L++ ++++G ++S+
Sbjct: 1644 KERQTALENLLAHW-QRLEKELSSFLTWLERGEAKASS 1680
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 38.9 bits (89), Expect = 0.022
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2389 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2441
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2500
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2561 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2620
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2621 AATKTLPN 2628
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 38.9 bits (89), Expect = 0.022
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2393 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2445
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2446 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2504
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2505 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2564
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2565 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2624
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2625 AATKTLPN 2632
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 38.9 bits (89), Expect = 0.022
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2389 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2441
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2500
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2561 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2620
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2621 AATKTLPN 2628
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 38.9 bits (89), Expect = 0.022
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2357 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2409
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2410 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2468
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2469 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2528
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2529 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2588
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2589 AATKTLPN 2596
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 38.9 bits (89), Expect = 0.022
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2526 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2578
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2579 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2637
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2638 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2697
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2698 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2757
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2758 AATKTLPN 2765
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 38.9 bits (89), Expect = 0.022
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2367 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2419
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2420 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2478
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2479 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2538
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2539 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2598
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2599 AATKTLPN 2606
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 38.9 bits (89), Expect = 0.022
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2375 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2427
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2428 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2486
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2487 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2546
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2547 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2606
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2607 AATKTLPN 2614
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 38.9 bits (89), Expect = 0.022
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2416 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2468
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2469 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2527
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2528 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2587
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2588 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2647
