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Search of human proteins with 29568103
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
(437 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 909 0.0
gi|13027642 small nuclear ribonucleoprotein 35kDa (U11/U12) isof... 151 1e-36
gi|31077198 small nuclear ribonucleoprotein 35kDa (U11/U12) isof... 151 1e-36
gi|31077200 small nuclear ribonucleoprotein 35kDa (U11/U12) isof... 151 1e-36
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 117 2e-26
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 113 3e-25
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 108 7e-24
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 104 1e-22
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 103 2e-22
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 103 2e-22
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 101 1e-21
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 101 2e-21
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 100 2e-21
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 98 2e-20
gi|52426743 cisplatin resistance-associated overexpressed protei... 96 5e-20
gi|19923485 cisplatin resistance-associated overexpressed protei... 96 5e-20
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 96 8e-20
gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso... 92 9e-19
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 90 4e-18
gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens] 90 5e-18
gi|9558733 transformer-2 alpha [Homo sapiens] 89 1e-17
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 88 2e-17
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 86 7e-17
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 83 4e-16
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 83 6e-16
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] 82 7e-16
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 82 1e-15
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 82 1e-15
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 80 3e-15
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 80 4e-15
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 909 bits (2349), Expect = 0.0
Identities = 437/437 (100%), Positives = 437/437 (100%)
Query: 1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRA 60
MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRA
Sbjct: 1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRA 60
Query: 61 ETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLR 120
ETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLR
Sbjct: 61 ETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLR 120
Query: 121 REFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVER 180
REFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVER
Sbjct: 121 REFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVER 180
Query: 181 GRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERE 240
GRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERE
Sbjct: 181 GRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERE 240
Query: 241 RRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERAR 300
RRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERAR
Sbjct: 241 RRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERAR 300
Query: 301 RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRS 360
RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRS
Sbjct: 301 RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRS 360
Query: 361 ERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESEGG 420
ERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESEGG
Sbjct: 361 ERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESEGG 420
Query: 421 DGYLAPENGYLMEAAPE 437
DGYLAPENGYLMEAAPE
Sbjct: 421 DGYLAPENGYLMEAAPE 437
>gi|13027642 small nuclear ribonucleoprotein 35kDa (U11/U12) isoform
a [Homo sapiens]
Length = 246
Score = 151 bits (382), Expect = 1e-36
Identities = 90/206 (43%), Positives = 120/206 (58%), Gaps = 9/206 (4%)
Query: 99 GDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMH 158
GD TLFVAR+N T E KL+ F YG I+R+ +V +G +GYAFIEY+ ER +
Sbjct: 47 GDPLLTLFVARLNLQTKEDKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEERAVI 106
Query: 159 SAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSR 218
AY+ ADG ID + VD E RT+KGW PRRLGGGLGG + G +R GRD R
Sbjct: 107 KAYRDADGLVIDQHEIFVDYELERTLKGWIPRRLGGGLGGKKESG---QLRFGGRDRPFR 163
Query: 219 YDERPGPSPLPHRDRDRDRERERRERSRERDKERE-RRRSRSRDRRRRSRSRDKEERRRS 277
+P P+ D R+ +RERRERSR R++ + R R R DR R R +++E R
Sbjct: 164 ---KPINLPVVKNDLYREGKRERRERSRSRERHWDSRTRDRDHDRGREKRWQEREPTRVW 220
Query: 278 RERSKDKDRDRKRRSSRSRERARRER 303
+ D +R+R R R + R ++ER
Sbjct: 221 PD--NDWERERDFRDDRIKGREKKER 244
Score = 32.7 bits (73), Expect = 0.67
Identities = 22/43 (51%), Positives = 24/43 (55%), Gaps = 4/43 (9%)
Query: 348 RDRDRERRRSHRSERERR---RDRDRDRDRDREHKRGERGSER 387
R+ RERR RS RER R RDRD DR RE + ER R
Sbjct: 177 REGKRERRERSRS-RERHWDSRTRDRDHDRGREKRWQEREPTR 218
Score = 32.0 bits (71), Expect = 1.1
Identities = 17/59 (28%), Positives = 30/59 (50%)
Query: 333 GELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDE 391
G+L G D P K + + +R + RR+R R R+R + + +R +RGR++
Sbjct: 151 GQLRFGGRDRPFRKPINLPVVKNDLYREGKRERRERSRSRERHWDSRTRDRDHDRGREK 209
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 355 RRSHRSERERRRDRDR---DRDRDREHKRGERGSERGRDEAR 393
R R RER R R+R R RDR+H RG + R+ R
Sbjct: 177 REGKRERRERSRSRERHWDSRTRDRDHDRGREKRWQEREPTR 218
Score = 30.4 bits (67), Expect = 3.3
Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
Query: 344 EEKGRDRDRERRRSHR-SERERRR---DRDRDRDRDREHKR--GERGSERGR 389
+ + RDRD +R R R ERE R D D +R+RD R G ERG+
Sbjct: 195 DSRTRDRDHDRGREKRWQEREPTRVWPDNDWERERDFRDDRIKGREKKERGK 246
>gi|31077198 small nuclear ribonucleoprotein 35kDa (U11/U12) isoform
b [Homo sapiens]
Length = 251
Score = 151 bits (382), Expect = 1e-36
Identities = 90/206 (43%), Positives = 120/206 (58%), Gaps = 9/206 (4%)
Query: 99 GDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMH 158
GD TLFVAR+N T E KL+ F YG I+R+ +V +G +GYAFIEY+ ER +
Sbjct: 52 GDPLLTLFVARLNLQTKEDKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEERAVI 111
Query: 159 SAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSR 218
AY+ ADG ID + VD E RT+KGW PRRLGGGLGG + G +R GRD R
Sbjct: 112 KAYRDADGLVIDQHEIFVDYELERTLKGWIPRRLGGGLGGKKESG---QLRFGGRDRPFR 168
Query: 219 YDERPGPSPLPHRDRDRDRERERRERSRERDKERE-RRRSRSRDRRRRSRSRDKEERRRS 277
+P P+ D R+ +RERRERSR R++ + R R R DR R R +++E R
Sbjct: 169 ---KPINLPVVKNDLYREGKRERRERSRSRERHWDSRTRDRDHDRGREKRWQEREPTRVW 225
Query: 278 RERSKDKDRDRKRRSSRSRERARRER 303
+ D +R+R R R + R ++ER
Sbjct: 226 PD--NDWERERDFRDDRIKGREKKER 249
Score = 32.7 bits (73), Expect = 0.67
Identities = 22/43 (51%), Positives = 24/43 (55%), Gaps = 4/43 (9%)
Query: 348 RDRDRERRRSHRSERERR---RDRDRDRDRDREHKRGERGSER 387
R+ RERR RS RER R RDRD DR RE + ER R
Sbjct: 182 REGKRERRERSRS-RERHWDSRTRDRDHDRGREKRWQEREPTR 223
Score = 32.0 bits (71), Expect = 1.1
Identities = 17/59 (28%), Positives = 30/59 (50%)
Query: 333 GELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDE 391
G+L G D P K + + +R + RR+R R R+R + + +R +RGR++
Sbjct: 156 GQLRFGGRDRPFRKPINLPVVKNDLYREGKRERRERSRSRERHWDSRTRDRDHDRGREK 214
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 355 RRSHRSERERRRDRDR---DRDRDREHKRGERGSERGRDEAR 393
R R RER R R+R R RDR+H RG + R+ R
Sbjct: 182 REGKRERRERSRSRERHWDSRTRDRDHDRGREKRWQEREPTR 223
Score = 30.4 bits (67), Expect = 3.3
Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
Query: 344 EEKGRDRDRERRRSHR-SERERRR---DRDRDRDRDREHKR--GERGSERGR 389
+ + RDRD +R R R ERE R D D +R+RD R G ERG+
Sbjct: 200 DSRTRDRDHDRGREKRWQEREPTRVWPDNDWERERDFRDDRIKGREKKERGK 251
>gi|31077200 small nuclear ribonucleoprotein 35kDa (U11/U12) isoform
b [Homo sapiens]
Length = 251
Score = 151 bits (382), Expect = 1e-36
Identities = 90/206 (43%), Positives = 120/206 (58%), Gaps = 9/206 (4%)
Query: 99 GDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMH 158
GD TLFVAR+N T E KL+ F YG I+R+ +V +G +GYAFIEY+ ER +
Sbjct: 52 GDPLLTLFVARLNLQTKEDKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEERAVI 111
Query: 159 SAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSR 218
AY+ ADG ID + VD E RT+KGW PRRLGGGLGG + G +R GRD R
Sbjct: 112 KAYRDADGLVIDQHEIFVDYELERTLKGWIPRRLGGGLGGKKESG---QLRFGGRDRPFR 168
Query: 219 YDERPGPSPLPHRDRDRDRERERRERSRERDKERE-RRRSRSRDRRRRSRSRDKEERRRS 277
+P P+ D R+ +RERRERSR R++ + R R R DR R R +++E R
Sbjct: 169 ---KPINLPVVKNDLYREGKRERRERSRSRERHWDSRTRDRDHDRGREKRWQEREPTRVW 225
Query: 278 RERSKDKDRDRKRRSSRSRERARRER 303
+ D +R+R R R + R ++ER
Sbjct: 226 PD--NDWERERDFRDDRIKGREKKER 249
Score = 32.7 bits (73), Expect = 0.67
Identities = 22/43 (51%), Positives = 24/43 (55%), Gaps = 4/43 (9%)
Query: 348 RDRDRERRRSHRSERERR---RDRDRDRDRDREHKRGERGSER 387
R+ RERR RS RER R RDRD DR RE + ER R
Sbjct: 182 REGKRERRERSRS-RERHWDSRTRDRDHDRGREKRWQEREPTR 223
Score = 32.0 bits (71), Expect = 1.1
Identities = 17/59 (28%), Positives = 30/59 (50%)
Query: 333 GELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDE 391
G+L G D P K + + +R + RR+R R R+R + + +R +RGR++
Sbjct: 156 GQLRFGGRDRPFRKPINLPVVKNDLYREGKRERRERSRSRERHWDSRTRDRDHDRGREK 214
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 355 RRSHRSERERRRDRDR---DRDRDREHKRGERGSERGRDEAR 393
R R RER R R+R R RDR+H RG + R+ R
Sbjct: 182 REGKRERRERSRSRERHWDSRTRDRDHDRGREKRWQEREPTR 223
Score = 30.4 bits (67), Expect = 3.3
Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
Query: 344 EEKGRDRDRERRRSHR-SERERRR---DRDRDRDRDREHKR--GERGSERGR 389
+ + RDRD +R R R ERE R D D +R+RD R G ERG+
Sbjct: 200 DSRTRDRDHDRGREKRWQEREPTRVWPDNDWERERDFRDDRIKGREKKERGK 251
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 117 bits (293), Expect = 2e-26
Identities = 100/375 (26%), Positives = 168/375 (44%), Gaps = 42/375 (11%)
Query: 46 REFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETEL-------KMWDPHNDPNAQ 98
R E RD +T ER ++ +E+ ++++E ETE + D + Q
Sbjct: 93 RHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQ 152
Query: 99 GDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMH 158
DA K E + + + E +R +R + E + E++
Sbjct: 153 RDAEK------------ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 159 SAYKHAD-GKKIDGRRVL-VDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDT 216
+ +H++ G++ + R + ER R R R+ R + +T
Sbjct: 201 TEDRHSERGRERERERETETETERKRQTDRERDRQRKT----EREREKQAERERASERET 256
Query: 217 SRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRD-RRRRSRSRDKE--- 272
R ER RDRDRDR+R ++ER R+ D++R+RR R R+ R+R R R++E
Sbjct: 257 ERDKERER-----ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
Query: 273 --ERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDG 330
R+R RER ++++R+R+R + R RE+ RER+RK + + G +
Sbjct: 312 ERNRKRERERERERERERQRETERDREK-ERERKRKRQTEMDRERNRQTGREGRRQAERE 370
Query: 331 PPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKR-----GERGS 385
E D E + R+RDR+R R ER+ +DRD R+ +++ +R ERG
Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430
Query: 386 ERGRDEARGGGGGQD 400
ERGR+ + G +D
Sbjct: 431 ERGREREKQKGRERD 445
Score = 110 bits (275), Expect = 3e-24
Identities = 112/391 (28%), Positives = 163/391 (41%), Gaps = 74/391 (18%)
Query: 52 RDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVN 111
+DA R R++ ER+R E+RQ E ET+ K + + D + R
Sbjct: 47 KDADGDDRERNRQKERERRR----EKRQTERETDRK-----RERRREKDRHR----KRDR 93
Query: 112 YDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDG 171
+ + +E E +R +R+ + E E ER + DG++
Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD---RQTDGQRERE 150
Query: 172 RRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRD---DTSRYDERPGPSPL 228
R+ + ER R R R+ T R R R + R E+ +
Sbjct: 151 RQRDAEKERERQTDRERQRQ-------TERNRQKEREREKNRQERRERERQREKENKTED 203
Query: 229 PHRDRDRDRERERR-----------------------------------ERSRERDKERE 253
H +R R+RERER ER ERDKERE
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Query: 254 RRRSRSRDRRRRSRSRDKE-ERRRSRERSKDKDRDRKRRSSRSRERAR-----RERER-- 305
R R R RDR RR + R+++ +R+R R +D++ +RKR R RER R RERER
Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER 323
Query: 306 ---KEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSER 362
+E R D + E + G +G + R+R+RER R +S R
Sbjct: 324 ERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAR 383
Query: 363 ERRRDRDRDRDRDREHKRGERGSERGRDEAR 393
E R +R+RDRDRDR+ +R ER +E+ RD R
Sbjct: 384 E-REERERDRDRDRQKER-ERQTEKDRDGQR 412
Score = 107 bits (268), Expect = 2e-23
Identities = 65/204 (31%), Positives = 102/204 (50%), Gaps = 17/204 (8%)
Query: 190 RRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERD 249
RR G RR G + + DD R +R ++R+R RE+R+ RE D
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRER-----------NRQKERERRREKRQTERETD 76
Query: 250 KERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEEL 309
++RERRR + R R+R + +R + RER D++RDR+R R+R++ RERE + E
