Guide to the Human Genome
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Search of human proteins with 27734885

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27734885 hypothetical protein LOC219621 [Homo sapiens]
         (208 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27734885 hypothetical protein LOC219621 [Homo sapiens]             412   e-116
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap...    36   0.020
gi|91176323 hypothetical protein LOC203076 [Homo sapiens]              36   0.020
gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled...    32   0.29 
gi|62510076 hypothetical protein LOC90835 [Homo sapiens]               31   0.65 
gi|17136078 VGF nerve growth factor inducible precursor [Homo sa...    30   1.5  
gi|197245373 proline rich 22 isoform 1 [Homo sapiens]                  29   2.5  
gi|23503299 proline rich 22 isoform 2 [Homo sapiens]                   29   2.5  
gi|4758648 kinesin family member 5B [Homo sapiens]                     29   3.2  
gi|21361116 versican isoform 1 [Homo sapiens]                          28   4.2  
gi|52627149 telomeric repeat binding factor 2, interacting prote...    28   4.2  
gi|4758650 kinesin family member 5C [Homo sapiens]                     28   5.5  
gi|118498362 kinectin 1 isoform b [Homo sapiens]                       28   7.2  
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       28   7.2  
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       28   7.2  
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        28   7.2  
gi|96974985 coiled-coil and C2 domain containing 1A [Homo sapiens]     28   7.2  
gi|4826742 glutamine-fructose-6-phosphate transaminase 2 [Homo s...    28   7.2  
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]                28   7.2  
gi|153082752 interferon regulatory factor 2 [Homo sapiens]             27   9.4  
gi|22027482 neuronal PAS domain protein 1 [Homo sapiens]               27   9.4  
gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]          27   9.4  
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]            27   9.4  
gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]           27   9.4  

>gi|27734885 hypothetical protein LOC219621 [Homo sapiens]
          Length = 208

 Score =  412 bits (1060), Expect = e-116
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 1   MDFSIIQYSKFMTLLAMSLQNLKTLHMSLEESIKWLGEVMAEIGPTHSQKSEDWNIFDVK 60
           MDFSIIQYSKFMTLLAMSLQNLKTLHMSLEESIKWLGEVMAEIGPTHSQKSEDWNIFDVK
Sbjct: 1   MDFSIIQYSKFMTLLAMSLQNLKTLHMSLEESIKWLGEVMAEIGPTHSQKSEDWNIFDVK 60

Query: 61  QANAIIDYLKISLFQHYKLYEFMFYSAREEIVIGTEQVIEVVKSACGPFPNPLEEGISFD 120
           QANAIIDYLKISLFQHYKLYEFMFYSAREEIVIGTEQVIEVVKSACGPFPNPLEEGISFD
Sbjct: 61  QANAIIDYLKISLFQHYKLYEFMFYSAREEIVIGTEQVIEVVKSACGPFPNPLEEGISFD 120

Query: 121 IYSTFIEPPTILDTEMKRLDQEQGPEESQPETDTSDMDPLVGFTIEDVKSVLDQVTDDIL 180
           IYSTFIEPPTILDTEMKRLDQEQGPEESQPETDTSDMDPLVGFTIEDVKSVLDQVTDDIL
Sbjct: 121 IYSTFIEPPTILDTEMKRLDQEQGPEESQPETDTSDMDPLVGFTIEDVKSVLDQVTDDIL 180

Query: 181 IGIQTEINEKLQIQEEAFNARIEKLKKA 208
           IGIQTEINEKLQIQEEAFNARIEKLKKA
Sbjct: 181 IGIQTEINEKLQIQEEAFNARIEKLKKA 208


>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sapiens]
          Length = 1555

 Score = 36.2 bits (82), Expect = 0.020
 Identities = 15/51 (29%), Positives = 28/51 (54%)

Query: 134  TEMKRLDQEQGPEESQPETDTSDMDPLVGFTIEDVKSVLDQVTDDILIGIQ 184
            T++  +  +  PEE + + +  D+  L  FT+E++K   D V + +  GIQ
Sbjct: 1292 TQVSEVTAQPPPEEEEDQNEDQDVPDLTNFTVEELKQRYDSVINRLYTGIQ 1342


>gi|91176323 hypothetical protein LOC203076 [Homo sapiens]
          Length = 294

 Score = 36.2 bits (82), Expect = 0.020
 Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 14/89 (15%)

