Guide to the Human Genome
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Search of human proteins with 29789403

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29789403 PDZ domain containing 8 [Homo sapiens]
         (1154 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29789403 PDZ domain containing 8 [Homo sapiens]                   2300   0.0  
gi|156119615 myosin IXA [Homo sapiens]                                 59   2e-08
gi|26051258 RAS guanyl releasing protein 4 isoform a [Homo sapiens]    46   2e-04
gi|226246586 RAS guanyl releasing protein 4 isoform g [Homo sapi...    46   2e-04
gi|226246584 RAS guanyl releasing protein 4 isoform f [Homo sapi...    46   2e-04
gi|226246581 RAS guanyl releasing protein 4 isoform e [Homo sapi...    46   2e-04
gi|226246579 RAS guanyl releasing protein 4 isoform d [Homo sapi...    46   2e-04
gi|226246577 RAS guanyl releasing protein 4 isoform c [Homo sapi...    46   2e-04
gi|226246575 RAS guanyl releasing protein 4 isoform b [Homo sapi...    46   2e-04
gi|190684646 RAS guanyl releasing protein 1 isoform b [Homo sapi...    46   2e-04
gi|190684644 RAS guanyl releasing protein 1 isoform a [Homo sapi...    46   2e-04
gi|4885563 protein kinase C, epsilon [Homo sapiens]                    45   4e-04
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       45   4e-04
gi|28557781 protein kinase C, eta [Homo sapiens]                       45   5e-04
gi|115529463 protein kinase D1 [Homo sapiens]                          44   9e-04
gi|21361142 PDZ domain containing 1 [Homo sapiens]                     44   0.001
gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]            43   0.002
gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]            43   0.002
gi|5453976 protein kinase C, theta [Homo sapiens]                      43   0.002
gi|4506067 protein kinase C, alpha [Homo sapiens]                      42   0.003
gi|5031689 protein kinase D3 [Homo sapiens]                            42   0.003
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ...    42   0.003
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    42   0.003
gi|13384594 protein kinase C, gamma [Homo sapiens]                     42   0.003
gi|47157325 protein kinase C, delta [Homo sapiens]                     42   0.003
gi|31377782 protein kinase C, delta [Homo sapiens]                     42   0.003
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     42   0.003
gi|20149588 Ras association domain family 1 isoform A [Homo sapi...    42   0.004
gi|11386183 WAS protein family, member 2 [Homo sapiens]                42   0.004
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]             42   0.004

>gi|29789403 PDZ domain containing 8 [Homo sapiens]
          Length = 1154

 Score = 2300 bits (5959), Expect = 0.0
 Identities = 1154/1154 (100%), Positives = 1154/1154 (100%)

Query: 1    MGLLLMILASAVLGSFLTLLAQFFLLYRRQPEPPADEAARAGEGFRYIKPVPGLLLREYL 60
            MGLLLMILASAVLGSFLTLLAQFFLLYRRQPEPPADEAARAGEGFRYIKPVPGLLLREYL
Sbjct: 1    MGLLLMILASAVLGSFLTLLAQFFLLYRRQPEPPADEAARAGEGFRYIKPVPGLLLREYL 60

Query: 61   YGGGRDEEPSGAAPEGGATPTAAPETPAPPTRETCYFLNATILFLFRELRDTALTRRWVT 120
            YGGGRDEEPSGAAPEGGATPTAAPETPAPPTRETCYFLNATILFLFRELRDTALTRRWVT
Sbjct: 61   YGGGRDEEPSGAAPEGGATPTAAPETPAPPTRETCYFLNATILFLFRELRDTALTRRWVT 120

Query: 121  KKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLVRPVVPSATGEPDGPEGE 180
            KKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLVRPVVPSATGEPDGPEGE
Sbjct: 121  KKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLVRPVVPSATGEPDGPEGE 180

Query: 181  ALPAACPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRLVFTRVPFTH 240
            ALPAACPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRLVFTRVPFTH
Sbjct: 181  ALPAACPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRLVFTRVPFTH 240

Query: 241  WFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPNYKIRFKPFFPYQT 300
            WFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPNYKIRFKPFFPYQT
Sbjct: 241  WFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPNYKIRFKPFFPYQT 300

Query: 301  LQGFEEDEEHIHIQQWALTEGRLKVTLLECSRLLIFGSYDREANVHCTLELSSSVWEEKQ 360
            LQGFEEDEEHIHIQQWALTEGRLKVTLLECSRLLIFGSYDREANVHCTLELSSSVWEEKQ
Sbjct: 301  LQGFEEDEEHIHIQQWALTEGRLKVTLLECSRLLIFGSYDREANVHCTLELSSSVWEEKQ 360

Query: 361  RSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIG 420
            RSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIG
Sbjct: 361  RSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIG 420

Query: 421  GVKITSTLQVLKLIKQAGDRVLVYYERPVGQSNQGAVLQDNFGQLEENFLSSSCQSGYEE 480
            GVKITSTLQVLKLIKQAGDRVLVYYERPVGQSNQGAVLQDNFGQLEENFLSSSCQSGYEE
Sbjct: 421  GVKITSTLQVLKLIKQAGDRVLVYYERPVGQSNQGAVLQDNFGQLEENFLSSSCQSGYEE 480

Query: 481  EAAGLTVDTESRELDSEFEDLASDVRAQNEFKDEAQSLSHSPKRVPTTLSIKPLGAISPV 540
            EAAGLTVDTESRELDSEFEDLASDVRAQNEFKDEAQSLSHSPKRVPTTLSIKPLGAISPV
Sbjct: 481  EAAGLTVDTESRELDSEFEDLASDVRAQNEFKDEAQSLSHSPKRVPTTLSIKPLGAISPV 540

Query: 541  LNRKLAVGSHPLPPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPVPPRPQAKVP 600
            LNRKLAVGSHPLPPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPVPPRPQAKVP
Sbjct: 541  LNRKLAVGSHPLPPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPVPPRPQAKVP 600

Query: 601  LPSADAPNQAEPDVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQFLAKQEVAKD 660
            LPSADAPNQAEPDVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQFLAKQEVAKD
Sbjct: 601  LPSADAPNQAEPDVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQFLAKQEVAKD 660

Query: 661  VTSETSCPTKDSSDDRQTWESSEILYRNKLGKWTRTRASCLFDIEACHRYLNIALWCRDP 720
            VTSETSCPTKDSSDDRQTWESSEILYRNKLGKWTRTRASCLFDIEACHRYLNIALWCRDP
Sbjct: 661  VTSETSCPTKDSSDDRQTWESSEILYRNKLGKWTRTRASCLFDIEACHRYLNIALWCRDP 720

Query: 721  FKLGGLICLGHVSLKLEDVALGCLATSNTEYLSKLRLEAPSPKAIVTRTALRNLSMQKGF 780
            FKLGGLICLGHVSLKLEDVALGCLATSNTEYLSKLRLEAPSPKAIVTRTALRNLSMQKGF
Sbjct: 721  FKLGGLICLGHVSLKLEDVALGCLATSNTEYLSKLRLEAPSPKAIVTRTALRNLSMQKGF 780

Query: 781  NDKFCYGDITIHFKYLKEGESDHHVVTNVEKEKEPHLVEEVSVLPKEEQFVGQMGLTENK 840
            NDKFCYGDITIHFKYLKEGESDHHVVTNVEKEKEPHLVEEVSVLPKEEQFVGQMGLTENK
Sbjct: 781  NDKFCYGDITIHFKYLKEGESDHHVVTNVEKEKEPHLVEEVSVLPKEEQFVGQMGLTENK 840

Query: 841  HSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRIDR 900
            HSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRIDR
Sbjct: 841  HSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRIDR 900

Query: 901  TLKNLRLEGQETLLGLPPRVDAEASKSVNKTTGLTRHIINTSSRLLNLRQVSKTRLSEPG 960
            TLKNLRLEGQETLLGLPPRVDAEASKSVNKTTGLTRHIINTSSRLLNLRQVSKTRLSEPG
Sbjct: 901  TLKNLRLEGQETLLGLPPRVDAEASKSVNKTTGLTRHIINTSSRLLNLRQVSKTRLSEPG 960

Query: 961  TDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKRGNSTGIKLVRKEGGLDDSVFIAVKEIG 1020
            TDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKRGNSTGIKLVRKEGGLDDSVFIAVKEIG
Sbjct: 961  TDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKRGNSTGIKLVRKEGGLDDSVFIAVKEIG 1020

