Guide to the Human Genome
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Search of human proteins with 28559069

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a
[Homo sapiens]
         (912 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Ho...  1905   0.0  
gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Ho...  1905   0.0  
gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b [Ho...  1471   0.0  
gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6 [H...   830   0.0  
gi|28559061 DNA cytosine-5 methyltransferase 3 beta isoform 2 [H...   830   0.0  
gi|5901940 DNA cytosine-5 methyltransferase 3 beta isoform 1 [Ho...   825   0.0  
gi|28559063 DNA cytosine-5 methyltransferase 3 beta isoform 3 [H...   650   0.0  
gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c [Ho...   308   2e-83
gi|28872780 cytosine-5-methyltransferase 3-like protein isoform ...   253   6e-67
gi|28872778 cytosine-5-methyltransferase 3-like protein isoform ...   253   7e-67
gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]         66   2e-10
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]        60   1e-08
gi|51873049 hypothetical protein LOC8603 [Homo sapiens]                56   1e-07
gi|38176300 nestin [Homo sapiens]                                      54   7e-07
gi|157738619 smoothelin-like 1 [Homo sapiens]                          51   4e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     49   2e-05
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              48   4e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    48   5e-05
gi|33286446 opioid growth factor receptor [Homo sapiens]               46   1e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    46   2e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    45   2e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    45   3e-04
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    45   3e-04
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    45   3e-04
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    45   3e-04
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    45   3e-04
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    44   5e-04
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    44   7e-04
gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]            44   7e-04
gi|11560152 zinc finger protein 335 [Homo sapiens]                     44   7e-04

>gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score = 1905 bits (4935), Expect = 0.0
 Identities = 912/912 (100%), Positives = 912/912 (100%)

Query: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60
           MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV
Sbjct: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60

Query: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120
           ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG
Sbjct: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120

Query: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSL 180
           AAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSL
Sbjct: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSL 180

Query: 181 RQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVE 240
           RQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVE
Sbjct: 181 RQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVE 240

Query: 241 EASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKL 300
           EASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKL
Sbjct: 241 EASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKL 300

Query: 301 RGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYN 360
           RGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYN
Sbjct: 301 RGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYN 360

Query: 361 KQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPK 420
           KQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPK
Sbjct: 361 KQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPK 420

Query: 421 GLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLV 480
           GLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLV
Sbjct: 421 GLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLV 480

Query: 481 YEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTIC 540
           YEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTIC
Sbjct: 481 YEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTIC 540

Query: 541 CGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRRED 600
           CGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRRED
Sbjct: 541 CGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRRED 600

Query: 601 WPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRY 660
           WPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRY
Sbjct: 601 WPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRY 660

Query: 661 IASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPAR 720
           IASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPAR
Sbjct: 661 IASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPAR 720

Query: 721 KGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMI 780
           KGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMI
Sbjct: 721 KGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMI 780

Query: 781 DAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSI 840
           DAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSI
Sbjct: 781 DAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSI 840

Query: 841 KQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRH 900
           KQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRH
Sbjct: 841 KQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRH 900

Query: 901 LFAPLKEYFACV 912
           LFAPLKEYFACV
Sbjct: 901 LFAPLKEYFACV 912


>gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score = 1905 bits (4935), Expect = 0.0
 Identities = 912/912 (100%), Positives = 912/912 (100%)

Query: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60
           MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV
Sbjct: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60

Query: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120
           ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG
Sbjct: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120

Query: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSL 180
           AAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSL
Sbjct: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSL 180

Query: 181 RQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVE 240
           RQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVE
Sbjct: 181 RQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVE 240

Query: 241 EASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKL 300
           EASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKL
Sbjct: 241 EASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKL 300

Query: 301 RGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYN 360
           RGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYN
Sbjct: 301 RGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYN 360

Query: 361 KQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPK 420
           KQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPK
Sbjct: 361 KQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPK 420

Query: 421 GLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLV 480
           GLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLV
Sbjct: 421 GLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLV 480

Query: 481 YEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTIC 540
           YEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTIC
Sbjct: 481 YEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTIC 540

Query: 541 CGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRRED 600
           CGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRRED
Sbjct: 541 CGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRRED 600

Query: 601 WPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRY 660
           WPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRY
Sbjct: 601 WPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRY 660

Query: 661 IASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPAR 720
           IASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPAR
Sbjct: 661 IASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPAR 720

Query: 721 KGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMI 780
           KGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMI
Sbjct: 721 KGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMI 780

Query: 781 DAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSI 840
           DAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSI
Sbjct: 781 DAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSI 840

Query: 841 KQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRH 900
           KQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRH
Sbjct: 841 KQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRH 900

Query: 901 LFAPLKEYFACV 912
           LFAPLKEYFACV
Sbjct: 901 LFAPLKEYFACV 912


>gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b [Homo
           sapiens]
          Length = 723

 Score = 1471 bits (3809), Expect = 0.0
 Identities = 699/699 (100%), Positives = 699/699 (100%)

Query: 214 AEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKN 273
           AEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKN
Sbjct: 25  AEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKN 84

Query: 274 ATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGD 333
           ATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGD
Sbjct: 85  ATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGD 144

Query: 334 GKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDES 393
           GKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDES
Sbjct: 145 GKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDES 204

Query: 394 DTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPP 453
           DTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPP
Sbjct: 205 DTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPP 264

Query: 454 AKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGM 513
           AKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGM
Sbjct: 265 AKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGM 324

Query: 514 CQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQ 573
           CQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQ
Sbjct: 325 CQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQ 384

Query: 574 AAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKP 633
           AAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKP
Sbjct: 385 AAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKP 444

Query: 634 IRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQK 693
           IRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQK
Sbjct: 445 IRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQK 504

Query: 694 HIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFW 753
           HIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFW
Sbjct: 505 HIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFW 564

Query: 754 LFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKL 813
           LFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKL
Sbjct: 565 LFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKL 624

Query: 814 ELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVH 873
           ELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVH
Sbjct: 625 ELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVH 684

Query: 874 YTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV 912
           YTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV
Sbjct: 685 YTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV 723


>gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6 [Homo
           sapiens]
          Length = 845

 Score =  830 bits (2145), Expect = 0.0
 Identities = 395/646 (61%), Positives = 486/646 (75%), Gaps = 12/646 (1%)

Query: 266 GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 325
           G ++    A     D  EY+DG+ FGIG+LVWGK++GFSWWP  +VSW  T + +A  G 
Sbjct: 211 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 270

Query: 326 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 385
           RWV WFGDGKFS V  +KL+ L  F   F+ AT+NK   YRKA+Y  L+ A  RAGK FP
Sbjct: 271 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 330

Query: 386 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEA 445
                  S    ++E Q KPM+EWA GGF+P+G +GL+P   +  P  +       +   
Sbjct: 331 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQ--PENKTRRRTADDSAT 381

Query: 446 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 505
           + Y P P   K       K +  E   +++RE++  +V     ++ED C+SCG  N    
Sbjct: 382 SDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNKSSLEDGCLSCGRKNPVSF 438

Query: 506 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 565
           HPLF GG+CQ C++ FLE  Y YDDDGYQSYCT+CC GRE+L+C N +CCRCFCVEC+++
Sbjct: 439 HPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEV 498

Query: 566 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 625
           LVG G A  A  ++PW+CYMC  +  +G+LRRR+DW  RLQ FF ++   E++ PK+YP 
Sbjct: 499 LVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEAPKLYPA 558

Query: 626 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 685
           +PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE+SI VG V+H+G I YV 
Sbjct: 559 IPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEGNIKYVN 618

Query: 686 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 745
           DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGTGRLFFEFY LL+ +RPKE
Sbjct: 619 DVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYSRPKE 678

Query: 746 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPL 805
           GDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSAAHRARYFWGNLPGMNRP+
Sbjct: 679 GDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLPGMNRPV 738

Query: 806 ASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEME 865
            ++ NDKLELQ+CLE+ RIAK  KV+TITT+SNSIKQGK+Q FPV MN KED+LWCTE+E
Sbjct: 739 IASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVLWCTELE 798

Query: 866 RVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFAC 911
           R+FGFPVHYTDVSNM R ARQ+LLGRSWSVPVIRHLFAPLK+YFAC
Sbjct: 799 RIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFAC 844


