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Search of human proteins with 122937279
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937279 tetratricopeptide repeat domain 36 [Homo sapiens]
(189 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937279 tetratricopeptide repeat domain 36 [Homo sapiens] 369 e-103
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 43 1e-04
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 42 2e-04
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 42 4e-04
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 41 5e-04
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 41 5e-04
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 40 0.001
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 40 0.001
gi|56606133 tetratricopeptide repeat domain 32 [Homo sapiens] 40 0.002
gi|238859655 tetratricopeptide repeat domain 31 [Homo sapiens] 39 0.003
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 38 0.006
gi|27262638 sperm associated antigen 1 [Homo sapiens] 36 0.023
gi|27262636 sperm associated antigen 1 [Homo sapiens] 36 0.023
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 35 0.038
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 35 0.038
gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled... 34 0.086
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 34 0.086
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 33 0.11
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 33 0.11
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 33 0.11
gi|126362955 sodium channel, voltage-gated, type III, alpha isof... 33 0.11
gi|126362947 sodium channel, voltage-gated, type III, alpha isof... 33 0.11
gi|126362949 sodium channel, voltage-gated, type III, alpha isof... 33 0.11
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 33 0.19
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 32 0.25
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 32 0.25
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 32 0.25
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 32 0.33
gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 32 0.33
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 32 0.33
>gi|122937279 tetratricopeptide repeat domain 36 [Homo sapiens]
Length = 189
Score = 369 bits (947), Expect = e-103
Identities = 189/189 (100%), Positives = 189/189 (100%)
Query: 1 MGTPNDQAVLQAIFNPDTPFGDIVGLDLGEEAEKEEREEDEVFPQAQLEQSKALELQGVM 60
MGTPNDQAVLQAIFNPDTPFGDIVGLDLGEEAEKEEREEDEVFPQAQLEQSKALELQGVM
Sbjct: 1 MGTPNDQAVLQAIFNPDTPFGDIVGLDLGEEAEKEEREEDEVFPQAQLEQSKALELQGVM 60
Query: 61 AAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGR 120
AAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGR
Sbjct: 61 AAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGR 120
Query: 121 AARQSFVQRGLLARLQGRDDDARRDFERAARLGSPFARRQLVLLNPYAALCNRMLADMMG 180
AARQSFVQRGLLARLQGRDDDARRDFERAARLGSPFARRQLVLLNPYAALCNRMLADMMG
Sbjct: 121 AARQSFVQRGLLARLQGRDDDARRDFERAARLGSPFARRQLVLLNPYAALCNRMLADMMG 180
Query: 181 QLRRPRDSR 189
QLRRPRDSR
Sbjct: 181 QLRRPRDSR 189
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 43.1 bits (100), Expect = 1e-04
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
Query: 48 LEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALED 107
