BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo sapiens] (558 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo sa... 1132 0.0 gi|24111228 solute carrier family 24 member 4 isoform 1 precurso... 1132 0.0 gi|29788985 solute carrier family 24 member 4 isoform 2 precurso... 1079 0.0 gi|31563526 solute carrier family 24 (sodium/potassium/calcium e... 704 0.0 gi|9966787 solute carrier family 24 (sodium/potassium/calcium ex... 395 e-110 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 215 7e-56 gi|45504369 solute carrier family 24, member 5 [Homo sapiens] 203 4e-52 gi|39995086 solute carrier family 24 member 6 [Homo sapiens] 77 5e-14 gi|10863913 solute carrier family 8 (sodium/calcium exchanger), ... 65 1e-10 gi|163914373 solute carrier family 8 (sodium/calcium exchanger),... 65 1e-10 gi|163914371 solute carrier family 8 (sodium/calcium exchanger),... 65 1e-10 gi|163914369 solute carrier family 8 (sodium/calcium exchanger),... 65 1e-10 gi|17865805 solute carrier family 8 (sodium/calcium exchanger), ... 63 8e-10 gi|33946304 solute carrier family 8 (sodium/calcium exchanger), ... 63 8e-10 gi|15147254 solute carrier family 8 (sodium/calcium exchanger), ... 63 8e-10 gi|33946311 solute carrier family 8 (sodium/calcium exchanger), ... 63 8e-10 gi|33946308 solute carrier family 8 (sodium/calcium exchanger), ... 60 4e-09 gi|194354001 solute carrier family 8 (sodium/calcium exchanger),... 60 4e-09 gi|57163987 solute carrier family 8 member 2 [Homo sapiens] 60 7e-09 gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 42 0.001 gi|8923842 forkhead box J2 [Homo sapiens] 40 0.006 gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 39 0.010 gi|32307177 forkhead box G1 [Homo sapiens] 39 0.010 gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 39 0.016 gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 39 0.016 gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 39 0.016 gi|169636435 caudal type homeobox 2 [Homo sapiens] 38 0.021 gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens] 38 0.028 gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens] 38 0.028 gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens] 38 0.028 >gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo sapiens] Length = 558 Score = 1132 bits (2927), Expect = 0.0 Identities = 558/558 (100%), Positives = 558/558 (100%) Query: 1 MAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVP 60 MAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVP Sbjct: 1 MAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVP 60 Query: 61 SLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCI 120 SLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCI Sbjct: 61 SLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCI 120 Query: 121 IGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILI 180 IGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILI Sbjct: 121 IGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILI 180 Query: 181 MKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNP 240 MKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNP Sbjct: 181 MKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNP 240 Query: 241 VVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSK 300 VVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSK Sbjct: 241 VVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSK 300 Query: 301 PLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK 360 PLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK Sbjct: 301 PLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK 360 Query: 361 VKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGI 420 VKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGI Sbjct: 361 VKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGI 420 Query: 421 PDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMV 480 PDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMV Sbjct: 421 PDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMV 480 Query: 481 VNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIM 540 VNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIM Sbjct: 481 VNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIM 540 Query: 541 IEFNVFTFVNLPMCREDD 558 IEFNVFTFVNLPMCREDD Sbjct: 541 IEFNVFTFVNLPMCREDD 558 >gi|24111228 solute carrier family 24 member 4 isoform 1 precursor [Homo sapiens] Length = 605 Score = 1132 bits (2927), Expect = 0.0 Identities = 558/558 (100%), Positives = 558/558 (100%) Query: 1 MAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVP 60 MAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVP Sbjct: 48 MAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVP 107 Query: 61 SLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCI 120 SLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCI Sbjct: 108 SLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCI 167 Query: 121 IGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILI 180 IGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILI Sbjct: 168 IGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILI 227 Query: 181 MKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNP 240 MKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNP Sbjct: 228 MKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNP 287 Query: 241 VVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSK 300 VVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSK Sbjct: 288 VVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSK 347 Query: 301 PLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK 360 PLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK Sbjct: 348 PLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK 407 Query: 361 VKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGI 420 VKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGI Sbjct: 408 VKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGI 467 Query: 421 PDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMV 480 PDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMV Sbjct: 468 PDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMV 527 Query: 481 VNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIM 540 VNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIM Sbjct: 528 VNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIM 587 Query: 541 IEFNVFTFVNLPMCREDD 558 IEFNVFTFVNLPMCREDD Sbjct: 588 IEFNVFTFVNLPMCREDD 605 >gi|29788985 solute carrier family 24 member 4 isoform 2 precursor [Homo sapiens] Length = 586 Score = 1079 bits (2790), Expect = 0.0 Identities = 539/558 (96%), Positives = 539/558 (96%), Gaps = 19/558 (3%) Query: 1 MAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVP 60 MAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVP Sbjct: 48 MAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVP 107 Query: 61 SLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCI 120 SLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCI Sbjct: 108 SLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCI 167 Query: 121 IGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILI 180 IGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILI Sbjct: 168 IGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILI 227 Query: 181 MKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNP 240 MKYNVKMQAFFTVKQKSIANGNPVNSELEA VKEKPQYGKNP Sbjct: 228 MKYNVKMQAFFTVKQKSIANGNPVNSELEA-------------------VKEKPQYGKNP 268 Query: 241 VVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSK 300 VVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSK Sbjct: 269 VVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSK 328 Query: 301 PLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK 360 PLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK Sbjct: 329 PLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK 388 Query: 361 VKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGI 420 VKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGI Sbjct: 389 VKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGI 448 Query: 421 PDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMV 480 PDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMV Sbjct: 449 PDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMV 508 Query: 481 VNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIM 540 VNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIM Sbjct: 509 VNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIM 568 Query: 541 IEFNVFTFVNLPMCREDD 558 IEFNVFTFVNLPMCREDD Sbjct: 569 IEFNVFTFVNLPMCREDD 586 >gi|31563526 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 [Homo sapiens] Length = 644 Score = 704 bits (1817), Expect = 0.0 Identities = 357/568 (62%), Positives = 432/568 (76%), Gaps = 25/568 (4%) Query: 6 GTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKI 65 G + +KNCT+PA+HEFP D+F+N++R+ GAV+LH+L A+YMFYALAIVCDDFFVPSLEKI Sbjct: 80 GLRNSKNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKI 139 Query: 66 CERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCG 125 CERLHLSEDVAGATFMAAGSS PELF SVIGVFIT GDVGVGTIVGSAVFNILCIIGVCG Sbjct: 140 CERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCG 199 Query: 126 LFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNV 185 LFAGQVV L+ W + RDS+YYT+SVI LIVFIYDE++ WWE LVL+++Y+ YI+IMKYN Sbjct: 200 LFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNA 259 Query: 186 KMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNPVVMVD 245 + F + K GN VN L + D S D +V LL K+ + K V+MVD Sbjct: 260 CIHQCFERRTKGA--GNMVNG-LANNAEIDDSSNCDATVVLL---KKANFHRKASVIMVD 313 Query: 246 EIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINS---ANGVSSKPL 302 E++S+ P + +F EAGLRIMIT+ F P+TRL MASR++INERQRLINS NG S + Sbjct: 314 ELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYTNGESEVAI 373 Query: 303 QNGRHENIENGNVPVENPE----------------DPQQNQEQQPPPQPPPPEPEPVEAD 346 + +ENG P P+ + +N+ + E E + Sbjct: 374 KIPIKHTVENGTGPSSAPDRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEG 433 Query: 347 FLSPFSVPEARGDKVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYI 406 +PF P + + VKW FTWPL F+L T+PNC+KPRWEK+FMVTF ++TLWIA FSY+ Sbjct: 434 PYTPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYM 493 Query: 407 MVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDI 466 MVW+VTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG+GDMAVSN+IGSNVFDI Sbjct: 494 MVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDI 553 Query: 467 LVGLGVPWGLQTMVVNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVY 526 L+GLG+PW LQT+ V+YGS +++NSRGL+YSV LLL SV +TV G+HLNKW+LD+KLG Sbjct: 554 LIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCG 613 Query: 527 VLVLYAIFLCFSIMIEFNVFTFVNLPMC 554 L+LY +FLCFSIM EFNVFTFVNLPMC Sbjct: 614 CLLLYGVFLCFSIMTEFNVFTFVNLPMC 641 >gi|9966787 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens] Length = 661 Score = 395 bits (1016), Expect = e-110 Identities = 223/571 (39%), Positives = 338/571 (59%), Gaps = 42/571 (7%) Query: 3 PVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSL 62 P++ ++N TD A ++P D+FS +ER+ GA++LH++G +YMF ALAIVCD+FFVPSL Sbjct: 102 PLSKEGESENSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSL 161 Query: 63 EKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIG 122 I E+L +S+DVAGATFMAAG S PELF S+IGVFI H +VG+GTIVGSAVFNIL +IG Sbjct: 162 TVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIG 221 Query: 123 VCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMK 182 +C LF+ +++ LTWW + RD +Y + +I+LI+F D I+WWE L+L+ Y Y++ MK Sbjct: 222 MCALFSREILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMK 281 Query: 183 YNVKMQAFFTVKQKSIANGNPV--------NSELEAGNDFYDGSYDDPSVPLLGQVKEKP 234 +NV+++ + K + N N V ++ A D D+P++P K + Sbjct: 282 FNVQVEKWV----KQMINRNKVVKVTAPEAQAKPSAARD-----KDEPTLP----AKPRL 328 Query: 235 QYGKNPVVMVDEIMSSSPPKFTF-------PEAGL--RIMITNKFGPRTRLRMASRII-- 283 Q G + + + +M +S + E G ++ + R R + I+ Sbjct: 329 QRGGSSASLHNSLMRNSIFQLMIHTLDPLAEELGSYGKLKYYDTMTEEGRFREKASILHK 388 Query: 284 -------INERQRLINSANGVSSKPLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPP 336 ++E +R +AN V L N ++E P + +P QN + Sbjct: 389 IAKKKCHVDENERQNGAANHVEKIELPNSTSTDVE--MTPSSDASEPVQNGNLSHNIEGA 446 Query: 337 