>gi|28559061 DNA cytosine-5 methyltransferase 3 beta isoform 2 [Homo
           sapiens]
          Length = 833

 Score =  830 bits (2145), Expect = 0.0
 Identities = 395/646 (61%), Positives = 486/646 (75%), Gaps = 12/646 (1%)

Query: 266 GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 325
           G ++    A     D  EY+DG+ FGIG+LVWGK++GFSWWP  +VSW  T + +A  G 
Sbjct: 199 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 258

Query: 326 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 385
           RWV WFGDGKFS V  +KL+ L  F   F+ AT+NK   YRKA+Y  L+ A  RAGK FP
Sbjct: 259 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 318

Query: 386 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEA 445
                  S    ++E Q KPM+EWA GGF+P+G +GL+P   +  P  +       +   
Sbjct: 319 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQ--PENKTRRRTADDSAT 369

Query: 446 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 505
           + Y P P   K       K +  E   +++RE++  +V     ++ED C+SCG  N    
Sbjct: 370 SDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNKSSLEDGCLSCGRKNPVSF 426

Query: 506 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 565
           HPLF GG+CQ C++ FLE  Y YDDDGYQSYCT+CC GRE+L+C N +CCRCFCVEC+++
Sbjct: 427 HPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEV 486

Query: 566 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 625
           LVG G A  A  ++PW+CYMC  +  +G+LRRR+DW  RLQ FF ++   E++ PK+YP 
Sbjct: 487 LVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEAPKLYPA 546

Query: 626 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 685
           +PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE+SI VG V+H+G I YV 
Sbjct: 547 IPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEGNIKYVN 606

Query: 686 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 745
           DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGTGRLFFEFY LL+ +RPKE
Sbjct: 607 DVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYSRPKE 666

Query: 746 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPL 805
           GDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSAAHRARYFWGNLPGMNRP+
Sbjct: 667 GDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLPGMNRPV 726

Query: 806 ASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEME 865
            ++ NDKLELQ+CLE+ RIAK  KV+TITT+SNSIKQGK+Q FPV MN KED+LWCTE+E
Sbjct: 727 IASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVLWCTELE 786

Query: 866 RVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFAC 911
           R+FGFPVHYTDVSNM R ARQ+LLGRSWSVPVIRHLFAPLK+YFAC
Sbjct: 787 RIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFAC 832


>gi|5901940 DNA cytosine-5 methyltransferase 3 beta isoform 1 [Homo
           sapiens]
          Length = 853

 Score =  825 bits (2131), Expect = 0.0
 Identities = 397/664 (59%), Positives = 487/664 (73%), Gaps = 28/664 (4%)

Query: 266 GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 325
           G ++    A     D  EY+DG+ FGIG+LVWGK++GFSWWP  +VSW  T + +A  G 
Sbjct: 199 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 258

Query: 326 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 385
           RWV WFGDGKFS V  +KL+ L  F   F+ AT+NK   YRKA+Y  L+ A  RAGK FP
Sbjct: 259 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 318

Query: 386 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEE-----------------E 428
                  S    ++E Q KPM+EWA GGF+P+G +GL+P                    E
Sbjct: 319 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPVVNKSKVRRAGSRKLE 371

Query: 429 KNPYKEVYTDMWVEPEAAA-YAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKC 487
              Y+        +  A + Y P P   K       K +  E   +++RE++  +V    
Sbjct: 372 SRKYENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNK 428

Query: 488 RNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVL 547
            ++ED C+SCG  N    HPLF GG+CQ C++ FLE  Y YDDDGYQSYCT+CC GRE+L
Sbjct: 429 SSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELL 488

Query: 548 MCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQM 607
           +C N +CCRCFCVEC+++LVG G A  A  ++PW+CYMC  +  +G+LRRR+DW  RLQ 
Sbjct: 489 LCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQA 548

Query: 608 FFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCE 667
           FF ++   E++ PK+YP +PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE
Sbjct: 549 FFTSDTGLEYEAPKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCE 608

Query: 668 DSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGT 727
           +SI VG V+H+G I YV DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGT
Sbjct: 609 ESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGT 668

Query: 728 GRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSA 787
           GRLFFEFY LL+ +RPKEGDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSA
Sbjct: 669 GRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSA 728

Query: 788 AHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQH 847
           AHRARYFWGNLPGMNRP+ ++ NDKLELQ+CLE+ RIAK  KV+TITT+SNSIKQGK+Q 
Sbjct: 729 AHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQL 788

Query: 848 FPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKE 907
           FPV MN KED+LWCTE+ER+FGFPVHYTDVSNM R ARQ+LLGRSWSVPVIRHLFAPLK+
Sbjct: 789 FPVVMNGKEDVLWCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKD 848

Query: 908 YFAC 911
           YFAC
Sbjct: 849 YFAC 852


>gi|28559063 DNA cytosine-5 methyltransferase 3 beta isoform 3 [Homo
           sapiens]
          Length = 770

 Score =  650 bits (1678), Expect = 0.0
 Identities = 310/538 (57%), Positives = 388/538 (72%), Gaps = 12/538 (2%)

Query: 266 GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 325
           G ++    A     D  EY+DG+ FGIG+LVWGK++GFSWWP  +VSW  T + +A  G 
Sbjct: 199 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 258

Query: 326 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 385
           RWV WFGDGKFS V  +KL+ L  F   F+ AT+NK   YRKA+Y  L+ A  RAGK FP
Sbjct: 259 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 318

Query: 386 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEA 445
                  S    ++E Q KPM+EWA GGF+P+G +GL+P   +  P  +       +   
Sbjct: 319 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQ--PENKTRRRTADDSAT 369

Query: 446 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 505
           + Y P P   K       K +  E   +++RE++  +V     ++ED C+SCG  N    
Sbjct: 370 SDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNKSSLEDGCLSCGRKNPVSF 426

Query: 506 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 565
           HPLF GG+CQ C++ FLE  Y YDDDGYQSYCT+CC GRE+L+C N +CCRCFCVEC+++
Sbjct: 427 HPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEV 486

Query: 566 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 625
           LVG G A  A  ++PW+CYMC  +  +G+LRRR+DW  RLQ FF ++   E++ PK+YP 
Sbjct: 487 LVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEAPKLYPA 546

Query: 626 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 685
           +PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE+SI VG V+H+G I YV 
Sbjct: 547 IPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEGNIKYVN 606

Query: 686 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 745
           DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGTGRLFFEFY LL+ +RPKE
Sbjct: 607 DVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYSRPKE 666

Query: 746 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNR 803
           GDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSAAHRARYFWGNLPGMNR
Sbjct: 667 GDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLPGMNR 724


>gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c [Homo
           sapiens]
          Length = 166

 Score =  308 bits (788), Expect = 2e-83
 Identities = 150/151 (99%), Positives = 151/151 (100%)

Query: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60
           MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV
Sbjct: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60

Query: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120
           ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG
Sbjct: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120

Query: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGK 151
           AAETLPEASRAVENGCCTPKEGRGAPAEAG+
Sbjct: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGE 151


>gi|28872780 cytosine-5-methyltransferase 3-like protein isoform 2
           [Homo sapiens]
          Length = 386

 Score =  253 bits (646), Expect = 6e-67
 Identities = 137/341 (40%), Positives = 184/341 (53%), Gaps = 31/341 (9%)

Query: 476 RERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQS 535
           R+ + YEV+   RNIEDICI CGSL V  +HPLF GG+C  CK+ FL+  + YDDDGYQS
Sbjct: 35  RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94

Query: 536 YCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLL 595
           YC+ICC G  +L+CGN +C RC+C ECVD LVGPG +        W CY+C      GLL
Sbjct: 95  YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154

Query: 596 RRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGI 655
           +RR  W S+L+ F+    +   +P +++  VP  +R+P+RVLSLF+ I   L  L  L  
Sbjct: 155 QRRRKWRSQLKAFYDRESE---NPLEMFETVPVWRRQPVRVLSLFEDIKKELTSLGFLES 211

Query: 656 QVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSI 715
             D                    G++ +V DV    +K ++EWGPFDLV G +P      
Sbjct: 212 GSD-------------------PGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP------ 246

Query: 716 VNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLES 775
             P             F+F+RLL  ARPK G  RPFFW+F + + +   D    SRFLE 
Sbjct: 247 --PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLEM 304