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQK-ERERETEREG 135
Query: 310 RGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRD 369
G + + D E D E+ R +R R++ E+ R+ R+
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTD-----RERQRQTERNRQKEREREKNRQERRE 190
Query: 370 RDRDRDREHKRGERGSERGRDEAR 393
R+R R++E+K +R SERGR+ R
Sbjct: 191 RERQREKENKTEDRHSERGRERER 214
Score = 79.0 bits (193), Expect = 8e-15
Identities = 93/364 (25%), Positives = 144/364 (39%), Gaps = 23/364 (6%)
Query: 46 REFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTL 105
R E R+ ET ER + RE+ +R+ E E E K + + + K
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTERERE-KQAERERASERETERDKER 262
Query: 106 FVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHAD 165
R + D + ++E E KR R + + E E ER+ + +
Sbjct: 263 ERER-DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER 321
Query: 166 GKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGP 225
++ + R + ER R + R R+ + R GR R ER
Sbjct: 322 ERERERERQR-ETERDREKERERKRKRQTEMDRERNRQTG----REGRRQAERERERER- 375
Query: 226 SPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKD 285
RDR RERE RER R+RD+++ER R +DR + + + ER + RE + ++
Sbjct: 376 ----ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRE 431
Query: 286 RDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEE 345
R R+R + RE R+RER+ + R G + + PP G + D P+ P
Sbjct: 432 RGREREKQKGRE---RDRERQTD-RQAGRQRKRSTLYVNPPPRTARSGVVQSD-PNRPTR 486
Query: 346 KGRDRDRERRRSHRSE-----RERRRDRDRDRDRDR-EHKRGERGSERGRDEARGGGGGQ 399
R + S R + R R R R E + GE+ + G GG G
Sbjct: 487 GIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSGGFGT 546
Query: 400 DNGL 403
+N L
Sbjct: 547 ENPL 550
Score = 70.9 bits (172), Expect = 2e-12
Identities = 50/170 (29%), Positives = 71/170 (41%), Gaps = 36/170 (21%)
Query: 249 DKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEE 308
D R R S+ RRR K+ RER++ K+R+R+R ++ R+RER+ E
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
Query: 309 LRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDR 368
+ RDR RER+R ERER+ DR
Sbjct: 85 K---------------------------------DRHRKRDRHRERQRDREKERERQTDR 111
Query: 369 DRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESE 418
+RDR R++E R + ER R+ R G G+D +G R E E
Sbjct: 112 ERDRQREKERNRQK---ERERETEREGERGRDRQTDGQRERERQRDAEKE 158
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 113 bits (283), Expect = 3e-25
Identities = 65/166 (39%), Positives = 94/166 (56%), Gaps = 36/166 (21%)
Query: 231 RDRDRDRERERRERSRERDKERERRRSRSRDR-RRRSRSRDK-EERRRSRERSKDKDRDR 288
R+R+R+RERERRER RER++ERER + + R+R R R R RD+ +ER R R+R +D+DRDR
Sbjct: 312 RERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDR 371
Query: 289 KRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKG 347
+R S R+++R+R RE+ R E E+
Sbjct: 372 ERSSDRNKDRSRSREKSRDRERE---------------------------------RERE 398
Query: 348 RDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEAR 393
R+R+RER R ERER R+R+R+R+R+++ KR E E R
Sbjct: 399 REREREREREREREREREREREREREREKDKKRDREEDEEDAYERR 444
Score = 94.4 bits (233), Expect = 2e-19
Identities = 60/193 (31%), Positives = 99/193 (51%), Gaps = 12/193 (6%)
Query: 213 RDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKE 272
++D + + L R+ + R+ ++ + KE+ER+ ++RR R R R++E
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEI-EKERRERERERERE 319
Query: 273 ERRRSRERSKDKDRDRKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGP 331
RR RER ++++R+R++ R RER R R+R+R +E + D D
Sbjct: 320 RERREREREREREREREKEKERERERERDRDRDRTKERD------RDRDRERDRDRDRER 373
Query: 332 PGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDE 391
+ D EK RDR+RER R ERER R+R+R+R+R+RE ER ER +D+
Sbjct: 374 SSDRNKD-RSRSREKSRDRERERERERERERERERERERERERERER---EREREREKDK 429
Query: 392 ARGGGGGQDNGLE 404
R +++ E
Sbjct: 430 KRDREEDEEDAYE 442
Score = 92.0 bits (227), Expect = 9e-19
Identities = 63/166 (37%), Positives = 94/166 (56%), Gaps = 21/166 (12%)
Query: 231 RDRDRDRERER-RERSRERDKERERRRSRSRDR-RRRSRSRDK-EERRRSRERSKDKDRD 287
R+++++RERER R+R R+R KER+R R R RDR R R RS D+ ++R RSRE+S+D++R+
Sbjct: 335 REKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERE 394
Query: 288 RKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEK 346
R+R R RER R RERER+ E E + D D+ E E K
Sbjct: 395 REREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK-----LERK 449
Query: 347 GRDRD------------RERRRSHRSERERRRDRDRDRDRDREHKR 380
R+++ RER+++ E+E R+ +R R+ +E KR
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495
Score = 77.0 bits (188), Expect = 3e-14
Identities = 78/262 (29%), Positives = 119/262 (45%), Gaps = 34/262 (12%)
Query: 150 EYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIR 209
E E ER+ + ++ + R D +R RT + R R R +D N
Sbjct: 324 EREREREREREREKEKERERERER---DRDRDRTKERDRDRDRERDRDRDRERSSDRNKD 380
Query: 210 HSGRDDTSRYDERPGPSPLPHRDRDRDRERER-RERSRERDKERERRRSRSRDR------ 262
S + SR ER R+R+R+RERER RER RER++ERER + + RDR
Sbjct: 381 RSRSREKSRDRERERERER-EREREREREREREREREREREREREREKDKKRDREEDEED 439
Query: 263 ---RRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEP 319
RR+ + +E+ +ER K+ + ++++ + A RE ER+ E+ + E
Sbjct: 440 AYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEF 499
Query: 320 SEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRD-----RDR-- 372
E D DD P G + R RDRE + ER+R+R+++ R R
Sbjct: 500 LEDYDDDRDD-------PKYYRGSALQKRLRDRE-KEMEADERDRKREKEELEEIRQRLL 551
Query: 373 -----DRDREHKRGERGSERGR 389
D D E +R E+ +ER R
Sbjct: 552 AEGHPDPDAELQRMEQEAERRR 573
Score = 60.5 bits (145), Expect = 3e-09
Identities = 80/348 (22%), Positives = 133/348 (38%), Gaps = 72/348 (20%)
Query: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163
T+FV ++ ++ +R+ G + V SGK + + F EY+ A +
Sbjct: 88 TVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGA-SGKLQAFGFCEYKEPESTLRALRL 146
Query: 164 ADGKKIDGRRVLV--DVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDE 221
+I +++LV D + + W+ ++ G R + + ++T R D+
Sbjct: 147 LHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASN-GNARPETVTNDDEEALDEETKRRDQ 205
Query: 222 R-PGPSPLPHRDRDRDRERERRER-SRERDKERERRRSRSRD------------RRRRSR 267
G + R+ + +E S R K++E++ R +
Sbjct: 206 MIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDIN 265
Query: 268 SRDKEERRR---SRERSKDKDRDRK---RRSSRSRERARRERERKEELRGGGGDMAEPSE 321
+ + EE +R SRE SK +D +K + + +ER E+ER+E
Sbjct: 266 AIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRER------------- 312
Query: 322 AGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERR-----------RSHRSERERRRDRDR 370
E+ R+R+RERR R ERER R+RDR
Sbjct: 313 -----------------------ERERERERERREREREREREREREKEKERERERERDR 349
Query: 371 DRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESE 418
DRDR +E R +R ER RD R ++ SRD E E
Sbjct: 350 DRDRTKERDR-DRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 396
Score = 47.4 bits (111), Expect = 3e-05
Identities = 76/339 (22%), Positives = 122/339 (35%), Gaps = 37/339 (10%)
Query: 46 REFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTL 105
RE E R+ E ER + R++ + R ++ + E D D D K
Sbjct: 325 REREREREREREKEKERERERERDRDRDRTKERDRDRDRER---DRDRDRERSSDRNKDR 381
Query: 106 FVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHA- 164
+R E + RE E +R +R + E + +RD + A
Sbjct: 382 SRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAY 441
Query: 165 DGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRY----- 219
+ +K++ + + +K W R + + R + R
Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501
Query: 220 ---DERPGP-----SPLPHRDRDRDRERERRERSRERDKER-ERRRSRSRDR------RR 264
D+R P S L R RDR++E E ER R+R+KE E R R
Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAE 561
Query: 265 RSRSRDKEERRR----SRERSKDKDRDRKRRSSRSRERARRERERKEE-------LRGGG 313
R + ERRR +E +++ + K+ RE E E E+ LR
Sbjct: 562 LQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPIS 621
Query: 314 GDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDR 352
+ S +G+A P+ PG+ P G P E D+ +
Sbjct: 622 SAPSVSSASGNATPN--TPGDESPCGIIIPHENSPDQQQ 658
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 108 bits (271), Expect = 7e-24
Identities = 74/207 (35%), Positives = 99/207 (47%), Gaps = 51/207 (24%)
Query: 208 IRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRR--- 264
IRH GR+D DER + D RD R+R RERD+ERER R R RDR R
Sbjct: 645 IRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKE 704
Query: 265 ------RSRSRDKE-ERRRSRERSKDKDRDRKRRSSRSRERAR-RERERKEELRGGGGDM 316
R+R R++E E+ R RER +D+D DR+R R R+R + RERER+E R
Sbjct: 705 RELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERER------ 758
Query: 317 AEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDR-----DRD 371
+ E+ R+R+RER R ER++ R+R D+D
Sbjct: 759 ------------------------ERERERERERERERERERARERDKERERQRDWEDKD 794
Query: 372 RDRD-----REHKRGERGSERGRDEAR 393
+ RD RE R +R G DE +
Sbjct: 795 KGRDDRREKREEIREDRNPRDGHDERK 821
Score = 108 bits (270), Expect = 1e-23
Identities = 71/190 (37%), Positives = 104/190 (54%), Gaps = 18/190 (9%)
Query: 209 RHSGRD--DTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRS 266
RH RD D D+RP SP+ H+ R+ + ER+ R R D+ +RR R+R+R R
Sbjct: 625 RHGERDRRDNRERDQRPS-SPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRE- 682
Query: 267 RSRDKE-ERRRSRERSKDKDRDRKRRSSRSRERAR-RERER-KEELRGGGGDMAEPSEAG 323
R RD+E ER R RER ++++++R+ R+RER R RE+ER +E R D E
Sbjct: 683 RERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERER- 741
Query: 324 DAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGER 383
E + E + R+R+RER R ERER R+R R+RD++RE +R
Sbjct: 742 ----------ERDREKEREREREERERERERERERERERERERERARERDKERERQRDWE 791
Query: 384 GSERGRDEAR 393
++GRD+ R
Sbjct: 792 DKDKGRDDRR 801
Score = 73.2 bits (178), Expect = 4e-13
Identities = 51/165 (30%), Positives = 77/165 (46%), Gaps = 10/165 (6%)
Query: 231 RDRDRDRERERRERSRERDKERERRRSRSRDRRR---RSRSRDKEERRRSRERSKDKDRD 287
RDR+++RERER ER RER++ERER R R R+R R R + R+++ +++ +D R+
Sbjct: 743 RDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRRE 802
Query: 288 RKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKG 347
++ R ERK + R P ++ + P + G D EK
Sbjct: 803 KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSG-DDKNEKH 861
Query: 348 R-----DRDRERRRSHRSE-RERRRDRDRDRDRDREHKRGERGSE 386
R R +E R S E R+ R ++ DR E K R E
Sbjct: 862 RLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYE 906
Score = 65.5 bits (158), Expect = 9e-11
Identities = 63/198 (31%), Positives = 83/198 (41%), Gaps = 26/198 (13%)
Query: 226 SPLPHRDRDRDRERERRER-SRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDK 284
SP HR R++ R ER S+ D+ ERR R R SR++ E + + S+D
Sbjct: 387 SPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDH 446
Query: 285 DRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPD-----DGPPGELGPDG 339
DR+ R R R AR R+R+ ELR DM + E D D D D
Sbjct: 447 RDDREPRDGRDRRDARDTRDRR-ELR-DSRDMRDSREMRDYSRDTKESRDPRDSRSTRDA 504
Query: 340 PDGPEEKGRDRDR------ERRRSH-----RSERERRRDRDRDRDRDREHKRGER-GSER 387
D + +GRD R E RS+ R E R R+ R+ R R +R G R
Sbjct: 505 HDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSR 564
Query: 388 GR------DEARGGGGGQ 399
GR +RG G Q
Sbjct: 565 GRVPELPEKGSRGSRGSQ 582
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/216 (26%), Positives = 89/216 (41%), Gaps = 30/216 (13%)
Query: 210 HSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSR 269
HS R + D + RDR +ER+R E RER++ER R R DR
Sbjct: 1273 HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWP 1332
Query: 270 DKEERRRSRERSKDKDRDRKRRSSRSRER-----ARRERERKEELRGGGGDMAEPSEAGD 324
+R R RER ++++RD++R R RER R+R+R + R E + +
Sbjct: 1333 RNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRD-RTFESSQIESVKRCE 1391
Query: 325 APPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRD-------RDRDRDRE 377
A + E RD + R S ++E R D+D + ++
Sbjct: 1392 AKLEG---------------EHERDLESTSRDSLALDKE-RMDKDLGSVQGFEETNKSER 1435
Query: 378 HKRGERGSERGR-DEARGGGGGQDNGLEGLGNDSRD 412
+ E G + + D+A G G G E + +D D
Sbjct: 1436 TESLEAGDDESKLDDAHSLGSGAGEGYEPISDDELD 1471
Score = 60.8 bits (146), Expect = 2e-09
Identities = 78/297 (26%), Positives = 122/297 (41%), Gaps = 46/297 (15%)
Query: 156 DMHSAYKHADGKKIDGRRVLV-DVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRD 214
D H +K++ V + D + + + R LG + R +R D
Sbjct: 1155 DSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNR--SNRSHTSGRLRSPSND 1212
Query: 215 DTSRY-DERPGPSPLPHR-DRDRDRER------ERRERSRE-------RDKERERRRSRS 259
R D++ G + H RDR++ + ER+ R + R +R+ SRS
Sbjct: 1213 SAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRS 1272
Query: 260 RDRRRRSRSRDKEERRRSRE-RSKDKDRDRKR-RSSRSRERARRERERKEELRGGGGDMA 317
RR S D++ RS S+D+ ++R R R RER RR+ ++E R D
Sbjct: 1273 HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWP 1332
Query: 318 EPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERER----RRDRDRDRD 373
+ D E+ R+R+R++RR ERER +RDRDRD
Sbjct: 1333 RNRDR------------------DRLRERERERERDKRRDLDRERERLISDSVERDRDRD 1374
