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Search of human proteins with 28212222
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28212222 WFIKKN2 protein [Homo sapiens]
(576 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28212222 WFIKKN2 protein [Homo sapiens] 1229 0.0
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 634 0.0
gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo sap... 99 1e-20
gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo sapi... 80 5e-15
gi|73760409 tissue factor pathway inhibitor isoform b precursor ... 79 1e-14
gi|5454114 tissue factor pathway inhibitor isoform a precursor [... 79 1e-14
gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo sap... 73 6e-13
gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens] 70 5e-12
gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ... 68 2e-11
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ... 68 2e-11
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 68 3e-11
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP... 66 1e-10
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP... 66 1e-10
gi|145309328 papilin [Homo sapiens] 65 2e-10
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa... 61 3e-09
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa... 61 3e-09
gi|109150416 peroxidasin [Homo sapiens] 60 4e-09
gi|144226847 obscurin-like 1 [Homo sapiens] 59 1e-08
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 59 1e-08
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 59 1e-08
gi|41406055 amyloid beta A4 protein isoform b precursor [Homo sa... 59 2e-08
gi|4502167 amyloid beta A4 protein isoform a precursor [Homo sap... 59 2e-08
gi|209915573 amyloid beta A4 protein isoform f precursor [Homo s... 59 2e-08
gi|119220552 sidekick 1 [Homo sapiens] 58 2e-08
gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2 ... 58 2e-08
gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2 p... 58 2e-08
gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1 ... 58 2e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 57 4e-08
gi|110349717 titin isoform novex-2 [Homo sapiens] 57 4e-08
gi|110349713 titin isoform novex-1 [Homo sapiens] 57 4e-08
>gi|28212222 WFIKKN2 protein [Homo sapiens]
Length = 576
Score = 1229 bits (3179), Expect = 0.0
Identities = 576/576 (100%), Positives = 576/576 (100%)
Query: 1 MWAPRCRRFWSRWEQVAALLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQS 60
MWAPRCRRFWSRWEQVAALLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQS
Sbjct: 1 MWAPRCRRFWSRWEQVAALLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQS 60
Query: 61 TCRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQG 120
TCRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQG
Sbjct: 61 TCRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQG 120
Query: 121 SECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFT 180
SECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFT
Sbjct: 121 SECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFT 180
Query: 181 WPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPE 240
WPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPE
Sbjct: 181 WPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPE 240
Query: 241 ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADF 300
ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADF
Sbjct: 241 ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADF 300
Query: 301 PLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGH 360
PLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGH
Sbjct: 301 PLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGH 360
Query: 361 CHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCE 420
CHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCE
Sbjct: 361 CHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCE 420
Query: 421 GNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDSGR 480
GNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDSGR
Sbjct: 421 GNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDSGR 480
Query: 481 ALVTVDEVLKDEKMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVDGGMAML 540
ALVTVDEVLKDEKMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVDGGMAML
Sbjct: 481 ALVTVDEVLKDEKMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVDGGMAML 540
Query: 541 RPDSFVGASSARRVRKLREVMHKKTCDVLKEFLGLH 576
RPDSFVGASSARRVRKLREVMHKKTCDVLKEFLGLH
Sbjct: 541 RPDSFVGASSARRVRKLREVMHKKTCDVLKEFLGLH 576
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 634 bits (1634), Expect = 0.0
Identities = 311/560 (55%), Positives = 388/560 (69%), Gaps = 26/560 (4%)
Query: 19 LLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQSTCRRECETDQECETYEKC 78
LL LLLLL + + LP + SH G+CPN ++PNLWVDAQSTC REC DQ+C EKC
Sbjct: 7 LLPLLLLLRLTSGAGLLPGLG-SHPGVCPNQLSPNLWVDAQSTCERECSRDQDCAAAEKC 65
Query: 79 CPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGSECDIWDGQPVCKCKDRC 138
C NVCG SCVAAR+ P A+C+ F+C QQGS+CDIWDGQPVC+C+DRC
Sbjct: 66 CINVCGLHSCVAARFPG-----SPAAPTTAASCEGFVCPQQGSDCDIWDGQPVCRCRDRC 120
Query: 139 EKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFTWPNTSPPPPETTMHPTTA 198
EKEPSFTCASDGLTYYNRCYMDAEAC +G+ L +V C++ +WP +SP PPETT PT
Sbjct: 121 EKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPG 180
Query: 199 SPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN 258
+ P PAL ++P Q+V +G T S CDV GRP P +TWEKQ REN++MRP+
Sbjct: 181 AAPVP------PALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPD 234
Query: 259 HVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVVRGHQAAATSESSP 318
+ GNVVVT+I QLV+YNA+ +DAG+YTCTARN AG+LRADFPLSVV+ A + S P
Sbjct: 235 QMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIP 294
Query: 319 NGTAFPAAECLKPPDSEDC----GEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEAC 374
AECL PD + C WH+D Q C+TF C FETYEAC
Sbjct: 295 -----APAECL--PDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEAC 347
Query: 375 MLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEE 434
AC GP AC LPA+QGPC+ + PRWAY+ QC FVYGGCEGNGNNF SRE+CE+
Sbjct: 348 QQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCED 407
Query: 435 SCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDS--GRALVTVDEVLKDE 492
+CP PR CRAC+ R KL S CRSDF I+GR++E+ EEP++ G A V +++VLKD+
Sbjct: 408 ACPVPR-TPPCRACRLRSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALEDVLKDD 466
Query: 493 KMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVDGGMAMLRPDSFVGASSAR 552
KMGLKFLG + LEVTL +DWACPCPN+T + PL+IMGEV G+A+L S+V A+S +
Sbjct: 467 KMGLKFLGTKYLEVTLSGMDWACPCPNMTAGDGPLVIMGEVRDGVAVLDAGSYVRAASEK 526
Query: 553 RVRKLREVMHKKTCDVLKEF 572
RV+K+ E++ K+ C++L F
Sbjct: 527 RVKKILELLEKQACELLNRF 546
>gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo
sapiens]
Length = 352
Score = 99.0 bits (245), Expect = 1e-20
Identities = 50/146 (34%), Positives = 76/146 (52%), Gaps = 9/146 (6%)
Query: 301 PLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQ-------TRWHFDAQANNC 353
P+ + R +A E +G E K DS G +R+ ++ + C
Sbjct: 197 PILIPRVRRAVLPQEEEGSGGGQLVTEVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMAC 256
Query: 354 LTFTFGHCHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQS 413
TF +G C N N+F T + C+ C + +AAC+LP ++GPC+A+ WA+++ G+C
Sbjct: 257 ETFQYGGCMGNGNNFVTEKECLQTCRT--VAACNLPIVRGPCRAFIQLWAFDAVKGKCVL 314
Query: 414 FVYGGCEGNGNNFESREACEESCPFP 439
F YGGC+GNGN F S + C E C P
Sbjct: 315 FPYGGCQGNGNKFYSEKECREYCGVP 340
>gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo
sapiens]
Length = 252
Score = 80.1 bits (196), Expect = 5e-15
Identities = 53/193 (27%), Positives = 80/193 (41%), Gaps = 48/193 (24%)
Query: 337 CGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMS------GPLAA----- 385
C RW ++ +C F +G C N N++ T E C+ C + G LA
Sbjct: 47 CRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAA 106
Query: 386 --------------------------CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGC 419
C+ A+ GPC+A PRW ++ + C +F+YGGC
Sbjct: 107 DSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGC 166
Query: 420 EGNGNNFESREAC-------EESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSEL 472
GN N++ S EAC +E+ P P G++ ++ F + V L RV+
Sbjct: 167 RGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARR 226
Query: 473 TEEPDSGRALVTV 485
+E RAL TV
Sbjct: 227 NQE----RALRTV 235
Score = 65.1 bits (157), Expect = 2e-10
Identities = 30/67 (44%), Positives = 39/67 (58%), Gaps = 9/67 (13%)
Query: 379 MSGPLAA---------CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESR 429
+SG LAA C + + G C+A PRW YN G CQ FVYGGC+GN NN+ ++
Sbjct: 22 LSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTK 81
Query: 430 EACEESC 436
E C + C
Sbjct: 82 EECLKKC 88
>gi|73760409 tissue factor pathway inhibitor isoform b precursor
[Homo sapiens]
Length = 251
Score = 78.6 bits (192), Expect = 1e-14
Identities = 42/122 (34%), Positives = 52/122 (42%), Gaps = 13/122 (10%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAA-- 385
C D C R+ F+ C F +G C N N FE+ E C C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 386 -----------CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEE 434
C L G C+ Y R+ YN+QT QC+ F YGGC GN NNFE+ E C+
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 435 SC 436
C
Sbjct: 174 IC 175
Score = 67.8 bits (164), Expect = 3e-11
Identities = 31/77 (40%), Positives = 42/77 (54%)
Query: 386 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRC 445
C+ A GPCKA R+ +N T QC+ F+YGGCEGN N FES E C++ C N+
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 446 RACKPRQKLVTSFCRSD 462
+ ++K F D
Sbjct: 114 KTTLQQEKPDFCFLEED 130
Score = 43.9 bits (102), Expect = 4e-04
Identities = 20/55 (36%), Positives = 26/55 (47%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGP 382
C D C TR+ ++ Q C F +G C N+N+FET E C C GP
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGP 179
>gi|5454114 tissue factor pathway inhibitor isoform a precursor
[Homo sapiens]
Length = 304
Score = 78.6 bits (192), Expect = 1e-14
Identities = 42/122 (34%), Positives = 52/122 (42%), Gaps = 13/122 (10%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAA-- 385
C D C R+ F+ C F +G C N N FE+ E C C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 386 -----------CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEE 434
C L G C+ Y R+ YN+QT QC+ F YGGC GN NNFE+ E C+
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 435 SC 436
C
Sbjct: 174 IC 175
Score = 76.6 bits (187), Expect = 6e-14
Identities = 44/143 (30%), Positives = 58/143 (40%), Gaps = 34/143 (23%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAA-- 385
C D C TR+ ++ Q C F +G C N+N+FET E C C GP
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQV 184
Query: 386 --------------------------------CSLPALQGPCKAYAPRWAYNSQTGQCQS 413
C PA +G C+A R+ YNS G+C+
Sbjct: 185 DNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRP 244
Query: 414 FVYGGCEGNGNNFESREACEESC 436
F Y GC GN NNF S++ C +C
Sbjct: 245 FKYSGCGGNENNFTSKQECLRAC 267
Score = 67.8 bits (164), Expect = 3e-11
Identities = 31/77 (40%), Positives = 42/77 (54%)
Query: 386 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRC 445
C+ A GPCKA R+ +N T QC+ F+YGGCEGN N FES E C++ C N+
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 446 RACKPRQKLVTSFCRSD 462
+ ++K F D
Sbjct: 114 KTTLQQEKPDFCFLEED 130
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Query: 311 AATSESSPNGTAFPA-------AECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHR 363
A + +P T P+ + CL P D C + R+++++ C F + C
Sbjct: 193 AVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGG 252
Query: 364 NLNHFETYEACMLACMSG 381
N N+F + + C+ AC G
Sbjct: 253 NENNFTSKQECLRACKKG 270
>gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo
sapiens]
Length = 89
Score = 73.2 bits (178), Expect = 6e-13
Identities = 27/53 (50%), Positives = 36/53 (67%)
Query: 386 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPF 438
C+ P +GPC+ Y RW +N +TG+C+ F YGGC GN NNF +E CE+ C F
Sbjct: 36 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCKF 88
Score = 39.3 bits (90), Expect = 0.010
Identities = 17/51 (33%), Positives = 22/51 (43%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378
C P + C TRW F+ + C F +G C N N+F E C C
Sbjct: 36 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 86
>gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens]
Length = 235
Score = 70.1 bits (170), Expect = 5e-12
Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 3/105 (2%)
Query: 335 EDCGEEQTRWHFDAQANNCLTFTFGHCHRNL--NHFETYEACMLACMSGPLAA-CSLPAL 391
+ C ++ F+ + C F G CHRN N F CM C + + C P
Sbjct: 104 DQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKD 163
Query: 392 QGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
+G C A R+ +N + C +F Y GC GN NNF SRE C+ +C
Sbjct: 164 EGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 65.1 bits (157), Expect = 2e-10
Identities = 26/51 (50%), Positives = 35/51 (68%)
Query: 386 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
C LP GPC+A R+ Y+ T C+ F+YGGCEGN NNF + EAC+++C
Sbjct: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
Score = 63.9 bits (154), Expect = 4e-10
Identities = 45/154 (29%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 311 AATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFET 370
AA +++ T A CL P D C R+++D +C F +G C N N+F T
Sbjct: 19 AALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYT 78
Query: 371 YEACMLAC--MSGPLAACSLP-ALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFE 427
+EAC AC + C L ++ C+ ++ +N + C+ F GGC + N E
Sbjct: 79 WEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGC--HRNRIE 136
Query: 428 SREACEESCPFPRGNQRCRACKPRQKLVTSFCRS 461
+R E +C C P K + SFC S
Sbjct: 137 NRFPDEATC--------MGFCAP--KKIPSFCYS 160
Score = 41.2 bits (95), Expect = 0.003
Identities = 20/65 (30%), Positives = 29/65 (44%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAACS 387
C P D C TR++F+ + C FT+ C N N+F + E C AC
Sbjct: 158 CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKKKKK 217
Query: 388 LPALQ 392
+P L+
Sbjct: 218 MPKLR 222
>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
[Homo sapiens]
Length = 751
Score = 68.2 bits (165), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 384 AACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
A CS A+ GPC+A PRW ++ G+C F+YGGC GN NNFES + C C
Sbjct: 308 AVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 44.3 bits (103), Expect = 3e-04
Identities = 18/53 (33%), Positives = 26/53 (49%)
Query: 326 AECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378
A C + + C RW+FD C+ F +G C N N+FE+ + CM C
Sbjct: 308 AVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1
[Homo sapiens]
Length = 763
Score = 68.2 bits (165), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 384 AACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
A CS A+ GPC+A PRW ++ G+C F+YGGC GN NNFES + C C
Sbjct: 308 AVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 44.3 bits (103), Expect = 3e-04
Identities = 18/53 (33%), Positives = 26/53 (49%)
Query: 326 AECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378
A C + + C RW+FD C+ F +G C N N+FE+ + CM C
Sbjct: 308 AVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 67.8 bits (164), Expect = 3e-11
Identities = 30/55 (54%), Positives = 34/55 (61%), Gaps = 3/55 (5%)
Query: 386 CSLPALQGPCKAYAPRWAYNSQTGQ---CQSFVYGGCEGNGNNFESREACEESCP 437
CSLP +G C AY RW + + TG C FVYGGC GN N F +REACE CP
Sbjct: 2876 CSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRCP 2930
Score = 36.2 bits (82), Expect = 0.084
Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 3/54 (5%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANN---CLTFTFGHCHRNLNHFETYEACMLAC 378
C P D C RW+ A + C F +G C N N F T EAC C
Sbjct: 2876 CSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929
>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 2 [Homo sapiens]
Length = 117
Score = 65.9 bits (159), Expect = 1e-10
Identities = 26/64 (40%), Positives = 35/64 (54%)
Query: 373 ACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREAC 432
+C C+ C +P GPC AY W Y+ + C FVYGGC+GN NNF+S+ C
Sbjct: 48 SCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 107
Query: 433 EESC 436
+C
Sbjct: 108 LNTC 111
Score = 38.5 bits (88), Expect = 0.017
Identities = 15/51 (29%), Positives = 24/51 (47%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378
C P ++ C W +D + N C F +G C N N+F++ C+ C
Sbjct: 61 CEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 111
>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 1 precursor [Homo sapiens]
Length = 133
Score = 65.9 bits (159), Expect = 1e-10
Identities = 26/64 (40%), Positives = 35/64 (54%)
Query: 373 ACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREAC 432
+C C+ C +P GPC AY W Y+ + C FVYGGC+GN NNF+S+ C
Sbjct: 64 SCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 123
Query: 433 EESC 436
+C
Sbjct: 124 LNTC 127
Score = 38.5 bits (88), Expect = 0.017
Identities = 15/51 (29%), Positives = 24/51 (47%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378
