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Search of human proteins with 122937261
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937261 coiled-coil domain containing 85A [Homo sapiens]
(553 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937261 coiled-coil domain containing 85A [Homo sapiens] 1139 0.0
gi|223671856 coiled-coil domain containing 85C [Homo sapiens] 254 1e-67
gi|46094079 hepatitis delta antigen-interacting protein A [Homo ... 165 1e-40
gi|57864582 hornerin [Homo sapiens] 53 6e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 51 3e-06
gi|14249338 BUD13 homolog isoform 1 [Homo sapiens] 50 4e-06
gi|47578107 delangin isoform B [Homo sapiens] 50 5e-06
gi|47578105 delangin isoform A [Homo sapiens] 50 5e-06
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol... 50 7e-06
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo... 50 7e-06
gi|41281612 zinc finger protein 828 [Homo sapiens] 50 7e-06
gi|188536004 zinc finger protein 469 [Homo sapiens] 49 9e-06
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s... 49 1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 49 2e-05
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 48 2e-05
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 48 2e-05
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 48 2e-05
gi|169204930 PREDICTED: hypothetical protein [Homo sapiens] 47 3e-05
gi|239750393 PREDICTED: hypothetical protein [Homo sapiens] 47 3e-05
gi|239744694 PREDICTED: hypothetical protein [Homo sapiens] 47 3e-05
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 47 3e-05
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 47 5e-05
gi|9945320 cyclin L1 [Homo sapiens] 47 6e-05
gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo sa... 47 6e-05
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 46 8e-05
gi|229577273 BUD13 homolog isoform 2 [Homo sapiens] 46 1e-04
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens] 46 1e-04
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 45 2e-04
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 44 4e-04
gi|217330641 IWS1 homolog [Homo sapiens] 44 5e-04
>gi|122937261 coiled-coil domain containing 85A [Homo sapiens]
Length = 553
Score = 1139 bits (2947), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 1 MSKAAGGAAAAAAAAESCSPAPAGSSAAPPAPVEDLSKVSDEELLQWSKEELIRSLRRAE 60
MSKAAGGAAAAAAAAESCSPAPAGSSAAPPAPVEDLSKVSDEELLQWSKEELIRSLRRAE
Sbjct: 1 MSKAAGGAAAAAAAAESCSPAPAGSSAAPPAPVEDLSKVSDEELLQWSKEELIRSLRRAE 60
Query: 61 AEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGK 120
AEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGK
Sbjct: 61 AEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGK 120
Query: 121 RVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGC 180
RVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGC
Sbjct: 121 RVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGC 180
Query: 181 AGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKP 240
AGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKP
Sbjct: 181 AGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKP 240
Query: 241 RSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGS 300
RSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGS
Sbjct: 241 RSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGS 300
Query: 301 SPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPE 360
SPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPE
Sbjct: 301 SPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPE 360
Query: 361 HLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYV 420
HLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYV
Sbjct: 361 HLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYV 420
Query: 421 RQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCL 480
RQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCL
Sbjct: 421 RQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCL 480
Query: 481 PTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLKVVWRKLGDAAGSCPGI 540
PTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLKVVWRKLGDAAGSCPGI
Sbjct: 481 PTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLKVVWRKLGDAAGSCPGI 540
Query: 541 RQHLSGNQYKGPM 553
RQHLSGNQYKGPM
Sbjct: 541 RQHLSGNQYKGPM 553
>gi|223671856 coiled-coil domain containing 85C [Homo sapiens]
Length = 419
Score = 254 bits (650), Expect = 1e-67
Identities = 145/265 (54%), Positives = 173/265 (65%), Gaps = 19/265 (7%)
Query: 23 AGSSAAPPAPVEDLSKVSDEELLQWSKEELIRSLRRAEAEKVSAMLDHSNLIREVNRRLQ 82
A +A A E+LS+V DEELL+WSKEEL R LRRAE EKV ML+H L+R+VNRRLQ
Sbjct: 2 AKPAATAAAASEELSQVPDEELLRWSKEELARRLRRAEGEKVGLMLEHGGLMRDVNRRLQ 61
Query: 83 LHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVA 142
HL EIRGLKD+NQ+LQ+DNQELR+LCCFLDDDRQKG++++REWQR GR+ AG + EVA
Sbjct: 62 QHLLEIRGLKDVNQRLQDDNQELRELCCFLDDDRQKGRKLAREWQRFGRHAAGAVWHEVA 121
Query: 143 LYLQKLKDLEVKQEEVVKENMELKELCVLLDEEK--------------GAGCAGSRCSID 188
QKL++LE +QE +++EN+ELKEL +LLDEE+ G G AGSR SID
Sbjct: 122 RSQQKLRELEARQEALLRENLELKELVLLLDEERAALAATGAASGGGGGGGGAGSRSSID 181
Query: 189 SQASLCQLTASTAP--YVRDVGDGSSTSSTGSTDSPDHHKHHASSGSP--EHLQKPRSEG 244
SQASL + AP RDVGDGSSTSS GS SPDHH H P H G
Sbjct: 182 SQASLSGPLSGGAPGAGARDVGDGSSTSSAGSGGSPDHHHHVPPPLLPPGPHKAPDGKAG 241
Query: 245 SPEHS-KHRSASPEHPQKPRACGTP 268
+ S SA P H P P
Sbjct: 242 ATRRSLDDLSAPPHHRSIPNGLHDP 266
Score = 87.0 bits (214), Expect = 4e-17
Identities = 69/229 (30%), Positives = 99/229 (43%), Gaps = 65/229 (28%)
Query: 367 GGSPDHKHG--------GGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLS 418
GGSPDH H G G G +R R PHHR++ +G+++ + +
Sbjct: 214 GGSPDHHHHVPPPLLPPGPHKAPDGKAGATR----RSLDDLSAPPHHRSIPNGLHDPSST 269
Query: 419 YVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGR 478
Y+RQLE++VR LE + + QA + + KG+
Sbjct: 270 YIRQLESKVRLLEGDKLLAQQAGSGEFR-------TLRKGFSPYHSESQ----------- 311
Query: 479 CLPTLPGSFRLSSGADGSNSSPNSAASFS-GHATPSQQPEPVVHSLKV------------ 525
L +LP S++ S + +P + S G++ Q+PE VVH++KV
Sbjct: 312 -LASLPPSYQDSLQNGPACPAPELPSPPSAGYSPAGQKPEAVVHAMKVLEVHENLDRQLQ 370
Query: 526 ---------------------VWRKLGDAAGSCPGIRQHLSGNQYKGPM 553
VWRKLGDAA S P IRQHLSGNQ+KGP+
Sbjct: 371 DSCEEDLSEKEKAIVREMCNVVWRKLGDAASSKPSIRQHLSGNQFKGPL 419
>gi|46094079 hepatitis delta antigen-interacting protein A [Homo
sapiens]
Length = 202
Score = 165 bits (417), Expect = 1e-40
Identities = 90/193 (46%), Positives = 129/193 (66%), Gaps = 13/193 (6%)
Query: 36 LSKVSDEELLQWSKEELIRSLRRAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDIN 95
L +++DEE+ KEEL+R LRR EA +++A++ L++EVNR+LQ HLGEIR LK +N
Sbjct: 8 LEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLN 67
Query: 96 QKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQ 155
++LQ +N+ELRDLCCFLD +RQ+G+R +R+WQ G + + +++ QKL +LE +Q
Sbjct: 68 RRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQ 127
Query: 156 EEVVKENMELKELCVLLDEEKG-----AGCAGSRCSIDSQASLCQLTASTAPYVRDVGDG 210
EE+++EN+ LKELC+ L EE G +G GS + +L P RD+GDG
Sbjct: 128 EELLRENLALKELCLALGEEWGPRGGPSGAGGSGAGPAPELAL----PPCGP--RDLGDG 181
Query: 211 SSTSSTGSTDSPD 223
S SSTGS SPD
Sbjct: 182 S--SSTGSVGSPD 192
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 53.1 bits (126), Expect = 6e-07
Identities = 62/218 (28%), Positives = 81/218 (37%), Gaps = 30/218 (13%)
Query: 210 GSSTSSTGSTDSPDHHKHHA--SSGSPEHLQKP-RSEGSPEH---SKHRSASPEHPQKPR 263
G S +G + S D H + SSG +H +S G +H S H S +H +
Sbjct: 206 GQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSG 265
Query: 264 ACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSG 323
+R ++ G S + + GS + H GS P HV GS SG
Sbjct: 266 QSSRGERHRSSSGSSSSYGQH-GSGSRQSLGHGRQGSGSRQSPSHVRHGS-------GSG 317
Query: 324 SSPEHARH-SGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPD----HKHGGGS 378
S H +H SG S + + H GS QH GS KHG GS
Sbjct: 318 HSSSHGQHGSGSSYSYSRGHYESGS---------GQTSGFGQHESGSGQSSGYSKHGSGS 368
Query: 379 GGSGGSG-GGSREGTLRRQAQEDGSPHHRNVYSGMNES 415
G S G GS G Q S + Y G +ES
Sbjct: 369 GHSSSQGQHGSTSGQASSSGQHGSSSRQSSSY-GQHES 405
Score = 52.0 bits (123), Expect = 1e-06
Identities = 92/383 (24%), Positives = 127/383 (33%), Gaps = 51/383 (13%)
Query: 208 GDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASP------EHPQK 261
G G SS+G + S H + S RS S +H S+S +H
Sbjct: 1166 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSG 1225
Query: 262 PRACGTPDRPKALKGPSPE---HHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQ 318
R R + G SP H L S Q G S P SG F
Sbjct: 1226 SRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 1285
Query: 319 KHRSGS--SPEHARHSGGSPEHLQK-----------------HALGGSLEHLPRARGTSP 359
+H SGS S +++H GS + + G S + R G+S
Sbjct: 1286 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQ 1345
Query: 360 EHLKQHYGG----SPDH-KHGGGSG----------GSGGSGGGSREGTLRRQAQEDGSPH 404
+G SP +HG GSG GSG S R G+ Q G H
Sbjct: 1346 SSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS--GSGQSSGFGH 1403
Query: 405 HRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRAR 464
H + S S + E+ Q+S+ R + SS+ GS +R
Sbjct: 1404 HES--SSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSR 1461
Query: 465 RVLQWWQGCRGIGRCLPTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLK 524
+ L Q G G+ G SG S S S + +S P + HS
Sbjct: 1462 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSS--HSSG 1519
Query: 525 VVWRKLGDAAGSCPGIRQHLSGN 547
+ R+ +G G QH S +
Sbjct: 1520 LGHRE--SRSGQSSGYGQHGSSS 1540
Score = 46.6 bits (109), Expect = 6e-05
Identities = 87/379 (22%), Positives = 128/379 (33%), Gaps = 55/379 (14%)
Query: 177 GAGCAGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTS------STGSTDSPDHHKHHAS 230
G G GSR S+ + ++ ++ G GS S +GS SP H +H +
Sbjct: 256 GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG 315