PPEPEPVEADFLSPFSVPEARGDKVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITA 396 + E D + P +V ++ +P++F L +T+P+ KP KFF +TF + Sbjct: 447 EAQTADEEEDQPLSLAWPSETRKQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGS 506 Query: 397 TLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVS 456 WIAVFSY+MVW +G T+GI + IMG+T LAAGTS+PD + S+IVAR+GLGDMAVS Sbjct: 507 ITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVS 566 Query: 457 NTIGSNVFDILVGLGVPWGLQTMVVNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNK 516 +++GSN+FDI VGL +PW L T++ + V ++S GL ++VLL + +L I L K Sbjct: 567 SSVGSNIFDITVGLPLPWLLYTVIHRF-QPVAVSSNGLFCAIVLLFIMLLFVILSIALCK 625 Query: 517 WRLDRKLGVYVLVLYAIFLCFSIMIEFNVFT 547 WR+++ LG + LY +FL S+++E + T Sbjct: 626 WRMNKILGFIMFGLYFVFLVVSVLLEDRILT 656 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 215 bits (548), Expect = 7e-56 Identities = 131/348 (37%), Positives = 191/348 (54%), Gaps = 45/348 (12%) Query: 16 PAIH---EFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICERLHLS 72 P +H E+P DLFS +ER+ G V+LH+ G +Y+F ALAIVCD++FVP+L I ++L +S Sbjct: 432 PDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQIS 491 Query: 73 EDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVV 132 EDVAGATFMAAG S PELF S+IGVFI+H +VG+GTIVGSAVFNIL +IG C LF+ +++ Sbjct: 492 EDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREIL 551 Query: 133 RLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFT 192 LTWW + RD +Y + +I+LI+F D I WWE L+L++ Y FY+ MK+N ++ + Sbjct: 552 NLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWV- 610 Query: 193 VKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNPVVMVDEIMSSSP 252 K + PV + + +D S P G + VDE+ + Sbjct: 611 ---KEQLSRRPVAKVM---------ALEDLSKPGDG------------AIAVDELQDNK- 645 Query: 253 PKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSKPLQNGRHENIEN 312 K P R G + S I Q +++S + + L + E N Sbjct: 646 -KLKLPSLLTR-------GSSSTSLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLN 697 Query: 313 GNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK 360 + PQ E +P + EP + A ++P VP+ +GD+ Sbjct: 698 QGARAQ----PQAKAESKPEEE----EPAKLPAVTVTPAPVPDIKGDQ 737 Score = 184 bits (466), Expect = 2e-46 Identities = 95/244 (38%), Positives = 149/244 (61%), Gaps = 7/244 (2%) Query: 304 NGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDKVKW 363 + E E E E+ Q+ +E++ + EP+ D+ PE R + + Sbjct: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDW------PETRQKQAIY 911 Query: 364 VFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDV 423 +F P++F L +T+P+ + KFF+ TF+ + +WIA+FSY+MVW +G T+GI + Sbjct: 912 LFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEE 971 Query: 424 IMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNY 483 IMG+T LAAGTS+PD + S+IVAR+GLGDMAVS+++GSN+FDI VGL VPW L ++N Sbjct: 972 IMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW-LLFSLING 1030 Query: 484 GSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEF 543 V ++S GL ++VLL + + I KWR+++ LG + +LY +FL S+M+E Sbjct: 1031 LQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLED 1090 Query: 544 NVFT 547 + + Sbjct: 1091 RIIS 1094 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%) Query: 64 KICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 123 ++ E + +SE++ G T +AAG+S P+L SVI GD+ V + VGS +F+I + V Sbjct: 961 QVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPV 1020 Query: 124 CGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIV--WWE-----GLVLIILYVF 176 L + L V + ++ I ++ L++ I W G + +LY Sbjct: 1021 PWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFV 1080 Query: 177 YILI 180 +++I Sbjct: 1081 FLII 1084 Score = 38.5 bits (88), Expect = 0.016 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Query: 389 FMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQ 448 F + ++ L I Y + L +I L I + + G TF+AAG S P+ SLI Sbjct: 460 FGMMYVFVALAIVCDEYFVPAL-GVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 518 Query: 449 GLGDMAVSNTIGSNVFDILVGLG 471 ++ + +GS VF+IL +G Sbjct: 519 SHSNVGIGTIVGSAVFNILFVIG 541 >gi|45504369 solute carrier family 24, member 5 [Homo sapiens] Length = 500 Score = 203 bits (516), Expect = 4e-52 Identities = 95/203 (46%), Positives = 139/203 (68%), Gaps = 1/203 (0%) Query: 343 VEADFLSPFSVPEARGDKVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAV 402 V D S F++PEA ++ WV + P+I LL +T P+C K W+ +F++TF + +WI+ Sbjct: 288 VSEDPPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISA 347 Query: 403 FSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSN 462 F+YI+VW+VTI G TL IPD +MG+T LAAGTS+PD +AS++VAR+G GDMA+SN +GSN Sbjct: 348 FTYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSN 407 Query: 463 VFDILVGLGVPWGLQTMVVNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRK 522 VFD+L LG+PW ++T +N + ++NSRGL Y + L S+ L +H N W+LDRK Sbjct: 408 VFDMLC-LGIPWFIKTAFINGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRK 466 Query: 523 LGVYVLVLYAIFLCFSIMIEFNV 545 LG+ L+ Y S++ E + Sbjct: 467 LGIVCLLSYLGLATLSVLYELGI 489 Score = 185 bits (470), Expect = 8e-47 Identities = 103/282 (36%), Positives = 150/282 (53%), Gaps = 42/282 (14%) Query: 7 TQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKIC 66 T + C EFP F+ +ER+ G ++++ L +YMF A++IVCD++F+PSLE I Sbjct: 40 TGNSTQCVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIIS 99 Query: 67 ERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGL 126 E L LS+DVAG TFMAAGSS PEL + +GVFIT GD+G+ TI+GSA++N+L I CGL Sbjct: 100 ESLGLSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGL 159 Query: 127 FAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVK 186 + V L+ W + RD YTIS ++ IYD Q+ W+EG +L+++Y Y+L++ +++K Sbjct: 160 LSNTVSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIK 219 Query: 187 MQAFFTVKQKSIA--------------------NGNPV---NSELEAGNDFYDGSYDDPS 223 + + K G P S ++G + D Y S Sbjct: 220 INQYIIKKCSPCCACLAKAMERSEQQPLMGWEDEGQPFIRRQSRTDSGIFYEDSGYSQLS 279 Query: 224 VPL--LGQVKEKPQYGKNPVVMVDEIMSSSPPKFTFPEAGLR 263 + L L QV E P P F PEA L+ Sbjct: 280 ISLHGLSQVSEDP-----------------PSVFNMPEADLK 304 Score = 50.1 bits (118), Expect = 5e-06 Identities = 41/156 (26%), Positives = 75/156 (48%), Gaps = 10/156 (6%) Query: 388 FFMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVAR 447 F ++ ++ + I Y + L II +LG+ + G TF+AAG+S P+ + + + Sbjct: 73 FLIIVYMFMAISIVCDEYFLPSL-EIISESLGLSQDVAGTTFMAAGSSAPELVTAFLGVF 131 Query: 448 QGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNYGSTVKINSRGLVYSVVLLLGSVAL 507 GD+ +S +GS ++++L G+ GL + V+ S + Y++ A Sbjct: 132 ITKGDIGISTILGSAIYNLL-GICAACGLLSNTVSTLSCWPLFRDCAAYTI------SAA 184 Query: 508 TVLGIHLNK--WRLDRKLGVYVLVLYAIFLCFSIMI 541 VLGI + + + L + + LY + LCF I I Sbjct: 185 AVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKI 220 Score = 49.3 bits (116), Expect = 9e-06 Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Query: 67 ERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGL 126 E L + + V G T +AAG+S P+ ASV+ GD+ + IVGS VF++LC +G+ Sbjct: 361 ETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDMLC-LGIPWF 419 Query: 127 FAGQVVRLTWWAV--CRDSVYYTISVIVLIVFIY 158 + + A R Y TIS+ + I+F++ Sbjct: 420 IKTAFINGSAPAEVNSRGLTYITISLNISIIFLF 453 >gi|39995086 solute carrier family 24 member 6 [Homo sapiens] Length = 584 Score = 76.6 bits (187), Expect = 5e-14 Identities = 49/160 (30%), Positives = 86/160 (53%), Gaps = 4/160 (2%) Query: 388 FFMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVAR 447 F + F+T+ LWI + +V ++ +G + + ++G+T LA G S+ D + +AR Sbjct: 421 FAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLAR 480 Query: 448 QGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNYGSTVKINSRG-LVYSVVLLLG-SV 505 QG MA S G +F+ILVG+G+ G + + VK+ G LV+ + LG S+ Sbjct: 481 QGYPRMAFSACFGGIIFNILVGVGL--GCLLQISRSHTEVKLEPDGLLVWVLAGALGLSL 538 Query: 506 ALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEFNV 545 +++ + L ++L R G +L+ Y FL +++ EF V Sbjct: 539 VFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGV 578 Score = 68.9 bits (167), Expect = 1e-11 Identities = 41/146 (28%), Positives = 73/146 (50%), Gaps = 3/146 (2%) Query: 35 AVLLHILGALYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASV 94 AV L++ LY+F L + FF P+L I L LS +VAG TF+A G+ P++F+++ Sbjct: 99 AVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSAL 158 Query: 95 IGVFITH-GDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVL 153 + H + +G + G+ V + G G+ RD V+Y ++V + Sbjct: 159 VAFSDPHTAGLALGALFGAGVLVTTVVAG--GITILHPFMAASRPFFRDIVFYMVAVFLT 216 Query: 154 IVFIYDEQIVWWEGLVLIILYVFYIL 179 + ++ ++ L + LYVFY++ Sbjct: 217 FLMLFRGRVTLAWALGYLGLYVFYVV 242 Score = 37.7 bits (86), Expect = 0.028 Identities = 43/162 (26%), Positives = 68/162 (41%), Gaps = 31/162 (19%) Query: 394 ITATLWIAVFSYIMVWL-----------VTIIGYTLGIPDVIMGITFLAAGTSVPDCMAS 442 + TL+++ Y+ + L ++ I TL + + G+TFLA G PD ++ Sbjct: 98 LAVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSA 157 Query: 443 LIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNYGSTV----KINSRGLVYSV 498 L+ + +T G L G GV L T VV G T+ SR + Sbjct: 158 LVA-------FSDPHTAGL-ALGALFGAGV---LVTTVVAGGITILHPFMAASRPFFRDI 206 Query: 499 VLLLGSVALTVLGIHLNK----WRLDRKLGVYVLVLYAIFLC 536 V + +V LT L + + W L LG+YV + + LC Sbjct: 207 VFYMVAVFLTFLMLFRGRVTLAWALG-YLGLYVFYVVTVILC 247 >gi|10863913 solute carrier family 8 (sodium/calcium exchanger), member 1 isoform A [Homo sapiens] Length = 973 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 451 FI + L I + + + L + G T+G+ D + + F+A GTSVPD AS + A Q Sbjct: 804 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 863 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 500 D ++ N GSN ++ +G+GV W + + G K++ L +SV L Sbjct: 864 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 913 Score = 55.8 bits (133), Expect = 1e-07 Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 28/164 (17%) Query: 38 LHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 79 ++ + +YMF ++I+ D F + S+E I + +E V+ T Sbjct: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138 Query: 80 FMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQVVRL 134 MA GSS PE+ SVI V T GD+G TIVGSA FN+ II +C G+ ++ Sbjct: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198 Query: 135 ----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 174 ++ S++ + +++ I + WEGL+ + Sbjct: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFF 242 Score = 36.6 bits (83), Expect = 0.062 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 3/90 (3%) Query: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS V + D +G + GS N+ IGV A Sbjct: 831 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 890 Query: 130 --QVVRLTWWAVCRDSVYYTISVIVLIVFI 157 + V ++ +++++ + FI Sbjct: 891 IYHAANGEQFKVSPGTLAFSVTLFTIFAFI 920 >gi|163914373 solute carrier family 8 (sodium/calcium exchanger), member 1 isoform D [Homo sapiens] Length = 937 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 451 FI + L I + + + L + G T+G+ D + + F+A GTSVPD AS + A Q Sbjct: 768 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 827 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 500 D ++ N GSN ++ +G+GV W + + G K++ L +SV L Sbjct: 828 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 877 Score = 55.8 bits (133), Expect = 1e-07 Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 28/164 (17%) Query: 38 LHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 79 ++ + +YMF ++I+ D F + S+E I + +E V+ T Sbjct: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138 Query: 80 FMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQVVRL 134 MA GSS PE+ SVI V T GD+G TIVGSA FN+ II +C G+ ++ Sbjct: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198 Query: 135 ----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 174 ++ S++ + +++ I + WEGL+ + Sbjct: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFF 242 Score = 36.6 bits (83), Expect = 0.062 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 3/90 (3%) Query: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS V + D +G + GS N+ IGV A Sbjct: 795 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 854 Query: 130 --QVVRLTWWAVCRDSVYYTISVIVLIVFI 157 + V ++ +++++ + FI Sbjct: 855 IYHAANGEQFKVSPGTLAFSVTLFTIFAFI 884 >gi|163914371 solute carrier family 8 (sodium/calcium exchanger), member 1 isoform C [Homo sapiens] Length = 960 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 451 