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Search of human proteins with 30410716
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30410716 exocyst complex component 1 isoform 2 [Homo
sapiens]
(879 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30410716 exocyst complex component 1 isoform 2 [Homo sapiens] 1735 0.0
gi|67944634 exocyst complex component 1 isoform 1 [Homo sapiens] 1722 0.0
gi|30410720 exocyst complex component 1 isoform 1 [Homo sapiens] 1722 0.0
gi|21426793 amisyn [Homo sapiens] 86 1e-16
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 49 2e-05
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 42 0.002
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 42 0.002
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 42 0.002
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 42 0.002
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 42 0.002
gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo s... 42 0.002
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 42 0.003
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 41 0.006
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 40 0.012
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 40 0.012
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 39 0.021
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 39 0.021
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 39 0.021
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 39 0.021
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 39 0.021
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 39 0.021
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 39 0.021
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 39 0.021
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 39 0.028
gi|71061468 centromere protein E [Homo sapiens] 39 0.028
gi|118498356 kinectin 1 isoform a [Homo sapiens] 38 0.036
gi|118498368 kinectin 1 isoform c [Homo sapiens] 38 0.036
gi|33620775 kinectin 1 isoform a [Homo sapiens] 38 0.036
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 38 0.047
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 38 0.047
>gi|30410716 exocyst complex component 1 isoform 2 [Homo sapiens]
Length = 879
Score = 1735 bits (4493), Expect = 0.0
Identities = 879/879 (100%), Positives = 879/879 (100%)
Query: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK
Sbjct: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
Query: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ
Sbjct: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
Query: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY
Sbjct: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
Query: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE
Sbjct: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
Query: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG
Sbjct: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
Query: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH
Sbjct: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
Query: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER
Sbjct: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
Query: 421 EIKDFFEVAKIKMTGTTKESKKFGLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDM 480
EIKDFFEVAKIKMTGTTKESKKFGLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDM
Sbjct: 421 EIKDFFEVAKIKMTGTTKESKKFGLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDM 480
Query: 481 GNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQQHQSMPGTMAEAEDL 540
GNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQQHQSMPGTMAEAEDL
Sbjct: 481 GNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQQHQSMPGTMAEAEDL 540
Query: 541 DGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIALGDKIDSFNSLYMLVK 600
DGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIALGDKIDSFNSLYMLVK
Sbjct: 541 DGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIALGDKIDSFNSLYMLVK 600
Query: 601 MSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGILPFV 660
MSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGILPFV
Sbjct: 601 MSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGILPFV 660
Query: 661 AEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANESQKTPRDVVMMENFHH 720
AEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANESQKTPRDVVMMENFHH
Sbjct: 661 AEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANESQKTPRDVVMMENFHH 720
Query: 721 IFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNHFFEGVEARVAQGIRE 780
IFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNHFFEGVEARVAQGIRE
Sbjct: 721 IFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNHFFEGVEARVAQGIRE 780
Query: 781 EEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEENLLQVVWHSMQDEFI 840
EEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEENLLQVVWHSMQDEFI
Sbjct: 781 EEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEENLLQVVWHSMQDEFI 840
Query: 841 RQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 879
RQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH
Sbjct: 841 RQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 879
>gi|67944634 exocyst complex component 1 isoform 1 [Homo sapiens]
Length = 894
Score = 1722 bits (4461), Expect = 0.0
Identities = 878/894 (98%), Positives = 878/894 (98%), Gaps = 15/894 (1%)
Query: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK
Sbjct: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
Query: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ
Sbjct: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
Query: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY
Sbjct: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
Query: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE
Sbjct: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
Query: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG
Sbjct: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
Query: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH
Sbjct: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
Query: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER
Sbjct: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
Query: 421 EIKDFFEVAKIKMTGTTKESKKF---------------GLHGSSGKLTGSTSSLNKLSVQ 465
EIKDFFEVAKIKMTGTTKESKKF LHGSSGKLTGSTSSLNKLSVQ