Query: 231 SGSPEHLQKPRSEGSPEHSKHRSASPEHPQK---PRACGTPDRPKALKGPSPEHHKPLCK 287
SG + S S +S+ S G+ K S H
Sbjct: 316 SGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGH----- 370
Query: 288 GSPEQQRHPHPGSSPETLPKHVLS-------GSPEHFQKHRSGSSPEHARHSGGSPEHLQ 340
S Q +H + +H S G E +H SG +H+ SG SP H Q
Sbjct: 371 -SSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRG-QHSSGSGQSPGHGQ 428
Query: 341 KHA--------------LGGSLEHLPRARGTSPEHLKQHYGGSPDH-----KHGGGSGGS 381
+ + G S P G+ H+ S +H +HG GSG S
Sbjct: 429 RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHS 488
Query: 382 GGSG-GGSREGTL---RRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRML 437
G G GSR G RQ GS + + +L + R +
Sbjct: 489 SGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRH--------GSGSGQS 540
Query: 438 PQASQNRRQPPTRNSSNM-EKGWGSRARRVLQWWQGCRGIGRCLPTLPGSFRLSSGADGS 496
P S+ R + +R SS+ G+GS ++ G L SSG
Sbjct: 541 PSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQH 600
Query: 497 NSSPNSAASFSGHATPSQQ 515
SS +++ H + S Q
Sbjct: 601 GSSSGHSSTHGQHGSTSGQ 619
Score = 46.2 bits (108), Expect = 8e-05
Identities = 94/392 (23%), Positives = 130/392 (33%), Gaps = 69/392 (17%)
Query: 208 GDGSSTSSTGSTDSPDHHKHHA--SSGSPEHL----QKPRSEGSPEHSKHRSASPEHPQK 261
G G SS+G + S H + SSG +H Q R E S+ S +H
Sbjct: 1636 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSG 1695
Query: 262 PRACGTPDRPKALKGPSPE---HHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQ 318
R R + G SP H L S Q G S P SG F
Sbjct: 1696 SRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 1755
Query: 319 KHRSGS--SPEHARHSGGSP------EHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSP 370
+H SGS S +++H GS +H + + + G S H QH GS
Sbjct: 1756 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH-GQHGSGSS 1814
Query: 371 DH-----------------KHGGGSG----------GSG--------GSGGGSREGTLRR 395
+HG GSG GSG GSG G G
Sbjct: 1815 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1874
Query: 396 QAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNM 455
++ S + SG S+ SY E+ Q+S+ + + SS+
Sbjct: 1875 ESSSWQSSGYTQHGSGSGHSS-SY-----------EQHGSRSGQSSRGEQHGSSSGSSSS 1922
Query: 456 EKGWGSRARRVLQWWQGCRGIGRCLPTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQ 515
GS +R+ L Q G G+ G SG S S + +S P +
Sbjct: 1923 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYES 1982
Query: 516 PEPVVHSLKVVWRKLGDAAGSCPGIRQHLSGN 547
HS + R+ +G G QH S +
Sbjct: 1983 GSG--HSSGLGHRE--SRSGQSSGYGQHGSSS 2010
Score = 45.4 bits (106), Expect = 1e-04
Identities = 85/384 (22%), Positives = 124/384 (32%), Gaps = 61/384 (15%)
Query: 182 GSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSS------TGSTDSPDHHKHHASSGSPE 235
GSR S++ ++ + G GS SS +GS SP +H +SSG
Sbjct: 730 GSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSG--- 786
Query: 236 HLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPD---RPKALKGPSPEHHKPLCKGSPEQ 292
S +H S S G + ++ G H Q
Sbjct: 787 -----HSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841
Query: 293 QRHPHPGSSPETLPKH-VLSGSPEHFQKHRSGSSP-----EHARHSGGSPEHLQKHALGG 346
RH + +H SG + +H S S H SG SP H Q+ +
Sbjct: 842 GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGS--- 898
Query: 347 SLEHLPRARGTSPEHLKQHYGG---SPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSP 403
G SP + + G S +HG GSG S G G S G Q
Sbjct: 899 -------GSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGS 951
Query: 404 HHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRA 463
H + Y E+ Q+S++ + + SS+ GS +
Sbjct: 952 GHSSSY---------------------EQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGS 990
Query: 464 RRVLQWWQGCRGIGRCLPTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSL 523
R+ L Q G G+ G SG S S + +S P + HS
Sbjct: 991 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSG--HSS 1048
Query: 524 KVVWRKLGDAAGSCPGIRQHLSGN 547
+ R+ +G G QH S +
Sbjct: 1049 GLGHRE--SRSGQSSGYGQHGSSS 1070
Score = 44.3 bits (103), Expect = 3e-04
Identities = 103/435 (23%), Positives = 133/435 (30%), Gaps = 89/435 (20%)
Query: 175 EKGAGCA---GSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASS 231
E G+G G S Q+S S + + G STS S+ SS
Sbjct: 339 ESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSS 398
Query: 232 GSPEHLQKPR-SEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHH-------- 282
+H R S G +HS SP H Q+ G + PS H
Sbjct: 399 SYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSG--------QSPSSGQHGTGFGRSS 450
Query: 283 --KPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPE-HFQKH------------------R 321
P GS H SS E + GS H H
Sbjct: 451 SSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSS 510
Query: 322 SGSSPEHARHSGGSPEHL--QKHALGGSLEHLP-RARGTSPEHLKQHYGGSPDHKHGGGS 378
+GSS + +H GS + L +H G P R R S YG HG GS
Sbjct: 511 AGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYG-----PHGYGS 565
Query: 379 G----------GSGGSGG----GSREGTLRRQAQEDGSPHHRNVYS--GMNESTLSYVRQ 422
G GSG S G SR G Q S H + + G S Q
Sbjct: 566 GRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ 625
Query: 423 LEARVRQLEEENRMLPQASQNRR---------QPPTRNSSNMEKGWGSRARRVLQWWQGC 473
A Q + +SQ+ R Q P+R + G S + Q
Sbjct: 626 HGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSS------SYGQHG 679
Query: 474 RGIGRCLPTLP-GSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLKVVWRKLGD 532
G G P GS S G S ++ +S H + S +RK G
Sbjct: 680 SGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSG--------YRKHGS 731
Query: 533 AAGSCPGIRQHLSGN 547
+G QH S +
Sbjct: 732 RSGQSSRSEQHGSSS 746
Score = 44.3 bits (103), Expect = 3e-04
Identities = 60/235 (25%), Positives = 82/235 (34%), Gaps = 29/235 (12%)
Query: 197 TASTAPYVRDVGDGSST----SSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHR 252
++S PY G SS S +G + H + + S S S H +H
Sbjct: 1021 SSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG 1080
Query: 253 SASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSG 312
S S + +CG + A G S H + GS + + GS P H G
Sbjct: 1081 STSGQSS----SCG---QHGASSGQSSSHGQH-GSGSSQSSGYGRQGSGSGQSPGHGQRG 1132
Query: 313 SPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDH 372
S S SP + RH GS G L + H + G S +
Sbjct: 1133 SG-------SRQSPSYGRHGSGSGRSSSSGQHGSGL-----GESSGFGHHESSSGQSSSY 1180
Query: 373 -KHGGGSGGSGGSG-GGSREGTL---RRQAQEDGSPHHRNVYSGMNESTLSYVRQ 422
+HG GSG S G G GSR G R GS H + + + + RQ
Sbjct: 1181 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 1235
Score = 43.9 bits (102), Expect = 4e-04
Identities = 89/365 (24%), Positives = 124/365 (33%), Gaps = 39/365 (10%)
Query: 214 SSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSAS------PEHPQKPRACGT 267
SSTG + S H +S S Q S SP +H S S +H +
Sbjct: 2268 SSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 2327
Query: 268 PDRPKALKGPSP--EHHKPLCKGSPEQQRHPHPGSSPETLPKH-VLSGSPEHFQKH--RS 322
R + G S HH+ S +H + +H SG ++H S
Sbjct: 2328 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS 2387
Query: 323 GSSPEHARHSGGSPEHL--QKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSG- 379
GSS + +H GS + L +H G P +RG Q SP +G GSG
Sbjct: 2388 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP-SRGRHGSGSGQSSSYSP---YGSGSGW 2443
Query: 380 ---------GSGGSGG----GSREGTLRRQAQEDGSPHHRNVYS--GMNESTLSYVRQLE 424
GSG S G SR G Q S H + + G S Q
Sbjct: 2444 SSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 2503
Query: 425 ARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSR---ARRVLQWWQGCRGIGRCLP 481
A Q + +SQ+ + S G G R +R+ + + G GR
Sbjct: 2504 ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 2563
Query: 482 TLPGSFRL--SSGADGSNSSPNSAASFSGHATPSQQPEPV-VHSLKVVWRKLGDAAGSCP 538
+ L SSG SS ++S+S H + S H + G+ GS
Sbjct: 2564 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSS 2623
Query: 539 GIRQH 543
G H
Sbjct: 2624 GSSSH 2628
Score = 43.1 bits (100), Expect = 7e-04
Identities = 86/349 (24%), Positives = 125/349 (35%), Gaps = 42/349 (12%)
Query: 205 RDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRA 264
+ +G G S +G + SP +H + SG P GS S S P +
Sbjct: 1462 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS-YSPYGSGSGWSS---SRGPYESGSSHS 1517
Query: 265 CGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKH--RS 322
G R ++ G S + + S H GS+ SG +H S
Sbjct: 1518 SGLGHR-ESRSGQSSGYGQH-GSSSGHSSTHGQHGST---------SGQSSSCGQHGASS 1566
Query: 323 GSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGG--SPDH-KHGGGSG 379
G S H +H GS + G G SP H ++ G SP + +HG GSG
Sbjct: 1567 GQSSSHGQHGSGSSQSSGYGRQGS-------GSGQSPGHGQRGSGSRQSPSYGRHGSGSG 1619
Query: 380 GSGGSG-GGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLP 438
S SG GS G + G HH + S S+ S +
Sbjct: 1620 RSSSSGQHGSGLG------ESSGFGHHES--SSGQSSSYSQHGSGSGHSSGYGQHGSRSG 1671
Query: 439 QASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCLPTLPGSFRLSSGADGSNS 498
Q+S+ R + SS+ GS +R+ + G G+ P R SG G +S
Sbjct: 1672 QSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQS----PSRGRHGSGL-GHSS 1726
Query: 499 SPNSAASFSGHATPSQQPEPVVHSLKVVWRKLGDAAGSCPGIRQHLSGN 547
S S SG ++ S+ P V+ + +G QH SG+
Sbjct: 1727 SHGQHGSGSGRSS-SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 1774
Score = 42.4 bits (98), Expect = 0.001
Identities = 57/214 (26%), Positives = 76/214 (35%), Gaps = 27/214 (12%)
Query: 210 GSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPD 269
G +S+G + S H +S S Q S SP H + S S + P R
Sbjct: 2500 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 2559
Query: 270 RPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHA 329
R + S +H G E H SS SG + +H SGS
Sbjct: 2560 RSSS----SGQHGS----GLGESSGFGHHESS---------SGQSSSYSQHGSGSG---- 2598
Query: 330 RHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHK-HGGGSGGSGGSGGGS 388
HS G +H + E + G+S H QH GS HG GSG S
Sbjct: 2599 -HSSGYGQHGSRSGQSSRGERHGSSSGSS-SHYGQHGSGSRQSSGHGRQGSGSGQSPSRG 2656