Query: 374 RDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESEGGDGYLAPENGY 430
RDR + + S + R EA+ G + LE DS + ++ E D L G+
Sbjct: 1375 RDRTFESSQIESVK-RCEAK-LEGEHERDLESTSRDS--LALDKERMDKDLGSVQGF 1427
Score = 50.4 bits (119), Expect = 3e-06
Identities = 48/192 (25%), Positives = 78/192 (40%), Gaps = 11/192 (5%)
Query: 231 RDRDRDRERERRERSRERDKERERR---RSRSRDRRRRSRSRDKEERRRSRERSKDKDRD 287
+DR ++ R+ ++R R+ +++RE+R RS S + S + S+ S +
Sbjct: 287 KDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHS 346
Query: 288 ----RKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGP 343
RKR S S +R R+ ++ P P P E G +
Sbjct: 347 PSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERT 406
Query: 344 EEKGRDRDRERRRSHRSERERRRD--RDRDRDRDREHKRGERGSERGRDEARGGGGGQDN 401
+ DR ERR R +R+R +D +R+ ++D+ R R RD R +D
Sbjct: 407 SQ-SHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRD-GRDRRDARDT 464
Query: 402 GLEGLGNDSRDM 413
DSRDM
Sbjct: 465 RDRRELRDSRDM 476
Score = 47.0 bits (110), Expect = 3e-05
Identities = 77/383 (20%), Positives = 136/383 (35%), Gaps = 36/383 (9%)
Query: 49 EDPRDAPPPTRAETREERMERKRREKIER-RQQEVETELKMWDPHNDPNAQGDAFKTLFV 107
+D RD R RE ER+R + ER R++E E EL+ + + + + +
Sbjct: 669 DDRRDERARERDRERERDRERERERERERDREREKERELER-ERAREREREREKERDRER 727
Query: 108 ARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGK 167
R E + RE + +R + + R E E ER+ K
Sbjct: 728 DRDRDHDRERERERERDREKEREREREERERERERER-----ERERERERERERARERDK 782
Query: 168 KIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSP 227
+ + +R D ++GR + + + R + H R RY PSP
Sbjct: 783 ERERQRDWEDKDKGRDDRREKREEI--------REDRNPRDGHDERKSKKRYRNEGSPSP 834
Query: 228 LPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKE---ERRRSRERSKDK 284
R R+ + + DK + R R + SRS E R+ R + +D+
Sbjct: 835 RQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDR 894
Query: 285 DRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPE 344
+RK S R E+ +E+ + + ++ E S +
Sbjct: 895 KPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRM------------------RAQD 936
Query: 345 EKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLE 404
G + +R S R+ E ++ + ++ K + G ERG E G + +
Sbjct: 937 IIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKK 996
Query: 405 GLGNDSRDMYMESEGGDGYLAPE 427
G S + + GD ++ E
Sbjct: 997 GQKKKSIEKKRKKSKGDSDISDE 1019
Score = 44.3 bits (103), Expect = 2e-04
Identities = 81/388 (20%), Positives = 139/388 (35%), Gaps = 56/388 (14%)
Query: 53 DAPPPTRAETREERMERKRREKIER-RQQEVETELKMWDPHNDPNAQGDAFKTLFVARVN 111
++ P R E+ R K KI + R E E E W+ + D + GD +N
Sbjct: 107 ESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGD---------IN 157
Query: 112 YDTTES---KLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKK 168
YD +++R+ I+R M + + + R I+ E ++ + K
Sbjct: 158 YDYVHELSLEMKRQ-----KIQRELMKLEQENMEKREEIIIKKEVSPEVVRS-------K 205
Query: 169 IDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGP-SP 227
+ L + K P+ + + R+ + ++ GP +P
Sbjct: 206 LSPSPSLRKSSKSPKRKS-SPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTP 264
Query: 228 LPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERS------ 281
P D ++ + + + K+R ++R R R R +E+R + R S
Sbjct: 265 SPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHH 324
Query: 282 ---KDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPD-----DGPPG 333
+ +S S +R RK P A P P
Sbjct: 325 SPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQR 384
Query: 334 ELGPDGPDGP-EEKGR-DRDR-----ERRRSHRSERERRRDRDRDRDRDREHKRGERGSE 386
+ P P EKGR D +R +RR R + +RDR++D +RE+++ + S
Sbjct: 385 KQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSR 444
Query: 387 RGRD--EARGGGGGQDNGLEGLGNDSRD 412
RD E R G +D D+RD
Sbjct: 445 DHRDDREPRDGRDRRD------ARDTRD 466
Score = 39.7 bits (91), Expect = 0.005
Identities = 73/344 (21%), Positives = 128/344 (37%), Gaps = 62/344 (18%)
Query: 46 REFEDPRDAPPPTRAETREERMERKRREKIER-RQQEVETELKM-WDP----HNDPNAQG 99
RE E R+ R RE ER+R + ER R+++ E E + W+ +D +
Sbjct: 745 REKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKR 804
Query: 100 DAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHS 159
+ + R +D +SK R E S PR EH D
Sbjct: 805 EEIREDRNPRDGHDERKSKKRYRNE--------------GSPSPRQSPKRRREHSPDS-D 849
Query: 160 AYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRY 219
AY D K + R+L V R + + P L
Sbjct: 850 AYNSGDDKN-EKHRLLSQVVRPQESRSLSPSHLT-------------------------- 882
Query: 220 DERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRE 279
++R G R ++ DR+ ER+E SR +++ + + S D++R E SR
Sbjct: 883 EDRQG------RWKEEDRKPERKESSRRYEEQELKEKVSSVDKQR----EQTEILESSRM 932
Query: 280 RSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDG 339
R++D + + +RA E ++K +++ + + D + G DG
Sbjct: 933 RAQDIIGHHQSEDRETSDRAHDENKKKAKIQ---KKPIKKKKEDDVGIERGNIETTSEDG 989
Query: 340 PDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGER 383
+KG+ + ++ +S+ + D + + + KRG R
Sbjct: 990 QVFSPKKGQKKKSIEKKRKKSKGDSDIS-DEEAAQQSKKKRGPR 1032
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 104 bits (260), Expect = 1e-22
Identities = 65/170 (38%), Positives = 93/170 (54%), Gaps = 37/170 (21%)
Query: 230 HRDRDRDRERER---RERSRERDKERERRRSRSRD-----RRRRSRSRDKEERRRS-RER 280
HR RDR RER+R RE+ RER KER+R+R R R+ R+R R R +E +R++ RER
Sbjct: 37 HRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRER 96
Query: 281 SKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGP 340
KD+DR+RKR + R+RER R+ GG + + +E
Sbjct: 97 DKDRDRERKRETDRNRERNRK----------GGRERDKQTER------------------ 128
Query: 341 DGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRD 390
+ E+ R R RER R + ER+R DR+R R +RE ++ ER ER ++
Sbjct: 129 ERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
Score = 99.4 bits (246), Expect = 6e-21
Identities = 61/183 (33%), Positives = 88/183 (48%), Gaps = 33/183 (18%)
Query: 215 DTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEER 274
+ R ER + +R R RDR RER R+ D+E+ER R + RDR+R+ + E
Sbjct: 20 ERDRQRERENQTERENRHRQRDRHRER---DRQTDREKERERQKERDRQRQRERETERET 76
Query: 275 RRSRERSKDKDR----DRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDG 330
R RER + ++R DR+R R RER R +E R GG + + +E
Sbjct: 77 ERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTE--------- 127
Query: 331 PPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRD 390
R+RDRER R + ERER+R R+R R+ DRE +R ER ++
Sbjct: 128 -----------------RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKE 170
Query: 391 EAR 393
+
Sbjct: 171 RKK 173
Score = 85.5 bits (210), Expect = 9e-17
Identities = 57/189 (30%), Positives = 91/189 (48%), Gaps = 51/189 (26%)
Query: 231 RDRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRK 289
R R+R RE +R +E RERD++RER R+ R R R +R R R+R D++++R+
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQR-----DRHRERDRQTDREKERE 57
Query: 290 RRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRD 349
R+ R R+R +RER+ E
Sbjct: 58 RQKERDRQR---QRERETE----------------------------------------- 73
Query: 350 RDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGND 409
R+ ER+R + +RER+R DR+RD+DR+ +R +R ++R R+ R GG +D E +
Sbjct: 74 RETERQRERQRQRERKRQTDRERDKDRDRER-KRETDRNRERNRKGGRERDKQTERERDR 132
Query: 410 SRDMYMESE 418
R+ + E
Sbjct: 133 ERERQRQRE 141
Score = 79.0 bits (193), Expect = 8e-15
Identities = 51/166 (30%), Positives = 79/166 (47%), Gaps = 46/166 (27%)
Query: 231 RDRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRK 289
R R+R R+RER R+ RERDK+R+R R R DR R + ER + ER +D++R+R+
Sbjct: 78 RQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQ 137
Query: 290 RRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRD 349
R+ R R+ R+RERK R+
Sbjct: 138 RQRERERQ---RQRERK-----------------------------------------RE 153
Query: 350 RDRERRR-SHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARG 394
DRER+R + R ER++ R ++R ++R + K +R ++ R G
Sbjct: 154 TDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199
Score = 47.4 bits (111), Expect = 3e-05
Identities = 60/232 (25%), Positives = 93/232 (40%), Gaps = 53/232 (22%)
Query: 59 RAETREERMERKRREKIERRQQ-EVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTES 117
R R + ER+R + ER Q E E + D H + + Q D K R +
Sbjct: 9 RETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKE----RERQKERDR 64
Query: 118 KLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVD 177
+ +RE E +R + ER K ++ D R D
Sbjct: 65 QRQRERETERETER--------------------QRERQRQRERKRQTDRERDKDR---D 101
Query: 178 VERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDR 237
ER R R R R+GG + + + D R +R R+R+R R
Sbjct: 102 RERKRETDRNRERN--------RKGGRERDKQTERERDRERERQR-------QRERERQR 146
Query: 238 ERER-----RERSR--ERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSK 282
+RER RER R ER+ ER++ R ++R++ + + KEE+RR ++ K
Sbjct: 147 QRERKRETDRERQRWAERE---ERKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 41.6 bits (96), Expect = 0.001
Identities = 19/46 (41%), Positives = 28/46 (60%)
Query: 345 EKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRD 390
E+ R+R RE R +ERER R R+R+ +RE++ +R R RD
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERD 47
Score = 37.7 bits (86), Expect = 0.021
Identities = 20/68 (29%), Positives = 31/68 (45%)
Query: 351 DRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDS 410
+R+R R ++R + +R+RDR R+RE++ R RD R D E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 411 RDMYMESE 418
RD + E
Sbjct: 62 RDRQRQRE 69
Score = 37.4 bits (85), Expect = 0.027
Identities = 17/45 (37%), Positives = 26/45 (57%)
Query: 349 DRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEAR 393
+R RER+R +E R+RDR R+R+ + +R R +R R R
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRER 46
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 103 bits (258), Expect = 2e-22
Identities = 79/328 (24%), Positives = 151/328 (46%), Gaps = 52/328 (15%)
Query: 94 DPNAQGDAFKTLFVARVNYDTTES-KLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYE 152
DP+ + +T++V +N TT + +L F+ G +K + M + +P +AF+E+
Sbjct: 173 DPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDET--QPTRFAFVEFA 230
Query: 153 HERDMHSAYKHADGKKIDGRRVLVDVERGRTVKG--WRPRRLG----------------- 193
+ + A +G R + ++ VK P+
Sbjct: 231 DQNSVPRALAF-NGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFI 289
Query: 194 -------GGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSR 246
G R+GG + S +S+ R S HR R +R R R ++ R
Sbjct: 290 SAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSR-QKDR 348
Query: 247 ERDKERERRRSRSRDRRR-RSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERER 305
R K ++RS+SR+RR+ RSRS +++R+ +RE+ K+K+R +++ R +ER R +
Sbjct: 349 RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEK--DREKEREREKERE 406
Query: 306 KEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERR 365
KE+ RG D + E D ++K +DR+RER + H +R++
Sbjct: 407 KEKERGKNKDRDKERE------------------KDREKDKEKDREREREKEHEKDRDKE 448
Query: 366 RDRDRDRDRDREHKRGERGSERGRDEAR 393
+++++D++++RE R + E+ + + +
Sbjct: 449 KEKEQDKEKEREKDRSKEIDEKRKKDKK 476
Score = 75.5 bits (184), Expect = 9e-14
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 31/203 (15%)
Query: 230 HRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRK 289
++DRD++RE++ RE+ +E+D+ERER + +DR + +E+ R ++RSK+ D RK
Sbjct: 414 NKDRDKEREKD-REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 472
Query: 290 R--------------RSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGEL 335
+ R SRS R RR R + R ++ + P
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS------PSPR 526
Query: 336 GPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRD----------RDREHKRGERGS 385
+ D EK RD ERR RS R+ DRD +++EH + S
Sbjct: 527 SRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSS 586
Query: 386 ERGRDEARGGGGGQDNGLEGLGN 408
+ + ++N ++ GN
Sbjct: 587 VSKEVDDKDAPRTEENKIQHNGN 609
Score = 49.3 bits (116), Expect = 7e-06
Identities = 53/244 (21%), Positives = 93/244 (38%), Gaps = 63/244 (25%)
Query: 154 ERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGR 213
ER + H+ K+ D R + + ER + + R + G ++ R
Sbjct: 363 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERG-----KNKDR 417
Query: 214 DDTSRYDERPGPSPLPHRDRDRDRERER-RERSRERDKERERRRSRSRD----------- 261
D D R+R+++ E++R +E+ +E+DKE+ER + RS++
Sbjct: 418 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKS 477
Query: 262 --------------------RRRRSRSRDKEER-----------------RRSRERSKDK 284
RRRRSRS + R R +++ ++K
Sbjct: 478 RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 537
Query: 285 DRD-----RKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDG 339
+RD R+R S S ++ +R+ KE+L + E + PD E+ D
Sbjct: 538 ERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH--NKEPDSSVSKEV--DD 593
Query: 340 PDGP 343
D P
Sbjct: 594 KDAP 597
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 103 bits (258), Expect = 2e-22
Identities = 79/328 (24%), Positives = 151/328 (46%), Gaps = 52/328 (15%)
Query: 94 DPNAQGDAFKTLFVARVNYDTTES-KLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYE 152
DP+ + +T++V +N TT + +L F+ G +K + M + +P +AF+E+