Sbjct: 421 EIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQ 480
Query: 466 SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ 525
SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ
Sbjct: 481 SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ 540
Query: 526 QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL 585
QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL
Sbjct: 541 QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL 600
Query: 586 GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE 645
GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE
Sbjct: 601 GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE 660
Query: 646 VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES 705
VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES
Sbjct: 661 VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES 720
Query: 706 QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH 765
QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH
Sbjct: 721 QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH 780
Query: 766 FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE 825
FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE
Sbjct: 781 FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE 840
Query: 826 NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 879
NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH
Sbjct: 841 NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 894
>gi|30410720 exocyst complex component 1 isoform 1 [Homo sapiens]
Length = 894
Score = 1722 bits (4461), Expect = 0.0
Identities = 878/894 (98%), Positives = 878/894 (98%), Gaps = 15/894 (1%)
Query: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK
Sbjct: 1 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK 60
Query: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ
Sbjct: 61 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ 120
Query: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY
Sbjct: 121 RYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEY 180
Query: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE
Sbjct: 181 AISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEE 240
Query: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG
Sbjct: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRG 300
Query: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH
Sbjct: 301 IEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGH 360
Query: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER
Sbjct: 361 DQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYER 420
Query: 421 EIKDFFEVAKIKMTGTTKESKKF---------------GLHGSSGKLTGSTSSLNKLSVQ 465
EIKDFFEVAKIKMTGTTKESKKF LHGSSGKLTGSTSSLNKLSVQ
Sbjct: 421 EIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQ 480
Query: 466 SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ 525
SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ
Sbjct: 481 SSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQ 540
Query: 526 QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL 585
QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL
Sbjct: 541 QHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPELNNLIAL 600
Query: 586 GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE 645
GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE
Sbjct: 601 GDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEE 660
Query: 646 VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES 705
VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES
Sbjct: 661 VKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANES 720
Query: 706 QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH 765
QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH
Sbjct: 721 QKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH 780
Query: 766 FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE 825
FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE
Sbjct: 781 FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEE 840
Query: 826 NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 879
NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH
Sbjct: 841 NLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH 894
>gi|21426793 amisyn [Homo sapiens]
Length = 210
Score = 86.3 bits (212), Expect = 1e-16
Identities = 65/200 (32%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query: 5 KHALQRDIFTPNDERLLSIVNVCKAGKKKKN-----------CFLCATVTTERPVQVKVV 53
K A+ ++IF P DER+L V V + KKK ++C +VT ++P Q +
Sbjct: 4 KSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSVTNKKPTQASIT 63
Query: 54 KVKKSDKGDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIY-KWVASSTAEKNAFI 112
KVK+ + + R+ W L L V+ D ++ EFDL FE + +WVAS+ +EK F
Sbjct: 64 KVKQFEGSTSFVRRSQWMLEQLRQVNGIDPNGDSAEFDLLFENAFDQWVASTASEKCTFF 123
Query: 113 SCIWKLNQRYLR-KKIDFVNVSSQLL-EESVPSGENQSVTGGDEEVVDEYQELNAREEQD 170
+ QRYL +K +F+N S+++ S+ SVT V Q LN R E+
Sbjct: 124 QILHHTCQRYLTDRKPEFINCQSKIMGGNSILHSAADSVTSA---VQKASQALNERGER- 179
Query: 171 IEIMMEGCEYAISNAEAFAE 190
+ E E ++A+ FAE
Sbjct: 180 LGRAEEKTEDLKNSAQQFAE 199
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 49.3 bits (116), Expect = 2e-05
Identities = 152/719 (21%), Positives = 286/719 (39%), Gaps = 106/719 (14%)
Query: 154 EEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQ 213
++ V + L R ++ I+ E C S EA E+L LQ L+ I+ + +EK
Sbjct: 285 QQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELE--KIKDLHMAEKT 342
Query: 214 VNILMKLLDEALKEVDQIE-----LKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVK 268
L+ L +A ++Q+E + + +M ++++ + ++I++ I T +
Sbjct: 343 K--LITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEE 400
Query: 269 LLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMNVALRPGHDLLLA 328
L + E K A +E + A S + A L M+ ++ +
Sbjct: 401 LREQKE---------KSERAAFEELEKALSTA-QKTEEARRKLKAEMDEQIKT-----IE 445
Query: 329 VKQQQQRFSDLRELFARRLASHLNNVFVQQGHDQSSTLAQ-HSVELTLPNHHPFHRDLLR 387
+++R S +EL R+ + +V + +Q + L + H EL + R
Sbjct: 446 KTSEEERISLQQEL--SRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTR 503
Query: 388 YAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYEREIKDFFEVAKIKMTGTTKESKKFGLHG 447
+ E +K L K+ +YL E+E ++ + ++++ KK L
Sbjct: 504 EREFQEQMKVA-------LEKSQSEYLKISQEKEQQESLALEELEL------QKKAILTE 550
Query: 448 SSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDMGNMSASDLDV---ADRTKFDK----IF 500