Query: 1021 RDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDTRKKSLLSAALAKS 1080
            RDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDTRKKSLLSAALAKS
Sbjct: 1021 RDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDTRKKSLLSAALAKS 1080

Query: 1081 GERLQALTLLMIHYRAGIEDIETLESLSLDQHSKKISKYTDDTEEDLDNEISQLIDSQPF 1140
            GERLQALTLLMIHYRAGIEDIETLESLSLDQHSKKISKYTDDTEEDLDNEISQLIDSQPF
Sbjct: 1081 GERLQALTLLMIHYRAGIEDIETLESLSLDQHSKKISKYTDDTEEDLDNEISQLIDSQPF 1140

Query: 1141 SSISDDLFGPSESV 1154
            SSISDDLFGPSESV
Sbjct: 1141 SSISDDLFGPSESV 1154


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 28/106 (26%)

Query: 794  KYLKEGESDHHVVTNVEK-------EKEPHLVEEVSVLPKEEQFVGQMGLTENKHSFQDT 846
            +Y+ E ++     T V K       +KE  LVEE                  N H F+ T
Sbjct: 1963 EYMNEFKTSDCTATKVPKTERKKRRKKETDLVEE-----------------HNGHIFKAT 2005

Query: 847  QFQNPTWCDYCKKKVWTK-AASQCMFCAYVCHKKCQEKCLAETSVC 891
            Q+  PT+C+YC   +W    AS C  C Y CHKKC   CL  T+ C
Sbjct: 2006 QYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKC---CLKTTAKC 2048


>gi|26051258 RAS guanyl releasing protein 4 isoform a [Homo sapiens]
          Length = 673

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 2/49 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAE 887
           H+F +  F+ PT+CD C   +W  TK   +C  C   CHK C+++   E
Sbjct: 541 HTFHEVTFRKPTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVE 589


>gi|226246586 RAS guanyl releasing protein 4 isoform g [Homo
           sapiens]
          Length = 576

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 2/49 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAE 887
           H+F +  F+ PT+CD C   +W  TK   +C  C   CHK C+++   E
Sbjct: 444 HTFHEVTFRKPTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVE 492


>gi|226246584 RAS guanyl releasing protein 4 isoform f [Homo
           sapiens]
          Length = 484

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 2/49 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAE 887
           H+F +  F+ PT+CD C   +W  TK   +C  C   CHK C+++   E
Sbjct: 352 HTFHEVTFRKPTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVE 400


>gi|226246581 RAS guanyl releasing protein 4 isoform e [Homo
           sapiens]
          Length = 639

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 2/49 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAE 887
           H+F +  F+ PT+CD C   +W  TK   +C  C   CHK C+++   E
Sbjct: 507 HTFHEVTFRKPTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVE 555


>gi|226246579 RAS guanyl releasing protein 4 isoform d [Homo
           sapiens]
          Length = 604

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 2/49 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAE 887
           H+F +  F+ PT+CD C   +W  TK   +C  C   CHK C+++   E
Sbjct: 472 HTFHEVTFRKPTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVE 520


>gi|226246577 RAS guanyl releasing protein 4 isoform c [Homo
           sapiens]
          Length = 581

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 2/49 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAE 887
           H+F +  F+ PT+CD C   +W  TK   +C  C   CHK C+++   E
Sbjct: 449 HTFHEVTFRKPTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVE 497


>gi|226246575 RAS guanyl releasing protein 4 isoform b [Homo
           sapiens]
          Length = 659

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 2/49 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAE 887
           H+F +  F+ PT+CD C   +W  TK   +C  C   CHK C+++   E
Sbjct: 527 HTFHEVTFRKPTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVE 575


>gi|190684646 RAS guanyl releasing protein 1 isoform b [Homo
           sapiens]
          Length = 762

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 13/122 (10%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQE------KCLAETSVCG 892
           H+FQ+T +  PT+CD C   +W   K   +C  C   CHK+C++      K  A+  V  
Sbjct: 507 HNFQETTYLKPTFCDNCAGFLWGVIKQGYRCKDCGMNCHKQCKDLVVFECKKRAKNPVAP 566

Query: 893 ATDRRIDRTLKNLRLEGQETLLGLPPR-----VDAEASKSVNKTTGLTRHIINTSSRLLN 947
             +      + NL   G + LL  P        + EA +   ++   T  ++  SS+ ++
Sbjct: 567 TENNTSVGPVSNLCSLGAKDLLHAPEEGPFTFPNGEAVEHGEESKDRTIMLMGVSSQKIS 626