Query: 776 NPVMIDAKEVSAAHRARYFWGNLPGM-NRPLASTVNDKLEL 815
            PV I      +   A   W N+P + +R  A    ++L L
Sbjct: 305 EPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSL 345


>gi|28872778 cytosine-5-methyltransferase 3-like protein isoform 1
           [Homo sapiens]
          Length = 387

 Score =  253 bits (645), Expect = 7e-67
 Identities = 133/326 (40%), Positives = 177/326 (54%), Gaps = 30/326 (9%)

Query: 476 RERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQS 535
           R+ + YEV+   RNIEDICI CGSL V  +HPLF GG+C  CK+ FL+  + YDDDGYQS
Sbjct: 35  RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94

Query: 536 YCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLL 595
           YC+ICC G  +L+CGN +C RC+C ECVD LVGPG +        W CY+C      GLL
Sbjct: 95  YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154

Query: 596 RRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGI 655
           +RR  W S+L+ F+    +   +P +++  VP  +R+P+RVLSLF+ I   L  L  L  
Sbjct: 155 QRRRKWRSQLKAFYDRESE---NPLEMFETVPVWRRQPVRVLSLFEDIKKELTSLGFLES 211

Query: 656 QVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSI 715
             D                    G++ +V DV    +K ++EWGPFDLV G +P      
Sbjct: 212 GSD-------------------PGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP------ 246

Query: 716 VNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLES 775
             P             F+F+RLL  ARPK G  RPFFW+F + + +   D    SRFLE 
Sbjct: 247 --PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLEM 304

Query: 776 NPVMIDAKEVSAAHRARYFWGNLPGM 801
            PV I      +   A   W N+P +
Sbjct: 305 EPVTIPDVHGGSLQNAVRVWSNIPAI 330


>gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]
          Length = 590

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 35/94 (37%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 285 EDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTR--WVMWFGDGKFSVVCVE 342
           EDGR   +G++VWGK+ GF WWP R++   +  +       R   V WFG    S + + 
Sbjct: 483 EDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDGEPSWREAKVSWFGSPTTSFLSIS 542

Query: 343 KLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVA 376
           KL P S F     +    K+ MYRKAI E    A
Sbjct: 543 KLSPFSEFFKL--RFNRKKKGMYRKAITEAANAA 574


>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
          Length = 755

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 70/353 (19%), Positives = 136/353 (38%), Gaps = 60/353 (16%)

Query: 33  RGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGASELLPNGD 92
           + ++++ E ST+     +    R++    SG  P  P V  K      +   S L     
Sbjct: 438 KAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSLP--PRVRLKPQRYRNEENDSSLKTG-- 493

Query: 93  LEK----RSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAE 148
           LEK    +  P+P+    +    G AP+E +                  +P +G   P E
Sbjct: 494 LEKMRSGKMAPKPQSRCTSTRSAGEAPSENQ------------------SPSKG---PEE 532

Query: 149 AGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLA 208
           A  E ++TN   +  +    +  G  G                       SK     ++ 
Sbjct: 533 ASSEVQDTNEVHVPGDQDEPQTLGKKG-----------------------SKNNISVYMT 569

Query: 209 RWKREAEKKAKVIAGMNAVEENQGPGESQKVEEAS--PPAVQQPTDPASPTVATTPEPVG 266
             +++++  +  +  +++ ++ +         E+   PP        +S + ++  E   
Sbjct: 570 LNQKKSDSSSASVCSIDSTDDLKSSNSECSSSESFDFPPGSMHAPSTSSTSSSSKEEKKL 629

Query: 267 SDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRA--AEG 324
           S++           +    DGR   +G++VW K+ GF WWP RI++  ++ +        
Sbjct: 630 SNSLKMKVFSKNVSKCVTPDGRTICVGDIVWAKIYGFPWWPARILTITVSRKDNGLLVRQ 689

Query: 325 TRWVMWFGDGKFSVVCVEKLMP-LSSFCSAFHQATYNKQPMYRKAIYEVLQVA 376
              + WFG    S + + +L P L +F S F++    ++ +YRKAI E  + A
Sbjct: 690 EARISWFGSPTTSFLALSQLSPFLENFQSRFNK---KRKGLYRKAITEAAKAA 739


>gi|51873049 hypothetical protein LOC8603 [Homo sapiens]
          Length = 1224

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 68/282 (24%), Positives = 108/282 (38%), Gaps = 42/282 (14%)

Query: 18   EREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPS 77
            +R  + ++ EE+EE R KEE Q      +K+    +K+K  P  S D PK   +     +
Sbjct: 901  QRRREEEEDEEEEEDRFKEEFQRLQEL-QKLRAVKKKKKERP--SKDCPKLDMLTRNFQA 957

Query: 78   MAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCC 137
              +    S  + NG LE+  EP+    SP+       P  G GA     +     ++   
Sbjct: 958  ATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFL 1017

Query: 138  TPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYY 197
             PKE  G      + +  +    +      G  +  L   S     P  R T        
Sbjct: 1018 LPKEVNGK-----QHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPT-------- 1064

Query: 198  ISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKV--------------EEAS 243
                K  E  ++ + + E KAKV+  M+  E+ +   E +KV              +E S
Sbjct: 1065 -EPPKATEGQSKPRAQTESKAKVVDLMSITEQKR---EERKVNSNNNNKKQLNHIKDEKS 1120

Query: 244  PPAVQQPTDP------ASPTVATTPEPVGSDAGDKNATKAGD 279
             P   +PT P      +   +A +P+P G +   KN  K GD
Sbjct: 1121 NPTPMEPTSPGEHQQNSKLVLAESPQPKGKN--KKNKKKKGD 1160


>gi|38176300 nestin [Homo sapiens]
          Length = 1621

 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 72/299 (24%), Positives = 111/299 (37%), Gaps = 47/299 (15%)

Query: 7    SGPGDTSSSAAEREEDRKDGEEQEEPRGKEE--RQEPSTTARKVGRPGRKRKHPP----- 59
            S PG   +     +E   +  EQ+   GKEE   Q       +V  PG      P     
Sbjct: 965  SPPG--MAGVENEDEAELNLREQDGFTGKEEVVEQGELNATEEVWIPGEGHPESPEPKEQ 1022

Query: 60   ---VESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQK----- 111
               VE          +      +Q  GA  L     L +  EP  E+    GG +     
Sbjct: 1023 RGLVEGASVKGGAEGLQDPEGQSQQVGAPGLQAPQGLPEAIEPLVEDDVAPGGDQASPEV 1082

Query: 112  --GGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQ------KETNIESMKM 163
              G  PA GE AA   P   + V         G G P    +E+      +E ++E+ ++
Sbjct: 1083 MLGSEPAMGESAAGAEPGPGQGVG--------GLGDPGHLTREEVMEPPLEEESLEAKRV 1134

Query: 164  EGSRGRLR-----GGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKK- 217
            +G  G  +     GGLG E S        L  ++ DP+   +  R+E  A   R AE+  
Sbjct: 1135 QGLEGPRKDLEEAGGLGTEFS-------ELPGKSRDPWEPPREGREESEAEAPRGAEEAF 1187

Query: 218  -AKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKNAT 275
             A+ +    +   +  P  S++ EE  PP +  P+   +P +   P P     G + A+
Sbjct: 1188 PAETLGHTGSDAPSPWPLGSEEAEEDVPPVLVSPSPTYTPILEDAPGPQPQAEGSQEAS 1246


>gi|157738619 smoothelin-like 1 [Homo sapiens]
          Length = 512

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 74/289 (25%), Positives = 106/289 (36%), Gaps = 37/289 (12%)

Query: 7   SGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTP 66
           S  G T S AA+  E    G   EE +G         TA K    G     PP ESG   
Sbjct: 27  SEDGTTVSPAADNPEMSGGGAPAEETKG---------TAGKAINEG-----PPTESGKQE 72

Query: 67  KDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLP 126
           K PA         +D  ++EL   G+     E + E    AGG K  A AE +       
Sbjct: 73  KAPA---------EDGMSAEL--QGEANGLDEVKVESQREAGG-KEDAEAELKKEDGEKE 120

Query: 127 EASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMP 186
           E +   +      +E +  P EA +++     E  K E    +   G   +++ R +P P
Sbjct: 121 ETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEP 180

