Guide to the Human Genome
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Search of human proteins with 27502391

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27502391 nuclear factor of activated T-cells, cytosolic
component 1 isoform E [Homo sapiens]
         (812 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27502386 nuclear factor of activated T-cells, cytosolic compo...  1682   0.0  
gi|27502391 nuclear factor of activated T-cells, cytosolic compo...  1682   0.0  
gi|19923350 nuclear factor of activated T-cells, cytosolic compo...  1625   0.0  
gi|27502393 nuclear factor of activated T-cells, cytosolic compo...  1352   0.0  
gi|27502388 nuclear factor of activated T-cells, cytosolic compo...   726   0.0  
gi|27886539 nuclear factor of activated T-cells, cytoplasmic, ca...   585   e-167
gi|27886541 nuclear factor of activated T-cells, cytoplasmic, ca...   585   e-167
gi|209862843 nuclear factor of activated T-cells, cytoplasmic, c...   579   e-165
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca...   559   e-159
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca...   559   e-159
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca...   559   e-159
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal...   559   e-159
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...   429   e-120
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...   429   e-120
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom...   218   1e-56
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo...   218   1e-56
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho...   218   1e-56
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho...   218   1e-56
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom...   218   1e-56
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ...    61   4e-09
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ...    60   6e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   5e-06
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               51   5e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    49   2e-05
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              47   5e-05
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                47   9e-05
gi|157168329 formin 1 [Homo sapiens]                                   46   1e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   2e-04
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            45   3e-04
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    45   3e-04

>gi|27502386 nuclear factor of activated T-cells, cytosolic
           component 1 isoform C [Homo sapiens]
          Length = 930

 Score = 1682 bits (4355), Expect = 0.0
 Identities = 812/812 (100%), Positives = 812/812 (100%)

Query: 1   MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ 60
           MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ
Sbjct: 1   MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ 60

Query: 61  TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN 120
           TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN
Sbjct: 61  TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN 120

Query: 121 QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY 180
           QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY
Sbjct: 121 QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY 180

Query: 181 SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG 240
           SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG
Sbjct: 181 SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG 240

Query: 241 ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV 300
           ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV
Sbjct: 241 ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV 300

Query: 301 AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 360
           AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS
Sbjct: 301 AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 360

Query: 361 FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ 420
           FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ
Sbjct: 361 FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ 420

Query: 421 PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ 480
           PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ
Sbjct: 421 PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ 480

Query: 481 VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI 540
           VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI
Sbjct: 481 VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI 540

Query: 541 GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK 600
           GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK
Sbjct: 541 GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK 600

Query: 601 MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH 660
           MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH
Sbjct: 601 MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH 660

Query: 661 VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ 720
           VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ
Sbjct: 661 VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ 720

Query: 721 LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP 780
           LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP
Sbjct: 721 LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP 780

Query: 781 AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 812
           AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ
Sbjct: 781 AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 812


>gi|27502391 nuclear factor of activated T-cells, cytosolic
           component 1 isoform E [Homo sapiens]
          Length = 812

 Score = 1682 bits (4355), Expect = 0.0
 Identities = 812/812 (100%), Positives = 812/812 (100%)

Query: 1   MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ 60
           MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ
Sbjct: 1   MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ 60

Query: 61  TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN 120
           TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN
Sbjct: 61  TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN 120

Query: 121 QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY 180
           QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY
Sbjct: 121 QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY 180

Query: 181 SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG 240
           SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG
Sbjct: 181 SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG 240

Query: 241 ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV 300
           ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV
Sbjct: 241 ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV 300

Query: 301 AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 360
           AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS
Sbjct: 301 AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 360

Query: 361 FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ 420
           FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ
Sbjct: 361 FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ 420

Query: 421 PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ 480
           PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ
Sbjct: 421 PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ 480

Query: 481 VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI 540
           VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI
Sbjct: 481 VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI 540

Query: 541 GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK 600
           GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK
Sbjct: 541 GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK 600

Query: 601 MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH 660
           MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH
Sbjct: 601 MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH 660

Query: 661 VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ 720
           VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ
Sbjct: 661 VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ 720

Query: 721 LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP 780
           LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP
Sbjct: 721 LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP 780

Query: 781 AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 812
           AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ
Sbjct: 781 AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 812


>gi|19923350 nuclear factor of activated T-cells, cytosolic
           component 1 isoform B [Homo sapiens]
          Length = 825

 Score = 1625 bits (4207), Expect = 0.0
 Identities = 784/787 (99%), Positives = 785/787 (99%)

Query: 26  AAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 85
           +A  EHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA
Sbjct: 39  SAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 98

Query: 86  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 145
           GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS
Sbjct: 99  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 158

Query: 146 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 205
           LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE
Sbjct: 159 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 218

Query: 206 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 265
           EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS
Sbjct: 219 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 278

Query: 266 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 325
           PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT
Sbjct: 279 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 338

Query: 326 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 385
           TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK
Sbjct: 339 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 398

Query: 386 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 445
           PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH
Sbjct: 399 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 458

Query: 446 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 505
           PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE
Sbjct: 459 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 518

Query: 506 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 565
           IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL
Sbjct: 519 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 578

Query: 566 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 625
           QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH
Sbjct: 579 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 638

Query: 626 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV 685
           VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV
Sbjct: 639 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV 698

Query: 686 PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM 745
           PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM
Sbjct: 699 PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM 758

Query: 746 PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP 805
           PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP
Sbjct: 759 PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP 818

Query: 806 PALLPQQ 812
           PALLPQQ
Sbjct: 819 PALLPQQ 825


>gi|27502393 nuclear factor of activated T-cells, cytosolic
           component 1 isoform A [Homo sapiens]
          Length = 716

 Score = 1352 bits (3499), Expect = 0.0
 Identities = 656/659 (99%), Positives = 657/659 (99%)

Query: 26  AAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 85
           +A  EHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA
Sbjct: 39  SAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 98

Query: 86  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 145
           GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS
Sbjct: 99  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 158

Query: 146 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 205
           LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE
Sbjct: 159 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 218

Query: 206 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 265
           EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS
Sbjct: 219 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 278

Query: 266 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 325
           PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT
Sbjct: 279 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 338

Query: 326 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 385
           TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK
Sbjct: 339 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 398

Query: 386 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 445
           PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH
Sbjct: 399 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 458

Query: 446 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 505
           PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE
Sbjct: 459 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 518

Query: 506 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 565
           IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL
Sbjct: 519 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 578

Query: 566 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 625
           QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH
Sbjct: 579 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 638

Query: 626 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 684
           VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN
Sbjct: 639 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 697


>gi|27502388 nuclear factor of activated T-cells, cytosolic
           component 1 isoform D [Homo sapiens]
          Length = 353

 Score =  726 bits (1874), Expect = 0.0
 Identities = 353/353 (100%), Positives = 353/353 (100%)

Query: 460 MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID 519
           MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID
Sbjct: 1   MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID 60

Query: 520 CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA 579
           CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA
Sbjct: 61  CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA 120

Query: 580 QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK 639
           QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK
Sbjct: 121 QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK 180

Query: 640 PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPA 699
           PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPA
Sbjct: 181 PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPA 240

Query: 700 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS 759
           PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS
Sbjct: 241 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS 300

Query: 760 PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 812
           PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ
Sbjct: 301 PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 353


>gi|27886539 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 2 isoform B [Homo sapiens]
          Length = 921

 Score =  585 bits (1507), Expect = e-167
 Identities = 382/840 (45%), Positives = 474/840 (56%), Gaps = 93/840 (11%)

Query: 3   GLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTS 62
           G    E DF  LF++   +       P  +  AS    PA P            + L+  
Sbjct: 22  GSPQDELDFSILFDYEYLNPNEEE--PNAHKVASPPSGPAYPDDVLD-------YGLKPY 72

Query: 63  TPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQF 122
           +P      + P  +G     GP   FLS+   +P GA  L SPRIEIT      H   Q 
Sbjct: 73  SPLASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQA 124

Query: 123 FHDVEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS 175
              + + D     ++ P          TL +P  E YR+P CLSPASS SS S       
Sbjct: 125 VGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS------- 177

Query: 176 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE 235
                   + S   SP+ SPCVSP    P++  P+         SPR SP  SPR S+ E
Sbjct: 178 --------FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAE 228

Query: 236 ESWLGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD 285
           +S LG  S      SR +SP  KR++S    L    P  SP  S +PSP  S  V+  D 
Sbjct: 229 DSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDH 288

Query: 286 -SWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDL 344
            S  G      S+ I+ A+N+L TDS      G+P K  KT+ +  P            +
Sbjct: 289 GSPAGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------V 332

Query: 345 GSPPPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----T 392
            + P  A      Y + + +       R+    +  L VP     W  PKPL P     +
Sbjct: 333 SAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICS 387

Query: 393 SYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHG 452
             ++ +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA  GGHP+VQLHG
Sbjct: 388 IPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHG 447