C P ++ C W +D + N C F +G C N N+F++ C+ C
Sbjct: 77 CEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
>gi|145309328 papilin [Homo sapiens]
Length = 1251
Score = 64.7 bits (156), Expect = 2e-10
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Query: 349 QANNCLTFTFGHCHRNLNHFE--TYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNS 406
+ + C FG C+ N+ E C+ C LP+ G C +A RW + +
Sbjct: 688 EPSECRGSQFGCCYDNVATAAGPLGEGCVGQPSHAYPVRCLLPSAHGSCADWAARWYFVA 747
Query: 407 QTGQCQSFVYGGCEGNGNNFESREACEESC 436
GQC F YGGC GN NNF S + C SC
Sbjct: 748 SVGQCNRFWYGGCHGNANNFASEQECMSSC 777
Score = 49.3 bits (116), Expect = 1e-05
Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Query: 322 AFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378
A+P CL P C + RW+F A C F +G CH N N+F + + CM +C
Sbjct: 722 AYPV-RCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSC 777
Score = 34.3 bits (77), Expect = 0.32
Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 15/81 (18%)
Query: 214 NNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVR---GNVVVTNIA 270
N P + G+ + C G P P I W++ + V P H G++V++ +A
Sbjct: 1021 NQPRVVDASPGQRIRMTCRAEGFPPPAIEWQRDGQP----VSSPRHQLQPDGSLVISRVA 1076
Query: 271 QLVIYNAQLQDAGIYTCTARN 291
++D G YTC A N
Sbjct: 1077 --------VEDGGFYTCVAFN 1089
Score = 32.7 bits (73), Expect = 0.93
Identities = 30/126 (23%), Positives = 46/126 (36%), Gaps = 24/126 (19%)
Query: 216 PVHQSVTMGETVSFLCDVVGRPRPEITWEKQ----LEDRENVVMRPNHVRGNVVVTNIAQ 271
P +V G+T LC V G I W + D V P+
Sbjct: 1112 PPTVTVPEGDTARLLCVVAGES-VNIRWSRNGLPVQADGHRVHQSPD-----------GT 1159
Query: 272 LVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVVRGHQAAATSESSPNGTAFPAAECLKP 331
L+IYN + +D G YTC+A + + + VV A + P +C+
Sbjct: 1160 LLIYNLRARDEGSYTCSAYQGSQAVSRSTEVKVVSPAPTAQPRD--------PGRDCVDQ 1211
Query: 332 PDSEDC 337
P+ +C
Sbjct: 1212 PELANC 1217
>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 60.8 bits (146), Expect = 3e-09
Identities = 26/64 (40%), Positives = 33/64 (51%)
Query: 373 ACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREAC 432
AC CM C LP G C A RW ++ + +C F Y GCEGN NNF + +AC
Sbjct: 82 ACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
Query: 433 EESC 436
+C
Sbjct: 142 RTAC 145
Score = 48.9 bits (115), Expect = 1e-05
Identities = 20/52 (38%), Positives = 26/52 (50%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACM 379
C+ P +C E RWHFD + C F + C N N+F +AC ACM
Sbjct: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACM 146
Score = 37.4 bits (85), Expect = 0.038
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 15/78 (19%)
Query: 13 WEQVAALLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQSTCRRE----CET 68
W VA LLLL L L L I++ G+CP + + TC E C T
Sbjct: 20 WRNVAFLLLLSLALEWTSAMLT-KKIKHK-PGLCPKE---------RLTCTTELPDSCNT 68
Query: 69 DQECETYEKCCPNVCGTK 86
D +C+ Y+KCC C K
Sbjct: 69 DFDCKEYQKCCFFACQKK 86
Score = 30.8 bits (68), Expect = 3.5
Identities = 25/77 (32%), Positives = 30/77 (38%), Gaps = 9/77 (11%)
Query: 62 CRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGS 121
C C +D +C +KCC + CG V AR VK P D CLQ
Sbjct: 165 CPPSCHSDIDCPQTDKCCESRCG---FVCARAWTVKKGFCPRKPLLCTKIDKPKCLQD-E 220
Query: 122 ECDIWDGQPVCKCKDRC 138
EC + V KC C
Sbjct: 221 ECPL-----VEKCCSHC 232
>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 60.8 bits (146), Expect = 3e-09
Identities = 26/64 (40%), Positives = 33/64 (51%)
Query: 373 ACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREAC 432
AC CM C LP G C A RW ++ + +C F Y GCEGN NNF + +AC
Sbjct: 82 ACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
Query: 433 EESC 436
+C
Sbjct: 142 RTAC 145
Score = 48.9 bits (115), Expect = 1e-05
Identities = 20/52 (38%), Positives = 26/52 (50%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACM 379
C+ P +C E RWHFD + C F + C N N+F +AC ACM
Sbjct: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACM 146
Score = 37.4 bits (85), Expect = 0.038
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 15/78 (19%)
Query: 13 WEQVAALLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQSTCRRE----CET 68
W VA LLLL L L L I++ G+CP + + TC E C T
Sbjct: 20 WRNVAFLLLLSLALEWTSAMLT-KKIKHK-PGLCPKE---------RLTCTTELPDSCNT 68
Query: 69 DQECETYEKCCPNVCGTK 86
D +C+ Y+KCC C K
Sbjct: 69 DFDCKEYQKCCFFACQKK 86
Score = 30.8 bits (68), Expect = 3.5
Identities = 25/77 (32%), Positives = 30/77 (38%), Gaps = 9/77 (11%)
Query: 62 CRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGS 121
C C +D +C +KCC + CG V AR VK P D CLQ
Sbjct: 165 CPPSCHSDIDCPQTDKCCESRCG---FVCARAWTVKKGFCPRKPLLCTKIDKPKCLQD-E 220
Query: 122 ECDIWDGQPVCKCKDRC 138
EC + V KC C
Sbjct: 221 ECPL-----VEKCCSHC 232
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 60.5 bits (145), Expect = 4e-09
Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 8/125 (6%)
Query: 197 TASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMR 256
T +PE EL+ P + + P VT G TV F C G P+PEI W L + + M+
Sbjct: 235 TITPE--ELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIW---LRNNNELSMK 289
Query: 257 PNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVVRGHQAAATSES 316
+ + + + L+I N Q D GIY C A+NVAG ++ G A T
Sbjct: 290 TD---SRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVI 346
Query: 317 SPNGT 321
P T
Sbjct: 347 QPQNT 351
Score = 45.1 bits (105), Expect = 2e-04
Identities = 40/141 (28%), Positives = 55/141 (39%), Gaps = 16/141 (11%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P + P +V +G V C G P P ITW K + V + + G ++
Sbjct: 525 PVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNK-----DGVQVTES---GKFHISPE 576
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVVRGHQAAATSESSPNGTAFPAAECL 329
L I + DAG Y C ARN G LSV + S NG F A +
Sbjct: 577 GFLTINDVGPADAGRYECVARNTIGSASVSMVLSV-------NVPDVSRNGDPFVATSIV 629
Query: 330 KPPDSEDCGEEQTRWH-FDAQ 349
+ + D TR H FD++
Sbjct: 630 EAIATVDRAINSTRTHLFDSR 650
Score = 43.9 bits (102), Expect = 4e-04
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 7/84 (8%)
Query: 208 AAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT 267
A P + P + V +GE+V+ C G P P I+W + DR + + P V +T
Sbjct: 340 ARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR--GDRTPLPVDP-----RVNIT 392
Query: 268 NIAQLVIYNAQLQDAGIYTCTARN 291
L I N D+G Y C+A N
Sbjct: 393 PSGGLYIQNVVQGDSGEYACSATN 416
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/91 (32%), Positives = 38/91 (41%), Gaps = 16/91 (17%)
Query: 208 AAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEK---QLE-DRENVVMRPNHVRGN 263
A P P + V G+TV F C+ G P P I W K QL DR ++V+ +R
Sbjct: 431 ALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLR-- 488
Query: 264 VVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
I L D G Y C A N+ G
Sbjct: 489 ----------ISGVALHDQGQYECQAVNIIG 509
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 58.9 bits (141), Expect = 1e-08
Identities = 43/151 (28%), Positives = 60/151 (39%), Gaps = 11/151 (7%)
Query: 186 PPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEK 245
PP + + P +P AP L P Q V G V C G P P + WEK
Sbjct: 104 PPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEK 163
Query: 246 ------QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRAD 299
++ D + ++P + L I A+L D+G+Y C ARN G +A
Sbjct: 164 DGMALDEVWDSSHFALQPGRAEDGPGAS--LALRILAARLPDSGVYVCHARNAHGHAQAG 221
Query: 300 FPLSVVRGHQAAATSESSPNGTAFPAAECLK 330
L V HQ + + P+ P E LK
Sbjct: 222 ALLQV---HQPPESPPADPDEAPAPVVEPLK 249
Score = 47.4 bits (111), Expect = 4e-05
Identities = 36/105 (34%), Positives = 49/105 (46%), Gaps = 18/105 (17%)
Query: 200 PETPELDM-AAPALLNNPVHQS-----VTMGETVSFLCDVVGRPRPEITWEKQ----LED 249
PE+P D APA + P+ + V G+ F C V+G+P PEI W + L D
Sbjct: 230 PESPPADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPD 289
Query: 250 RENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
R ++ R G V L + Q +D G+Y C ARN AG
Sbjct: 290 RRRLMYRDRD--GGFV------LKVLYCQAKDRGLYVCAARNSAG 326
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 11/99 (11%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEK---QLEDRENVVMRPNHVRGNVVV 266
P L P V G C V+G P P + WEK QL E + + +++
Sbjct: 12 PCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLL 71
Query: 267 TNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
T A DAG+Y C ARN AG A ++V+
Sbjct: 72 T--------AALPTDAGVYVCRARNAAGEAYAAAAVTVL 102
Score = 29.6 bits (65), Expect = 7.9
Identities = 36/159 (22%), Positives = 65/159 (40%), Gaps = 32/159 (20%)
Query: 206 DMAAPALLNNPVH---------QSVTMGETVSFLCDVVGRPRPEITWEK---QLEDRENV 253
D AA + +PVH + T E V C++ P TW K ++E+ E +
Sbjct: 704 DSAALTIQESPVHILSPQDRVSLTFTTSERVVLTCELSRVDFPA-TWYKDGQKVEESELL 762
Query: 254 VMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVA---GVLRADFPLSVVRGHQA 310
V++ + + +L++ A++QD+G + C V+ GV D P+ +V +
Sbjct: 763 VVKMDGRKH--------RLILPEAKVQDSGEFECRTEGVSAFFGVTVQDPPVHIVDPREH 814
Query: 311 AATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQ 349
+ +EC+ D + RW+ D Q
Sbjct: 815 VFVHAIT--------SECVMLACEVDREDAPVRWYKDGQ 845
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 58.9 bits (141), Expect = 1e-08
Identities = 33/97 (34%), Positives = 43/97 (44%)
Query: 208 AAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT 267
A P + P Q V G TV+F C+ G P+P + W+K+ +P V+
Sbjct: 328 APPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVS 387
Query: 268 NIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L I N Q DAG Y C A VAG + A L V
Sbjct: 388 PTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 424
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 9/95 (9%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P L P++Q V E V F C V G P+P + W+K D RG + +
Sbjct: 241 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLP---------RGRYDIKDD 291
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L I D G Y C A N G + A L+V
Sbjct: 292 YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 326
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 15/89 (16%)
Query: 215 NPVHQSVTMGETVSFLCDVV-GRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVTNIA 270
NP V GE C G P P I W+K +++D+E + +RG
Sbjct: 154 NPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERIS----IRGG------- 202
Query: 271 QLVIYNAQLQDAGIYTCTARNVAGVLRAD 299
+L+I N + DAG+YTC N+ G +D
Sbjct: 203 KLMISNTRKSDAGMYTCVGTNMVGERDSD 231
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 7/89 (7%)
Query: 206 DMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVV 265
D P +L P +Q++ + T C G P P I+W K E R +
Sbjct: 430 DRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLK-----EGFTFPGRDPRATIQ 484
Query: 266 VTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
Q I N ++ D G YTC A + +G
Sbjct: 485 EQGTLQ--IKNLRISDTGTYTCVATSSSG 511
Score = 38.9 bits (89), Expect = 0.013
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P ++ +P V+ GE + C GRP P I W K E E P R + ++
Sbjct: 47 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 106
Query: 270 AQLVIYNAQLQ--DAGIYTCTARNVAG 294
L I + + D G Y C ARN G
Sbjct: 107 FFLRIVHGRRSKPDEGSYVCVARNYLG 133
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 58.9 bits (141), Expect = 1e-08
Identities = 33/97 (34%), Positives = 43/97 (44%)
Query: 208 AAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT 267
A P + P Q V G TV+F C+ G P+P + W+K+ +P V+
Sbjct: 312 APPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVS 371
Query: 268 NIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L I N Q DAG Y C A VAG + A L V
Sbjct: 372 PTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 408
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 9/95 (9%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P L P++Q V E V F C V G P+P + W+K D RG + +
Sbjct: 225 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLP---------RGRYDIKDD 275
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L I D G Y C A N G + A L+V
Sbjct: 276 YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 310
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 15/89 (16%)
Query: 215 NPVHQSVTMGETVSFLCDVV-GRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVTNIA 270
NP V GE C G P P I W+K +++D+E + +RG
Sbjct: 138 NPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERIS----IRGG------- 186
Query: 271 QLVIYNAQLQDAGIYTCTARNVAGVLRAD 299
+L+I N + DAG+YTC N+ G +D
Sbjct: 187 KLMISNTRKSDAGMYTCVGTNMVGERDSD 215
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 7/89 (7%)
Query: 206 DMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVV 265
D P +L P +Q++ + T C G P P I+W K E R +
Sbjct: 414 DRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLK-----EGFTFPGRDPRATIQ 468
Query: 266 VTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
Q I N ++ D G YTC A + +G
Sbjct: 469 EQGTLQ--IKNLRISDTGTYTCVATSSSG 495
Score = 38.9 bits (89), Expect = 0.013
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P ++ +P V+ GE + C GRP P I W K E E P R + ++
Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90
Query: 270 AQLVIYNAQLQ--DAGIYTCTARNVAG 294
L I + + D G Y C ARN G
Sbjct: 91 FFLRIVHGRRSKPDEGSYVCVARNYLG 117
>gi|41406055 amyloid beta A4 protein isoform b precursor [Homo
sapiens]
Length = 751
Score = 58.5 bits (140), Expect = 2e-08
Identities = 24/51 (47%), Positives = 30/51 (58%)
Query: 386 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
CS A GPC+A RW ++ G+C F YGGC GN NNF++ E C C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 48.9 bits (115), Expect = 1e-05
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSG-PLAAC 386
C + ++ C +RW+FD C F +G C N N+F+T E CM C S P A
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAA 350
Query: 387 SLP 389
S P
Sbjct: 351 STP 353
>gi|4502167 amyloid beta A4 protein isoform a precursor [Homo
sapiens]
Length = 770
Score = 58.5 bits (140), Expect = 2e-08
Identities = 24/51 (47%), Positives = 30/51 (58%)
Query: 386 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
CS A GPC+A RW ++ G+C F YGGC GN NNF++ E C C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 45.8 bits (107), Expect = 1e-04
Identities = 19/53 (35%), Positives = 27/53 (50%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMS 380
C + ++ C +RW+FD C F +G C N N+F+T E CM C S
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 343
>gi|209915573 amyloid beta A4 protein isoform f precursor [Homo
sapiens]
Length = 714
Score = 58.5 bits (140), Expect = 2e-08
Identities = 24/51 (47%), Positives = 30/51 (58%)
Query: 386 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
CS A GPC+A RW ++ G+C F YGGC GN NNF++ E C C
Sbjct: 235 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 285
Score = 45.8 bits (107), Expect = 1e-04
Identities = 19/53 (35%), Positives = 27/53 (50%)
Query: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMS 380
C + ++ C +RW+FD C F +G C N N+F+T E CM C S
Sbjct: 235 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 287
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 58.2 bits (139), Expect = 2e-08
Identities = 37/97 (38%), Positives = 47/97 (48%), Gaps = 6/97 (6%)
Query: 209 APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVR-GNVVVT 267
AP PV +VT G T C+V G P+P ITW+ REN ++ VR ++
Sbjct: 479 APVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWK-----RENHILASGSVRIPRFMLL 533
Query: 268 NIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L I +QDAG YTC A N G L A L+V
Sbjct: 534 ESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTV 570
Score = 32.7 bits (73), Expect = 0.93
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 6/85 (7%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
S + ETV C +G P P + W K + R + R V+ + L I +
Sbjct: 397 SAEVEETVDIGCQAMGVPLPTLQWYKDAIS----ISRLQNPRYKVLAS--GGLRIQKLRP 450
Query: 280 QDAGIYTCTARNVAGVLRADFPLSV 304
+D+GI+ C A N G ++ L V
Sbjct: 451 EDSGIFQCFASNEGGEIQTHTYLDV 475
>gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
Length = 513
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/44 (54%), Positives = 26/44 (59%)
Query: 393 GPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
G CK PRW YN + C F YGGC GN NNFE + C ESC
Sbjct: 382 GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 425
Score = 52.0 bits (123), Expect = 1e-06
Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 393 GPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRCR------ 446
G C+ PRW Y+ C+SFVYGGC GN NN+ E C +C +G R
Sbjct: 257 GRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPSMERRHPVCS 316
Query: 447 -ACKPRQKLVTSFCRSD 462
C+P Q ++ C D
Sbjct: 317 GTCQPTQFRCSNGCCID 333
Score = 48.9 bits (115), Expect = 1e-05
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 323 FPA--AECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378
FP+ C+ PD+ C E RW+++ + +C FT+G C+ N N+FE + C+ +C
Sbjct: 368 FPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 425
Score = 47.0 bits (110), Expect = 5e-05
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 12/100 (12%)
Query: 309 QAAATSESSPNGTAFPAAECLKPPDSED----------CGEEQTRWHFDAQANNCLTFTF 358
Q TS P TA L +ED C RW++D C +F +
Sbjct: 221 QLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVY 280