S KL + S SL + N S DL V A++ K +K +
Sbjct: 551 SENKLRDLQQEAETYRTRILELESSLEKSLQENKNQS-KDLAVHLEAEKNKHNKEITVMV 609
Query: 501 EQVLSELEPLC------------LAEQDFISKFFKLQQHQSMPGT----------MAEAE 538
E+ +ELE L + +Q + ++ KL++ A E
Sbjct: 610 EKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIE 669
Query: 539 DLDGGTLSRQHNCGTPLP-VSSEKDMIRQMMIKIFRCIEPELNNLIALGDKIDSFNSLYM 597
+++ TL + T L +SSE + +K +E EL+ L DK+ M
Sbjct: 670 EMNEKTLEKLDVKQTELESLSSELSEV----LKARHKLEEELSVLKDQTDKMKQELEAKM 725
Query: 598 LVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGIL 657
+ +HH Q VD + + V+++R +K + +QI Q+E + + ++ K
Sbjct: 726 DEQKNHH---QQQVD------SIIKEHEVSIQRT-EKALKDQINQLE-LLLKERDK---- 770
Query: 658 PFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNVEKVANESQKTPRDVVMMEN 717
+ E + E+ K +E G+L +A KL VF + + +E K + +
Sbjct: 771 -HLKEHQAHVENLEADIKRSE--GELQQASAKL--DVFQSYQSATHEQTKAYEEQLAQLQ 825
Query: 718 FHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIY--SLGQPLEKLNHFFEG------ 769
+ R+ ++ AE + K+ L ++ I L Q LEK N E
Sbjct: 826 QKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLT 885
Query: 770 --VEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDK-HLCEEE 825
E+++ G +E+E + Q+ K+ + ++E KE++ L K D H+ EE
Sbjct: 886 QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEE 944
Score = 31.2 bits (69), Expect = 4.4
Identities = 37/159 (23%), Positives = 77/159 (48%), Gaps = 16/159 (10%)
Query: 137 LEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEK-LSRE 195
++E + + E S +EE + QEL+ +++ +++M + E I+ + EK L+R+
Sbjct: 437 MDEQIKTIEKTS----EEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 492
Query: 196 LQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISES 255
Q L + + E++ MK+ AL++ LK+S +E +S+ ++++
Sbjct: 493 EQEL----TKKLQTREREFQEQMKV---ALEKSQSEYLKISQEKEQQESL--ALEELELQ 543
Query: 256 NHLIHLSNTNNVK-LLSEIE-FLVNHMDLAKGHIKALQE 292
I + N ++ L E E + ++L K+LQE
Sbjct: 544 KKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQE 582
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 42.4 bits (98), Expect = 0.002
Identities = 67/320 (20%), Positives = 143/320 (44%), Gaps = 53/320 (16%)
Query: 81 KDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEES 140
K +KE + + E++ +W S E+ A + K ++ ++ ++ + +EE
Sbjct: 108 KAKLKELEKHKIQLEQVQEW-KSKMQEQQADLQRRLKEARKEAKEALE---AKERYMEEM 163
Query: 141 VPSGENQSVTGGDEEVVDE-----YQELNAREEQ------DIEIMMEGCEYAISNAEAFA 189
+ + + D+E+ +E QE+ A +E+ D+EI+ E S+ A +
Sbjct: 164 ADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASS 223
Query: 190 EKLSR----ELQVLDG-ANIQSIMASEKQVNI-LMKLLDEALKEVD-------QIELKLS 236
+L + ++ D ++ + +SEKQ ++ L KL+++ +E++ +++ +LS
Sbjct: 224 YQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 283
Query: 237 SYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLA 296
E + +KEQ+D + ++ + N+ L E V + G ++A+ E
Sbjct: 284 QAESTIDELKEQVDAALGAEEMVEMLTDRNLNL----EEKVRELRETVGDLEAMNE---- 335
Query: 297 SSRGIEACTNAADALLQCMNVALRPGHDLLLA-VKQQQQRFSDLRELFA---------RR 346
E NA + L+ LR D+ A V++ Q+R +E A R+
Sbjct: 336 --MNDELQENARETELE-----LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQ 388
Query: 347 LASHLNNVFVQQGHDQSSTL 366
L +HL +V + + Q +++
Sbjct: 389 LTAHLQDVNRELTNQQEASV 408
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 42.4 bits (98), Expect = 0.002
Identities = 67/320 (20%), Positives = 143/320 (44%), Gaps = 53/320 (16%)
Query: 81 KDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEES 140
K +KE + + E++ +W S E+ A + K ++ ++ ++ + +EE
Sbjct: 222 KAKLKELEKHKIQLEQVQEW-KSKMQEQQADLQRRLKEARKEAKEALE---AKERYMEEM 277
Query: 141 VPSGENQSVTGGDEEVVDE-----YQELNAREEQ------DIEIMMEGCEYAISNAEAFA 189
+ + + D+E+ +E QE+ A +E+ D+EI+ E S+ A +
Sbjct: 278 ADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASS 337
Query: 190 EKLSR----ELQVLDG-ANIQSIMASEKQVNI-LMKLLDEALKEVD-------QIELKLS 236
+L + ++ D ++ + +SEKQ ++ L KL+++ +E++ +++ +LS
Sbjct: 338 YQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 397
Query: 237 SYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLA 296
E + +KEQ+D + ++ + N+ L E V + G ++A+ E
Sbjct: 398 QAESTIDELKEQVDAALGAEEMVEMLTDRNLNL----EEKVRELRETVGDLEAMNE---- 449
Query: 297 SSRGIEACTNAADALLQCMNVALRPGHDLLLA-VKQQQQRFSDLRELFA---------RR 346
E NA + L+ LR D+ A V++ Q+R +E A R+
Sbjct: 450 --MNDELQENARETELE-----LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQ 502
Query: 347 LASHLNNVFVQQGHDQSSTL 366
L +HL +V + + Q +++
Sbjct: 503 LTAHLQDVNRELTNQQEASV 522
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 42.4 bits (98), Expect = 0.002
Identities = 67/320 (20%), Positives = 143/320 (44%), Gaps = 53/320 (16%)
Query: 81 KDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEES 140
K +KE + + E++ +W S E+ A + K ++ ++ ++ + +EE
Sbjct: 108 KAKLKELEKHKIQLEQVQEW-KSKMQEQQADLQRRLKEARKEAKEALE---AKERYMEEM 163
Query: 141 VPSGENQSVTGGDEEVVDE-----YQELNAREEQ------DIEIMMEGCEYAISNAEAFA 189
+ + + D+E+ +E QE+ A +E+ D+EI+ E S+ A +
Sbjct: 164 ADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASS 223
Query: 190 EKLSR----ELQVLDG-ANIQSIMASEKQVNI-LMKLLDEALKEVD-------QIELKLS 236
+L + ++ D ++ + +SEKQ ++ L KL+++ +E++ +++ +LS
Sbjct: 224 YQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 283
Query: 237 SYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLA 296
E + +KEQ+D + ++ + N+ L E V + G ++A+ E
Sbjct: 284 QAESTIDELKEQVDAALGAEEMVEMLTDRNLNL----EEKVRELRETVGDLEAMNE---- 335
Query: 297 SSRGIEACTNAADALLQCMNVALRPGHDLLLA-VKQQQQRFSDLRELFA---------RR 346
E NA + L+ LR D+ A V++ Q+R +E A R+
Sbjct: 336 --MNDELQENARETELE-----LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQ 388
Query: 347 LASHLNNVFVQQGHDQSSTL 366
L +HL +V + + Q +++
Sbjct: 389 LTAHLQDVNRELTNQQEASV 408
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 42.4 bits (98), Expect = 0.002
Identities = 67/320 (20%), Positives = 143/320 (44%), Gaps = 53/320 (16%)
Query: 81 KDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEES 140
K +KE + + E++ +W S E+ A + K ++ ++ ++ + +EE
Sbjct: 242 KAKLKELEKHKIQLEQVQEW-KSKMQEQQADLQRRLKEARKEAKEALE---AKERYMEEM 297
Query: 141 VPSGENQSVTGGDEEVVDE-----YQELNAREEQ------DIEIMMEGCEYAISNAEAFA 189
+ + + D+E+ +E QE+ A +E+ D+EI+ E S+ A +
Sbjct: 298 ADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASS 357
Query: 190 EKLSR----ELQVLDG-ANIQSIMASEKQVNI-LMKLLDEALKEVD-------QIELKLS 236
+L + ++ D ++ + +SEKQ ++ L KL+++ +E++ +++ +LS
Sbjct: 358 YQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 417