Query: 453 YLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPEN 512
           Y+EN+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N
Sbjct: 448 YMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKN 507

Query: 513 SMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPI 572
           +MRA IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPI
Sbjct: 508 NMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPI 567

Query: 573 ECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK 632
           ECSQRSA ELP+VE+Q TDS  V GG++M+L+G NF  +SKV+F EK  DG  +WEMEA 
Sbjct: 568 ECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEAT 627

Query: 633 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEP 692
            D+D  +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P  VP IKTEP
Sbjct: 628 VDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEP 685

Query: 693 TDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVS 752
           TD+Y+P   C P   GL    +PYY Q   +   P SCLVA   PC Q  T + ++P   
Sbjct: 686 TDEYDPTLICSPTHGGLG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDAR 741

Query: 753 PKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 810
            +  + +   Y +   S     LG  QPA  A   ++ D  R V  H GS GQ    L P
Sbjct: 742 YQQQNPAAVLYQRS-KSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 800


>gi|27886541 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 2 isoform C [Homo sapiens]
          Length = 925

 Score =  585 bits (1507), Expect = e-167
 Identities = 382/840 (45%), Positives = 474/840 (56%), Gaps = 93/840 (11%)

Query: 3   GLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTS 62
           G    E DF  LF++   +       P  +  AS    PA P            + L+  
Sbjct: 22  GSPQDELDFSILFDYEYLNPNEEE--PNAHKVASPPSGPAYPDDVLD-------YGLKPY 72

Query: 63  TPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQF 122
           +P      + P  +G     GP   FLS+   +P GA  L SPRIEIT      H   Q 
Sbjct: 73  SPLASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQA 124

Query: 123 FHDVEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS 175
              + + D     ++ P          TL +P  E YR+P CLSPASS SS S       
Sbjct: 125 VGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS------- 177

Query: 176 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE 235
                   + S   SP+ SPCVSP    P++  P+         SPR SP  SPR S+ E
Sbjct: 178 --------FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAE 228

Query: 236 ESWLGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD 285
           +S LG  S      SR +SP  KR++S    L    P  SP  S +PSP  S  V+  D 
Sbjct: 229 DSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDH 288

Query: 286 -SWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDL 344
            S  G      S+ I+ A+N+L TDS      G+P K  KT+ +  P            +
Sbjct: 289 GSPAGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------V 332

Query: 345 GSPPPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----T 392
            + P  A      Y + + +       R+    +  L VP     W  PKPL P     +
Sbjct: 333 SAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICS 387

Query: 393 SYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHG 452
             ++ +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA  GGHP+VQLHG
Sbjct: 388 IPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHG 447

Query: 453 YLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPEN 512
           Y+EN+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N
Sbjct: 448 YMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKN 507

Query: 513 SMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPI 572
           +MRA IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPI
Sbjct: 508 NMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPI 567

Query: 573 ECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK 632
           ECSQRSA ELP+VE+Q TDS  V GG++M+L+G NF  +SKV+F EK  DG  +WEMEA 
Sbjct: 568 ECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEAT 627

Query: 633 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEP 692
            D+D  +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P  VP IKTEP
Sbjct: 628 VDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEP 685

Query: 693 TDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVS 752
           TD+Y+P   C P   GL    +PYY Q   +   P SCLVA   PC Q  T + ++P   
Sbjct: 686 TDEYDPTLICSPTHGGLG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDAR 741

Query: 753 PKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 810
            +  + +   Y +   S     LG  QPA  A   ++ D  R V  H GS GQ    L P
Sbjct: 742 YQQQNPAAVLYQRS-KSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 800


>gi|209862843 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 2 isoform D [Homo sapiens]
          Length = 901

 Score =  579 bits (1493), Expect = e-165
 Identities = 374/807 (46%), Positives = 462/807 (57%), Gaps = 94/807 (11%)

Query: 46  PTAHSTLPAPC----------HNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTR 95
           P AH     P           + L+  +P      + P  +G     GP   FLS+   +
Sbjct: 26  PNAHKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQK-FLSAA--K 82

Query: 96  PDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTA-------TLSLPS 148
           P GA  L SPRIEIT      H   Q    + + D     ++ P          TL +P 
Sbjct: 83  PAGASGL-SPRIEITPS----HELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPG 137

Query: 149 LEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGF 208
            E YR+P CLSPASS SS S               + S   SP+ SPCVSP    P++  
Sbjct: 138 FEGYREPLCLSPASSGSSAS---------------FISDTFSPYTSPCVSPNNGGPDDLC 182

Query: 209 PRGLGACTLLGSPRHSPSTSPRASVTEESWLGARS------SRPASPCNKRKYS----LN 258
           P+         SPR SP  SPR S+ E+S LG  S      SR +SP  KR++S    L 
Sbjct: 183 PQFQNIPAHY-SPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALV 241

Query: 259 GRQPPYSPHHSPTPSPHGSPRVSVTDD-SWLGNTTQYTSSAIVAAINALTTDSSLDLGDG 317
              P  SP  S +PSP  S  V+  D  S  G      S+ I+ A+N+L TDS      G
Sbjct: 242 ALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPC----G 297

Query: 318 VPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHI-------RKGGFC 370
           +P K  KT+ +  P            + + P  A      Y + + +       R+    
Sbjct: 298 IPPKMWKTSPDPSP------------VSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAP 345

Query: 371 DQYLAVPQHPYQWAKPKPLSP-----TSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHH 425
           +  L VP     W  PKPL P     +  ++ +LP L+W L S SG YELRIEVQPK HH
Sbjct: 346 ESILLVPP---TW--PKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHH 400

Query: 426 RAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRIT 485
           RAHYETEGSRGAVKA  GGHP+VQLHGY+EN+PL LQ+FIGTAD+R+L+PHAFYQVHRIT
Sbjct: 401 RAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRIT 460

Query: 486 GKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNT 545
           GKTV+TTS+E I+ NTKVLEIPL P+N+MRA IDCAGILKLRN+DIELRKGETDIGRKNT
Sbjct: 461 GKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNT 520

Query: 546 RVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSG 605
           RVRLVFRVH+P+ SGR +SLQ ASNPIECSQRSA ELP+VE+Q TDS  V GG++M+L+G
Sbjct: 521 RVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTG 580

Query: 606 HNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYV 665
            NF  +SKV+F EK  DG  +WEMEA  D+D  +PN L VEIP +RN+ I +PV V+FYV
Sbjct: 581 QNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYV 640

Query: 666 CNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPP 725
            NGKRKRSQ Q FTY P  VP IKTEPTD+Y+P   C P   GL    +PYY Q   +  
Sbjct: 641 INGKRKRSQPQHFTYHP--VPAIKTEPTDEYDPTLICSPTHGGLG--SQPYYPQHPMVAE 696

Query: 726 DPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAP 785
            P SCLVA   PC Q  T + ++P    +  + +   Y +   S     LG  QPA  A 
Sbjct: 697 SP-SCLVATMAPCQQFRTGL-SSPDARYQQQNPAAVLYQRS-KSLSPSLLGYQQPALMAA 753

Query: 786 --AVQDVPRPVATHPGSPGQPPPALLP 810
             ++ D  R V  H GS GQ    L P
Sbjct: 754 PLSLADAHRSVLVHAGSQGQSSALLHP 780


>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 1 [Homo sapiens]
          Length = 1075

 Score =  559 bits (1440), Expect = e-159
 Identities = 332/663 (50%), Positives = 420/663 (63%), Gaps = 59/663 (8%)

Query: 98  GAPALESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPS 156
           G    E P I+ITS     H   +    D+++ D        PS   L LP   +YR+ S
Sbjct: 102 GPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESS 161

Query: 157 CL-SPASSLSSRSCNSEASSYESNYSYPY----------------ASPQTSPWQSP--CV 197
              SPASS+SSRS  S+ASS ES  S+ Y                 SP TSP  SP  C 
Sbjct: 162 LSPSPASSISSRSWFSDASSCES-LSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220

Query: 198 SPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNK 252
             +T   + G    L       SPR SP  SPR+SVT+E+WL  R     SSRP SPC K
Sbjct: 221 GEETWHQQYGLGHSL-------SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGK 273

Query: 253 RKYSLNGRQPPY----SPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTT 308
           R++S    +  Y    SPHHSP PSP  SPR SVT+D+WL N + +  S +  A+     
Sbjct: 274 RRHS--SAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQY 330

Query: 309 DSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGG 368
               D    +P+K+RKT+ +Q   +  K+E   +D GS  P  + + +D    Q+  K  
Sbjct: 331 CVETD----IPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKD 386

Query: 369 FC-DQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRA 427
            C DQ+L+VP  P+ W+KPKP     + + +LP LDW LP+H G  EL+IEVQPK+HHRA
Sbjct: 387 SCGDQFLSVPS-PFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRA 445

