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Search of human proteins with 27735137
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27735137 solute carrier family 38, member 11 [Homo sapiens]
(384 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27735137 solute carrier family 38, member 11 [Homo sapiens] 769 0.0
gi|117168277 amino acid transporter system A1 [Homo sapiens] 105 9e-23
gi|117168275 amino acid transporter system A1 [Homo sapiens] 105 9e-23
gi|193788624 solute carrier family 38, member 5 [Homo sapiens] 102 4e-22
gi|5870893 solute carrier family 38, member 3 [Homo sapiens] 101 1e-21
gi|24429574 solute carrier family 38, member 6 [Homo sapiens] 97 2e-20
gi|21361602 solute carrier family 38, member 2 [Homo sapiens] 96 4e-20
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 86 4e-17
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ... 86 4e-17
gi|8922692 solute carrier family 38, member 7 [Homo sapiens] 81 2e-15
gi|219689132 solute carrier family 38, member 4 [Homo sapiens] 79 5e-15
gi|18482385 solute carrier family 38, member 4 [Homo sapiens] 79 5e-15
gi|122937281 solute carrier family 38, member 8 [Homo sapiens] 73 4e-13
gi|222418629 solute carrier family 38, member 9 [Homo sapiens] 58 1e-08
gi|41352721 solute carrier family 36 member 1 [Homo sapiens] 53 5e-07
gi|40807351 solute carrier family 36 (proton/amino acid symporte... 39 0.010
gi|12232393 major facilitator superfamily domain containing 1 [H... 32 0.96
gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9... 31 1.6
gi|4503635 coagulation factor II preproprotein [Homo sapiens] 30 3.7
gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-... 30 3.7
>gi|27735137 solute carrier family 38, member 11 [Homo sapiens]
Length = 384
Score = 769 bits (1987), Expect = 0.0
Identities = 384/384 (100%), Positives = 384/384 (100%)
Query: 1 MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQF 60
MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQF
Sbjct: 1 MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQF 60
Query: 61 LYPFIVDPENVFIGRHFIIGLSTVTFTLPLSLYRNIAKLGKVSLISTGLTTLILGIVMAR 120
LYPFIVDPENVFIGRHFIIGLSTVTFTLPLSLYRNIAKLGKVSLISTGLTTLILGIVMAR
Sbjct: 61 LYPFIVDPENVFIGRHFIIGLSTVTFTLPLSLYRNIAKLGKVSLISTGLTTLILGIVMAR 120
Query: 121 AISLGPHIPKTEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHM 180
AISLGPHIPKTEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHM
Sbjct: 121 AISLGPHIPKTEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHM 180
Query: 181 SIVISVFICIFFATCGYLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPMECFV 240
SIVISVFICIFFATCGYLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPMECFV
Sbjct: 181 SIVISVFICIFFATCGYLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPMECFV 240
Query: 241 TREVIANVFFGGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIP 300
TREVIANVFFGGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIP
Sbjct: 241 TREVIANVFFGGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIP 300
Query: 301 SACYLKLSEEPRTHSDKIMSCVMLPIGAVVMVFGFVMAITNTQDCTHGQEMFYCFPDNFS 360
SACYLKLSEEPRTHSDKIMSCVMLPIGAVVMVFGFVMAITNTQDCTHGQEMFYCFPDNFS
Sbjct: 301 SACYLKLSEEPRTHSDKIMSCVMLPIGAVVMVFGFVMAITNTQDCTHGQEMFYCFPDNFS 360