Sbjct: 57 DPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDET--QPTRFAFVEFA 114
Query: 153 HERDMHSAYKHADGKKIDGRRVLVDVERGRTVKG--WRPRRLG----------------- 193
+ + A +G R + ++ VK P+
Sbjct: 115 DQNSVPRALAF-NGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFI 173
Query: 194 -------GGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSR 246
G R+GG + S +S+ R S HR R +R R R ++ R
Sbjct: 174 SAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSR-QKDR 232
Query: 247 ERDKERERRRSRSRDRRR-RSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERER 305
R K ++RS+SR+RR+ RSRS +++R+ +RE+ K+K+R +++ R +ER R +
Sbjct: 233 RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEK--DREKEREREKERE 290
Query: 306 KEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERR 365
KE+ RG D + E D ++K +DR+RER + H +R++
Sbjct: 291 KEKERGKNKDRDKERE------------------KDREKDKEKDREREREKEHEKDRDKE 332
Query: 366 RDRDRDRDRDREHKRGERGSERGRDEAR 393
+++++D++++RE R + E+ + + +
Sbjct: 333 KEKEQDKEKEREKDRSKEIDEKRKKDKK 360
Score = 75.5 bits (184), Expect = 9e-14
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 31/203 (15%)
Query: 230 HRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRK 289
++DRD++RE++ RE+ +E+D+ERER + +DR + +E+ R ++RSK+ D RK
Sbjct: 298 NKDRDKEREKD-REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 356
Query: 290 R--------------RSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGEL 335
+ R SRS R RR R + R ++ + P
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS------PSPR 410
Query: 336 GPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRD----------RDREHKRGERGS 385
+ D EK RD ERR RS R+ DRD +++EH + S
Sbjct: 411 SRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSS 470
Query: 386 ERGRDEARGGGGGQDNGLEGLGN 408
+ + ++N ++ GN
Sbjct: 471 VSKEVDDKDAPRTEENKIQHNGN 493
Score = 49.3 bits (116), Expect = 7e-06
Identities = 53/244 (21%), Positives = 93/244 (38%), Gaps = 63/244 (25%)
Query: 154 ERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGR 213
ER + H+ K+ D R + + ER + + R + G ++ R
Sbjct: 247 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERG-----KNKDR 301
Query: 214 DDTSRYDERPGPSPLPHRDRDRDRERER-RERSRERDKERERRRSRSRD----------- 261
D D R+R+++ E++R +E+ +E+DKE+ER + RS++
Sbjct: 302 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKS 361
Query: 262 --------------------RRRRSRSRDKEER-----------------RRSRERSKDK 284
RRRRSRS + R R +++ ++K
Sbjct: 362 RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 421
Query: 285 DRD-----RKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDG 339
+RD R+R S S ++ +R+ KE+L + E + PD E+ D
Sbjct: 422 ERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH--NKEPDSSVSKEV--DD 477
Query: 340 PDGP 343
D P
Sbjct: 478 KDAP 481
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 101 bits (252), Expect = 1e-21
Identities = 76/233 (32%), Positives = 103/233 (44%), Gaps = 30/233 (12%)
Query: 176 VDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDR 235
+D RGR PR G G G DD R +R RDRDR
Sbjct: 47 LDFSRGRLGSQESPRSWGLGQAHKDADG----------DDRQRERDRVREKTEKERDRDR 96
Query: 236 DRERERRERSRE--------------RDKERERRRSRSRDRRR-RSRSRDKEERRRSRER 280
R+RERR + +E RD+ERE+++ R R+R R R R RD++ R + RER
Sbjct: 97 KRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRD-REKERER 155
Query: 281 SKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGP 340
+KDRD +R + RER R ++KE D +E D
Sbjct: 156 QTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKT-- 213
Query: 341 DGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEAR 393
E+ R+ DRE R RER+RDRDR ++RDRE R E + + E +
Sbjct: 214 --QTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERK 264
Score = 90.1 bits (222), Expect = 4e-18
Identities = 52/169 (30%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 231 RDRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRK 289
R+RDRDRE+ER R+ ++RD +RE R RDR R + + ER R R+R +K+R+R+
Sbjct: 143 RERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQ 202
Query: 290 RRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRD 349
R R+R + ++E R G + D E+ RD
Sbjct: 203 TDRERDRQRKTQTERQRETDREGERE------------------------TDRRRERQRD 238
Query: 350 RDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGG 398
RDR + R +R+ R ++R ++R +E K ++ +R D+ R G G
Sbjct: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287
Score = 75.9 bits (185), Expect = 7e-14
Identities = 62/236 (26%), Positives = 104/236 (44%), Gaps = 49/236 (20%)
Query: 152 EHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHS 211
+ +RD K + + R ++ER R + + R G R D
Sbjct: 95 DRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERE 154
Query: 212 GRDDTSRYDERPGPSPLPHRDRDRDRERERR-ERSRER----DKERERRRSRSRDRRRRS 266
+ + R +R + RDR+R++++ER ER R+R +KERER+ R RDR+R++
Sbjct: 155 RQTEKDRDGQRETETER-ERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKT 213
Query: 267 RSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAP 326
++ + E R ER D+ R+R+R R +ER RER+RKEE
Sbjct: 214 QTERQRETDREGERETDRRRERQRDRDRGKER-DRERDRKEE------------------ 254
Query: 327 PDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGE 382
+K R ++R++ R + + E+RR+ D++ K GE
Sbjct: 255 -----------------RKKERKKERKKERKEKKKEEKRRE-------DKKRKWGE 286
Score = 66.2 bits (160), Expect = 5e-11
Identities = 72/264 (27%), Positives = 112/264 (42%), Gaps = 61/264 (23%)
Query: 59 RAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESK 118
R +T +ER +R R+ ERR++E ET N D K + R +
Sbjct: 85 REKTEKER-DRDRKRDRERRRKEKET-----------NRNRDREKQTEIERDREREKQKG 132
Query: 119 LRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVL-VD 177
RE + RG E E +RD + K DG+R +
Sbjct: 133 RERE-------------------RDRGR---ERERDRDREKERERQTEKDRDGQRETETE 170
Query: 178 VERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDR 237
ER R + + R T R + DT + ER DR+RDR
Sbjct: 171 RERDREREKQKERE-------TERD-------RDRQRDTEKERER-------QTDRERDR 209
Query: 238 ERERR-ERSRERDKERERRRSRSRDRRRRSRSRDK-EERRRSRERSKDKDRDRKRRSSRS 295
+R+ + ER RE D+E ER R RR R R RD+ +ER R R+R +++ ++RK+ +
Sbjct: 210 QRKTQTERQRETDREGERETDR---RRERQRDRDRGKERDRERDRKEERKKERKKERKKE 266
Query: 296 RERARRERERKEELRGGGGDMAEP 319
R+ ++E +R+E+ + G+ P
Sbjct: 267 RKEKKKEEKRREDKKRKWGEGISP 290
Score = 42.7 bits (99), Expect = 6e-04
Identities = 29/85 (34%), Positives = 48/85 (56%), Gaps = 5/85 (5%)
Query: 338 DGPDGPEEKGRDRDR---ERRRSHRSERERRR-DRDRDRDRDREHKRGERGSERGRDEAR 393
DG D E+ R R++ ER R + +RERRR +++ +R+RDRE K+ E +R R++ +
Sbjct: 73 DGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDRE-KQTEIERDREREKQK 131
Query: 394 GGGGGQDNGLEGLGNDSRDMYMESE 418
G +D G E + R+ E +
Sbjct: 132 GRERERDRGRERERDRDREKERERQ 156
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 101 bits (251), Expect = 2e-21
Identities = 78/220 (35%), Positives = 109/220 (49%), Gaps = 30/220 (13%)
Query: 209 RHSGRDDTSRYDERPGP-SPLPHRDRDRDRERERRER-SRERDKER----------ERRR 256
R S R SR R G S R+ +R++ER+R ER ++ER+KER ERRR
Sbjct: 270 RRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRR 329
Query: 257 SRSRDRRR-RSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERAR---------RERERK 306
SRSR+R R RSRSRD++ RR R+R ++K+ +R RR R ++ R R RER
Sbjct: 330 SRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERS 389
Query: 307 EELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRR 366
+E R G++ E D DD + D D +EK R R R R HRS R
Sbjct: 390 KEQR-SRGEVEEKKHKED--KDDRRHRD---DKRDSKKEKKHSRSRSRERKHRSRSRSRN 443
Query: 367 --DRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLE 404
R R R +++ K E+ +R G G+ + +E
Sbjct: 444 AGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVE 483
Score = 84.0 bits (206), Expect = 3e-16
Identities = 65/220 (29%), Positives = 99/220 (45%), Gaps = 31/220 (14%)
Query: 188 RPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERER------ 241
R R + GL R + RH R SR +R G RDRDR+RE+E
Sbjct: 317 RSRSIDRGLERRRSRSRE---RHRSR---SRSRDRKGD----RRDRDREREKENERGRRR 366
Query: 242 -----RERSRERDKERERRRSRSRDRRRRSRSRDKEER-----RRSRERSKDKDRDRKRR 291
+ER ER+KERER R RS+++R R +K+ + RR R+ +D +++K
Sbjct: 367 DRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHS 426
Query: 292 SSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRD 351
SRSRER R R R R G S+ + + + G + + +
Sbjct: 427 RSRSRERKHRSRSRS---RNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVE 483
Query: 352 RERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDE 391
+ ++R H +E+ R R R ++R HKR S+ D+
Sbjct: 484 KSKKREHSPSKEK--SRKRSRSKERSHKRDHSDSKDQSDK 521
Score = 72.8 bits (177), Expect = 6e-13
Identities = 58/182 (31%), Positives = 83/182 (45%), Gaps = 26/182 (14%)
Query: 230 HRDRDRDRERERRERSRERDKERERRRSR--------------SRDRRRRSRSRDKEERR 275
H +R R R RR S R R R RS R++ R+ R+ +ER
Sbjct: 254 HVERRRSRS-PRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKERE 312
Query: 276 RSRERSKDKDRDRKRRSSRSRERAR---RERERKEELRGGGGDMAEPSEAGDAPPDDGPP 332
+ R RS+ DR +RR SRSRER R R R+RK + R + + +E G D
Sbjct: 313 KERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRD--- 369
Query: 333 GELGPDGPDGPE-EKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDE 391
D G E EK R+R RER + RS E + ++ DR H+ +R S++ +
Sbjct: 370 ----YDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKH 425
Query: 392 AR 393
+R
Sbjct: 426 SR 427
Score = 69.3 bits (168), Expect = 6e-12
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 34/159 (21%)
Query: 230 HRDRDRDRERERRERSRERDKERERR-RSRSRDRRRRSRSRDKEERRRSRERSKDKDRDR 288
HRD RD ++E++ SR R +ER+ R RSRSR+ +RSRSR KE+ + + SK+K R
Sbjct: 412 HRDDKRDSKKEKKH-SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR 470
Query: 289 KRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGR 348
R S+ R + + +++E PS +EK R
Sbjct: 471 SRSGSQGRTDSVEKSKKREH---------SPS-----------------------KEKSR 498
Query: 349 DRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSER 387
R R + RSH+ + +D+ DR R + E+
Sbjct: 499 KRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEK 537
Score = 63.9 bits (154), Expect = 3e-10
Identities = 62/201 (30%), Positives = 85/201 (42%), Gaps = 34/201 (16%)
Query: 227 PLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRS-RDKEERRRSRERSKDKD 285
P+P + ++ D++ + R R ++D + RRRSRS R RRS RS+ +
Sbjct: 222 PVPVQ-KNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRS 280
Query: 286 RDRK--------RRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGP 337
R+ R R +ER R ERE KE E D G
Sbjct: 281 HHREGHGSSSFDRELEREKERQRLEREAKER---------EKERRRSRSIDRG------- 324
Query: 338 DGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGG 397
E+ R R RER RS R+R+ DR RDRDR+RE K ERG R RD + G
Sbjct: 325 ------LERRRSRSRERHRSRSRSRDRKGDR-RDRDRERE-KENERGRRRDRDYDKERGN 376
Query: 398 GQDNGLEGLGNDSRDMYMESE 418
++ E S++ E
Sbjct: 377 EREKERERSRERSKEQRSRGE 397
Score = 48.1 bits (113), Expect = 2e-05
Identities = 64/283 (22%), Positives = 117/283 (41%), Gaps = 28/283 (9%)
Query: 33 HHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPH 92
HH + + G + + RE E ++ R E +E ER+R I+R + + + + H
Sbjct: 281 HHREGH-GSSSFDRELEREKERQRLER-EAKEREKERRRSRSIDRGLERRRSRSR--ERH 336
Query: 93 NDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYE 152
+ D D + RE E +R Y K G R E E
Sbjct: 337 RSRSRSRDR---------KGDRRDRDREREKENERGRRR-DRDYDKERGNER-----EKE 381
Query: 153 HERDMHSAYKHADGKKIDGRRVLVDVE--RGRTVK--GWRPRRLGGGLGGTRRGGADVNI 208
ER + + +++ ++ D + R R K + ++ R+ +
Sbjct: 382 RERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRS 441
Query: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRER---ERRERSRERDKERERRRSRSRDRRRR 265
R++G+ SR E+ +++ R R + R S E+ K+RE S+ + R+R
Sbjct: 442 RNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKS-RKR 500
Query: 266 SRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEE 308
SRS+++ +R SKD+ RR S+S E+ +E++ K +
Sbjct: 501 SRSKER-SHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNK 542
Score = 34.7 bits (78), Expect = 0.18
Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 5/73 (6%)
Query: 212 GRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDK 271
GR D+ ++ SP + R R R +ER S +RD + +S D RRRS+S ++
Sbjct: 477 GRTDSVEKSKKREHSPSKEKSRKRSRSKER---SHKRDHSDSKDQSDKHD-RRRSQSIEQ 532
Query: 272 EERRRSRERSKDK 284
E + + + ++KD+
Sbjct: 533 ESQEK-QHKNKDE 544
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 100 bits (250), Expect = 2e-21
Identities = 75/231 (32%), Positives = 113/231 (48%), Gaps = 29/231 (12%)
Query: 168 KIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSP 227
K +GR + E T+ R RR R + RHS RD
Sbjct: 4 KTEGRHTHTETE---TMDRQRERRRETDRERDRAKESKTEDRHSERDR------------ 48
Query: 228 LPHRDRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDR 286
RDR+R+RER+R RER ++ D+E ER+R R RDR R+ + + ++ R +R + DR
Sbjct: 49 --QRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDR 106
Query: 287 DRKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEE 345
+R+++ R ER R RERE+++E+ G + D + E E+
Sbjct: 107 ERQKQKEREMERVRDREREKQKEM----GRERQTDRETDRERERQAERERETGRERKTED 162
Query: 346 KGRDRDRERRRSHR-----SERERRRDRDRDRDRDREHKRG-ERGSERGRD 390