+EQ L+ +G A G++ AL+ + +AI L P Y+NR+ A +GD A ED
Sbjct: 1 MEQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYED 60
Query: 108 LERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRDFERAAR 151
+ V+L G+ + ++ R ++A+R +E +
Sbjct: 61 GCKTVDLKPDWGK----GYSRKAAALEFLNRFEEAKRTYEEGLK 100
Score = 33.1 bits (74), Expect = 0.15
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 7/88 (7%)
Query: 30 EEAEKEEREEDE---VFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERAS 86
++AEK +E++ + P LE+ +G + GD A++ + +AI P+ A
Sbjct: 340 QQAEKILKEQERLAYINPDLALEEKN----KGNECFQKGDYPQAMKHYTEAIKRNPKDAK 395
Query: 87 AYNNRAQARRLQGDVAGALEDLERAVEL 114
Y+NRA + AL+D E ++L
Sbjct: 396 LYSNRAACYTKLLEFQLALKDCEECIQL 423
Score = 32.7 bits (73), Expect = 0.19
Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 21/127 (16%)
Query: 18 TPFGDIVGLDLGEEAEKEE----------------REEDEVFPQAQLEQSKALELQGVMA 61
T ++G+DLG E+EE +E P+ + + K EL G A
Sbjct: 177 TTLSVLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKEL-GNDA 235
Query: 62 AEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRA 121
+ D TAL+ + +A L P + N+A +GD E E+A+E+ GR
Sbjct: 236 YKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEV----GRE 291
Query: 122 ARQSFVQ 128
R+ + Q
Sbjct: 292 NREDYRQ 298
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 42.4 bits (98), Expect = 2e-04
Identities = 36/100 (36%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Query: 52 KALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERA 111
K LEL G AG L+ AL +F A+ P+ AY RA G AL DL +
Sbjct: 39 KHLEL-GKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKV 97
Query: 112 VELSGGRGRAARQSFVQRGLLARLQGRDDDARRDFERAAR 151
++L AAR +QRG L QG+ D+A DF++ +
Sbjct: 98 IQLKMDF-TAAR---LQRGHLLLKQGKLDEAEDDFKKVLK 133
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 41.6 bits (96), Expect = 4e-04
Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 4/124 (3%)
Query: 29 GEEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAY 88
GE E E DE L++++ L+ Q +A D A++ + QAI L P A Y
Sbjct: 6 GERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYY 65
Query: 89 NNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRDFER 148
NR+ A AL D RA+EL + + + +R G+ A RD+E
Sbjct: 66 GNRSLAYLRTECYGYALGDATRAIELD----KKYIKGYYRRAASNMALGKFRAALRDYET 121
Query: 149 AARL 152
++
Sbjct: 122 VVKV 125
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 41.2 bits (95), Expect = 5e-04
Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 30 EEAEKEEREEDEVFPQ-AQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAY 88
EEA + R+ EVFP+ A + A LQ + G L AL + +AI + P A AY
Sbjct: 334 EEAVRLYRKALEVFPEFAAAHSNLASVLQ-----QQGKLQEALMHYKEAIRISPTFADAY 388
Query: 89 NNRAQARRLQGDVAGALEDLERAVELS 115
+N + DV GAL+ RA++++
Sbjct: 389 SNMGNTLKEMQDVQGALQCYTRAIQIN 415
Score = 38.5 bits (88), Expect = 0.003
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 11/132 (8%)
Query: 26 LDLGEEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERA 85
+DL + + E FP A + AL+ E G ++ A + + A+ L P A
Sbjct: 265 IDLAIDTYRRAIELQPHFPDAYCNLANALK-------EKGSVAEAEDCYNTALRLCPTHA 317
Query: 86 SAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRD 145
+ NN A +R QG++ A+ +A+E+ AA + + + QG+ +A
Sbjct: 318 DSLNNLANIKREQGNIEEAVRLYRKALEVF-PEFAAAHSNLAS---VLQQQGKLQEALMH 373
Query: 146 FERAARLGSPFA 157
++ A R+ FA
Sbjct: 374 YKEAIRISPTFA 385