Query: 237 SYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLA 296
E + +KEQ+D + ++ + N+ L E V + G ++A+ E
Sbjct: 418 QAESTIDELKEQVDAALGAEEMVEMLTDRNLNL----EEKVRELRETVGDLEAMNE---- 469
Query: 297 SSRGIEACTNAADALLQCMNVALRPGHDLLLA-VKQQQQRFSDLRELFA---------RR 346
E NA + L+ LR D+ A V++ Q+R +E A R+
Sbjct: 470 --MNDELQENARETELE-----LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQ 522
Query: 347 LASHLNNVFVQQGHDQSSTL 366
L +HL +V + + Q +++
Sbjct: 523 LTAHLQDVNRELTNQQEASV 542
>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
sapiens]
Length = 1719
Score = 42.0 bits (97), Expect = 0.002
Identities = 59/287 (20%), Positives = 125/287 (43%), Gaps = 43/287 (14%)
Query: 28 KAGKKKKNCFLCATVTTERPVQVKVVKVKKSDKGDFYKRQIA-----WALRDLAVVDAKD 82
K +KK+ F ++ + +K K + D +Q+A L+D ++
Sbjct: 690 KTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 749
Query: 83 AIKENPEFDLHFEKIYKWVASSTAEKNAFISC-IWKLNQRYLRKKIDFVNVSSQLLEESV 141
+ E EF+ F++ Y+ E+N ++ + KL Y + +++ +Q LEE V
Sbjct: 750 SQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLY-----ENLSIHNQQLEEEV 804
Query: 142 P--SGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVL 199
+ + +SV + ++ + Q ++ +E+D A +A A K++ EL+ L
Sbjct: 805 KDLADKKESVAHWEAQITEIIQWVS--DEKD----------ARGYLQALASKMTEELEAL 852
Query: 200 DGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLI 259
+++ + LD + + +++ L + Q+++E+++++ SN +
Sbjct: 853 RNSSLGTRATDMPWKMRRFAKLDMSARL--ELQSALDAEIRAKQAIQEELNKVKASNIIT 910
Query: 260 HL----SNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIE 302
S N++LLSEIE L+ + +L S +GIE
Sbjct: 911 ECKLKDSEKKNLELLSEIEQLIKDTE------------ELRSEKGIE 945
Score = 32.0 bits (71), Expect = 2.6
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 5/114 (4%)
Query: 183 SNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEML 242
S+ E E+ + Q LD A + I A EKQ+ L + ++ KE+ Q +L + + L
Sbjct: 507 SHLEQQLEEANAVRQELDDA-FRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKEL 565
Query: 243 QSV----KEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQE 292
+ K M + E N + +T KL + +DL +++L++
Sbjct: 566 KDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQ 619
>gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo
sapiens]
Length = 1638
Score = 42.0 bits (97), Expect = 0.002
Identities = 59/287 (20%), Positives = 125/287 (43%), Gaps = 43/287 (14%)
Query: 28 KAGKKKKNCFLCATVTTERPVQVKVVKVKKSDKGDFYKRQIA-----WALRDLAVVDAKD 82
K +KK+ F ++ + +K K + D +Q+A L+D ++
Sbjct: 609 KTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 668
Query: 83 AIKENPEFDLHFEKIYKWVASSTAEKNAFISC-IWKLNQRYLRKKIDFVNVSSQLLEESV 141
+ E EF+ F++ Y+ E+N ++ + KL Y + +++ +Q LEE V
Sbjct: 669 SQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLY-----ENLSIHNQQLEEEV 723
Query: 142 P--SGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVL 199
+ + +SV + ++ + Q ++ +E+D A +A A K++ EL+ L
Sbjct: 724 KDLADKKESVAHWEAQITEIIQWVS--DEKD----------ARGYLQALASKMTEELEAL 771
Query: 200 DGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLI 259
+++ + LD + + +++ L + Q+++E+++++ SN +
Sbjct: 772 RNSSLGTRATDMPWKMRRFAKLDMSARL--ELQSALDAEIRAKQAIQEELNKVKASNIIT 829
Query: 260 HL----SNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIE 302
S N++LLSEIE L+ + +L S +GIE
Sbjct: 830 ECKLKDSEKKNLELLSEIEQLIKDTE------------ELRSEKGIE 864
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 41.6 bits (96), Expect = 0.003
Identities = 54/265 (20%), Positives = 113/265 (42%), Gaps = 32/265 (12%)
Query: 133 SSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKL 192
S QL +E V Q G E+ +D+Y E ++ +E+ E ++AEA L
Sbjct: 36 SKQLEDELVSL---QKKLKGTEDELDKYSEALKDAQEKLEL----AEKKATDAEADVASL 88
Query: 193 SRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMD-- 250
+R +Q+++ + + +++++ ++ L+EA K D+ E + E Q +E+M+
Sbjct: 89 NRRIQLVE----EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQ 144
Query: 251 --QISESNHLIHLSNTNN-------VKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGI 301
Q+ E+ H+ ++ V + S++E +L++G L+E + +
Sbjct: 145 EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNL 204
Query: 302 EACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNVFVQQGHD 361
++ A+ Q ++ + V + + ++ R FA R + L ++ D
Sbjct: 205 KSLEAQAEKYSQ-----KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL-----EKSID 254
Query: 362 QSSTLAQHSVELTLPNHHPFHRDLL 386
H+ E L H + LL
Sbjct: 255 DLEEKVAHAKEENLSMHQMLDQTLL 279
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 40.8 bits (94), Expect = 0.006
Identities = 39/171 (22%), Positives = 81/171 (47%), Gaps = 22/171 (12%)
Query: 133 SSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKL 192
S QL +E V Q G E+ +D+Y E ++ +E+ E ++AEA L
Sbjct: 36 SKQLEDELVSL---QKKLKGTEDELDKYSEALKDAQEKLEL----AEKKATDAEADVASL 88
Query: 193 SRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMD-- 250
+R +Q+++ + + +++++ ++ L+EA K D+ E + E Q +E+M+
Sbjct: 89 NRRIQLVE----EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQ 144
Query: 251 --QISESNHLIHLSNTNN-------VKLLSEIEFLVNHMDLAKGHIKALQE 292
Q+ E+ H+ ++ V + S++E +L++G L+E
Sbjct: 145 EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEE 195
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 39.7 bits (91), Expect = 0.012
Identities = 64/337 (18%), Positives = 136/337 (40%), Gaps = 60/337 (17%)
Query: 155 EVVDEYQELNAREEQD---IEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASE 211
E + + + A +EQ ++++ C+ + ++ + A+ + + Q ++ +Q+ ++
Sbjct: 4000 EAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQ 4059
Query: 212 --KQVNILMKLLDEALKEVDQ---------IELKLSSYEEMLQSVKEQMDQISES----N 256
+++ L L L++ DQ EL+L+ + M+ VK+ + ++ N
Sbjct: 4060 GWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVN 4119
Query: 257 HLIHLSNTNNVKLLSEIEFLVNHM-----DLAK--GHIKALQEGDLASSRGIEACTNAAD 309
+I N K S +NH+ DL + ++ +E DL +R C N +
Sbjct: 4120 TIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVE 4179
Query: 310 ALLQCMN---------------VALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLN-- 352
L+ V L L LA+++++ DL++ +++ HLN
Sbjct: 4180 VFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQ-KQKMIEHLNLD 4238
Query: 353 --------NVFVQQGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYE 404
++Q Q L + +++++ N + R+ +LMEW + E
Sbjct: 4239 DKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAE 4298
Query: 405 GLTKN---------YMDYLSRLYEREIKDFFEVAKIK 432
L ++ MD+L+ E E K + IK