Query: 948 LR 949
           LR
Sbjct: 627 LR 628


>gi|190684644 RAS guanyl releasing protein 1 isoform a [Homo
           sapiens]
          Length = 797

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 13/122 (10%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQE------KCLAETSVCG 892
           H+FQ+T +  PT+CD C   +W   K   +C  C   CHK+C++      K  A+  V  
Sbjct: 542 HNFQETTYLKPTFCDNCAGFLWGVIKQGYRCKDCGMNCHKQCKDLVVFECKKRAKNPVAP 601

Query: 893 ATDRRIDRTLKNLRLEGQETLLGLPPR-----VDAEASKSVNKTTGLTRHIINTSSRLLN 947
             +      + NL   G + LL  P        + EA +   ++   T  ++  SS+ ++
Sbjct: 602 TENNTSVGPVSNLCSLGAKDLLHAPEEGPFTFPNGEAVEHGEESKDRTIMLMGVSSQKIS 661

Query: 948 LR 949
           LR
Sbjct: 662 LR 663


>gi|4885563 protein kinase C, epsilon [Homo sapiens]
          Length = 737

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)

Query: 839 NKHSFQDTQFQNPTWCDYCKKKVW---TKAASQCMFCAYVCHKKCQE 882
           N H F  T  + PT+C +C+  +W    K   QC  C  V HK+C E
Sbjct: 168 NGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHE 214



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 8/102 (7%)

Query: 809 VEKEKEPHLVEEVSVLPKEE--QFVGQMGLTENK-HSFQDTQFQNPTWCDYCKKKVW--T 863
           V K     ++ + + L K+E    VG    + N  H F    ++ PT+CD+C   +W   
Sbjct: 208 VHKRCHELIITKCAGLKKQETPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLL 267

Query: 864 KAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRIDRTLKNL 905
           +   QC  C    H++C+         CG   R I + L +L
Sbjct: 268 RQGLQCKVCKMNVHRRCETNVAPN---CGVDARGIAKVLADL 306


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 42/164 (25%), Positives = 67/164 (40%), Gaps = 15/164 (9%)

Query: 472 SSCQSGYEEEAAGLTVDTESRELDSEFEDLASDVRAQNEFKDEAQSLSHSPKRVPTTLSI 531
           +S +  + E  + L  +T + E  +E + LA+     +E   EAQS    P    T+   
Sbjct: 499 TSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQS----PLSEETSAEE 554

Query: 532 KPLGAISPVLNRKLAVGSHPLPPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPV 591
            P    SP       V     P ++Q   G +       E +   Q+   T+ SA + P 
Sbjct: 555 APAEVQSPSAK---GVSIEEAPLELQPPSGEETT---AEEASAAIQLLAATEASAEEAPA 608

Query: 592 PPRPQAKVPLPSADAPNQAEPDVLVEKPEKVVPPPLVDKSAEKQ 635
             +P      P+ +AP + +P    E P +V PPP  +  AE Q
Sbjct: 609 EVQPP-----PAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ 647



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 10/127 (7%)

Query: 553 PPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSA----FKPPVPPRPQAKVPLPSADAPN 608
           PP  ++    +PPP + +    PA+V  P    A      PP    P    P P+ +AP 
Sbjct: 613 PPAEEAPAEVQPPPAEEA----PAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 668

Query: 609 QAEPDVLVEKPEKVVPPPLVDKSAEKQAKNVDA--IDDAAAPKQFLAKQEVAKDVTSETS 666
           + +P    E P +V   P  +   E+    V +   DD  A +  + K     D+     
Sbjct: 669 EVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEE 728

Query: 667 CPTKDSS 673
            P  ++S
Sbjct: 729 FPIGEAS 735


>gi|28557781 protein kinase C, eta [Homo sapiens]
          Length = 683

 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 4/71 (5%)

Query: 839 NKHSFQDTQFQNPTWCDYCKKKVW---TKAASQCMFCAYVCHKKCQEKCLAETSVCGATD 895
           N H F  T  + PT+C +C++ +W    K   QC  C  V HK+C    +     C    
Sbjct: 170 NGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHH-LIVTACTCQNNI 228