Query: 428 HYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGK 487
           HYETEGSRGAVKAS GGHP+V+L GY E +P+ LQ+FIGTADDR LRPHAFYQVHRITGK
Sbjct: 446 HYETEGSRGAVKASTGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGK 504

Query: 488 TVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRV 547
           TV+T S E I+++TKVLEIPLLPEN+M A IDCAGILKLRNSDIELRKGETDIGRKNTRV
Sbjct: 505 TVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRV 564

Query: 548 RLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHN 607
           RLVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQELP +EK S +S  V GG +MV++G N
Sbjct: 565 RLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSN 624

Query: 608 FLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN 667
           FL +SK+IF+EK  DG   WE+E K  R+ C+   +V+E+PP+ N  +T+ V V FY+CN
Sbjct: 625 FLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN 684

Query: 668 GKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP 727
           GKRK+SQ QRFTY P    ++K E  ++ + +      S    P+P P  +Q+   P   
Sbjct: 685 GKRKKSQSQRFTYTPV---LMKQEHREEIDLS------SVPSLPVPHPAQTQR---PSSD 732

Query: 728 SSC 730
           S C
Sbjct: 733 SGC 735


>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 4 [Homo sapiens]
          Length = 1045

 Score =  559 bits (1440), Expect = e-159
 Identities = 332/663 (50%), Positives = 420/663 (63%), Gaps = 59/663 (8%)

Query: 98  GAPALESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPS 156
           G    E P I+ITS     H   +    D+++ D        PS   L LP   +YR+ S
Sbjct: 102 GPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESS 161

Query: 157 CL-SPASSLSSRSCNSEASSYESNYSYPY----------------ASPQTSPWQSP--CV 197
              SPASS+SSRS  S+ASS ES  S+ Y                 SP TSP  SP  C 
Sbjct: 162 LSPSPASSISSRSWFSDASSCES-LSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220

Query: 198 SPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNK 252
             +T   + G    L       SPR SP  SPR+SVT+E+WL  R     SSRP SPC K
Sbjct: 221 GEETWHQQYGLGHSL-------SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGK 273

Query: 253 RKYSLNGRQPPY----SPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTT 308
           R++S    +  Y    SPHHSP PSP  SPR SVT+D+WL N + +  S +  A+     
Sbjct: 274 RRHS--SAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQY 330

Query: 309 DSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGG 368
               D    +P+K+RKT+ +Q   +  K+E   +D GS  P  + + +D    Q+  K  
Sbjct: 331 CVETD----IPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKD 386

Query: 369 FC-DQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRA 427
            C DQ+L+VP  P+ W+KPKP     + + +LP LDW LP+H G  EL+IEVQPK+HHRA
Sbjct: 387 SCGDQFLSVPS-PFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRA 445

Query: 428 HYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGK 487
           HYETEGSRGAVKAS GGHP+V+L GY E +P+ LQ+FIGTADDR LRPHAFYQVHRITGK
Sbjct: 446 HYETEGSRGAVKASTGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGK 504

Query: 488 TVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRV 547
           TV+T S E I+++TKVLEIPLLPEN+M A IDCAGILKLRNSDIELRKGETDIGRKNTRV
Sbjct: 505 TVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRV 564

Query: 548 RLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHN 607
           RLVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQELP +EK S +S  V GG +MV++G N
Sbjct: 565 RLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSN 624

Query: 608 FLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN 667
           FL +SK+IF+EK  DG   WE+E K  R+ C+   +V+E+PP+ N  +T+ V V FY+CN
Sbjct: 625 FLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN 684

Query: 668 GKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP 727
           GKRK+SQ QRFTY P    ++K E  ++ + +      S    P+P P  +Q+   P   
Sbjct: 685 GKRKKSQSQRFTYTPV---LMKQEHREEIDLS------SVPSLPVPHPAQTQR---PSSD 732

Query: 728 SSC 730
           S C
Sbjct: 733 SGC 735


>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 3 [Homo sapiens]
          Length = 1065

 Score =  559 bits (1440), Expect = e-159
 Identities = 332/663 (50%), Positives = 420/663 (63%), Gaps = 59/663 (8%)

Query: 98  GAPALESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPS 156
           G    E P I+ITS     H   +    D+++ D        PS   L LP   +YR+ S
Sbjct: 102 GPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESS 161

Query: 157 CL-SPASSLSSRSCNSEASSYESNYSYPY----------------ASPQTSPWQSP--CV 197
              SPASS+SSRS  S+ASS ES  S+ Y                 SP TSP  SP  C 
Sbjct: 162 LSPSPASSISSRSWFSDASSCES-LSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220

Query: 198 SPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNK 252
             +T   + G    L       SPR SP  SPR+SVT+E+WL  R     SSRP SPC K
Sbjct: 221 GEETWHQQYGLGHSL-------SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGK 273

Query: 253 RKYSLNGRQPPY----SPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTT 308
           R++S    +  Y    SPHHSP PSP  SPR SVT+D+WL N + +  S +  A+     
Sbjct: 274 RRHS--SAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQY 330

Query: 309 DSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGG 368
               D    +P+K+RKT+ +Q   +  K+E   +D GS  P  + + +D    Q+  K  
Sbjct: 331 CVETD----IPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKD 386

Query: 369 FC-DQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRA 427
            C DQ+L+VP  P+ W+KPKP     + + +LP LDW LP+H G  EL+IEVQPK+HHRA
Sbjct: 387 SCGDQFLSVPS-PFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRA 445

Query: 428 HYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGK 487
           HYETEGSRGAVKAS GGHP+V+L GY E +P+ LQ+FIGTADDR LRPHAFYQVHRITGK
Sbjct: 446 HYETEGSRGAVKASTGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGK 504

Query: 488 TVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRV 547
           TV+T S E I+++TKVLEIPLLPEN+M A IDCAGILKLRNSDIELRKGETDIGRKNTRV
Sbjct: 505 TVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRV 564

Query: 548 RLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHN 607
           RLVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQELP +EK S +S  V GG +MV++G N
Sbjct: 565 RLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSN 624

Query: 608 FLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN 667
           FL +SK+IF+EK  DG   WE+E K  R+ C+   +V+E+PP+ N  +T+ V V FY+CN
Sbjct: 625 FLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN 684

Query: 668 GKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP 727
           GKRK+SQ QRFTY P    ++K E  ++ + +      S    P+P P  +Q+   P   
Sbjct: 685 GKRKKSQSQRFTYTPV---LMKQEHREEIDLS------SVPSLPVPHPAQTQR---PSSD 732

Query: 728 SSC 730
           S C
Sbjct: 733 SGC 735


>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 2 [Homo sapiens]
          Length = 1068

 Score =  559 bits (1440), Expect = e-159
 Identities = 332/663 (50%), Positives = 420/663 (63%), Gaps = 59/663 (8%)

Query: 98  GAPALESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPS 156
           G    E P I+ITS     H   +    D+++ D        PS   L LP   +YR+ S
Sbjct: 102 GPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESS 161

Query: 157 CL-SPASSLSSRSCNSEASSYESNYSYPY----------------ASPQTSPWQSP--CV 197
              SPASS+SSRS  S+ASS ES  S+ Y                 SP TSP  SP  C 
Sbjct: 162 LSPSPASSISSRSWFSDASSCES-LSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220

Query: 198 SPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNK 252
             +T   + G    L       SPR SP  SPR+SVT+E+WL  R     SSRP SPC K
Sbjct: 221 GEETWHQQYGLGHSL-------SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGK 273

Query: 253 RKYSLNGRQPPY----SPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTT 308
           R++S    +  Y    SPHHSP PSP  SPR SVT+D+WL N + +  S +  A+     
Sbjct: 274 RRHS--SAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQY 330

Query: 309 DSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGG 368
               D    +P+K+RKT+ +Q   +  K+E   +D GS  P  + + +D    Q+  K  
Sbjct: 331 CVETD----IPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKD 386

Query: 369 FC-DQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRA 427
            C DQ+L+VP  P+ W+KPKP     + + +LP LDW LP+H G  EL+IEVQPK+HHRA
Sbjct: 387 SCGDQFLSVPS-PFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRA 445

Query: 428 HYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGK 487
           HYETEGSRGAVKAS GGHP+V+L GY E +P+ LQ+FIGTADDR LRPHAFYQVHRITGK
Sbjct: 446 HYETEGSRGAVKASTGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGK 504

Query: 488 TVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRV 547
           TV+T S E I+++TKVLEIPLLPEN+M A IDCAGILKLRNSDIELRKGETDIGRKNTRV
Sbjct: 505 TVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRV 564

Query: 548 RLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHN 607
           RLVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQELP +EK S +S  V GG +MV++G N
Sbjct: 565 RLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSN 624