Query: 389 REGTLRRQAQ---EDGSPHHRNVYSGMNESTLSY 419
R G+ + + GS R+ G ES L +
Sbjct: 2657 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGH 2690
Score = 41.6 bits (96), Expect = 0.002
Identities = 50/184 (27%), Positives = 65/184 (35%), Gaps = 24/184 (13%)
Query: 210 GSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPD 269
G +S+G + S H +S S Q S SP H + S S + P R
Sbjct: 1090 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 1149
Query: 270 RPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHA 329
R + S +H G E H SS SG + +H SGS
Sbjct: 1150 RSSS----SGQHGS----GLGESSGFGHHESS---------SGQSSSYSQHGSGSG---- 1188
Query: 330 RHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHK-HGGGSGGSGGSGGGS 388
HS G +H + E + G+S H QH GS HG GSG S
Sbjct: 1189 -HSSGYGQHGSRSGQSSRGERHGSSSGSS-SHYGQHGSGSRQSSGHGRQGSGSGHSPSRG 1246
Query: 389 REGT 392
R G+
Sbjct: 1247 RHGS 1250
Score = 41.6 bits (96), Expect = 0.002
Identities = 47/183 (25%), Positives = 62/183 (33%), Gaps = 22/183 (12%)
Query: 210 GSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPD 269
G +S+G + S H +S S Q S SP H + S S + P R
Sbjct: 2030 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 2089
Query: 270 RPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHA 329
R S H P G E H SS SG + +H SGS
Sbjct: 2090 RSS-----SSGQHGP---GLGESSGFGHHESS---------SGQSSSYSQHGSGSG---- 2128
Query: 330 RHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSR 389
HS G +H + E + G+S + + G HG GSG S R
Sbjct: 2129 -HSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR 2187
Query: 390 EGT 392
G+
Sbjct: 2188 HGS 2190
Score = 41.6 bits (96), Expect = 0.002
Identities = 60/257 (23%), Positives = 84/257 (32%), Gaps = 52/257 (20%)
Query: 205 RDVGDGSSTSSTGSTDSPDHHKHHASSG-----SP------------------------- 234
+ +G G S +G + SP +H + SG SP
Sbjct: 2402 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLG 2461
Query: 235 -EHLQKPRSEGSPEH---SKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSP 290
+ +S G +H S H S +H + + A G S H + GS
Sbjct: 2462 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH-GSGSS 2520
Query: 291 EQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEH 350
+ + GS P H GS S SP + RH GS G L
Sbjct: 2521 QSSGYGRQGSGSGQSPGHGQRGS-------GSRQSPSYGRHGSGSGRSSSSGQHGSGL-- 2571
Query: 351 LPRARGTSPEHLKQHYGGSPDH-KHGGGSGGSGGSG-GGSREGTL---RRQAQEDGSPHH 405
+ H + G S + +HG GSG S G G GSR G R GS H
Sbjct: 2572 ---GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSH 2628
Query: 406 RNVYSGMNESTLSYVRQ 422
+ + + + RQ
Sbjct: 2629 YGQHGSGSRQSSGHGRQ 2645
Score = 40.4 bits (93), Expect = 0.004
Identities = 79/345 (22%), Positives = 118/345 (34%), Gaps = 34/345 (9%)
Query: 205 RDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRA 264
+ +G G S +G + SP +H + SG P GS S S P +
Sbjct: 1932 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS-YGPYGSGSGWSS---SRGPYESGSGHS 1987
Query: 265 CGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKH--RS 322
G R ++ G S + + S H GS+ SG +H S
Sbjct: 1988 SGLGHR-ESRSGQSSGYGQH-GSSSGHSSTHGQHGSA---------SGQSSSCGQHGASS 2036
Query: 323 GSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSG 382
G S H +H GS + G G SP H ++ G +G GSG
Sbjct: 2037 GQSSSHGQHGSGSSQSSGYGRQGS-------GSGQSPGHGQRGSGSRQSPSYGRHGSGSG 2089
Query: 383 GSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQ 442
S + G + G HH + S S+ S + Q+S+
Sbjct: 2090 RSSSSGQHGP--GLGESSGFGHHES--SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2145
Query: 443 NRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCLPTLPGSFRLSSGADGSNSSPNS 502
R + SS+ GS +R+ + G G P R SG+ G +SS
Sbjct: 2146 GERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHS----PSRGRHGSGS-GHSSSHGQ 2200
Query: 503 AASFSGHATPSQQPEPVVHSLKVVWRKLGDAAGSCPGIRQHLSGN 547
S SG ++ S+ P V+ + +G QH SG+
Sbjct: 2201 HGSGSGRSS-SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 2244
Score = 40.0 bits (92), Expect = 0.006
Identities = 53/228 (23%), Positives = 80/228 (35%), Gaps = 29/228 (12%)
Query: 210 GSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEG--SPEHSKHRSASPE---HPQKPRA 264
G + +GS S + +H + SG ++ S S + +H S S + H Q
Sbjct: 1413 GCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1472
Query: 265 CGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEH-----FQK 319
G + PSP + P+ S + + H ++
Sbjct: 1473 SG--------QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRE 1524
Query: 320 HRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRA-------RGTSPEHLKQHYGGSPDH 372
RSG S + +H G S H H GS + G S H + G S
Sbjct: 1525 SRSGQSSGYGQH-GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 1583
Query: 373 KHGGGSGGSGGSGGGSREGTLRRQAQ---EDGSPHHRNVYSGMNESTL 417
+G GSG S G + G+ RQ+ GS R+ SG + S L
Sbjct: 1584 GYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL 1631
Score = 39.7 bits (91), Expect = 0.007
Identities = 61/227 (26%), Positives = 84/227 (37%), Gaps = 32/227 (14%)
Query: 208 GDGSSTS----STGSTDSPDHHKHHASSGSPEHLQK--PRSEGSPEHSKHRSASPEHPQK 261
G G S+S + S S +H +SSGS + S S H +H S S + P
Sbjct: 2360 GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 2419
Query: 262 PRACGTPDRPKALKGPSPEHHKPLCKGSP-EQQRHPHPGSSPETLPKHVLSGSPEHFQKH 320
R R + G S + P GS R P+ S + S ++
Sbjct: 2420 SRG-----RHGSGSGQSSSY-SPYGSGSGWSSSRGPYESGSGHS--------SGLGHRES 2465
Query: 321 RSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRA-------RGTSPEHLKQHYGGSPDHK 373
RSG S + +H G S H H GS + G S H + G S
Sbjct: 2466 RSGQSSGYGQH-GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG 2524
Query: 374 HGGGSGGSGGSGGGSREGTLRRQAQ---EDGSPHHRNVYSGMNESTL 417
+G GSG S G + G+ RQ+ GS R+ SG + S L
Sbjct: 2525 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL 2571
Score = 38.9 bits (89), Expect = 0.012
Identities = 52/214 (24%), Positives = 74/214 (34%), Gaps = 24/214 (11%)
Query: 214 SSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKA 273
S +G + + H + S S S S H +H S S + P R R +
Sbjct: 962 SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG-----RHGS 1016
Query: 274 LKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHARHSG 333
G S + R P+ S + S ++ RSG S + +H G
Sbjct: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHS--------SGLGHRESRSGQSSGYGQH-G 1067
Query: 334 GSPEHLQKHALGGSLEHLPRA-------RGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGG 386
S H H GS + G S H + G S +G GSG S G
Sbjct: 1068 SSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 1127
Query: 387 GSREGTLRRQAQ---EDGSPHHRNVYSGMNESTL 417
+ G+ RQ+ GS R+ SG + S L
Sbjct: 1128 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL 1161
Score = 37.4 bits (85), Expect = 0.036
Identities = 53/211 (25%), Positives = 74/211 (35%), Gaps = 24/211 (11%)
Query: 214 SSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKA 273
S +G + + H + S S S S H +H S S + P R R +
Sbjct: 1902 SRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG-----RHGS 1956
Query: 274 LKGPSPEHHKPLCKGSP-EQQRHPHPGSSPETLP---KHVLSGSPEHFQKH--RSGSSPE 327
G S + P GS R P+ S + + SG + +H SG S
Sbjct: 1957 GSGQSSSYG-PYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2015
Query: 328 HARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGG 387
H +H S + G S G S H + G S +G GSG S G
Sbjct: 2016 HGQHGSASGQSSSCGQHGAS-------SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH 2068
Query: 388 SREGTLRRQAQEDGSPHHRNVYSGMNESTLS 418
+ G+ RQ SP + SG S+ S
Sbjct: 2069 GQRGSGSRQ-----SPSYGRHGSGSGRSSSS 2094
Score = 37.0 bits (84), Expect = 0.047
Identities = 53/205 (25%), Positives = 75/205 (36%), Gaps = 19/205 (9%)
Query: 208 GDGSSTSSTGSTDSPDHHKHHASSGSPEHLQK--PRSEGSPEHSKHRSASPEHPQK-PRA 264
G G SS+G + + H +H ++SG + S S H +H S S + + +
Sbjct: 596 GYGQHGSSSGHSST--HGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQG 653
Query: 265 CGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHF-QKHRSG 323
G+ P + S H S Q G S P +SG F K SG
Sbjct: 654 SGSGQSPSRGRHGSDFGHS-----SSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSG 708
Query: 324 SSPEHARHSGGSPEH--LQKHALGGSLEHLPRARGTSPEHLKQHYG--GSPDHK---HGG 376
S +++H GS +KH G+S L YG GS H+ HG
Sbjct: 709 QSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSS-SGLSSSYGQHGSGSHQSSGHGR 767
Query: 377 GSGGSGGSGGGSREGTLRRQAQEDG 401
GSG S R G+ + G
Sbjct: 768 QGSGSGHSPSRVRHGSSSGHSSSHG 792
Score = 32.7 bits (73), Expect = 0.89
Identities = 54/220 (24%), Positives = 73/220 (33%), Gaps = 30/220 (13%)
Query: 216 TGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSK-------HRSASPEHPQKPRACGTP 268
+GS D H+H E + R E S HS S + KP
Sbjct: 97 SGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESIS 156
Query: 269 DRPKALKGPSPEHHKPLCKGSP--EQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSP 326
R + S +H+ + S EQ H S GS SG SP
Sbjct: 157 RRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSG------RGQCGS-------GSGQSP 203
Query: 327 EHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSG- 385
+ +H GS + G ++ G S +H S +HG GSG S G G
Sbjct: 204 NYGQHGSGSGQSSSNDTHGSG---SGQSSGFS-QHKSSSGQSSGYSQHGSGSGHSSGYGQ 259
Query: 386 GGSREGTL---RRQAQEDGSPHHRNVYSGMNESTLSYVRQ 422
GSR G R GS + + +L + RQ
Sbjct: 260 HGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQ 299
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 50.8 bits (120), Expect = 3e-06
Identities = 45/157 (28%), Positives = 61/157 (38%), Gaps = 19/157 (12%)
Query: 219 TDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPS 278
T +P + S PR P ++ SP P K R P PK PS
Sbjct: 572 TPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRY---SPSPPPKRRTASPPPPPKRRASPS 628
Query: 279 PEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEH 338
P + + P +QR SSP T + SP KHR GSSP + SP+
Sbjct: 629 PPPKRRVSHSPPPKQR-----SSPVTKRR-----SPSLSSKHRKGSSPSRSTREARSPQP 678