Query: 361 LTNTSESHVQQTTQLSTLNISIFQ 384
LTNTSESHVQQTTQLSTLNISIFQ
Sbjct: 361 LTNTSESHVQQTTQLSTLNISIFQ 384
>gi|117168277 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 105 bits (261), Expect = 9e-23
Identities = 89/379 (23%), Positives = 163/379 (43%), Gaps = 40/379 (10%)
Query: 1 MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLL----- 55
+ G L ++LL V+ ++ +S+ LL+ +G Y+ L + FG G ++
Sbjct: 96 LANTGILLFLVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATS 155
Query: 56 -----SVLQFLY----------PFIVDPENVF----IGRHFIIGLSTVTFTLPLSLYRNI 96
++L +L+ F++ E F + ++ + T LPL L +N+
Sbjct: 156 LQNTGAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNL 215
Query: 97 AKLGKVSLISTGLTTLILGIVMARAISLGPHIPKTEDA--------------WVFAKPNA 142
LG S S L +V+ + + +P+ +V
Sbjct: 216 GYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSKT 275
Query: 143 IQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTG 202
+ A+ ++FAF+CH + +YS L++ + K + ++S + A GYLTF
Sbjct: 276 VYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYD 335
Query: 203 FTQGDLFENYCRNDD-LVTFGRFCYGVTVILTYPMECFVTREVIANVFFGGNLSSVFHIV 261
Q DL Y DD L+ R V VILT P+ F R + + + H V
Sbjct: 336 NVQSDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFNLCRHTV 395
Query: 262 VTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKLSEEPRTH-SDKIMS 320
VT +++ V L+ + I + + + GV A LIFI+PS+ YLK++++ + +I +
Sbjct: 396 VTCILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWA 455
Query: 321 CVMLPIGAVVMVFGFVMAI 339
+ L +G + + + I
Sbjct: 456 ALFLGLGVLFSLVSIPLVI 474
>gi|117168275 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 105 bits (261), Expect = 9e-23
Identities = 89/379 (23%), Positives = 163/379 (43%), Gaps = 40/379 (10%)
Query: 1 MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLL----- 55
+ G L ++LL V+ ++ +S+ LL+ +G Y+ L + FG G ++
Sbjct: 96 LANTGILLFLVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATS 155
Query: 56 -----SVLQFLY----------PFIVDPENVF----IGRHFIIGLSTVTFTLPLSLYRNI 96
++L +L+ F++ E F + ++ + T LPL L +N+
Sbjct: 156 LQNTGAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNL 215
Query: 97 AKLGKVSLISTGLTTLILGIVMARAISLGPHIPKTEDA--------------WVFAKPNA 142
LG S S L +V+ + + +P+ +V
Sbjct: 216 GYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSKT 275
Query: 143 IQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTG 202
+ A+ ++FAF+CH + +YS L++ + K + ++S + A GYLTF
Sbjct: 276 VYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYD 335
Query: 203 FTQGDLFENYCRNDD-LVTFGRFCYGVTVILTYPMECFVTREVIANVFFGGNLSSVFHIV 261
Q DL Y DD L+ R V VILT P+ F R + + + H V
Sbjct: 336 NVQSDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFNLCRHTV 395
Query: 262 VTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKLSEEPRTH-SDKIMS 320
VT +++ V L+ + I + + + GV A LIFI+PS+ YLK++++ + +I +
Sbjct: 396 VTCILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWA 455
Query: 321 CVMLPIGAVVMVFGFVMAI 339
+ L +G + + + I
Sbjct: 456 ALFLGLGVLFSLVSIPLVI 474
>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
Length = 472
Score = 102 bits (255), Expect = 4e-22
Identities = 97/390 (24%), Positives = 171/390 (43%), Gaps = 54/390 (13%)
Query: 1 MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQF 60