Query: 187 RLTFQAGDPYYISKR---KRDEWLARWKREAEKKAKVIAGMNAVEENQG---PGESQKVE 240
           + T +  D    S+    +R E     K +A  +        AV E++    P E    E
Sbjct: 181 KATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKE 240

Query: 241 EASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRG 289
           EA   A ++         A   EP     G  +  +  D E E E G G
Sbjct: 241 EAKHGAKEEADAKEEAEDAEEAEP-----GSPSEEQEQDVEKEPEGGAG 284



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 29/114 (25%), Positives = 42/114 (36%), Gaps = 7/114 (6%)

Query: 16  AAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDT-PKDPAVISK 74
           A   EED K   ++E  + KE   EP   A         +K    +     PK+P     
Sbjct: 182 ATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEP----D 237

Query: 75  SPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEA 128
               A+     E     + E   E +P  GSP+  Q+     E EG A  +P +
Sbjct: 238 GKEEAKHGAKEEADAKEEAEDAEEAEP--GSPSEEQEQDVEKEPEGGAGVIPSS 289



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 34/131 (25%), Positives = 48/131 (36%), Gaps = 4/131 (3%)

Query: 17  AEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSP 76
           A+ +E+ +D EE E P    E QE        G  G     P  E  ++P        + 
Sbjct: 250 ADAKEEAEDAEEAE-PGSPSEEQEQDVEKEPEGGAGVIPSSPE-EWPESPTGEGHNLSTD 307

Query: 77  SMAQDSGAS-ELLPNGDLEKRSE-PQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVEN 134
            +  D  AS +  P+      S+ PQ    SP+ G+K     E   +A   P   RA   
Sbjct: 308 GLGPDCVASGQTSPSASESSPSDVPQSPPESPSSGEKKEKAPERRVSAPARPRGPRAQNR 367

Query: 135 GCCTPKEGRGA 145
                K G  A
Sbjct: 368 KAIVDKFGGAA 378


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 68/294 (23%), Positives = 113/294 (38%), Gaps = 36/294 (12%)

Query: 12  TSSSAAEREEDRKDGEEQEEPRGKEERQE------PSTTARKVGRPGRKRKHPPVESGDT 65
           T     E E++ K+ E +EE  G+EE  E       S  A +   P ++ K P  E   +
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526

Query: 66  P-----------KDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPA---GGQK 111
           P           K PA + KSP  A+     E       E +S  + E  SPA     +K
Sbjct: 527 PAEAKSPEKEEAKSPAEV-KSPEKAKSPAKEE--AKSPPEAKSPEKEEAKSPAEVKSPEK 583

Query: 112 GGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKE-----TNIESMKMEGS 166
             +PA+ E  +   P  +++ E      KE   +PAEA    KE       ++S +   S
Sbjct: 584 AKSPAKEEAKS---PAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS 640

Query: 167 RGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNA 226
             +       ++   ++   +   +A  P     +  ++  A+   +AE K+   A    
Sbjct: 641 PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK--AKSPVKAEAKSPEKAKSPV 698

Query: 227 VEENQGPGESQ---KVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKA 277
            EE + P +++   K E  SP   + P    + T      PV  +A      K+
Sbjct: 699 KEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS 752



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 12/151 (7%)

Query: 15  SAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISK 74
           S  + EE  ++ + +E P+  EE + P+T   +  +  +K + P  E+   PK      K
Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA---PKPKVEEKK 878

Query: 75  SPSMAQDSGASELLPNGDLE-KRSEPQPEEGSPAGGQ--KGGAPAEGEGAAETLPEASRA 131
            P++ +   +       + E K+  P PE+ +PA  +  +   P E    A+  P+ ++A
Sbjct: 879 EPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKA 938

Query: 132 VENGCCTPKEGRGAPAEAGKEQKETNIESMK 162
            E      K+      EA  E+K+T  E  K
Sbjct: 939 KEPSKPAEKK------EAAPEKKDTKEEKAK 963



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 37/169 (21%), Positives = 74/169 (43%), Gaps = 19/169 (11%)

Query: 5   PSSGPGDTSSSAAEREEDRKDGEEQEEPRGK------EERQEPSTTARKVGRPGRKRKHP 58
           P     +  + A  + E++KD +++E P+ +      EE++EP+    K  +   K++  
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE-- 895

Query: 59  PVESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEG 118
             E+ D  K P    ++P+        E+  +   ++++E   +E   A  ++   PAE 
Sbjct: 896 --EAEDKKKVPTPEKEAPAKV------EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947

Query: 119 EGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSR 167
           + AA   PE     E     P+E     A+A ++ K  + E  K +  +
Sbjct: 948 KEAA---PEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 993



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 58/277 (20%), Positives = 109/277 (39%), Gaps = 22/277 (7%)

Query: 20  EEDRKDGEEQEEPRGKEERQEPST--TARKVGRPGRKRKHPPVESGDTPKDPAVI---SK 74
           +E+ K   E + P  KEE + P+   +  K   P ++    P E+    K  + +   +K
Sbjct: 555 KEEAKSPPEAKSPE-KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613

Query: 75  SPSMAQDSGASELLPNGDL---EKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRA 131
           SP+ A+     E     ++   EK   P  EE      +K  +P + E  +   PE +++
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP--EKAKSPEKEEAKS---PEKAKS 668

Query: 132 VENGCCTPKEGRGAPAEAGKEQKETNIESMKMEG-SRGRLRGGLGWESSLRQRPMPRLTF 190
                    E   +P +A  +  E     +K E  S  + +  +  E+   ++    +  
Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728

Query: 191 QAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQP 250
           +A  P       ++E  +  K ++ +KAK +      +      ++   EEA  PA + P
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL------DVKSPEAKTPAKEEARSPADKFP 782

Query: 251 TDPASPTVATTPEPVGSDAGDKNATKAGDDE-PEYED 286
               SP       P  + +  K   KA + E P+ E+
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEE 819



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 55/286 (19%), Positives = 103/286 (36%), Gaps = 55/286 (19%)

Query: 16  AAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKS 75
           A  +  ++     +EE +  E+ + P    ++  +   K K P  E   TP+     +KS
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSP---VKEEAKSPEKAKSPVKEEAKTPEK----AKS 738

Query: 76  PSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEG--EGAAETLPEASRAVE 133
           P + +++ + E   + +  K  + +  E      ++  +PA+   E A   + E  ++ E
Sbjct: 739 P-VKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797

Query: 134 NGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAG 193
                 KE   AP +   +++E                     +S +++   P+      
Sbjct: 798 KAKSPLKEDAKAPEKEIPKKEEV--------------------KSPVKEEEKPQEVKVKE 837

Query: 194 DPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTD- 252
            P    K + ++  A  K E +K +K        E  +      KVEE   PAV++P + 
Sbjct: 838 PP---KKAEEEKAPATPKTEEKKDSK------KEEAPKKEAPKPKVEEKKEPAVEKPKES 888

Query: 253 ---------------PASPTVATTPEPVGSDAGDKNATKAGDDEPE 283
                          P     A     V  DA  K  T+    EP+
Sbjct: 889 KVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 69/276 (25%), Positives = 109/276 (39%), Gaps = 34/276 (12%)

Query: 9    PGDTSSSAAEREEDRKDGE-EQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPK 67
            P      A E EE+ ++ E E +E  G+   +     A++          P  E  + P+
Sbjct: 2050 PESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEA----EGEAQPESEGVEAPE 2105

Query: 68   DPAVISKSPSMAQDSGASELLPNGD----LEKRSEPQPE-EGSPAGGQKGGAPAEGEGAA 122
                  K+  +       E  P  +     E   E QPE EG  A   +G A  E EG  
Sbjct: 2106 AEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGI- 2164

Query: 123  ETLPEASRAVENGCCTPK-EGRGAPAEAGKEQKETN-IESMKMEG-SRGRLRGGLGWESS 179
                EA  A E     P+ EG  AP   G+ Q E+  IE+ + EG ++  L G    E+ 
Sbjct: 2165 ----EAQEAEEEA--QPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAE 2218

Query: 180  LRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKV 239
               +P P             +    E  A+ + E E + +      + + + G G+S++ 
Sbjct: 2219 EEAQPEPEGV----------ETPEAEGEAQPESEGETQGEK---KGSPQVSLGDGQSEEA 2265