Query: 896 RRIDRTLKNLR 906
            ++D  +   R
Sbjct: 229 NKVDSKIAEQR 239



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 14/94 (14%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRI 898
           H F    ++ PT+CD+C   +W   +   QC  C    H +CQ         CG     +
Sbjct: 246 HKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPN---CGVNAVEL 302

Query: 899 DRTLKNLRLEGQETLLGLPPRVDAEASKSVNKTT 932
            +TL           +GL P   +  SK V+++T
Sbjct: 303 AKTLAG---------MGLQPGNISPTSKLVSRST 327


>gi|115529463 protein kinase D1 [Homo sapiens]
          Length = 912

 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 6/58 (10%)

Query: 841 HSFQDTQFQNPTWCDYCKK--KVWTKAASQCMFCAYVCHKKCQEK----CLAETSVCG 892
           H+F    +  PT C YCKK  K   +   QC  C + CHK+C  K    CL E ++ G
Sbjct: 271 HTFVIHSYTRPTVCQYCKKLLKGLFRQGLQCKDCRFNCHKRCAPKVPNNCLGEVTING 328



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 8/75 (10%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRI 898
           H+     ++ P +CD+C + +W   +   +C  C    HK+C  K     + C    R  
Sbjct: 147 HALFVHSYRAPAFCDHCGEMLWGLVRQGLKCEGCGLNYHKRCAFKI---PNNCSGVRR-- 201

Query: 899 DRTLKNLRLEGQETL 913
            R L N+ L G  T+
Sbjct: 202 -RRLSNVSLTGVSTI 215


>gi|21361142 PDZ domain containing 1 [Homo sapiens]
          Length = 519

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 35/111 (31%), Positives = 56/111 (50%), Gaps = 21/111 (18%)

Query: 368 ELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIGGVKITST 427
           +L K   Q+ G  LR+ + T+G+    ++  V   SPA  A LQ GDR++ I GV +   
Sbjct: 11  KLSKQEGQNYGFFLRIEKDTEGH----LVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKE 66

Query: 428 --LQVLKLIKQAGDRVLVY------YERPV---------GQSNQGAVLQDN 461
             +QV+ L++++G+ V +       YE+ V         GQS +   L DN
Sbjct: 67  EHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDN 117


>gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]
          Length = 671

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVWT--KAASQCMFCAYVCHKKCQE 882
           H F    F+ PT+C +C   +W   K   QC  C +V HK+C E
Sbjct: 37  HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHE 80



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 15/92 (16%)

Query: 839 NKHSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGA--T 894
           +KH F+   + +PT+CD+C   ++       +C  C    HK+C    +   S+CG   T
Sbjct: 100 SKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRC---VMNVPSLCGTDHT 156

Query: 895 DRR--------IDRTLKNLRLEGQETLLGLPP 918
           +RR        IDR +  + +   + L+ + P
Sbjct: 157 ERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDP 188


>gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]
          Length = 673

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVWT--KAASQCMFCAYVCHKKCQE 882
           H F    F+ PT+C +C   +W   K   QC  C +V HK+C E
Sbjct: 37  HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHE 80



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 15/92 (16%)

Query: 839 NKHSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGA--T 894
           +KH F+   + +PT+CD+C   ++       +C  C    HK+C    +   S+CG   T
Sbjct: 100 SKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRC---VMNVPSLCGTDHT 156

Query: 895 DRR--------IDRTLKNLRLEGQETLLGLPP 918
           +RR        IDR +  + +   + L+ + P
Sbjct: 157 ERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDP 188


>gi|5453976 protein kinase C, theta [Homo sapiens]
          Length = 706

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAE 887
           H F  T F  PT+C  C + VW   K   QC  C    HKKC +K +A+
Sbjct: 160 HEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAK 208



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 18/79 (22%), Positives = 36/79 (45%), Gaps = 5/79 (6%)

Query: 826 KEEQFVGQMGLTENKHSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEK 883
           +E  F  +    +  H F+   +++PT+C++C   +W   +   +C  C    H +CQ K
Sbjct: 217 RETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTK 276

Query: 884 CLAETSVCGATDRRIDRTL 902
                ++CG   + +   L
Sbjct: 277 V---ANLCGINQKLMAEAL 292


>gi|4506067 protein kinase C, alpha [Homo sapiens]
          Length = 672

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVWT--KAASQCMFCAYVCHKKCQE 882
           H F    F+ PT+C +C   +W   K   QC  C +V HK+C E
Sbjct: 37  HKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHE 80