Score = 31.6 bits (70), Expect = 0.43
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 58 GVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVE 113
G + E G L A+E + A+ L P+ Y N A A GD+ GA++ A++
Sbjct: 86 GNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQ 141
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 41.2 bits (95), Expect = 5e-04
Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 30 EEAEKEEREEDEVFPQ-AQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAY 88
EEA + R+ EVFP+ A + A LQ + G L AL + +AI + P A AY
Sbjct: 344 EEAVRLYRKALEVFPEFAAAHSNLASVLQ-----QQGKLQEALMHYKEAIRISPTFADAY 398
Query: 89 NNRAQARRLQGDVAGALEDLERAVELS 115
+N + DV GAL+ RA++++
Sbjct: 399 SNMGNTLKEMQDVQGALQCYTRAIQIN 425
Score = 38.5 bits (88), Expect = 0.003
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 11/132 (8%)
Query: 26 LDLGEEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERA 85
+DL + + E FP A + AL+ E G ++ A + + A+ L P A
Sbjct: 275 IDLAIDTYRRAIELQPHFPDAYCNLANALK-------EKGSVAEAEDCYNTALRLCPTHA 327
Query: 86 SAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRD 145
+ NN A +R QG++ A+ +A+E+ AA + + + QG+ +A
Sbjct: 328 DSLNNLANIKREQGNIEEAVRLYRKALEVF-PEFAAAHSNLAS---VLQQQGKLQEALMH 383
Query: 146 FERAARLGSPFA 157
++ A R+ FA
Sbjct: 384 YKEAIRISPTFA 395
Score = 31.6 bits (70), Expect = 0.43
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 58 GVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVE 113
G + E G L A+E + A+ L P+ Y N A A GD+ GA++ A++
Sbjct: 96 GNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQ 151
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 40.0 bits (92), Expect = 0.001
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 7/86 (8%)
Query: 27 DLGEEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERAS 86
DL A EED +++ L+ +G + + A+ +G+AI L P A
Sbjct: 74 DLRSPARTPPSEEDSA-------EAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAV 126
Query: 87 AYNNRAQARRLQGDVAGALEDLERAV 112
+ NRA A G+ AGA++D ERA+
Sbjct: 127 YFCNRAAAYSKLGNYAGAVQDCERAI 152
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 40.0 bits (92), Expect = 0.001
Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 22 DIVGLDLGEE--AEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAI- 78
D+ +L EE E E+ DE Q + E+S L+ +G + GD A + +A+
Sbjct: 86 DVNSSELDEEYLIELEKNMSDEE-KQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALE 144
Query: 79 ----CLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLAR 134
C ER+ ++NRA AR Q A+ D +A++L+ RA ++R L
Sbjct: 145 MCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRA----ILRRAELYE 200
Query: 135 LQGRDDDARRDFE 147
+ D+A D++
Sbjct: 201 KTDKLDEALEDYK 213
>gi|56606133 tetratricopeptide repeat domain 32 [Homo sapiens]
Length = 151
Score = 39.7 bits (91), Expect = 0.002
Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 6/135 (4%)
Query: 31 EAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTAL--ERFGQAICLLPERASAY 88
E +++E QA + E + + +A + A + + C + A+AY
Sbjct: 2 EGQRQESHATLTLAQAHFNNGEYAEAEALYSAYIRRCACAASSDESPGSKCSPEDLATAY 61
Query: 89 NNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRDFER 148
NNR Q + + D A++D A+E+ + RGL+ G DDA DF++
Sbjct: 62 NNRGQIKYFRVDFYEAMDDYTSAIEVQPN----FEVPYYNRGLILYRLGYFDDALEDFKK 117
Query: 149 AARLGSPFARRQLVL 163
L F L L
Sbjct: 118 VLDLNPGFQDATLSL 132