M G + LL ++ ++ +S+ LL+ ++G Y+ L + FG G ++++ +
Sbjct: 73 MAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFGPAGKVVVATVIC 132
Query: 61 L--------YPFIV--------------DPE-NVFIGRHFIIGLSTVTFTLPLSLYRNIA 97
L Y FI+ DPE + F+ + +I + +V LPL+L +++
Sbjct: 133 LHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLIIIVSVLIILPLALMKHLG 192
Query: 98 KLGKVSLISTGLTTLILGIVMARAISLGPHIPKTE--------------------DAWVF 137
LG S +S L V+ + LG I E +A +F
Sbjct: 193 YLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMF 252
Query: 138 AKPNAIQ-AVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCG 196
+ + V +M+FAF+CH +Y+ L P+ + + ++SI + AT G
Sbjct: 253 TVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFG 312
Query: 197 YLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPMECFVTREVIANVFFGGNLSS 256
YLTF + ++ Y + D L+ R + V LT P+ F R + + F G S
Sbjct: 313 YLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFS 372
Query: 257 VFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCAT---PLIFIIPSACYLKL---SEE 310
V +++ V LV++L+ C+ + ++ GV+ +T LIFI+PS YL++ E
Sbjct: 373 WPRHVAIALILLV--LVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVE 430
Query: 311 PRTHSDKIMSCVMLPIGAVVMV--FGFVMA 338
P KI + +G + M GF+ A
Sbjct: 431 PFLSWPKIQALCFGVLGVLFMAVSLGFMFA 460
>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
Length = 504
Score = 101 bits (252), Expect = 1e-21
Identities = 95/403 (23%), Positives = 167/403 (41%), Gaps = 67/403 (16%)
Query: 1 MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQF 60
M G L + LL V+ ++ +S+ LL+K + G Y+ L + FG PG L ++
Sbjct: 91 MANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIRAYEQLGYRAFGTPGKLAAALAIT 150
Query: 61 L--------YPFIVDPE----------------NVFIGRHFIIGLSTVTFTLPLSLYRNI 96
L Y +I+ E + ++ ++++ L +VT LPL+L R +
Sbjct: 151 LQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQL 210
Query: 97 AKLGKVSLISTGLTTLILGIVMARAISLGPHIPKT-----------------------ED 133
LG S S L V+ + + +P +
Sbjct: 211 GYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPE 270
Query: 134 AWVFAKPN-------AIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISV 186
A F P+ + +M+FAF+CH +Y+ L++P+ K + ++SI +
Sbjct: 271 ASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMY 330
Query: 187 FICIFFATCGYLTFTGFTQGDLFENYCRNDD---LVTFGRFCYGVTVILTYPMECFVTRE 243
+ A GYLTF + +L Y + D L+ R V LT P+ F R
Sbjct: 331 IMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRR 390
Query: 244 VIANVFF-GGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATP---LIFII 299
I + F S + H+++ V ++ T ++LL+ +L + GV+ AT LIFI
Sbjct: 391 AIQQMLFPNQEFSWLRHVLIAVGLL---TCINLLVIFAPNILGIFGVIGATSAPFLIFIF 447
Query: 300 PSACYLKL---SEEPRTHSDKIMSCVMLPIGAVVMVFGFVMAI 339
P+ Y ++ +EP + KI++ +G ++M I
Sbjct: 448 PAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSLSFII 490
>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
Length = 456
Score = 97.1 bits (240), Expect = 2e-20
Identities = 92/371 (24%), Positives = 161/371 (43%), Gaps = 44/371 (11%)
Query: 12 LLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLS---VLQFL-----YP 63
LL V+ + +S+ LL+ + +Y+ L FG PG L+++ ++Q + Y
Sbjct: 81 LLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYL 140
Query: 64 FIVDPENVFIGRHFIIG---------------LSTVTFTLPLSLYRNIAKLGKVSLISTG 108