Sbjct: 4299 ALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIK 4335
Score = 32.3 bits (72), Expect = 2.0
Identities = 55/278 (19%), Positives = 109/278 (39%), Gaps = 50/278 (17%)
Query: 90 FDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEESVPSGENQSV 149
F +FE + W+ E NA + ++ + + K+ + S+L S+
Sbjct: 1458 FGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKL----------SSI 1507
Query: 150 TGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMA 209
G +EE Q + E I+ ++ + E+L Q L+G + +
Sbjct: 1508 VGLEEEAQSFAQFVTTGESARIKA-------KLTQIRRYGEELREHAQCLEGTILGHLSQ 1560
Query: 210 SEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKL 269
+K +E L+++ QSV E D+++ + S T K+
Sbjct: 1561 QQK--------FEENLRKIQ-------------QSVSEFEDKLAVPIKICS-SATETYKV 1598
Query: 270 LSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMNVALRPGHDLLLAV 329
L E HMDL + +++L A S N D+ +Q + D+L
Sbjct: 1599 LQE------HMDLCQA-LESLSSAITAFSASARKVVN-RDSCVQEAAALQQQYEDILRRA 1650
Query: 330 KQQQQRFSDLRELFARRLASHLNN--VFVQQGHDQSST 365
K++Q +L + +RL L++ ++++G ++S+
Sbjct: 1651 KERQTALENLLAHW-QRLEKELSSFLTWLERGEAKASS 1687
Score = 30.0 bits (66), Expect = 9.8
Identities = 57/281 (20%), Positives = 120/281 (42%), Gaps = 43/281 (15%)
Query: 193 SRELQVLDGANIQSIMASEK------------QVNILMKLLDEALKEVDQIELKLSSYEE 240
+R ++LD +++ S M + QV +K L+E ++ +++ E LSSY +
Sbjct: 3645 ARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSD 3704
Query: 241 MLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGH-------------I 287
S + + + + + K L +E L+ D+ KGH +
Sbjct: 3705 WYGSTHKNFKNV--ATKIDKVDTVMMGKKLKTLEVLLK--DMEKGHSLLKSAREKGERAV 3760
Query: 288 KALQEGDLASSRGIEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRL 347
K L+EG+ R + + + L + + +R H L + FSD + + +
Sbjct: 3761 KYLEEGEAERLR--KEIHDHMEQLKE-LTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWI 3817
Query: 348 ASHLNNVFVQQG-----HDQSSTLAQH-SVELTLPNHHPFHRDLLRYAK-LMEWLKS-TD 399
A + + V + +++ + L+++ S++ T+ +H P + + + L+E ++ T
Sbjct: 3818 AEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTL 3877
Query: 400 YGKYEGLTKNYMDYLS--RLYEREIKDFFE-VAKIKMTGTT 437
K + L +Y D S + EI F + + ++M G T
Sbjct: 3878 KDKIDQLQSDYQDLCSIGKAMMEEIAGFEDRLNNLQMKGDT 3918
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 39.7 bits (91), Expect = 0.012
Identities = 64/337 (18%), Positives = 136/337 (40%), Gaps = 60/337 (17%)
Query: 155 EVVDEYQELNAREEQD---IEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASE 211
E + + + A +EQ ++++ C+ + ++ + A+ + + Q ++ +Q+ ++
Sbjct: 4071 EAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQ 4130
Query: 212 --KQVNILMKLLDEALKEVDQ---------IELKLSSYEEMLQSVKEQMDQISES----N 256
+++ L L L++ DQ EL+L+ + M+ VK+ + ++ N
Sbjct: 4131 GWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVN 4190
Query: 257 HLIHLSNTNNVKLLSEIEFLVNHM-----DLAK--GHIKALQEGDLASSRGIEACTNAAD 309
+I N K S +NH+ DL + ++ +E DL +R C N +
Sbjct: 4191 TIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVE 4250
Query: 310 ALLQCMN---------------VALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLN-- 352
L+ V L L LA+++++ DL++ +++ HLN
Sbjct: 4251 VFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQ-KQKMIEHLNLD 4309
Query: 353 --------NVFVQQGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYE 404
++Q Q L + +++++ N + R+ +LMEW + E
Sbjct: 4310 DKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAE 4369
Query: 405 GLTKN---------YMDYLSRLYEREIKDFFEVAKIK 432
L ++ MD+L+ E E K + IK
Sbjct: 4370 ALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIK 4406
Score = 33.1 bits (74), Expect = 1.2
Identities = 67/337 (19%), Positives = 144/337 (42%), Gaps = 44/337 (13%)
Query: 116 WKLNQRYLRK-KIDFVNVSSQL-LEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEI 173
W+ Q L + + F NV ++L L E ++ + +E+V + + R ++I++
Sbjct: 3579 WQAYQHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQL 3638
Query: 174 --MMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEK------------QVNILMK 219
M + E + + E +R ++LD +++ S M + QV +K
Sbjct: 3639 HQMKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIK 3698
Query: 220 LLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNH 279
L+E ++ +++ E LSSY + S + + + + + K L +E L+
Sbjct: 3699 FLEEEIQSLEESESSLSSYSDWYGSTHKNFKNV--ATKIDKVDTVMMGKKLKTLEVLLK- 3755
Query: 280 MDLAKGH-------------IKALQEGDLASSRGIEACTNAADALLQCMNVALRPGHDLL 326
D+ KGH +K L+EG+ R + + + L + + +R H L
Sbjct: 3756 -DMEKGHSLLKSAREKGERAVKYLEEGEAERLR--KEIHDHMEQLKE-LTSTVRKEHMTL 3811
Query: 327 LAVKQQQQRFSDLRELFARRLASHLNNVFVQQG-----HDQSSTLAQH-SVELTLPNHHP 380
+ FSD + + +A + + V + +++ + L+++ S++ T+ +H P
Sbjct: 3812 EKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEP 3871
Query: 381 FHRDLLRYAK-LMEWLKS-TDYGKYEGLTKNYMDYLS 415
+ + + L+E ++ T K + L +Y D S
Sbjct: 3872 SVKSVREKGEALLELVQDVTLKDKIDQLQSDYQDLCS 3908
Score = 32.3 bits (72), Expect = 2.0
Identities = 55/278 (19%), Positives = 109/278 (39%), Gaps = 50/278 (17%)
Query: 90 FDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEESVPSGENQSV 149
F +FE + W+ E NA + ++ + + K+ + S+L S+
Sbjct: 1451 FGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKL----------SSI 1500
Query: 150 TGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMA 209
G +EE Q + E I+ ++ + E+L Q L+G + +
Sbjct: 1501 VGLEEEAQSFAQFVTTGESARIKA-------KLTQIRRYGEELREHAQCLEGTILGHLSQ 1553
Query: 210 SEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKL 269
+K +E L+++ QSV E D+++ + S T K+
Sbjct: 1554 QQK--------FEENLRKIQ-------------QSVSEFEDKLAVPIKICS-SATETYKV 1591
Query: 270 LSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMNVALRPGHDLLLAV 329
L E HMDL + +++L A S N D+ +Q + D+L
Sbjct: 1592 LQE------HMDLCQA-LESLSSAITAFSASARKVVN-RDSCVQEAAALQQQYEDILRRA 1643
Query: 330 KQQQQRFSDLRELFARRLASHLNN--VFVQQGHDQSST 365
K++Q +L + +RL L++ ++++G ++S+
Sbjct: 1644 KERQTALENLLAHW-QRLEKELSSFLTWLERGEAKASS 1680
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2389 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2441
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2500
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2561 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2620
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2621 AATKTLPN 2628
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2393 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2445
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2446 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2504