Query: 240  EEASPPAVQ-QPTDPASPTVATTPEPVGSDAGDKNA 274
             E+S P  + +PT P SP   T  +  GS  G  ++
Sbjct: 2266 SESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSS 2301



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 71/310 (22%), Positives = 116/310 (37%), Gaps = 30/310 (9%)

Query: 5    PSSGPGDTSSSAAEREEDRKDGEEQE-EPRGKEERQEPSTTARKVGRPGRKRKHPPVESG 63
            P S   ++  +  E + + +D E  E E   +E   E    +  V  P  + +    E  
Sbjct: 1956 PESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEE 2015

Query: 64   DTPKDPAVISKSPSM---AQDSGASELLPNGDLEKRSE--PQPEEGSPAGGQKGGAP-AE 117
              P+   V ++  S    AQ+         GD +  S+    PE    A   +G    AE
Sbjct: 2016 AQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAE 2075

Query: 118  GEGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWE 177
            GE   E+    ++  E       EG  AP   G+ QK   IE+ + EG       G+   
Sbjct: 2076 GEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAP 2135

Query: 178  SSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAK-VIAGMNAVE-ENQGPGE 235
             +  +        +A D    ++ + +   A   +EAE++A+  + G+ A E E +   E
Sbjct: 2136 EAEGEAQPESEGVEAQDAEGEAQPESEGIEA---QEAEEEAQPELEGVEAPEAEGEAQPE 2192

Query: 236  SQKVE------EASP-------PAVQQPTDPASPTVATTPEPVG----SDAGDKNATKAG 278
            S+ +E      EA P       P  ++   P  P    TPE  G       G+    K G
Sbjct: 2193 SEGIEAPEAEGEAQPELEGVEAPEAEEEAQP-EPEGVETPEAEGEAQPESEGETQGEKKG 2251

Query: 279  DDEPEYEDGR 288
              +    DG+
Sbjct: 2252 SPQVSLGDGQ 2261



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 33/135 (24%), Positives = 50/135 (37%), Gaps = 11/135 (8%)

Query: 10   GDTSSSAAEREEDRKDGEEQEEPRG---KEERQEPSTTARKVGRPGRKRKHPPVESGDTP 66
            G+    +   E    +GE Q E  G    E  +E       V  P  + +  P   G+T 
Sbjct: 2187 GEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQ 2246

Query: 67   KDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLP 126
             +      SP ++   G SE     +  + S P PE+        GG        ++T P
Sbjct: 2247 GEK---KGSPQVSLGDGQSE-----EASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGP 2298

Query: 127  EASRAVENGCCTPKE 141
             +SRA   G C  K+
Sbjct: 2299 SSSRASSWGNCWQKD 2313



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 68/304 (22%), Positives = 109/304 (35%), Gaps = 35/304 (11%)

Query: 5    PSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGD 64
            P  G  +  + A ERE    + E        E  QE    + +    G+   H     G+
Sbjct: 1758 PKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGE 1817

Query: 65   TP----KDPAVISKSPSMAQDSGASELLPNGD----LEKRSEPQPEEGSPAGGQKGGAPA 116
                  +DP     +  +       E  P  +     E   + Q  EG      +     
Sbjct: 1818 AAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAP 1877

Query: 117  EGEGAAETLPEASRAVENGCCTPKEGRGAPA-EAGKE-QKET-NIESMKMEG-SRGRLRG 172
            E EG A+   E     E       E  GA A EA KE Q ET ++E+++ EG       G
Sbjct: 1878 EAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEG 1937

Query: 173  GLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNA-VEENQ 231
                E+    +     T    +   I  ++ +E       EA+ +++ +  +   VE  +
Sbjct: 1938 AEAQEAEEAAQEAEGQTQPESE--VIESQEAEE-------EAQPESEDVEALEVEVETQE 1988

Query: 232  GPGESQKVEE--ASPPA------VQQPTDPASPTVATTPEPVGSDA----GDKNATKAGD 279
              GE+Q   E   +P A       ++   P S  V   P+  G +A    G+   T+ GD
Sbjct: 1989 AEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTE-GD 2047

Query: 280  DEPE 283
             +PE
Sbjct: 2048 AQPE 2051



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 30/107 (28%), Positives = 41/107 (38%), Gaps = 9/107 (8%)

Query: 20   EEDRKDGEEQEE---PRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSP 76
            EE    G+E  E   P GK  +++      + GR     +  P E  + P +P     S 
Sbjct: 1401 EEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEP----PSH 1456

Query: 77   SMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAE 123
                D  ASE      LE   E  P  G+   GQ+       +GAAE
Sbjct: 1457 LSETDPSASERQSGSQLEPGLEKPP--GATMMGQEHTQAQPTQGAAE 1501



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 62/246 (25%), Positives = 80/246 (32%), Gaps = 39/246 (15%)

Query: 61  ESGDTPKDPAVISKSPS-MAQDSGASELLPNGDLEKRSEPQPEE------GSPAGG---- 109
           ++G     PA I    S     SGA+ L   G+ E R  PQP        G P  G    
Sbjct: 765 DAGSRTCSPAPIPPHTSDSCSKSGAASL---GE-EARDTPQPSSPLVLQVGRPEQGAVGP 820

Query: 110 -------QKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMK 162
                  Q G  PA+ E      PEAS      C TP  GR  P         T      
Sbjct: 821 HRSHCCSQPGTQPAQ-EAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTG----S 875

Query: 163 MEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIA 222
              S  R  GG   E + +  P P      G     S+R      A  +  +E+K     
Sbjct: 876 SHQSTARGPGGSPQEGTRQPGPTP----SPGPNSGASRRSSASQGAGSRGLSEEKTLRSG 931

Query: 223 GMNAVEENQGPGESQKVEEASPPAVQQ------PTDPASPTVATTPEPVGSDAGDKNATK 276
           G    +E         +  +SP AV +      P +P   T     E  G+  G     +
Sbjct: 932 GGPQGQEEASGVSPSSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPE 991

Query: 277 A--GDD 280
              GDD
Sbjct: 992 VDPGDD 997


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 62/284 (21%), Positives = 98/284 (34%), Gaps = 50/284 (17%)

Query: 10  GDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDP 69
           G+      E EE  ++ EE++E  GKEE +       +    G ++K       +  ++ 
Sbjct: 731 GEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790

Query: 70  AVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEAS 129
                      D G  E       E+ +E + EE    G  +GG   EG+G  E   E  
Sbjct: 791 G----------DQGEGE-------EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG 833

Query: 130 RA-VENGCCTPKEGRGAPAEA-GKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMPR 187
               E G    +EG G   E  GK ++E      + EG  G   G               
Sbjct: 834 EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG--------------- 878

Query: 188 LTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAV 247
                         + +E     + E E + +   G    EE +G GE ++ EE      
Sbjct: 879 --------------EEEEGEGEGEEEGEGEGEEEEGEGEGEE-EGEGEGEE-EEGEGKGE 922

Query: 248 QQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFG 291
           ++  +          E  G D   +   + G+ E E E+G G G
Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEG 966



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 40/174 (22%), Positives = 61/174 (35%), Gaps = 15/174 (8%)

Query: 8    GPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKH---PPVESGD 64
            G  +      E EE+  +GE +EE  G+ E +E      + G    + +       E G+
Sbjct: 867  GEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGE 926

Query: 65   TPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAG------GQKGGAPAEG 118
              +      +     +D         G+ E   E    EG   G      G+  G   EG
Sbjct: 927  EGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEG 986

Query: 119  EGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRG 172
            EG  E         E G     EG       G+E++E  +E  ++EG  G   G
Sbjct: 987  EGEGEEEEGEEEGEEEG-----EGEEEGEGEGEEEEEGEVEG-EVEGEEGEGEG 1034



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 53/244 (21%), Positives = 88/244 (36%), Gaps = 20/244 (8%)

Query: 18   EREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGR-----KRKHPPVESGDTPKDPAVI 72
            E EE+  +GE +EE  G+ E +E      + G  G      +      E G+   +    
Sbjct: 894  EGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEG 953

Query: 73   SKSPSMAQDSGASELLPNGDLEK----------RSEPQPEEGSPAGGQKGGAPAEGEGAA 122
                   +  G  E    G+ E+            E + EEG   G ++G    EGEG  
Sbjct: 954  EWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEG 1013