FI + L I + + + L + G T+G+ D + + F+A GTSVPD AS + A Q Sbjct: 791 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 850 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 500 D ++ N GSN ++ +G+GV W + + G K++ L +SV L Sbjct: 851 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 900 Score = 55.8 bits (133), Expect = 1e-07 Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 28/164 (17%) Query: 38 LHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 79 ++ + +YMF ++I+ D F + S+E I + +E V+ T Sbjct: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138 Query: 80 FMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQVVRL 134 MA GSS PE+ SVI V T GD+G TIVGSA FN+ II +C G+ ++ Sbjct: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198 Query: 135 ----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 174 ++ S++ + +++ I + WEGL+ + Sbjct: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFF 242 Score = 36.6 bits (83), Expect = 0.062 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 3/90 (3%) Query: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS V + D +G + GS N+ IGV A Sbjct: 818 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 877 Query: 130 --QVVRLTWWAVCRDSVYYTISVIVLIVFI 157 + V ++ +++++ + FI Sbjct: 878 IYHAANGEQFKVSPGTLAFSVTLFTIFAFI 907 >gi|163914369 solute carrier family 8 (sodium/calcium exchanger), member 1 isoform B [Homo sapiens] Length = 968 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 451 FI + L I + + + L + G T+G+ D + + F+A GTSVPD AS + A Q Sbjct: 799 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 858 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 500 D ++ N GSN ++ +G+GV W + + G K++ L +SV L Sbjct: 859 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 908 Score = 55.8 bits (133), Expect = 1e-07 Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 28/164 (17%) Query: 38 LHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 79 ++ + +YMF ++I+ D F + S+E I + +E V+ T Sbjct: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138 Query: 80 FMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQVVRL 134 MA GSS PE+ SVI V T GD+G TIVGSA FN+ II +C G+ ++ Sbjct: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198 Query: 135 ----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 174 ++ S++ + +++ I + WEGL+ + Sbjct: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFF 242 Score = 36.6 bits (83), Expect = 0.062 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 3/90 (3%) Query: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS V + D +G + GS N+ IGV A Sbjct: 826 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 885 Query: 130 --QVVRLTWWAVCRDSVYYTISVIVLIVFI 157 + V ++ +++++ + FI Sbjct: 886 IYHAANGEQFKVSPGTLAFSVTLFTIFAFI 915 >gi|17865805 solute carrier family 8 (sodium/calcium exchanger), member 3 isoform B precursor [Homo sapiens] Length = 924 Score = 62.8 bits (151), Expect = 8e-10 Identities = 65/262 (24%), Positives = 115/262 (43%), Gaps = 51/262 (19%) Query: 36 VLLHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAG 77 V+++ + +YMF ++I+ D F S+E I + +E V+ Sbjct: 77 VIVYFVALIYMFLGVSIIADRFMA-SIEVITSQEREVTIKKPNGETSTTTIRVWNETVSN 135 Query: 78 ATFMAAGSSTPELFASVIGV----FITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQV 131 T MA GSS PE+ S+I V FI GD+G TIVGSA FN+ IIG+C G+ Sbjct: 136 LTLMALGSSAPEILLSLIEVCGHGFIA-GDLGPSTIVGSAAFNMFIIIGICVYVIPDGET 194 Query: 132 VRL----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYIL-------- 179 ++ ++ S++ I + +++ + WEGL+ + + +L Sbjct: 195 RKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKR 254 Query: 180 IMKYNVKMQAFFTVKQKSI----ANGNPVNSELEA---GNDFYDGSYDDPSVPLLGQVKE 232 ++ Y + + T K + I +P E++ + F DG+ VPL G KE Sbjct: 255 LLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGNL----VPLEG--KE 308 Query: 233 KPQYGKNPVVMVDEIMSSSPPK 254 + + + ++ ++ P K Sbjct: 309 VDESRREMIRILKDLKQKHPEK 330 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 4/122 (3%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGL-G 451 F + L I + + I+ L + G T+G+ D + + F+A GTSVPD AS A Q + Sbjct: 755 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 814 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL--LLGSVALT 508 D ++ N GSN ++ +G+G+ W + + G +++ L +SV L + V ++ Sbjct: 815 DASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCIS 874 Query: 509 VL 510 VL Sbjct: 875 VL 876 Score = 35.4 bits (80), Expect = 0.14 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 11/94 (11%) Query: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS + + D +G + GS N+ IG+ A Sbjct: 782 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL----AW 837 Query: 130 QVVRLTW------WAVCRDSVYYTISVIVLIVFI 157 V + W + V ++ +++++ + F+ Sbjct: 838 SVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFV 871 Score = 33.5 bits (75), Expect = 0.53 Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 3/54 (5%) Query: 422 DVIMGITFLAAGTSVPDCMASLI-VARQGL--GDMAVSNTIGSNVFDILVGLGV 472 + + +T +A G+S P+ + SLI V G GD+ S +GS F++ + +G+ Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184 >gi|33946304 solute carrier family 8 (sodium/calcium exchanger), member 3 isoform D precursor [Homo sapiens] Length = 921 Score = 62.8 bits (151), Expect = 8e-10 Identities = 65/262 (24%), Positives = 115/262 (43%), Gaps = 51/262 (19%) Query: 36 VLLHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAG 77 V+++ + +YMF ++I+ D F S+E I + +E V+ Sbjct: 77 VIVYFVALIYMFLGVSIIADRFMA-SIEVITSQEREVTIKKPNGETSTTTIRVWNETVSN 135 Query: 78 ATFMAAGSSTPELFASVIGV----FITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQV 131 T MA GSS PE+ S+I V FI GD+G TIVGSA FN+ IIG+C G+ Sbjct: 136 LTLMALGSSAPEILLSLIEVCGHGFIA-GDLGPSTIVGSAAFNMFIIIGICVYVIPDGET 194 Query: 132 VRL----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYIL-------- 179 ++ ++ S++ I + +++ + WEGL+ + + +L Sbjct: 195 RKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKR 254 Query: 180 IMKYNVKMQAFFTVKQKSI----ANGNPVNSELEA---GNDFYDGSYDDPSVPLLGQVKE 232 ++ Y + + T K + I +P E++ + F DG+ VPL G KE Sbjct: 255 LLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGNL----VPLEG--KE 308 Query: 233 KPQYGKNPVVMVDEIMSSSPPK 