Query: 608 FLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN 667
           FL +SK+IF+EK  DG   WE+E K  R+ C+   +V+E+PP+ N  +T+ V V FY+CN
Sbjct: 625 FLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN 684

Query: 668 GKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP 727
           GKRK+SQ QRFTY P    ++K E  ++ + +      S    P+P P  +Q+   P   
Sbjct: 685 GKRKKSQSQRFTYTPV---LMKQEHREEIDLS------SVPSLPVPHPAQTQR---PSSD 732

Query: 728 SSC 730
           S C
Sbjct: 733 SGC 735


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score =  429 bits (1104), Expect = e-120
 Identities = 331/848 (39%), Positives = 406/848 (47%), Gaps = 143/848 (16%)

Query: 25  AAAAPEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGG 83
           A   P  YG A   +  P  P P  HS  P P  +         P         +   GG
Sbjct: 110 ALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGG 160

Query: 84  PAGYFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP---- 133
           P G    +G     G   LE P I ITS            +N   + D    D  P    
Sbjct: 161 PGGGAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGF 215

Query: 134 -----------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSY 182
                       +  SPS  + SL S   + D S    A   +     SE +   S +  
Sbjct: 216 GGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGL 274

Query: 183 PYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL--- 239
                  SP  SP  SP+   PE+ +       +L G        SP     E+SWL   
Sbjct: 275 G------SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLS 314

Query: 240 ----GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWL 288
                  S RPASPC KR+YS +G     SP  S   S       P   P + +  D   
Sbjct: 315 APGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGS 374

Query: 289 GNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPP 348
                Y  +                  + +P K+R+T+ EQ  ++    EP   + G  P
Sbjct: 375 PGPFDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLP 418

Query: 349 PPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPALD 403
             A+   E  +     RK      YLAVP  P  W+K +     P+  TS     LP LD
Sbjct: 419 LGAE---ESVAPPGGSRKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPPLD 470

Query: 404 WQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQL 463
           W LPS     ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL LQ+
Sbjct: 471 WPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQM 529

Query: 464 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGI 523
           FIGTAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCAGI
Sbjct: 530 FIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGI 589

Query: 524 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELP 583
           LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQ  G+ +S+Q AS PIECSQRSAQELP
Sbjct: 590 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELP 649

Query: 584 LVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSL 643
            VE  S  +  V GG+++VL+G NFL DSKV+F+E+ PDG   WE EA  +R      +L
Sbjct: 650 QVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTL 709

Query: 644 VVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE----PA 699
            + +P + N+R++ PV V FYV NG+RKRS  Q F +LP    I K EP  D      P+
Sbjct: 710 TLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV---ICKEEPLPDSSLRGFPS 766

Query: 700 PTCGP--VSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF-----PPCPQRSTLMPAAPGVS 752
            +  P       SP   PY S     P   +  L  GF     P  PQ        P   
Sbjct: 767 ASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG----PPPSYR 822

Query: 753 PKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP----------GSPG 802
           P L        T G A P              PAV  +PRP  + P          G P 
Sbjct: 823 PGLRMFPETRGTTGCAQP--------------PAVSFLPRPFPSDPYGGRGSSFSLGLPF 868

Query: 803 QPPPALLP 810
            PP    P
Sbjct: 869 SPPAPFRP 876


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score =  429 bits (1104), Expect = e-120
 Identities = 331/848 (39%), Positives = 406/848 (47%), Gaps = 143/848 (16%)

Query: 25  AAAAPEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGG 83
           A   P  YG A   +  P  P P  HS  P P  +         P         +   GG
Sbjct: 47  ALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGG 97

Query: 84  PAGYFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP---- 133
           P G    +G     G   LE P I ITS            +N   + D    D  P    
Sbjct: 98  PGGGAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGF 152

Query: 134 -----------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSY 182
                       +  SPS  + SL S   + D S    A   +     SE +   S +  
Sbjct: 153 GGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGL 211

Query: 183 PYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL--- 239
                  SP  SP  SP+   PE+ +       +L G        SP     E+SWL   
Sbjct: 212 G------SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLS 251

Query: 240 ----GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWL 288
                  S RPASPC KR+YS +G     SP  S   S       P   P + +  D   
Sbjct: 252 APGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGS 311

Query: 289 GNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPP 348
                Y  +                  + +P K+R+T+ EQ  ++    EP   + G  P
Sbjct: 312 PGPFDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLP 355

Query: 349 PPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPALD 403
             A+   E  +     RK      YLAVP  P  W+K +     P+  TS     LP LD
Sbjct: 356 LGAE---ESVAPPGGSRKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPPLD 407

Query: 404 WQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQL 463
           W LPS     ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL LQ+
Sbjct: 408 WPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQM 466

Query: 464 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGI 523
           FIGTAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCAGI
Sbjct: 467 FIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGI 526

Query: 524 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELP 583
           LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQ  G+ +S+Q AS PIECSQRSAQELP
Sbjct: 527 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELP 586

Query: 584 LVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSL 643
            VE  S  +  V GG+++VL+G NFL DSKV+F+E+ PDG   WE EA  +R      +L
Sbjct: 587 QVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTL 646

Query: 644 VVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE----PA 699
            + +P + N+R++ PV V FYV NG+RKRS  Q F +LP    I K EP  D      P+
Sbjct: 647 TLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV---ICKEEPLPDSSLRGFPS 703

Query: 700 PTCGP--VSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF-----PPCPQRSTLMPAAPGVS 752
            +  P       SP   PY S     P   +  L  GF     P  PQ        P   
Sbjct: 704 ASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG----PPPSYR 759

Query: 753 PKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP----------GSPG 802
           P L        T G A P              PAV  +PRP  + P          G P 
Sbjct: 760 PGLRMFPETRGTTGCAQP--------------PAVSFLPRPFPSDPYGGRGSSFSLGLPF 805

Query: 803 QPPPALLP 810
            PP    P
Sbjct: 806 SPPAPFRP 813



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 52/211 (24%), Positives = 74/211 (35%), Gaps = 55/211 (26%)

Query: 633 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTY-LPANVPIIKTE 691
           TD D   P       PP+ +     P   + Y+  G         F Y +P   P  +T 
Sbjct: 711 TDMDFSPPR------PPYPSYPHEDPACETPYLSEG---------FGYGMPPLYP--QTG 753

Query: 692 PTDDYEPAPTCGPVSQG---------LSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRS 742
           P   Y P     P ++G         +S LPRP+ S          S  +   PP P R 
Sbjct: 754 PPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRP 813

Query: 743 TLMPAAP---GVSPKLHDLSPA---AYTKGVASPGHCH-LGLPQP----AGEAPAVQD-- 789
             +PA+P   G  P   D+ P     Y K    PG+    G P+      G +   +D  
Sbjct: 814 PPLPASPPLEGPFPSQSDVHPLPAEGYNK--VGPGYGPGEGAPEQEKSRGGYSSGFRDSV 871

Query: 790 -------------VPRPVATHPGSPGQPPPA 807
                        + R ++  P  PG+ PPA
Sbjct: 872 PIQGITLEEVSEIIGRDLSGFPAPPGEEPPA 902


>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
           sapiens]
          Length = 1455

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 400 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 458
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 191 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 248

Query: 459 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 518
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 249 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 306

Query: 519 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 578
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 307 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 366

Query: 579 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 638
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 367 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 423

Query: 639 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 424 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 467


>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
           sapiens]
          Length = 1531

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 400 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 458
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 267 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 324

Query: 459 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 518
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 325 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 382

Query: 519 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 578
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 383 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 442

Query: 579 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 638
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 443 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 499

Query: 639 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 500 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 543



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 47/205 (22%), Positives = 68/205 (33%), Gaps = 39/205 (19%)

Query: 34  YASSNVSPALP----LPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPA 85
           Y+  +V   LP    LP +  T  A          G  PPA    D  S   ++  GG  
Sbjct: 22  YSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGAC 81

Query: 86  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEV----------------- 128
             F +S           +S  +++ SC      +N+   + ++                 
Sbjct: 82  SSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTV 141

Query: 129 -------EDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYS 181
                  ED+L +S+ S       L S     + SC        S   N   SSY  N  
Sbjct: 142 LYISPPPEDLLDNSRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTE 196

Query: 182 YPYASPQTSPWQSPCVSPKTTDPEE 206
            P  S + +P Q P V  K  D EE
Sbjct: 197 VPRKSRKRNPKQRPGV--KRRDCEE 219


>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
           sapiens]
          Length = 1548

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 400 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 458
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 285 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 342

Query: 459 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 518
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 343 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 400

Query: 519 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 578
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 401 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 460

Query: 579 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 638
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 461 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 517

Query: 639 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 518 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 561



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 44/192 (22%), Positives = 63/192 (32%), Gaps = 35/192 (18%)

Query: 43  LPLPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPAGYFLSSGHTRPDG 98
           L LP +  T  A          G  PPA    D  S   ++  GG    F +S       
Sbjct: 53  LQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYS 112