+ R+R+RER+R ERER D +R+R R+ + KR +R SER RD
Sbjct: 163 RHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 95.9 bits (237), Expect = 6e-20
Identities = 62/179 (34%), Positives = 93/179 (51%), Gaps = 17/179 (9%)
Query: 231 RDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKR 290
R+RDR +E + +R ERD++R+R R+R RDR R + E R RER +D+DR R+
Sbjct: 29 RERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRET 88
Query: 291 RSSRSRER-------ARRERERKEEL---RGGGGDMAEPSEAG-----DAPPDDGPPGEL 335
R +ER RER++++E R + + E G D D +
Sbjct: 89 ERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQA 148
Query: 336 GPDGPDGPEEKGRDRDRERRRSHRSERERRRD-RDRDRDRDREHKRGERGSERGRDEAR 393
+ G E K DR RER R + ERER+R+ ++R+R D E +R +R ++R RD R
Sbjct: 149 ERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERER-QRETDRKRDRQR 206
Score = 75.1 bits (183), Expect = 1e-13
Identities = 53/168 (31%), Positives = 86/168 (51%), Gaps = 41/168 (24%)
Query: 231 RDRDRDRERERRERSRERDKERERRRSRSRDRRR-RSRSRDKE-ERRRSRERSKDKDRDR 288
R+ DR+R+R + ++ +R ER+R+R R R+R R R R R+K+ +R R+R +++DRDR
Sbjct: 25 RETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDR 84
Query: 289 KRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGR 348
+R + R R++ RE +R E D +K +
Sbjct: 85 QRETERERDK-ERETDRHTET-------------------------------DRERQKQK 112
Query: 349 DRDRERRRSHRSERERRRDRD--RDRDRDREHKR-GERGSERGRDEAR 393
+R+ ER R +RER + ++ R+R DRE R ER +ER R+ R
Sbjct: 113 EREMERVR----DREREKQKEMGRERQTDRETDRERERQAERERETGR 156
Score = 57.8 bits (138), Expect = 2e-08
Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 6/127 (4%)
Query: 268 SRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPP 327
S+ + + + D+ R+R+R + R R+RA +E K E R D E +
Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRA---KESKTEDRHSERDRQRDRER-NRER 58
Query: 328 DDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDRE-HKRGERGSE 386
D E D +G ++ R+RDR+R+R ER++ R+ DR + DRE K+ ER E
Sbjct: 59 DRDREREKQTD-REGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREME 117
Query: 387 RGRDEAR 393
R RD R
Sbjct: 118 RVRDRER 124
Score = 40.0 bits (92), Expect = 0.004
Identities = 24/59 (40%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 346 KGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLE 404
+GR E R +RERRR+ DR+RDR +E K +R SER R R +D E
Sbjct: 6 EGRHTHTETETMDR-QRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
Score = 29.3 bits (64), Expect = 7.4
Identities = 17/67 (25%), Positives = 26/67 (38%)
Query: 353 ERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRD 412
E R +H R R+R R+ DRE R + R R ++ E + R+
Sbjct: 6 EGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
Query: 413 MYMESEG 419
+ EG
Sbjct: 66 KQTDREG 72
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 97.8 bits (242), Expect = 2e-20
Identities = 75/226 (33%), Positives = 108/226 (47%), Gaps = 30/226 (13%)
Query: 95 PNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHE 154
P+ +G +L V + Y T+ LRR FE YG + +++ + + + RG+AF+ + +
Sbjct: 8 PDVEG--MTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDK 65
Query: 155 RDMHSAYKHADGKKIDGRRVLVDVER-GR------TVKGWRPRRLGGGLGGTRRGGADVN 207
RD A DG +DGR + V + R GR + +G PRR GGG G R
Sbjct: 66 RDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRR------- 118
Query: 208 IRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDR-RRRS 266
SR R S R R R R R R RS+ R + R R RS S+ R RRS
Sbjct: 119 ---------SRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRS 169
Query: 267 RSRDKE-ERRRSRERSKDKDRDR---KRRSSRSRERARRERERKEE 308
+S+ R RSR RS+ + R +R S+SR R++ + EE
Sbjct: 170 KSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEE 215
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 96.3 bits (238), Expect = 5e-20
Identities = 66/197 (33%), Positives = 99/197 (50%), Gaps = 29/197 (14%)
Query: 229 PHRD---RDRDRERERRERSRERDKE-RERRRSRSRDRRRRSRSRDKEERRRSRERSKDK 284
P RD + +ERE RE+ RER++E RER+R R + R + R+RD+E R+RSR RS+
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 285 DRDRKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGP 343
R RR SRSR+ R R RER+ R D D
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERR---RSRSRDRRRSR------------------SHDRS 339
Query: 344 EEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGG--GGGQDN 401
E K R R R+RRRS +R+ + R + RDR+++ K E+ +RG D+ + G ++
Sbjct: 340 ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK-EKRGSDDKKSSVKSGSREK 398
Query: 402 GLEGLGNDSRDMYMESE 418
E +S++ ++E
Sbjct: 399 QSEDTNTESKESDTKNE 415
Score = 76.3 bits (186), Expect = 5e-14
Identities = 53/139 (38%), Positives = 73/139 (52%), Gaps = 25/139 (17%)
Query: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSR--------------------ER 248
R R+ ER R+++R R+RERR+RSR +R
Sbjct: 257 REKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKR 316
Query: 249 DKERERRRSRSRDRRRRSRSRDKEERR---RSRERSKDKDRDRKRRSSRSRERAR-RERE 304
+ RERRRSRSRD RRRSRS D+ ER+ RSR+R + K RDRK RS+ R R ++R+
Sbjct: 317 SRSRERRRSRSRD-RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK 375
Query: 305 RKEELRGGGGDMAEPSEAG 323
KE+ + G D ++G
Sbjct: 376 SKEKEKRGSDDKKSSVKSG 394
Score = 71.6 bits (174), Expect = 1e-12
Identities = 53/183 (28%), Positives = 79/183 (43%), Gaps = 24/183 (13%)
Query: 242 RERSRERDK-ERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERAR 300
R+R+ E D+ ER ++ + R+ R + R R++EER R R R +++ R R+R+R R
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEE-----REKERARDRER 289
Query: 301 RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSH-- 358
R+R R S + D + R RDR R RSH
Sbjct: 290 RKRSRSRSRHSSRTSDRRCSRSRD-----------HKRSRSRERRRSRSRDRRRSRSHDR 338
Query: 359 --RSERERRRDRDRDRDRDR---EHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDM 413
R R R RDR R + RDR +H+ R E+ R G D+ + + SR+
Sbjct: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
Query: 414 YME 416
E
Sbjct: 399 QSE 401
Score = 65.1 bits (157), Expect = 1e-10
Identities = 48/136 (35%), Positives = 65/136 (47%), Gaps = 20/136 (14%)
Query: 200 RRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRS 259
RR + RHS R R R+R R R R+RR RSR D+ + RSRS
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR-RSRSHDRSERKHRSRS 347
Query: 260 RDRRR-----------RSRSRDKEERRRSRERSKDKDRDRKRR-SSRSRER-------AR 300
RDRRR RS+SRD+E+ R+S+E+ K D+K S SRE+
Sbjct: 348 RDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTES 407
Query: 301 RERERKEELRGGGGDM 316
+E + K E+ G D+
Sbjct: 408 KESDTKNEVNGTSEDI 423
Score = 37.7 bits (86), Expect = 0.021
Identities = 24/106 (22%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERER-------RERSRERDKERERRRSRSRD 261
R R R S HR R RDR R + + RS+ RD+E++R+ S+ ++
Sbjct: 322 RRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK-SKEKE 380
Query: 262 RRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKE 307
+R + + ++S+D + + K +++ E + E
Sbjct: 381 KRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 96.3 bits (238), Expect = 5e-20
Identities = 66/197 (33%), Positives = 99/197 (50%), Gaps = 29/197 (14%)
Query: 229 PHRD---RDRDRERERRERSRERDKE-RERRRSRSRDRRRRSRSRDKEERRRSRERSKDK 284
P RD + +ERE RE+ RER++E RER+R R + R + R+RD+E R+RSR RS+
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 285 DRDRKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGP 343
R RR SRSR+ R R RER+ R D D
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERR---RSRSRDRRRSR------------------SHDRS 339
Query: 344 EEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGG--GGGQDN 401
E K R R R+RRRS +R+ + R + RDR+++ K E+ +RG D+ + G ++
Sbjct: 340 ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK-EKRGSDDKKSSVKSGSREK 398
Query: 402 GLEGLGNDSRDMYMESE 418
E +S++ ++E
Sbjct: 399 QSEDTNTESKESDTKNE 415
Score = 76.3 bits (186), Expect = 5e-14
Identities = 53/139 (38%), Positives = 73/139 (52%), Gaps = 25/139 (17%)
Query: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSR--------------------ER 248
R R+ ER R+++R R+RERR+RSR +R
Sbjct: 257 REKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKR 316
Query: 249 DKERERRRSRSRDRRRRSRSRDKEERR---RSRERSKDKDRDRKRRSSRSRERAR-RERE 304
+ RERRRSRSRD RRRSRS D+ ER+ RSR+R + K RDRK RS+ R R ++R+
Sbjct: 317 SRSRERRRSRSRD-RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK 375
Query: 305 RKEELRGGGGDMAEPSEAG 323
KE+ + G D ++G
Sbjct: 376 SKEKEKRGSDDKKSSVKSG 394
Score = 71.6 bits (174), Expect = 1e-12
Identities = 53/183 (28%), Positives = 79/183 (43%), Gaps = 24/183 (13%)
Query: 242 RERSRERDK-ERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERAR 300
R+R+ E D+ ER ++ + R+ R + R R++EER R R R +++ R R+R+R R
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEE-----REKERARDRER 289
Query: 301 RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSH-- 358
R+R R S + D + R RDR R RSH
Sbjct: 290 RKRSRSRSRHSSRTSDRRCSRSRD-----------HKRSRSRERRRSRSRDRRRSRSHDR 338
Query: 359 --RSERERRRDRDRDRDRDR---EHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDM 413
R R R RDR R + RDR +H+ R E+ R G D+ + + SR+
Sbjct: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
Query: 414 YME 416
E
Sbjct: 399 QSE 401
Score = 65.1 bits (157), Expect = 1e-10
Identities = 48/136 (35%), Positives = 65/136 (47%), Gaps = 20/136 (14%)
Query: 200 RRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRS 259
RR + RHS R R R+R R R R+RR RSR D+ + RSRS
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR-RSRSHDRSERKHRSRS 347
Query: 260 RDRRR-----------RSRSRDKEERRRSRERSKDKDRDRKRR-SSRSRER-------AR 300
RDRRR RS+SRD+E+ R+S+E+ K D+K S SRE+
Sbjct: 348 RDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTES 407
Query: 301 RERERKEELRGGGGDM 316
+E + K E+ G D+
Sbjct: 408 KESDTKNEVNGTSEDI 423
Score = 37.7 bits (86), Expect = 0.021
Identities = 24/106 (22%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERER-------RERSRERDKERERRRSRSRD 261
R R R S HR R RDR R + + RS+ RD+E++R+ S+ ++
Sbjct: 322 RRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK-SKEKE 380
Query: 262 RRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKE 307
+R + + ++S+D + + K +++ E + E
Sbjct: 381 KRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 95.5 bits (236), Expect = 8e-20
Identities = 57/166 (34%), Positives = 91/166 (54%), Gaps = 12/166 (7%)
Query: 232 DRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKR 290
++DRDR+R+R RER R RD++R+R R RDR + +++ ER+R R+R KD++R R+R
Sbjct: 85 EKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQR 144
Query: 291 RSSRSRER---ARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKG 347
++R ++R+R+ E M E D + E D + +
Sbjct: 145 EIGIDKDREIETEKDRDRERE-------MGETERYRDRERERQKQRETRRDRDRERQREK 197
Query: 348 RDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEAR 393
DR+R+R R E++R R+R+ RDRD+E R ER E+ RD +
Sbjct: 198 EDRERDRDRQKEREKDRYRERETGRDRDKERDR-ERQREKDRDRQK 242
Score = 95.1 bits (235), Expect = 1e-19
Identities = 66/186 (35%), Positives = 104/186 (55%), Gaps = 18/186 (9%)
Query: 226 SPLPHRDRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERR---RSRERS 281
+P R+R+R RERER R+R++ER +E++R + RDR+R+ RD+E +R R R+R
Sbjct: 53 APAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRK---RDRERQRWRDRDRKRE 109
Query: 282 KDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAG-DAPPDDGPPGELGPDGP 340
+ DRDR+ + R ER R+ ++E+ R + E G D + + +
Sbjct: 110 RWGDRDRETETERQEERERQRDRKREKDR----ERQRQREIGIDKDREIETEKDRDRERE 165
Query: 341 DGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERG--SERGRDEARGGGGG 398
G E+ RDR+RER++ +RE RRDRDR+R R++E + +R ER +D R G
Sbjct: 166 MGETERYRDRERERQK----QRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETG 221
Query: 399 QDNGLE 404
+D E
Sbjct: 222 RDRDKE 227
Score = 92.8 bits (229), Expect = 5e-19
Identities = 68/189 (35%), Positives = 104/189 (55%), Gaps = 28/189 (14%)
Query: 222 RPGPSPLPHRDRDRDRERERR---ERSRERDKERERRRSRSRDR-RRRSRSRDKEERR-- 275
R P+ + R+R R+RER+R+ ER RE+D+E E+ R R R R R R R RD++ +R
Sbjct: 51 RVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRER 110
Query: 276 ---RSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPP 332
R RE ++ +R+R+ R RE+ R ER+R+ E+ G D E D
Sbjct: 111 WGDRDRETETERQEERERQRDRKREKDR-ERQRQREI---GIDKDREIET---EKDRDRE 163
Query: 333 GELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDR---DRDRDRDREHKR-----GERG 384
E+G + + R+R+R+++R R +R+R R R DR+RDRDR+ +R ER
Sbjct: 164 REMG----ETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERE 219
Query: 385 SERGRDEAR 393
+ R RD+ R
Sbjct: 220 TGRDRDKER 228
Score = 82.8 bits (203), Expect = 6e-16
Identities = 61/174 (35%), Positives = 89/174 (51%), Gaps = 37/174 (21%)
Query: 230 HRDRDR----DRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDK 284
HR++DR DR+R+R R+R R+R ++R+R+R R DR R + + +EER R R+R ++K
Sbjct: 77 HREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREK 136
Query: 285 DRDRKRR--------------SSRSRERA----------RRERERKEELRGGGGDMAEPS 320
DR+R+R+ R RER RER+++ E R D
Sbjct: 137 DRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDR-DRERQR 195