I+ E F+ G + V PL+L I LG S +S
Sbjct: 141 LIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFF 200
Query: 109 LTTLILGIVMARAISL-----------GPHIPKTED-----AWVFAKPNAIQAVGVMSFA 152
+V+ + S+ G I D + F+K +A A+ M+F+
Sbjct: 201 FMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKPKLFHFSKESAY-ALPTMAFS 259
Query: 153 FICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTGFTQGDLFENY 212
F+CH + +Y L+ P+ + + + +I +S I A GYLTF + +L + Y
Sbjct: 260 FLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGY 319
Query: 213 CR---NDDLVTFGRFCYGVTVILTYPMECFVTREVIANVFFGG-NLSSVFHIVVTVMVIT 268
+ +D +V + C V+LT P+ F R+ + +FF S + H ++T+ +
Sbjct: 320 SKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNI 379
Query: 269 VATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKLSEEPRTHSDKIMSCVMLPIGA 328
+ L+++ + + V + G +T LIFI P YLKLS E K+ + V+L G
Sbjct: 380 IIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGAFVLLIFGI 439
Query: 329 VVMVFGFVMAI 339
+V F + I
Sbjct: 440 LVGNFSLALII 450
>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
Length = 506
Score = 96.3 bits (238), Expect = 4e-20
Identities = 89/399 (22%), Positives = 164/399 (41%), Gaps = 60/399 (15%)
Query: 1 MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLS---- 56
M G L I+LL +VS + +S+ LL+K G+ Y+ L K FG G L S
Sbjct: 96 MANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSIT 155
Query: 57 ------------VLQFLYPFIVDP-ENV-------FIGRHFIIGLSTVTFTLPLSLYRNI 96
++++ P ++ N+ ++ ++++ L ++ LPLSL+RN+
Sbjct: 156 MQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNL 215
Query: 97 AKLGKVSLISTGLTTLILGIVMARAI----------------------------SLGPHI 128
LG S +S L +V+ + +L ++
Sbjct: 216 GYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNV 275
Query: 129 PKTEDA---WVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVIS 185
+ + + + AV ++ F+F+CH +Y L++ + + + +S
Sbjct: 276 TENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAM 335
Query: 186 VFICIFFATCGYLTFTGFTQGDLFENYCR---NDDLVTFGRFCYGVTVILTYPMECFVTR 242
+ + A GYLTF + +L Y D L+ R + V LT P+ F R
Sbjct: 336 FLMYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIR 395
Query: 243 EVIANVFFGGNLSSVF-HIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPS 301
+ ++ S + H ++TV ++ L+ + + + + G A+ LIFI+PS
Sbjct: 396 SSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPS 455
Query: 302 ACYLKL-SEEPRTHSDKIMSCVMLPIGAVVMVFGFVMAI 339
A Y+KL +EP KI + L G +VM + +
Sbjct: 456 AFYIKLVKKEPMKSVQKIGALFFLLSGVLVMTGSMALIV 494
>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
sapiens]
Length = 1119
Score = 86.3 bits (212), Expect = 4e-17
Identities = 85/377 (22%), Positives = 161/377 (42%), Gaps = 42/377 (11%)
Query: 2 KQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQF- 60
KQ G LG LLL + S++T S + L+K +LS TY L +G G +L+
Sbjct: 32 KQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIG 91
Query: 61 --------LYPFIVDPENVFIG-----------RHFIIGLSTVTFTLPLSLYRN-IAKLG 100
Y I D + F R F++ ++ LPLSL RN +A +
Sbjct: 92 LMLGTCIAFYVVIGDLGSNFFARLFGFQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQ 151
Query: 101 KVSLISTGLTTLILGIVMARAISLGPHIPKTEDAWVFAK-PNAIQAVGVMSFAFICHHNS 159
S ++ T+ + +++ ++ G + + + + + + +F C