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2648 AATKTLPN 2655
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 38.9 bits (89), Expect = 0.022
Identities = 93/498 (18%), Positives = 198/498 (39%), Gaps = 72/498 (14%)
Query: 120 QRYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQE-LNAREEQ------DIE 172
++ +++K+D + LEE++ GE Q ++ V + QE L++ Q +
Sbjct: 2138 KKNMQEKLDALRREKVHLEETI--GEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMS 2195
Query: 173 IMMEGCEYAISNAEAFAEKLSRELQ---------------VLDGANIQSIMASEKQVNIL 217
+ + + I A+ + K S +Q + D SI E ++NI
Sbjct: 2196 SLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINIS 2255
Query: 218 MKLLDEAL---KEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
D+ + K +++L+ + + KE + Q+ E+ HL H S KL SE++
Sbjct: 2256 RLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELK 2315
Query: 275 FLVNHM-DLA---------KGHIKAL---QEGDLASSR--------GIEACTNAADALLQ 313
L + + DL+ KG+++ + QE D+ +S+ ++A L +
Sbjct: 2316 SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE 2375
Query: 314 CMNVALRPGHDLLLAVKQQ-QQRFSDLRELFARRLASHLNNVFVQQGHDQSSTLAQHSVE 372
+N+ + LL ++ Q ++LR+ + + L N+ Q+ + ++
Sbjct: 2376 EINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEI-KELENLLSQEEEENIVLEEENKKA 2434
Query: 373 LTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYEREIKDFFEVAKIK 432
+ N L+ K ++ + + K+ M L +R + D+ ++ +
Sbjct: 2435 VDKTN------QLMETLKTIKKENIQQKAQLDSFVKS-MSSLQNDRDRIVGDYQQLEERH 2487
Query: 433 MTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGN-------R 485
++ ++ + + + +K+E L L + L+ +Q + +
Sbjct: 2488 LSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIK 2547
Query: 486 RSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQQHQSM 545
SQ LL++ +L+ K+ K+ E+ L E E A +D F LQ+ +
Sbjct: 2548 DSQQKQLLEVQLQQNKELE----NKYAKL-EEKLKESEE---ANEDLRRSFNALQEEKQD 2599
Query: 546 PGTMAEAEDLDGGTLSRQ 563
E+ + L+RQ
Sbjct: 2600 LSKEIESLKVSISQLTRQ 2617
Score = 31.6 bits (70), Expect = 3.4
Identities = 69/340 (20%), Positives = 134/340 (39%), Gaps = 42/340 (12%)
Query: 137 LEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSREL 196
+E+ S E+QS T + + D EL + ++ + ++S + EL
Sbjct: 635 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDG--------DKSLSAVPDIGQCHQDEL 686
Query: 197 QVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESN 256
+ L ++ + K I K LDE KE+ + + +++ + +SE
Sbjct: 687 ERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEER 746
Query: 257 HLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMN 316
+ LS + +++E+ V +++ + + D S A N + ++
Sbjct: 747 DQL-LSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQ---TAHDNLLTEQIHSLS 802
Query: 317 VALRPGHDLLLAVKQQ-----QQRFSDLRELFARRLASHLNN--VFVQQGHDQ------- 362
+ + D+ + V Q Q +FS+ L R L S L N V +G ++
Sbjct: 803 IEAK-SKDVKIEVLQNELDDVQLQFSEQSTLI-RSLQSQLQNKESEVLEGAERVRHISSK 860
Query: 363 ----SSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLY 418
S L+Q +E+T + LL + +E L+ T K + +T+ ++
Sbjct: 861 VEELSQALSQKELEIT-----KMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMV 915
Query: 419 EREIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETE 458
+ + F +IK T KE + L R E A K++ E
Sbjct: 916 QLNEEKFSLGVEIK---TLKE--QLNLLSRAEEAKKEQVE 950
Score = 31.6 bits (70), Expect = 3.4
Identities = 69/316 (21%), Positives = 132/316 (41%), Gaps = 46/316 (14%)
Query: 62 DFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQR 121
D KR+ +L++LA + + + N E D + + ++ E+N+ +S + KLNQ+
Sbjct: 2755 DELKRKYDASLKELAQLKEQGLL--NRERDALLSETA--FSMNSTEENS-LSHLEKLNQQ 2809
Query: 122 YLRKKIDFVNVSSQL---------LEESVPSGENQSVTGGDE----EVVDEYQELNAREE 168
L K +++SSQL +++ S +N+ +E +E ++ +A +
Sbjct: 2810 LLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQP 2869
Query: 169 QDIEIMMEGCEYAISNAEAFAEKLSRELQVLD----------------GANIQSIMASEK 212
++ + A+S+ + ++L +EL+ L A +Q K
Sbjct: 2870 STSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTK 2929
Query: 213 QVNILM-KLLDEALK---EVDQIELKLSSYEEMLQSVKEQ--MDQISESNHLIHLSNTNN 266
I+ +L E L E+ Q+ ++ SS+E + +KEQ M + L HL N
Sbjct: 2930 AFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQN--- 2986
Query: 267 VKLLSEIEFLVNHMDLAKGHIKALQEGDL-ASSRGIEACTNAADALLQCMNVALRPGHDL 325
L+ E+ + K + + AS G + + L +N +L+ H
Sbjct: 2987 --LIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQK 3044
Query: 326 LLAVKQQQQRFSDLRE 341
L ++Q FS L E
Sbjct: 3045 ELRIQQLNSNFSQLLE 3060
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 38.5 bits (88), Expect = 0.028
Identities = 60/271 (22%), Positives = 111/271 (40%), Gaps = 26/271 (9%)
Query: 120 QRYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCE 179
+R R K++ + S L E E GG V E+N + E + + M E
Sbjct: 1125 ERTARAKVE--KLRSDLSRELEEISERLEEAGGATSV---QIEMNKKREAEFQKMRRDLE 1179