Query: 321 EAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDR 374
E D D E D E GRDRD+ER +RER+R++DRDR +
Sbjct: 196 EKEDRERDRDRQKEREKDRYR-ERETGRDRDKER------DRERQREKDRDRQK 242
Score = 73.9 bits (180), Expect = 3e-13
Identities = 45/154 (29%), Positives = 73/154 (47%), Gaps = 43/154 (27%)
Query: 231 RDRDRDRERER-RERSRERDKERERRRSRSRD---RRRRSRSRDKEERRRSRERSKDKDR 286
R +R+R+R+R RE+ RER ++RE + R+ + R R R+ E R R+R +++ +
Sbjct: 122 RQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQK 181
Query: 287 DRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEK 346
R+ R R RER R + +R E+
Sbjct: 182 QRETRRDRDRERQREKEDR---------------------------------------ER 202
Query: 347 GRDRDRERRRSHRSERERRRDRDRDRDRDREHKR 380
RDR +ER + ERE RDRD++RDR+R+ ++
Sbjct: 203 DRDRQKEREKDRYRERETGRDRDKERDRERQREK 236
Score = 66.6 bits (161), Expect = 4e-11
Identities = 37/87 (42%), Positives = 52/87 (59%), Gaps = 19/87 (21%)
Query: 232 DRDRDRERER------RERSRERDKERERRRSRSRDRRR----RSRSRDKE--------- 272
++DRDRERE R+R RER K+RE RR R R+R+R R R RD++
Sbjct: 157 EKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYR 216
Query: 273 ERRRSRERSKDKDRDRKRRSSRSRERA 299
ER R+R K++DR+R+R R R++A
Sbjct: 217 ERETGRDRDKERDRERQREKDRDRQKA 243
Score = 66.2 bits (160), Expect = 5e-11
Identities = 35/79 (44%), Positives = 51/79 (64%), Gaps = 7/79 (8%)
Query: 215 DTSRYDERPGPSPLPH---RDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDK 271
+T RY +R RDRDR+R+RE+ +R R+RD+++ER + R R+R R RDK
Sbjct: 168 ETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERET-GRDRDK 226
Query: 272 EERRRSRERSKDKDRDRKR 290
E R RER ++KDRDR++
Sbjct: 227 E---RDRERQREKDRDRQK 242
Score = 28.9 bits (63), Expect = 9.6
Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 13/83 (15%)
Query: 349 DRDRERRRSHRSERERRRDRDRDRDRDREHKRG-------------ERGSERGRDEARGG 395
DRD R R R+R+R R+R+R+ KR +R +R RD R
Sbjct: 41 DRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQR 100
Query: 396 GGGQDNGLEGLGNDSRDMYMESE 418
+D E G+ R+ E +
Sbjct: 101 WRDRDRKRERWGDRDRETETERQ 123
>gi|16905517 FUS interacting protein (serine-arginine rich) 1
isoform 2 [Homo sapiens]
Length = 262
Score = 92.0 bits (227), Expect = 9e-19
Identities = 81/276 (29%), Positives = 115/276 (41%), Gaps = 39/276 (14%)
Query: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163
+LFV V DT LRREF YGPI +++ + +PRG+A++++E RD A +
Sbjct: 11 SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
Query: 164 ADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGR-DDTSRYDER 222
D K I GR++ + +G P ++ G N+ S R DD RY
Sbjct: 71 LDRKWICGRQIEIQFAQGDRK---TPNQMKAKEGR--------NVYSSSRYDDYDRY--- 116
Query: 223 PGPSPLPHRDRDRDRERERRERSRERDKERER----RRSRSRDRRRRSRSRDKEERRRSR 278
R R R ER RR RSR D R R SR R RRSRS +R + R
Sbjct: 117 -------RRSRSRSYER-RRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHR 168
Query: 279 ERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPD 338
RS + + R SRS+ + ++E + K R + D+
Sbjct: 169 NRSFSRSKSNSR--SRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSK----------TH 216
Query: 339 GPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDR 374
G + R +E RS R + R R + R R
Sbjct: 217 YKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSR 252
Score = 36.2 bits (82), Expect = 0.060
Identities = 39/160 (24%), Positives = 52/160 (32%), Gaps = 42/160 (26%)
Query: 236 DRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRS 295
DR+ + +++E R DR RRSRSR E RRRSR RS D + R S
Sbjct: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYE-RRRSRSRSFDYNYRRSYSPRNS 147
Query: 296 RERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERR 355
R R R R D DR +
Sbjct: 148 RPTGRPRRSRSHS----------------------------------------DNDRFKH 167
Query: 356 RSHRSERERRRDRDRDRDR-DREHKRGERGSERGRDEARG 394
R+ R + R R + + +E K R + RG
Sbjct: 168 RNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRG 207
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 90.1 bits (222), Expect = 4e-18
Identities = 64/203 (31%), Positives = 100/203 (49%), Gaps = 43/203 (21%)
Query: 218 RYDERPGPSPLPHRDRDRDRERERRERSR-----ERDKERE--RRRSRSRDRRRRSRSRD 270
R ++R + + +R+RE ERRER+R +RDK RE R RSRSRDRRR+ R++
Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKS 1191
Query: 271 KEERRRSRERSKDK-------DRDRKRRSSR-------------SRERARRERERKEELR 310
KE++ +E+++++ D RK +++ +E R ER ++ E R
Sbjct: 1192 KEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKR 1251
Query: 311 GGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDR 370
+ E E + E+ R +RE+RR H ER+R R+R+R
Sbjct: 1252 RKEQEEEEQKEREK----------------EAERERNRQLEREKRREHSRERDRERERER 1295
Query: 371 DRDRDREHKRGERGSERGRDEAR 393
+RDR + ER ERGR+ R
Sbjct: 1296 ERDRGDRDRDRERDRERGRERDR 1318
Score = 84.0 bits (206), Expect = 3e-16
Identities = 63/194 (32%), Positives = 95/194 (48%), Gaps = 24/194 (12%)
Query: 223 PGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSK 282
P P P R RE+ER R + ++ERE R R R R R RDK R R RS+
Sbjct: 1122 PPPVQPPQHPRAEQREQERAVREQWAEREREMER-RERTRSEREWDRDKV-REGPRSRSR 1179
Query: 283 DKDRDRKRRS-SRSRERARRERERKEELRGGGGDMAEPSEAGDA----PPDD-------- 329
+DR RK R+ S+ ++ ++E+ ++E D+ ++A P D
Sbjct: 1180 SRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEA 1239
Query: 330 -----GPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERR----RDRDRDRDRDREHKR 380
E + E+K R+++ ER R+ + ERE+R R+RDR+R+R+RE R
Sbjct: 1240 ERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDR 1299
Query: 381 GERGSERGRDEARG 394
G+R +R RD RG
Sbjct: 1300 GDRDRDRERDRERG 1313
Score = 67.4 bits (163), Expect = 2e-11
Identities = 39/76 (51%), Positives = 48/76 (63%), Gaps = 8/76 (10%)
Query: 231 RDRDRDRERE-RRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRK 289
R+R+R ERE RRE SRERD+ERER R R R R R R RD RER +++DR
Sbjct: 1269 RERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERD-------RERGRERDRRDT 1321
Query: 290 RRSSRSRERARRERER 305
+R SRSR R+ R+R
Sbjct: 1322 KRHSRSRSRSTPVRDR 1337
Score = 66.2 bits (160), Expect = 5e-11
Identities = 40/112 (35%), Positives = 59/112 (52%), Gaps = 5/112 (4%)
Query: 205 DVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERE-RRERSRERDKERERRRSRSRDRR 263
D I + R ER + ++RE+E RER+R+ ++E+ R SR RDR
Sbjct: 1231 DSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRE 1290
Query: 264 R-RSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGG 314
R R R RD+ +R R RER +++ R+R RR ++ R R R R +R GG
Sbjct: 1291 RERERERDRGDRDRDRERDRERGRERDRRDTK---RHSRSRSRSTPVRDRGG 1339
Score = 37.4 bits (85), Expect = 0.027
Identities = 42/171 (24%), Positives = 75/171 (43%), Gaps = 22/171 (12%)
Query: 229 PHRDRDRDRERERRERSRER---DKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKD 285
P + R R+ S E+ D E+ R+ R R R++R+ E + E +D++
Sbjct: 194 PELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQE 253
Query: 286 ---RDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDG 342
R+ + R+ R+ + E E +EE + + E GD D+G P +
Sbjct: 254 TPSRNLRVRADRNLKTEEEEEEEEEE------EEDDEEEEGD---DEGQKSREAPILKEF 304
Query: 343 PEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEAR 393
EE G + R + ER + R ++++ +RG R + R ++EAR
Sbjct: 305 KEE-GEEIPRVKPEEMMDERPKTRSQEQE-----VLERGGRFT-RSQEEAR 348
Score = 37.4 bits (85), Expect = 0.027
Identities = 42/197 (21%), Positives = 75/197 (38%), Gaps = 27/197 (13%)
Query: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERS-----------RERDKERERRRS 257
RHS R +S +E+ R +R R R+ R+ E D+E R
Sbjct: 200 RHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNL 259
Query: 258 RSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMA 317
R R R ++EE E ++++ D + + SR + +E EE+
Sbjct: 260 RVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEI-----PRV 314
Query: 318 EPSEAGDAPPDDGPPGELGPDGPDGPEEKGR--DRDRERRRSHRSERERRRDRDRD---R 372
+P E D P + + E GR E R+SH + +++ ++
Sbjct: 315 KPEEMMDERP------KTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLE 368
Query: 373 DRDREHKRGERGSERGR 389
+ +RE K + E+ +
Sbjct: 369 EEEREIKSSQGLKEKSK 385
Score = 35.8 bits (81), Expect = 0.079
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 15/76 (19%)
Query: 331 PPGELGPDGPDGPEEKGRDRDR-------------ERRRSHRSERERRRDRDRDRDRDRE 377
PP + P P P + R+++R ERR RSERE RD+ R+ R R
Sbjct: 1121 PPPPVQP--PQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRS 1178
Query: 378 HKRGERGSERGRDEAR 393
R R ER + + +
Sbjct: 1179 RSRDRRRKERAKSKEK 1194
Score = 33.5 bits (75), Expect = 0.39
Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 7/111 (6%)
Query: 214 DDTSRYDERPGPSPLPHRDRDRDRERERRE---RSRERDKERERRRSRSRDRRRRSRSRD 270
D +S S R R D R RS++RD + R + R R +
Sbjct: 575 DSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRST 634
Query: 271 KEERRRSRERSKDKDRDRKRRSSR--SRERARRERERKEELRGGGGDMAEP 319
E R RSR RS+ + ++ S SR+ + E K+ G ++A P
Sbjct: 635 SESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDP--SSGQEVATP 683
>gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens]
Length = 322
Score = 89.7 bits (221), Expect = 5e-18
Identities = 77/302 (25%), Positives = 127/302 (42%), Gaps = 47/302 (15%)
Query: 105 LFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHA 164
+F+ + Y+ TE + F YG I I++V K++GK +G+ F+ YE +R A +
Sbjct: 38 IFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNF 97
Query: 165 DGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPG 224
+G KI GR + VD V +R + + DD +R + G
Sbjct: 98 NGIKIKGRTIRVD-----HVSNYRAPKDSEEI-----------------DDVTRQLQEKG 135
Query: 225 -----PSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRE 279
PSP + D + ++ + +++K+++++ DR ++ RR
Sbjct: 136 CGARTPSP-SLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTV 194
Query: 280 RSKDKDRDRKRRSSRSRERARRERERKEE-------LRGGGGDMAEPSEAGDAPPDDGPP 332
+ KD D K+ SS++ ERA++ R+ + GG + E + P +
Sbjct: 195 KEKD-DTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHE--- 250
Query: 333 GELGPDGPDGPEEKGRDRDRERRR-------SHRSERERRRDRDRDRDRDREHKRGERGS 385
+ EEK R RDR R + RSE R R R RD+ HKR R
Sbjct: 251 -HKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKSHRHKRARRSR 309
Query: 386 ER 387
ER
Sbjct: 310 ER 311
Score = 39.7 bits (91), Expect = 0.005
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Query: 212 GRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRS----RSRDRRRRSR 267
G +D R ++ P H+ R RE + R R+R + + S RS R RSR
Sbjct: 234 GAEDLERELKKEKPKH-EHKSSSRREAREEKTRIRDRGRSSDAHSSWYNGRSEGRSYRSR 292
Query: 268 SRDKEERRRSRERSKDKDRDRKRRSSRSR 296
SR +++ R + + ++R+ S R R
Sbjct: 293 SRSRDKSHRHKRARRSRERESSNPSDRWR 321
>gi|9558733 transformer-2 alpha [Homo sapiens]
Length = 282
Score = 88.6 bits (218), Expect = 1e-17
Identities = 70/219 (31%), Positives = 97/219 (44%), Gaps = 18/219 (8%)
Query: 58 TRAETREERMERKRREK-----IERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNY 112
TR+ + R+ R + RR+ + + H A D L V ++
Sbjct: 69 TRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSL 128
Query: 113 DTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGR 172
TTE LR F YGP+ +++VY +R+G+ RG+AF+ +E D A + A+G ++DGR
Sbjct: 129 YTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGR 188
Query: 173 RVLVD---VERGRT----VKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGP 225
R+ VD +R T + RP GGG GG GG GR S YD G
Sbjct: 189 RIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGG----GGGRRRDSYYDR--GY 242
Query: 226 SPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRR 264
R D D RR S + R R RSRS RR
Sbjct: 243 DRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRSYSPRR 281
Score = 46.6 bits (109), Expect = 4e-05
Identities = 68/237 (28%), Positives = 81/237 (34%), Gaps = 26/237 (10%)
Query: 212 GRDDTSRYDERPG-PSPLPHRDRDRDRERER-----RERSRERDKERERRRSRSRDRRRR 265
GR+ S+ G P+ + R R R SR R K R R R S R R
Sbjct: 11 GRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTR 70
Query: 266 SRSRDKEERRRSRERSKDKDRDRKR------RSSRSRERARRERERKEELRGGGGDMAEP 319
SRS RRRSR RS + R+R S+R R R G G
Sbjct: 71 SRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYT 130
Query: 320 SEAGDAPPDDGPPGELGPDGPDGPEEKGRDRD-----RERRRSHRSERERRRDRDRDRDR 374
+E D G L + GR R ER + ER + D R
Sbjct: 131 TER-DLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRR 189
Query: 375 DREH----KRGER---GSERGR-DEARGGGGGQDNGLEGLGNDSRDMYMESEGGDGY 423
R KR G GR + GGGGG G G G RD Y + GY
Sbjct: 190 IRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGRRRDSYYDRGYDRGY 246
Score = 32.3 bits (72), Expect = 0.87
Identities = 26/69 (37%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERE----RRERSRERDKERERRRSRSR---- 260
+HS SR R HR R R RR RSR E RRRSRS
Sbjct: 44 KHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMS 103
Query: 261 DRRRRSRSR 269
+RRR + SR
Sbjct: 104 NRRRHTGSR 112
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 87.8 bits (216), Expect = 2e-17
Identities = 52/189 (27%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 206 VNIRHSGRDDTSRYDERPGPS-PLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRR 264
V+ H + T R ER R R+R++ER+R +E+ K ++R R + R+R+R
Sbjct: 20 VSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR 79