>gi|238859655 tetratricopeptide repeat domain 31 [Homo sapiens]
Length = 519
Score = 38.5 bits (88), Expect = 0.003
Identities = 46/145 (31%), Positives = 63/145 (43%), Gaps = 15/145 (10%)
Query: 28 LGEEAEKEEREE-DEVFPQAQ---------LEQSKALELQGVMAAEAGDLSTALERFGQA 77
+G+E E REE + P+ Q L+QS+ L G A+ G A+ F QA
Sbjct: 272 MGQEEESPPREERPQQSPKVQASPGLLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQA 331
Query: 78 ICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQG 137
+ L P+ + NR+ G A AL D + A+ L G R F L LQ
Sbjct: 332 LKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGL---FRLGKALMGLQ- 387
Query: 138 RDDDARRDFERAARLGS-PFARRQL 161
R +A F+ R GS P A R+L
Sbjct: 388 RFREAAAVFQETLRGGSQPDAAREL 412
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 37.7 bits (86), Expect = 0.006
Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 16/122 (13%)
Query: 28 LGEEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASA 87
L E+ EK+E E + + + EQ+ ++LQ + +L +E G+ I ERAS
Sbjct: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQ----KKIKELQARIEELGEEI--EAERAS- 1131
Query: 88 YNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRDFE 147
RA+A + + D++ LE++ +E +GG A Q L + + RRD E
Sbjct: 1132 ---RAKAEKQRSDLSRELEEISERLEEAGGATSA------QVELNKKREAEFQKLRRDLE 1182
Query: 148 RA 149
A
Sbjct: 1183 EA 1184
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 35.8 bits (81), Expect = 0.023
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 5/92 (5%)
Query: 57 QGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSG 116
+G A +GD A+ + ++I LP AYNNRAQA + A +D E+ +EL
Sbjct: 215 KGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEP 273
Query: 117 GRGRAARQSFVQRGLLARLQGRDDDARRDFER 148
G +A ++R + Q + +A D +
Sbjct: 274 GNVKA----LLRRATTYKHQNKLREATEDLSK 301
Score = 29.6 bits (65), Expect = 1.6
Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 52 KALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERA 111
KAL+ +G + AL ++ + + + + + Y NRA A +D ++A
Sbjct: 624 KALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQA 683
Query: 112 VELSGGRGRA-ARQSFVQRGL 131
++L+ G +A R++ +GL
Sbjct: 684 LQLADGNVKAFYRRALAHKGL 704
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 35.8 bits (81), Expect = 0.023
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 5/92 (5%)
Query: 57 QGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSG 116
+G A +GD A+ + ++I LP AYNNRAQA + A +D E+ +EL
Sbjct: 215 KGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEP 273
Query: 117 GRGRAARQSFVQRGLLARLQGRDDDARRDFER 148
G +A ++R + Q + +A D +
Sbjct: 274 GNVKA----LLRRATTYKHQNKLREATEDLSK 301
Score = 29.6 bits (65), Expect = 1.6
Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 52 KALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERA 111
KAL+ +G + AL ++ + + + + + Y NRA A +D ++A
Sbjct: 624 KALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQA 683
Query: 112 VELSGGRGRA-ARQSFVQRGL 131
++L+ G +A R++ +GL
Sbjct: 684 LQLADGNVKAFYRRALAHKGL 704
>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
sapiens]
Length = 807
Score = 35.0 bits (79), Expect = 0.038
Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 20/134 (14%)
Query: 45 QAQLEQSK----ALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGD 100
Q LE +K A+ +G+ G L A+E F +A+ + AY + QA R G+