Query: 180 YAISNAEAFAEKLSREL--------QVLDGANIQSIMAS-EKQVNILMKLLDEALKEVDQ 230
A EA A L ++ + +D N+Q + EK+ + LD+ ++Q
Sbjct: 1180 EATLQHEATAAALRKKHADSVAELGEQID--NLQRVKQKLEKEKSEFKLELDDVTSNMEQ 1237
Query: 231 IELKLSSYEEMLQSVKEQMDQ----ISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGH 286
I ++ E+M +++++QM++ E+ ++ + KL +E L +D +
Sbjct: 1238 IIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Query: 287 IKALQEGDLASSRGIEACTNAADALLQCMNV---ALRPG-HDLLLAVKQQQQRFSDLREL 342
I L G L ++ +E + ++ N AL+ HD L +Q ++ EL
Sbjct: 1298 ISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 1357
Query: 343 FARRLASHLNNVFVQQGHDQSSTLAQHSVEL 373
+R+ S N+ Q + Q + EL
Sbjct: 1358 --QRVLSKANSEVAQWRTKYETDAIQRTEEL 1386
Score = 35.8 bits (81), Expect = 0.18
Identities = 40/187 (21%), Positives = 80/187 (42%), Gaps = 33/187 (17%)
Query: 128 DFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEA 187
D ++ +L +E S + + E+ + + Q R ++ +I ++G + + EA
Sbjct: 1761 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH---RLDEAEQIALKGGKKQLQKLEA 1817
Query: 188 FAEKLSRELQVLDGANIQSIMA---SEKQVNILMKLLDEALKE-------VDQIELKLSS 237
+L EL+ N +S+ SE+++ L +E K VD+++LK+ +
Sbjct: 1818 RVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
Query: 238 YEEMLQSVKEQMDQISESNHLIHLSNTNNV---KLLSEIEFLVNHMDLAKGHIKALQEGD 294
Y+ + +EQ +NTN K+ E++ D+A+ + L+
Sbjct: 1878 YKRQAEEAEEQ-------------ANTNLSKFRKVQHELDEAEERADIAESQVNKLR--- 1921
Query: 295 LASSRGI 301
A SR I
Sbjct: 1922 -AKSRDI 1927
Score = 32.7 bits (73), Expect = 1.5
Identities = 34/148 (22%), Positives = 58/148 (39%), Gaps = 16/148 (10%)
Query: 155 EVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQV 214
E ++E ++ A+ Q+ E +E S+ E +L E I+ +M ++
Sbjct: 1384 EELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE--------IEDLMVDVERS 1435
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
N LD+ + D+I E Q +E ++ S +T KL + E
Sbjct: 1436 NAAAAALDKKQRNFDKI------LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE 1489
Query: 275 FLVNHMDLAKGHIKALQE--GDLASSRG 300
+ H++ K K LQE DL G
Sbjct: 1490 ESLEHLETFKRENKNLQEEISDLTEQLG 1517
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 38.5 bits (88), Expect = 0.028
Identities = 85/407 (20%), Positives = 159/407 (39%), Gaps = 56/407 (13%)
Query: 152 GDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAF-AEKLSRELQ--VLDGANIQSIM 208
G E+ Q+L A E+Q + +E NAE+ A ++RELQ L N+Q +
Sbjct: 740 GKSEMKKLRQQLEAAEKQIKHLEIE------KNAESSKASSITRELQGRELKLTNLQENL 793
Query: 209 AS--------EKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIH 260
+ EK++ IL + EA +E ++ + L +EQ + +S
Sbjct: 794 SEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLS------- 846
Query: 261 LSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMNVALR 320
S++E L +LA K +E D + I+A + + + M ++
Sbjct: 847 ----------SDLEKL--RENLADMEAK-FREKDEREEQLIKAKEKLENDIAEIMKMSGD 893
Query: 321 PGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGHDQSSTLAQHSVELTLPNHHP 380
L + + + D+ EL + ++ N F+Q+ + + A+ S + H
Sbjct: 894 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 953
Query: 381 FHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER---EIKDFFEVAKIKMTGTT 437
++L R K +D K + N L YER E K E + T
Sbjct: 954 EKKELER--------KLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTL 1005
Query: 438 KESK-KFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSV--QSSGNRRSQSSSLLD 494
+++ K + S + QE E L + K + ++ + + + Q + + +SL D
Sbjct: 1006 LDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLED 1065
Query: 495 MGNMSA---SDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFK 538
+A ++LD + E L++ + L E + +F K
Sbjct: 1066 TKQTNAKLQNELDTLKENNLKNVEE--LNKSKELLTVENQKMEEFRK 1110
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 38.5 bits (88), Expect = 0.028
Identities = 85/407 (20%), Positives = 159/407 (39%), Gaps = 56/407 (13%)
Query: 152 GDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAF-AEKLSRELQ--VLDGANIQSIM 208
G E+ Q+L A E+Q + +E NAE+ A ++RELQ L N+Q +
Sbjct: 775 GKSEMKKLRQQLEAAEKQIKHLEIE------KNAESSKASSITRELQGRELKLTNLQENL 828
Query: 209 AS--------EKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIH 260
+ EK++ IL + EA +E ++ + L +EQ + +S
Sbjct: 829 SEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLS------- 881
Query: 261 LSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMNVALR 320
S++E L +LA K +E D + I+A + + + M ++
Sbjct: 882 ----------SDLEKL--RENLADMEAK-FREKDEREEQLIKAKEKLENDIAEIMKMSGD 928
Query: 321 PGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGHDQSSTLAQHSVELTLPNHHP 380
L + + + D+ EL + ++ N F+Q+ + + A+ S + H
Sbjct: 929 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 988
Query: 381 FHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER---EIKDFFEVAKIKMTGTT 437