Query: 339 LQKHALGGSLEHLPRARGT--SPEHLKQHYGGSPDHK 373
++H S PRA T SP +++ SP +
Sbjct: 679 NKRH----SPSPRPRAPQTSSSPPPVRRGASSSPQRR 711
Score = 38.5 bits (88), Expect = 0.016
Identities = 44/161 (27%), Positives = 56/161 (34%), Gaps = 38/161 (23%)
Query: 210 GSSTS-STGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTP 268
GSS S ST SP +K H+ S P Q S P + S+SP+ Q P P
Sbjct: 663 GSSPSRSTREARSPQPNKRHSPSPRPRAPQT--SSSPPPVRRGASSSPQRRQSPSPSTRP 720
Query: 269 DR-------PKALK---------------------GPSPEHHKPLCKGSPEQQRHPHPGS 300
R PK +K P P KP SP Q + P
Sbjct: 721 IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNW 780
Query: 301 SPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQK 341
SP K S +P S S P ++ GG + +K
Sbjct: 781 SPAVPVKKAKSPTP-------SPSPPRNSDQEGGGKKKKKK 814
Score = 33.9 bits (76), Expect = 0.40
Identities = 43/188 (22%), Positives = 64/188 (34%), Gaps = 32/188 (17%)
Query: 211 SSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASP-EHPQKPRACGTPD 269
SS+SS+ + SP +S P ++ SP +HR + P P K R TP
Sbjct: 359 SSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQ 418
Query: 270 RPKALK------GPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPE-------- 315
+ + P K E++ P P P K LS S E
Sbjct: 419 QSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR---KVELSESEEDKGGKMAA 475
Query: 316 --------HFQKHRSGSSPEHARHSGGSPE-----HLQKHALGGSLEHLPRARGTSPEHL 362
+++ SS + S E H++ +G H P +R SP
Sbjct: 476 ADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSP-SRSASPSPR 534
Query: 363 KQHYGGSP 370
K+ SP
Sbjct: 535 KRQKETSP 542
Score = 32.0 bits (71), Expect = 1.5
Identities = 32/134 (23%), Positives = 43/134 (32%), Gaps = 19/134 (14%)
Query: 211 SSTSSTGSTDSPDH------HKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRA 264
S + S + SP H H+ + S SP PR R SP PR
Sbjct: 282 SKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPR----------RRPSPRRRTPPRR 331
Query: 265 CGTPDRPKALKGPSPEHHKPLC--KGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRS 322
P R + + P + GS S P+ PK S P ++
Sbjct: 332 MPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRT-SSPPRKTRRLSP 390
Query: 323 GSSPEHARHSGGSP 336
+SP RH P
Sbjct: 391 SASPPRRRHRPSPP 404
Score = 31.2 bits (69), Expect = 2.6
Identities = 59/263 (22%), Positives = 91/263 (34%), Gaps = 43/263 (16%)
Query: 222 PDHHKHHASSGSPEHLQKPR---SEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPS 278
P +H S ++ S S S RS SP P+KP PK P
Sbjct: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP--PKKP--------PKRTSSPP 382
Query: 279 PEHHKPLCKGSPEQQRH-PHPGSSPETLPKHVLSGSPEHFQKHR-SGSSPEHARHSGGSP 336
+ + SP ++RH P P ++P +H S +P+ + R S S R SG
Sbjct: 383 RKTRRLSPSASPPRRRHRPSPPATPPPKTRH--SPTPQQSNRTRKSRVSVSPGRTSGKVT 440
Query: 337 EHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQ 396
+H + + SP + S + GG + S R+ RRQ
Sbjct: 441 KH----------KGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQ--YRRQ 488
Query: 397 AQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQ---------- 446
Q+ S + S S+V+ E R+ +R + + R++
Sbjct: 489 NQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRR 548
Query: 447 ----PPTRNSSNMEKGWGSRARR 465
PPTR + R RR
Sbjct: 549 SPSPPPTRRRRSPSPAPPPRRRR 571
Score = 30.8 bits (68), Expect = 3.4
Identities = 64/269 (23%), Positives = 93/269 (34%), Gaps = 42/269 (15%)
Query: 233 SPEHLQK---------PRSEG-SPEHSKHRSASPEHPQ-------KPRACGTPDRPKALK 275
SPE K PRS S S+ RS SP H + + R+ RP +
Sbjct: 260 SPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRR 319
Query: 276 GPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKH--VLSGSPEHFQKHRSGSSPEHARHSG 333
PSP P + P RH S + LSGS RS S P+
Sbjct: 320 RPSPRRRTP-PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRT 378
Query: 334 GSP----EHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGS- 388
SP L A H P T P K + +P + S G +
Sbjct: 379 SSPPRKTRRLSPSASPPRRRHRPSPPATPPP--KTRHSPTPQQSNRTRKSRVSVSPGRTS 436
Query: 389 -----REGTLRRQAQEDGSPHHRNVYSGMNE-------STLSYVRQLEARVRQLEEENRM 436
+GT +R++ +P R V +E + V+Q RQ ++ +
Sbjct: 437 GKVTKHKGTEKRESPSP-APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD 495
Query: 437 LPQASQNRRQPPTRNSSNMEKGWGSRARR 465
+S + + P R S+++ G R RR
Sbjct: 496 SGSSSSSEDERPKR--SHVKNGEVGRRRR 522
>gi|14249338 BUD13 homolog isoform 1 [Homo sapiens]
Length = 619
Score = 50.4 bits (119), Expect = 4e-06
Identities = 46/159 (28%), Positives = 64/159 (40%), Gaps = 25/159 (15%)
Query: 224 HHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKG------- 276
H +H SP ++ + SP +H + P P++ R TPD P L+G
Sbjct: 118 HFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPS-PRRARH-DTPD-PSPLRGARHDSDT 174
Query: 277 --PSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSG--SSPEHARHS 332
P H P + RH P SP P+H SG+ +H S S P ARH
Sbjct: 175 SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHG 234
Query: 333 GG---SPEHLQKHA-------LGGS-LEHLPRARGTSPE 360
SP + ++ LG S + L RAR SP+
Sbjct: 235 SSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPD 273
Score = 49.3 bits (116), Expect = 9e-06
Identities = 69/290 (23%), Positives = 101/290 (34%), Gaps = 65/290 (22%)
Query: 198 ASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEG-SPEHSKHRSASP 256
+ T+P R D S TS P +H + SP + S G SP +H S P
Sbjct: 172 SDTSPPRRIRHDSSDTSP------PRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDP 225
Query: 257 EHPQKPRACGTPD--RPKALKGPSPEHHKPLCKGSPEQQ----RHPHPGSSPE---TLPK 307
P++ R G+ D P+ + SP+ + S QQ RH P +P +LP+
Sbjct: 226 SPPRRARH-GSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPR 284
Query: 308 HVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYG 367
+PE S + H + SG S K++ E+ P + K H+G
Sbjct: 285 TKSGKAPER----ASSKTSPHWKESGASHLSFPKNS---KYEYDPDISPPRKKQAKSHFG 337
Query: 368 -------------------GSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNV 408
SP HK G S R R + D SP R
Sbjct: 338 DKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQ 397
Query: 409 YSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKG 458
+ ++S LS R R QPP + +++M G
Sbjct: 398 RTKSSDSDLSPPR----------------------RSQPPGKKAAHMYSG 425
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 50.1 bits (118), Expect = 5e-06
Identities = 57/277 (20%), Positives = 101/277 (36%), Gaps = 27/277 (9%)
Query: 188 DSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPE 247
+S+ + C+ ST V + + S T D+ ++ ++ S K + E PE
Sbjct: 655 ESRTTECKQNESTI--VEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPE 712
Query: 248 HSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPK 307
K +S K + G P+ PK PE K +G PE +H H P
Sbjct: 713 TPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPS 772
Query: 308 HVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYG 367
PE KH+ + + R E +L+ P R S + H
Sbjct: 773 --TEKKPE-VSKHKQDTKSDSPRLKSERAE---------ALKQRPDGRSVSESLRRDH-- 818
Query: 368 GSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARV 427
D+K G G + R + S + + +S S +LE +
Sbjct: 819 ---DNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGI-----KSDSSKTDKLERKH 870
Query: 428 RQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRAR 464
R ++R P + + + +P +S +++G +++R
Sbjct: 871 RHESGDSRERPSSGEQKSRP---DSPRVKQGDSNKSR 904
Score = 31.6 bits (70), Expect = 2.0
Identities = 34/125 (27%), Positives = 49/125 (39%), Gaps = 24/125 (19%)
Query: 204 VRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKP- 262
+R++ D + S S +S +HH + GS E H HR +S +
Sbjct: 215 LRNIHD-NKVSGPLSGNSANHHADNPRHGSSEDYL---------HMVHRLSSDDGDSSTM 264
Query: 263 -RACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPH-------PGSSPETLPKHVLSGSP 314
A P L+ P P +G+P+ R P P SSP +P +L SP
Sbjct: 265 RNAASFP-----LRSPQPVCSPAGSEGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSP 319
Query: 315 EHFQK 319
E QK
Sbjct: 320 ERKQK 324
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 50.1 bits (118), Expect = 5e-06
Identities = 57/277 (20%), Positives = 101/277 (36%), Gaps = 27/277 (9%)
Query: 188 DSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPE 247
+S+ + C+ ST V + + S T D+ ++ ++ S K + E PE
Sbjct: 655 ESRTTECKQNESTI--VEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPE 712
Query: 248 HSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPK 307
K +S K + G P+ PK PE K +G PE +H H P
Sbjct: 713 TPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPS 772
Query: 308 HVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYG 367
PE KH+ + + R E +L+ P R S + H
Sbjct: 773 --TEKKPE-VSKHKQDTKSDSPRLKSERAE---------ALKQRPDGRSVSESLRRDH-- 818
Query: 368 GSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARV 427
D+K G G + R + S + + +S S +LE +
Sbjct: 819 ---DNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGI-----KSDSSKTDKLERKH 870
Query: 428 RQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRAR 464
R ++R P + + + +P +S +++G +++R
Sbjct: 871 RHESGDSRERPSSGEQKSRP---DSPRVKQGDSNKSR 904
Score = 31.6 bits (70), Expect = 2.0
Identities = 34/125 (27%), Positives = 49/125 (39%), Gaps = 24/125 (19%)
Query: 204 VRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKP- 262
+R++ D + S S +S +HH + GS E H HR +S +
Sbjct: 215 LRNIHD-NKVSGPLSGNSANHHADNPRHGSSEDYL---------HMVHRLSSDDGDSSTM 264
Query: 263 -RACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPH-------PGSSPETLPKHVLSGSP 314
A P L+ P P +G+P+ R P P SSP +P +L SP
Sbjct: 265 RNAASFP-----LRSPQPVCSPAGSEGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSP 319
Query: 315 EHFQK 319
E QK
Sbjct: 320 ERKQK 324
>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
isoform b [Homo sapiens]
Length = 373
Score = 49.7 bits (117), Expect = 7e-06
Identities = 68/327 (20%), Positives = 114/327 (34%), Gaps = 32/327 (9%)
Query: 143 LYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGCAGSRCSIDSQASLCQLTASTAP 202