Query: 359 GHCHRNLNHFETYEACMLAC--MSGPLAACSLPALQGPCK 396
G C N N++ E C+LAC + GP P G C+
Sbjct: 281 GGCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQ 320
>gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
Length = 513
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/44 (54%), Positives = 26/44 (59%)
Query: 393 GPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
G CK PRW YN + C F YGGC GN NNFE + C ESC
Sbjct: 382 GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 425
Score = 52.0 bits (123), Expect = 1e-06
Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 393 GPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRCR------ 446
G C+ PRW Y+ C+SFVYGGC GN NN+ E C +C +G R
Sbjct: 257 GRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPSMERRHPVCS 316
Query: 447 -ACKPRQKLVTSFCRSD 462
C+P Q ++ C D
Sbjct: 317 GTCQPTQFRCSNGCCID 333
Score = 48.9 bits (115), Expect = 1e-05
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 323 FPA--AECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378
FP+ C+ PD+ C E RW+++ + +C FT+G C+ N N+FE + C+ +C
Sbjct: 368 FPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 425
Score = 47.0 bits (110), Expect = 5e-05
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 12/100 (12%)
Query: 309 QAAATSESSPNGTAFPAAECLKPPDSED----------CGEEQTRWHFDAQANNCLTFTF 358
Q TS P TA L +ED C RW++D C +F +
Sbjct: 221 QLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVY 280
Query: 359 GHCHRNLNHFETYEACMLAC--MSGPLAACSLPALQGPCK 396
G C N N++ E C+LAC + GP P G C+
Sbjct: 281 GGCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQ 320
>gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1
precursor [Homo sapiens]
Length = 529
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/44 (54%), Positives = 26/44 (59%)
Query: 393 GPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
G CK PRW YN + C F YGGC GN NNFE + C ESC
Sbjct: 398 GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441
Score = 50.4 bits (119), Expect = 4e-06
Identities = 21/44 (47%), Positives = 26/44 (59%)
Query: 393 GPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
G C+ PRW Y+ C+SFVYGGC GN NN+ E C +C
Sbjct: 257 GRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
Score = 48.9 bits (115), Expect = 1e-05
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 323 FPA--AECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378
FP+ C+ PD+ C E RW+++ + +C FT+G C+ N N+FE + C+ +C
Sbjct: 384 FPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/92 (30%), Positives = 36/92 (39%), Gaps = 13/92 (14%)
Query: 309 QAAATSESSPNGTAFPAAECLKPPDSED----------CGEEQTRWHFDAQANNCLTFTF 358
Q TS P TA L +ED C RW++D C +F +
Sbjct: 221 QLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVY 280
Query: 359 GHCHRNLNHFETYEACMLAC---MSGPLAACS 387
G C N N++ E C+LAC GPL S
Sbjct: 281 GGCLGNKNNYLREEECILACRGVQGGPLRGSS 312
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 57.4 bits (137), Expect = 4e-08
Identities = 34/100 (34%), Positives = 49/100 (49%), Gaps = 11/100 (11%)
Query: 209 APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT- 267
APA ++ P Q++ G+ V F C++ G P PEI W K P + NV ++
Sbjct: 33133 APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKN--------NLPISISSNVSISR 33184
Query: 268 --NIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
N+ L I NA + D+G YT A+N G A L V+
Sbjct: 33185 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 33224
Score = 50.8 bits (120), Expect = 3e-06
Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 5/115 (4%)
Query: 190 ETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED 249
E + T P E+ + P L++ + +V GE+V+ C + G P P +TW
Sbjct: 923 EAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY----- 977
Query: 250 RENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
RE+ + + + IA+L+I A +D+G +TC+A N AG + L+V
Sbjct: 978 REDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 49.3 bits (116), Expect = 1e-05
Identities = 29/79 (36%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 216 PVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIY 275
PV + +GE+ +F C V G +ITW K +N +RP +V N A L +
Sbjct: 7218 PVSVDLALGESGTFKCHVTGTAPIKITWAK-----DNREIRPGGNYKMTLVENTATLTVL 7272
Query: 276 NAQLQDAGIYTCTARNVAG 294
DAG YTC A N+AG
Sbjct: 7273 KVGKGDAGQYTCYASNIAG 7291
Score = 45.8 bits (107), Expect = 1e-04
Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 183 NTSPPPPETTMHPTTASPETPELDM--AAPALLNNPVHQSVTMGETVSFLCDVVGRPRPE 240
N SPP + A P +D+ A +LL +V G V V G+P P
Sbjct: 19273 NISPPSEPSDPVTILAENVPPRIDLSVAMKSLL------TVKAGTNVCLDATVFGKPMPT 19326
Query: 241 ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADF 300
++W+K + +++P + N+ L +++ +D+G YT TA N +G A
Sbjct: 19327 VSWKK-----DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATI 19381
Query: 301 PLSVV--RGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFD 347
L V+ G A+ + A + E P ED G E T + D
Sbjct: 19382 KLKVLDKPGPPASVKINKMYSDRAMLSWE----PPLEDGGSEITNYIVD 19426
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 11/94 (11%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
E PEL + A N Q + +G+T+ + G P P++TW+K EDR+ P
Sbjct: 17214 EPPELILDA----NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKK--EDRD----APTKA 17263
Query: 261 RGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
R +V ++L I NA +D GIY+ T N AG
Sbjct: 17264 RIDVTPVG-SKLEIRNAAHEDGGIYSLTVENPAG 17296
Score = 44.3 bits (103), Expect = 3e-04
Identities = 36/116 (31%), Positives = 47/116 (40%), Gaps = 13/116 (11%)
Query: 190 ETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQ--- 246
+T++ A P P AAP + PV Q + G +V F C V G P+P + W+K
Sbjct: 1066 DTSLTEEQAGPGEP----AAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1121
Query: 247 LEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPL 302
L + N G +LVI DAG YT RN G A L
Sbjct: 1122 LTTGYRYKVSYNKQTGE------CKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 44.3 bits (103), Expect = 3e-04
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%)
Query: 223 MGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDA 282
+G++VS C V G P ++W K + +RP N+A LV + D+
Sbjct: 6092 VGDSVSLQCQVAGTPEITVSWYKG-----DTKLRPTPEYRTYFTNNVATLVFNKVNINDS 6146
Query: 283 GIYTCTARNVAG 294
G YTC A N G
Sbjct: 6147 GEYTCKAENSIG 6158
Score = 43.1 bits (100), Expect = 7e-04
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 6/112 (5%)
Query: 233 VVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNV 292
+ G+P P ++W+K ED R + V + V T L++Y+ Q DAG YT T +NV
Sbjct: 20006 IKGKPAPSVSWKKG-EDPLATDTRVS-VESSAVNTT---LIVYDCQKSDAGKYTITLKNV 20060
Query: 293 AGVLRADFPLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRW 344
AG + VV G T + A P +D G E T +
Sbjct: 20061 AGTKEGTISIKVV-GKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY 20111
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/92 (35%), Positives = 38/92 (41%), Gaps = 11/92 (11%)
Query: 216 PVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT---NIAQL 272
PV V GE+ F C V G ITW K +N +RP GN +T N L
Sbjct: 6277 PVSIDVIAGESADFECHVTGAQPMRITWSK-----DNKEIRPG---GNYTITCVGNTPHL 6328
Query: 273 VIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
I D+G YTC A N G LSV
Sbjct: 6329 RILKVGKGDSGQYTCQATNDVGKDMCSAQLSV 6360
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
V G V+ + + G P P +TW K + D + V+ HV +VV + LVI +
Sbjct: 16128 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCTLVIPQS 16186
Query: 278 QLQDAGIYTCTARNVAGVLRADFPLSVV 305
+ D G+YT TA N G + L+V+
Sbjct: 16187 RRSDTGLYTITAVNNLGTASKEMRLNVL 16214
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 5/85 (5%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P L+ P + +G+ F+C V G P E W+K D + PN + +I
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQK---DGAALSPSPNWRISDAENKHI 3607
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAG 294
+L N +QD G+Y+C A N G
Sbjct: 3608 LEL--SNLTIQDRGVYSCKASNKFG 3630
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 20/158 (12%)
Query: 156 RC-YMDAEACSKGITLAVVTCRYHF-----TWPNTSPPPPETTMHPTTASPETPELDMAA 209
RC + D C +T RY F T PP +++ T P +
Sbjct: 27902 RCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFG 27961
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P + + +S GE++ V GRP P +TW K + E R N+ +T++
Sbjct: 27962 PEYFDGLIIKS---GESLRIKALVQGRPVPRVTWFKDGVEIEK--------RMNMEITDV 28010
Query: 270 ---AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L + +A G+YT A+N +G +A+ + V
Sbjct: 28011 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 28048
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 7/111 (6%)
Query: 209 APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTN 268
A +L P +V GE+ F CD G P P +TW ++ + + R V T
Sbjct: 32560 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQ------VLSTSARHQVTTTK 32613
Query: 269 I-AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVVRGHQAAATSESSP 318
+ I + Q D G Y+ N G A+F L++ + S P
Sbjct: 32614 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPP 32664
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAG 283
G++ +F C + G P+ ++W L+ E ++ + G + +A I A+++++G
Sbjct: 4876 GQSTTFECQITGTPKIRVSW--YLDGNEITAIQKH---GISFIDGLATFQISGARVENSG 4930
Query: 284 IYTCTARNVAGVLRADFPLSV 304
Y C ARN AG L V
Sbjct: 4931 TYVCEARNDAGTASCSIELKV 4951
Score = 41.2 bits (95), Expect = 0.003
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 5/84 (5%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQ 280
V++G++ S C + G P ++W K + +RP N+A LV +
Sbjct: 7972 VSVGDSASLQCQLAGTPEIGVSWYKG-----DTKLRPTTTYKMHFRNNVATLVFNQVDIN 8026
Query: 281 DAGIYTCTARNVAGVLRADFPLSV 304
D+G Y C A N G + A L+V
Sbjct: 8027 DSGEYICKAENSVGEVSASTFLTV 8050
Score = 41.2 bits (95), Expect = 0.003
Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
Query: 196 TTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVM 255
T S +T AP + + +GE C +VGRP P+I W + +E +
Sbjct: 30519 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR--FGKELIQS 30576
Query: 256 RPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
R + + L + + +D G+YTC A N G
Sbjct: 30577 RKYKMSSD---GRTHTLTVMTEEQEDEGVYTCIATNEVG 30612
Score = 40.4 bits (93), Expect = 0.004
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P +L +V G+ F + GRP+P+I+W K+ E + + + T
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYT-- 3295
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L++ A +DA +YTC A+N GV LSV
Sbjct: 3296 --LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3328
Score = 40.4 bits (93), Expect = 0.004
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 21/113 (18%)
Query: 188 PPETTMHPTTASPETP---ELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWE 244
PP T T A P+ P ELD++ + + G+T+ V GRP P W
Sbjct: 15086 PPGETQPVTVAEPQEPPAVELDVSVKGGIQ------IMAGKTLRIPAVVTGRPVPTKVWT 15139
Query: 245 KQLEDRENVVMRPNHVRGNVVVTNI---AQLVIYNAQLQDAGIYTCTARNVAG 294
K+ + + + VV+ N+ ++L+I +A +D G Y TA N G
Sbjct: 15140 KEEGELD---------KDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCG 15183
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 7/85 (8%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEK-QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
V E + C + G P ++ W K + E +E+ R + V ++A L ++N +
Sbjct: 7317 VKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFV------DSVAVLEMHNLSV 7370
Query: 280 QDAGIYTCTARNVAGVLRADFPLSV 304
+D+G YTC A N AG + L V
Sbjct: 7371 EDSGDYTCEAHNAAGSASSSTSLKV 7395
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/106 (23%), Positives = 44/106 (41%), Gaps = 7/106 (6%)
Query: 200 PETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED-RENVVMRPN 258
P+ PE + P ++ +V+ F G PRP W K + + + +
Sbjct: 32842 PKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 32901
Query: 259 HVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
+G L I+ D+G+YTCT +N AG + + L++
Sbjct: 32902 EDKGGFF------LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 32941
Score = 39.7 bits (91), Expect = 0.008
Identities = 32/126 (25%), Positives = 48/126 (38%), Gaps = 6/126 (4%)
Query: 183 NTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEIT 242
N S PE+ +H E+ AAP + V +G F C++ P
Sbjct: 3430 NLSLEAPESILHERIEQEIEMEMK-AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQ 3488
Query: 243 WEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPL 302
W K RE +R + +++ L I Q+ D G YTC A N G + L
Sbjct: 3489 WFKA--GREIYESDKCSIRSSKYISS---LEILRTQVVDCGEYTCKASNEYGSVSCTATL 3543
Query: 303 SVVRGH 308
+V +
Sbjct: 3544 TVTEAY 3549
Score = 39.7 bits (91), Expect = 0.008
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 5/87 (5%)
Query: 218 HQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
H +GE + C V G P I+W K E+ +R N+A LVI
Sbjct: 7028 HVEAVIGEPATLQCKVDGTPEIRISWYK-----EHTKLRSAPAYKMQFKNNVASLVINKV 7082
Query: 278 QLQDAGIYTCTARNVAGVLRADFPLSV 304
D G Y+C A N G + + L +
Sbjct: 7083 DHSDVGEYSCKADNSVGAVASSAVLVI 7109
Score = 39.3 bits (90), Expect = 0.010
Identities = 34/107 (31%), Positives = 44/107 (41%), Gaps = 11/107 (10%)
Query: 193 MHPTTASPETPELDMAA---PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED 249
M P ET E + P + PV G+T F VVGRP PE W D
Sbjct: 1437 MSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFW---FHD 1493
Query: 250 RENVVMRPNHVRGNVVV--TNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ +V N VV+ L+I A D+G +T A+N AG
Sbjct: 1494 GQQIV---NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG 1537
Score = 39.3 bits (90), Expect = 0.010
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 7/87 (8%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLV-IYNAQ 278
S+ GE + V+GRPRP I+W K E + R NV T + ++ I
Sbjct: 24322 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQT------TRVNVEETATSTVLHIKEGN 24375
Query: 279 LQDAGIYTCTARNVAGVLRADFPLSVV 305
D G YT TA N AG + + V+
Sbjct: 24376 KDDFGKYTVTATNSAGTATENLSVIVL 24402
Score = 38.9 bits (89), Expect = 0.013
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 6/100 (6%)
Query: 197 TASPETPELD--MAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVV 254
T P+ EL M AP + Q+V G F VVG+P PE W K E
Sbjct: 2063 TFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE--- 2119
Query: 255 MRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
R + + N+ +LVI + +D+ A N+AG
Sbjct: 2120 -RSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2158
Score = 38.5 bits (88), Expect = 0.017
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 203 PELDMAAPALLNNPVHQSVTM---GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNH 259
PELD+ ++Q + + G+ + V+GRP+P +TW+K + ++ +
Sbjct: 21063 PELDLRG-------IYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKK----GDQILKQTQR 21111
Query: 260 VRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
V T+ L I D+G Y TARN+ G
Sbjct: 21112 VNFETTATSTI-LNINECVRSDSGPYPLTARNIVG 21145
Score = 38.5 bits (88), Expect = 0.017
Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 22/135 (16%)
Query: 202 TPELDMAAPALLNNP--------VHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENV 253
T L++ PA ++ P VH GE VS G+P P ITW+K +++
Sbjct: 31014 TASLEVEVPAKIHLPKTLEGMGAVH--ALRGEVVSIKIPFSGKPDPVITWQK----GQDL 31067
Query: 254 VMRPNHVRGNVVVTNIAQLVIYN-AQLQDAGIYTCTARNVAGVLRADFPLSVV------R 306
+ H + +V + LV N + +DAG Y A+N G+ + L V R
Sbjct: 31068 IDNNGHYQ-VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPR 31126
Query: 307 GHQAAATSESSPNGT 321
G + + S S N T
Sbjct: 31127 GVKVSDVSRDSVNLT 31141
Score = 38.1 bits (87), Expect = 0.022
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 200 PETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNH 259
P ELD+ ++ +V +G+T+ L V GRP P+ITW K+ V++R
Sbjct: 17905 PPEVELDVTCRDVI------TVRVGQTIRILARVKGRPEPDITWTKE----GKVLVREKR 17954
Query: 260 VRGNVVVTNI--AQLVIYNAQLQDAGIYTCTARNVAG 294
V ++ ++ +L I A D G Y +A+N +G
Sbjct: 17955 VD---LIQDLPRVELQIKEAVRADHGKYIISAKNSSG 17988
Score = 38.1 bits (87), Expect = 0.022
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 13/78 (16%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVT-NIAQLVIYN 276
V GE + D+ GRP P I+W K ++E+R R ++ T N L + +
Sbjct: 25801 VKAGEVLKINADIAGRPLPVISWAKDGIEIEER---------ARTEIISTDNHTLLTVKD 25851
Query: 277 AQLQDAGIYTCTARNVAG 294
+D G Y T +NVAG
Sbjct: 25852 CIRRDTGQYVLTLKNVAG 25869
Score = 37.7 bits (86), Expect = 0.029
Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 12/95 (12%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
E PE+D+ A + V V G + V GRP P++TW K D NVV
Sbjct: 18602 EPPEIDLDAS--MRKLV--IVRAGCPIRLFAIVRGRPAPKVTWRKVGID--NVVR----- 18650
Query: 261 RGNV-VVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+G V +V +A LVI N+ D+G Y+ T N AG
Sbjct: 18651 KGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG 18685
Score = 37.7 bits (86), Expect = 0.029
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 3/79 (3%)
Query: 216 PVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIY 275
P S+ G+ ++ C G P PE+TW + H+ ++ L+I
Sbjct: 33335 PSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIEN---TDDLTTLIIM 33391
Query: 276 NAQLQDAGIYTCTARNVAG 294
+ Q QD G+YT + N G
Sbjct: 33392 DVQKQDGGLYTLSLGNEFG 33410