Sbjct: 220 QQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGN 279
Query: 101 VAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRDFERAARLGSPFARRQ 160
A E ++A+ L+ Q+ RG++ G +A ++F+R +
Sbjct: 280 FEAATESFQKALLLNQNH----VQTLQLRGMMLYHHGSLQEALKNFKRCLQ--------- 326
Query: 161 LVLLNPYAALCNRM 174
L PY +C M
Sbjct: 327 ---LEPYNEVCQYM 337
>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
sapiens]
Length = 860
Score = 35.0 bits (79), Expect = 0.038
Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 20/134 (14%)
Query: 45 QAQLEQSK----ALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGD 100
Q LE +K A+ +G+ G L A+E F +A+ + AY + QA R G+
Sbjct: 273 QQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGN 332
Query: 101 VAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRDFERAARLGSPFARRQ 160
A E ++A+ L+ Q+ RG++ G +A ++F+R +
Sbjct: 333 FEAATESFQKALLLNQNH----VQTLQLRGMMLYHHGSLQEALKNFKRCLQ--------- 379
Query: 161 LVLLNPYAALCNRM 174
L PY +C M
Sbjct: 380 ---LEPYNEVCQYM 390
Score = 30.4 bits (67), Expect = 0.95
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 5/83 (6%)
Query: 70 ALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQR 129
AL + I L P+R + RA+ G + A+ DL +A++L + + + + R
Sbjct: 201 ALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQL-----QPSARLYRHR 255
Query: 130 GLLARLQGRDDDARRDFERAARL 152
G L + A DF+++ L
Sbjct: 256 GTLYFISEDYATAHEDFQQSLEL 278
>gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 2 [Homo sapiens]
Length = 1990
Score = 33.9 bits (76), Expect = 0.086
Identities = 20/49 (40%), Positives = 27/49 (55%)
Query: 66 DLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVEL 114
D A E +A+ L P+ AY RA+A+R A ALEDL A++L
Sbjct: 1306 DFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKL 1354
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 33.9 bits (76), Expect = 0.086
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Query: 68 STALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFV 127
+ A++ + QAI L P A Y NRA A+ G A++D E+A+ + +A +
Sbjct: 102 AAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKA----YG 157
Query: 128 QRGLLARLQGRDDDARRDFERAARL 152
+ GL + ++A +++A L
Sbjct: 158 RMGLALTALNKFEEAVTSYQKALDL 182
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 33.5 bits (75), Expect = 0.11
Identities = 42/120 (35%), Positives = 49/120 (40%), Gaps = 29/120 (24%)
Query: 60 MAAEAGDLSTALERFGQAICLLPERASAYNNRAQA-----RRLQGDVAGALEDLERAVEL 114
M AEA L LE A ERA AQA RR Q + AGALE E A
Sbjct: 1366 MEAEAAGLREQLEEEAAA----RERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEA--- 1418
Query: 115 SGGRGRAARQSFVQRGLLA--------------RLQGRDDDARRDFERAARLGSPFARRQ 160
R RAAR++ LA RLQ DDA D E+ +L S ++Q
Sbjct: 1419 ---RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQ 1475
Score = 31.6 bits (70), Expect = 0.43
Identities = 43/145 (29%), Positives = 73/145 (50%), Gaps = 29/145 (20%)
Query: 31 EAEKEEREEDEVFPQAQLEQSKAL--ELQGVMAAEAGDLSTALERFGQAICLLPERASAY 88
E E+E REE E Q++AL EL+ +++++ D+ ++ +A C + E+A A
Sbjct: 1518 EEEQEAREELE-------RQNRALRAELEALLSSK-DDVGKSVHELERA-CRVAEQA-AN 1567
Query: 89 NNRAQARRLQGDVAGALEDLERAVELS------------GGRGRAARQSFVQRGLLARLQ 136
+ RAQ L+ ++ A ED + +E++ GR A + +R LA+ Q
Sbjct: 1568 DLRAQVTELEDELTAA-EDAKLRLEVTVQALKTQHERDLQGRDEAGEE---RRRQLAK-Q 1622
Query: 137 GRDDDARRDFERAARLGSPFARRQL 161
RD + RD ER R + AR++L