Query: 99  APALESPRIEITSCLGLYHNNNQFFHDVEV------------------------EDVLPS 134
               +S  +++ SC      +N+   + ++                        ED+L +
Sbjct: 113 TSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDN 172

Query: 135 SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 194
           S+ S       L S     + SC        S   N   SSY  N   P  S + +P Q 
Sbjct: 173 SRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQR 227

Query: 195 PCVSPKTTDPEE 206
           P V  K  D EE
Sbjct: 228 PGV--KRRDCEE 237


>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
           sapiens]
          Length = 1549

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 400 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 458
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 285 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 342

Query: 459 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 518
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 343 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 400

Query: 519 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 578
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 401 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 460

Query: 579 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 638
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 461 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 517

Query: 639 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 518 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 561



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 44/192 (22%), Positives = 63/192 (32%), Gaps = 35/192 (18%)

Query: 43  LPLPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPAGYFLSSGHTRPDG 98
           L LP +  T  A          G  PPA    D  S   ++  GG    F +S       
Sbjct: 53  LQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYS 112

Query: 99  APALESPRIEITSCLGLYHNNNQFFHDVEV------------------------EDVLPS 134
               +S  +++ SC      +N+   + ++                        ED+L +
Sbjct: 113 TSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDN 172

Query: 135 SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 194
           S+ S       L S     + SC        S   N   SSY  N   P  S + +P Q 
Sbjct: 173 SRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQR 227

Query: 195 PCVSPKTTDPEE 206
           P V  K  D EE
Sbjct: 228 PGV--KRRDCEE 237


>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
           sapiens]
          Length = 1455

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 400 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 458
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 191 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 248

Query: 459 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 518
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 249 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 306

Query: 519 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 578
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 307 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 366

Query: 579 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 638
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 367 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 423

Query: 639 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 424 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 467


>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 2 [Homo sapiens]
          Length = 548

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 108/446 (24%), Positives = 163/446 (36%), Gaps = 64/446 (14%)

Query: 410 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 463
           SGPY   IE   +   R  Y+ EG S G++           HP ++++GY     + + L
Sbjct: 17  SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76

Query: 464 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 517
                 D   RPH     H + GK      +EA L   + +       I  + +  +   
Sbjct: 77  ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129

Query: 518 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQ-VASNPIECSQ 576
           I    I    N   E ++G+ D+      VRL F+V V  PSGR L L  V S+PI  ++
Sbjct: 130 IS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPIFDNR 184

Query: 577 R-SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK-TD 634
             +  EL +          + G +  +L      +D +V F          WE     + 
Sbjct: 185 APNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQ 238

Query: 635 RDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLPANVPIIKTE-- 691
            D+ +  ++V   PP+ +  + +PV VS  +     R+ S+   F YLP      + E  
Sbjct: 239 ADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEK 298

Query: 692 -------------------PTDDYEPAPTCGPVSQGLS------PLPRPYYSQQLAMPPD 726
                              PTD   P       S+  +      P P P+ S    +  D
Sbjct: 299 RKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYD 358

Query: 727 PSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPA 786
               +V       Q S L PA P V P+    +PA     V++       +P  A   P 
Sbjct: 359 EFPTMVFPSGQISQASALAPAPPQVLPQAP--APAPAPAMVSALAQAPAPVPVLAPGPPQ 416

Query: 787 VQDVPRPVATHPGSPGQPPPALLPQQ 812
               P P  T  G  G    ALL  Q
Sbjct: 417 AVAPPAPKPTQAGE-GTLSEALLQLQ 441


>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 1 [Homo sapiens]
          Length = 551

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 108/450 (24%), Positives = 166/450 (36%), Gaps = 69/450 (15%)

Query: 410 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 463
           SGPY   IE   +   R  Y+ EG S G++           HP ++++GY     + + L
Sbjct: 17  SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76

Query: 464 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 517
                 D   RPH     H + GK      +EA L   + +       I  + +  +   
Sbjct: 77  ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129

Query: 518 IDCAGILKLRNSD----IELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQ-VASNPI 572
           I     ++  N+     IE ++G+ D+      VRL F+V V  PSGR L L  V S+PI
Sbjct: 130 ISQR--IQTNNNPFQVPIEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPI 183

Query: 573 ECSQR-SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEA 631
             ++  +  EL +          + G +  +L      +D +V F          WE   
Sbjct: 184 FDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARG 237

Query: 632 K-TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLPANVPIIK 689
             +  D+ +  ++V   PP+ +  + +PV VS  +     R+ S+   F YLP      +
Sbjct: 238 SFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHR 297

Query: 690 TE---------------------PTDDYEPAPTCGPVSQGLS------PLPRPYYSQQLA 722
            E                     PTD   P       S+  +      P P P+ S    
Sbjct: 298 IEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLST 357

Query: 723 MPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAG 782
           +  D    +V       Q S L PA P V P+    +PA     V++       +P  A 
Sbjct: 358 INYDEFPTMVFPSGQISQASALAPAPPQVLPQAP--APAPAPAMVSALAQAPAPVPVLAP 415

Query: 783 EAPAVQDVPRPVATHPGSPGQPPPALLPQQ 812
             P     P P  T  G  G    ALL  Q
Sbjct: 416 GPPQAVAPPAPKPTQAGE-GTLSEALLQLQ 444


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 113/489 (23%), Positives = 157/489 (32%), Gaps = 99/489 (20%)

Query: 20  RDEGAAAAAPEHYGYASSNVSPAL-PLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGA 78
           + +G  A  P        + +PAL PL ++    P+P   LQ+  P  +P   H S    
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332

Query: 79  ALDGGPAGYFLSSGHTRPDGAPALE-------SPRIEITSCLGLYHNNNQFFHDVEVEDV 131
            L        L      P   P+L+       +P  + T+ LG      Q  H       
Sbjct: 333 QL-----ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG--SPTLQATH-----SF 380

Query: 132 LPSSKRSP-------STATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPY 184
           LPS   SP       +   L+LP L+A   P    P S L++ S  +  +        P+
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 440

Query: 185 ASPQTSPWQ-------SPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEES 237
           + P + P Q       SP VSP  T P +  P  L A  L   P  SP  SP  S +   
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQA-PPSLAAPPLQVPP--SPPASPPMSPSATP 497

Query: 238 WLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHG--SPRVSVTDDSWLGNTTQYT 295
              A     A P    K       PP +P    TP      SP  S    +    +    
Sbjct: 498 PPQAPPPLAAPPLQLAK------PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551

Query: 296 SSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQP--------------PSVALKVEPVG 341
            S +           +  L    P      TL+ P              P + L + P  
Sbjct: 552 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-- 609

Query: 342 EDLGSPPPP-------------------ADFAPEDYSSFQHIRKGGFC-----DQYLAVP 377
              G PPPP                   A   PE+   +    +GG       D  LA  
Sbjct: 610 ---GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA- 665

Query: 378 QHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGA 437
            HP  W++  P  P ++       L W   +  G  +    +         YETEG   A
Sbjct: 666 CHPAAWSR-GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI---------YETEGPESA 715

Query: 438 VKASAGGHP 446
             A     P
Sbjct: 716 TPAPGALDP 724



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 70/253 (27%), Positives = 99/253 (39%), Gaps = 51/253 (20%)

Query: 40  SPALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAALDGGPAGYFLSSGHTRP 96
           SPA   P+A  T  AP H  Q    G   + PP   P    AA   GP     SS    P
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS---SSPLATP 307

Query: 97  DGAPALES---PRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYR 153
             + AL+S   P +  T      H+++      ++   LP +  SPS      PSL+   
Sbjct: 308 SPSAALQSQAPPTLPATP-----HSSSL---TCQLATPLPLAPPSPSAP----PSLQTLP 355

Query: 154 DPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPR-GL 212
            P    PA+  S  + +  + + ++ +S+           SP +SP  T P +  P   L
Sbjct: 356 SP----PATPPSQATTSLGSPTLQATHSF---------LPSPPLSPLATPPPQAPPALAL 402

Query: 213 GACTLLGSPRHSPSTSPRASVTEES-------WLGARSSRPASPCNKRKYSLNGRQPPYS 265
                  SP  SP  SP A+ + ++        L A  S P SP           Q P+S
Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP---------PVQAPFS 453

Query: 266 PHHSPTPSPHGSP 278
           P  SP  SP  +P
Sbjct: 454 PPASPPVSPSATP 466



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 38/114 (33%), Positives = 44/114 (38%), Gaps = 20/114 (17%)

Query: 699 APTCGPVSQGLSPL--PRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLH 756
           AP   P S  LSPL  P P     LA+       L A F P P      P +P  SP + 
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAV-----HLLQAPFSPPPSPPVQAPFSPPASPPV- 460