Sbjct: 152 SFSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQV 211
Query: 160 FLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTGFTQGDLFENYCRNDDLV 219
Y SL+EP+V S + S+ + + GY++FT T G++ ++ N LV
Sbjct: 212 LPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSN--LV 269
Query: 220 T-FGRFCYGVTVILTYPMECFVTREVIANVF-----------FGGNLSSVFHIVVTVMVI 267
T R + ++V + +PM R+ ++ + GG + + +T+ V+
Sbjct: 270 TEMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVV 329
Query: 268 TVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKLSEEPRTHSDKIMSCVMLPIG 327
+ +LI + +L L G + + FI P+ Y K+ H + + S V+L +G
Sbjct: 330 FGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKI------HKNALSSQVVLWVG 383
Query: 328 AVVMVFGFVMAITNTQD 344
V+V V ++ +++
Sbjct: 384 LGVLVVSTVTTLSVSEE 400
>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
sapiens]
Length = 780
Score = 86.3 bits (212), Expect = 4e-17
Identities = 85/377 (22%), Positives = 161/377 (42%), Gaps = 42/377 (11%)
Query: 2 KQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQF- 60
KQ G LG LLL + S++T S + L+K +LS TY L +G G +L+
Sbjct: 32 KQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIG 91
Query: 61 --------LYPFIVDPENVFIG-----------RHFIIGLSTVTFTLPLSLYRN-IAKLG 100
Y I D + F R F++ ++ LPLSL RN +A +
Sbjct: 92 LMLGTCIAFYVVIGDLGSNFFARLFGFQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQ 151
Query: 101 KVSLISTGLTTLILGIVMARAISLGPHIPKTEDAWVFAK-PNAIQAVGVMSFAFICHHNS 159
S ++ T+ + +++ ++ G + + + + + + +F C
Sbjct: 152 SFSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQV 211
Query: 160 FLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTGFTQGDLFENYCRNDDLV 219
Y SL+EP+V S + S+ + + GY++FT T G++ ++ N LV
Sbjct: 212 LPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSN--LV 269
Query: 220 T-FGRFCYGVTVILTYPMECFVTREVIANVF-----------FGGNLSSVFHIVVTVMVI 267
T R + ++V + +PM R+ ++ + GG + + +T+ V+
Sbjct: 270 TEMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVV 329
Query: 268 TVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKLSEEPRTHSDKIMSCVMLPIG 327
+ +LI + +L L G + + FI P+ Y K+ H + + S V+L +G
Sbjct: 330 FGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKI------HKNALSSQVVLWVG 383
Query: 328 AVVMVFGFVMAITNTQD 344
V+V V ++ +++
Sbjct: 384 LGVLVVSTVTTLSVSEE 400
>gi|8922692 solute carrier family 38, member 7 [Homo sapiens]
Length = 462
Score = 80.9 bits (198), Expect = 2e-15
Identities = 69/253 (27%), Positives = 116/253 (45%), Gaps = 19/253 (7%)
Query: 72 FIGRHFIIGLSTVTFTLPLSLYRNIAKLGKVSLISTGLTTLILGIVMARAI----SLGPH 127
+ R F I L+ F LPLS+ R I S +S T + IV+ + I + P
Sbjct: 173 YTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPG 232
Query: 128 IPKTEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVF 187
T A A NA+ + F F CH +S V++S+++P V W ++ ++VI++
Sbjct: 233 NILTRPASWMAVFNAMPTI---CFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALA 289
Query: 188 ICIFFATCGYLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPMECFVTREVIAN 247
+ + CG+LTF D+ +Y D V R ++V+ +YP+ F R V+
Sbjct: 290 VYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEG 349
Query: 248 VFFGGNLSSV---------FHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFI 298
++ V ++ T++ + L++L I +G V+ + G L A IF+