Sbjct: 1623 LRDAEVERDEERKQRTLAVAARKKL 1647
Score = 28.9 bits (63), Expect = 2.8
Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 4/117 (3%)
Query: 39 EDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNR-AQARRL 97
+DEV E K ELQ A E G+L + + + L E+ A A+A
Sbjct: 875 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 934
Query: 98 QGDVAGALEDLERAV-ELSGGRGRAARQSFVQRGLLARLQG--RDDDARRDFERAAR 151
+G +A ++LE V EL G S + RLQ ++ +A + E AR
Sbjct: 935 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGAR 991
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 33.5 bits (75), Expect = 0.11
Identities = 42/120 (35%), Positives = 49/120 (40%), Gaps = 29/120 (24%)
Query: 60 MAAEAGDLSTALERFGQAICLLPERASAYNNRAQA-----RRLQGDVAGALEDLERAVEL 114
M AEA L LE A ERA AQA RR Q + AGALE E A
Sbjct: 1358 MEAEAAGLREQLEEEAAA----RERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEA--- 1410
Query: 115 SGGRGRAARQSFVQRGLLA--------------RLQGRDDDARRDFERAARLGSPFARRQ 160
R RAAR++ LA RLQ DDA D E+ +L S ++Q
Sbjct: 1411 ---RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQ 1467
Score = 31.6 bits (70), Expect = 0.43
Identities = 43/145 (29%), Positives = 73/145 (50%), Gaps = 29/145 (20%)
Query: 31 EAEKEEREEDEVFPQAQLEQSKAL--ELQGVMAAEAGDLSTALERFGQAICLLPERASAY 88
E E+E REE E Q++AL EL+ +++++ D+ ++ +A C + E+A A
Sbjct: 1510 EEEQEAREELE-------RQNRALRAELEALLSSK-DDVGKSVHELERA-CRVAEQA-AN 1559
Query: 89 NNRAQARRLQGDVAGALEDLERAVELS------------GGRGRAARQSFVQRGLLARLQ 136
+ RAQ L+ ++ A ED + +E++ GR A + +R LA+ Q
Sbjct: 1560 DLRAQVTELEDELTAA-EDAKLRLEVTVQALKTQHERDLQGRDEAGEE---RRRQLAK-Q 1614
Query: 137 GRDDDARRDFERAARLGSPFARRQL 161
RD + RD ER R + AR++L
Sbjct: 1615 LRDAEVERDEERKQRTLAVAARKKL 1639
Score = 28.9 bits (63), Expect = 2.8
Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 4/117 (3%)
Query: 39 EDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNR-AQARRL 97
+DEV E K ELQ A E G+L + + + L E+ A A+A
Sbjct: 867 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 926
Query: 98 QGDVAGALEDLERAV-ELSGGRGRAARQSFVQRGLLARLQG--RDDDARRDFERAAR 151
+G +A ++LE V EL G S + RLQ ++ +A + E AR
Sbjct: 927 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGAR 983
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 33.5 bits (75), Expect = 0.11
Identities = 42/120 (35%), Positives = 49/120 (40%), Gaps = 29/120 (24%)
Query: 60 MAAEAGDLSTALERFGQAICLLPERASAYNNRAQA-----RRLQGDVAGALEDLERAVEL 114
M AEA L LE A ERA AQA RR Q + AGALE E A
Sbjct: 1399 MEAEAAGLREQLEEEAAA----RERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEA--- 1451
Query: 115 SGGRGRAARQSFVQRGLLA--------------RLQGRDDDARRDFERAARLGSPFARRQ 160
R RAAR++ LA RLQ DDA D E+ +L S ++Q
Sbjct: 1452 ---RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQ 1508
Score = 31.6 bits (70), Expect = 0.43
Identities = 43/145 (29%), Positives = 73/145 (50%), Gaps = 29/145 (20%)
Query: 31 EAEKEEREEDEVFPQAQLEQSKAL--ELQGVMAAEAGDLSTALERFGQAICLLPERASAY 88
E E+E REE E Q++AL EL+ +++++ D+ ++ +A C + E+A A
Sbjct: 1551 EEEQEAREELE-------RQNRALRAELEALLSSK-DDVGKSVHELERA-CRVAEQA-AN 1600
Query: 89 NNRAQARRLQGDVAGALEDLERAVELS------------GGRGRAARQSFVQRGLLARLQ 136
+ RAQ L+ ++ A ED + +E++ GR A + +R LA+ Q
Sbjct: 1601 DLRAQVTELEDELTAA-EDAKLRLEVTVQALKTQHERDLQGRDEAGEE---RRRQLAK-Q 1655
Query: 137 GRDDDARRDFERAARLGSPFARRQL 161
RD + RD ER R + AR++L