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 10/71 (14%)

Query: 839 NKHSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGATDR 896
           +KH F+   + +PT+CD+C   ++       +C  C    HK+C    +   S+CG    
Sbjct: 100 SKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQC---VINVPSLCG---- 152

Query: 897 RIDRTLKNLRL 907
            +D T K  R+
Sbjct: 153 -MDHTEKRGRI 162


>gi|5031689 protein kinase D3 [Homo sapiens]
          Length = 890

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 6/58 (10%)

Query: 841 HSFQDTQFQNPTWCDYCKK--KVWTKAASQCMFCAYVCHKKCQEK----CLAETSVCG 892
           H+F    +  PT C YCK+  K   +   QC  C + CHK+C  K    CL E +  G
Sbjct: 272 HTFAVHSYTRPTICQYCKRLLKGLFRQGMQCKDCKFNCHKRCASKVPRDCLGEVTFNG 329



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 17/189 (8%)

Query: 788 DITIHFKYLKEGESDHHVVTNVEKEKEPHLVEEV-SVLPKEEQFVGQMGLTENKHSFQDT 846
           D  + F++    E+   ++T+ ++  E  LVE V S L   E F          H+    
Sbjct: 107 DKILLFRHDMNSENILQLITSADEIHEGDLVEVVLSALATVEDF------QIRPHTLYVH 160

Query: 847 QFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRIDRTLKN 904
            ++ PT+CDYC + +W   +   +C  C    HK+C  K     +  G   RR    L N
Sbjct: 161 SYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFK--IPNNCSGVRKRR----LSN 214

Query: 905 LRLEGQETLLGLP--PRVDAEASKSVNKTTGLTRHIINTSSRLLNLRQVSKTRLSEPGTD 962
           + L G    +  P  P   A  S+  +     ++ I + S R + + ++   R+  P T 
Sbjct: 215 VSLPGPGLSVPRPLQPEYVALPSEESHVHQEPSKRIPSWSGRPIWMEKMVMCRVKVPHTF 274

Query: 963 LVEPSPKHT 971
            V    + T
Sbjct: 275 AVHSYTRPT 283


>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
           sapiens]
          Length = 722

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 35/138 (25%), Positives = 53/138 (38%), Gaps = 15/138 (10%)

Query: 553 PPKIQSKDGNKPPPLKTSE----------ITDPAQVSKPTQGSAFKPPVPPRPQAKVPLP 602
           PP+ Q+   N PP   T            +  P     P Q     PPVPP+PQ   P  
Sbjct: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP--PPA 262

Query: 603 SADAPNQAEPDVLVEKPEKVVPPPLVDKSAEKQA-KNVDAIDD--AAAPKQFLAKQEVAK 659
            A  P Q+ P ++   P+ V     V + A+      +D I +  +  P+    K    +
Sbjct: 263 PAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRR 322

Query: 660 DVTSETSCPTKDSSDDRQ 677
           + +     P KD  D +Q
Sbjct: 323 ESSRPVKPPKKDVPDSQQ 340


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 35/138 (25%), Positives = 53/138 (38%), Gaps = 15/138 (10%)

Query: 553 PPKIQSKDGNKPPPLKTSE----------ITDPAQVSKPTQGSAFKPPVPPRPQAKVPLP 602
           PP+ Q+   N PP   T            +  P     P Q     PPVPP+PQ   P  
Sbjct: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP--PPA 262

Query: 603 SADAPNQAEPDVLVEKPEKVVPPPLVDKSAEKQA-KNVDAIDD--AAAPKQFLAKQEVAK 659
            A  P Q+ P ++   P+ V     V + A+      +D I +  +  P+    K    +
Sbjct: 263 PAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRR 322

Query: 660 DVTSETSCPTKDSSDDRQ 677
           + +     P KD  D +Q
Sbjct: 323 ESSRPVKPPKKDVPDSQQ 340



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 8/81 (9%)

Query: 550 HPLPPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPVPPRPQAKVP----LPSAD 605
           H  PP +       PP L  +    P Q S+P+  +A  PP P RP A  P     P   
Sbjct: 845 HSTPPHLNQHAVVSPPALHNAL---PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLP 901