Query: 265 RSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGD 324
+ R + ++ERR R + K++ ++ R R R ++++ERKE R +
Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK--- 136
Query: 325 APPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERG 384
+++ ++R RE+ R R ER+R++ + +R++ RE R ER
Sbjct: 137 ---------------KRRKKKRRKERKREKERGKR-ERKRKKRKKEEREKKRERNRKERK 180
Query: 385 SERGRDEAR 393
ER R E R
Sbjct: 181 KERERKERR 189
Score = 84.7 bits (208), Expect = 1e-16
Identities = 52/168 (30%), Positives = 91/168 (54%), Gaps = 5/168 (2%)
Query: 231 RDRDRDRERERRERSRERDKERER-RRSRSRDRRRRSRS-RDKEERRRSRERSKDKDRDR 288
R+R ++RER+R+ER ++R + RE+ RR R +++++R R R + ER++ +ER K+++R+
Sbjct: 69 RERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER-KEREREN 127
Query: 289 KRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKG- 347
K+R R R++ R+++ RKE R E + E E+
Sbjct: 128 KQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKE 187
Query: 348 -RDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARG 394
R+R +ER++ R ++ER++DR DR D + R R S R G
Sbjct: 188 RRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTG 235
Score = 78.2 bits (191), Expect = 1e-14
Identities = 48/170 (28%), Positives = 82/170 (48%), Gaps = 45/170 (26%)
Query: 227 PLPHRDRDRDRER-ERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKD 285
P R+ +R +ER ER +R RER+KER+R R + ++R+ R R KE R+ +ER K +
Sbjct: 28 PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR- 86
Query: 286 RDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEE 345
++R+ + R R++ +++RERK+
Sbjct: 87 KERREKERRKRKKEKKKRERKQ-------------------------------------- 108
Query: 346 KGRDRDRERRRSHRSERERRRDRDRDRDRDREHKR-GERGSERGRDEARG 394
R R R+ + +ER R+ + R+R R+ +R +R ER R++ RG
Sbjct: 109 ----RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG 154
Score = 66.6 bits (161), Expect = 4e-11
Identities = 38/106 (35%), Positives = 58/106 (54%), Gaps = 5/106 (4%)
Query: 221 ERPGPSPLPHRDRDRDRERERRERSRERDKER-ERRRSRSRDRRRRSRS-RDKEERRRSR 278
ER R+R+ + RER+ + R + K R ER+R + R +R R R R KEER + R
Sbjct: 113 ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172
Query: 279 ERSKD---KDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSE 321
ER++ K+R+RK R R +ER + R++KE + D S+
Sbjct: 173 ERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 60.8 bits (146), Expect = 2e-09
Identities = 26/86 (30%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Query: 213 RDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKE 272
R++ R + + R ++R RE+ER +R R+R K ++ R + R+R R+ R +++E
Sbjct: 125 RENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERE 184
Query: 273 ERRRSRERSKDKDRDRKRRSSRSRER 298
+ R RER K++ ++R+++ R ++R
Sbjct: 185 RKER-RERKKERKKERRKKKERKKDR 209
Score = 43.1 bits (100), Expect = 5e-04
Identities = 56/222 (25%), Positives = 87/222 (39%), Gaps = 33/222 (14%)
Query: 59 RAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESK 118
R + R ER +RKR + ER+++ + E K + K R E +
Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95
Query: 119 LRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDV 178
R++ + KR K RG ER K + + R
Sbjct: 96 KRKKEK------------KKRERKQRG------RRERKKKKERKERERENKQRR------ 131
Query: 179 ERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRE 238
ER R + + RR R+ + R R + +ER ++R ++RE
Sbjct: 132 ERKRKKRRKKKRRK------ERKREKERGKRERKRKKRKK-EEREKKRERNRKERKKERE 184
Query: 239 R-ERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRE 279
R ERRER +ER KER +++ R +D R+ R D + R RE
Sbjct: 185 RKERRERKKERKKERRKKKERKKD-RKTDRQTDSQVFRPLRE 225
Score = 38.1 bits (87), Expect = 0.016
Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 40/119 (33%)
Query: 279 ERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPD 338
+R ++ ++R+ R R RER E+ERK E
Sbjct: 31 QRESERKKERREREKRKRER---EKERKRER----------------------------- 58
Query: 339 GPDGPEEKGRDRDRERRRSHRSERER-RRDRDRDRDRDREHKRGERGSERGRDEARGGG 396
G +EK + + RER + ERER R++R++ R RE +R +R E+ + E + G
Sbjct: 59 ---GKKEKKKRKKRERGK----ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 85.9 bits (211), Expect = 7e-17
Identities = 73/247 (29%), Positives = 106/247 (42%), Gaps = 26/247 (10%)
Query: 181 GRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERP-------GPSPLPHRDR 233
GR + +R R G G+R + + S R D R R S R R
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 234 DRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSS 293
RDR+R RR RSRERD+ RERRRSRSRDRR RSR + RRSR S + S
Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRR---RSRSRSRGRRSRSSSPGNKSKKTENRS 118
Query: 294 RSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRE 353
RS+E+ GG+ ++ + +D + G + EE+ R R
Sbjct: 119 RSKEKT------------DGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKER 166
Query: 354 RRRSHRSERERRRDRDRDRDRD-REHKRGERGSERGRDEAR---GGGGGQDNGLEGLGND 409
+ +R++ + + ++ E K+G++ S D+ + N +EG D
Sbjct: 167 VEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELD 226
Query: 410 SRDMYME 416
D YME
Sbjct: 227 PLDAYME 233
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 83.2 bits (204), Expect = 4e-16
Identities = 58/168 (34%), Positives = 89/168 (52%), Gaps = 29/168 (17%)
Query: 233 RDRDRERE-RRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRR 291
R+R+RE E R+E +ER+ ER++ R R+R +R R R+KE R RER K + + +++
Sbjct: 39 REREREIETRKEGKKERESERKKER---REREKRKREREKE---RKRERGKKEKKGERKK 92
Query: 292 SSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRD 351
R R++ RRE+E KE G+ E + E G E K R+R
Sbjct: 93 EERERKKRRREKENKE------GEEKEKRK----------KKEKKERGRTSKEGKERERK 136
Query: 352 RERRRSHRSERERRR-DRDRDRDRDREHKR-----GERGSERGRDEAR 393
ER+R R ERER++ +R+++R+R KR GE+ ER E +
Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERK 184
Score = 83.2 bits (204), Expect = 4e-16
Identities = 58/174 (33%), Positives = 92/174 (52%), Gaps = 15/174 (8%)
Query: 231 RDRDRDRERERRERS---RERDKERERRR-------SRSRDRRRRSRSRDKEERRRSRER 280
++R+ +R++ERRER RER+KER+R R R ++ R R + R ++E + E+
Sbjct: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112
Query: 281 SKDKDRDRKRRSSRSRERARRER--ERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPD 338
K K +++K R S+E RER ERK E R E E + + E
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK-ERERKERKKRERKQV 171
Query: 339 GPDGPEEKGRDR-DRERRRSHRSERERRRDRDRDRDRDREH-KRGERGSERGRD 390
G E K ++R +R++R +R ER++ R+R R+R +E K+ ER ER +D
Sbjct: 172 GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKD 225
Score = 81.3 bits (199), Expect = 2e-15
Identities = 50/195 (25%), Positives = 96/195 (49%), Gaps = 22/195 (11%)
Query: 213 RDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDR-------RRR 265
R+ + + R R+++R RER ++E+ ER KE R+ R R++ + +
Sbjct: 55 RESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEK 114
Query: 266 SRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDA 325
+ ++K+ER R+ + K+++R +R+ +ER R++ ER++E E + G+
Sbjct: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK 174
Query: 326 PPDDGPPGELGPDGPDGPEEKGRDRDR-----ERRRSHRSER--ERRRDRDRDRDRDREH 378
+ + E K R+R+R ER R R ER ER++ +R ++R ++
Sbjct: 175 EEERKEK--------ERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR 226
Query: 379 KRGERGSERGRDEAR 393
+ R ERG+ E +
Sbjct: 227 QTNWREKERGKRERK 241
Score = 79.0 bits (193), Expect = 8e-15
Identities = 53/176 (30%), Positives = 88/176 (50%), Gaps = 21/176 (11%)
Query: 231 RDRDRD---RERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDK-DR 286
R+R+R+ R+ ++ER ER KER R R R+R + R R++ ++ + ER K++ +R
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKE-RKRERGKKEKKGERKKEERER 97
Query: 287 DRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEK 346
++RR ++E +E+ +K+E + G E E E + E K
Sbjct: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE-------ERKREERKERERK 150
Query: 347 GRDRDRERRRSHRSERER---------RRDRDRDRDRDREHKRGERGSERGRDEAR 393
+R++ER R R +RER R++++R + RE R ER ER R E R
Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR 206
Score = 65.9 bits (159), Expect = 7e-11
Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 68/262 (25%)
Query: 52 RDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVN 111
R+ TR E ++ER +++E+ ER +++ E E + +G+ R
Sbjct: 41 REREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGE--------RKK 92
Query: 112 YDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDG 171
+ K RRE E + +G++ +
Sbjct: 93 EERERKKRRREKE--------------------------------------NKEGEEKEK 114
Query: 172 RRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHR 231
R+ ERGRT K + R +++ R + + R
Sbjct: 115 RKKKEKKERGRTSKEGKERER--------------------KEERKREERKERERKKEER 154
Query: 232 DRDRDR-ERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKR 290
+++R+R ER++RER + +KE ER+ ++R++R R+R + ++ R R+ +++ ++RK+
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 291 RSSRSRERAR-RERERKEELRG 311
+ R +ER + R+ +E+ RG
Sbjct: 215 KEERKKERQKDRQTNWREKERG 236
Score = 65.5 bits (158), Expect = 9e-11
Identities = 63/274 (22%), Positives = 116/274 (42%), Gaps = 86/274 (31%)
Query: 46 REFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTL 105
RE E ++ +E ++ER ER++R++ ++++ E K +G+
Sbjct: 43 REIETRKEGKKERESERKKERREREKRKREREKERKRERGKK--------EKKGE----- 89
Query: 106 FVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHAD 165
R + K RRE E + +
Sbjct: 90 ---RKKEERERKKRRREKE--------------------------------------NKE 108
Query: 166 GKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGP 225
G++ + R+ ERGRT K + R +++ R + +
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKER--------------------ERKEERKREERKERE 148
Query: 226 SPLPHRDRDRDR-ERERRERSR-------ERDKERERRRSRSRDRRRRSRSRDKEERR-R 276
R+++R+R ER++RER + ++KER+ R+ R R+R+ R + R+++ERR R
Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
Query: 277 SRERSKDKDRDRKRRSSRS---RERARRERERKE 307
+ER K ++R ++R+ R RE+ R +RERKE
Sbjct: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 47.0 bits (110), Expect = 3e-05
Identities = 33/139 (23%), Positives = 58/139 (41%), Gaps = 43/139 (30%)
Query: 256 RSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGD 315
+S R+R R +R + ++ R ER K++ KR+ R +ER +RER +KE+
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKER-KRERGKKEK------- 86
Query: 316 MAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRD 375
KG ER++ R ++RRR+++ +
Sbjct: 87 ------------------------------KG-----ERKKEERERKKRRREKENKEGEE 111
Query: 376 REHKRGERGSERGRDEARG 394
+E ++ + ERGR G
Sbjct: 112 KEKRKKKEKKERGRTSKEG 130
Score = 33.9 bits (76), Expect = 0.30
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 19/83 (22%)
Query: 341 DGPEEKGRDRDRERRR--SHRSERERRRDRDR-----------------DRDRDREHKRG 381
+G +E+ +R +ERR + ERE+ R R+R R R++E+K G
Sbjct: 50 EGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEG 109
Query: 382 ERGSERGRDEARGGGGGQDNGLE 404
E +R + E + G G E
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKE 132
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 82.8 bits (203), Expect = 6e-16
Identities = 67/198 (33%), Positives = 93/198 (46%), Gaps = 24/198 (12%)
Query: 209 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERER---RERSRERDKERERRRSRSRDRRRR 265
RHS SR R PS HR R R R R R + RSR R K RRRS SR+R RR
Sbjct: 247 RHSRSRSRSR--RRRTPSSSRHR-RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRR 303
Query: 266 SRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDA 325
SRS K + + +DK++ R + +S ARR R E R S +G
Sbjct: 304 SRSTSKTRDK----KKEDKEKKRSKTPPKSYSTARRSRSASRERR------RRRSRSGTR 353
Query: 326 PPDD--GPPGEL--GPDGPDGPEEKGRDRDRERRRSHR----SERERRRDRDRDRDRDRE 377
P P +L P +EK +D+D+ER R R S++++ +D+++DR+R E
Sbjct: 354 SPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE 413
Query: 378 HKRGERGSERGRDEARGG 395
+ + R DE G
Sbjct: 414 SDKDVKQVTRDYDEEEQG 431
Score = 55.8 bits (133), Expect = 7e-08
Identities = 55/213 (25%), Positives = 86/213 (40%), Gaps = 21/213 (9%)
Query: 138 KRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLG 197
K+ K R R S+ +H + RR R K R RR
Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
Query: 198 GTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRER-------SRERDK 250
G RR + R ++D + + P R R RERR R S ++ +
Sbjct: 301 G-RRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPR 359
Query: 251 ERERRRSRS----RDRRRRSRSRDKEERRRSRERS-------KDKDRDRKRRSSRSRERA 299
+R+ SRS R ++ + + +DKE R RERS KDK++DR+R+S ++
Sbjct: 360 SPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVK 419
Query: 300 RRERERKEELRGGGGDMAEPSEAGDAPPDDGPP 332
+ R+ EE +G + + E P + G P
Sbjct: 420 QVTRDYDEEEQGYDSEKEKKEE--KKPIETGSP 450
Score = 50.4 bits (119), Expect = 3e-06
Identities = 51/199 (25%), Positives = 82/199 (41%), Gaps = 22/199 (11%)
Query: 138 KRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTV-KGWRP-RRLGGG 195
+RS PR E R S K D KK D + +R +T K + RR
Sbjct: 285 RRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK-----KRSKTPPKSYSTARRSRSA 339
Query: 196 LGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHR-----DRDRDRERERRERS----- 245