Query: 123  ETLPEASRAVENGCCTPKEGRG-APAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLR 181
            E   E       G    +EG G    E G+E+ E   +  + E +R         E   +
Sbjct: 1014 E---EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQ 1070

Query: 182  QRPMPRLTFQAGDPY-YISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVE 240
            +        Q G+ Y  +SK K      + K   +K      G    + ++ P +S+++ 
Sbjct: 1071 ETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLL 1130

Query: 241  EASP 244
            +  P
Sbjct: 1131 KNGP 1134



 Score = 37.7 bits (86), Expect = 0.049
 Identities = 42/173 (24%), Positives = 58/173 (33%), Gaps = 8/173 (4%)

Query: 8    GPGDTSSSAAEREEDRKDGEEQ-EEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTP 66
            G G+      E EE    GEE+ EE  G+EE +E      +    G   +    E  +  
Sbjct: 840  GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEE 899

Query: 67   KDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAG--GQKGGAPAEGEGAAET 124
             +     +     ++            E   E + EEG   G  G+  G   EGE   E 
Sbjct: 900  GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEE 959

Query: 125  LPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWE 177
                    E G     EG G   E   E++E   E  + EG       G G E
Sbjct: 960  EEGEGEGEEEG-----EGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007



 Score = 37.4 bits (85), Expect = 0.064
 Identities = 67/315 (21%), Positives = 107/315 (33%), Gaps = 40/315 (12%)

Query: 9   PGDTSSSAAERE---EDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDT 65
           P  T  + ++ E    + K+G E  +  G EE++  +         GRK K   +    T
Sbjct: 572 PATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLT 631

Query: 66  PKDPAVISKSPSMAQDSGASELLPNGDLEKRSEP----QPEEGSPAGGQKGGAPAE--GE 119
            K      K+ S+ +     E   +G  E+ S      Q EE       KG    E  GE
Sbjct: 632 DKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE 691

Query: 120 GAAETL-----------------------PEASRAVENGCCTPKEGRGAPAEAGKEQKET 156
           G  E                          E ++ +E G    + G G   E  +E++E 
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEG-GEEEHGEGEEEEGDREEEEE 750

Query: 157 NIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEK 216
                K EG    + G    E   R++       + G+         +E       E E+
Sbjct: 751 KEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEE 810

Query: 217 KAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATK 276
             +V  G   VEE +G  E ++ E        +  +          E  G + G++    
Sbjct: 811 GGEVEGG--EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE---- 864

Query: 277 AGDDEPEYEDGRGFG 291
            G+ E E E+G G G
Sbjct: 865 -GEGEEEGEEGEGEG 878



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 15/49 (30%), Positives = 24/49 (48%)

Query: 8    GPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRK 56
            G G+      E EE  K+GE +E  R +EE +E     ++ G    +R+
Sbjct: 1032 GEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQ 1080


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 45/153 (29%), Positives = 60/153 (39%), Gaps = 13/153 (8%)

Query: 26  GEEQEEPRGKEERQEPSTTA--RKVGRPGRKRKHPPVES-GDTPKDPAVISKSPSMAQDS 82
           G     P G E  + PS T   R  G  G +    P E+ G  P  PA    + S ++  
Sbjct: 523 GPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 582

Query: 83  GASELLPNGD--LEKRSE-PQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTP 139
           G S   P  D   E  SE P P    PAG +   +P+E  G     P      E+   TP
Sbjct: 583 GPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 642

Query: 140 KEG-----RGAPAEAGK--EQKETNIESMKMEG 165
                   R  PA+AG+  E ++  +ES    G
Sbjct: 643 GPSPAGPTRDEPAKAGEAAELQDAEVESSAKSG 675



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 40/130 (30%), Positives = 52/130 (40%), Gaps = 10/130 (7%)

Query: 34  GKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGASELLPNGD- 92
           G EE  E   T  K G PG   + P    G +P  PA    + S ++  G     P GD 
Sbjct: 499 GVEEDTE-GRTGPKEGTPGSPSETP----GPSPAGPAGDEPAESPSETPGPRPAGPAGDE 553

Query: 93  -LEKRSE-PQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAG 150
             E  SE P P    PAG +   +P+E  G +   P      E+   TP      P  AG
Sbjct: 554 PAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGP--AG 611

Query: 151 KEQKETNIES 160
            E  E+  E+
Sbjct: 612 DEPAESPSET 621



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 70/298 (23%), Positives = 100/298 (33%), Gaps = 36/298 (12%)

Query: 6   SSGPGDTSSSAAEREEDRKDGEEQEEPRGKE------ERQEPSTTARKVGRPGR--KRKH 57
           S G G        R  + +D    E  +G E      +R EP +      R     +R+ 
Sbjct: 335 SKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQ 394

Query: 58  PPVESGDTPKDPAVISKSPSMAQDSGASE-LLPNGDLEKRSEPQPEEGSPAGGQKGGAPA 116
           PP E G  P+  + + K     +    S+  L  G  E   +   E   P     G   A
Sbjct: 395 PPTEPG--PQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVA 452

Query: 117 EGEGAAETLPEA---SRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGG 173
           +       + E    S AV +G        G+PA +G   K  + E+   E + GR    
Sbjct: 453 DKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSG-HPKAGHSENGVEEDTEGRTGPK 511

Query: 174 LGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGP 233
            G   S  + P P     AGD    S              +E      AG    E  + P
Sbjct: 512 EGTPGSPSETPGPSPAGPAGDEPAESP-------------SETPGPRPAGPAGDEPAESP 558

Query: 234 GESQKVEEASPPAVQQPTDPA-----SPTVATTPEPVGSDA---GDKNATKAGDDEPE 283
            E+     A P   +    P+     SP   T  EP  S +   G + A  AGD+  E
Sbjct: 559 SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAE 616



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 35/121 (28%), Positives = 45/121 (37%), Gaps = 8/121 (6%)

Query: 77  SMAQDSGASELLPNGD--LEKRSE-PQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVE 133
           S ++  G S   P GD   E  SE P P    PAG +   +P+E  G     P      E
Sbjct: 517 SPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 576

Query: 134 NGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAG 193
           +   TP      P+ AG  + E      +  G R     G     S  + P PR    AG
Sbjct: 577 SPSETP-----GPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAG 631

Query: 194 D 194
           D
Sbjct: 632 D 632



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 36/140 (25%), Positives = 47/140 (33%), Gaps = 11/140 (7%)

Query: 5   PSSGPGDTSSSAAEREE----DRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60
           PS  PG   +  A  E         G     P G E  + PS T      P    +  P 
Sbjct: 538 PSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP--SPAGPTRDEPA 595

Query: 61  ES-----GDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAP 115
           ES     G  P  PA    + S ++  G     P GD    S  +    SPAG  +    
Sbjct: 596 ESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655

Query: 116 AEGEGAAETLPEASRAVENG 135
             GE A     E   + ++G
Sbjct: 656 KAGEAAELQDAEVESSAKSG 675


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 38/168 (22%), Positives = 59/168 (35%), Gaps = 11/168 (6%)

Query: 426 EEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQ 485
           E+  N   E    M   P+      P P     K   + P+ +     +T E L      
Sbjct: 105 EDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKT-ENLKKRGED 163

Query: 486 KCRNIEDICISCGSL------NVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTI 539
               I   C +CG        +    HP     +C+NC   ++      D DG    C  
Sbjct: 164 GLHGIVS-CTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRW 222

Query: 540 CCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKE-DPWNCYMC 586
           C  G  ++ C  + C   FC +C+   +G       + E + W CY+C
Sbjct: 223 CAEGGNLICC--DFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYIC 268



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 47/220 (21%), Positives = 85/220 (38%), Gaps = 16/220 (7%)

Query: 9    PGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKD 68
            PGD  +      E   D EE ++PR +        T    G  G ++K  P E     K+
Sbjct: 1311 PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSD-GESGEEKKTKPKEH----KE 1365

Query: 69   PAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEA 128
                ++    ++DS  S+   +G  E+ SE + E+       K     E + + +   + 
Sbjct: 1366 VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1425

Query: 129  SR-------AVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLR 181
             R       + EN   + +E      E  +E++E   E  + + S+   +G       L+
Sbjct: 1426 RRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILK 1485

Query: 182  QRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVI 221
               +   T  A       + +R + +A  +RE EK  +VI
Sbjct: 1486 DDKLRTETQNA----LKEEEERRKRIAEREREREKLREVI 1521