L ++ + D ++ + EV KE +E + + G AG S ++ C +
Sbjct: 17 LAMEYVNDFDLMKFEVKKEPVETDRII----SQCGRLIAGGSLSSTPMSTPCSSVPPSPS 72
Query: 203 YVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKP 262
+ + + +GS ++ +G P+ L SPE + S H +
Sbjct: 73 F------SAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQG 126
Query: 263 RACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRS 322
G + L + GS E+ S SG+ H+ H
Sbjct: 127 GFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHH 186
Query: 323 GSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSG 382
++ H + G+P A G + A G GG P GGG GG G
Sbjct: 187 HAAGHHHHPTAGAPG-----AAGSAAASAGGAGGAG--------GGGPASAGGGGGGGGG 233
Query: 383 GSGGGSREGTLRRQAQEDGSPHHRNVYSGMN-ESTLSYVRQLEARVRQLEEENRMLPQAS 441
G GGG+ A G+ H + G++ + S + + VR+L + R + +
Sbjct: 234 GGGGGA--------AGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEE 285
Query: 442 QNRRQPPTRNSSNMEKGWGSRARRVLQ 468
R + R N R +RV Q
Sbjct: 286 VIRLKQKRRTLKNRGYAQSCRFKRVQQ 312
>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
isoform a [Homo sapiens]
Length = 403
Score = 49.7 bits (117), Expect = 7e-06
Identities = 68/327 (20%), Positives = 114/327 (34%), Gaps = 32/327 (9%)
Query: 143 LYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGCAGSRCSIDSQASLCQLTASTAP 202
L ++ + D ++ + EV KE +E + + G AG S ++ C +
Sbjct: 17 LAMEYVNDFDLMKFEVKKEPVETDRII----SQCGRLIAGGSLSSTPMSTPCSSVPPSPS 72
Query: 203 YVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKP 262
+ + + +GS ++ +G P+ L SPE + S H +
Sbjct: 73 F------SAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQG 126
Query: 263 RACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRS 322
G + L + GS E+ S SG+ H+ H
Sbjct: 127 GFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHH 186
Query: 323 GSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSG 382
++ H + G+P A G + A G GG P GGG GG G
Sbjct: 187 HAAGHHHHPTAGAPG-----AAGSAAASAGGAGGAG--------GGGPASAGGGGGGGGG 233
Query: 383 GSGGGSREGTLRRQAQEDGSPHHRNVYSGMN-ESTLSYVRQLEARVRQLEEENRMLPQAS 441
G GGG+ A G+ H + G++ + S + + VR+L + R + +
Sbjct: 234 GGGGGA--------AGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEE 285
Query: 442 QNRRQPPTRNSSNMEKGWGSRARRVLQ 468
R + R N R +RV Q
Sbjct: 286 VIRLKQKRRTLKNRGYAQSCRFKRVQQ 312
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 49.7 bits (117), Expect = 7e-06
Identities = 57/190 (30%), Positives = 71/190 (37%), Gaps = 35/190 (18%)
Query: 213 TSSTGSTDSPDHHKHHASSGSPEHL-------QKPRSEGSPEHSKHRSASPEHPQKPRAC 265
T S P+H K +S P+ + QK S SPE K +P PQKP +
Sbjct: 103 TDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSV 162
Query: 266 GTPDRPKALKGPSPEHHKPLCKGSPE--------QQRHPHPGSSPETLPKHVLSGSPEHF 317
+P+ L PSPE KP SPE + + P SPE P+ SPE
Sbjct: 163 VSPELQTPL--PSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPE--PQKPAPVSPESV 218
Query: 318 QKHRSGSSPEHARH--------SGGSPEHLQKHAL--------GGSLEHLPRARGTSPEH 361
+ S P+ H S SPE A S E AR TSPE
Sbjct: 219 KATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEP 278
Query: 362 LKQHYGGSPD 371
K SP+
Sbjct: 279 RKPSPSESPE 288
Score = 36.2 bits (82), Expect = 0.081
Identities = 43/130 (33%), Positives = 49/130 (37%), Gaps = 24/130 (18%)
Query: 242 SEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSS 301
S SP K ASPE + G P+ K SPEH K + SPE R P P S
Sbjct: 373 SSVSPSSWKSPPASPESWKS----GPPELRKTAPTLSPEHWKAVPPVSPE-LRKPGPPLS 427
Query: 302 PETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEH 361
PE +GSPE R GSP+ + L A PE
Sbjct: 428 PEIRSP---AGSPE-------------LRKPSGSPDLWK---LSPDQRKTSPASLDFPES 468
Query: 362 LKQHYGGSPD 371
K GGSPD
Sbjct: 469 QKSSRGGSPD 478
Score = 34.7 bits (78), Expect = 0.23
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 16/104 (15%)
Query: 212 STSSTGSTDSPDHHKHHASSGSPEHLQKPRSE--------------GSPEHSKH-RSASP 256
S +T S P H + P P S SPE K R+ SP
Sbjct: 217 SVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSP 276
Query: 257 EHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGS 300
E P+KP +P+ K SPE +P SP + PGS
Sbjct: 277 E-PRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGS 319
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 49.3 bits (116), Expect = 9e-06
Identities = 66/249 (26%), Positives = 95/249 (38%), Gaps = 38/249 (15%)
Query: 211 SSTSSTGSTDSPDHHK---HHASSGSPEHLQ--KPRSEG------SPEHSKHRSASPEHP 259
SST+S +DSP H+ H G P Q K RS G S E+ + + +P P
Sbjct: 2384 SSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGP 2443
Query: 260 QKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGS----SPETLPKH------V 309
C R GP HK ++ PHPG+ SP LP
Sbjct: 2444 VTCEVCAASFR----SGPGLSRHKA-------RKHRPHPGAPAEPSPAALPAQQPLEPLA 2492
Query: 310 LSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGS 369
P + HR S E HS G P H+ + + + RA G SP + H
Sbjct: 2493 QKCQPPRKKSHRV-SGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPG-SPHSQQLHPPSP 2550
Query: 370 PDHKHGGGSGGSGGSGGGSREGTLR-RQAQEDGSPHHR---NVYSGMNESTLSYVRQLEA 425
+H+ + S +RE L +QA++ R V S + S ++ +
Sbjct: 2551 TEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKL 2610
Query: 426 RVRQLEEEN 434
R R+L EE+
Sbjct: 2611 RGRRLREES 2619
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/161 (27%), Positives = 59/161 (36%), Gaps = 20/161 (12%)
Query: 221 SPDHHKHHASSGSPEHLQKPRSEGSP-----EHSKHRSASPEHPQKPRACGTPDRPKALK 275
+P HH+ S+G ++ GSP + + + SP KPRA TP P
Sbjct: 3207 APKHHRGKRSAG--------KAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAA 3258
Query: 276 GPSPEHHKPLC-KGSPEQQR-HPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHARHSG 333
P L GSP R P P P + +L +P H H
Sbjct: 3259 TPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCGKRF 3318
Query: 334 GSPEHLQKHALGGSLEHL---PRARGTSPEH--LKQHYGGS 369
P LQ+H S + + PR PEH L H GG+
Sbjct: 3319 PKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGA 3359
Score = 35.8 bits (81), Expect = 0.11
Identities = 29/120 (24%), Positives = 44/120 (36%), Gaps = 15/120 (12%)
Query: 198 ASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSK------- 250
A++ P V + +TG + +P + A G P P+S G+P H+
Sbjct: 2240 ATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPG--PDPQSRGAPPHTNPDRMPRG 2297
Query: 251 HRSASPE------HPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPET 304
H S SP H + P P L+G P+ L + P +PET
Sbjct: 2298 HSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPET 2357
Score = 30.0 bits (66), Expect = 5.8
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 241 RSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPG 299
RSE + SA + P+ PR TP R K +KP + P +QR PG
Sbjct: 3799 RSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKP--RPPPSEQRKAEPG 3855
>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
sapiens]
Length = 688
Score = 48.9 bits (115), Expect = 1e-05
Identities = 66/276 (23%), Positives = 102/276 (36%), Gaps = 36/276 (13%)
Query: 212 STSSTGSTDSPDHHKHHASSGSPEHLQKPRSE-----GSPEHSKHRSASPEH-------- 258
+T+ T S+ H K SS S H Q+ S+ +P H K S
Sbjct: 393 TTNGTSSSKGTSHSKGQRSSSSTYHRQRRHSDFCGPSPAPLHPKRSPTSTGEAELKEERL 452
Query: 259 PQKPRACGTPDR-PKALKGPSP---EHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSP 314
P + +C T + L SP H P PE+++ S+P LP +++
Sbjct: 453 PGRKASCSTAGSGSRGLPPSSPMVSSAHNPNKAEIPERRKDST--STPNNLPPSMMTRRN 510
Query: 315 EHFQKHRSGSS-----PEHARHSGGSPE----HLQKHALGG-SLEHLPRARGTSPEHLKQ 364
+ R G+ P +S G+P H+L S E ARG++
Sbjct: 511 TYVCTERPGAERPSLLPNGKENSSGTPRVPPASPSSHSLAPPSGERSRLARGSTIR--ST 568
Query: 365 HYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLE 424
+GG + GG GG G G TL +A + R + + T R++
Sbjct: 569 FHGGQVRDRRAGGGGGGGVQNGPPASPTLAHEAAPLPAGRPRPTTNLFTKLTSKLTRRVT 628
Query: 425 ARVRQLEEENR-----MLPQASQNRRQPPTRNSSNM 455
+ + NR LPQ S+ R Q R S ++
Sbjct: 629 LDPSKRQNSNRCVSGASLPQGSKIRSQTNLRESGDL 664
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 48.5 bits (114), Expect = 2e-05
Identities = 71/295 (24%), Positives = 101/295 (34%), Gaps = 61/295 (20%)
Query: 198 ASTAPYVRD-VGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASP 256
+ ++P +RD G S S +GS+ S G E P + P+ + RS SP
Sbjct: 1441 SGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSP 1500
Query: 257 EHPQKPRACGTPDRPKALKGPSPEH----HKPL---CKGSPEQQRHPHPGSSP------E 303
P+ C TP R ++ S + PL + Q+ P +SP +
Sbjct: 1501 SSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESD 1560
Query: 304 TLPKHVLSGSPEHFQKHRSGSSPE---------HARHSGGSPEHLQK-----HALGGSLE 349
+ P Q+ RSGSSPE SG SPE K A GS +
Sbjct: 1561 SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGS-D 1619
Query: 350 HLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVY 409
P + +P L + + G S G G S GS + + SP H
Sbjct: 1620 SSPEPKAPAPRALPRR------SRSGSSSKGRGPSPEGS--------SSTESSPEH---- 1661
Query: 410 SGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRAR 464
+ R +R P+ R PP R SS +AR
Sbjct: 1662 --------------PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKAR 1702
Score = 45.1 bits (105), Expect = 2e-04
Identities = 56/231 (24%), Positives = 94/231 (40%), Gaps = 22/231 (9%)
Query: 226 KHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPL 285
+H S SP + +S P S RS+SP+ K +A +P + SP +
Sbjct: 888 RHSCSGSSPPRV---KSSTPPRQSPSRSSSPQ--PKVKAIISPRQRSHSGSSSPSPSRVT 942
Query: 286 CKGSPEQQRHPHPGSSPET--LPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQK-- 341
+ +P + R P S+ E+ LP++ SGS K + + P + SP K
Sbjct: 943 SRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ 1002
Query: 342 ----HALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQA 397
+L GS P+ + S + L Q GS G S G +L+ +
Sbjct: 1003 TPPGPSLSGSKSPCPQEK--SKDSLVQSCPGSLSLCAGVKSSTPPGESYFG-VSSLQLKG 1059
Query: 398 QEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPP 448
Q SP HR ++++ VRQ + L+ +++ P+ ++R P
Sbjct: 1060 QSQTSPDHR------SDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSP 1104