Sbjct: 350 LWLRYQGVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAAC-FIFV 408
Query: 299 IPSACYL--KLSE 309
P C + KLSE
Sbjct: 409 FPGLCLIQAKLSE 421
>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 79.3 bits (194), Expect = 5e-15
Identities = 57/215 (26%), Positives = 100/215 (46%), Gaps = 5/215 (2%)
Query: 130 KTEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFIC 189
K E + A+ ++ FAF+CH +YS L++ + K + ++SI + +
Sbjct: 320 KCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMY 379
Query: 190 IFFATCGYLTFTGFTQGDLFENYCR---NDDLVTFGRFCYGVTVILTYPMECFVTR-EVI 245
+ A GYLTF G + +L Y + D + R V V LT P+ F R VI
Sbjct: 380 LLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVI 439
Query: 246 ANVFFGGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYL 305
+F S + H ++ ++I + ++ +L+ + + G AT LIFI+P+ YL
Sbjct: 440 TLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYL 499
Query: 306 KLSEEPRTHS-DKIMSCVMLPIGAVVMVFGFVMAI 339
KL ++ S K+ + + L +G M+ + I
Sbjct: 500 KLVKKETFRSPQKVGALIFLVVGIFFMIGSMALII 534
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/153 (23%), Positives = 68/153 (44%), Gaps = 24/153 (15%)
Query: 1 MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYL------- 53
M G L I++L V+ ++ +S+ LL+K G+ Y+ L K FG+PG +
Sbjct: 100 MANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSIT 159
Query: 54 ---------LLSVLQFLYPFIVD-----PENV---FIGRHFIIGLSTVTFTLPLSLYRNI 96
L ++++ P ++ EN ++ +++I +V LPLSL +N+
Sbjct: 160 MQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNL 219
Query: 97 AKLGKVSLISTGLTTLILGIVMARAISLGPHIP 129
LG S S + +V+ + + +P
Sbjct: 220 GYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLP 252
>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 79.3 bits (194), Expect = 5e-15
Identities = 57/215 (26%), Positives = 100/215 (46%), Gaps = 5/215 (2%)
Query: 130 KTEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFIC 189
K E + A+ ++ FAF+CH +YS L++ + K + ++SI + +
Sbjct: 320 KCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMY 379
Query: 190 IFFATCGYLTFTGFTQGDLFENYCR---NDDLVTFGRFCYGVTVILTYPMECFVTR-EVI 245
+ A GYLTF G + +L Y + D + R V V LT P+ F R VI
Sbjct: 380 LLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVI 439
Query: 246 ANVFFGGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYL 305
+F S + H ++ ++I + ++ +L+ + + G AT LIFI+P+ YL
Sbjct: 440 TLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYL 499
Query: 306 KLSEEPRTHS-DKIMSCVMLPIGAVVMVFGFVMAI 339
KL ++ S K+ + + L +G M+ + I
Sbjct: 500 KLVKKETFRSPQKVGALIFLVVGIFFMIGSMALII 534
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/153 (23%), Positives = 68/153 (44%), Gaps = 24/153 (15%)
Query: 1 MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYL------- 53
M G L I++L V+ ++ +S+ LL+K G+ Y+ L K FG+PG +
Sbjct: 100 MANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSIT 159
Query: 54 ---------LLSVLQFLYPFIVD-----PENV---FIGRHFIIGLSTVTFTLPLSLYRNI 96
L ++++ P ++ EN ++ +++I +V LPLSL +N+
Sbjct: 160 MQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNL 219
Query: 97 AKLGKVSLISTGLTTLILGIVMARAISLGPHIP 129
LG S S + +V+ + + +P
Sbjct: 220 GYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLP 252
>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