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 36/150 (24%), Positives = 58/150 (38%), Gaps = 16/150 (10%)

Query: 451 PPPAKKPRKSTAEKPKVKEIIDE-RTRERLVYEVRQKCRNIED------ICISCGSL--- 500
           P    K  +S  EKP   E ++E  + E    ++  +    ED       C +CG     
Sbjct: 83  PSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKEDGLHGIVSCTACGQQVNH 142

Query: 501 ---NVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRC 557
              +    HP     +C+NC   ++      D DG    C  C  G  ++ C  + C   
Sbjct: 143 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICC--DFCHNA 200

Query: 558 FCVECVDLLVGPGAAQAAIKE-DPWNCYMC 586
           FC +C+   +G       + E + W CY+C
Sbjct: 201 FCKKCILRNLGRKELSTIMDENNQWYCYIC 230



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 47/220 (21%), Positives = 85/220 (38%), Gaps = 16/220 (7%)

Query: 9    PGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKD 68
            PGD  +      E   D EE ++PR +        T    G  G ++K  P E     K+
Sbjct: 1273 PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSD-GESGEEKKTKPKEH----KE 1327

Query: 69   PAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEA 128
                ++    ++DS  S+   +G  E+ SE + E+       K     E + + +   + 
Sbjct: 1328 VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1387

Query: 129  SR-------AVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLR 181
             R       + EN   + +E      E  +E++E   E  + + S+   +G       L+
Sbjct: 1388 RRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILK 1447

Query: 182  QRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVI 221
               +   T  A       + +R + +A  +RE EK  +VI
Sbjct: 1448 DDKLRTETQNA----LKEEEERRKRIAEREREREKLREVI 1483


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 71/309 (22%), Positives = 116/309 (37%), Gaps = 52/309 (16%)

Query: 2   PAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVE 61
           P M S+G  D+SS       D  D E   +P  K  + + S+ + K   P RK    P +
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVE--GKPSVKPAQVKASSVSTKES-PARKAAPAPGK 244

Query: 62  SGD-TPK------DPAVISKSP-----SMAQDSGASELLPNGD----------LEKRSEP 99
            GD TP+       PA  +K P     S  + S + E  P G           L+ R+  
Sbjct: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304

Query: 100 QPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIE 159
            P +G+P  G     P +  GA  +  +A +  E       +   +  E+   ++ET   
Sbjct: 305 APAKGTPGKGATPAPPGKA-GAVASQTKAGKPEE-------DSESSSEESSDSEEETPAA 356

Query: 160 SMKMEGSRGRLRGGLGWESS-LRQRPM-------PRLTFQAGDPYYISKRKRDEWLARWK 211
              ++         +G  S+  ++ P        P  T  A       KR+ D   +  +
Sbjct: 357 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEE 416

Query: 212 REAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGD 271
            ++E++A   A        +  G++ +V  AS PA + P   A+P     P   G  A  
Sbjct: 417 SDSEEEAPAQA--------KPSGKAPQVRAASAPAKESPRKGAAP---APPRKTGPAAAQ 465

Query: 272 KNATKAGDD 280
               K  +D
Sbjct: 466 VQVGKQEED 474



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 43/174 (24%), Positives = 66/174 (37%), Gaps = 15/174 (8%)

Query: 2   PAMPS-SGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQ-EPSTTARKVGRPGRKRKHPP 59
           PA P  +GP    + A +REED +   E+ +   +   Q +PS  A +V       K  P
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447

Query: 60  VESGDTPKDPAVISKSPSMAQ------DSGASELLPNGDLEKRSEPQPEEGSPAGGQKGG 113
              G  P  P     + +  Q      DS +S    + D E  +     +  P G     
Sbjct: 448 -RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506

Query: 114 APAEGEGAAETLPEASRAVENGCCTPKEGRGAP-AEAGKEQKETNIESMKMEGS 166
            PA   G    L + +  V  G    K G   P A+ GK ++++   S +   S
Sbjct: 507 KPASTMGMG-PLGKGAGPVPPG----KVGPATPSAQVGKWEEDSESSSEESSDS 555


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 71/309 (22%), Positives = 116/309 (37%), Gaps = 52/309 (16%)

Query: 2   PAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVE 61
           P M S+G  D+SS       D  D E   +P  K  + + S+ + K   P RK    P +
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVE--GKPSVKPAQVKASSVSTKES-PARKAAPAPGK 244

Query: 62  SGD-TPK------DPAVISKSP-----SMAQDSGASELLPNGD----------LEKRSEP 99
            GD TP+       PA  +K P     S  + S + E  P G           L+ R+  
Sbjct: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304

Query: 100 QPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIE 159
            P +G+P  G     P +  GA  +  +A +  E       +   +  E+   ++ET   
Sbjct: 305 APAKGTPGKGATPAPPGKA-GAVASQTKAGKPEE-------DSESSSEESSDSEEETPAA 356

Query: 160 SMKMEGSRGRLRGGLGWESS-LRQRPM-------PRLTFQAGDPYYISKRKRDEWLARWK 211
              ++         +G  S+  ++ P        P  T  A       KR+ D   +  +
Sbjct: 357 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEE 416

Query: 212 REAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGD 271
            ++E++A   A        +  G++ +V  AS PA + P   A+P     P   G  A  
Sbjct: 417 SDSEEEAPAQA--------KPSGKAPQVRAASAPAKESPRKGAAP---APPRKTGPAAAQ 465

Query: 272 KNATKAGDD 280
               K  +D
Sbjct: 466 VQVGKQEED 474



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 43/174 (24%), Positives = 66/174 (37%), Gaps = 15/174 (8%)

Query: 2   PAMPS-SGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQ-EPSTTARKVGRPGRKRKHPP 59
           PA P  +GP    + A +REED +   E+ +   +   Q +PS  A +V       K  P
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447

Query: 60  VESGDTPKDPAVISKSPSMAQ------DSGASELLPNGDLEKRSEPQPEEGSPAGGQKGG 113
              G  P  P     + +  Q      DS +S    + D E  +     +  P G     
Sbjct: 448 -RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506

Query: 114 APAEGEGAAETLPEASRAVENGCCTPKEGRGAP-AEAGKEQKETNIESMKMEGS 166
            PA   G    L + +  V  G    K G   P A+ GK ++++   S +   S
Sbjct: 507 KPASTMGMG-PLGKGAGPVPPG----KVGPATPSAQVGKWEEDSESSSEESSDS 555


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 71/309 (22%), Positives = 116/309 (37%), Gaps = 52/309 (16%)

Query: 2   PAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVE 61
           P M S+G  D+SS       D  D E   +P  K  + + S+ + K   P RK    P +
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVE--GKPSVKPAQVKASSVSTKES-PARKAAPAPGK 244

Query: 62  SGD-TPK------DPAVISKSP-----SMAQDSGASELLPNGD----------LEKRSEP 99
            GD TP+       PA  +K P     S  + S + E  P G           L+ R+  
Sbjct: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304

Query: 100 QPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIE 159
            P +G+P  G     P +  GA  +  +A +  E       +   +  E+   ++ET   
Sbjct: 305 APAKGTPGKGATPAPPGKA-GAVASQTKAGKPEE-------DSESSSEESSDSEEETPAA 356

Query: 160 SMKMEGSRGRLRGGLGWESS-LRQRPM-------PRLTFQAGDPYYISKRKRDEWLARWK 211
              ++         +G  S+  ++ P        P  T  A       KR+ D   +  +
Sbjct: 357 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEE 416

Query: 212 REAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGD 271
            ++E++A   A        +  G++ +V  AS PA + P   A+P     P   G  A  
Sbjct: 417 SDSEEEAPAQA--------KPSGKAPQVRAASAPAKESPRKGAAP---APPRKTGPAAAQ 465

Query: 272 KNATKAGDD 280
               K  +D
Sbjct: 466 VQVGKQEED 474



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 43/174 (24%), Positives = 66/174 (37%), Gaps = 15/174 (8%)

Query: 2   PAMPS-SGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQ-EPSTTARKVGRPGRKRKHPP 59
           PA P  +GP    + A +REED +   E+ +   +   Q +PS  A +V       K  P
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447

Query: 60  VESGDTPKDPAVISKSPSMAQ------DSGASELLPNGDLEKRSEPQPEEGSPAGGQKGG 113
              G  P  P     + +  Q      DS +S    + D E  +     +  P G     
Sbjct: 448 -RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506