Score = 37.4 bits (85), Expect = 0.038
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
+VT+GET + C V G P + W K + ++ + I+ L I + +
Sbjct: 5714 TVTVGETCTLECKVAGTPELSVEWYK-----DGKLLTSSQKHKFSFYNKISSLRILSVER 5768
Query: 280 QDAGIYTCTARNVAG 294
QDAG YT +N G
Sbjct: 5769 QDAGTYTFQVQNNVG 5783
Score = 37.4 bits (85), Expect = 0.038
Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 16/114 (14%)
Query: 197 TASPETPELDMAAPALLNNPVHQS---VTMGETVSFLCDVVGRPRPEITW---EKQLEDR 250
+ P T + ++ P + +P + V GET DV G+P P I W +K++E+
Sbjct: 23610 STGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEES 23669
Query: 251 ENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
++ + A L++ +A D G Y A NVAG FP++V
Sbjct: 23670 ARCEIKNTDFK--------ALLIVKDAIRIDGGQYILRASNVAG--SKSFPVNV 23713
Score = 37.4 bits (85), Expect = 0.038
Identities = 33/111 (29%), Positives = 45/111 (40%), Gaps = 19/111 (17%)
Query: 190 ETTMHPTTASPE----TPELDMAAPALLNNPVHQSVTM--GETVSFLCDVVGRPRPEITW 243
E T P T PE PELD L++ + + + + G + GRP PEITW
Sbjct: 24005 EATSVPGTVKPEDKLEAPELD------LDSELRKGIVVRAGGSARIHIPFKGRPTPEITW 24058
Query: 244 EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
++ + + V V N QL I N DAG Y N +G
Sbjct: 24059 SREEGEFTDKVQIEKGV-------NYTQLSIDNCDRNDAGKYILKLENSSG 24102
Score = 37.0 bits (84), Expect = 0.049
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 17/118 (14%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQ---LEDRENVVMRPNHVRGNVVV 266
P+ + + + + + +F V G P ITW K L++ +NV + V
Sbjct: 5048 PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYIS--------FV 5099
Query: 267 TNIAQLVIYNAQLQDAGIYTCTARNVAGV------LRADFPLSVVRGHQAAATSESSP 318
++A L I + +G YTC A+N +GV L P +V ++ +E P
Sbjct: 5100 DSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDP 5157
Score = 37.0 bits (84), Expect = 0.049
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 14/120 (11%)
Query: 189 PETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITW---EK 245
P + P TA E M A + V + ++ L G PRP TW +K
Sbjct: 13377 PSEILGPLTADDAFVEPTMDLSAFKDG---LEVIVPNPITILVPSTGYPRPTATWCFGDK 13433
Query: 246 QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
LE + V M+ ++ A+LVI ++ D GIYT N + + ++V+
Sbjct: 13434 VLETGDRVKMK--------TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVI 13485
Score = 37.0 bits (84), Expect = 0.049
Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 11/77 (14%)
Query: 221 VTMGETVSFLCDVVGRPRPEITW---EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
V G V + + GRP P +W +L + E V + + T +A+L I
Sbjct: 29750 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH--------TKVAKLTIRET 29801
Query: 278 QLQDAGIYTCTARNVAG 294
++D G YT +NV G
Sbjct: 29802 TIRDTGEYTLELKNVTG 29818
Score = 36.6 bits (83), Expect = 0.065
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Query: 209 APALLNNPVHQ---SVTMGETVSF-LCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNV 264
AP ++ +P + ++ G+T+ ++G+P P+ +W K +D +RP+ +
Sbjct: 20375 APTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD-----IRPSDITQIT 20429
Query: 265 VVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ L I A +DAG YT TA N G
Sbjct: 20430 STPTSSMLTIKYATRKDAGEYTITATNPFG 20459
Score = 36.2 bits (82), Expect = 0.084
Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 6/103 (5%)
Query: 202 TPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVR 261
T + + P ++ P V GET F C V G P+P++ W N + R
Sbjct: 1833 TDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL------NGQLIRKSKR 1886
Query: 262 GNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
V I L I + + D G TA N GV+ L +
Sbjct: 1887 FRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929
Score = 36.2 bits (82), Expect = 0.084
Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 205 LDMAAPA-LLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGN 263
L + PA ++ P +VT G + C V G P W K + RE +H+
Sbjct: 6639 LTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFK--DGRELSADSKHHI--- 6693
Query: 264 VVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ +A L I A++ D G+Y+ +N G
Sbjct: 6694 TFINKVASLKIPCAEMSDKGLYSFEVKNSVG 6724
Score = 35.8 bits (81), Expect = 0.11
Identities = 28/79 (35%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN---HVRGNVVVTNIA--QLVIY 275
V GE V DV G P P+I W K E V+ +P + V + A +L I
Sbjct: 15410 VKAGEPVHIPADVTGLPMPKIEWSK----NETVIEKPTDALQITKEEVSRSEAKTELSIP 15465
Query: 276 NAQLQDAGIYTCTARNVAG 294
A +D G YT TA N G
Sbjct: 15466 KAVREDKGTYTVTASNRLG 15484
Score = 35.8 bits (81), Expect = 0.11
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 17/97 (17%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQ---LEDRENVVMRP 257
E PE+++ A + S T+ V+ + GRP PE+ WEK L DR +
Sbjct: 25103 EPPEIELDADLRKVVVLRASATLRLFVT----IKGRPEPEVKWEKAEGILTDRAQI---- 25154
Query: 258 NHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
V ++ LVI N D+G Y T N +G
Sbjct: 25155 ------EVTSSFTMLVIDNVTRFDSGRYNLTLENNSG 25185
Score = 35.8 bits (81), Expect = 0.11
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 17/97 (17%)
Query: 201 ETPELDMAAPALLNNPVHQSVTM--GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN 258
E P+L++A + + ++VT+ G ++ + V GRP P ITW KQ D +
Sbjct: 29442 EIPDLELA------DDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS------ 29489
Query: 259 HVRGNVVVT-NIAQLVIYNAQLQDAGIYTCTARNVAG 294
R + T + + L++ DAG YT A N +G
Sbjct: 29490 --RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSG 29524
Score = 35.0 bits (79), Expect = 0.19
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 219 QSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQ 278
Q + G+ C V G P +ITW DRE ++ + V + A L + +
Sbjct: 4309 QLLKKGDATQLACKVTGTPPIKITWFAN--DRE---IKESSKHRMSFVESTAVLRLTDVG 4363
Query: 279 LQDAGIYTCTARNVAG 294
++D+G Y C A+N AG
Sbjct: 4364 IEDSGEYMCEAQNEAG 4379
Score = 35.0 bits (79), Expect = 0.19
Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P+ + S G T +F + G +TW K ++ + +++R N+
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDE----ITEDDNIR-MTFENNV 4540
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
A L + +++ G Y C A+N AG+ R LSV
Sbjct: 4541 ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV 4575
Score = 35.0 bits (79), Expect = 0.19
Identities = 23/90 (25%), Positives = 37/90 (41%), Gaps = 15/90 (16%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITW-----EKQLEDRENVVMRPNHVRGNV 264
P+ + P V G+ V+F + G P ++ W E DR N+
Sbjct: 5893 PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDT------ 5946
Query: 265 VVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+A+L ++N + +G YTC N AG
Sbjct: 5947 ----VAELELFNIDISQSGEYTCVVSNNAG 5972
Score = 35.0 bits (79), Expect = 0.19
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Query: 222 TMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQD 281
T+G V+ C + G ++ W R+ V++R + V N+A L I L
Sbjct: 6187 TVGLPVTLTCRLNGSAPIQVCWY-----RDGVLLRDDENLQTSFVDNVATLKILQTDLSH 6241
Query: 282 AGIYTCTARNVAG 294
+G Y+C+A N G
Sbjct: 6242 SGQYSCSASNPLG 6254
Score = 35.0 bits (79), Expect = 0.19
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 15/96 (15%)
Query: 204 ELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEK-QLEDRENVVMRPNHVRG 262
+LD+ ++N + G ++ + GRP PE+ W K E R+ ++
Sbjct: 22943 DLDLELRKIIN------IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIID------ 22990
Query: 263 NVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRA 298
V ++ LV+ N D+G YT T N +G A
Sbjct: 22991 --VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSA 23024
Score = 34.7 bits (78), Expect = 0.25
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 5/68 (7%)
Query: 227 VSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYT 286
V L +V G P EITW K +N ++R + ++ L I DAG Y
Sbjct: 4410 VMLLAEVAGTPPFEITWFK-----DNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQ 4464
Query: 287 CTARNVAG 294
C N G
Sbjct: 4465 CRVTNEVG 4472
Score = 34.7 bits (78), Expect = 0.25
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAG 283
GE++ C + G P +++W R + + + + ++A L I A +D+G
Sbjct: 6379 GESIQLECKISGSPEIKVSWF-----RNDSELHESWKYNMSFINSVALLTINEASAEDSG 6433
Query: 284 IYTCTARNVAGVLRADFPLSV 304
Y C A N G L+V
Sbjct: 6434 DYICEAHNGVGDASCSTALTV 6454
Score = 34.7 bits (78), Expect = 0.25
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 5/111 (4%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
S +G+ V V G + W L+DR V+ + R + + NIA L + + +
Sbjct: 6561 STLIGDAVELRAIVEGFQPISVVW---LKDRGEVIRESENTRISFI-DNIATLQLGSPEA 6616
Query: 280 QDAGIYTCTARNVAGVLRADFPLSVVRGHQAAATSESSPNGTAFP-AAECL 329
++G Y C +N AG+ L+V+ + E T P A EC+
Sbjct: 6617 SNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECV 6667
Score = 34.7 bits (78), Expect = 0.25
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 15/90 (16%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLE-----DRENVVMRPNHVRGNV 264
P+ + P V G V+F V G P ++W K DR NV +
Sbjct: 7775 PSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLE-------- 7826
Query: 265 VVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
++A+L +++ +G YTC N AG
Sbjct: 7827 --DSVAELELFDVDTSQSGEYTCIVSNEAG 7854
Score = 34.7 bits (78), Expect = 0.25
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 9/94 (9%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
+ P LD+ +L +V G+T+ V G+P PE+ W K + + + R V
Sbjct: 18199 QKPVLDLKLSGVL------TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATD--LTRSPRV 18250
Query: 261 RGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ + + ++ + A+ D G Y TA N AG
Sbjct: 18251 KIDTRADS-SKFSLTKAKRSDGGKYVVTATNTAG 18283
Score = 34.7 bits (78), Expect = 0.25
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIA-QLVIYNAQLQDA 282
GE DV GRP P + W K ++ E + + + + + LV ++ +D+
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGT------AKLEIKIADFSTNLVNKDSTRRDS 21529
Query: 283 GIYTCTARNVAGVLRADFPLSVV 305
G YT TA N G + F + V+
Sbjct: 21530 GAYTLTATNPGGFAKHIFNVKVL 21552
Score = 34.3 bits (77), Expect = 0.32
Identities = 39/147 (26%), Positives = 58/147 (39%), Gaps = 28/147 (19%)
Query: 197 TASPETPELDMAAPALLNNP------VHQSVTM--GETVSFLCDVVGRPRPEITWEKQLE 248
TAS E +A + P V S M GE+ C + G P ++TW K +
Sbjct: 3717 TASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNK 3776
Query: 249 DRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG-------------- 294
+ + N VR V + A L I + +++D+G Y+C A N G
Sbjct: 3777 E----LSESNTVR-MYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 3831
Query: 295 -VLRADFPLSVVRGHQAAATSESSPNG 320
++ P +VRG A E S G
Sbjct: 3832 SFIKTLEPADIVRGTNALLQCEVSGTG 3858
Score = 34.3 bits (77), Expect = 0.32
Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 7/92 (7%)
Query: 206 DMAAPALLNNPVHQSVTM---GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRG 262
++ AP +P ++ V + GET D+ G+P P++ W K ++ E R ++
Sbjct: 24701 EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAAR-MEIKS 24759
Query: 263 NVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ T LV+ + D G Y NV G
Sbjct: 24760 TIQKTT---LVVKDCIRTDGGQYILKLSNVGG 24788
Score = 33.9 bits (76), Expect = 0.42
Identities = 26/100 (26%), Positives = 34/100 (34%), Gaps = 11/100 (11%)
Query: 198 ASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITW---EKQLEDRENVV 254
AS T A P P G V C++ G P E+ W KQ+ + +
Sbjct: 6446 ASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFK 6505
Query: 255 MRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ H L I N + D G Y C A N G
Sbjct: 6506 ITSKHFD--------TSLHILNLEASDVGEYHCKATNEVG 6537
Score = 33.9 bits (76), Expect = 0.42
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 11/88 (12%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRP---NHVRGNVVV 266
P+ + + +G +V C V G + W +D +V P + NV
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGW---FQDGNEIVSGPKCQSSFSENVCT 6797
Query: 267 TNIAQLVIYNAQLQDAGIYTCTARNVAG 294
N++ L + D GIYTC A NVAG
Sbjct: 6798 LNLSLL-----EPSDTGIYTCVAANVAG 6820
Score = 33.9 bits (76), Expect = 0.42
Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 5/81 (6%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAG 283
G +V C V G P ++W E + + N L + + D+G
Sbjct: 7696 GSSVVMECKVYGSPPISVSWF-----HEGNEISSGRKYQTTLTDNTCALTVNMLEESDSG 7750
Query: 284 IYTCTARNVAGVLRADFPLSV 304
YTC A N+AG PL+V
Sbjct: 7751 DYTCIATNMAGSDECSAPLTV 7771
Score = 33.9 bits (76), Expect = 0.42
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 14/92 (15%)
Query: 219 QSVTMGE--TVSFLCDVVGRPRPEITWEK----QLEDRENVVMRPNHVRGNVVVTNIAQL 272
QS+ + E T +F+ V G P P + W K QL V + H +G+ A+L
Sbjct: 8461 QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFI---HQKGDE-----AKL 8512
Query: 273 VIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
I + D+G+Y C A N G + ++ L V
Sbjct: 8513 EIRDTTKTDSGLYRCVAFNEHGEIESNVNLQV 8544
Score = 33.9 bits (76), Expect = 0.42
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 11/97 (11%)
Query: 201 ETPELDMAAPALLNNPVHQSVTM--GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN 258
E E +MA L+ + +++ + G ++ + GRP PE+TW K + +N
Sbjct: 20766 EIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN------ 20819
Query: 259 HVRGNVVVT-NIAQLVIYNAQLQDAGIYTCTARNVAG 294
R N+ T + L+I D G + T N AG
Sbjct: 20820 --RANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 20854
Score = 33.9 bits (76), Expect = 0.42
Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 13/104 (12%)
Query: 203 PELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRG 262
PELD+ A N V G ++ GRP P W K + +R
Sbjct: 28355 PELDIDA----NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS--------LRA 28402
Query: 263 NVVVTN-IAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
++ T+ + L + N DAG YT T N +G F + V+
Sbjct: 28403 DIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVL 28446
Score = 33.9 bits (76), Expect = 0.42
Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 9/111 (8%)
Query: 198 ASPETPELDMA--APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED--RENV 253
+ P TP+ D+ AP + +V + +C V G P+P + W +Q ++ + +
Sbjct: 30914 SEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGL 30973
Query: 254 VMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
R +G QL+I + DA +Y A N G + L V
Sbjct: 30974 KYRIQEFKG-----GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 31019
Score = 33.5 bits (75), Expect = 0.55
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 7/72 (9%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLED-RENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDA 282
G+TV+ V G +TW K E RE+ ++ + G +A L+I + Q+
Sbjct: 3938 GQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNG------VAVLIIPDVQISFG 3991
Query: 283 GIYTCTARNVAG 294
G YTC A N AG
Sbjct: 3992 GKYTCLAENEAG 4003
Score = 33.5 bits (75), Expect = 0.55
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQ 280
VT G+ + V G P + W K + R V + + N+AQL Y+A+L
Sbjct: 4028 VTAGDPATLEYTVAGTPELKPKWYK--DGRPLVASKKYRISFK---NNVAQLKFYSAELH 4082
Query: 281 DAGIYTCTARNVAG 294
D+G YT N G
Sbjct: 4083 DSGQYTFEISNEVG 4096
Score = 33.5 bits (75), Expect = 0.55
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 19/121 (15%)
Query: 186 PPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEK 245
PPP ++T+ P LL N Q G++V F V G P P + WEK
Sbjct: 31786 PPPTDSTLRPMFKR------------LLANAECQE---GQSVCFEIRVSGIPPPTLKWEK 31830
Query: 246 QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
D + + + PN + + A L I + +D G Y TA N AG L V
Sbjct: 31831 ---DGQPLSLGPNIEIIHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886
Query: 306 R 306
R
Sbjct: 31887 R 31887
Score = 33.1 bits (74), Expect = 0.71
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Query: 217 VHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYN 276
VH+ T+G V+F C + G +++W K + V+++ + V N+A L I
Sbjct: 7125 VHE--TLGFPVAFECRINGSEPLQVSWYK-----DGVLLKDDANLQTSFVHNVATLQILQ 7177
Query: 277 AQLQDAGIYTCTARNVAG 294
G Y C+A N G
Sbjct: 7178 TDQSHIGQYNCSASNPLG 7195
Score = 33.1 bits (74), Expect = 0.71
Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 15/124 (12%)
Query: 185 SPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWE 244
S P T + E PE+ + L +V G + V G+P P+ITW
Sbjct: 13670 SKPSRPTEEIQAVDTQEAPEIFLDVKLLAG----LTVKAGTKIELPATVTGKPEPKITWT 13725
Query: 245 KQLEDRENVVMRPNHVRGNVVVTNI---AQLVIYNAQLQDAGIYTCTARNVAGVLRADFP 301
K +++++ + + + N+ + + I +++ D G Y A NV G A
Sbjct: 13726 K-----ADMILKQDK---RITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVE 13777
Query: 302 LSVV 305
++V+
Sbjct: 13778 VNVL 13781
Score = 33.1 bits (74), Expect = 0.71
Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 202 TPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVR 261
+P+L + A VH G + + V G+P P +TW N+ R
Sbjct: 16521 SPDLQLDASVRDRIVVHA----GGVIRIIAYVSGKPPPTVTW--------NMNERTLPQE 16568
Query: 262 GNVVVTNIAQ-LVIYNAQLQDAGIYTCTARNVAG 294
+ T I+ +VI N Q G+Y+ A+N AG
Sbjct: 16569 ATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 16602
Score = 33.1 bits (74), Expect = 0.71
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
+V GE + +GRP P +TW K +NV ++ N + L I +A
Sbjct: 22158 TVLAGEDLKVDVPFIGRPTPAVTWHK-----DNVPLKQTTRVNAESTENNSLLTIKDACR 22212