Query: 606 APNQAE-PDVLVEKPEKVVPP 625
            P  A+ P VL+E  E   PP
Sbjct: 902 QPPMAQPPQVLLEDEEPPAPP 922



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 25/85 (29%), Positives = 31/85 (36%), Gaps = 8/85 (9%)

Query: 551 PLPPKIQSKDGNKPPPLKTSEITDPAQVSKP-----TQGSAFKPPVPPR---PQAKVPLP 602
           P PP+ Q +    PPP    +   PA  S P     TQ    +P +P     P      P
Sbjct: 767 PPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQP 826

Query: 603 SADAPNQAEPDVLVEKPEKVVPPPL 627
               P    P  L + PE   PP L
Sbjct: 827 ILHLPQPELPPHLPQPPEHSTPPHL 851


>gi|13384594 protein kinase C, gamma [Homo sapiens]
          Length = 697

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVWT--KAASQCMFCAYVCHKKCQE 882
           H F    F+ PT+C +C   +W   K   QC  C++V H++C E
Sbjct: 36  HKFTARFFKQPTFCSHCTDFIWGIGKQGLQCQVCSFVVHRRCHE 79



 Score = 38.1 bits (87), Expect = 0.049
 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 19/103 (18%)

Query: 839 NKHSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGATDR 896
           NKH F+   + +PT+CD+C   ++       +C  C    H++C     +  S+CG    
Sbjct: 99  NKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCVR---SVPSLCG---- 151

Query: 897 RIDRTLKNLRLEGQETLLGLPPRVDAEASKSVNKTTGLTRHII 939
            +D T +  RL+ +         + A  +  ++ T G  R++I
Sbjct: 152 -VDHTERRGRLQLE---------IRAPTADEIHVTVGEARNLI 184


>gi|47157325 protein kinase C, delta [Homo sapiens]
          Length = 676

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 2/58 (3%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGATDR 896
           H F  T F  PT+C  CK  VW   K   +C  C    HKKC +K +   +   A  R
Sbjct: 159 HEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSR 216



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 5/67 (7%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRI 898
           H F+   + +PT+CD+C   +W   K   +C  C    H KC+EK     ++CG   + +
Sbjct: 231 HRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKV---ANLCGINQKLL 287

Query: 899 DRTLKNL 905
              L  +
Sbjct: 288 AEALNQV 294


>gi|31377782 protein kinase C, delta [Homo sapiens]
          Length = 676

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 2/58 (3%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGATDR 896
           H F  T F  PT+C  CK  VW   K   +C  C    HKKC +K +   +   A  R
Sbjct: 159 HEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSR 216



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 5/67 (7%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRI 898
           H F+   + +PT+CD+C   +W   K   +C  C    H KC+EK     ++CG   + +
Sbjct: 231 HRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKV---ANLCGINQKLL 287

Query: 899 DRTLKNL 905
              L  +
Sbjct: 288 AEALNQV 294


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 45/177 (25%), Positives = 69/177 (38%), Gaps = 7/177 (3%)

Query: 497 EFEDLASDVRAQNEFKDEAQSLSHSPKRVPTTLSIKPLGAISPVLNRKLAVGSHPLPPKI 556
           E E+  S  +A++  K EA+S   +   V       P  A SPV     +      P K 
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK-SPEKAKSPVKEEAKSPEKAKSPVKE 714

Query: 557 QSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPVPPRPQAKVPL----PSADAPNQAEP 612
           ++K   K       E   P +   P +  A  P     P+    L    P A  P + E 
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774

Query: 613 DVLVEK-PEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQFLAKQEVAKDVTSETSCP 668
               +K PEK   P   +  + ++AK+    +DA AP++ + K+E  K    E   P
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKS-PLKEDAKAPEKEIPKKEEVKSPVKEEEKP 830



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 45/191 (23%), Positives = 72/191 (37%), Gaps = 14/191 (7%)

Query: 499 EDLASDVRAQNEFKDEAQSLSHS-PKRV----PTTLSIKPLGAISPVLNRKLAVGSHPLP 553
           E++ S  +A++  K++A++     PK+     P     KP         +K      P  
Sbjct: 791 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 850

Query: 554 PKIQSKDGNKP--------PPLKTSEITDPAQVSKPTQGSAFKPPVPPRPQAKVPLPSAD 605
           PK + K  +K         P  K  E  +PA V KP +            + KVP P  +
Sbjct: 851 PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA-VEKPKESKVEAKKEEAEDKKKVPTPEKE 909