Query: 114 APAEGEGAAETLPEASRAVENGCCTPKEGRGAP-AEAGKEQKETNIESMKMEGS 166
            PA   G    L + +  V  G    K G   P A+ GK ++++   S +   S
Sbjct: 507 KPASTMGMG-PLGKGAGPVPPG----KVGPATPSAQVGKWEEDSESSSEESSDS 555


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 71/309 (22%), Positives = 116/309 (37%), Gaps = 52/309 (16%)

Query: 2   PAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVE 61
           P M S+G  D+SS       D  D E   +P  K  + + S+ + K   P RK    P +
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVE--GKPSVKPAQVKASSVSTKES-PARKAAPAPGK 244

Query: 62  SGD-TPK------DPAVISKSP-----SMAQDSGASELLPNGD----------LEKRSEP 99
            GD TP+       PA  +K P     S  + S + E  P G           L+ R+  
Sbjct: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304

Query: 100 QPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIE 159
            P +G+P  G     P +  GA  +  +A +  E       +   +  E+   ++ET   
Sbjct: 305 APAKGTPGKGATPAPPGKA-GAVASQTKAGKPEE-------DSESSSEESSDSEEETPAA 356

Query: 160 SMKMEGSRGRLRGGLGWESS-LRQRPM-------PRLTFQAGDPYYISKRKRDEWLARWK 211
              ++         +G  S+  ++ P        P  T  A       KR+ D   +  +
Sbjct: 357 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEE 416

Query: 212 REAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGD 271
            ++E++A   A        +  G++ +V  AS PA + P   A+P     P   G  A  
Sbjct: 417 SDSEEEAPAQA--------KPSGKAPQVRAASAPAKESPRKGAAP---APPRKTGPAAAQ 465

Query: 272 KNATKAGDD 280
               K  +D
Sbjct: 466 VQVGKQEED 474



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 43/174 (24%), Positives = 66/174 (37%), Gaps = 15/174 (8%)

Query: 2   PAMPS-SGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQ-EPSTTARKVGRPGRKRKHPP 59
           PA P  +GP    + A +REED +   E+ +   +   Q +PS  A +V       K  P
Sbjct: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447

Query: 60  VESGDTPKDPAVISKSPSMAQ------DSGASELLPNGDLEKRSEPQPEEGSPAGGQKGG 113
              G  P  P     + +  Q      DS +S    + D E  +     +  P G     
Sbjct: 448 -RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506

Query: 114 APAEGEGAAETLPEASRAVENGCCTPKEGRGAP-AEAGKEQKETNIESMKMEGS 166
            PA   G    L + +  V  G    K G   P A+ GK ++++   S +   S
Sbjct: 507 KPASTMGMG-PLGKGAGPVPPG----KVGPATPSAQVGKWEEDSESSSEESSDS 555


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 40/136 (29%), Positives = 60/136 (44%), Gaps = 11/136 (8%)

Query: 11  DTSSSAAEREEDRKDGEEQEE-PRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTP--- 66
           D SSS+ E  E +    +QEE P+G +E+ + S  + +   P   ++    +   TP   
Sbjct: 276 DGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEK 335

Query: 67  ---KDPAVISKSPSMAQ-DSGASELL--PNGDLEKRSEPQPEEGSPAGGQKGGAP-AEGE 119
              KD +  S S   +  DS AS  L         + E +P  GS  G  + G P AEG 
Sbjct: 336 KRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGG 395

Query: 120 GAAETLPEASRAVENG 135
             + TL  A+  +E G
Sbjct: 396 STSSTLRAAASKLEQG 411



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 31/154 (20%), Positives = 58/154 (37%), Gaps = 28/154 (18%)

Query: 19  REEDRKDGEEQEEPRGKEERQE----------------PSTTARKVGRPGRKRKHPPVES 62
           +++D+ + EE++E RG+ +  E                   +  + GR  + +K  P+  
Sbjct: 183 KDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAK 242

Query: 63  GDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAA 122
           G          K      D  A E   +GD E +      +GS +  ++     E +  A
Sbjct: 243 GGR-------KKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEE----PESKAKA 291

Query: 123 ETLPEASRAVENGCCTPKEG-RGAPAEAGKEQKE 155
               E  + V+    + +E     P E  KE++E
Sbjct: 292 PQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEE 325


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 10/122 (8%)

Query: 3   AMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVES 62
           A    GPG       + EED ++ EE EE   ++E +EP   A+ +G+  +    PP  +
Sbjct: 65  AASGGGPG------GDEEEDEEEEEEDEEALLEDEDEEP-PPAQALGQAAQPPPEPPEAA 117

Query: 63  G-DTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGA 121
             +   +P    K       SG         L KR E +PEE S  G +  G+   G+ A
Sbjct: 118 AMEAAAEPDASEKPAEATAGSGGVNGGEEQGLGKREEDEPEERS--GDETPGSEVPGDKA 175

Query: 122 AE 123
           AE
Sbjct: 176 AE 177


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 34/130 (26%), Positives = 49/130 (37%), Gaps = 2/130 (1%)

Query: 25  DGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGA 84
           D EE  E  G   RQ+PS  + ++ RP      P   +G T    + +  + S     GA
Sbjct: 27  DEEEDAEEEGAGGRQDPSRRSIRL-RP-LPSPSPSAAAGGTESRSSALGAADSEGPARGA 84

Query: 85  SELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRG 144
            +   NGD  +        GS  GG  G       G      E  R +  G  +P E R 
Sbjct: 85  GKSSTNGDCRRFRGSLASLGSRGGGSGGTGSGSSHGHLHDSAEERRLIAEGDASPGEDRT 144

Query: 145 APAEAGKEQK 154
            P  A + ++
Sbjct: 145 PPGLAAEPER 154


>gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 235

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 49/158 (31%), Positives = 62/158 (39%), Gaps = 19/158 (12%)

Query: 33  RGKEERQEPSTTARKVGRPGRKR--KHPPVESGDTPKDPAVISKSPSMAQDSGASELLPN 90
           RG+ ER+     A K G PGR+R  K PP     T   P    + PS  QD+G +     
Sbjct: 77  RGRAERRSMQAAAAKAGSPGRRRVGKGPPSRESWTRSAP---QRCPS--QDAGRA----- 126

Query: 91  GDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAE---TLPEASRAVENGCCTPKE--GRGA 145
           G    RS PQ   G  A     GA   G G  E     P A+ A   G  + K+   RG 
Sbjct: 127 GSRVCRSRPQSRGGQKAAA--SGAKRRGVGGKEPRRQKPAAAGAKSRGGKSHKKPRRRGQ 184

Query: 146 PAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQR 183
            A   K       +  K   +  + RGG G +   R R
Sbjct: 185 KAAPAKNSGGGGNKPQKAAAAGAKNRGGGGGKKPRRGR 222


>gi|11560152 zinc finger protein 335 [Homo sapiens]
          Length = 1342

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 17/151 (11%)

Query: 20  EEDRKDGEEQEEPRGKEER-QEPS-TTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPS 77
           EED      ++EPRG++ R Q P+ +T R   RPGR RK P +E  D P     +   P 
Sbjct: 318 EEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLEISDLPDG---VEGEPL 374

Query: 78  MAQDSGASELLPNGDLEKRSEPQPEEGSPAGG------QKGGAPAEGEGAAETLPEASRA 131
           ++  SG S   P  D E  S   P      G       + G + ++ E AA + P+    
Sbjct: 375 VSSQSGQSPPEPQ-DPEAPSSSGPGHLVAMGKVSRTPVEAGVSQSDAENAAPSCPD---- 429

Query: 132 VENGCCTPKEGRGAPAEAGKEQKETNIESMK 162
            E+     + GR +    GK+ ++   +S K
Sbjct: 430 -EHDTLPRRRGRPSRRFLGKKYRKYYYKSPK 459


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,322,687
Number of Sequences: 37866
Number of extensions: 2334795
Number of successful extensions: 17425
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 558
Number of HSP's that attempted gapping in prelim test: 14849
Number of HSP's gapped (non-prelim): 2723
length of query: 912
length of database: 18,247,518
effective HSP length: 111
effective length of query: 801
effective length of database: 14,044,392
effective search space: 11249557992
effective search space used: 11249557992
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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