Query: 57  FDVKQANAIIDYLKISLFQHYKLYEFMFYSAREEIVIGTEQVIEV----VKSACGPFPNP 112
           F+     A+ DY   +  +HYKLY++         V+G +Q +++    ++    P P P
Sbjct: 102 FNTTHLLALCDYFHHTFIRHYKLYQY---------VLGQDQQVDLTVAHLEVCMPPHPLP 152

Query: 113 LEEGISFDIYSTFIEPPTILDTE-MKRLD 140
           L EG+  D++    +  T+ + E  KR D
Sbjct: 153 LAEGMDRDLWIHEQQVATLTEAEAQKRAD 181


>gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled-coil
            containing 2 [Homo sapiens]
          Length = 1990

 Score = 32.3 bits (72), Expect = 0.29
 Identities = 16/48 (33%), Positives = 31/48 (64%), Gaps = 7/48 (14%)

Query: 141  QEQGPEESQPETDTSDMDPLVGFTIEDV--KSVLDQVTDDILIGIQTE 186
            Q+Q PEE++PE    D+     ++++D+  +  L+Q  +++ IG+QTE
Sbjct: 1388 QQQLPEEAEPEPQHEDI-----YSVQDIFEEEYLEQDVENVSIGLQTE 1430


>gi|62510076 hypothetical protein LOC90835 [Homo sapiens]
          Length = 294

 Score = 31.2 bits (69), Expect = 0.65
 Identities = 33/154 (21%), Positives = 69/154 (44%), Gaps = 24/154 (15%)

Query: 55  NIFDVKQANAIIDYLKISLFQHYKLYEFMFYSAREEIVIGTEQV-IEVVKSACGPFPNPL 113
           ++F  +Q  A+ DY+  + F+H+KLY+++F          T QV +++  +  G  P  L
Sbjct: 150 DLFKEEQLLALEDYVVNTYFRHFKLYKYVF----------TPQVRLDLSLTYMGLQPPKL 199

Query: 114 EEGISFDIYSTFIEPPTILDTEMKRLDQEQGPEESQPETDTSDMDPLVGFTIEDVKSVLD 173
                +    T  E    ++ +     +E+    + PE + S +  L  +    V   L+
Sbjct: 200 -----WPESETEEEESKEMEEQAVTPQKEELETVAPPEPEPSHIHVLRAYIKTQVNKELE 254

Query: 174 QVTDDILIGIQTEINEKLQIQEEAFNARIEKLKK 207
           Q        +Q  + E+L+  EE  ++++  L++
Sbjct: 255 Q--------LQGLVEERLKASEERLSSKLTALER 280


>gi|17136078 VGF nerve growth factor inducible precursor [Homo
           sapiens]
          Length = 615

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 1/65 (1%)

Query: 133 DTEMKRLDQEQGPEESQPETDTSDMDPLVGFTIEDVKSVLDQVTDDILIGIQTEINEKLQ 192
           +T   R  + +G EE   E D  +MDP    ++ ++ + L    DD+ + I  E+ EK +
Sbjct: 423 ETPGHRRKEAEGTEEGGEEEDDEEMDPQTIDSLIELSTKLHLPADDV-VSIIEEVEEKRK 481

Query: 193 IQEEA 197
            ++ A
Sbjct: 482 RKKNA 486


>gi|197245373 proline rich 22 isoform 1 [Homo sapiens]
          Length = 422

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 24/61 (39%), Positives = 29/61 (47%), Gaps = 18/61 (29%)

Query: 102 VKSACGPFPNPLEEGISFDIYSTFIEPPTILDT--------EMKRLDQEQGPEESQPETD 153
           ++S C P     EE +SFD YS     P ILDT          K LD+EQ P    P T+
Sbjct: 326 IRSLCLP-----EELLSFD-YSV----PEILDTVSNVDYFFNFKALDEEQPPHPGPPATN 375

Query: 154 T 154
           T
Sbjct: 376 T 376


>gi|23503299 proline rich 22 isoform 2 [Homo sapiens]
          Length = 420

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 24/61 (39%), Positives = 29/61 (47%), Gaps = 18/61 (29%)

Query: 102 VKSACGPFPNPLEEGISFDIYSTFIEPPTILDT--------EMKRLDQEQGPEESQPETD 153
           ++S C P     EE +SFD YS     P ILDT          K LD+EQ P    P T+
Sbjct: 324 IRSLCLP-----EELLSFD-YSV----PEILDTVSNVDYFFNFKALDEEQPPHPGPPATN 373

Query: 154 T 154
           T
Sbjct: 374 T 374


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 5/90 (5%)