RR + R + + + PSP H+ D+D++R R+ RERS
Sbjct: 340 SRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKK 399
Query: 246 RERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERER 305
+ +DKE++R R D+ + +RD +E + + K+K ++K + S + E
Sbjct: 400 KSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVE- 458
Query: 306 KEELRGGGGDMAEPSEAGD 324
+G G + E GD
Sbjct: 459 ----KGTGDSLRESKVNGD 473
>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
Length = 238
Score = 82.4 bits (202), Expect = 7e-16
Identities = 72/262 (27%), Positives = 96/262 (36%), Gaps = 61/262 (23%)
Query: 105 LFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHA 164
++V + + +L R F YGP++ + + + P G+AF+E+E RD A +
Sbjct: 13 VYVGNLGTGAGKGELERAFSYYGPLRTVWIARN-----PPGFAFVEFEDPRDAEDAVRGL 67
Query: 165 DGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPG 224
DGK I G RV V++ G PRR SR+D P
Sbjct: 68 DGKVICGSRVRVELSTG------MPRR-------------------------SRFDRPPA 96
Query: 225 PSPLPHRDRDRD---------------RERERRERSRERDKERERRRSRSRDRRRRSRSR 269
P DR + R R R RSR + R RR SRSR R R RSR
Sbjct: 97 RRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSR 156
Query: 270 DKEER-------RRSRERSKDKDRDRKRRSSRSRERARRERERKEEL---RGGGGDMAEP 319
R RRSR S + R + SR + R R R + R P
Sbjct: 157 SASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSP 216
Query: 320 SEAGDAPPDDGPPGELGPDGPD 341
S P P P+ D
Sbjct: 217 SPKRSRSPSGSPRRSASPERMD 238
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 82.0 bits (201), Expect = 1e-15
Identities = 87/372 (23%), Positives = 139/372 (37%), Gaps = 75/372 (20%)
Query: 105 LFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHA 164
+++ R++Y E + R F+ YG I + + GY F+E++ RD A
Sbjct: 4 VYIGRLSYQARERDVERFFKGYGKILEVDL--------KNGYGFVEFDDLRDADDAVYEL 55
Query: 165 DGKKIDGRRVLVDVER--------GRTVKGWRPRRLGGGLGGT----------------- 199
+GK + G RV+V+ R G G+ RR G G
Sbjct: 56 NGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRC 115
Query: 200 ----------RRGGADVNIRHSGR-----------DDTSRYDERPGPSPLPHRD----RD 234
+ G H GR D R E+ + + R D
Sbjct: 116 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED 175
Query: 235 RDRERERRERSRERDKERERRRSRS--RDRRRRSRSRDKEERRRSRERSKDKDRDRKRRS 292
+ R RR SR R R R RSR + R R S+ + RSR RS + R + R
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR 235
Query: 293 SRSRERARRERER---KEELR-----GGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPE 344
S+SR R+++E+ R KE+ R G +A + ++ G+ P
Sbjct: 236 SQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGK--PKSRSPSR 293
Query: 345 EKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRG-----ERGSERGRDEARGGGGGQ 399
K + + R R + R E E+R R R +++ ++ +G R R +R +
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK 353
Query: 400 DNGLEGLGNDSR 411
G + +SR
Sbjct: 354 RKGRKRSREESR 365
Score = 71.6 bits (174), Expect = 1e-12
Identities = 60/203 (29%), Positives = 87/203 (42%), Gaps = 45/203 (22%)
Query: 226 SPLPHRDRDRDRERERRERSRERDKERERRRSRSRD---RRRRSRSRDK---EERRRSRE 279
SP H+ + + R R + ER E +K R RS++ R+ RSRSR K R RSR
Sbjct: 290 SPSRHKSKSKSRSRSQ-ERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS 348
Query: 280 RSKDKDRDRKRRS----SRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGEL 335
+SKDK + RKR SRSR R++ ER RK RG D S+AG +
Sbjct: 349 KSKDKRKGRKRSREESRSRSRSRSKSERSRK---RGSKRD----SKAGSS---------- 391
Query: 336 GPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGG 395
++++ ++R + R R ++REH + E GR E+
Sbjct: 392 -----------------KKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENA 434
Query: 396 GGGQDNGLEGLGNDSRDMYMESE 418
G Q+ N + SE
Sbjct: 435 GTNQETRSRSRSNSKSKPNLPSE 457
Score = 70.1 bits (170), Expect = 4e-12
Identities = 42/150 (28%), Positives = 66/150 (44%), Gaps = 3/150 (2%)
Query: 231 RDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKR 290
R + +D+ R+ R+RSRE + R R RS+S R+R RD + +++ +D DR + R
Sbjct: 347 RSKSKDK-RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405
Query: 291 RSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDR 350
SRS + R + + R G G+ + + P+ P E + R +
Sbjct: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPS--ESRSRSK 463
Query: 351 DRERRRSHRSERERRRDRDRDRDRDREHKR 380
+ RS R R R R R R H R
Sbjct: 464 SASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 47.0 bits (110), Expect = 3e-05
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 11/114 (9%)
Query: 198 GTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRS 257
G++R + + ++DT R R P R ++RE + E S+ +
Sbjct: 381 GSKRDSKAGSSKKKKKEDTDRSQSRS-----PSRSVSKEREHAKSESSQREGRGESENAG 435
Query: 258 RSRDRRRRSRSRDKEERR---RSRERSKDKDRDRKRRSSRSRERAR---RERER 305
+++ R RSRS K + SR RSK + R R SRSR +R R R R
Sbjct: 436 TNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 4/96 (4%)
Query: 217 SRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDK--EER 274
S+ D + G S ++ D DR + R SR KERE +S S R R S + +
Sbjct: 382 SKRDSKAGSSKKKKKE-DTDRSQSRSP-SRSVSKEREHAKSESSQREGRGESENAGTNQE 439
Query: 275 RRSRERSKDKDRDRKRRSSRSRERARRERERKEELR 310
RSR RS K + SRSR ++ + + + R
Sbjct: 440 TRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSR 475
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 82.0 bits (201), Expect = 1e-15
Identities = 80/327 (24%), Positives = 123/327 (37%), Gaps = 72/327 (22%)
Query: 105 LFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHA 164
+++ R++Y+ E ++R F YG + + + GY F+E+E RD A
Sbjct: 4 VYIGRLSYNVREKDIQRFFSGYGRLLEVDL--------KNGYGFVEFEDSRDADDAVYEL 55
Query: 165 DGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLG-GTRRGGADVNIRH-SGRD-------- 214
+GK++ G RV+V+ RG PRR G G+R GG + R SGRD
Sbjct: 56 NGKELCGERVIVEHARG-------PRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRT 108
Query: 215 ----------------DTSRYDERPGPSPLPHRDRDRDRE-----RERRERSRERDK--- 250
D + + G ++R E R + R DK
Sbjct: 109 EYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDG 168
Query: 251 -ERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEEL 309
E R R + + R+ R RSR RS+ + R R RRSSRSR R+ + +
Sbjct: 169 TEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRS 228
Query: 310 RGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRD-- 367
R G + K + + + R SH R R +D
Sbjct: 229 RSKGRSRSRSKGRKS-------------------RSKSKSKPKSDRGSHSHSRSRSKDEY 269
Query: 368 -RDRDRDRDREHKRGERGSERGRDEAR 393
+ R R R R K +G + + +R
Sbjct: 270 EKSRSRSRSRSPKENGKGDIKSKSRSR 296
Score = 68.2 bits (165), Expect = 1e-11
Identities = 57/186 (30%), Positives = 80/186 (43%), Gaps = 19/186 (10%)
Query: 196 LGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERR 255
L GT G ++ + +D R R S R R R R R R RS R + R
Sbjct: 166 LDGTEINGRNIRLI----EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRS-SRSRSRSIS 220
Query: 256 RSRSRDRRR-RSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERER-------KE 307
+SRSR R R + RSR + + R+SR +SK K + + S SR R++ E E+ +
Sbjct: 221 KSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280
Query: 308 ELRGGGGDMAEP----SEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERE 363
G GD+ S++ P PP + P P ++ R R R RS R
Sbjct: 281 PKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSP--PPKRATSRSRSRSRSKSRSRS 338
Query: 364 RRRDRD 369
R RD
Sbjct: 339 RSSSRD 344
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 80.5 bits (197), Expect = 3e-15
Identities = 43/135 (31%), Positives = 69/135 (51%), Gaps = 5/135 (3%)
Query: 230 HRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRK 289
H R+R+RERER R RER++ERER R R R +R R R R+ E + + R ++ +R+R
Sbjct: 399 HNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERA 458
Query: 290 RRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRD 349
+R + R+ R+RE++ E G +P PP GP+ K D
Sbjct: 459 KRDEKDRQHRDRDREKEREKEKG-----KPKPRSPQPPSRQAEPPKKEAATTGPQVKRAD 513
Query: 350 RDRERRRSHRSERER 364
++ R +S +++
Sbjct: 514 EWKDPWRRSKSPKKK 528
Score = 68.2 bits (165), Expect = 1e-11
Identities = 56/207 (27%), Positives = 90/207 (43%), Gaps = 26/207 (12%)
Query: 201 RGGADVNIR---------HSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKE 251
RGG N R H+ R+ R ER R+R+RDRERERR+R RER++E
Sbjct: 381 RGGQYENFRVQYTETEPYHNYRE-RERERERENRQRERERERERDRERERRQRERERERE 439
Query: 252 RERRRSRSRDR----RRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKE 307
ER + R R + R R++ +K+ + R R+R K++++++ + RS + R+ E +
Sbjct: 440 HERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPK 499
Query: 308 ELRGGGGDMAEPSEAGDAP--PDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERR 365
+ G + ++ P P +LG R R RR++ S
Sbjct: 500 KEAATTGPQVKRADEWKDPWRRSKSPKKKLG-------VSVSPSRARRRRKTSASSASA- 551
Query: 366 RDRDRDRDRDREHKRGERGSERGRDEA 392
+ R R GS R R +
Sbjct: 552 --SNSSRSSSRSSSYSGSGSSRSRSRS 576
Score = 60.1 bits (144), Expect = 4e-09
Identities = 44/154 (28%), Positives = 69/154 (44%), Gaps = 37/154 (24%)
Query: 229 PHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDR 288
P+ D D E ER R + + R + R R R++E R RER ++++RDR
Sbjct: 366 PYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDR 425
Query: 289 KRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGR 348
+ RER +RERER+ E E + R
Sbjct: 426 E------RERRQRERERERE------------------------------HERDKERQRR 449
Query: 349 DRDRERRRSHRSERERRRDRDRDRDRDREHKRGE 382
+ ER R+ R E++R+ RDRDR+++RE ++G+
Sbjct: 450 KEEWERERAKRDEKDRQH-RDRDREKEREKEKGK 482
Score = 49.7 bits (117), Expect = 5e-06
Identities = 24/51 (47%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Query: 343 PEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEAR 393
P R+R+RER R +R +RER R+R+RDR+R+R + ER E RD+ R
Sbjct: 397 PYHNYRERERERERENR-QRERERERERDRERERRQREREREREHERDKER 446
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/51 (43%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
Query: 344 EEKGRDRDRERRRSHRSERERR-RDRDRDRDRDREHKRGERGSERGRDEAR 393
E + R R+RER R ERERR R+R+R+R+ +R+ +R R E R+ A+
Sbjct: 409 ERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAK 459
Score = 38.1 bits (87), Expect = 0.016
Identities = 44/155 (28%), Positives = 52/155 (33%), Gaps = 12/155 (7%)
Query: 224 GPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKE----ERRRSRE 279
G S P R R R + + + R S S RSRSR R SR
Sbjct: 530 GVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRH 589
Query: 280 RSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGD------APPDDGPPG 333
S R R R S S + + +R G P +AG+ APP PP
Sbjct: 590 SSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPP-PAPPQ 648
Query: 334 ELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDR 368
P PE RE RR R R R R
Sbjct: 649 ATKTTAP-VPEPTKPGDPREARRKERPARTPPRRR 682
Score = 36.2 bits (82), Expect = 0.060
Identities = 31/138 (22%), Positives = 54/138 (39%), Gaps = 14/138 (10%)
Query: 259 SRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAE 318
S R + ++ ++E+ +S++ K+ RKR SS ++ + GG +
Sbjct: 741 SASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPP-------AGGKSSQQ 793
Query: 319 PSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREH 378
PS P PPG+ P K + + + R+R D+DR
Sbjct: 794 PST-----PQQAPPGQ--PQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPA 846
Query: 379 KRGERGSERGRDEARGGG 396
KR +RG + + GG
Sbjct: 847 KRPNTSPDRGSRDRKSGG 864
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 80.1 bits (196), Expect = 4e-15
Identities = 81/300 (27%), Positives = 103/300 (34%), Gaps = 38/300 (12%)
Query: 95 PNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHE 154
P D TL V + Y T+ LRR FE YG + +++ + PRG+AF+ +
Sbjct: 6 PPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDR 65
Query: 155 RDMHSAYKHADGKKIDGRRVLVDVER-GRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGR 213
RD A DG ++DGR + V V R GR + R G G +R GG R GR
Sbjct: 66 RDAQDAEAAMDGAELDGRELRVQVARYGR--RDLPRSRQGEPRGRSRGGGYGRRSRSYGR 123
Query: 214 DDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEE 273
R R RR RSR R R RSRSR R R
Sbjct: 124 ---------------------RSRSPRRRHRSRSRGPSCSRSRSRSRYRGSR-------- 154
Query: 274 RRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPG 333
RS R R RS SR R R R G + S +
Sbjct: 155 YSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSS------RS 208
Query: 334 ELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEAR 393
+ RRS S R R R R R R + + R ++
Sbjct: 209 HSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSK 268
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.137 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,307,371
Number of Sequences: 37866
Number of extensions: 1279213
Number of successful extensions: 46254
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 976
Number of HSP's successfully gapped in prelim test: 770
Number of HSP's that attempted gapping in prelim test: 9786
Number of HSP's gapped (non-prelim): 15171
length of query: 437
length of database: 18,247,518
effective HSP length: 105
effective length of query: 332
effective length of database: 14,271,588
effective search space: 4738167216
effective search space used: 4738167216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.