Score = 41.6 bits (96), Expect = 0.002
Identities = 50/188 (26%), Positives = 67/188 (35%), Gaps = 30/188 (15%)
Query: 211 SSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDR 270
+S + S SP+ K SS L PRS+ S RS S P + TP R
Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR 795
Query: 271 --------PKALKGPSPEHHKPLCKGSPEQQ-----RHPHPGSSPETLPKHVLSGSPEHF 317
PKA P + P+Q+ R H SSP PK V SG+P
Sbjct: 796 RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH--PK-VKSGTPPRQ 852
Query: 318 ------QKHRSGSSPEHARHSGGSPEHLQK------HALGGSLEHLPRARGTSPEHLKQH 365
Q + +P+ SP+ K H+ GS PR + ++P
Sbjct: 853 GSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSP--PRVKSSTPPRQSPS 910
Query: 366 YGGSPDHK 373
SP K
Sbjct: 911 RSSSPQPK 918
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/157 (27%), Positives = 63/157 (40%), Gaps = 14/157 (8%)
Query: 184 RCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSE 243
R S S +S ++S++ SS+SS+ S+ S + P+ L KP S
Sbjct: 2606 RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASP 2665
Query: 244 GSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPE 303
P + RS SP P + ++L E +P + SP Q+ SS E
Sbjct: 2666 KKPPPGERRSRSPRKP-----IDSLRDSRSLSYSPVERRRPSPQPSPRDQQ----SSSSE 2716
Query: 304 TLPKHVLSG---SPEHFQKHRSGSSPEHARH-SGGSP 336
+ G SP H ++ R SP RH S SP
Sbjct: 2717 RGSRRGQRGDSRSPSH-KRRRETPSPRPMRHRSSRSP 2752
Score = 38.5 bits (88), Expect = 0.016
Identities = 62/249 (24%), Positives = 87/249 (34%), Gaps = 18/249 (7%)
Query: 212 STSSTGSTDS--PDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPD 269
S SS+ T S P H+ S SPE +K RS + RSAS + G
Sbjct: 1709 SASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS-----RRRRSASSPRTKTTSRRGRSP 1763
Query: 270 RPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHA 329
PK +G + + + +R GSS T + S S + R G S H+
Sbjct: 1764 SPKP-RGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822
Query: 330 RHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSR 389
R SP Q+ + S R+R + SP S S + SR
Sbjct: 1823 R----SPAR-QESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR 1877
Query: 390 EGT---LRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLP--QASQNR 444
T RR+++ SP R T R + V + +R P +
Sbjct: 1878 SRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRS 1937
Query: 445 RQPPTRNSS 453
R P TR S
Sbjct: 1938 RTPTTRRRS 1946
Score = 36.6 bits (83), Expect = 0.062
Identities = 62/282 (21%), Positives = 93/282 (32%), Gaps = 25/282 (8%)
Query: 200 TAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHP 259
++PY D S+T + SP+ +P L R GSP+ S E P
Sbjct: 332 SSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE-P 390
Query: 260 QKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQ- 318
P + +P R ++ P+ + L + S + P P P + +H S SPE +
Sbjct: 391 VNPPSEASPTRDRS----PPKSPEKLPQSSSSESSPPSP--QPTKVSRHA-SSSPESPKP 443
Query: 319 -----KHRS-GSSPEHARHSGG------SPEHLQKHALGGSLEHLPRARGTS----PEHL 362
HR SSP S G S H +G S RG S P
Sbjct: 444 APAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKR 503
Query: 363 KQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQ 422
SP + + G S R G R + S G + S
Sbjct: 504 GHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSH 563
Query: 423 LEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRAR 464
+ + +R + ++R + P R S R+R
Sbjct: 564 SRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605
Score = 33.5 bits (75), Expect = 0.52
Identities = 65/247 (26%), Positives = 86/247 (34%), Gaps = 45/247 (18%)
Query: 233 SPEHL-QKPRSEGSPEH------SKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPL 285
SPE L Q SE SP S+H S+SPE P KP P+P H+ +
Sbjct: 408 SPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP-KP-------------APAPGSHREI 453
Query: 286 CKGSPEQQRHPHPGSSPETLPKHV------LSGSPEHFQKHRSGS-SPEHARHS-GGSPE 337
SP + H + + H S SP ++ RS S +P HS SP+
Sbjct: 454 -SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQ 512
Query: 338 HLQKHAL---GGSLEHLPRARGTSPE-------HLKQHYGGSPDHKHGGGSGGSGGSGGG 387
+ + G S R R SP+ Q G S + G S + G
Sbjct: 513 WRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGR 572
Query: 388 SREGT-LRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQ 446
SR T RR +P R S S R R R P ++R +
Sbjct: 573 SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGR----SRSRTPARRRSRTR 628
Query: 447 PPTRNSS 453
P R S
Sbjct: 629 SPVRRRS 635
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 48.1 bits (113), Expect = 2e-05
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 60 EAEKVSAMLDHSNLIREVNRRLQLHLGEIR----GLKDINQKLQEDNQELRDLCCFLDDD 115
E E+++ +LD N + E+NR L +G+++ GL+ N KLQE+ D C L ++
Sbjct: 189 EHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQEE 248
Query: 116 ----RQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVL 171
R++ + + ++ T E+ Y Q + L+ +V K+ E K++ +
Sbjct: 249 QQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLE 308
Query: 172 LDEE 175
L++E
Sbjct: 309 LEKE 312
Score = 30.0 bits (66), Expect = 5.8
Identities = 27/118 (22%), Positives = 54/118 (45%), Gaps = 25/118 (21%)
Query: 58 RAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQ 117
++E E+ A+ ++ + L++ L ++ GLK ++LQ++ EL+ +C
Sbjct: 444 KSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKIC-------- 495
Query: 118 KGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEE 175
+ Q L +E+ L+L + K +K E++ + N LK L D+E
Sbjct: 496 -----EEQEQAL---------QEMGLHLSQSK---LKMEDIKEVNQALKGHAWLKDDE 536
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 48.1 bits (113), Expect = 2e-05
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 60 EAEKVSAMLDHSNLIREVNRRLQLHLGEIR----GLKDINQKLQEDNQELRDLCCFLDDD 115
E E+++ +LD N + E+NR L +G+++ GL+ N KLQE+ D C L ++
Sbjct: 189 EHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQEE 248
Query: 116 ----RQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVL 171
R++ + + ++ T E+ Y Q + L+ +V K+ E K++ +
Sbjct: 249 QQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLE 308
Query: 172 LDEE 175
L++E
Sbjct: 309 LEKE 312
Score = 30.0 bits (66), Expect = 5.8
Identities = 27/118 (22%), Positives = 54/118 (45%), Gaps = 25/118 (21%)
Query: 58 RAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQ 117
++E E+ A+ ++ + L++ L ++ GLK ++LQ++ EL+ +C
Sbjct: 444 KSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKIC-------- 495
Query: 118 KGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEE 175
+ Q L +E+ L+L + K +K E++ + N LK L D+E
Sbjct: 496 -----EEQEQAL---------QEMGLHLSQSK---LKMEDIKEVNQALKGHAWLKDDE 536
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 48.1 bits (113), Expect = 2e-05
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 60 EAEKVSAMLDHSNLIREVNRRLQLHLGEIR----GLKDINQKLQEDNQELRDLCCFLDDD 115
E E+++ +LD N + E+NR L +G+++ GL+ N KLQE+ D C L ++
Sbjct: 297 EHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQEE 356
Query: 116 ----RQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVL 171
R++ + + ++ T E+ Y Q + L+ +V K+ E K++ +
Sbjct: 357 QQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLE 416
Query: 172 LDEE 175
L++E
Sbjct: 417 LEKE 420
Score = 30.0 bits (66), Expect = 5.8
Identities = 27/118 (22%), Positives = 54/118 (45%), Gaps = 25/118 (21%)
Query: 58 RAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQ 117
++E E+ A+ ++ + L++ L ++ GLK ++LQ++ EL+ +C
Sbjct: 552 KSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKIC-------- 603
Query: 118 KGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEE 175
+ Q L +E+ L+L + K +K E++ + N LK L D+E
Sbjct: 604 -----EEQEQAL---------QEMGLHLSQSK---LKMEDIKEVNQALKGHAWLKDDE 644
>gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]
Length = 373
Score = 47.4 bits (111), Expect = 3e-05
Identities = 49/170 (28%), Positives = 64/170 (37%), Gaps = 18/170 (10%)
Query: 356 GTSPEHLKQHYGGSPDHKH-GGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNE 414
G E L H G P H GG GGS G GGG+R R + G P R +
Sbjct: 179 GQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRL-LGS 237
Query: 415 STLSYVRQLEARVRQLEEENRMLPQASQNR--------RQPPTRNSSNMEKGWGSRARRV 466
+ R AR QL + + +S+ R PTR + + RAR
Sbjct: 238 AERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR-- 295
Query: 467 LQWWQGCRGIGRCLPTLPGSFRLSSGADG-SNSSP-NSAASFSGHATPSQ 514
GC + P+ PG + G G N+ P S A FS H S+
Sbjct: 296 ----GGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPFSPHPHASR 341
>gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]
Length = 373
Score = 47.4 bits (111), Expect = 3e-05
Identities = 49/170 (28%), Positives = 64/170 (37%), Gaps = 18/170 (10%)
Query: 356 GTSPEHLKQHYGGSPDHKH-GGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNE 414
G E L H G P H GG GGS G GGG+R R + G P R +
Sbjct: 179 GQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRL-LGS 237
Query: 415 STLSYVRQLEARVRQLEEENRMLPQASQNR--------RQPPTRNSSNMEKGWGSRARRV 466
+ R AR QL + + +S+ R PTR + + RAR
Sbjct: 238 AERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR-- 295
Query: 467 LQWWQGCRGIGRCLPTLPGSFRLSSGADG-SNSSP-NSAASFSGHATPSQ 514
GC + P+ PG + G G N+ P S A FS H S+
Sbjct: 296 ----GGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPFSPHPHASR 341
>gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]
Length = 373
Score = 47.4 bits (111), Expect = 3e-05
Identities = 49/170 (28%), Positives = 64/170 (37%), Gaps = 18/170 (10%)
Query: 356 GTSPEHLKQHYGGSPDHKH-GGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNE 414
G E L H G P H GG GGS G GGG+R R + G P R +
Sbjct: 179 GQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRL-LGS 237
Query: 415 STLSYVRQLEARVRQLEEENRMLPQASQNR--------RQPPTRNSSNMEKGWGSRARRV 466
+ R AR QL + + +S+ R PTR + + RAR
Sbjct: 238 AERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR-- 295
Query: 467 LQWWQGCRGIGRCLPTLPGSFRLSSGADG-SNSSP-NSAASFSGHATPSQ 514