Length = 435
Score = 73.2 bits (178), Expect = 4e-13
Identities = 80/348 (22%), Positives = 141/348 (40%), Gaps = 60/348 (17%)
Query: 9 GILLLFWVSYVTDFSLVLLIKG-------GALSGTDTYQSLVNKTFG------FPGYLLL 55
G++ F V V SLV LI G A+SG TYQ +V G LL
Sbjct: 54 GVVPAFLVELV---SLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLL 110
Query: 56 SVLQFLYPFI-------------------VDPENVFIGRHFIIGLSTVTFTLPLSLYRNI 96
++L F+ P+ + + F + L +V LPLS R I
Sbjct: 111 NLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREI 170
Query: 97 AKLGKVSLISTGLTTLILGIVMARAISLGP-------HIPKTEDAWVFAKPNAIQAVGVM 149
A S++ T L L +V+ L P H + +W + +
Sbjct: 171 AFQKYTSILGT-LAACYLALVITVQYYLWPQGLVRESHPSLSPASWT----SVFSVFPTI 225
Query: 150 SFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTGFTQGDLF 209
F F CH + +Y S+ + +++ W+ + +S++ I G+LTF D+
Sbjct: 226 CFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVL 285
Query: 210 ENYCRNDDLVTFGRFCYGVTVILTYPMECFVTREVIANVF----FGGNLSSVF------- 258
+Y ND ++ R + V+++ YP+ F+ R V+ + + GG S
Sbjct: 286 MSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLW 345
Query: 259 -HIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYL 305
+ +T++ +TV ++L + L ++ + G + ++ IFI P C +
Sbjct: 346 VRMPLTILWVTVTLAMALFMPDLSEIVSIIGGI-SSFFIFIFPGLCLI 392
>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
Length = 561
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/274 (19%), Positives = 112/274 (40%), Gaps = 28/274 (10%)
Query: 84 VTFTLPLSLYRNIAKLGKVSLISTGLTTLILGIVMARAISLGPHIPKTEDAWVFAKPNAI 143
V LPL +++ + K +++ T ++ +V +A+ LG H+ E W +
Sbjct: 296 VGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFLVTFKAVRLGFHL---EFHWFIPTEFFV 352
Query: 144 --------QAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATC 195
Q GV++ AF H+ + + + K + + + + + +
Sbjct: 353 PEIRFQFPQLTGVLTLAFFIHNCIITLLKNNK-----KQENNVRDLCIAYMLVTLTYLYI 407
Query: 196 GYLTFTGFTQGDL---------FENYCRNDDLVTFGRFCYGVTVILTYPMECFVTREVIA 246
G L F F L +N+ +D L R ++ YP+ ++ R +
Sbjct: 408 GVLVFASFPSPPLSKDCIEQNFLDNFPSSDTLSFIARIFLLFQMMTVYPLLGYLARVQLL 467
Query: 247 NVFFGGNLSSVFHI-VVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACY- 304
FG S+FH+ ++ ++++ +++ +G ++ +G C +FI PS Y
Sbjct: 468 GHIFGDIYPSIFHVLILNLIIVGAGVIMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYI 527
Query: 305 LKLSEEPRTHSDKIMSCVMLPI-GAVVMVFGFVM 337
+ L +E R K++ V + I G ++ F M
Sbjct: 528 ISLHQEERLTWPKLIFHVFIIILGVANLIVQFFM 561
>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
Length = 476
Score = 52.8 bits (125), Expect = 5e-07
Identities = 60/280 (21%), Positives = 121/280 (43%), Gaps = 34/280 (12%)
Query: 81 LSTVTFTLPLSLYRNIAKLGKVSLISTGLTTLILGIVM-----ARAISLGPHIP-----K 130
LS + F + L RN+ L SL++ T+++ +VM + I H+P K
Sbjct: 199 LSFLPFLVLLVFIRNLRALSIFSLLAN--ITMLVSLVMIYQFIVQRIPDPSHLPLVAPWK 256
Query: 131 TEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICI 190
T + + + +G++ + + +++P K+ ++++ +VI + I
Sbjct: 257 TYPLFFGTAIFSFEGIGMV----------LPLENKMKDPR--KFPLILYLGMVIVTILYI 304
Query: 191 FFATCGYLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPMECFVTREVIANVFF 250
GYL F QG + N N L + Y + + TY ++ +V E+I F
Sbjct: 305 SLGCLGYLQFGANIQGSITLN-LPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFV 363