Query: 757 DLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLP 810
             SP+A     A P             AP +Q  P P A+ P SP   PP   P
Sbjct: 461 --SPSATPPSQAPPSLA----------APPLQVPPSPPASPPMSPSATPPPQAP 502



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 43/140 (30%), Positives = 53/140 (37%), Gaps = 6/140 (4%)

Query: 676 QRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRP-YYSQQLAMPPDPSSCLVAG 734
           Q  T LP   P     P+    P+P   P SQ  + L  P   +    +P  P S L   
Sbjct: 333 QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 392

Query: 735 FPPCPQRSTLMP-AAPGVSPKLHDLSPAAYTKGVASPGHCHLGL---PQPAGEAPAVQDV 790
            P  P    L P  AP   P    LSP A T    +P    + L   P     +P VQ  
Sbjct: 393 PPQAPPALALPPLQAPPSPPASPPLSPLA-TPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451

Query: 791 PRPVATHPGSPGQPPPALLP 810
             P A+ P SP   PP+  P
Sbjct: 452 FSPPASPPVSPSATPPSQAP 471



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 37/116 (31%), Positives = 42/116 (36%), Gaps = 12/116 (10%)

Query: 700 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAG---FPPCPQRSTLMPAAPGVSPKLH 756
           P   PV    SP   P  S     P      L A     PP P      PA+P +SP   
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP------PASPPMSPSAT 496

Query: 757 DLSPAAYTKGVASPGHCHLGLPQ--PAGEAPAVQDVPRPVATHPGSPGQPPPALLP 810
              P A     A P       PQ  PA   P +Q +P P A+ PG     P A LP
Sbjct: 497 P-PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 19/127 (14%)

Query: 697 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRS--TLMPAAPGVSPK 754
           + AP  GP+S      P P  + Q   PP   +   +    C   +   L P +P   P 
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPS 350

Query: 755 LHDL------SPAAYTKGVASP----GHCHLGLP------QPAGEAPAVQDVPRPVATHP 798
           L  L       P+  T  + SP     H  L  P       P  +AP    +P P+   P
Sbjct: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP-PLQAPP 409

Query: 799 GSPGQPP 805
             P  PP
Sbjct: 410 SPPASPP 416



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 59/240 (24%), Positives = 81/240 (33%), Gaps = 52/240 (21%)

Query: 201 TTDPEEGFP------RGLGACTLLGSPRHSPSTSPR----------ASVTEESWLGARSS 244
           T+ P  G P      R   A T +G PR +PS  PR          +S +E S     ++
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-----TT 218

Query: 245 RPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAIN 304
            P+    +R  +  G Q P S   S + +P  SP  S            + S      + 
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278

Query: 305 AL----TTDSSLDLGDGVPVKSRKTTLEQPPSVALKVE------------PVGEDLGSPP 348
           AL     T    D    +   S        PS AL+ +             +   L +P 
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338

Query: 349 PPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPS 408
           P A  +P    S Q             +P  P   A P   + TS  SPTL A    LPS
Sbjct: 339 PLAPPSPSAPPSLQ------------TLPSPP---ATPPSQATTSLGSPTLQATHSFLPS 383


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 37/116 (31%), Positives = 52/116 (44%), Gaps = 11/116 (9%)

Query: 696 YEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKL 755
           + PAP   P + G+ P     +     + P PS+ +       PQ   + PAAP V P+ 
Sbjct: 337 HPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVH------PQAPGVHPAAPAVHPQA 390

Query: 756 HDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDV-PRPVATHPGSPGQPPPALLP 810
             + P A      +PG  H   PQP G  P+   V P+P   HP +PG  PP  +P
Sbjct: 391 PGVHPPAPGMHPQAPG-VH---PQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMP 442



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/127 (32%), Positives = 51/127 (40%), Gaps = 9/127 (7%)

Query: 681 LPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQ 740
           LPA  P +K  P       P   P+ + L P P       L +PP P +      PP P 
Sbjct: 223 LPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPP----PGGLPLPPMPPTGPAPSGPPGPP 278

Query: 741 RSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGS 800
           +  L P APGV P    + P A      +PG   +  P P    PA    P     HP +
Sbjct: 279 Q--LPPPAPGVHPPAPVVHPPASGVHPPAPG---VHPPAPGVHPPAPGVHPPTSGVHPPA 333

Query: 801 PGQPPPA 807
           PG  PPA
Sbjct: 334 PGVHPPA 340


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 114/476 (23%), Positives = 151/476 (31%), Gaps = 101/476 (21%)

Query: 40  SPALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAA-----LDGGPAGYFLSS 91
           SPA   P+A  T  AP H  Q    G   + PP   P    AA     L   P      S
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301

Query: 92  GHTRPDGAPALE-------SPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSP----- 139
               P   P+L+       +P  + T+ LG      Q  H       LPS   SP     
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLG--SPTLQATH-----SFLPSPPLSPLATPP 354

Query: 140 --STATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQ---- 193
             +   L+LP L+A   P    P S L++ S  +  +        P++ P + P Q    
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414

Query: 194 ---SPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPC 250
              SP VSP  T P +  P  L A  L   P  SP  SP  S +      A     A P 
Sbjct: 415 PPASPPVSPSATPPSQA-PPSLAAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAAPPL 471

Query: 251 NKRKYSLNGRQPPYSPHHSPTPSPHG--SPRVSVTDDSWLGNTTQYTSSAIVAAINALTT 308
              K       PP +P    TP      SP  S    +    +     S +         
Sbjct: 472 QLAK------PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525

Query: 309 DSSLDLGDGVPVKSRKTTLEQP--------------PSVALKVEPVGEDLGSPPPP---- 350
             +  L    P      TL+ P              P + L + P     G PPPP    
Sbjct: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-----GPPPPPSRSP 580

Query: 351 ---------------ADFAPEDYSSFQHIRKGGFC-----DQYLAVPQHPYQWAKPKPLS 390
                          A   PE+   +    +GG       D  LA   HP  W++  P  
Sbjct: 581 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA-CHPAAWSR-GPAP 638

Query: 391 PTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHP 446
           P ++       L W   +  G  +    +         YETEG   A  A     P
Sbjct: 639 PLAFRGAPGAPLPWPPATGPGSADGLCTI---------YETEGPESATPAPGALDP 685



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 38/114 (33%), Positives = 44/114 (38%), Gaps = 20/114 (17%)

Query: 699 APTCGPVSQGLSPL--PRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLH 756
           AP   P S  LSPL  P P     LA+       L A F P P      P +P  SP + 
Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAV-----HLLQAPFSPPPSPPVQAPFSPPASPPV- 421

Query: 757 DLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLP 810
             SP+A     A P             AP +Q  P P A+ P SP   PP   P
Sbjct: 422 --SPSATPPSQAPPSLA----------APPLQVPPSPPASPPMSPSATPPPQAP 463



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 40/134 (29%), Positives = 51/134 (38%), Gaps = 6/134 (4%)

Query: 682 PANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRP-YYSQQLAMPPDPSSCLVAGFPPCPQ 740
           P+  P     P+    P+P   P SQ  + L  P   +    +P  P S L    P  P 
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359

Query: 741 RSTLMP-AAPGVSPKLHDLSPAAYTKGVASPGHCHLGL---PQPAGEAPAVQDVPRPVAT 796
              L P  AP   P    LSP A T    +P    + L   P     +P VQ    P A+
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLA-TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418

Query: 797 HPGSPGQPPPALLP 810
            P SP   PP+  P
Sbjct: 419 PPVSPSATPPSQAP 432



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 37/116 (31%), Positives = 42/116 (36%), Gaps = 12/116 (10%)

Query: 700 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAG---FPPCPQRSTLMPAAPGVSPKLH 756
           P   PV    SP   P  S     P      L A     PP P      PA+P +SP   
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP------PASPPMSPSAT 457

Query: 757 DLSPAAYTKGVASPGHCHLGLPQ--PAGEAPAVQDVPRPVATHPGSPGQPPPALLP 810
              P A     A P       PQ  PA   P +Q +P P A+ PG     P A LP
Sbjct: 458 P-PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 34/115 (29%), Positives = 40/115 (34%), Gaps = 1/115 (0%)

Query: 692 PTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGV 751
           P+    P+P+  P  Q L   P    SQ       P+      F P P  S L    P  
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357

Query: 752 SPKLHDLSPAAYTKGVASPGHCHLGLPQP-AGEAPAVQDVPRPVATHPGSPGQPP 805
            P L      A     ASP    L  P P A  A AV  +  P +  P  P Q P
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 33/122 (27%), Positives = 44/122 (36%), Gaps = 13/122 (10%)

Query: 690 TEPTDDYEPAPTCG-----PVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTL 744
           TEP+      P+ G     P S+ LS    P  S   + P    +      P  P+   L
Sbjct: 209 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 268