GC + P+ PG + G G N+ P S A FS H S+
Sbjct: 296 ----GGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPFSPHPHASR 341
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 47.4 bits (111), Expect = 3e-05
Identities = 59/240 (24%), Positives = 82/240 (34%), Gaps = 23/240 (9%)
Query: 221 SPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPE 280
SP H S H RS SP HRS+S + P ++ +GPS
Sbjct: 1632 SPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSP-------SQRSHRGPSER 1684
Query: 281 HHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEH---ARHSGGSPE 337
H C SP ++RH P P SP + HRS + H + S SP
Sbjct: 1685 SH---C--SPSERRHRSPSQRSHRGPSERRHHSPSK-RSHRSPARRSHRSPSERSHHSPS 1738
Query: 338 HLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQA 397
H+ H P R + H S + +H S S S +
Sbjct: 1739 ERSHHSPSERRHHSPSERSHCSPSERSHCSPS-ERRHRSPSERRHHS--PSEKSHHSPSE 1795
Query: 398 QEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEK 457
+ SP R +S + S S L R + E R ++ R+ R+ S EK
Sbjct: 1796 RSHHSPSERRRHSPLERSRHS----LLERSHRSPSERRSHRSFERSHRRISERSHSPSEK 1851
Score = 46.6 bits (109), Expect = 6e-05
Identities = 46/179 (25%), Positives = 62/179 (34%), Gaps = 23/179 (12%)
Query: 210 GSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEH---PQKPRACG 266
G + S S P +HH+ S RS S +HRS S P + C
Sbjct: 1629 GLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCS 1688
Query: 267 TPDR------PKALKGPSP-EHHKPLCKG--SPEQQRHPHPGS----SPETLPKHVLSGS 313
+R ++ +GPS HH P + SP ++ H P SP H S
Sbjct: 1689 PSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSER 1748
Query: 314 PEHFQKHRSGSSPEHARHSG------GSPEHLQKHALGGSLEHLPRARG-TSPEHLKQH 365
H RS SP H SP + H+ H P R SP ++H
Sbjct: 1749 RHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRH 1807
Score = 43.9 bits (102), Expect = 4e-04
Identities = 58/224 (25%), Positives = 75/224 (33%), Gaps = 38/224 (16%)
Query: 215 STGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKP--RACGTPDRPK 272
S S SP HH+ S H RS SP H S S + P R +P
Sbjct: 1730 SERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKS 1789
Query: 273 ALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVL----SGSPEHFQKHRS------ 322
HH P E++RH SP +H L SP + HRS
Sbjct: 1790 HHSPSERSHHSP-----SERRRH-----SPLERSRHSLLERSHRSPSERRSHRSFERSHR 1839
Query: 323 -----GSSPEHARH------SGGSPEHLQKHALGGSLEHLPRARG-TSPEHLKQHYGGSP 370
SP H S SP + H+ G H P R SP ++Q G +
Sbjct: 1840 RISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQ--GRTS 1897
Query: 371 DHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNE 414
+ H + S R G R + SP R+ S + E
Sbjct: 1898 ERSHRSSCERTRHSPSEMRPG--RPSGRNHCSPSERSRRSPLKE 1939
Score = 38.5 bits (88), Expect = 0.016
Identities = 56/245 (22%), Positives = 75/245 (30%), Gaps = 28/245 (11%)
Query: 221 SPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASP---EHPQKPRACGTPDR------P 271
SP +S H RS SP H S S P + C P+R
Sbjct: 1568 SPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSE 1627
Query: 272 KALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEH--- 328
+ L PS H+ P Q+RH P P S ++HRS S H
Sbjct: 1628 RGLHSPSQRSHR-----GPSQRRHHSPSERSHRSPSERSHRSSSE-RRHRSPSQRSHRGP 1681
Query: 329 ARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGS 388
+ S SP ++H H RG P + H H+ S
Sbjct: 1682 SERSHCSPSE-RRHRSPSQRSH----RG--PSERRHHSPSKRSHRSPARRSHRSPSERSH 1734
Query: 389 REGTLRRQAQEDGSPHHR-NVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQP 447
+ R HH + S + S S+ E R R E P S+
Sbjct: 1735 HSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSP--SEKSHHS 1792
Query: 448 PTRNS 452
P+ S
Sbjct: 1793 PSERS 1797
Score = 37.4 bits (85), Expect = 0.036
Identities = 45/201 (22%), Positives = 59/201 (29%), Gaps = 15/201 (7%)
Query: 212 STSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRP 271
S+ S S SP H + H R SP HR S P
Sbjct: 1599 SSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSP-------SE 1651
Query: 272 KALKGPSPEHHKPLCK---GSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEH 328
++ + PS H+ + SP Q+ H P P SP + HR S H
Sbjct: 1652 RSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQ-RSHRGPSERRH 1710
Query: 329 ---ARHSGGSPEHLQKHALGGSLEHLPRARG-TSPEHLKQHYGGSPDHKHGGGSGGSGGS 384
++ S SP + H P R SP + H H S
Sbjct: 1711 HSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPS 1770
Query: 385 GGGSREGTLRRQAQEDGSPHH 405
R + RR HH
Sbjct: 1771 ERRHRSPSERRHHSPSEKSHH 1791
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 47.0 bits (110), Expect = 5e-05
Identities = 63/325 (19%), Positives = 104/325 (32%), Gaps = 27/325 (8%)
Query: 214 SSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKA 273
S + SP+ + H+ S SP + SP ++ RS S P K R C P
Sbjct: 387 SGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRS-RSPNKARDCSRSRSPYK 445
Query: 274 LKGPSPEHHKPLCKG-----SPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSP-- 326
+ S + SP + R SP H GSP + HR SP
Sbjct: 446 ARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSK 505
Query: 327 --------------EHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQH-YGGSPD 371
+H R S E ++ + + E R++ SP ++H SP
Sbjct: 506 ERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKER-DRSQSRSPSEEREHRQSRSPS 564
Query: 372 HKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLE 431
+ S R+ + ++ N SG + S + +R R
Sbjct: 565 KERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPS 624
Query: 432 EENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQG---CRGIGRCLPTLPGSFR 488
+E + ++ P++++ W R Q + T P +
Sbjct: 625 KEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQ 684
Query: 489 LSSGADGSNSSPNSAASFSGHATPS 513
S D + S A+ G + S
Sbjct: 685 TLSQDDSQADATTSKATLPGERSSS 709
Score = 37.4 bits (85), Expect = 0.036
Identities = 58/249 (23%), Positives = 85/249 (34%), Gaps = 26/249 (10%)
Query: 211 SSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDR 270
S S + S + H S SP GSP + S S P K R DR
Sbjct: 360 SKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS-RSPNKAR-----DR 413
Query: 271 PKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHA- 329
++ + P + + SP + R SP S SP + H SP A
Sbjct: 414 SRS-RSPYKARDRSRSR-SPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKAR 471
Query: 330 -RHSGGSPEHLQKHA-LGGSLEHLPRARGTSP---EHLKQHYGGSPDHKHGGGSGGSGGS 384
R SP + H+ LG + R SP +Q S + H
Sbjct: 472 DRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDH---------- 521
Query: 385 GGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNR 444
SR + RQ ++ SP+ S + S ++R E + R S+ R
Sbjct: 522 -RRSRSPSKERQRRQSRSPNKERDRS-QSRSPSEEREHRQSRSPSKERDRRRWRSPSKER 579
Query: 445 RQPPTRNSS 453
+ +R+SS
Sbjct: 580 ERRQSRSSS 588
Score = 30.4 bits (67), Expect = 4.4
Identities = 52/223 (23%), Positives = 75/223 (33%), Gaps = 30/223 (13%)
Query: 248 HSKHRSASPEHPQKPRACGTPDRPKA---LKGPSPEHHKPLCKGSPEQQRHPHPGSSPET 304
HS+ RS S Q TP R ++ + PS E + S +++ H SSP
Sbjct: 329 HSQSRSHSKGKSQNQSR--TPRRGRSHNWSRNPSKERSHSHSRSSSKERDH-RGSSSPRK 385
Query: 305 LPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQ----------KHALGGSLEHLP-- 352
SGSP + H SP AR S + A S P
Sbjct: 386 ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYK 445
Query: 353 ---RARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSP-HHRNV 408
R+R SP + H +K S SR + R + GSP R+
Sbjct: 446 ARDRSRSRSPNKARDHSRSRSPNKARDRS--------RSRSPSKERDHSQLGSPSKERDH 497
Query: 409 YSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRN 451
+ S RQ + ++ + P + RRQ + N
Sbjct: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN 540
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 46.6 bits (109), Expect = 6e-05
Identities = 54/238 (22%), Positives = 91/238 (38%), Gaps = 19/238 (7%)
Query: 143 LYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGCAGSRCSIDSQASLCQLTASTAP 202
LY +K + E+ ++EV K + L+E + + KG G+ ++ + + ++P
Sbjct: 288 LYTRKKPNYELLEKEVEKRKVALQEAKL---KAKGLNPDGTP-ALSTLGGFSPASKPSSP 343
Query: 203 YVRDVGDGSSTSSTGSTDSPDHHKHHASSGSP-----EHLQKPRSEGSPEHSKHRSASPE 257
+ S S T + +S SP + ++ R+ S S+ R+ S
Sbjct: 344 REVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRS 403
Query: 258 HPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHV---LSGSP 314
PR R ++ G + + E R H SP KH L S
Sbjct: 404 RSHTPRRHYNNRRSRS--GTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSN 461
Query: 315 EHFQKH---RSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGS 369
H K RS S + HS + +H +H G + R+R H +H+GGS
Sbjct: 462 RHGHKRKKSRSRSQSKSRDHSDAAKKH--RHERGHHRDRRERSRSFERSHKSKHHGGS 517
Score = 33.5 bits (75), Expect = 0.52
Identities = 38/154 (24%), Positives = 46/154 (29%), Gaps = 20/154 (12%)
Query: 198 ASTAPY--VRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSAS 255
AS +PY VR S S + S S H RS S+ RS S
Sbjct: 371 ASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRS 430
Query: 256 PEHPQKPRACGTPDRPKA--------LKGPSPEHHKPLCKGSPEQ----------QRHPH 297
H + PR P LK + HK S Q ++H H
Sbjct: 431 RSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRH 490
Query: 298 PGSSPETLPKHVLSGSPEHFQKHRSGSSPEHARH 331
+ S H KH GS H RH
Sbjct: 491 ERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRH 524
>gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo
sapiens]
Length = 685
Score = 46.6 bits (109), Expect = 6e-05
Identities = 65/278 (23%), Positives = 104/278 (37%), Gaps = 33/278 (11%)
Query: 143 LYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGCAGSRCSIDSQASLCQLTASTAP 202
L L + K E + +VVK++ E L E + R +++ L + AP
Sbjct: 173 LRLAEKKQFEPVEIKVVKKSEERPMTAEELREREFLERKHRRKKLETDGKLPPTVSKKAP 232
Query: 203 YVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHR--SASPEHPQ 260
++ + S GS D +H +S G P + +S S + KH S+S P
Sbjct: 233 SQKE--SVGTKLSKGSGD-----RHPSSKGMPLPHAEKKSRPSMANEKHLALSSSKSMPG 285
Query: 261 K--PRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQ 318