++L R K +D K + N L YER E K E + T
Sbjct: 989 EKKELER--------KLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTL 1040
Query: 438 KESK-KFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSV--QSSGNRRSQSSSLLD 494
+++ K + S + QE E L + K + ++ + + + Q + + +SL D
Sbjct: 1041 LDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLED 1100
Query: 495 MGNMSA---SDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFK 538
+A ++LD + E L++ + L E + +F K
Sbjct: 1101 TKQTNAKLQNELDTLKENNLKNVEE--LNKSKELLTVENQKMEEFRK 1145
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 38.5 bits (88), Expect = 0.028
Identities = 40/194 (20%), Positives = 86/194 (44%), Gaps = 27/194 (13%)
Query: 120 QRYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQ--DIEIMMEG 177
+ ++R+ + + S E+S+ E + T ++V E ++ ++ IEI M G
Sbjct: 1369 KEHIRETLAKIQESQSKQEQSLNMKEKDNET---TKIVSEMEQFKPKDSALLRIEIEMLG 1425
Query: 178 CEYAISNAEAFAEKLSRE---LQVLDGA----------NIQSIMASEKQVNILMKLLDEA 224
+ + + +++E LQ L NI+ I+A + +K+
Sbjct: 1426 LSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCC 1485
Query: 225 LKE----VDQIELKLSSYEEMLQSVKEQMDQISES-----NHLIHLSNTNNVKLLSEIEF 275
LKE ++++ + LS E + ++++Q++ I++ + N+K +SE++
Sbjct: 1486 LKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQE 1545
Query: 276 LVNHMDLAKGHIKA 289
VN + K H KA
Sbjct: 1546 KVNELKQFKEHRKA 1559
Score = 36.2 bits (82), Expect = 0.14
Identities = 140/758 (18%), Positives = 305/758 (40%), Gaps = 125/758 (16%)
Query: 153 DEEVVDEYQELNA--REEQDIEIMMEGCEYAISNAEAFAEKLSRELQV-LDGANIQSIMA 209
D E++++ +++ + +E+ +++ M+E I+ E L +++ ++ ++
Sbjct: 1035 DNEIIEQQRKIFSLIQEKNELQQMLES---VIAEKEQLKTDLKENIEMTIENQEELRLLG 1091
Query: 210 SE--KQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISE-SNHLIHLSN--T 264
E KQ I+ + + A+K+ ++ E+ + +KE+ Q+ E L+++ +
Sbjct: 1092 DELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMS 1151
Query: 265 NNVKLLSEIEFLVNHM---DLAKGHIKALQEGDLASS-----RGIEACTNAADALLQCMN 316
K ++EIE L N + +L H++ + +LA +++ T L +
Sbjct: 1152 EMQKKINEIENLKNELKNKELTLEHMET-ERLELAQKLNENYEEVKSITKERKVLKELQK 1210
Query: 317 ------------------VALRPGHDLLLA---VKQQQQRFSDLRELFARRLASHLNNVF 355
L+ +L +A +K+ Q+ +LR + + A +N
Sbjct: 1211 SFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQD 1270
Query: 356 VQQGHD--QSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDY 413
+++ H Q H + LPN + ++ E + + + TK+
Sbjct: 1271 LEKSHTKLQEEIPVLHEEQELLPN-------VKEVSETQETMNELELLTEQSTTKDSTTL 1323
Query: 414 LSRLYER-EIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTS 472
ER + + F+ ++ ++ TKE T +K+ E H + T
Sbjct: 1324 ARIEMERLRLNEKFQESQEEIKSLTKERDNLKT-------IKEALEVKHDQLKEHIRETL 1376
Query: 473 SLNKLSVQSSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDF 532
+ +Q S +++ QS ++ + N + TK EQ + L E +
Sbjct: 1377 A----KIQESQSKQEQSLNMKEKDN---------ETTKIVSEMEQFKPKDSALLRIEIEM 1423
Query: 533 ISKFFKLQQ-HQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIF-RCI 590
+ +LQ+ H M E +DL + SE D +++ + +I + +
Sbjct: 1424 LGLSKRLQESHDEMKSVAKEKDDLQ----------RLQEVLQSESDQLKENIKEIVAKHL 1473
Query: 591 EPELNNLIA---LGDKIDSFNSLYM-LVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRN 646
E E +A L ++ ++ N L + L + + T Q A ++ L N ++
Sbjct: 1474 ETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEA--INDKLQN---KIQEI 1528
Query: 647 FDKCISNQIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRG-DLDKAYTKL 705
++K I+Q+ EV + KV L +F+E +S ++ E + +L +
Sbjct: 1529 YEKEEQFNIKQISEV----QEKVNEL---KQFKEHRKAKDSALQSIESKMLELTNRLQES 1581
Query: 706 IRGVFVNVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLE--AEKKEAKQKYTDHL 763
+ + +++ E K ++ + +E +LK + E A+ KE+++K L
Sbjct: 1582 QEEIQIMIKE--KEEMKRVQEALQIER--------DQLKENTKEIVAKMKESQEKEYQFL 1631
Query: 764 QSYVIYSLGQPLEKLNHFFEGVEARV--AQGIREEEV--SYQLAFNKQELRKVIKEYPG- 818
+ + + + ++ H E E + + I E + + L N +E+R V KE
Sbjct: 1632 KMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDL 1691
Query: 819 KEVKKGL--------DNLYKKVDKHLCEEENLLQVVWH 848
+ V++ L +NL + + + L ++E L V H
Sbjct: 1692 RSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMH 1729
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,818,826
Number of Sequences: 37866
Number of extensions: 1237608
Number of successful extensions: 5317
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 217
Number of HSP's that attempted gapping in prelim test: 4847
Number of HSP's gapped (non-prelim): 710
length of query: 894
length of database: 18,247,518
effective HSP length: 111
effective length of query: 783
effective length of database: 14,044,392
effective search space: 10996758936
effective search space used: 10996758936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.