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2505 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2564
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2565 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2624
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2625 AATKTLPN 2632
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2389 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2441
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2500
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2561 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2620
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2621 AATKTLPN 2628
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2357 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2409
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2410 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2468
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2469 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2528
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2529 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2588
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2589 AATKTLPN 2596
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2526 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2578
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2579 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2637
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2638 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2697
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2698 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2757
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2758 AATKTLPN 2765
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2367 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2419
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2420 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2478
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2479 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2538
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2539 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2598
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2599 AATKTLPN 2606
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2375 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2427
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2428 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2486
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2487 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2546
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2547 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2606
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2607 AATKTLPN 2614
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 35/248 (14%)
Query: 157 VDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSR-ELQVLDGAN-IQSIMASEKQV 214
V E AR E+D + + AE EKL R EL + +Q++ +Q
Sbjct: 2416 VAEMSRAQARAEEDAQRFRK-------QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2468
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+ + L EA+ E+++ + KL ++LQ E+M Q + L+ + LSE +
Sbjct: 2469 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-QTVQQEQLLQETQALQQSFLSEKD 2527
Query: 275 FLVNH---MDLAKGHIKALQEGDLASSRGI--------EACTNAADALLQCMNVALRPGH 323
L+ ++ K ++ L + ++A ++ + + L+ M A R H
Sbjct: 2528 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2587
Query: 324 DLLLAVKQQQQRFSDL-------RELFA---RRLASHLNNVFVQQ----GHDQSSTLAQH 369
+ V+++Q+ L EL A +RL L + Q H + T +Q
Sbjct: 2588 EAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2647
Query: 370 SVELTLPN 377
+ TLPN
Sbjct: 2648 AATKTLPN 2655
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 38.5 bits (88), Expect = 0.028
Identities = 60/271 (22%), Positives = 111/271 (40%), Gaps = 26/271 (9%)
Query: 120 QRYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCE 179
+R R K++ + S L E E GG V E+N + E + + M E
Sbjct: 1125 ERTARAKVE--KLRSDLSRELEEISERLEEAGGATSV---QIEMNKKREAEFQKMRRDLE 1179
Query: 180 YAISNAEAFAEKLSREL--------QVLDGANIQSIMAS-EKQVNILMKLLDEALKEVDQ 230
A EA A L ++ + +D N+Q + EK+ + LD+ ++Q
Sbjct: 1180 EATLQHEATAAALRKKHADSVAELGEQID--NLQRVKQKLEKEKSEFKLELDDVTSNMEQ 1237
Query: 231 IELKLSSYEEMLQSVKEQMDQ----ISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGH 286
I ++ E+M +++++QM++ E+ ++ + KL +E L +D +
Sbjct: 1238 IIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Query: 287 IKALQEGDLASSRGIEACTNAADALLQCMNV---ALRPG-HDLLLAVKQQQQRFSDLREL 342
I L G L ++ +E + ++ N AL+ HD L +Q ++ EL
Sbjct: 1298 ISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 1357
Query: 343 FARRLASHLNNVFVQQGHDQSSTLAQHSVEL 373
+R+ S N+ Q + Q + EL
Sbjct: 1358 --QRVLSKANSEVAQWRTKYETDAIQRTEEL 1386
Score = 35.8 bits (81), Expect = 0.18
Identities = 40/187 (21%), Positives = 80/187 (42%), Gaps = 33/187 (17%)
Query: 128 DFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEA 187
D ++ +L +E S + + E+ + + Q R ++ +I ++G + + EA
Sbjct: 1761 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH---RLDEAEQIALKGGKKQLQKLEA 1817
Query: 188 FAEKLSRELQVLDGANIQSIMA---SEKQVNILMKLLDEALKE-------VDQIELKLSS 237
+L EL+ N +S+ SE+++ L +E K VD+++LK+ +
Sbjct: 1818 RVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
Query: 238 YEEMLQSVKEQMDQISESNHLIHLSNTNNV---KLLSEIEFLVNHMDLAKGHIKALQEGD 294
Y+ + +EQ +NTN K+ E++ D+A+ + L+
Sbjct: 1878 YKRQAEEAEEQ-------------ANTNLSKFRKVQHELDEAEERADIAESQVNKLR--- 1921
Query: 295 LASSRGI 301
A SR I
Sbjct: 1922 -AKSRDI 1927
Score = 32.7 bits (73), Expect = 1.5
Identities = 34/148 (22%), Positives = 58/148 (39%), Gaps = 16/148 (10%)
Query: 155 EVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQV 214
E ++E ++ A+ Q+ E +E S+ E +L E I+ +M ++
Sbjct: 1384 EELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE--------IEDLMVDVERS 1435
Query: 215 NILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
N LD+ + D+I E Q +E ++ S +T KL + E
Sbjct: 1436 NAAAAALDKKQRNFDKI------LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE 1489
Query: 275 FLVNHMDLAKGHIKALQE--GDLASSRG 300
+ H++ K K LQE DL G
Sbjct: 1490 ESLEHLETFKRENKNLQEEISDLTEQLG 1517
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 38.5 bits (88), Expect = 0.028