+ G +P +G H KP+ G+ + PH +S ++PK S + +
Sbjct: 286 ERIKAGSGNSSQPSLREG----HDKPVFNGAGK----PHSSTSSPSVPKTSASRTQKSAV 337
Query: 319 KHRSGSSPEHARHSGGSPEHLQKHAL--------GGSLEHLPRARGTSPEHLKQHYGGSP 370
+H++ S H HS P + G S P T G P
Sbjct: 338 EHKAKKSLSHPSHSRPGPMVTPHNKAKSPGVRQPGSSSSSAPGQPSTGVARPTVSSGPVP 397
Query: 371 DHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNV 408
++G S G S GS++ T D +P R V
Sbjct: 398 RRQNGSSSSGPERSISGSKKPT------NDSNPSRRTV 429
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 46.2 bits (108), Expect = 8e-05
Identities = 68/281 (24%), Positives = 87/281 (30%), Gaps = 65/281 (23%)
Query: 271 PKALKGPSP------EHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGS 324
P + GPSP K L P H HP P H P H H
Sbjct: 967 PASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHP---PHHHHHHAPPPQPHHHHAH---- 1019
Query: 325 SPEHA--RHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSG 382
P H +GGSP+ G L RG P G+P H G +GG G
Sbjct: 1020 -PPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTP----GAPSPSHHGSAGGGG 1074
Query: 383 GS-------------------------GGGSREGTLRRQAQEDGSPHHRNVYSGMNESTL 417
GS G R+G L +Q + +G P T
Sbjct: 1075 GSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTS 1134
Query: 418 SYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIG 477
Q V E+N +P + + P T +S +G + A
Sbjct: 1135 PASPQPPPAVAAPSEKN-SIPIPTIIIKAPSTSSSGRSSQGSSTEAEP------------ 1181
Query: 478 RCLPTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEP 518
PT P + G G SSP+ A + S PS P P
Sbjct: 1182 ---PTQP---EPTGGGGGGGSSPSPAPAMS-PVPPSPSPVP 1215
Score = 32.7 bits (73), Expect = 0.89
Identities = 28/75 (37%), Positives = 33/75 (44%), Gaps = 23/75 (30%)
Query: 321 RSGSSPEHAR----HSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGG 376
RS SSP AR G PE ++ PR R +S G+P G
Sbjct: 487 RSASSPRGARARSPSRGRHPEDAKRQ---------PRGRPSS--------SGTPREGPAG 529
Query: 377 GSGGSGGSGG--GSR 389
G+GGSGG GG GSR
Sbjct: 530 GTGGSGGPGGSLGSR 544
Score = 29.3 bits (64), Expect = 9.8
Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 3/88 (3%)
Query: 184 RCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRS- 242
R + D+ +L +AP G TS + P SSG+ PR
Sbjct: 436 RANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGA 495
Query: 243 -EGSPEHSKHRSASPEHPQ-KPRACGTP 268
SP +H + P+ +P + GTP
Sbjct: 496 RARSPSRGRHPEDAKRQPRGRPSSSGTP 523
>gi|229577273 BUD13 homolog isoform 2 [Homo sapiens]
Length = 485
Score = 45.8 bits (107), Expect = 1e-04
Identities = 71/292 (24%), Positives = 99/292 (33%), Gaps = 53/292 (18%)
Query: 177 GAGCAGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDS-PDHHKHHAS--SGS 233
GAG G R +D S ++ + + DG D P+ K + S +
Sbjct: 43 GAGGKGMRI-VDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSA 101
Query: 234 PEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPE---HHKPLCKGSP 290
L +E P + R +P+ + GTPD PSP H P SP
Sbjct: 102 KWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPD-------PSPRKDRHDTP--DPSP 152
Query: 291 EQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSG--SSPEHARHSG--GSPEHLQKHALGG 346
+ RH P SP +H SP +H S S P ARH SP +H G
Sbjct: 153 RRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG 212
Query: 347 SLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHR 406
+ + T + SP HK G S R R + D SP R
Sbjct: 213 DCQ-----KATDSDL------SSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRR 261
Query: 407 NVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKG 458
+ ++S LS R R QPP + +++M G
Sbjct: 262 RQRTKSSDSDLSPPR----------------------RSQPPGKKAAHMYSG 291
>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
Length = 525
Score = 45.8 bits (107), Expect = 1e-04
Identities = 58/213 (27%), Positives = 69/213 (32%), Gaps = 36/213 (16%)
Query: 223 DHHKHHASSGSPEHLQKPRSEGSPEHSK--------HRSASPEHPQKPRACGTP----DR 270
D +H +G P HL P G E S H S HP KP G P +R
Sbjct: 245 DPQEHENINGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDER 304
Query: 271 PKALKGPSPEHHKPL-------CK----GSPEQQRHPHPGSSPETLP----KHVLSGSPE 315
+ P P+ PL C+ G+ QRH H +S + P H
Sbjct: 305 DHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGH 364
Query: 316 HFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPE-HLKQHYG--GSPDH 372
H H H +H G H H G H G P H Q YG P H
Sbjct: 365 HPHAHHPHEHDTHRQHPHG--HHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPH 422
Query: 373 KHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHH 405
G G G G R RR + P H
Sbjct: 423 NQGHCCHGHGPPPGHLR----RRGPGKGPRPFH 451
Score = 35.0 bits (79), Expect = 0.18
Identities = 38/151 (25%), Positives = 49/151 (32%), Gaps = 23/151 (15%)
Query: 193 LCQLTASTAPYVRDVGDGSSTSSTGSTDSPDH-HKHHASSGSPEHLQKPRSEGSPEHSKH 251
L ++ S+ + +G+ S + S H HKHH+ P H P + EH H
Sbjct: 319 LLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHP-HGHHPHAHHPHEHDTH 377
Query: 252 RSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKG---------SPEQQRHPHPGSSP 302
R +HP G G P H P C P Q H G P
Sbjct: 378 R----QHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHGHGP 433
Query: 303 ETLPKHVLSGSPEHFQKHRSGSSPEHARHSG 333
P H+ P G P H R G
Sbjct: 434 P--PGHLRRRGP------GKGPRPFHCRQIG 456
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 44.7 bits (104), Expect = 2e-04
Identities = 90/358 (25%), Positives = 126/358 (35%), Gaps = 79/358 (22%)
Query: 13 AAAESCSPAPAGSSAAPPAPVEDLSKV---------------SDEELLQWSKEELIRSLR 57
AA + SP PA APP DL + S + + L +L
Sbjct: 178 AAFSNLSPPPA---PAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALE 234
Query: 58 RAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQ 117
A+ E A L L E R LQ GE++ L++ + NQ RD+
Sbjct: 235 AAQGEARGAQLREEQLQAECER-LQ---GELKQLQETRAQDLASNQSERDMAWV------ 284
Query: 118 KGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKG 177
KRV + L + + E+ L +L++L Q +++ LL E+
Sbjct: 285 --KRVGDDQVNLA-----LAYTELTEELGRLRELSSLQGRILR---------TLLQEQAR 328
Query: 178 AGCAGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHL 237
+G G R S SQ S AP + SP +
Sbjct: 329 SG--GQRHSPLSQRH------SPAPQC-------------PSPSPPARAAPPCPPCQSPV 367
Query: 238 QKPRSEGSPEHSKHRSASPEHPQKPRACGTPDR----PKALKGPSPEHHKPLCKGSPEQQ 293
+ RS P S + SP P P P R P + + PSP+ P+ P Q
Sbjct: 368 PQRRSPVPPCPSPQQRRSPASPSCPSP--VPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQ 425
Query: 294 RHPHPGSSP--ETLPKHVLSGSPEH-----FQKHRSGSS-PEHARHSGGSPEHLQKHA 343
P P P TL + + P H FQ RS S E A ++G SP LQ A
Sbjct: 426 PRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEA 483
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 43.9 bits (102), Expect = 4e-04
Identities = 55/213 (25%), Positives = 79/213 (37%), Gaps = 26/213 (12%)
Query: 208 GDGSSTSSTGSTDSPDHHKHH--ASSGSPEHLQKPRSEGSPEHSKH----RSASPEH--P 259
G S++SS+ S+ HH HH S G L +S+ H+++ A P + P
Sbjct: 1226 GQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPP 1285
Query: 260 QKPRACGTPDRPKALK-----GPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSP 314
Q+P P +P L P P P+ P + H H P P+H G P
Sbjct: 1286 QQPSLPPPPQQPPPLPQLGSIPPPPASAPPV---GPHRHFHAH---GPVPGPQHYTLGRP 1339
Query: 315 EHFQKHRSGSSPEHARHSGGSPEHLQKHAL---GGSLEHLPRARGTSPEHLKQHYGGSPD 371
+ +G P+ A H G P H L + +H P A P+H + P
Sbjct: 1340 GRAPRRGAGGHPQFAPH-GRHPLHQPTSPLPLYSPAPQH-PPAHKQGPKHF--IFSHHPQ 1395
Query: 372 HKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPH 404
G+ G GS + Q SPH
Sbjct: 1396 MMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPH 1428
Score = 32.3 bits (72), Expect = 1.2
Identities = 27/95 (28%), Positives = 34/95 (35%), Gaps = 9/95 (9%)
Query: 215 STGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKAL 274
+ G+ P S P H Q P S SP H S P P P TP P
Sbjct: 1399 AAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSP-IPPHPSYPPLPPPSPH---TPHSPL-- 1452
Query: 275 KGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHV 309
P H PL P +P P ++P+ P +
Sbjct: 1453 --PPTSPHGPLHASGPPGTANP-PSANPKAKPSRI 1484
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 43.5 bits (101), Expect = 5e-04
Identities = 47/171 (27%), Positives = 63/171 (36%), Gaps = 24/171 (14%)
Query: 219 TDSPDHHKHHASSGSPEHLQKPR-----SEGSPEHSKHRSASPEHPQKPRACGT----PD 269
++S + +H AS E L KPR SE P H S + E P KPR + P
Sbjct: 224 SESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELP-KPRISDSESEDPP 282
Query: 270 RPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHA 329
R +A + E KP S + P S ET + H QK S +
Sbjct: 283 RNQASDSENEELPKPRVSDSESEGPQKGPASDSET------EDASRHKQKPESDDDSD-- 334
Query: 330 RHSGGSPEHLQKHALGGSLEHLPRAR-----GTSPEHLKQHYGGSPDHKHG 375
R + G +Q + S H+ R + EH KQ D K G
Sbjct: 335 RENKGEDTEMQNDSF-HSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEG 384
Score = 38.5 bits (88), Expect = 0.016
Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 16/169 (9%)
Query: 219 TDSPDHHKHHASSGSPEHLQK-PRSEGSPEHS-KHRSASPEHPQKPRACGT------PDR 270
+++ D KH AS E LQK P S+ E + K + + E + PR + P +
Sbjct: 146 SENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPK 205
Query: 271 PKALKGPSPEHHKPLCKGSPEQQ--RHPHPGSSPETLPKHVLSGS-PEHFQKHRSGSS-- 325
P+ S E KP S ++ RH S E LPK +S S E +H++ S
Sbjct: 206 PRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSEN 265
Query: 326 ---PEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPD 371
P+ S + + A E LP+ R + E G + D
Sbjct: 266 EELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASD 314
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,283,425
Number of Sequences: 37866
Number of extensions: 1658558
Number of successful extensions: 17057
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 234
Number of HSP's successfully gapped in prelim test: 659
Number of HSP's that attempted gapping in prelim test: 12237
Number of HSP's gapped (non-prelim): 4022
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.