Query: 280 QDAGIYTCTARNVAG 294
+D G Y N AG
Sbjct: 22213 EDVGHYVVKLTNSAG 22227
Score = 33.1 bits (74), Expect = 0.71
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 7/75 (9%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIA-QLVIYNAQL 279
V GE+ D+ G+P P I W K ++ N R + T+ A L + +A
Sbjct: 22555 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNT------ARLEIKSTDFATSLSVKDAVR 22608
Query: 280 QDAGIYTCTARNVAG 294
D+G Y A+NVAG
Sbjct: 22609 VDSGNYILKAKNVAG 22623
Score = 33.1 bits (74), Expect = 0.71
Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 9/94 (9%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
E PE+D+ AL + + ++ GE V L GRP P +TW K D +N+ +
Sbjct: 27267 EAPEIDLDV-ALRTSVIAKA---GEDVQVLIPFKGRPPPTVTWRK---DEKNLGSDARYS 27319
Query: 261 RGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
N +++ L I D G Y T N G
Sbjct: 27320 IENTDSSSL--LTIPQVTRNDTGKYILTIENGVG 27351
Score = 32.7 bits (73), Expect = 0.93
Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Query: 223 MGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDA 282
+GE+ F C V G +++W K + RE +R + N A L + D+
Sbjct: 8166 VGESADFECHVTGTQPIKVSWAK--DSRE---IRSGGKYQISYLENSAHLTVLKVDKGDS 8220
Query: 283 GIYTCTARNVAG 294
G YTC A N G
Sbjct: 8221 GQYTCYAVNEVG 8232
Score = 32.7 bits (73), Expect = 0.93
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 11/88 (12%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
V GE +S P P ++W K +++ + + M+ +H+ A L + +
Sbjct: 14398 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHIS--------AHLEVPKS 14449
Query: 278 QLQDAGIYTCTARNVAGVLRADFPLSVV 305
DAGIYT T N G A + V+
Sbjct: 14450 VRADAGIYTITLENKLGSATASINVKVI 14477
Score = 32.7 bits (73), Expect = 0.93
Identities = 21/85 (24%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P + P ++ G+ + V G+P P W+K E+ V+ +H+ + ++
Sbjct: 18899 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKG----EDEVVTSSHLAVHKADSS- 18953
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAG 294
+ L+I + +D+G Y+ TA N +G
Sbjct: 18954 SILIIKDVTRKDSGYYSLTAENSSG 18978
Score = 32.3 bits (72), Expect = 1.2
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQ 280
VT + ++ C V G P ++ W L+D + +V P+ N+A I + Q
Sbjct: 5152 VTEKDPMTLECVVAGTPELKVKW---LKDGKQIV--PSRYFSMSFENNVASFRIQSVMKQ 5206
Query: 281 DAGIYTCTARNVAGVLRADFPLSVV 305
D+G YT N G D L V+
Sbjct: 5207 DSGQYTFKVENDFGSSSCDAYLRVL 5231
Score = 32.3 bits (72), Expect = 1.2
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT-NIAQLVIYNAQ 278
SV +G+ + + GRP+P ITW K + + ++ R NV + ++ L I
Sbjct: 23240 SVQVGQDLKIEVPISGRPKPTITWTK-----DGLPLKQT-TRINVTDSLDLTTLSIKETH 23293
Query: 279 LQDAGIYTCTARNVAG 294
D G Y T NV G
Sbjct: 23294 KDDGGQYGITVANVVG 23309
Score = 32.3 bits (72), Expect = 1.2
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAG 283
G +V + G+P P I W K +D+E ++ N + T++A ++I +A ++G
Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYK--DDKE---LQTNALVCVENTTDLASILIKDADRLNSG 26941
Query: 284 IYTCTARNVAGVLRADFPLSVV 305
Y RN G A + ++
Sbjct: 26942 CYELKLRNAMGSASATIRVQIL 26963
Score = 32.0 bits (71), Expect = 1.6
Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 9/135 (6%)
Query: 171 AVVTCRYHFTWPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTM-GETVSF 229
AV TC + + + P SP+ E+ + PA++ P+ +VT G+ F
Sbjct: 3307 AVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ-EMPVYPPAIIT-PLQDTVTSEGQPARF 3364
Query: 230 LCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTA 289
C V G +++W + D++ ++P+ + QL I A +D G YT A
Sbjct: 3365 QCRVSGTDL-KVSWYSK--DKK---IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA 3418
Query: 290 RNVAGVLRADFPLSV 304
N G + + LS+
Sbjct: 3419 SNAVGQVSSTANLSL 3433
Score = 32.0 bits (71), Expect = 1.6
Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 14/95 (14%)
Query: 205 LDMAAPA-LLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQ----LEDRENVVMRPNH 259
L + PA ++ P VT G+T + C V G P W K D + + N
Sbjct: 7580 LSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNK 7639
Query: 260 VRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
V G L I N D+G+Y+ +N G
Sbjct: 7640 VSG---------LKIINVAPSDSGVYSFEVQNPVG 7665
Score = 31.6 bits (70), Expect = 2.1
Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
+V GE + G + W L+++E V+ ++R V N+A L A+
Sbjct: 5620 TVVAGEPAELQASIEGAQPIFVQW---LKEKEEVIRESENIR-ITFVENVATLQFAKAEP 5675
Query: 280 QDAGIYTCTARNVAGV 295
+AG Y C +N G+
Sbjct: 5676 ANAGKYICQIKNDGGM 5691
Score = 31.6 bits (70), Expect = 2.1
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 6/109 (5%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
+V+ GE V C V G I W K + ++P+ + A L + +
Sbjct: 8356 TVSEGEYVQLSCHVQGSEPIRIQWLKAGRE-----IKPSDRCSFSFASGTAVLELRDVAK 8410
Query: 280 QDAGIYTCTARNVAGVLRADFPLSVV-RGHQAAATSESSPNGTAFPAAE 327
D+G Y C A NVAG +++ + A AT +++ +G F +E
Sbjct: 8411 ADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSE 8459
Score = 31.6 bits (70), Expect = 2.1
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 15/106 (14%)
Query: 202 TPELDMAAPALLNNPVHQ-SVTMGETVSFLCDVVGRPRPEITWEKQ-LEDRENVVMRPNH 259
TPE+D++ + P Q +V +G V G+P+P I+W K L +E+ +R +
Sbjct: 27560 TPEVDLS-----DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSK 27614
Query: 260 VRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
+ L I NA+ + G YT N V R P++V+
Sbjct: 27615 TENKIT------LSIKNAKKEHGGKYTVILDN--AVCRIAVPITVI 27652
Score = 31.6 bits (70), Expect = 2.1
Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 15/98 (15%)
Query: 203 PELDMAAPALLNNPVHQSVTMGETVSFLCDVV--GRPRPEITW---EKQLEDRENVVMRP 257
P+++ A L +Q +T F DV GRP P++TW E +L++ + V +
Sbjct: 28641 PQIEPTAD--LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT 28698
Query: 258 NHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGV 295
R L + ++ D+G Y T N AGV
Sbjct: 28699 TKDR--------TTLTVKDSMRGDSGRYFLTLENTAGV 28728
Score = 31.2 bits (69), Expect = 2.7
Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 7/79 (8%)
Query: 216 PVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIY 275
PV ++ + V C V + +TW K + + P IA L I
Sbjct: 3652 PVQSAIN--KKVHLECQVDEDRKVTVTWSK-----DGQKLPPGKDYKICFEDKIATLEIP 3704
Query: 276 NAQLQDAGIYTCTARNVAG 294
A+L+D+G Y CTA N AG
Sbjct: 3705 LAKLKDSGTYVCTASNEAG 3723
Score = 31.2 bits (69), Expect = 2.7
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 215 NPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVI 274
N + V+ +T+ +C+V +P E+ W K E+ G + LVI
Sbjct: 12468 NLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRI-----LVI 12521
Query: 275 YNAQLQDAGIYTC 287
NA L+DAG Y C
Sbjct: 12522 QNAHLEDAGNYNC 12534
Score = 30.8 bits (68), Expect = 3.5
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 223 MGETVSFLCDVVGRPRPEITW---EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
+G T+ +GRP P +TW +K L++ EN+ + ++V+ N+ +
Sbjct: 30642 VGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKT------ 30695
Query: 280 QDAGIYTCTARNVAGVLRA 298
AG Y NV G + A
Sbjct: 30696 -HAGKYKVQLSNVFGTVDA 30713
Score = 30.4 bits (67), Expect = 4.6
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 208 AAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT 267
A P + S +G+ V + G + W K D+ +V +++ +
Sbjct: 7490 APPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFK---DKGEIVRESDNIWISYS-E 7545
Query: 268 NIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
NIA L + +AG YTC +N AG+ LSV+
Sbjct: 7546 NIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVL 7583
Score = 30.0 bits (66), Expect = 6.0
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAG 283
G V+F C + G P P+I W K + + + + A L I +D G
Sbjct: 1305 GMGVTFHCKMSGYPLPKIAWYKD----GKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1360
Query: 284 IYTCTARNVAG 294
IYT A N+ G
Sbjct: 1361 IYTAFASNIKG 1371
Score = 30.0 bits (66), Expect = 6.0
Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 11/77 (14%)
Query: 221 VTMGETVSFLCDVVGRPRPEITW---EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
V G++ C + G P + W E +L + M + ++A + + N
Sbjct: 5435 VKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRM--------TFIDSVAVIQMNNL 5486
Query: 278 QLQDAGIYTCTARNVAG 294
+D+G + C A+N AG
Sbjct: 5487 STEDSGDFICEAQNPAG 5503
Score = 30.0 bits (66), Expect = 6.0
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 8/95 (8%)
Query: 202 TPELDMAAPALLNNPVHQ-SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
T L + APA ++ S+ G+ + G P +TW+K + + P+
Sbjct: 7859 TTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKN-----GINVTPSQ- 7912
Query: 261 RGNVVVTN-IAQLVIYNAQLQDAGIYTCTARNVAG 294
R N+ T A L I ++ ++DAG Y C N +G
Sbjct: 7913 RCNITTTEKSAILEIPSSTVEDAGQYNCYIENASG 7947
Score = 30.0 bits (66), Expect = 6.0
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 17/129 (13%)
Query: 185 SPPPPETTMHPTTASPETPE--LDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEIT 242
S P T P T E PE +D+ A L G + + GRP P+ +
Sbjct: 15790 SEPSDTTGEIPATDIQEEPEVFIDIGAQDCL------VCKAGSQIRIPAVIKGRPTPKSS 15843
Query: 243 WE------KQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVL 296
WE K ++D + + + N + ++I + G Y+ TA+N AG
Sbjct: 15844 WEFDGKAKKAMKDGVHDIPEDAQLE---TAENSSVIIIPECKRSHTGKYSITAKNKAGQK 15900
Query: 297 RADFPLSVV 305
A+ + V+
Sbjct: 15901 TANCRVKVM 15909
Score = 30.0 bits (66), Expect = 6.0
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 9/73 (12%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI-AQLVIYNAQL 279
V G + + GRP P + W K D R V T+ L I NA
Sbjct: 26198 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRT--------RAYVDTTDSRTSLTIENANR 26249
Query: 280 QDAGIYTCTARNV 292
D+G YT T +NV
Sbjct: 26250 NDSGKYTLTIQNV 26262
Score = 29.6 bits (65), Expect = 7.9
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 11/65 (16%)
Query: 233 VVGRPRPEITW---EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTA 289
V G+P P+I W +K+L+ E V ++ R A VI D+G YT T
Sbjct: 29071 VGGKPEPKIIWTKGDKELDLCEKVSLQYTGKR--------ATAVIKFCDRSDSGKYTLTV 29122
Query: 290 RNVAG 294
+N +G
Sbjct: 29123 KNASG 29127
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 57.4 bits (137), Expect = 4e-08
Identities = 34/100 (34%), Positives = 49/100 (49%), Gaps = 11/100 (11%)
Query: 209 APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT- 267
APA ++ P Q++ G+ V F C++ G P PEI W K P + NV ++
Sbjct: 26828 APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKN--------NLPISISSNVSISR 26879
Query: 268 --NIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
N+ L I NA + D+G YT A+N G A L V+
Sbjct: 26880 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26919
Score = 50.8 bits (120), Expect = 3e-06
Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 5/115 (4%)
Query: 190 ETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED 249
E + T P E+ + P L++ + +V GE+V+ C + G P P +TW
Sbjct: 877 EAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY----- 931
Query: 250 RENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
RE+ + + + IA+L+I A +D+G +TC+A N AG + L+V
Sbjct: 932 REDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 45.8 bits (107), Expect = 1e-04
Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 183 NTSPPPPETTMHPTTASPETPELDM--AAPALLNNPVHQSVTMGETVSFLCDVVGRPRPE 240
N SPP + A P +D+ A +LL +V G V V G+P P
Sbjct: 12968 NISPPSEPSDPVTILAENVPPRIDLSVAMKSLL------TVKAGTNVCLDATVFGKPMPT 13021
Query: 241 ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADF 300
++W+K + +++P + N+ L +++ +D+G YT TA N +G A
Sbjct: 13022 VSWKK-----DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATI 13076
Query: 301 PLSVV--RGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFD 347
L V+ G A+ + A + E P ED G E T + D
Sbjct: 13077 KLKVLDKPGPPASVKINKMYSDRAMLSWE----PPLEDGGSEITNYIVD 13121
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 11/94 (11%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
E PEL + A N Q + +G+T+ + G P P++TW+K EDR+ P
Sbjct: 10909 EPPELILDA----NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKK--EDRD----APTKA 10958
Query: 261 RGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
R +V ++L I NA +D GIY+ T N AG
Sbjct: 10959 RIDVTPVG-SKLEIRNAAHEDGGIYSLTVENPAG 10991
Score = 44.3 bits (103), Expect = 3e-04
Identities = 36/116 (31%), Positives = 47/116 (40%), Gaps = 13/116 (11%)
Query: 190 ETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQ--- 246
+T++ A P P AAP + PV Q + G +V F C V G P+P + W+K
Sbjct: 1020 DTSLTEEQAGPGEP----AAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1075
Query: 247 LEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPL 302
L + N G +LVI DAG YT RN G A L
Sbjct: 1076 LTTGYRYKVSYNKQTGE------CKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 43.1 bits (100), Expect = 7e-04
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 6/112 (5%)
Query: 233 VVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNV 292
+ G+P P ++W+K ED R + V + V T L++Y+ Q DAG YT T +NV
Sbjct: 13701 IKGKPAPSVSWKKG-EDPLATDTRVS-VESSAVNTT---LIVYDCQKSDAGKYTITLKNV 13755
Query: 293 AGVLRADFPLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRW 344
AG + VV G T + A P +D G E T +
Sbjct: 13756 AGTKEGTISIKVV-GKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY 13806
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
V G V+ + + G P P +TW K + D + V+ HV +VV + LVI +
Sbjct: 9823 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCTLVIPQS 9881
Query: 278 QLQDAGIYTCTARNVAGVLRADFPLSVV 305
+ D G+YT TA N G + L+V+
Sbjct: 9882 RRSDTGLYTITAVNNLGTASKEMRLNVL 9909
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 20/158 (12%)
Query: 156 RC-YMDAEACSKGITLAVVTCRYHF-----TWPNTSPPPPETTMHPTTASPETPELDMAA 209
RC + D C +T RY F T PP +++ T P +
Sbjct: 21597 RCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFG 21656
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P + + +S GE++ V GRP P +TW K + E R N+ +T++
Sbjct: 21657 PEYFDGLIIKS---GESLRIKALVQGRPVPRVTWFKDGVEIEK--------RMNMEITDV 21705
Query: 270 ---AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L + +A G+YT A+N +G +A+ + V
Sbjct: 21706 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21743
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 7/111 (6%)
Query: 209 APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTN 268
A +L P +V GE+ F CD G P P +TW ++ + + R V T
Sbjct: 26255 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQ------VLSTSARHQVTTTK 26308
Query: 269 I-AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVVRGHQAAATSESSP 318
+ I + Q D G Y+ N G A+F L++ + S P
Sbjct: 26309 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPP 26359
Score = 41.2 bits (95), Expect = 0.003
Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
Query: 196 TTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVM 255
T S +T AP + + +GE C +VGRP P+I W + +E +
Sbjct: 24214 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR--FGKELIQS 24271
Query: 256 RPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
R + + L + + +D G+YTC A N G
Sbjct: 24272 RKYKMSSD---GRTHTLTVMTEEQEDEGVYTCIATNEVG 24307
Score = 40.4 bits (93), Expect = 0.004
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P +L +V G+ F + GRP+P+I+W K+ E + + + T
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYT-- 3249
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L++ A +DA +YTC A+N GV LSV
Sbjct: 3250 --LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 40.4 bits (93), Expect = 0.004
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 21/113 (18%)
Query: 188 PPETTMHPTTASPETP---ELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWE 244
PP T T A P+ P ELD++ + + G+T+ V GRP P W
Sbjct: 8781 PPGETQPVTVAEPQEPPAVELDVSVKGGIQ------IMAGKTLRIPAVVTGRPVPTKVWT 8834
Query: 245 KQLEDRENVVMRPNHVRGNVVVTNI---AQLVIYNAQLQDAGIYTCTARNVAG 294
K+ + + + VV+ N+ ++L+I +A +D G Y TA N G
Sbjct: 8835 KEEGELD---------KDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8878
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/106 (23%), Positives = 44/106 (41%), Gaps = 7/106 (6%)
Query: 200 PETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED-RENVVMRPN 258
P+ PE + P ++ +V+ F G PRP W K + + + +
Sbjct: 26537 PKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 26596
Query: 259 HVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
+G L I+ D+G+YTCT +N AG + + L++
Sbjct: 26597 EDKGGFF------LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26636
Score = 39.7 bits (91), Expect = 0.008
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 11/99 (11%)
Query: 209 APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQ---LEDRENVVMRPNHVRGNVV 265
AP + + +V G+T FLC + ++TW + +E+ E + N
Sbjct: 3488 APKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNG------ 3541
Query: 266 VTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
NI L I N QL D G+Y+C N G LSV
Sbjct: 3542 --NIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSV 3578
Score = 39.3 bits (90), Expect = 0.010
Identities = 34/107 (31%), Positives = 44/107 (41%), Gaps = 11/107 (10%)
Query: 193 MHPTTASPETPELDMAA---PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED 249
M P ET E + P + PV G+T F VVGRP PE W D
Sbjct: 1391 MSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFW---FHD 1447