Identities = 40/194 (20%), Positives = 86/194 (44%), Gaps = 27/194 (13%)
Query: 120 QRYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQ--DIEIMMEG 177
+ ++R+ + + S E+S+ E + T ++V E ++ ++ IEI M G
Sbjct: 1369 KEHIRETLAKIQESQSKQEQSLNMKEKDNET---TKIVSEMEQFKPKDSALLRIEIEMLG 1425
Query: 178 CEYAISNAEAFAEKLSRE---LQVLDGA----------NIQSIMASEKQVNILMKLLDEA 224
+ + + +++E LQ L NI+ I+A + +K+
Sbjct: 1426 LSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCC 1485
Query: 225 LKE----VDQIELKLSSYEEMLQSVKEQMDQISES-----NHLIHLSNTNNVKLLSEIEF 275
LKE ++++ + LS E + ++++Q++ I++ + N+K +SE++
Sbjct: 1486 LKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQE 1545
Query: 276 LVNHMDLAKGHIKA 289
VN + K H KA
Sbjct: 1546 KVNELKQFKEHRKA 1559
Score = 31.2 bits (69), Expect = 4.4
Identities = 138/748 (18%), Positives = 301/748 (40%), Gaps = 120/748 (16%)
Query: 153 DEEVVDEYQELNA--REEQDIEIMMEGCEYAISNAEAFAEKLSRELQV-LDGANIQSIMA 209
D E++++ +++ + +E+ +++ M+E I+ E L +++ ++ ++
Sbjct: 1035 DNEIIEQQRKIFSLIQEKNELQQMLES---VIAEKEQLKTDLKENIEMTIENQEELRLLG 1091
Query: 210 SE--KQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISE-SNHLIHLSN--T 264
E KQ I+ + + A+K+ ++ E+ + +KE+ Q+ E L+++ +
Sbjct: 1092 DELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMS 1151
Query: 265 NNVKLLSEIEFLVNHM---DLAKGHIKALQEGDLASS-----RGIEACTNAADALLQCMN 316
K ++EIE L N + +L H++ + +LA +++ T L +
Sbjct: 1152 EMQKKINEIENLKNELKNKELTLEHMET-ERLELAQKLNENYEEVKSITKERKVLKELQK 1210
Query: 317 ------------------VALRPGHDLLLA---VKQQQQRFSDLRELFARRLASHLNNVF 355
L+ +L +A +K+ Q+ +LR + + A +N
Sbjct: 1211 SFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQD 1270
Query: 356 VQQGHD--QSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDY 413
+++ H Q H + LPN + ++ E + + + TK+
Sbjct: 1271 LEKSHTKLQEEIPVLHEEQELLPN-------VKEVSETQETMNELELLTEQSTTKDSTTL 1323
Query: 414 LSRLYER-EIKDFFEVAKIKMTGTTKE-----SKKFGLHGSSGKLTGSTSSLNKLSVQSS 467
ER + + F+ ++ ++ TKE + K L +L +Q S
Sbjct: 1324 ARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRE-TLAKIQES 1382
Query: 468 GNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQQ- 526
+++ QS ++ + N + TK EQ + L E + + +LQ+
Sbjct: 1383 QSKQEQSLNMKEKDN---------ETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQES 1433
Query: 527 HQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIF-RCIEPELNNLIA- 584
H M E +DL + SE D +++ + +I + +E E +A
Sbjct: 1434 HDEMKSVAKEKDDLQ----------RLQEVLQSESDQLKENIKEIVAKHLETEEELKVAH 1483
Query: 585 --LGDKIDSFNSLYM-LVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIR 641
L ++ ++ N L + L + + T Q A ++ L N ++ ++K I+
Sbjct: 1484 CCLKEQEETINELRVNLSEKETEISTIQKQLEA--INDKLQN---KIQEIYEKEEQFNIK 1538
Query: 642 QMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRG-DLDKAYTKLIRGVFVNVEK 700
Q+ EV + KV L +F+E +S ++ E + +L + + + +++
Sbjct: 1539 QISEV----QEKVNEL---KQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKE 1591
Query: 701 VANESQKTPRDVVMMENFHHIFATLSRLKISCLE--AEKKEAKQKYTDHLQSYVIYSLGQ 758
E K ++ + +E +LK + E A+ KE+++K L+ + +
Sbjct: 1592 --KEEMKRVQEALQIER--------DQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQE 1641
Query: 759 PLEKLNHFFEGVEARV--AQGIREEEV--SYQLAFNKQELRKVIKEYPG-KEVKKGL--- 810
+ ++ H E E + + I E + + L N +E+R V KE + V++ L
Sbjct: 1642 KMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVE 1701
Query: 811 -----DNLYKKVDKHLCEEENLLQVVWH 833
+NL + + + L ++E L V H
Sbjct: 1702 RDQLKENLRETITRDLEKQEELKIVHMH 1729
Score = 30.0 bits (66), Expect = 9.8
Identities = 30/139 (21%), Positives = 64/139 (46%), Gaps = 15/139 (10%)
Query: 131 NVSSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAE 190
N +++LL + E S+ + +V +Y++L E++++E+ ++ + + EA
Sbjct: 485 NPATKLLNQENIESELNSLRADYDNLVLDYEQLRT-EKEEMELKLKE-KNDLDEFEALER 542
Query: 191 KLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMD 250
K ++ + M +++ L L+ A +E +LSS E+L +E+ D
Sbjct: 543 KTKKDQE----------MQLIHEISNLKNLVKHAEVYNQDLENELSSKVELL---REKED 589
Query: 251 QISESNHLIHLSNTNNVKL 269
QI + I N+K+
Sbjct: 590 QIKKLQEYIDSQKLENIKM 608
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 38.1 bits (87), Expect = 0.036
Identities = 52/263 (19%), Positives = 116/263 (44%), Gaps = 29/263 (11%)
Query: 41 TVTTERPVQVKVVKVKKSDKGDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKW 100
T+ +E+P + V +++K + K + L + ++ +E + K
Sbjct: 719 TLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKE 778
Query: 101 VASSTAEKN---AFISCIWKLNQRYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVV 157
V A++N +F S + +L ++ + +K + +LLE E V ++ V
Sbjct: 779 VQDLKAKQNDQVSFASLVEEL-KKVIHEKDGKIKSVEELLE-----AELLKVANKEKTVQ 832
Query: 158 DEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNIL 217
D QE+ A +E+ + +E A++LS +V + N+ + E+Q+N +
Sbjct: 833 DLKQEIKALKEEIGNVQLEK-----------AQQLSITSKVQELQNL--LKGKEEQMNTM 879
Query: 218 MKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLV 277
+L+E K++ L +E +S+K + ++++ N L ++ E+E ++
Sbjct: 880 KAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHN----LKEASSASQFEELEIVL 935
Query: 278 NHMDLAKGHIKAL---QEGDLAS 297
+ ++A+ +E DL+S
Sbjct: 936 KEKENELKRLEAMLKERESDLSS 958
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 38.1 bits (87), Expect = 0.036
Identities = 52/263 (19%), Positives = 116/263 (44%), Gaps = 29/263 (11%)
Query: 41 TVTTERPVQVKVVKVKKSDKGDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKW 100
T+ +E+P + V +++K + K + L + ++ +E + K
Sbjct: 719 TLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKE 778
Query: 101 VASSTAEKN---AFISCIWKLNQRYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVV 157
V A++N +F S + +L ++ + +K + +LLE E V ++ V
Sbjct: 779 VQDLKAKQNDQVSFASLVEEL-KKVIHEKDGKIKSVEELLE-----AELLKVANKEKTVQ 832
Query: 158 DEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNIL 217
D QE+ A +E+ + +E A++LS +V + N+ + E+Q+N +
Sbjct: 833 DLKQEIKALKEEIGNVQLEK-----------AQQLSITSKVQELQNL--LKGKEEQMNTM 879
Query: 218 MKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLV 277
+L+E K++ L +E +S+K + ++++ N L ++ E+E ++
Sbjct: 880 KAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHN----LKEASSASQFEELEIVL 935
Query: 278 NHMDLAKGHIKAL---QEGDLAS 297
+ ++A+ +E DL+S
Sbjct: 936 KEKENELKRLEAMLKERESDLSS 958
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 38.1 bits (87), Expect = 0.036
Identities = 52/263 (19%), Positives = 116/263 (44%), Gaps = 29/263 (11%)
Query: 41 TVTTERPVQVKVVKVKKSDKGDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKW 100