Query: 745 MPAAPG-VSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQ 803
               P  V+P   D +PA      +SP      L  P+  AP     P  + T P  P  
Sbjct: 269 QALRPPQVTPPRKDAAPALGPLS-SSP------LATPSPSAPPSPSAPPSLQTLPSPPAT 321

Query: 804 PP 805
           PP
Sbjct: 322 PP 323


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 47/172 (27%), Positives = 65/172 (37%), Gaps = 23/172 (13%)

Query: 117  HNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSY 176
            HN+  F+ +         + R PS  T   PS   +R PS  S  SSL  R  +    S+
Sbjct: 1539 HNHPSFYRE--------RTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSH 1590

Query: 177  ESNYSYPYASPQTSPWQSPCVSPKTTDPEEG----FPRGLGACTLLG------SPRHSPS 226
             S     ++SP    W+SP      + PE        RGL + +            HSPS
Sbjct: 1591 CSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPS 1650

Query: 227  TSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSP 278
                 S +E S   +   R  SP  +     + R P    H SP+   H SP
Sbjct: 1651 ERSHRSPSERSHRSSSERRHRSPSQR-----SHRGPSERSHCSPSERRHRSP 1697



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 38/144 (26%), Positives = 48/144 (33%), Gaps = 19/144 (13%)

Query: 135  SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 194
            S R PS  +   PS   +R PS  S       R  +    S+ S     + SP      S
Sbjct: 1677 SHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHS 1736

Query: 195  PCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRK 254
            P      +  E                 HSPS     S +E S       R  SP  +R 
Sbjct: 1737 PSERSHHSPSERR--------------HHSPSERSHCSPSERSHCSPSERRHRSPSERRH 1782

Query: 255  YSLNGRQPPYSPHHSPTPSPHGSP 278
            +S     P    HHSP+   H SP
Sbjct: 1783 HS-----PSEKSHHSPSERSHHSP 1801



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 39/148 (26%), Positives = 49/148 (33%), Gaps = 19/148 (12%)

Query: 135  SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 194
            S RS S      PS  ++R PS  S  S    R  +    S+       + SP     +S
Sbjct: 1661 SHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRS 1720

Query: 195  PCVSPKTTDPEEGFPRGLGACTLLGSP----RHSPSTSPRASVTEESWLGARSSRPASPC 250
            P      +  E              SP     HSPS     S +E S          SP 
Sbjct: 1721 PARRSHRSPSERSHH----------SPSERSHHSPSERRHHSPSERSHCSPSERSHCSPS 1770

Query: 251  NKRKYSLNGRQPPYSPHHSPTPSPHGSP 278
             +R      R P    HHSP+   H SP
Sbjct: 1771 ERRH-----RSPSERRHHSPSEKSHHSP 1793


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 42/129 (32%), Positives = 49/129 (37%), Gaps = 23/129 (17%)

Query: 695 DYEPAPTC-GPVSQGL-SPLPRPYYSQQLAMPPD--PSSCLVAGFPPCPQRSTLMPAAPG 750
           D  P P+   PV   L S LP P      + PP   P   L  G PP      + P A G
Sbjct: 213 DAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAG 272

Query: 751 VSPKLHDLSPAAYTKGVASPGHCHL--------GLPQPAGEAPAV-----QDVPRPVATH 797
             P      P+A T G   PGH H         G+P P      +       +  P A  
Sbjct: 273 HGP------PSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGP 326

Query: 798 PGSPGQPPP 806
           PGS GQPPP
Sbjct: 327 PGSGGQPPP 335



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 9/101 (8%)

Query: 182 YPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGA 241
           +P+A P  S  Q P   P+   P  G P   G   +   PR  P  SP          G 
Sbjct: 321 HPHAGPPGSGGQPP---PR---PPPGMPHP-GPPPMGMPPRGPPFGSPMGHPGPMPPHGM 373

Query: 242 RSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSV 282
           R   P  P     Y+   R PPY     P P P  +PR  V
Sbjct: 374 RGPPPLMP--PHGYTGPPRPPPYGYQRGPLPPPRPTPRPPV 412


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 49/192 (25%), Positives = 77/192 (40%), Gaps = 24/192 (12%)

Query: 625 HVWEMEAKTDRDLCKPNSLVVEIPP--FRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
           H W    +  +D+C   S   + PP  FRN  + +        C  + K ++  +     
Sbjct: 552 HRWRGGCEERKDVCI--STDDDCPPKTFRNVCVQTDRETFLKPCESESKTTRSNQLVPKK 609

Query: 683 ANVPII-KTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQR 741
            N+  + +  P +D++       +   L P+     +QQ A+PP P+S  +   PP P  
Sbjct: 610 LNISSLSQLSPPNDHKD------IHAALQPMEGMASNQQKALPPPPAS--IPPPPPLPSG 661

Query: 742 -STLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP--AGEAPAVQDVPRPVATHP 798
             +L PA P        + P +    +  P      LP P  AG  P     P P +  P
Sbjct: 662 LGSLSPAPP--------MPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAP 713

Query: 799 GSPGQPPPALLP 810
            +PG PPPA  P
Sbjct: 714 PNPGGPPPAPPP 725


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 71/262 (27%), Positives = 91/262 (34%), Gaps = 66/262 (25%)

Query: 44  PLPTAH---STLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAP 100
           PL T H      PAPC      +P   PP + PS               S     P   P
Sbjct: 552 PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS---------------SIATPPPQAPP 596

Query: 101 ALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSP-------STATLSLPSLEAYR 153
           AL SP ++                       LPS   SP       +   L+LP L+A  
Sbjct: 597 ALASPPLQ----------------------GLPSPPLSPLATPPPQAPPXLALPPLQAPP 634

Query: 154 DPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQ-------SPCVSPKTTDPEE 206
            P    P S L++ S  +  +        P++ P + P Q       SP VSP  T P +
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694

Query: 207 GFPRGLGACTLL--GSPRHSPSTSPRASVTEES-------WLGARSSRPASPCNKRKYSL 257
             P  L A  L    SP  SP  SP A+   ++        L    S PASP      + 
Sbjct: 695 A-PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753

Query: 258 NGRQPPY--SPHHSPTPSPHGS 277
             R PP   +P     PSP  S
Sbjct: 754 PPRVPPLLAAPPLQVPPSPPAS 775



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 43/135 (31%), Positives = 50/135 (37%), Gaps = 31/135 (22%)

Query: 699 APTCGPVSQGLSPL--PRPYYSQQLAM-------PPDPSSCLVAGFPPCPQRSTLMPAAP 749
           AP   P S  LSPL  P P     LA+        P PS  + A F P        PA+P
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP--------PASP 683

Query: 750 GVSPKLHDLSPAAYTKGV----------ASPGHCHLGLPQPAGE----APAVQDVPRPVA 795
            VSP     S A  +             ASP       P P       AP +Q  P P A
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743

Query: 796 THPGSPGQPPPALLP 810
           + P SP   PP  +P
Sbjct: 744 SPPMSPSATPPPRVP 758



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 37/121 (30%), Positives = 50/121 (41%), Gaps = 12/121 (9%)

Query: 697 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSC--LVAGFPPCPQRST---LMPAAPGV 751
           + AP  GP+S      P P  ++   +PP  ++   L A  PP P  +T   L P +P  
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350

Query: 752 SPKLHDL-SPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP-GSPG-QPPPAL 808
            P L  L SP A     A P         P    P++Q +P     H   SP  Q PP+ 
Sbjct: 351 PPSLQTLPSPPATPPSQAPPSM----TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406

Query: 809 L 809
           L
Sbjct: 407 L 407



 Score = 37.0 bits (84), Expect = 0.073
 Identities = 102/389 (26%), Positives = 136/389 (34%), Gaps = 80/389 (20%)

Query: 40  SPALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAALDGGPAGYFLSS---GH 93
           SPA   P+A  T  AP H  Q    G   + PP   P    AA   GP    LSS     
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP----LSSSPLAT 306

Query: 94  TRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYR 153
             P G  A   P                           P +  +P  AT  LP      
Sbjct: 307 PSPSGTKARPVPP--------------------------PDNAATPLPAT--LPPSPPLA 338

Query: 154 DPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSP---------CVSPKTTDP 204
            P  L+P S  +  S  +  S   +  S    S  T P Q+P          V    T P
Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSP 398

Query: 205 EEGFP------RGLGACTLLGSP----RHSPST-SPR---ASVTEESWLGARSSRPASPC 250
               P        L A T LGSP     HS  T SPR   AS+T  S     S+ P SP 
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS--RPASTPPDSPP 456

Query: 251 NKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAI--NALTT 308
            +   SL    PP     SP  SP  SP +++     L +   ++  A ++++    L T
Sbjct: 457 LQAPLSLPA-SPPLQTSLSPAVSPLSSP-LTIHPLQALSSLASHSPQAPLSSLIMPPLET 514