Sbjct: 1656 LRDAEVERDEERKQRTLAVAARKKL 1680
Score = 28.9 bits (63), Expect = 2.8
Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 4/117 (3%)
Query: 39 EDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNR-AQARRL 97
+DEV E K ELQ A E G+L + + + L E+ A A+A
Sbjct: 908 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 967
Query: 98 QGDVAGALEDLERAV-ELSGGRGRAARQSFVQRGLLARLQG--RDDDARRDFERAAR 151
+G +A ++LE V EL G S + RLQ ++ +A + E AR
Sbjct: 968 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGAR 1024
>gi|126362955 sodium channel, voltage-gated, type III, alpha isoform
3 [Homo sapiens]
Length = 1951
Score = 33.5 bits (75), Expect = 0.11
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 5/103 (4%)
Query: 30 EEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEA-----GDLSTALERFGQAICLLPER 84
EEAE++E E ++ Q + +Q +A + AA G L LE +A L +
Sbjct: 436 EEAEQKEAEFQQMLEQLKKQQEEAQAVAAASAASRDFSGIGGLGELLESSSEASKLSSKS 495
Query: 85 ASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFV 127
A + NR + RR + + G + + S R SF+
Sbjct: 496 AKEWRNRRKKRRQREHLEGNNKGERDSFPKSESEDSVKRSSFL 538
>gi|126362947 sodium channel, voltage-gated, type III, alpha isoform
2 [Homo sapiens]
Length = 1951
Score = 33.5 bits (75), Expect = 0.11
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 5/103 (4%)
Query: 30 EEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEA-----GDLSTALERFGQAICLLPER 84
EEAE++E E ++ Q + +Q +A + AA G L LE +A L +
Sbjct: 436 EEAEQKEAEFQQMLEQLKKQQEEAQAVAAASAASRDFSGIGGLGELLESSSEASKLSSKS 495
Query: 85 ASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFV 127
A + NR + RR + + G + + S R SF+
Sbjct: 496 AKEWRNRRKKRRQREHLEGNNKGERDSFPKSESEDSVKRSSFL 538
>gi|126362949 sodium channel, voltage-gated, type III, alpha isoform
1 [Homo sapiens]
Length = 2000
Score = 33.5 bits (75), Expect = 0.11
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 5/103 (4%)
Query: 30 EEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEA-----GDLSTALERFGQAICLLPER 84
EEAE++E E ++ Q + +Q +A + AA G L LE +A L +
Sbjct: 436 EEAEQKEAEFQQMLEQLKKQQEEAQAVAAASAASRDFSGIGGLGELLESSSEASKLSSKS 495
Query: 85 ASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFV 127
A + NR + RR + + G + + S R SF+
Sbjct: 496 AKEWRNRRKKRRQREHLEGNNKGERDSFPKSESEDSVKRSSFL 538
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 32.7 bits (73), Expect = 0.19
Identities = 20/96 (20%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 27 DLGEEAEKEEREEDEVFPQA-QLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERA 85
++ + KE P A +E+++ L+ +G + G+ A+E++ +++ +
Sbjct: 168 EMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLES 227
Query: 86 SAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRA 121
+ Y+NRA + A++D A++L G +A
Sbjct: 228 ATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKA 263
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 32.3 bits (72), Expect = 0.25
Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 16/122 (13%)
Query: 28 LGEEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASA 87
L E+ +K+E E + Q+++E +AL +Q + + +L +E + I ERAS
Sbjct: 1082 LDEKLKKKEFEISNL--QSKIEDEQALGIQ--LQKKIKELQARIEELEEEI--EAERAS- 1134
Query: 88 YNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRDFE 147
RA+A + + D++ LE++ +E +GG A Q + + + RRD E
Sbjct: 1135 ---RAKAEKQRSDLSRELEEISERLEEAGGATSA------QIEMNKKREAEFQKMRRDLE 1185