254 + + + ++ ++ P K Sbjct: 309 VDESRREMIRILKDLKQKHPEK 330 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 4/122 (3%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGL-G 451 F + L I + + I+ L + G T+G+ D + + F+A GTSVPD AS A Q + Sbjct: 752 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 811 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL--LLGSVALT 508 D ++ N GSN ++ +G+G+ W + + G +++ L +SV L + V ++ Sbjct: 812 DASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCIS 871 Query: 509 VL 510 VL Sbjct: 872 VL 873 Score = 35.4 bits (80), Expect = 0.14 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 11/94 (11%) Query: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS + + D +G + GS N+ IG+ A Sbjct: 779 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL----AW 834 Query: 130 QVVRLTW------WAVCRDSVYYTISVIVLIVFI 157 V + W + V ++ +++++ + F+ Sbjct: 835 SVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFV 868 Score = 33.5 bits (75), Expect = 0.53 Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 3/54 (5%) Query: 422 DVIMGITFLAAGTSVPDCMASLI-VARQGL--GDMAVSNTIGSNVFDILVGLGV 472 + + +T +A G+S P+ + SLI V G GD+ S +GS F++ + +G+ Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184 >gi|15147254 solute carrier family 8 (sodium/calcium exchanger), member 3 isoform A precursor [Homo sapiens] Length = 925 Score = 62.8 bits (151), Expect = 8e-10 Identities = 65/262 (24%), Positives = 115/262 (43%), Gaps = 51/262 (19%) Query: 36 VLLHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAG 77 V+++ + +YMF ++I+ D F S+E I + +E V+ Sbjct: 77 VIVYFVALIYMFLGVSIIADRFMA-SIEVITSQEREVTIKKPNGETSTTTIRVWNETVSN 135 Query: 78 ATFMAAGSSTPELFASVIGV----FITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQV 131 T MA GSS PE+ S+I V FI GD+G TIVGSA FN+ IIG+C G+ Sbjct: 136 LTLMALGSSAPEILLSLIEVCGHGFIA-GDLGPSTIVGSAAFNMFIIIGICVYVIPDGET 194 Query: 132 VRL----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYIL-------- 179 ++ ++ S++ I + +++ + WEGL+ + + +L Sbjct: 195 RKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKR 254 Query: 180 IMKYNVKMQAFFTVKQKSI----ANGNPVNSELEA---GNDFYDGSYDDPSVPLLGQVKE 232 ++ Y + + T K + I +P E++ + F DG+ VPL G KE Sbjct: 255 LLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGNL----VPLEG--KE 308 Query: 233 KPQYGKNPVVMVDEIMSSSPPK 254 + + + ++ ++ P K Sbjct: 309 VDESRREMIRILKDLKQKHPEK 330 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 4/122 (3%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGL-G 451 F + L I + + I+ L + G T+G+ D + + F+A GTSVPD AS A Q + Sbjct: 756 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 815 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL--LLGSVALT 508 D ++ N GSN ++ +G+G+ W + + G +++ L +SV L + V ++ Sbjct: 816 DASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCIS 875 Query: 509 VL 510 VL Sbjct: 876 VL 877 Score = 35.4 bits (80), Expect = 0.14 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 11/94 (11%) Query: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS + + D +G + GS N+ IG+ A Sbjct: 783 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL----AW 838 Query: 130 QVVRLTW------WAVCRDSVYYTISVIVLIVFI 157 V + W + V ++ +++++ + F+ Sbjct: 839 SVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFV 872 Score = 33.5 bits (75), Expect = 0.53 Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 3/54 (5%) Query: 422 DVIMGITFLAAGTSVPDCMASLI-VARQGL--GDMAVSNTIGSNVFDILVGLGV 472 + + +T +A G+S P+ + SLI V G GD+ S +GS F++ + +G+ Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184 >gi|33946311 solute carrier family 8 (sodium/calcium exchanger), member 3 isoform C precursor [Homo sapiens] Length = 927 Score = 62.8 bits (151), Expect = 8e-10 Identities = 65/262 (24%), Positives = 115/262 (43%), Gaps = 51/262 (19%) Query: 36 VLLHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAG 77 V+++ + +YMF ++I+ D F S+E I + +E V+ Sbjct: 77 VIVYFVALIYMFLGVSIIADRFMA-SIEVITSQEREVTIKKPNGETSTTTIRVWNETVSN 135 Query: 78 ATFMAAGSSTPELFASVIGV----FITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQV 131 T MA GSS PE+ S+I V FI GD+G TIVGSA FN+ IIG+C G+ Sbjct: 136 LTLMALGSSAPEILLSLIEVCGHGFIA-GDLGPSTIVGSAAFNMFIIIGICVYVIPDGET 194 Query: 132 VRL----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYIL-------- 179 ++ ++ S++ I + +++ + WEGL+ + + +L Sbjct: 195 RKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKR 254 Query: 180 IMKYNVKMQAFFTVKQKSI----ANGNPVNSELEA---GNDFYDGSYDDPSVPLLGQVKE 232 ++ Y + + T K + I +P E++ + F DG+ VPL G KE Sbjct: 255 LLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGNL----VPLEG--KE 308 Query: 233 KPQYGKNPVVMVDEIMSSSPPK 254 + + + ++ ++ P K Sbjct: 309 VDESRREMIRILKDLKQKHPEK 330 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 4/122 (3%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGL-G 451 F + L I + + I+ L + G T+G+ D + + F+A GTSVPD AS A Q + Sbjct: 758 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 817 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL--LLGSVALT 508 D ++ N GSN ++ +G+G+ W + + G +++ L +SV L + V ++ Sbjct: 818 DASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCIS 877 Query: 509 VL 510 VL Sbjct: 878 VL 879 Score = 35.4 bits (80), Expect = 0.14 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 11/94 (11%) Query: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS + + D +G + GS N+ IG+ A Sbjct: 785 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL----AW 840 Query: 130 QVVRLTW------WAVCRDSVYYTISVIVLIVFI 157 V + W + V ++ +++++ + F+ Sbjct: 841 SVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFV 874 Score = 33.5 bits (75), Expect = 0.53 Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 3/54 (5%) Query: 422 DVIMGITFLAAGTSVPDCMASLI-VARQGL--GDMAVSNTIGSNVFDILVGLGV 472 + + +T +A G+S P+ + SLI V G GD+ S +GS F++ + +G+ Sbjct: 131 ETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFIIIGI 184 >gi|33946308 solute carrier family 8 (sodium/calcium exchanger), member 3 isoform F [Homo sapiens] Length = 284 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 4/122 (3%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGL-G 451 F + L I + + I+ L + G T+G+ D + + F+A GTSVPD AS A Q + Sbjct: 115 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 174 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL--LLGSVALT 508 D ++ N GSN ++ +G+G+ W + + G +++ L +SV L + V ++ Sbjct: 175 DASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCIS 234 Query: 509 VL 510 VL Sbjct: 235 VL 236 Score = 35.4 bits (80), Expect = 0.14 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 11/94 (11%) Query: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS + + D +G + GS N+ IG+ A Sbjct: 142 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL----AW 197 Query: 130 QVVRLTW------WAVCRDSVYYTISVIVLIVFI 157 V + W + V ++ +++++ + F+ Sbjct: 198 SVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFV 231 >gi|194354001 solute carrier family 8 (sodium/calcium exchanger), member 3 isoform G [Homo sapiens] Length = 298 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 4/122 (3%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGL-G 451 F + L I + + I+ L + G T+G+ D + + F+A GTSVPD AS A Q + Sbjct: 129 FAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYA 188 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL--LLGSVALT 508 D ++ N GSN ++ +G+G+ W + + G +++ L +SV L + V ++ Sbjct: 189 DASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCIS 248 Query: 509 VL 510 VL Sbjct: 249 VL 250 Score = 35.4 bits (80), Expect = 0.14 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 11/94 (11%) Query: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS + + D +G + GS N+ IG+ A Sbjct: 156 LKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGL----AW 211 Query: 130 QVVRLTW------WAVCRDSVYYTISVIVLIVFI 157 V + W + V ++ +++++ + F+ Sbjct: 212 SVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFV 245 >gi|57163987 solute carrier family 8 member 2 [Homo sapiens] Length = 921 Score = 59.7 bits (143), Expect = 7e-09 Identities = 34/110 (30%), Positives = 58/110 (52%), Gaps = 2/110 (1%) Query: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 451 F + L I + + ++ L + G T+G+ D + + F+A GTS+PD AS + A Q Sbjct: 752 FGVSILVIGLLTALIGDLASHFGCTVGLKDSVNAVVFVALGTSIPDTFASKVAALQDQCA 811 Query: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 500 D ++ N GSN ++ +GLGV W + + G ++ + L +SV L Sbjct: 812 DASIGNVTGSNAVNVFLGLGVAWSVAAVYWAVQGRPFEVRTGTLAFSVTL 861 Score = 56.2 bits (134), Expect = 8e-08 Identities = 47/165 (28%), Positives = 80/165 (48%), Gaps = 28/165 (16%) Query: 37 LLHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGA 78 +++ + +YMF ++I+ D F ++E I + +E V+ Sbjct: 73 VVYFVAMVYMFLGVSIIADRFMA-AIEVITSKEKEITITKANGETSVGTVRIWNETVSNL 131 Query: 79 TFMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVC--GLFAGQVVR 133 T MA GSS PE+ SVI V G++G GTIVGSA FN+ +I VC + AG+ + Sbjct: 132 TLMALGSSAPEILLSVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVCIYVIPAGESRK 191 Query: 134 LTWWAVCRDSVYYTISVIV---LIVFIYDEQIVW-WEGLVLIILY 174 + V + ++I V LI+ ++ +V WE L+ ++ + Sbjct: 192 IKHLRVFFVTASWSIFAYVWLYLILAVFSPGVVQVWEALLTLVFF 236 Score = 35.4 bits (80), Expect = 0.14 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 6/70 (8%) Query: 71 LSEDVAGATFMAAGSSTPELFASVIGVFITH-GDVGVGTIVGSAVFNILCIIGVCGLFAG 129 L + V F+A G+S P+ FAS + D +G + GS N+ +GV A Sbjct: 779 LKDSVNAVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAA 838 Query: 130 QVVRLTWWAV 139 +WAV Sbjct: 839 -----VYWAV 843 >gi|62000702 diacylglycerol kinase kappa [Homo sapiens] Length = 1271 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 9/67 (13%) Query: 311 ENGNVPVENPEDPQQNQEQQPPPQPPP---------PEPEPVEADFLSPFSVPEARGDKV 361 ++G P E+PE P PPP PPP PEP P L+P PEA + Sbjct: 15 QDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESA 74 Query: 362 KWVFTWP 368 ++T P Sbjct: 75 TELYTEP 81 Score = 37.0 bits (84), Expect = 0.048 Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 4/47 (8%) Query: 313 GNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFL----SPFSVPE 355 G P ++ E P ++ E PP PPPP P P A L SP +PE Sbjct: 10 GTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPE 56 Score = 29.3 bits (64), Expect = 10.0 Identities = 10/33 (30%), Positives = 16/33 (48%) Query: 310 IENGNVPVENPEDPQQNQEQQPPPQPPPPEPEP 342 ++ G + PQ ++ P+PPPP P P Sbjct: 1 MDRGAAAAQGTAPPQDGEQPAESPEPPPPWPPP 33 >gi|8923842 forkhead box J2 [Homo sapiens] Length = 574 Score = 40.0 bits (92), Expect = 0.006 Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 2/41 (4%) Query: 318 ENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARG 358 + P PQQ Q+QQ PPQPPP + +P + +P P A G Sbjct: 293 QQPPPPQQQQQQQQPPQPPPQQSQPQQQQ--APAQGPSAVG 331 >gi|5730045 solute carrier family 16, member 2 [Homo sapiens] Length = 613 Score = 39.3 bits (90), Expect = 0.010 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 14/110 (12%) Query: 249 SSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSKPLQNGRHE 308 SSSPP + + NK+ P++ S L + A+ + P Q E Sbjct: 42 SSSPPSSSSCSS------RNKYQPQSGSSGPSSHSPPAAMALQSQASEEAKGPWQEADQE 95 Query: 309 NIENGNVPVENPEDPQQNQEQQPPPQP---PPPEPEPVEADFLSPFSVPE 355 E PV +PE P+ E +P P+P PPPEP+P P +PE Sbjct: 96 QQE----PVGSPE-PESEPEPEPEPEPVPVPPPEPQPEPQPLPDPAPLPE 140 >gi|32307177 forkhead box G1 [Homo sapiens] Length = 489 Score = 39.3 bits (90), Expect = 0.010 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 303 QNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEP 342 Q+ H + + + P P+ P Q+QQPPP PPPP P+P Sbjct: 46 QHHHHHHHHHHHPPPPAPQPPPPPQQQQPPP-PPPPAPQP 84 >gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 38.5 bits (88), Expect = 0.016 Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 2/40 (5%) Query: 316 PVENPEDPQQNQEQQPPPQP--PPPEPEPVEADFLSPFSV 353 P P PQQ +QQP PQP PPP P P + LS S+ Sbjct: 1668 PAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSM 1707 Score = 35.8 bits (81), Expect = 0.11 Identities = 16/29 (55%), Positives = 18/29 (62%), Gaps = 4/29 (13%) Query: 321 EDPQQNQEQQPPPQPP----PPEPEPVEA 345 E P NQ+QQPPP PP PP P+P A Sbjct: 1641 ERPPSNQQQQPPPPPPQQPQPPPPQPQPA 1669 Score = 33.9 bits (76), Expect = 0.40 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Query: 276 LRMASRIIINERQRLINSANGVSSKPLQNGRHENIENG-NVPVENPEDPQQNQEQQPPPQ 