Query: 250 RENVVMRPNHVRGNVVV--TNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ +V N VV+ L+I A D+G +T A+N AG
Sbjct: 1448 GQQIV---NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG 1491
Score = 39.3 bits (90), Expect = 0.010
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 190 ETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED 249
E+ ++PT E + P + + ++MG+ + V+G P+P+I W
Sbjct: 3632 ESPVYPTKFDSEK---EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQW-----F 3683
Query: 250 RENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
V++ P+ V + L+I +L+D G YTC A N G
Sbjct: 3684 FNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYG 3728
Score = 39.3 bits (90), Expect = 0.010
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 7/87 (8%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLV-IYNAQ 278
S+ GE + V+GRPRP I+W K E + R NV T + ++ I
Sbjct: 18017 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQT------TRVNVEETATSTVLHIKEGN 18070
Query: 279 LQDAGIYTCTARNVAGVLRADFPLSVV 305
D G YT TA N AG + + V+
Sbjct: 18071 KDDFGKYTVTATNSAGTATENLSVIVL 18097
Score = 38.9 bits (89), Expect = 0.013
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 6/100 (6%)
Query: 197 TASPETPELD--MAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVV 254
T P+ EL M AP + Q+V G F VVG+P PE W K E
Sbjct: 2017 TFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE--- 2073
Query: 255 MRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
R + + N+ +LVI + +D+ A N+AG
Sbjct: 2074 -RSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2112
Score = 38.5 bits (88), Expect = 0.017
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 203 PELDMAAPALLNNPVHQSVTM---GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNH 259
PELD+ ++Q + + G+ + V+GRP+P +TW+K + ++ +
Sbjct: 14758 PELDLRG-------IYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKK----GDQILKQTQR 14806
Query: 260 VRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
V T+ L I D+G Y TARN+ G
Sbjct: 14807 VNFETTATSTI-LNINECVRSDSGPYPLTARNIVG 14840
Score = 38.5 bits (88), Expect = 0.017
Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 22/135 (16%)
Query: 202 TPELDMAAPALLNNP--------VHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENV 253
T L++ PA ++ P VH GE VS G+P P ITW+K +++
Sbjct: 24709 TASLEVEVPAKIHLPKTLEGMGAVH--ALRGEVVSIKIPFSGKPDPVITWQK----GQDL 24762
Query: 254 VMRPNHVRGNVVVTNIAQLVIYN-AQLQDAGIYTCTARNVAGVLRADFPLSVV------R 306
+ H + +V + LV N + +DAG Y A+N G+ + L V R
Sbjct: 24763 IDNNGHYQ-VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPR 24821
Query: 307 GHQAAATSESSPNGT 321
G + + S S N T
Sbjct: 24822 GVKVSDVSRDSVNLT 24836
Score = 38.1 bits (87), Expect = 0.022
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 200 PETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNH 259
P ELD+ ++ +V +G+T+ L V GRP P+ITW K+ V++R
Sbjct: 11600 PPEVELDVTCRDVI------TVRVGQTIRILARVKGRPEPDITWTKE----GKVLVREKR 11649
Query: 260 VRGNVVVTNI--AQLVIYNAQLQDAGIYTCTARNVAG 294
V ++ ++ +L I A D G Y +A+N +G
Sbjct: 11650 VD---LIQDLPRVELQIKEAVRADHGKYIISAKNSSG 11683
Score = 38.1 bits (87), Expect = 0.022
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 13/78 (16%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVT-NIAQLVIYN 276
V GE + D+ GRP P I+W K ++E+R R ++ T N L + +
Sbjct: 19496 VKAGEVLKINADIAGRPLPVISWAKDGIEIEER---------ARTEIISTDNHTLLTVKD 19546
Query: 277 AQLQDAGIYTCTARNVAG 294
+D G Y T +NVAG
Sbjct: 19547 CIRRDTGQYVLTLKNVAG 19564
Score = 37.7 bits (86), Expect = 0.029
Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 12/95 (12%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
E PE+D+ A + V V G + V GRP P++TW K D NVV
Sbjct: 12297 EPPEIDLDAS--MRKLV--IVRAGCPIRLFAIVRGRPAPKVTWRKVGID--NVVR----- 12345
Query: 261 RGNV-VVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+G V +V +A LVI N+ D+G Y+ T N AG
Sbjct: 12346 KGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG 12380
Score = 37.7 bits (86), Expect = 0.029
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 3/79 (3%)
Query: 216 PVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIY 275
P S+ G+ ++ C G P PE+TW + H+ ++ L+I
Sbjct: 27030 PSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIEN---TDDLTTLIIM 27086
Query: 276 NAQLQDAGIYTCTARNVAG 294
+ Q QD G+YT + N G
Sbjct: 27087 DVQKQDGGLYTLSLGNEFG 27105
Score = 37.4 bits (85), Expect = 0.038
Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 16/114 (14%)
Query: 197 TASPETPELDMAAPALLNNPVHQS---VTMGETVSFLCDVVGRPRPEITW---EKQLEDR 250
+ P T + ++ P + +P + V GET DV G+P P I W +K++E+
Sbjct: 17305 STGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEES 17364
Query: 251 ENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
++ + A L++ +A D G Y A NVAG FP++V
Sbjct: 17365 ARCEIKNTDFK--------ALLIVKDAIRIDGGQYILRASNVAG--SKSFPVNV 17408
Score = 37.4 bits (85), Expect = 0.038
Identities = 33/111 (29%), Positives = 45/111 (40%), Gaps = 19/111 (17%)
Query: 190 ETTMHPTTASPE----TPELDMAAPALLNNPVHQSVTM--GETVSFLCDVVGRPRPEITW 243
E T P T PE PELD L++ + + + + G + GRP PEITW
Sbjct: 17700 EATSVPGTVKPEDKLEAPELD------LDSELRKGIVVRAGGSARIHIPFKGRPTPEITW 17753
Query: 244 EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
++ + + V V N QL I N DAG Y N +G
Sbjct: 17754 SREEGEFTDKVQIEKGV-------NYTQLSIDNCDRNDAGKYILKLENSSG 17797
Score = 37.0 bits (84), Expect = 0.049
Identities = 28/109 (25%), Positives = 42/109 (38%), Gaps = 5/109 (4%)
Query: 196 TTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVM 255
T S + + AAP + V +G F C++ P W K RE
Sbjct: 4515 TATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKA--GREIYES 4572
Query: 256 RPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
+R + +++ L I Q+ D G YTC A N G + L+V
Sbjct: 4573 DKCSIRSSKYISS---LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618
Score = 37.0 bits (84), Expect = 0.049
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 14/120 (11%)
Query: 189 PETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITW---EK 245
P + P TA E M A + V + ++ L G PRP TW +K
Sbjct: 7072 PSEILGPLTADDAFVEPTMDLSAFKDG---LEVIVPNPITILVPSTGYPRPTATWCFGDK 7128
Query: 246 QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
LE + V M+ ++ A+LVI ++ D GIYT N + + ++V+
Sbjct: 7129 VLETGDRVKMK--------TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVI 7180
Score = 37.0 bits (84), Expect = 0.049
Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 11/77 (14%)
Query: 221 VTMGETVSFLCDVVGRPRPEITW---EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
V G V + + GRP P +W +L + E V + + T +A+L I
Sbjct: 23445 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH--------TKVAKLTIRET 23496
Query: 278 QLQDAGIYTCTARNVAG 294
++D G YT +NV G
Sbjct: 23497 TIRDTGEYTLELKNVTG 23513
Score = 36.6 bits (83), Expect = 0.065
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Query: 209 APALLNNPVHQ---SVTMGETVSF-LCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNV 264
AP ++ +P + ++ G+T+ ++G+P P+ +W K +D +RP+ +
Sbjct: 14070 APTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD-----IRPSDITQIT 14124
Query: 265 VVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ L I A +DAG YT TA N G
Sbjct: 14125 STPTSSMLTIKYATRKDAGEYTITATNPFG 14154
Score = 36.2 bits (82), Expect = 0.084
Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 6/103 (5%)
Query: 202 TPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVR 261
T + + P ++ P V GET F C V G P+P++ W N + R
Sbjct: 1787 TDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL------NGQLIRKSKR 1840
Query: 262 GNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
V I L I + + D G TA N GV+ L +
Sbjct: 1841 FRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 35.8 bits (81), Expect = 0.11
Identities = 28/79 (35%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN---HVRGNVVVTNIA--QLVIY 275
V GE V DV G P P+I W K E V+ +P + V + A +L I
Sbjct: 9105 VKAGEPVHIPADVTGLPMPKIEWSK----NETVIEKPTDALQITKEEVSRSEAKTELSIP 9160
Query: 276 NAQLQDAGIYTCTARNVAG 294
A +D G YT TA N G
Sbjct: 9161 KAVREDKGTYTVTASNRLG 9179
Score = 35.8 bits (81), Expect = 0.11
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 17/97 (17%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQ---LEDRENVVMRP 257
E PE+++ A + S T+ V+ + GRP PE+ WEK L DR +
Sbjct: 18798 EPPEIELDADLRKVVVLRASATLRLFVT----IKGRPEPEVKWEKAEGILTDRAQI---- 18849
Query: 258 NHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
V ++ LVI N D+G Y T N +G
Sbjct: 18850 ------EVTSSFTMLVIDNVTRFDSGRYNLTLENNSG 18880
Score = 35.8 bits (81), Expect = 0.11
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 17/97 (17%)
Query: 201 ETPELDMAAPALLNNPVHQSVTM--GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN 258
E P+L++A + + ++VT+ G ++ + V GRP P ITW KQ D +
Sbjct: 23137 EIPDLELA------DDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS------ 23184
Query: 259 HVRGNVVVT-NIAQLVIYNAQLQDAGIYTCTARNVAG 294
R + T + + L++ DAG YT A N +G
Sbjct: 23185 --RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSG 23219
Score = 35.0 bits (79), Expect = 0.19
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 15/96 (15%)
Query: 204 ELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEK-QLEDRENVVMRPNHVRG 262
+LD+ ++N + G ++ + GRP PE+ W K E R+ ++
Sbjct: 16638 DLDLELRKIIN------IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIID------ 16685
Query: 263 NVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRA 298
V ++ LV+ N D+G YT T N +G A
Sbjct: 16686 --VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSA 16719
Score = 34.7 bits (78), Expect = 0.25
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 9/94 (9%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
+ P LD+ +L +V G+T+ V G+P PE+ W K + + + R V
Sbjct: 11894 QKPVLDLKLSGVL------TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATD--LTRSPRV 11945
Query: 261 RGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ + + ++ + A+ D G Y TA N AG
Sbjct: 11946 KIDTRADS-SKFSLTKAKRSDGGKYVVTATNTAG 11978
Score = 34.7 bits (78), Expect = 0.25
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIA-QLVIYNAQLQDA 282
GE DV GRP P + W K ++ E + + + + + LV ++ +D+
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGT------AKLEIKIADFSTNLVNKDSTRRDS 15224
Query: 283 GIYTCTARNVAGVLRADFPLSVV 305
G YT TA N G + F + V+
Sbjct: 15225 GAYTLTATNPGGFAKHIFNVKVL 15247
Score = 34.3 bits (77), Expect = 0.32
Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 7/92 (7%)
Query: 206 DMAAPALLNNPVHQSVTM---GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRG 262
++ AP +P ++ V + GET D+ G+P P++ W K ++ E R ++
Sbjct: 18396 EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAAR-MEIKS 18454
Query: 263 NVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ T LV+ + D G Y NV G
Sbjct: 18455 TIQKTT---LVVKDCIRTDGGQYILKLSNVGG 18483
Score = 33.9 bits (76), Expect = 0.42
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 11/97 (11%)
Query: 201 ETPELDMAAPALLNNPVHQSVTM--GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN 258
E E +MA L+ + +++ + G ++ + GRP PE+TW K + +N
Sbjct: 14461 EIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN------ 14514
Query: 259 HVRGNVVVT-NIAQLVIYNAQLQDAGIYTCTARNVAG 294
R N+ T + L+I D G + T N AG
Sbjct: 14515 --RANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 14549
Score = 33.9 bits (76), Expect = 0.42
Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 13/104 (12%)
Query: 203 PELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRG 262
PELD+ A N V G ++ GRP P W K + +R
Sbjct: 22050 PELDIDA----NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS--------LRA 22097
Query: 263 NVVVTN-IAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
++ T+ + L + N DAG YT T N +G F + V+
Sbjct: 22098 DIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVL 22141
Score = 33.9 bits (76), Expect = 0.42
Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 9/111 (8%)
Query: 198 ASPETPELDMA--APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED--RENV 253
+ P TP+ D+ AP + +V + +C V G P+P + W +Q ++ + +
Sbjct: 24609 SEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGL 24668
Query: 254 VMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
R +G QL+I + DA +Y A N G + L V
Sbjct: 24669 KYRIQEFKG-----GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24714
Score = 33.5 bits (75), Expect = 0.55
Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 14/67 (20%)
Query: 233 VVGRPRPEITWEKQLEDR-----ENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTC 287
VVG P P +TW K+ + ++ PN ++ + Q +D+G+Y C
Sbjct: 3790 VVGEPAPTVTWFKENKQLCTSVYYTIIHNPN---------GSGTFIVNDPQREDSGLYIC 3840
Query: 288 TARNVAG 294
A N+ G
Sbjct: 3841 KAENMLG 3847
Score = 33.5 bits (75), Expect = 0.55
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 19/121 (15%)
Query: 186 PPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEK 245
PPP ++T+ P LL N Q G++V F V G P P + WEK
Sbjct: 25481 PPPTDSTLRPMFKR------------LLANAECQE---GQSVCFEIRVSGIPPPTLKWEK 25525
Query: 246 QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
D + + + PN + + A L I + +D G Y TA N AG L V
Sbjct: 25526 ---DGQPLSLGPNIEIIHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581
Query: 306 R 306
R
Sbjct: 25582 R 25582
Score = 33.1 bits (74), Expect = 0.71
Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 15/124 (12%)
Query: 185 SPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWE 244
S P T + E PE+ + L +V G + V G+P P+ITW
Sbjct: 7365 SKPSRPTEEIQAVDTQEAPEIFLDVKLLAG----LTVKAGTKIELPATVTGKPEPKITWT 7420
Query: 245 KQLEDRENVVMRPNHVRGNVVVTNI---AQLVIYNAQLQDAGIYTCTARNVAGVLRADFP 301
K +++++ + + + N+ + + I +++ D G Y A NV G A
Sbjct: 7421 K-----ADMILKQDK---RITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVE 7472
Query: 302 LSVV 305
++V+
Sbjct: 7473 VNVL 7476
Score = 33.1 bits (74), Expect = 0.71
Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 202 TPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVR 261
+P+L + A VH G + + V G+P P +TW N+ R
Sbjct: 10216 SPDLQLDASVRDRIVVHA----GGVIRIIAYVSGKPPPTVTW--------NMNERTLPQE 10263
Query: 262 GNVVVTNIAQ-LVIYNAQLQDAGIYTCTARNVAG 294
+ T I+ +VI N Q G+Y+ A+N AG
Sbjct: 10264 ATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 10297
Score = 33.1 bits (74), Expect = 0.71
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
+V GE + +GRP P +TW K +NV ++ N + L I +A
Sbjct: 15853 TVLAGEDLKVDVPFIGRPTPAVTWHK-----DNVPLKQTTRVNAESTENNSLLTIKDACR 15907
Query: 280 QDAGIYTCTARNVAG 294
+D G Y N AG
Sbjct: 15908 EDVGHYVVKLTNSAG 15922
Score = 33.1 bits (74), Expect = 0.71
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 7/75 (9%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIA-QLVIYNAQL 279
V GE+ D+ G+P P I W K ++ N R + T+ A L + +A
Sbjct: 16250 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNT------ARLEIKSTDFATSLSVKDAVR 16303
Query: 280 QDAGIYTCTARNVAG 294
D+G Y A+NVAG
Sbjct: 16304 VDSGNYILKAKNVAG 16318
Score = 33.1 bits (74), Expect = 0.71
Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 9/94 (9%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
E PE+D+ AL + + ++ GE V L GRP P +TW K D +N+ +
Sbjct: 20962 EAPEIDLDV-ALRTSVIAKA---GEDVQVLIPFKGRPPPTVTWRK---DEKNLGSDARYS 21014
Query: 261 RGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
N +++ L I D G Y T N G
Sbjct: 21015 IENTDSSSL--LTIPQVTRNDTGKYILTIENGVG 21046
Score = 32.7 bits (73), Expect = 0.93
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 11/88 (12%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
V GE +S P P ++W K +++ + + M+ +H+ A L + +
Sbjct: 8093 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHIS--------AHLEVPKS 8144
Query: 278 QLQDAGIYTCTARNVAGVLRADFPLSVV 305
DAGIYT T N G A + V+
Sbjct: 8145 VRADAGIYTITLENKLGSATASINVKVI 8172
Score = 32.7 bits (73), Expect = 0.93
Identities = 21/85 (24%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P + P ++ G+ + V G+P P W+K E+ V+ +H+ + ++
Sbjct: 12594 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKG----EDEVVTSSHLAVHKADSS- 12648
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAG 294
+ L+I + +D+G Y+ TA N +G
Sbjct: 12649 SILIIKDVTRKDSGYYSLTAENSSG 12673
Score = 32.3 bits (72), Expect = 1.2
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT-NIAQLVIYNAQ 278
SV +G+ + + GRP+P ITW K + + ++ R NV + ++ L I
Sbjct: 16935 SVQVGQDLKIEVPISGRPKPTITWTK-----DGLPLKQT-TRINVTDSLDLTTLSIKETH 16988
Query: 279 LQDAGIYTCTARNVAG 294
D G Y T NV G
Sbjct: 16989 KDDGGQYGITVANVVG 17004
Score = 32.3 bits (72), Expect = 1.2
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAG 283
G +V + G+P P I W K +D+E ++ N + T++A ++I +A ++G
Sbjct: 20582 GTSVKLRAGISGKPAPTIEWYK--DDKE---LQTNALVCVENTTDLASILIKDADRLNSG 20636
Query: 284 IYTCTARNVAGVLRADFPLSVV 305
Y RN G A + ++
Sbjct: 20637 CYELKLRNAMGSASATIRVQIL 20658
Score = 32.0 bits (71), Expect = 1.6
Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 9/135 (6%)
Query: 171 AVVTCRYHFTWPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTM-GETVSF 229
AV TC + + + P SP+ E+ + PA++ P+ +VT G+ F