T+ +E+P + V +++K + K + L + ++ +E + K
Sbjct: 719 TLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKE 778
Query: 101 VASSTAEKN---AFISCIWKLNQRYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVV 157
V A++N +F S + +L ++ + +K + +LLE E V ++ V
Sbjct: 779 VQDLKAKQNDQVSFASLVEEL-KKVIHEKDGKIKSVEELLE-----AELLKVANKEKTVQ 832
Query: 158 DEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNIL 217
D QE+ A +E+ + +E A++LS +V + N+ + E+Q+N +
Sbjct: 833 DLKQEIKALKEEIGNVQLEK-----------AQQLSITSKVQELQNL--LKGKEEQMNTM 879
Query: 218 MKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLV 277
+L+E K++ L +E +S+K + ++++ N L ++ E+E ++
Sbjct: 880 KAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHN----LKEASSASQFEELEIVL 935
Query: 278 NHMDLAKGHIKAL---QEGDLAS 297
+ ++A+ +E DL+S
Sbjct: 936 KEKENELKRLEAMLKERESDLSS 958
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 37.7 bits (86), Expect = 0.047
Identities = 34/148 (22%), Positives = 65/148 (43%), Gaps = 7/148 (4%)
Query: 171 IEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASE---KQVNILMKLLDEALKE 227
++ ++E + IS+ E L E+Q+L S E KQ+ + +
Sbjct: 380 LQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNK 439
Query: 228 VDQIELKLSSYEEMLQSVKEQ----MDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLA 283
V+Q++ +LSS E + +K++ +I + + +T + L +++E L N +
Sbjct: 440 VEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDS 499
Query: 284 KGHIKALQEGDLASSRGIEACTNAADAL 311
K HI+ L+E A + DAL
Sbjct: 500 KQHIEVLKESLTAKEQRAAILQTEVDAL 527
Score = 36.2 bits (82), Expect = 0.14
Identities = 50/237 (21%), Positives = 107/237 (45%), Gaps = 32/237 (13%)
Query: 40 ATVTTERPVQVKVVKVKKSDKGDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYK 99
A T ER ++K ++V +S F K ++ +L+ +A+ +E++ K
Sbjct: 413 ALSTEEREEEMKQMEVYRSHS-KFMKNKVEQLKEELSSKEAQ------------WEELKK 459
Query: 100 WVASSTAEKNAFISCIWKLNQRYLRKKIDFVNVSSQLLEESVPSGENQSVTGGDEEVVDE 159
A AE I ++ Q RK + + + ++L E++ + + S EV+ E
Sbjct: 460 KAAGLQAE-------IGQVKQELSRKDTELLALQTKL--ETLTNQFSDSKQ--HIEVLKE 508
Query: 160 YQELNAREEQD--IEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNIL 217
L A+E++ ++ ++ + E K ++++Q D A + A E ++ L
Sbjct: 509 --SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ--DMAEEKGTQAGE--IHDL 562
Query: 218 MKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIE 274
+LD ++V+ ++ K+ + +E L+ ++QM + E + TN L+ +E
Sbjct: 563 KDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLE 619
Score = 31.6 bits (70), Expect = 3.4
Identities = 29/143 (20%), Positives = 62/143 (43%), Gaps = 16/143 (11%)
Query: 133 SSQLLEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKL 192
S+Q+LEE+ +N + +++ D ++ + R E+ E + E + A++
Sbjct: 807 SAQMLEEARRREDN--LNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE 864
Query: 193 SRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQI 252
S +EKQV L+ +++ +E++ ++ KLSS ++ L + + +
Sbjct: 865 SARTN------------AEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNL 912
Query: 253 --SESNHLIHLSNTNNVKLLSEI 273
HL + LL+ I
Sbjct: 913 RAERRKHLEEVLEMKQEALLAAI 935
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 37.7 bits (86), Expect = 0.047
Identities = 47/190 (24%), Positives = 82/190 (43%), Gaps = 25/190 (13%)
Query: 123 LRKKIDFV--NVSSQLLEESVPSGENQSVTGGDEEVVDEYQELN-------------ARE 167
LR +D V N S L E ++ V + E+V E Q L A+
Sbjct: 479 LRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQL 538
Query: 168 EQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKE 227
E+ IE + E E I E E L++ + L + S A K + K+L E++KE
Sbjct: 539 EKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKE 598
Query: 228 ----VDQIELKLSSYEEMLQSVKEQMDQISE-SNHLIHLSNTNNVKLLSEIEFLVNHMDL 282
+ +IE + ++ L+ KE+ ++ E N L HL N + ++ + ++ +
Sbjct: 599 TSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENEL-----LQKKITNLKI 653
Query: 283 AKGHIKALQE 292
I+AL++
Sbjct: 654 TCEKIEALEQ 663
Score = 33.5 bits (75), Expect = 0.89
Identities = 44/218 (20%), Positives = 87/218 (39%), Gaps = 49/218 (22%)
Query: 161 QELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKL 220
QEL + EQ ++ C+ + E ++L +E N+ S S + +
Sbjct: 265 QELEEKTEQLLD-----CKQELEQMEIELKRLQQE-----NMNLLSDARSARMYRDELDA 314
Query: 221 LDEALKEVDQIELKLSSYEEMLQSV---KEQMDQISESNHL------------------- 258
L E VD++E ++S Y+E L + K +++++ E N +
Sbjct: 315 LREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARS 374
Query: 259 --IHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMN 316
+H N++L +++ + D+ + I+ L E ++ A Q M+
Sbjct: 375 DKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEM----------AQKQSMD 424
Query: 317 VALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNNV 354
+L G +L +Q R S+L E + L +N +
Sbjct: 425 ESLHLGWEL-----EQISRTSELSEAPQKSLGHEVNEL 457
Score = 32.7 bits (73), Expect = 1.5
Identities = 51/268 (19%), Positives = 113/268 (42%), Gaps = 26/268 (9%)
Query: 91 DLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLRK--KIDFVNVSSQLLEESVPSGENQS 148
D ++Y+ + EK + + RY + I+F + L+E +NQ
Sbjct: 301 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKE-----DNQV 355
Query: 149 VTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIM 208
+ + D+ + AR ++ E+ E + A+ ++ R++ D I+ +M
Sbjct: 356 LLETKTMLEDQLEGTRARSDKLHELEKENLQL---KAKLHDMEMERDM---DRKKIEELM 409
Query: 209 ASEKQVNILMKL-LDEALK---EVDQIELKLSSYEEMLQSVKEQMDQISESNHL-IHLSN 263
+ + K +DE+L E++QI E +S+ ++++++ S L + + N
Sbjct: 410 EENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN 469
Query: 264 TNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAA----DALLQCMNVAL 319
+ K + E+ V+ ++ I +++ + S+ +E N +L C N++
Sbjct: 470 QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLS- 528
Query: 320 RPGHDLLLAVKQQQQRFSDLRELFARRL 347
DL+ Q ++ LRE R++
Sbjct: 529 ---KDLMKEKAQLEKTIETLRENSERQI 553
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,391,552
Number of Sequences: 37866
Number of extensions: 1220442
Number of successful extensions: 5098
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 215
Number of HSP's that attempted gapping in prelim test: 4631
Number of HSP's gapped (non-prelim): 690
length of query: 879
length of database: 18,247,518
effective HSP length: 111
effective length of query: 768
effective length of database: 14,044,392
effective search space: 10786093056
effective search space used: 10786093056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.