334 L +S ++ + + +S + + +Q + +I++ + VE P QQ Q PPPQ Sbjct: 1598 LTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQ 1657 Query: 335 P---PPPEPEP 342 PPP+P+P Sbjct: 1658 QPQPPPPQPQP 1668 Score = 32.7 bits (73), Expect = 0.90 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%) Query: 320 PEDPQQNQ----EQQPPPQPPPPEPEPVEADFLSPFSVP 354 P PQQ Q + QP PQPPPP+ +P + P P Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPP 1691 Score = 31.2 bits (69), Expect = 2.6 Identities = 13/26 (50%), Positives = 15/26 (57%), Gaps = 1/26 (3%) Query: 318 ENPEDPQQNQEQQPPPQP-PPPEPEP 342 + P P Q Q PPPQP P P+P P Sbjct: 1649 QQPPPPPPQQPQPPPPQPQPAPQPPP 1674 >gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 38.5 bits (88), Expect = 0.016 Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 2/40 (5%) Query: 316 PVENPEDPQQNQEQQPPPQP--PPPEPEPVEADFLSPFSV 353 P P PQQ +QQP PQP PPP P P + LS S+ Sbjct: 1668 PAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSM 1707 Score = 35.8 bits (81), Expect = 0.11 Identities = 16/29 (55%), Positives = 18/29 (62%), Gaps = 4/29 (13%) Query: 321 EDPQQNQEQQPPPQPP----PPEPEPVEA 345 E P NQ+QQPPP PP PP P+P A Sbjct: 1641 ERPPSNQQQQPPPPPPQQPQPPPPQPQPA 1669 Score = 33.9 bits (76), Expect = 0.40 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Query: 276 LRMASRIIINERQRLINSANGVSSKPLQNGRHENIENG-NVPVENPEDPQQNQEQQPPPQ 334 L +S ++ + + +S + + +Q + +I++ + VE P QQ Q PPPQ Sbjct: 1598 LTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQ 1657 Query: 335 P---PPPEPEP 342 PPP+P+P Sbjct: 1658 QPQPPPPQPQP 1668 Score = 32.7 bits (73), Expect = 0.90 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%) Query: 320 PEDPQQNQ----EQQPPPQPPPPEPEPVEADFLSPFSVP 354 P PQQ Q + QP PQPPPP+ +P + P P Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPP 1691 Score = 31.2 bits (69), Expect = 2.6 Identities = 13/26 (50%), Positives = 15/26 (57%), Gaps = 1/26 (3%) Query: 318 ENPEDPQQNQEQQPPPQP-PPPEPEP 342 + P P Q Q PPPQP P P+P P Sbjct: 1649 QQPPPPPPQQPQPPPPQPQPAPQPPP 1674 >gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 38.5 bits (88), Expect = 0.016 Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 2/40 (5%) Query: 316 PVENPEDPQQNQEQQPPPQP--PPPEPEPVEADFLSPFSV 353 P P PQQ +QQP PQP PPP P P + LS S+ Sbjct: 1668 PAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSM 1707 Score = 35.8 bits (81), Expect = 0.11 Identities = 16/29 (55%), Positives = 18/29 (62%), Gaps = 4/29 (13%) Query: 321 EDPQQNQEQQPPPQPP----PPEPEPVEA 345 E P NQ+QQPPP PP PP P+P A Sbjct: 1641 ERPPSNQQQQPPPPPPQQPQPPPPQPQPA 1669 Score = 33.9 bits (76), Expect = 0.40 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Query: 276 LRMASRIIINERQRLINSANGVSSKPLQNGRHENIENG-NVPVENPEDPQQNQEQQPPPQ 334 L +S ++ + + +S + + +Q + +I++ + VE P QQ Q PPPQ Sbjct: 1598 LTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQ 1657 Query: 335 P---PPPEPEP 342 PPP+P+P Sbjct: 1658 QPQPPPPQPQP 1668 Score = 32.7 bits (73), Expect = 0.90 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 4/39 (10%) Query: 320 PEDPQQNQ----EQQPPPQPPPPEPEPVEADFLSPFSVP 354 P PQQ Q + QP PQPPPP+ +P + P P Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPP 1691 Score = 31.2 bits (69), Expect = 2.6 Identities = 13/26 (50%), Positives = 15/26 (57%), Gaps = 1/26 (3%) Query: 318 ENPEDPQQNQEQQPPPQP-PPPEPEP 342 + P P Q Q PPPQP P P+P P Sbjct: 1649 QQPPPPPPQQPQPPPPQPQPAPQPPP 1674 >gi|169636435 caudal type homeobox 2 [Homo sapiens] Length = 313 Score = 38.1 bits (87), Expect = 0.021 Identities = 17/31 (54%), Positives = 20/31 (64%) Query: 325 QNQEQQPPPQPPPPEPEPVEADFLSPFSVPE 355 Q Q+QQ PPQPPPP P+P + SVPE Sbjct: 250 QQQQQQQPPQPPPPPPQPPQPQPGPLRSVPE 280 Score = 37.0 bits (84), Expect = 0.048 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 6/83 (7%) Query: 280 SRIIINERQRLINSANGVSSKPL----QNGRHENIENGNVPVENPEDPQQNQEQQPPPQP 335 SR I R+ + + G+S + + QN R + + ++ + Q Q PPPQP Sbjct: 208 SRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQP 267 Query: 336 PPPEPEPVEA--DFLSPFSVPEA 356 P P+P P+ + + LSP S +A Sbjct: 268 PQPQPGPLRSVPEPLSPVSSLQA 290 >gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens] Length = 429 Score = 37.7 bits (86), Expect = 0.028 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 11/68 (16%) Query: 275 RLRMASRIIINERQRLINSANGVSSKPLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQ 334 +L S + IN Q + + S+P+ R +G + QQ Q+QQ PP Sbjct: 307 QLSQGSNLSINTNQNI-----SIKSEPISPPRDRMTPSGF------QQQQQQQQQQQPPP 355 Query: 335 PPPPEPEP 342 PP P+P+P Sbjct: 356 PPQPQPQP 363 >gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens] Length = 437 Score = 37.7 bits (86), Expect = 0.028 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 11/68 (16%) Query: 275 RLRMASRIIINERQRLINSANGVSSKPLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQ 334 +L S + IN Q + + S+P+ R +G + QQ Q+QQ PP Sbjct: 315 QLSQGSNLSINTNQNI-----SIKSEPISPPRDRMTPSGF------QQQQQQQQQQQPPP 363 Query: 335 PPPPEPEP 342 PP P+P+P Sbjct: 364 PPQPQPQP 371 >gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens] Length = 497 Score = 37.7 bits (86), Expect = 0.028 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 11/68 (16%) Query: 275 RLRMASRIIINERQRLINSANGVSSKPLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQ 334 +L S + IN Q + + S+P+ R +G + QQ Q+QQ PP Sbjct: 375 QLSQGSNLSINTNQNI-----SIKSEPISPPRDRMTPSGF------QQQQQQQQQQQPPP 423 Query: 335 PPPPEPEP 342 PP P+P+P Sbjct: 424 PPQPQPQP 431 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.141 0.439 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,299,116 Number of Sequences: 37866 Number of extensions: 1131182 Number of successful extensions: 17758 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 235 Number of HSP's successfully gapped in prelim test: 126 Number of HSP's that attempted gapping in prelim test: 13163 Number of HSP's gapped (non-prelim): 3111 length of query: 558 length of database: 18,247,518 effective HSP length: 107 effective length of query: 451 effective length of database: 14,195,856 effective search space: 6402331056 effective search space used: 6402331056 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.