Sbjct: 3261 AVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ-EMPVYPPAIIT-PLQDTVTSEGQPARF 3318
Query: 230 LCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTA 289
C V G +++W + D++ ++P+ + QL I A +D G YT A
Sbjct: 3319 QCRVSGTDL-KVSWYSK--DKK---IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA 3372
Query: 290 RNVAGVLRADFPLSV 304
N G + + LS+
Sbjct: 3373 SNAVGQVSSTANLSL 3387
Score = 31.6 bits (70), Expect = 2.1
Identities = 58/237 (24%), Positives = 92/237 (38%), Gaps = 37/237 (15%)
Query: 117 LQQGS------ECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRC----YMDAEACSK 166
+QQG+ E D + G + E E + +++ ++Y+N Y+DA +K
Sbjct: 4324 IQQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTK 4383
Query: 167 GITLAVVTCRYHFTWPNTSPPPPETTMHPTTASPETPELDMAAPALLNNP---VHQSVTM 223
G+ AVV+ S E++ T T ++ A L+ +H +
Sbjct: 4384 GVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLV- 4442
Query: 224 GETVSFLCDVVGRPRPEITWEKQLE-DRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQD- 281
+TVS D+V IT K++ EN ++ + + N LVI +D
Sbjct: 4443 -DTVSEEGDIV-HLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4500
Query: 282 AGIYTCTARNVAG-----------------VLRADFPLSVVRGHQAAATSE--SSPN 319
G Y C A N +G + R PL V GH A T E S+PN
Sbjct: 4501 QGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPN 4557
Score = 31.6 bits (70), Expect = 2.1
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 15/106 (14%)
Query: 202 TPELDMAAPALLNNPVHQ-SVTMGETVSFLCDVVGRPRPEITWEKQ-LEDRENVVMRPNH 259
TPE+D++ + P Q +V +G V G+P+P I+W K L +E+ +R +
Sbjct: 21255 TPEVDLS-----DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSK 21309
Query: 260 VRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
+ L I NA+ + G YT N V R P++V+
Sbjct: 21310 TENKIT------LSIKNAKKEHGGKYTVILDN--AVCRIAVPITVI 21347
Score = 31.6 bits (70), Expect = 2.1
Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 15/98 (15%)
Query: 203 PELDMAAPALLNNPVHQSVTMGETVSFLCDVV--GRPRPEITW---EKQLEDRENVVMRP 257
P+++ A L +Q +T F DV GRP P++TW E +L++ + V +
Sbjct: 22336 PQIEPTAD--LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT 22393
Query: 258 NHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGV 295
R L + ++ D+G Y T N AGV
Sbjct: 22394 TKDR--------TTLTVKDSMRGDSGRYFLTLENTAGV 22423
Score = 31.2 bits (69), Expect = 2.7
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 215 NPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVI 274
N + V+ +T+ +C+V +P E+ W K E+ G + LVI
Sbjct: 6163 NLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRI-----LVI 6216
Query: 275 YNAQLQDAGIYTC 287
NA L+DAG Y C
Sbjct: 6217 QNAHLEDAGNYNC 6229
Score = 30.8 bits (68), Expect = 3.5
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 223 MGETVSFLCDVVGRPRPEITW---EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
+G T+ +GRP P +TW +K L++ EN+ + ++V+ N+ +
Sbjct: 24337 VGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKT------ 24390
Query: 280 QDAGIYTCTARNVAGVLRA 298
AG Y NV G + A
Sbjct: 24391 -HAGKYKVQLSNVFGTVDA 24408
Score = 30.0 bits (66), Expect = 6.0
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAG 283
G V+F C + G P P+I W K + + + + A L I +D G
Sbjct: 1259 GMGVTFHCKMSGYPLPKIAWYKD----GKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1314
Query: 284 IYTCTARNVAG 294
IYT A N+ G
Sbjct: 1315 IYTAFASNIKG 1325
Score = 30.0 bits (66), Expect = 6.0
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 17/129 (13%)
Query: 185 SPPPPETTMHPTTASPETPE--LDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEIT 242
S P T P T E PE +D+ A L G + + GRP P+ +
Sbjct: 9485 SEPSDTTGEIPATDIQEEPEVFIDIGAQDCL------VCKAGSQIRIPAVIKGRPTPKSS 9538
Query: 243 WE------KQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVL 296
WE K ++D + + + N + ++I + G Y+ TA+N AG
Sbjct: 9539 WEFDGKAKKAMKDGVHDIPEDAQLE---TAENSSVIIIPECKRSHTGKYSITAKNKAGQK 9595
Query: 297 RADFPLSVV 305
A+ + V+
Sbjct: 9596 TANCRVKVM 9604
Score = 30.0 bits (66), Expect = 6.0
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 9/73 (12%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI-AQLVIYNAQL 279
V G + + GRP P + W K D R V T+ L I NA
Sbjct: 19893 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRT--------RAYVDTTDSRTSLTIENANR 19944
Query: 280 QDAGIYTCTARNV 292
D+G YT T +NV
Sbjct: 19945 NDSGKYTLTIQNV 19957
Score = 29.6 bits (65), Expect = 7.9
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 11/65 (16%)
Query: 233 VVGRPRPEITW---EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTA 289
V G+P P+I W +K+L+ E V ++ R A VI D+G YT T
Sbjct: 22766 VGGKPEPKIIWTKGDKELDLCEKVSLQYTGKR--------ATAVIKFCDRSDSGKYTLTV 22817
Query: 290 RNVAG 294
+N +G
Sbjct: 22818 KNASG 22822
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 57.4 bits (137), Expect = 4e-08
Identities = 34/100 (34%), Positives = 49/100 (49%), Gaps = 11/100 (11%)
Query: 209 APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT- 267
APA ++ P Q++ G+ V F C++ G P PEI W K P + NV ++
Sbjct: 26761 APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKN--------NLPISISSNVSISR 26812
Query: 268 --NIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
N+ L I NA + D+G YT A+N G A L V+
Sbjct: 26813 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26852
Score = 50.8 bits (120), Expect = 3e-06
Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 5/115 (4%)
Query: 190 ETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED 249
E + T P E+ + P L++ + +V GE+V+ C + G P P +TW
Sbjct: 877 EAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY----- 931
Query: 250 RENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
RE+ + + + IA+L+I A +D+G +TC+A N AG + L+V
Sbjct: 932 REDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 45.8 bits (107), Expect = 1e-04
Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 183 NTSPPPPETTMHPTTASPETPELDM--AAPALLNNPVHQSVTMGETVSFLCDVVGRPRPE 240
N SPP + A P +D+ A +LL +V G V V G+P P
Sbjct: 12901 NISPPSEPSDPVTILAENVPPRIDLSVAMKSLL------TVKAGTNVCLDATVFGKPMPT 12954
Query: 241 ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADF 300
++W+K + +++P + N+ L +++ +D+G YT TA N +G A
Sbjct: 12955 VSWKK-----DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATI 13009
Query: 301 PLSVV--RGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFD 347
L V+ G A+ + A + E P ED G E T + D
Sbjct: 13010 KLKVLDKPGPPASVKINKMYSDRAMLSWE----PPLEDGGSEITNYIVD 13054
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 11/94 (11%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
E PEL + A N Q + +G+T+ + G P P++TW+K EDR+ P
Sbjct: 10842 EPPELILDA----NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKK--EDRD----APTKA 10891
Query: 261 RGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
R +V ++L I NA +D GIY+ T N AG
Sbjct: 10892 RIDVTPVG-SKLEIRNAAHEDGGIYSLTVENPAG 10924
Score = 44.3 bits (103), Expect = 3e-04
Identities = 36/116 (31%), Positives = 47/116 (40%), Gaps = 13/116 (11%)
Query: 190 ETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQ--- 246
+T++ A P P AAP + PV Q + G +V F C V G P+P + W+K
Sbjct: 1020 DTSLTEEQAGPGEP----AAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1075
Query: 247 LEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPL 302
L + N G +LVI DAG YT RN G A L
Sbjct: 1076 LTTGYRYKVSYNKQTGE------CKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 43.1 bits (100), Expect = 7e-04
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 6/112 (5%)
Query: 233 VVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNV 292
+ G+P P ++W+K ED R + V + V T L++Y+ Q DAG YT T +NV
Sbjct: 13634 IKGKPAPSVSWKKG-EDPLATDTRVS-VESSAVNTT---LIVYDCQKSDAGKYTITLKNV 13688
Query: 293 AGVLRADFPLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRW 344
AG + VV G T + A P +D G E T +
Sbjct: 13689 AGTKEGTISIKVV-GKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY 13739
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
V G V+ + + G P P +TW K + D + V+ HV +VV + LVI +
Sbjct: 9756 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCTLVIPQS 9814
Query: 278 QLQDAGIYTCTARNVAGVLRADFPLSVV 305
+ D G+YT TA N G + L+V+
Sbjct: 9815 RRSDTGLYTITAVNNLGTASKEMRLNVL 9842
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 20/158 (12%)
Query: 156 RC-YMDAEACSKGITLAVVTCRYHF-----TWPNTSPPPPETTMHPTTASPETPELDMAA 209
RC + D C +T RY F T PP +++ T P +
Sbjct: 21530 RCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFG 21589
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P + + +S GE++ V GRP P +TW K + E R N+ +T++
Sbjct: 21590 PEYFDGLIIKS---GESLRIKALVQGRPVPRVTWFKDGVEIEK--------RMNMEITDV 21638
Query: 270 ---AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L + +A G+YT A+N +G +A+ + V
Sbjct: 21639 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21676
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 7/111 (6%)
Query: 209 APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTN 268
A +L P +V GE+ F CD G P P +TW ++ + + R V T
Sbjct: 26188 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQ------VLSTSARHQVTTTK 26241
Query: 269 I-AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVVRGHQAAATSESSP 318
+ I + Q D G Y+ N G A+F L++ + S P
Sbjct: 26242 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPP 26292
Score = 41.2 bits (95), Expect = 0.003
Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
Query: 196 TTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVM 255
T S +T AP + + +GE C +VGRP P+I W + +E +
Sbjct: 24147 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR--FGKELIQS 24204
Query: 256 RPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
R + + L + + +D G+YTC A N G
Sbjct: 24205 RKYKMSSD---GRTHTLTVMTEEQEDEGVYTCIATNEVG 24240
Score = 40.4 bits (93), Expect = 0.004
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P +L +V G+ F + GRP+P+I+W K+ E + + + T
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYT-- 3249
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
L++ A +DA +YTC A+N GV LSV
Sbjct: 3250 --LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 40.4 bits (93), Expect = 0.004
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 21/113 (18%)
Query: 188 PPETTMHPTTASPETP---ELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWE 244
PP T T A P+ P ELD++ + + G+T+ V GRP P W
Sbjct: 8714 PPGETQPVTVAEPQEPPAVELDVSVKGGIQ------IMAGKTLRIPAVVTGRPVPTKVWT 8767
Query: 245 KQLEDRENVVMRPNHVRGNVVVTNI---AQLVIYNAQLQDAGIYTCTARNVAG 294
K+ + + + VV+ N+ ++L+I +A +D G Y TA N G
Sbjct: 8768 KEEGELD---------KDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8811
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 3/71 (4%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAG 283
GETV F V G P+PEI W +++ ++ + V T +A ++I +A + AG
Sbjct: 3433 GETVRFHARVSGIPKPEIQW---FHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAG 3489
Query: 284 IYTCTARNVAG 294
Y+C A N AG
Sbjct: 3490 QYSCKAANSAG 3500
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/106 (23%), Positives = 44/106 (41%), Gaps = 7/106 (6%)
Query: 200 PETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED-RENVVMRPN 258
P+ PE + P ++ +V+ F G PRP W K + + + +
Sbjct: 26470 PKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 26529
Query: 259 HVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
+G L I+ D+G+YTCT +N AG + + L++
Sbjct: 26530 EDKGGFF------LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26569
Score = 39.3 bits (90), Expect = 0.010
Identities = 34/107 (31%), Positives = 44/107 (41%), Gaps = 11/107 (10%)
Query: 193 MHPTTASPETPELDMAA---PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED 249
M P ET E + P + PV G+T F VVGRP PE W D
Sbjct: 1391 MSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFW---FHD 1447
Query: 250 RENVVMRPNHVRGNVVV--TNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ +V N VV+ L+I A D+G +T A+N AG
Sbjct: 1448 GQQIV---NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG 1491
Score = 39.3 bits (90), Expect = 0.010
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 190 ETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED 249
E+ ++PT E + P + + ++MG+ + V+G P+P+I W
Sbjct: 3565 ESPVYPTKFDSEK---EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQW-----F 3616
Query: 250 RENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
V++ P+ V + L+I +L+D G YTC A N G
Sbjct: 3617 FNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYG 3661
Score = 39.3 bits (90), Expect = 0.010
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 7/87 (8%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLV-IYNAQ 278
S+ GE + V+GRPRP I+W K E + R NV T + ++ I
Sbjct: 17950 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQT------TRVNVEETATSTVLHIKEGN 18003
Query: 279 LQDAGIYTCTARNVAGVLRADFPLSVV 305
D G YT TA N AG + + V+
Sbjct: 18004 KDDFGKYTVTATNSAGTATENLSVIVL 18030
Score = 38.9 bits (89), Expect = 0.013
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 6/100 (6%)
Query: 197 TASPETPELD--MAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVV 254
T P+ EL M AP + Q+V G F VVG+P PE W K E
Sbjct: 2017 TFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE--- 2073
Query: 255 MRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
R + + N+ +LVI + +D+ A N+AG
Sbjct: 2074 -RSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2112
Score = 38.5 bits (88), Expect = 0.017
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 203 PELDMAAPALLNNPVHQSVTM---GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNH 259
PELD+ ++Q + + G+ + V+GRP+P +TW+K + ++ +
Sbjct: 14691 PELDLRG-------IYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKK----GDQILKQTQR 14739
Query: 260 VRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
V T+ L I D+G Y TARN+ G
Sbjct: 14740 VNFETTATSTI-LNINECVRSDSGPYPLTARNIVG 14773
Score = 38.5 bits (88), Expect = 0.017
Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 22/135 (16%)
Query: 202 TPELDMAAPALLNNP--------VHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENV 253
T L++ PA ++ P VH GE VS G+P P ITW+K +++
Sbjct: 24642 TASLEVEVPAKIHLPKTLEGMGAVH--ALRGEVVSIKIPFSGKPDPVITWQK----GQDL 24695
Query: 254 VMRPNHVRGNVVVTNIAQLVIYN-AQLQDAGIYTCTARNVAGVLRADFPLSVV------R 306
+ H + +V + LV N + +DAG Y A+N G+ + L V R
Sbjct: 24696 IDNNGHYQ-VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPR 24754
Query: 307 GHQAAATSESSPNGT 321
G + + S S N T
Sbjct: 24755 GVKVSDVSRDSVNLT 24769
Score = 38.1 bits (87), Expect = 0.022
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 200 PETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNH 259
P ELD+ ++ +V +G+T+ L V GRP P+ITW K+ V++R
Sbjct: 11533 PPEVELDVTCRDVI------TVRVGQTIRILARVKGRPEPDITWTKE----GKVLVREKR 11582
Query: 260 VRGNVVVTNI--AQLVIYNAQLQDAGIYTCTARNVAG 294
V ++ ++ +L I A D G Y +A+N +G
Sbjct: 11583 VD---LIQDLPRVELQIKEAVRADHGKYIISAKNSSG 11616
Score = 38.1 bits (87), Expect = 0.022
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 13/78 (16%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVT-NIAQLVIYN 276
V GE + D+ GRP P I+W K ++E+R R ++ T N L + +
Sbjct: 19429 VKAGEVLKINADIAGRPLPVISWAKDGIEIEER---------ARTEIISTDNHTLLTVKD 19479
Query: 277 AQLQDAGIYTCTARNVAG 294
+D G Y T +NVAG
Sbjct: 19480 CIRRDTGQYVLTLKNVAG 19497
Score = 37.7 bits (86), Expect = 0.029
Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 12/95 (12%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
E PE+D+ A + V V G + V GRP P++TW K D NVV
Sbjct: 12230 EPPEIDLDAS--MRKLV--IVRAGCPIRLFAIVRGRPAPKVTWRKVGID--NVVR----- 12278
Query: 261 RGNV-VVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+G V +V +A LVI N+ D+G Y+ T N AG
Sbjct: 12279 KGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG 12313
Score = 37.7 bits (86), Expect = 0.029
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 3/79 (3%)
Query: 216 PVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIY 275
P S+ G+ ++ C G P PE+TW + H+ ++ L+I
Sbjct: 26963 PSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIEN---TDDLTTLIIM 27019
Query: 276 NAQLQDAGIYTCTARNVAG 294
+ Q QD G+YT + N G
Sbjct: 27020 DVQKQDGGLYTLSLGNEFG 27038
Score = 37.4 bits (85), Expect = 0.038
Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 16/114 (14%)
Query: 197 TASPETPELDMAAPALLNNPVHQS---VTMGETVSFLCDVVGRPRPEITW---EKQLEDR 250
+ P T + ++ P + +P + V GET DV G+P P I W +K++E+
Sbjct: 17238 STGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEES 17297
Query: 251 ENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
++ + A L++ +A D G Y A NVAG FP++V
Sbjct: 17298 ARCEIKNTDFK--------ALLIVKDAIRIDGGQYILRASNVAG--SKSFPVNV 17341
Score = 37.4 bits (85), Expect = 0.038
Identities = 33/111 (29%), Positives = 45/111 (40%), Gaps = 19/111 (17%)
Query: 190 ETTMHPTTASPE----TPELDMAAPALLNNPVHQSVTM--GETVSFLCDVVGRPRPEITW 243
E T P T PE PELD L++ + + + + G + GRP PEITW
Sbjct: 17633 EATSVPGTVKPEDKLEAPELD------LDSELRKGIVVRAGGSARIHIPFKGRPTPEITW 17686
Query: 244 EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
++ + + V V N QL I N DAG Y N +G
Sbjct: 17687 SREEGEFTDKVQIEKGV-------NYTQLSIDNCDRNDAGKYILKLENSSG 17730
Score = 37.0 bits (84), Expect = 0.049
Identities = 28/109 (25%), Positives = 42/109 (38%), Gaps = 5/109 (4%)