Query: 309 DSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGG 368
            SSL             +L+ PP+ +L   P+       PPP   A    ++  H+    
Sbjct: 515 QSSL----------APPSLQTPPA-SLTTPPLENLPSLAPPPLQTASAPLTT-PHLETPP 562

Query: 369 FCDQYLAVPQHPYQWAKPKPLSPTSYMSP 397
            C     +   P     P P +P+S  +P
Sbjct: 563 -CPAPCPLQAPPSPLTTPPPETPSSIATP 590



 Score = 37.0 bits (84), Expect = 0.073
 Identities = 43/150 (28%), Positives = 49/150 (32%), Gaps = 23/150 (15%)

Query: 682 PANVPIIKTEPTDDYEPA----PTCGPVSQGLSPL--PRPYYSQQLAMPPDPSSCLVAGF 735
           P   P     P     PA    P  G  S  LSPL  P P     LA+PP  +       
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639

Query: 736 PPCPQRSTLMPAAPGV---------------SPKLHDLSPAAYTKGVASPGHCHLGLPQP 780
           PP    +T  P AP                  P     SP A      SP         P
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA--SPPVSPSATPPSQAPP 697

Query: 781 AGEAPAVQDVPRPVATHPGSPGQPPPALLP 810
           +  AP +Q  P P A+ P SP   PP   P
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAP 727



 Score = 36.6 bits (83), Expect = 0.096
 Identities = 37/135 (27%), Positives = 53/135 (39%), Gaps = 12/135 (8%)

Query: 682 PANVPIIKTEPTDDYEPAPTCGP-VSQGLSPLPR---PYYSQQLAMPPDPSSCLVAGFPP 737
           P+  P     P     P+P   P +S   +P P+   P  +  L +PP P +      PP
Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS-----PP 746

Query: 738 CPQRSTLMPAAPGV--SPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVA 795
               +T  P  P +  +P L  + P+       SP         PA   P +Q +P P A
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQ-VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805

Query: 796 THPGSPGQPPPALLP 810
           + PG     P A LP
Sbjct: 806 SFPGQAPFSPSASLP 820



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 48/163 (29%), Positives = 65/163 (39%), Gaps = 25/163 (15%)

Query: 132 LPSSKRSP---STATLSLPSLEAYRDPS---CLSPASSLSSRSCNSEASSYESNYSYP-- 183
           LPS    P   ++A L+ P LE    P+     +P S L++    + +S        P  
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597

Query: 184 YASPQTSPWQSPCVSPKTTDPEEGFPR-GLGACTLLGSPRHSPSTSPRASVTEES----- 237
            ASP      SP +SP  T P +  P   L       SP  SP  SP A+ + ++     
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657

Query: 238 --WLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSP 278
              L A  S P SP           Q P+SP  SP  SP  +P
Sbjct: 658 VHLLQAPFSPPPSP---------PVQAPFSPPASPPVSPSATP 691



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 31/109 (28%), Positives = 40/109 (36%), Gaps = 19/109 (17%)

Query: 700 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS 759
           P   P  +  +P   P  S  LA P  PS       PP    +T +PA    SP L    
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATP-SPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341

Query: 760 PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPAL 808
           P A               P      P++Q +P P AT    P Q PP++
Sbjct: 342 PLA---------------PPSPSAPPSLQTLPSPPAT---PPSQAPPSM 372



 Score = 30.8 bits (68), Expect = 5.3
 Identities = 56/232 (24%), Positives = 76/232 (32%), Gaps = 45/232 (19%)

Query: 201 TTDPEEGFP------RGLGACTLLGSPRHSPSTSPR----------ASVTEESWLGARSS 244
           T+ P  G P      R   A T +G PR +PS  PR          +S +E S     ++
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-----TT 218

Query: 245 RPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAIN 304
            P+    +R  +  G Q P S   S + +P  SP  S            + S      + 
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278

Query: 305 ALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHI 364
           AL            P K     L    S  L           P PP D A     +    
Sbjct: 279 ALRPPQVTP-----PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA---- 329

Query: 365 RKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSP----TLPALDWQLPSHSGP 412
                      +P  P   A P PL+P S  +P    TLP+     PS + P
Sbjct: 330 ----------TLPPSP-PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 54/185 (29%), Positives = 79/185 (42%), Gaps = 29/185 (15%)

Query: 138 SPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCV 197
           SPS +  S+PS     D    SP++S +S   NS  +S+ ++++   + P  S W SP  
Sbjct: 38  SPSASGASIPS-----DSGWASPSASGASTPSNSGWASFSASWA---SIPSDSGWASPSA 89

Query: 198 SPKTTDPEEGF--PRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKY 255
           S  +T  + G+  P   GA     S   SPS S  AS+    W        ASP      
Sbjct: 90  SWASTPSDSGWASPSASGASIPSDSGWASPSVS-GASIPSAFW--------ASP------ 134

Query: 256 SLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTS-SAIVAAINALTTDSSLDL 314
           S +G     +P  S   SP  S   + +D  W   +  +TS SA  A+ +A    +  D 
Sbjct: 135 SASGAS---TPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDS 191

Query: 315 GDGVP 319
           G   P
Sbjct: 192 GWASP 196



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 73/271 (26%), Positives = 106/271 (39%), Gaps = 28/271 (10%)

Query: 24  AAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGG 83
           + A+ P   G+AS +VS A  +P+A    P        S  G   P+D  SG+ A+    
Sbjct: 106 SGASIPSDSGWASPSVSGA-SIPSAFWASP--------SASGASTPSD--SGW-ASPSAS 153

Query: 84  PAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTAT 143
            A     SG   P  +    S     +S  G    ++  +    V  V      SPST+ 
Sbjct: 154 WASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSGWASPSVFWV------SPSTSW 207

Query: 144 LSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYS-YPYASPQTSPWQSPCVSPKTT 202
            S PS   +      S  +S SS SC S ++S  S  S   +ASP  S W S   S  +T
Sbjct: 208 ASSPSDFGWASTPSDSGWAS-SSASCISPSASGASTSSDSGWASPSAS-WVSTSTSRAST 265

Query: 203 DPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARS-SRPASPCNKRKYSLN-GR 260
             + G+     +   + S       S   + +  SW  A S S  +SP   R  +L+   
Sbjct: 266 SSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSG 325

Query: 261 QPPYSPHHSPTPS-----PHGSPRVSVTDDS 286
              +S   +  PS      H +  VS T DS
Sbjct: 326 WASFSASGASAPSDSGWTSHSASGVSTTSDS 356


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 46/133 (34%), Positives = 49/133 (36%), Gaps = 27/133 (20%)

Query: 692  PTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP-----SSCLVAGFPPCPQRSTLMP 746
            P     P P C PV     PLP PY     A  P P     SS + AGFP          
Sbjct: 899  PNPTPAPPPPCFPVPPP-QPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFP---------- 947

Query: 747  AAP--GVSPKLHDLSPAAYTKGVASPG------HCHLGLPQPAGEAPAVQDVPRPVATHP 798
             AP  G  P+ H     +   G   P       H HL  PQ  G  P     P P A  P
Sbjct: 948  -APRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQS--PYPYAPQP 1004

Query: 799  GSPGQPPPALLPQ 811
            G  GQPPP L  Q
Sbjct: 1005 GVLGQPPPPLHTQ 1017



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 19/128 (14%)

Query: 698 PAPTCGPVSQGLSPLPRPYYSQQLAMPPDPS------SCLVAGFPPCPQRSTLMPAAPG- 750
           P P   PV+ G +  P P Y+ +L + P  S      S    G  P P  + L  A P  
Sbjct: 808 PGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQ 867

Query: 751 -VSPKL-HDLSPAAYT-KGVASPGHCHL--------GLPQPAGEAPAVQDVPRPVATHPG 799
              P+L   + PA  T   + +P   H           P P    P  Q +P P  T+P 
Sbjct: 868 FSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPY-TYPA 926

Query: 800 SPGQPPPA 807
              QP PA
Sbjct: 927 GAKQPIPA 934



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 12/110 (10%)

Query: 711 PLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDL---------SPA 761
           P PRP   + L    + S  + AG PP   RS  +P      P+L D           P 
Sbjct: 716 PPPRPTAPKPLLPRREESEAVEAGDPPEELRS--LPPDMVAGPRLPDTFLGSATPLHFPP 773

Query: 762 AYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP-GSPGQPPPALLP 810
           +       PG  +L  P P G       + +P A  P   P  P PAL P
Sbjct: 774 SPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYP 823


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,497,439
Number of Sequences: 37866
Number of extensions: 2590275
Number of successful extensions: 11041
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 472
Number of HSP's that attempted gapping in prelim test: 9076
Number of HSP's gapped (non-prelim): 2102
length of query: 812
length of database: 18,247,518
effective HSP length: 111
effective length of query: 701
effective length of database: 14,044,392
effective search space: 9845118792
effective search space used: 9845118792
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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