Query: 606 APNQAEPDVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQFLAKQEVAKDVTSET 665
           AP + E     +  EK          A+ +  +  A    AAP++   K+E AK    + 
Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP 969

Query: 666 SCPTKDSSDDR 676
               K   DD+
Sbjct: 970 KTEAKAKEDDK 980



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 41/206 (19%), Positives = 81/206 (39%), Gaps = 10/206 (4%)

Query: 481 EAAGLTVDTESRELDSEFEDLASDVRAQNEFKDEAQSLSHSPKRVPTTLSIK---PLGAI 537
           E A   V  E++  +     + ++ ++  + K   +  + SP++  + +  +   P  A 
Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723

Query: 538 SPVLNRKLAVGSHPLPPKIQSKDGNK---PPPLKTSEITDPAQVSKPTQGSAFKPPVPPR 594
           SPV            P K ++K   K   P   KT ++  P +   P +  A  P     
Sbjct: 724 SPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP-EAKTPAKEEARSPADKFP 782

Query: 595 PQAKVPLPS-ADAPNQAEPDVL--VEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQF 651
            +AK P+     +P +A+  +    + PEK +P     KS  K+ +    +     PK+ 
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842

Query: 652 LAKQEVAKDVTSETSCPTKDSSDDRQ 677
             ++  A   T E     K+ +  ++
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKE 868



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 17/133 (12%)

Query: 553 PPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPVPPRPQAKVPLPSADAPNQAEP 612
           P K ++K   +    +  E   PA+V  P +  +     P + +AK P P A +P + E 
Sbjct: 519 PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKS-----PAKEEAKSP-PEAKSPEKEE- 571

Query: 613 DVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQFLAKQEVAKDVTS--ETSCPTK 670
               + P +V  P      A+++AK+     +A +P++  AK  V ++  S  E   P K
Sbjct: 572 ---AKSPAEVKSPEKAKSPAKEEAKSPA---EAKSPEK--AKSPVKEEAKSPAEAKSPVK 623

Query: 671 DSSDDRQTWESSE 683
           + +      +S E
Sbjct: 624 EEAKSPAEVKSPE 636


>gi|20149588 Ras association domain family 1 isoform A [Homo
           sapiens]
          Length = 340

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 4/57 (7%)

Query: 841 HSFQDTQFQNPTWCDYCKKKVW--TKAASQCMFCAYVCHKKCQEKCLAETSVCGATD 895
           H FQ       TWCD C   +W   +   QC  C + CH +C  + L     CG  D
Sbjct: 52  HRFQPAGPATHTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRC--RALVCLDCCGPRD 106


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 34/113 (30%), Positives = 44/113 (38%), Gaps = 14/113 (12%)

Query: 533 PLGAISPVLNRKLAVGSHPLPPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPVP 592
           P+G  SP      +  S P  P   +     PPP        P  +S+PT G A  PP P
Sbjct: 338 PVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPT-GGAPPPPPP 396

Query: 593 PRPQAKVPLPSADAPNQAEPDVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDA 645
           P P    P P   A  Q             +PPPL D +  K   ++ A+ DA
Sbjct: 397 PPPPGPPPPPFTGADGQ-----------PAIPPPLSDTT--KPKSSLPAVSDA 436


>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
          Length = 459

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 9/95 (9%)

Query: 792 HFKYLKE--GESDHHVVTNVEKEKEPHLVEEVSVLPKEEQFVGQMGLTENKHSFQDTQFQ 849
           H   LKE   E D      V +++   LV   ++   E     Q+   E  H+F+   F+
Sbjct: 160 HMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENE-----QIPKYEKIHNFKVHTFR 214

Query: 850 NPTWCDYCKKKVWTKAAS--QCMFCAYVCHKKCQE 882
            P WC+YC   +W   A   +C  C    HK+C +
Sbjct: 215 GPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSK 249


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,432,099
Number of Sequences: 37866
Number of extensions: 2376897
Number of successful extensions: 14264
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 435
Number of HSP's that attempted gapping in prelim test: 12307
Number of HSP's gapped (non-prelim): 1999
length of query: 1154
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1041
effective length of database: 13,968,660
effective search space: 14541375060
effective search space used: 14541375060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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