Query: 5   IIQYSKFMTLLAMSLQNLKTLHMSLEESIKWLGEVMAEI---GPTHSQKSEDWNIFDVKQ 61
           I Q+   +  L   LQN++     LEES+  L E + ++      H  + E  N   V+ 
Sbjct: 636 ISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLN--KVQT 693

Query: 62  ANAIIDYLKISLFQHYKLYEFMFYSAREEI 91
           AN +   ++  +  H + ++    S R+E+
Sbjct: 694 ANEVKQAVEQQIQSHRETHQKQISSLRDEV 723


>gi|21361116 versican isoform 1 [Homo sapiens]
          Length = 3396

 Score = 28.5 bits (62), Expect = 4.2
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 13/110 (11%)

Query: 81   EFMFYSAREEIVIGTEQVIEVVK--SACGPFPNPLE-EGISFDIYSTFIEPPTILDTEMK 137
            E   Y+  E   +G  + +++ K  S    F +  E EG++F  YS+  EP T +D+   
Sbjct: 913  EGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDS--- 969

Query: 138  RLDQEQGPEESQPETDTSDMDPLVGFTIEDVKSVLDQVTDDILIGIQTEI 187
                   P    P+TD   + P    ++     VL + + DIL+  QT +
Sbjct: 970  ---SHTIPLSVIPKTDWGVLVP----SVPSEDEVLGEPSQDILVIDQTRL 1012


>gi|52627149 telomeric repeat binding factor 2, interacting protein
           [Homo sapiens]
          Length = 399

 Score = 28.5 bits (62), Expect = 4.2
 Identities = 24/96 (25%), Positives = 44/96 (45%), Gaps = 10/96 (10%)

Query: 88  REEIVIGTEQVIEVVKSACGPFPNPL--EEGISFDIYSTFIE--PPTILDTEMKRLDQEQ 143
           +EEI    E V +++  A   F   +  E    F+I+ T  +  PPT  +      D E 
Sbjct: 240 KEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEE------DSET 293

Query: 144 GPEESQPETDTSDMDPLVGFTIEDVKSVLDQVTDDI 179
            P+E + E +     P VG  I+ ++ ++++   D+
Sbjct: 294 QPDEEEEEEEEKVSQPEVGAAIKIIRQLMEKFNLDL 329


>gi|4758650 kinesin family member 5C [Homo sapiens]
          Length = 957

 Score = 28.1 bits (61), Expect = 5.5
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 12/72 (16%)

Query: 135 EMKRLDQEQGPEESQPETDTSDMDPLVGFTIEDVKSVLDQVTDDILIGIQTEINEKLQIQ 194
           EMK+  ++Q   ES  E     +  L    IE+ + ++D++ D         +N+KLQ++
Sbjct: 698 EMKKALEQQ--MESHREAHQKQLSRLRD-EIEEKQKIIDEIRD---------LNQKLQLE 745

Query: 195 EEAFNARIEKLK 206
           +E  ++   KLK
Sbjct: 746 QEKLSSDYNKLK 757


>gi|118498362 kinectin 1 isoform b [Homo sapiens]
          Length = 1306

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 5/54 (9%)

Query: 150 PETDTSDMDPLVGFTIEDVKSVLDQVTDDILIGIQTEINEKLQIQEEAFNARIE 203
           P  D +D  P+V     D + V+D +  D + GIQ    +KL+ + +  NA ++
Sbjct: 235 PLMDNADSSPVV-----DKREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVK 283


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 5/54 (9%)

Query: 150 PETDTSDMDPLVGFTIEDVKSVLDQVTDDILIGIQTEINEKLQIQEEAFNARIE 203
           P  D +D  P+V     D + V+D +  D + GIQ    +KL+ + +  NA ++
Sbjct: 235 PLMDNADSSPVV-----DKREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVK 283


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 5/54 (9%)

Query: 150 PETDTSDMDPLVGFTIEDVKSVLDQVTDDILIGIQTEINEKLQIQEEAFNARIE 203
           P  D +D  P+V     D + V+D +  D + GIQ    +KL+ + +  NA ++
Sbjct: 235 PLMDNADSSPVV-----DKREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVK 283


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 5/54 (9%)

Query: 150 PETDTSDMDPLVGFTIEDVKSVLDQVTDDILIGIQTEINEKLQIQEEAFNARIE 203
           P  D +D  P+V     D + V+D +  D + GIQ    +KL+ + +  NA ++
Sbjct: 235 PLMDNADSSPVV-----DKREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVK 283


>gi|96974985 coiled-coil and C2 domain containing 1A [Homo sapiens]
          Length = 951

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 10/30 (33%), Positives = 18/30 (60%)