Query: 196 TTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVM 255
T S + + AAP + V +G F C++ P W K RE
Sbjct: 4448 TATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKA--GREIYES 4505
Query: 256 RPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
+R + +++ L I Q+ D G YTC A N G + L+V
Sbjct: 4506 DKCSIRSSKYISS---LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4551
Score = 37.0 bits (84), Expect = 0.049
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 14/120 (11%)
Query: 189 PETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITW---EK 245
P + P TA E M A + V + ++ L G PRP TW +K
Sbjct: 7005 PSEILGPLTADDAFVEPTMDLSAFKDG---LEVIVPNPITILVPSTGYPRPTATWCFGDK 7061
Query: 246 QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
LE + V M+ ++ A+LVI ++ D GIYT N + + ++V+
Sbjct: 7062 VLETGDRVKMK--------TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVI 7113
Score = 37.0 bits (84), Expect = 0.049
Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 11/77 (14%)
Query: 221 VTMGETVSFLCDVVGRPRPEITW---EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
V G V + + GRP P +W +L + E V + + T +A+L I
Sbjct: 23378 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH--------TKVAKLTIRET 23429
Query: 278 QLQDAGIYTCTARNVAG 294
++D G YT +NV G
Sbjct: 23430 TIRDTGEYTLELKNVTG 23446
Score = 36.6 bits (83), Expect = 0.065
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Query: 209 APALLNNPVHQ---SVTMGETVSF-LCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNV 264
AP ++ +P + ++ G+T+ ++G+P P+ +W K +D +RP+ +
Sbjct: 14003 APTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD-----IRPSDITQIT 14057
Query: 265 VVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ L I A +DAG YT TA N G
Sbjct: 14058 STPTSSMLTIKYATRKDAGEYTITATNPFG 14087
Score = 36.2 bits (82), Expect = 0.084
Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 6/103 (5%)
Query: 202 TPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVR 261
T + + P ++ P V GET F C V G P+P++ W N + R
Sbjct: 1787 TDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL------NGQLIRKSKR 1840
Query: 262 GNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
V I L I + + D G TA N GV+ L +
Sbjct: 1841 FRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 35.8 bits (81), Expect = 0.11
Identities = 28/79 (35%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN---HVRGNVVVTNIA--QLVIY 275
V GE V DV G P P+I W K E V+ +P + V + A +L I
Sbjct: 9038 VKAGEPVHIPADVTGLPMPKIEWSK----NETVIEKPTDALQITKEEVSRSEAKTELSIP 9093
Query: 276 NAQLQDAGIYTCTARNVAG 294
A +D G YT TA N G
Sbjct: 9094 KAVREDKGTYTVTASNRLG 9112
Score = 35.8 bits (81), Expect = 0.11
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 17/97 (17%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQ---LEDRENVVMRP 257
E PE+++ A + S T+ V+ + GRP PE+ WEK L DR +
Sbjct: 18731 EPPEIELDADLRKVVVLRASATLRLFVT----IKGRPEPEVKWEKAEGILTDRAQI---- 18782
Query: 258 NHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
V ++ LVI N D+G Y T N +G
Sbjct: 18783 ------EVTSSFTMLVIDNVTRFDSGRYNLTLENNSG 18813
Score = 35.8 bits (81), Expect = 0.11
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 17/97 (17%)
Query: 201 ETPELDMAAPALLNNPVHQSVTM--GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN 258
E P+L++A + + ++VT+ G ++ + V GRP P ITW KQ D +
Sbjct: 23070 EIPDLELA------DDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS------ 23117
Query: 259 HVRGNVVVT-NIAQLVIYNAQLQDAGIYTCTARNVAG 294
R + T + + L++ DAG YT A N +G
Sbjct: 23118 --RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSG 23152
Score = 35.0 bits (79), Expect = 0.19
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 15/96 (15%)
Query: 204 ELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEK-QLEDRENVVMRPNHVRG 262
+LD+ ++N + G ++ + GRP PE+ W K E R+ ++
Sbjct: 16571 DLDLELRKIIN------IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIID------ 16618
Query: 263 NVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRA 298
V ++ LV+ N D+G YT T N +G A
Sbjct: 16619 --VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSA 16652
Score = 34.7 bits (78), Expect = 0.25
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 9/94 (9%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
+ P LD+ +L +V G+T+ V G+P PE+ W K + + + R V
Sbjct: 11827 QKPVLDLKLSGVL------TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATD--LTRSPRV 11878
Query: 261 RGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ + + ++ + A+ D G Y TA N AG
Sbjct: 11879 KIDTRADS-SKFSLTKAKRSDGGKYVVTATNTAG 11911
Score = 34.7 bits (78), Expect = 0.25
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIA-QLVIYNAQLQDA 282
GE DV GRP P + W K ++ E + + + + + LV ++ +D+
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGT------AKLEIKIADFSTNLVNKDSTRRDS 15157
Query: 283 GIYTCTARNVAGVLRADFPLSVV 305
G YT TA N G + F + V+
Sbjct: 15158 GAYTLTATNPGGFAKHIFNVKVL 15180
Score = 34.3 bits (77), Expect = 0.32
Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 7/92 (7%)
Query: 206 DMAAPALLNNPVHQSVTM---GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRG 262
++ AP +P ++ V + GET D+ G+P P++ W K ++ E R ++
Sbjct: 18329 EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAAR-MEIKS 18387
Query: 263 NVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
+ T LV+ + D G Y NV G
Sbjct: 18388 TIQKTT---LVVKDCIRTDGGQYILKLSNVGG 18416
Score = 33.9 bits (76), Expect = 0.42
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 11/97 (11%)
Query: 201 ETPELDMAAPALLNNPVHQSVTM--GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPN 258
E E +MA L+ + +++ + G ++ + GRP PE+TW K + +N
Sbjct: 14394 EIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN------ 14447
Query: 259 HVRGNVVVT-NIAQLVIYNAQLQDAGIYTCTARNVAG 294
R N+ T + L+I D G + T N AG
Sbjct: 14448 --RANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 14482
Score = 33.9 bits (76), Expect = 0.42
Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 13/104 (12%)
Query: 203 PELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRG 262
PELD+ A N V G ++ GRP P W K + +R
Sbjct: 21983 PELDIDA----NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS--------LRA 22030
Query: 263 NVVVTN-IAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
++ T+ + L + N DAG YT T N +G F + V+
Sbjct: 22031 DIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVL 22074
Score = 33.9 bits (76), Expect = 0.42
Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 9/111 (8%)
Query: 198 ASPETPELDMA--APALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLED--RENV 253
+ P TP+ D+ AP + +V + +C V G P+P + W +Q ++ + +
Sbjct: 24542 SEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGL 24601
Query: 254 VMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSV 304
R +G QL+I + DA +Y A N G + L V
Sbjct: 24602 KYRIQEFKG-----GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24647
Score = 33.5 bits (75), Expect = 0.55
Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 14/67 (20%)
Query: 233 VVGRPRPEITWEKQLEDR-----ENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTC 287
VVG P P +TW K+ + ++ PN ++ + Q +D+G+Y C
Sbjct: 3723 VVGEPAPTVTWFKENKQLCTSVYYTIIHNPN---------GSGTFIVNDPQREDSGLYIC 3773
Query: 288 TARNVAG 294
A N+ G
Sbjct: 3774 KAENMLG 3780
Score = 33.5 bits (75), Expect = 0.55
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 19/121 (15%)
Query: 186 PPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEK 245
PPP ++T+ P LL N Q G++V F V G P P + WEK
Sbjct: 25414 PPPTDSTLRPMFKR------------LLANAECQE---GQSVCFEIRVSGIPPPTLKWEK 25458
Query: 246 QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
D + + + PN + + A L I + +D G Y TA N AG L V
Sbjct: 25459 ---DGQPLSLGPNIEIIHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514
Query: 306 R 306
R
Sbjct: 25515 R 25515
Score = 33.1 bits (74), Expect = 0.71
Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 15/124 (12%)
Query: 185 SPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWE 244
S P T + E PE+ + L +V G + V G+P P+ITW
Sbjct: 7298 SKPSRPTEEIQAVDTQEAPEIFLDVKLLAG----LTVKAGTKIELPATVTGKPEPKITWT 7353
Query: 245 KQLEDRENVVMRPNHVRGNVVVTNI---AQLVIYNAQLQDAGIYTCTARNVAGVLRADFP 301
K +++++ + + + N+ + + I +++ D G Y A NV G A
Sbjct: 7354 K-----ADMILKQDK---RITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVE 7405
Query: 302 LSVV 305
++V+
Sbjct: 7406 VNVL 7409
Score = 33.1 bits (74), Expect = 0.71
Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 202 TPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVR 261
+P+L + A VH G + + V G+P P +TW N+ R
Sbjct: 10149 SPDLQLDASVRDRIVVHA----GGVIRIIAYVSGKPPPTVTW--------NMNERTLPQE 10196
Query: 262 GNVVVTNIAQ-LVIYNAQLQDAGIYTCTARNVAG 294
+ T I+ +VI N Q G+Y+ A+N AG
Sbjct: 10197 ATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 10230
Score = 33.1 bits (74), Expect = 0.71
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
+V GE + +GRP P +TW K +NV ++ N + L I +A
Sbjct: 15786 TVLAGEDLKVDVPFIGRPTPAVTWHK-----DNVPLKQTTRVNAESTENNSLLTIKDACR 15840
Query: 280 QDAGIYTCTARNVAG 294
+D G Y N AG
Sbjct: 15841 EDVGHYVVKLTNSAG 15855
Score = 33.1 bits (74), Expect = 0.71
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 7/75 (9%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIA-QLVIYNAQL 279
V GE+ D+ G+P P I W K ++ N R + T+ A L + +A
Sbjct: 16183 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNT------ARLEIKSTDFATSLSVKDAVR 16236
Query: 280 QDAGIYTCTARNVAG 294
D+G Y A+NVAG
Sbjct: 16237 VDSGNYILKAKNVAG 16251
Score = 33.1 bits (74), Expect = 0.71
Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 9/94 (9%)
Query: 201 ETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHV 260
E PE+D+ AL + + ++ GE V L GRP P +TW K D +N+ +
Sbjct: 20895 EAPEIDLDV-ALRTSVIAKA---GEDVQVLIPFKGRPPPTVTWRK---DEKNLGSDARYS 20947
Query: 261 RGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAG 294
N +++ L I D G Y T N G
Sbjct: 20948 IENTDSSSL--LTIPQVTRNDTGKYILTIENGVG 20979
Score = 32.7 bits (73), Expect = 0.93
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 11/88 (12%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEK---QLEDRENVVMRPNHVRGNVVVTNIAQLVIYNA 277
V GE +S P P ++W K +++ + + M+ +H+ A L + +
Sbjct: 8026 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHIS--------AHLEVPKS 8077
Query: 278 QLQDAGIYTCTARNVAGVLRADFPLSVV 305
DAGIYT T N G A + V+
Sbjct: 8078 VRADAGIYTITLENKLGSATASINVKVI 8105
Score = 32.7 bits (73), Expect = 0.93
Identities = 21/85 (24%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 210 PALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI 269
P + P ++ G+ + V G+P P W+K E+ V+ +H+ + ++
Sbjct: 12527 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKG----EDEVVTSSHLAVHKADSS- 12581
Query: 270 AQLVIYNAQLQDAGIYTCTARNVAG 294
+ L+I + +D+G Y+ TA N +G
Sbjct: 12582 SILIIKDVTRKDSGYYSLTAENSSG 12606
Score = 32.3 bits (72), Expect = 1.2
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 220 SVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVT-NIAQLVIYNAQ 278
SV +G+ + + GRP+P ITW K + + ++ R NV + ++ L I
Sbjct: 16868 SVQVGQDLKIEVPISGRPKPTITWTK-----DGLPLKQT-TRINVTDSLDLTTLSIKETH 16921
Query: 279 LQDAGIYTCTARNVAG 294
D G Y T NV G
Sbjct: 16922 KDDGGQYGITVANVVG 16937
Score = 32.3 bits (72), Expect = 1.2
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAG 283
G +V + G+P P I W K +D+E ++ N + T++A ++I +A ++G
Sbjct: 20515 GTSVKLRAGISGKPAPTIEWYK--DDKE---LQTNALVCVENTTDLASILIKDADRLNSG 20569
Query: 284 IYTCTARNVAGVLRADFPLSVV 305
Y RN G A + ++
Sbjct: 20570 CYELKLRNAMGSASATIRVQIL 20591
Score = 32.0 bits (71), Expect = 1.6
Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 9/135 (6%)
Query: 171 AVVTCRYHFTWPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTM-GETVSF 229
AV TC + + + P SP+ E+ + PA++ P+ +VT G+ F
Sbjct: 3261 AVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ-EMPVYPPAIIT-PLQDTVTSEGQPARF 3318
Query: 230 LCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTA 289
C V G +++W + D++ ++P+ + QL I A +D G YT A
Sbjct: 3319 QCRVSGTDL-KVSWYSK--DKK---IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA 3372
Query: 290 RNVAGVLRADFPLSV 304
N G + + LS+
Sbjct: 3373 SNAVGQVSSTANLSL 3387
Score = 31.6 bits (70), Expect = 2.1
Identities = 58/237 (24%), Positives = 92/237 (38%), Gaps = 37/237 (15%)
Query: 117 LQQGS------ECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRC----YMDAEACSK 166
+QQG+ E D + G + E E + +++ ++Y+N Y+DA +K
Sbjct: 4257 IQQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTK 4316
Query: 167 GITLAVVTCRYHFTWPNTSPPPPETTMHPTTASPETPELDMAAPALLNNP---VHQSVTM 223
G+ AVV+ S E++ T T ++ A L+ +H +
Sbjct: 4317 GVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLV- 4375
Query: 224 GETVSFLCDVVGRPRPEITWEKQLE-DRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQD- 281
+TVS D+V IT K++ EN ++ + + N LVI +D
Sbjct: 4376 -DTVSEEGDIV-HLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4433
Query: 282 AGIYTCTARNVAG-----------------VLRADFPLSVVRGHQAAATSE--SSPN 319
G Y C A N +G + R PL V GH A T E S+PN
Sbjct: 4434 QGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPN 4490
Score = 31.6 bits (70), Expect = 2.1
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 15/106 (14%)
Query: 202 TPELDMAAPALLNNPVHQ-SVTMGETVSFLCDVVGRPRPEITWEKQ-LEDRENVVMRPNH 259
TPE+D++ + P Q +V +G V G+P+P I+W K L +E+ +R +
Sbjct: 21188 TPEVDLS-----DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSK 21242
Query: 260 VRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVV 305
+ L I NA+ + G YT N V R P++V+
Sbjct: 21243 TENKIT------LSIKNAKKEHGGKYTVILDN--AVCRIAVPITVI 21280
Score = 31.6 bits (70), Expect = 2.1
Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 15/98 (15%)
Query: 203 PELDMAAPALLNNPVHQSVTMGETVSFLCDVV--GRPRPEITW---EKQLEDRENVVMRP 257
P+++ A L +Q +T F DV GRP P++TW E +L++ + V +
Sbjct: 22269 PQIEPTAD--LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT 22326
Query: 258 NHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGV 295
R L + ++ D+G Y T N AGV
Sbjct: 22327 TKDR--------TTLTVKDSMRGDSGRYFLTLENTAGV 22356
Score = 31.2 bits (69), Expect = 2.7
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 215 NPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVI 274
N + V+ +T+ +C+V +P E+ W K E+ G + LVI
Sbjct: 6096 NLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRI-----LVI 6149
Query: 275 YNAQLQDAGIYTC 287
NA L+DAG Y C
Sbjct: 6150 QNAHLEDAGNYNC 6162
Score = 30.8 bits (68), Expect = 3.5
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 223 MGETVSFLCDVVGRPRPEITW---EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQL 279
+G T+ +GRP P +TW +K L++ EN+ + ++V+ N+ +
Sbjct: 24270 VGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKT------ 24323
Query: 280 QDAGIYTCTARNVAGVLRA 298
AG Y NV G + A
Sbjct: 24324 -HAGKYKVQLSNVFGTVDA 24341
Score = 30.0 bits (66), Expect = 6.0
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 224 GETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAG 283
G V+F C + G P P+I W K + + + + A L I +D G
Sbjct: 1259 GMGVTFHCKMSGYPLPKIAWYKD----GKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1314
Query: 284 IYTCTARNVAG 294
IYT A N+ G
Sbjct: 1315 IYTAFASNIKG 1325
Score = 30.0 bits (66), Expect = 6.0
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 17/129 (13%)
Query: 185 SPPPPETTMHPTTASPETPE--LDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEIT 242
S P T P T E PE +D+ A L G + + GRP P+ +
Sbjct: 9418 SEPSDTTGEIPATDIQEEPEVFIDIGAQDCL------VCKAGSQIRIPAVIKGRPTPKSS 9471
Query: 243 WE------KQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVL 296
WE K ++D + + + N + ++I + G Y+ TA+N AG
Sbjct: 9472 WEFDGKAKKAMKDGVHDIPEDAQLE---TAENSSVIIIPECKRSHTGKYSITAKNKAGQK 9528
Query: 297 RADFPLSVV 305
A+ + V+
Sbjct: 9529 TANCRVKVM 9537
Score = 30.0 bits (66), Expect = 6.0
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 9/73 (12%)
Query: 221 VTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNI-AQLVIYNAQL 279
V G + + GRP P + W K D R V T+ L I NA
Sbjct: 19826 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRT--------RAYVDTTDSRTSLTIENANR 19877
Query: 280 QDAGIYTCTARNV 292
D+G YT T +NV
Sbjct: 19878 NDSGKYTLTIQNV 19890
Score = 29.6 bits (65), Expect = 7.9
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 11/65 (16%)
Query: 233 VVGRPRPEITW---EKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTA 289
V G+P P+I W +K+L+ E V ++ R A VI D+G YT T
Sbjct: 22699 VGGKPEPKIIWTKGDKELDLCEKVSLQYTGKR--------ATAVIKFCDRSDSGKYTLTV 22750
Query: 290 RNVAG 294
+N +G
Sbjct: 22751 KNASG 22755
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,657,125
Number of Sequences: 37866
Number of extensions: 1356740
Number of successful extensions: 7367
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 176
Number of HSP's that attempted gapping in prelim test: 4995
Number of HSP's gapped (non-prelim): 1828
length of query: 576
length of database: 18,247,518
effective HSP length: 108
effective length of query: 468
effective length of database: 14,157,990
effective search space: 6625939320
effective search space used: 6625939320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.