Query: 148 RA 149
A
Sbjct: 1186 EA 1187
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 32.3 bits (72), Expect = 0.25
Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 16/122 (13%)
Query: 28 LGEEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASA 87
L E+ +K+E E + Q+++E +AL +Q + + +L +E + I ERAS
Sbjct: 1082 LDEKLKKKEFEISNL--QSKIEDEQALGIQ--LQKKIKELQARIEELEEEI--EAERAS- 1134
Query: 88 YNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRDFE 147
RA+A + + D++ LE++ +E +GG A Q + + + RRD E
Sbjct: 1135 ---RAKAEKQRSDLSRELEEISERLEEAGGATSA------QIEMNKKREAEFQKMRRDLE 1185
Query: 148 RA 149
A
Sbjct: 1186 EA 1187
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 32.3 bits (72), Expect = 0.25
Identities = 26/90 (28%), Positives = 48/90 (53%), Gaps = 10/90 (11%)
Query: 28 LGEEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASA 87
L E+ +K+E E + + + EQ+ A++LQ + +L +E + I ERAS
Sbjct: 1080 LNEKLKKKEFEMSNLQGKIEDEQALAIQLQ----KKIKELQARIEELEEEI--EAERAS- 1132
Query: 88 YNNRAQARRLQGDVAGALEDLERAVELSGG 117
RA+A + + D++ LE++ +E +GG
Sbjct: 1133 ---RAKAEKQRSDLSRELEEISERLEEAGG 1159
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 32.0 bits (71), Expect = 0.33
Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 16/122 (13%)
Query: 28 LGEEAEKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASA 87
L E+ +K+E E + Q+++E +AL +Q + + +L +E + I ERAS
Sbjct: 1080 LDEKLKKKEFEMSGL--QSKIEDEQALGMQ--LQKKIKELQARIEELEEEI--EAERAS- 1132
Query: 88 YNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRDDDARRDFE 147
RA+A + + D++ LE++ +E +GG A Q + + + RRD E
Sbjct: 1133 ---RAKAEKQRSDLSRELEEISERLEEAGGATSA------QIEMNKKREAEFQKMRRDLE 1183
Query: 148 RA 149
A
Sbjct: 1184 EA 1185
>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
Length = 775
Score = 32.0 bits (71), Expect = 0.33
Identities = 47/154 (30%), Positives = 63/154 (40%), Gaps = 26/154 (16%)
Query: 21 GDIVGLDLGEEA-EKEEREEDEVFPQAQLEQSKALELQGVMAAEAGDLSTALERFGQAIC 79
G + ++ EEA E+EE +E+E P QL LQ +AA L G C
Sbjct: 41 GGVGAVEPPEEADEEEEADEEEETPPRQL-------LQRYLAAAGEQLEP-----GLCYC 88
Query: 80 LLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQRGLLARLQGRD 139
LP + + A R + G+ R E++ GRA R + G L GRD
Sbjct: 89 PLPAGQAGAPPPSAAPRSDACLLGS-GSKHRGAEVAD--GRAPRHEGMTNGDSGFLPGRD 145
Query: 140 DDARRDFERA---ARLGSPFARRQLVLLNPYAAL 170
RD E A AR G +RR+ PY L
Sbjct: 146 ---CRDLEEARGLARAGGRESRRR----RPYGRL 172
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 32.0 bits (71), Expect = 0.33
Identities = 21/61 (34%), Positives = 31/61 (50%)
Query: 53 ALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAV 112
AL+ +G A G+ TA+ R+ + + L + Y NRAQA D AL D E A+
Sbjct: 108 ALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWAL 167
Query: 113 E 113
+
Sbjct: 168 K 168
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,559,118
Number of Sequences: 37866
Number of extensions: 266065
Number of successful extensions: 2414
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 2289
Number of HSP's gapped (non-prelim): 172
length of query: 189
length of database: 18,247,518
effective HSP length: 96
effective length of query: 93
effective length of database: 14,612,382
effective search space: 1358951526
effective search space used: 1358951526
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.