Query: 251 G---GNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKL 307
+ V + V +++ + ++++LI L +V+ L G + ++ L IIP
Sbjct: 364 SRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLL---- 419
Query: 308 SEEPRTHSDKIMSCVMLPIGAVVMVFGFVMAITNTQDCTH 347
E T + MS + + A++ + GFV + T + +
Sbjct: 420 --EVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALY 457
>gi|40807351 solute carrier family 36 (proton/amino acid symporter),
member 4 [Homo sapiens]
Length = 504
Score = 38.5 bits (88), Expect = 0.010
Identities = 28/126 (22%), Positives = 58/126 (46%), Gaps = 5/126 (3%)
Query: 178 IHMSIVISVFICIFFATCGYLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPME 237
I M IV ++++ + AT GY+ F +G + N ++ L + Y + +TY ++
Sbjct: 309 IGMGIVTTLYVTL--ATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQ 366
Query: 238 CFVTREVI---ANVFFGGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATP 294
+V E+I F + + ++++ ++LI L IV+ G + ++
Sbjct: 367 FYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSST 426
Query: 295 LIFIIP 300
L I+P
Sbjct: 427 LALILP 432
>gi|12232393 major facilitator superfamily domain containing 1 [Homo
sapiens]
Length = 465
Score = 32.0 bits (71), Expect = 0.96
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 30/151 (19%)
Query: 181 SIVISVFICIFFATCGYLTFTGFTQGDLFENYCRNDDLVTFGRFCYGV------TVILTY 234
+I+ S F+CI G + F G +F + L+ FGRF +G+ TY
Sbjct: 113 TIIFSCFVCI-----GQVVFA---LGGIFNAFW----LMEFGRFVFGIGGESLAVAQNTY 160
Query: 235 PMECFVTREVIANVFFGGNLSSVFHIVVTVMVITVATLVSLLI--------DCLGIVLEL 286
+ F +E+ N+ FG LS I TV + + L S + LGI L +
Sbjct: 161 AVSWFKGKEL--NLVFGLQLSMA-RIGSTVNMNLMGWLYSKIEALLGSAGHTTLGITLMI 217
Query: 287 NGVLCATPLIFIIPSACYLKLSEEPRTHSDK 317
GV C LI + A YL E H ++
Sbjct: 218 GGVTCILSLICALALA-YLDQRAERILHKEQ 247
>gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9,
39kDa [Homo sapiens]
Length = 377
Score = 31.2 bits (69), Expect = 1.6
Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 18/108 (16%)
Query: 45 KTFGFPG---YLLLSVLQFLYPFIVDPENVFIGRHFIIGLSTVTFTLPLSLYRNIAKLGK 101
K+F F G YLL ++++ +F H + + F LPL YR +A++ +
Sbjct: 261 KSFAFVGPSRYLLFHLVKY----------IFAVAHRLF----LPFPLPLFAYRWVARVFE 306
Query: 102 VSLISTGLTTLILGIVMARAISLGPHIPKTEDAWVFAKPNAIQAVGVM 149
+S +T + + + L PH+P ED + A P ++A+ V+
Sbjct: 307 ISPFEPWITRDKVERMHITDMKL-PHLPGLEDLGIQATPLELKAIEVL 353
>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
Length = 622
Score = 30.0 bits (66), Expect = 3.7
Identities = 12/20 (60%), Positives = 14/20 (70%)
Query: 207 DLFENYCRNDDLVTFGRFCY 226
DL EN+CRN D T G +CY
Sbjct: 151 DLQENFCRNPDSSTTGPWCY 170
>gi|205277383 macrophage stimulating 1 (hepatocyte growth
factor-like) [Homo sapiens]
Length = 725
Score = 30.0 bits (66), Expect = 3.7
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 199 TFTGFTQGDLFENYCRNDDLVTFGRFCY 226
TFT L EN+CRN D + G +CY
Sbjct: 419 TFTSEPHAQLEENFCRNPDGDSHGPWCY 446
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.143 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,114,980
Number of Sequences: 37866
Number of extensions: 529838
Number of successful extensions: 1469
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1414
Number of HSP's gapped (non-prelim): 34
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.