Query: 131 ILDTEMKRLDQEQGPEESQPETDTSDMDPL 160
           +L+T MK  +Q++GPE+ + E       P+
Sbjct: 428 VLETAMKLANQDEGPEDEEDEVPKKQNSPV 457


>gi|4826742 glutamine-fructose-6-phosphate transaminase 2 [Homo
           sapiens]
          Length = 682

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 13/94 (13%)

Query: 34  KWLGEVMAEIGPTHSQKSEDWNIFDVKQANAIIDYLKISLFQHYKLYEFMFYSAREEIVI 93
           +W    +     +H Q+S+  N F V     I +Y  +  F   K YEF       E   
Sbjct: 92  RWATHGVPSAVNSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEF-------ESET 144

Query: 94  GTEQVIEVVKSACGPFPNPLEEGISFDIYSTFIE 127
            TE + +++K     F N   E I+F   ST +E
Sbjct: 145 DTETIAKLIKYV---FDNRETEDITF---STLVE 172


>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
          Length = 804

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 13/59 (22%)

Query: 104 SACGPFPNPLEEGISFDIYSTFIEP-------------PTILDTEMKRLDQEQGPEESQ 149
           SAC P  +P   G+S D+ S  I P             P+I  T   +LD    P  ++
Sbjct: 415 SACAPISSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANR 473


>gi|153082752 interferon regulatory factor 2 [Homo sapiens]
          Length = 349

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 16/73 (21%), Positives = 33/73 (45%), Gaps = 1/73 (1%)

Query: 127 EPPTILDTEMKRLDQEQGPEESQPETDTSDMDPLVGFTIEDVKSVLDQVTDDILIGIQTE 186
           +P T  + ++K + QE            SD+ P        +K+ +D   + I++G Q+ 
Sbjct: 124 KPKTEKEDKVKHIKQEPVESSLGLSNGVSDLSPEYAVLTSTIKNEVDSTVNIIVVG-QSH 182

Query: 187 INEKLQIQEEAFN 199
           ++  ++ QE   N
Sbjct: 183 LDSNIENQEIVTN 195


>gi|22027482 neuronal PAS domain protein 1 [Homo sapiens]
          Length = 590

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 22/68 (32%)

Query: 103 KSACGPFPNPLEEGISFDIYSTFIEPPT-----------ILDTEMKRLDQEQGPEESQPE 151
           + A  P P P E            EPPT              T+ KR+  E GP E++  
Sbjct: 427 EEASSPGPEPTEP-----------EPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGS 475

Query: 152 TDTSDMDP 159
            D+ D DP
Sbjct: 476 EDSGDEDP 483


>gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]
          Length = 494

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 5/89 (5%)

Query: 73  LFQHYKLYEFMFYSAREEIVIGTEQVI---EVVKSACGPFPN--PLEEGISFDIYSTFIE 127
           L QH K   F  +   +++  G    I   +V K      PN  P    I  +IY     
Sbjct: 26  LIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGI 85

Query: 128 PPTILDTEMKRLDQEQGPEESQPETDTSD 156
           P   +D   + L+Q+    + + + D SD
Sbjct: 86  PEKDMDERRRLLEQKTQESQKKKQQDDSD 114


>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
          Length = 478

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 5/89 (5%)

Query: 73  LFQHYKLYEFMFYSAREEIVIGTEQVI---EVVKSACGPFPN--PLEEGISFDIYSTFIE 127
           L QH K   F  +   +++  G    I   +V K      PN  P    I  +IY     
Sbjct: 26  LIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGI 85

Query: 128 PPTILDTEMKRLDQEQGPEESQPETDTSD 156
           P   +D   + L+Q+    + + + D SD
Sbjct: 86  PEKDMDERRRLLEQKTQESQKKKQQDDSD 114


>gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]
          Length = 463

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 5/89 (5%)

Query: 73  LFQHYKLYEFMFYSAREEIVIGTEQVI---EVVKSACGPFPN--PLEEGISFDIYSTFIE 127
           L QH K   F  +   +++  G    I   +V K      PN  P    I  +IY     
Sbjct: 26  LIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGI 85

Query: 128 PPTILDTEMKRLDQEQGPEESQPETDTSD 156
           P   +D   + L+Q+    + + + D SD
Sbjct: 86  PEKDMDERRRLLEQKTQESQKKKQQDDSD 114


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,450,411
Number of Sequences: 37866
Number of extensions: 325199
Number of successful extensions: 1069
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1061
Number of HSP's gapped (non-prelim): 27
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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