Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 27363458
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27363458 leucine rich repeat and fibronectin type III domain
containing 4 [Homo sapiens]
(635 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27363458 leucine rich repeat and fibronectin type III domain ... 1289 0.0
gi|55741571 leucine rich repeat and fibronectin type III domain ... 626 e-179
gi|13375646 leucine rich repeat and fibronectin type III domain ... 593 e-169
gi|31542244 leucine rich repeat and fibronectin type III domain ... 572 e-163
gi|149773484 leucine rich repeat and fibronectin type III domain... 560 e-159
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 162 9e-40
gi|52138725 leucine rich repeat and Ig domain containing 4 [Homo... 147 4e-35
gi|51317373 netrin-G1 ligand [Homo sapiens] 139 8e-33
gi|157426829 leucine rich repeat and Ig domain containing 3 [Hom... 134 3e-31
gi|15029530 leucine rich repeat containing 4 [Homo sapiens] 130 3e-30
gi|126517478 peroxidasin homolog-like [Homo sapiens] 130 5e-30
gi|88702793 slit-like 2 [Homo sapiens] 129 1e-29
gi|109150416 peroxidasin [Homo sapiens] 127 2e-29
gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens] 126 5e-29
gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens] 126 5e-29
gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 124 2e-28
gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo... 122 8e-28
gi|194306623 immunoglobulin superfamily containing leucine-rich ... 122 1e-27
gi|194306621 immunoglobulin superfamily containing leucine-rich ... 122 1e-27
gi|39930401 immunoglobulin superfamily containing leucine-rich r... 122 1e-27
gi|194306618 immunoglobulin superfamily containing leucine-rich ... 122 1e-27
gi|193083136 leucine-rich repeat, immunoglobulin-like and transm... 113 5e-25
gi|41582239 immunoglobulin superfamily containing leucine-rich r... 113 5e-25
gi|5031809 immunoglobulin superfamily containing leucine-rich re... 113 5e-25
gi|62988340 leucine rich repeat containing 22 [Homo sapiens] 113 6e-25
gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens] 112 1e-24
gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens] 112 1e-24
gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens] 112 1e-24
gi|50263044 leucine-rich repeat neuronal 6A [Homo sapiens] 107 3e-23
gi|153791330 leucine rich repeat neuronal 1 [Homo sapiens] 105 2e-22
>gi|27363458 leucine rich repeat and fibronectin type III domain
containing 4 [Homo sapiens]
Length = 635
Score = 1289 bits (3336), Expect = 0.0
Identities = 635/635 (100%), Positives = 635/635 (100%)
Query: 1 MAPPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFI 60
MAPPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFI
Sbjct: 1 MAPPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFI 60
Query: 61 QALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPV 120
QALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPV
Sbjct: 61 QALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPV 120
Query: 121 NLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNL 180
NLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNL
Sbjct: 121 NLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNL 180
Query: 181 IDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNC 240
IDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNC
Sbjct: 181 IDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNC 240
Query: 241 ELLWLRRLARPDDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATL 300
ELLWLRRLARPDDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATL
Sbjct: 241 ELLWLRRLARPDDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATL 300
Query: 301 RCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEA 360
RCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEA
Sbjct: 301 RCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEA 360
Query: 361 TARVELRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTATSGL 420
TARVELRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTATSGL
Sbjct: 361 TARVELRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTATSGL 420
Query: 421 VSWGPGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCLLALSPA 480
VSWGPGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCLLALSPA
Sbjct: 421 VSWGPGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCLLALSPA 480
Query: 481 AGPSDLTATRLLGCAHFSTLPASPLCHALQAHVLGGTLTVAVGGVLVAALLVFTVALLVR 540
AGPSDLTATRLLGCAHFSTLPASPLCHALQAHVLGGTLTVAVGGVLVAALLVFTVALLVR
Sbjct: 481 AGPSDLTATRLLGCAHFSTLPASPLCHALQAHVLGGTLTVAVGGVLVAALLVFTVALLVR 540
Query: 541 GRGAGNGRLPLKLSHVQSQTNGGPSPTPKAHPPRSPPPRPQRSCSLDLGDAGCYGYARRL 600
GRGAGNGRLPLKLSHVQSQTNGGPSPTPKAHPPRSPPPRPQRSCSLDLGDAGCYGYARRL
Sbjct: 541 GRGAGNGRLPLKLSHVQSQTNGGPSPTPKAHPPRSPPPRPQRSCSLDLGDAGCYGYARRL 600
Query: 601 GGAWARRSHSVHGGLLGAGCRGVGGSAERLEESVV 635
GGAWARRSHSVHGGLLGAGCRGVGGSAERLEESVV
Sbjct: 601 GGAWARRSHSVHGGLLGAGCRGVGGSAERLEESVV 635
>gi|55741571 leucine rich repeat and fibronectin type III domain
containing 2 [Homo sapiens]
Length = 789
Score = 626 bits (1615), Expect = e-179
Identities = 346/651 (53%), Positives = 430/651 (66%), Gaps = 39/651 (5%)
Query: 9 LLASGAA-----ACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQAL 63
LLA G A ACP CVCQNLSESL TLC +GLLFVPP++DRRTVELRL NFI +
Sbjct: 8 LLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHI 67
Query: 64 GPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQ 123
DF NMTGLVDLTLSRN I+ I +F DLESLRSLHLD NRL LG +LRG VNLQ
Sbjct: 68 SRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQ 127
Query: 124 HLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDA 183
HLI++ NQLG IA AF+DFL +LEDLDLSYNNL +PW + M LH L+LDHNL+D
Sbjct: 128 HLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDH 187
Query: 184 LPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDA--EASP--APLVLSFSGNPLHCN 239
+ G FA L +L+RLDLTSNRL L PDP+F+R + + A+P PL SF GNPLHCN
Sbjct: 188 IAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCN 247
Query: 240 CELLWLRRLARPDDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRAT 299
CELLWLRRL R DDLETC SP GL GRYFW V E EF CEPPLI +HT +L VLEGQ AT
Sbjct: 248 CELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAAT 307
Query: 300 LRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGE 359
L+C+A+GDP+P +HWV PDDRLVGNSSR + NGTL+I +T + D+G +TCIA N AGE
Sbjct: 308 LKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDIFITTSQDSGAFTCIAANAAGE 367
Query: 360 ATARVELRVLALPHGGNSSAEGGRPGP--SDIAASARTAAEGEGTLESEP-------AVQ 410
ATA VE+ ++ LPH NS++ P SDI S++T+ G G+ EP AV
Sbjct: 368 ATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVL 427
Query: 411 VTEVTATSGLVSWGPGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADY 470
V+EVT TS LV W + A V M+Q+QYN S+DE LIYR++PAS+ F++ +LV G Y
Sbjct: 428 VSEVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGY 487
Query: 471 DLCLLALSPAAGPSDLTATRLLGCAHFSTLPASPLCHALQAHVLGGTLTVAVGGVLVAAL 530
DLC+LA+ + LTAT ++GCA F T P C ++ + +LGGT+ + +GG++VA L
Sbjct: 488 DLCVLAMWDDTA-TTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATL 546
Query: 531 LVFTVALLVRGRGAGN---GRLPLKLSHVQSQTNGG----PSPTPKAHPPRSPPPRPQRS 583
LVF V L+VR + + ++ +S+V SQTNG PS P PP+ PP R+
Sbjct: 547 LVFIVILMVRYKVCNHEAPSKMAAAVSNVYSQTNGAQPPPPSSAPAGAPPQGPPKVVVRN 606
Query: 584 CSLDLGDAGCYGYARRLGGAWARRSHSVHGGLLGAG-CRGVGGSAERLEES 633
LD + AR S S LG+G G+G + R+ S
Sbjct: 607 ELLD------------FTASLARASDSSSSSSLGSGEAAGLGRAPWRIPPS 645
Score = 38.5 bits (88), Expect = 0.019
Identities = 39/116 (33%), Positives = 49/116 (42%), Gaps = 28/116 (24%)
Query: 541 GRGAGNGRLPLKLSHVQSQTNGGPSPTPKAHPPRSPPPRP-----QRSCSLDLGD----- 590
GRGAG S ++ P P A RS P P +RS S D+GD
Sbjct: 681 GRGAGT-------SARGHHSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAA 733
Query: 591 -----AGCYGYARRLGGAWARRSHSVHGGLLG------AGCRGVGGSAERLEESVV 635
G Y R++ W +RS SV+G LL G RG GS+E + ES V
Sbjct: 734 AGGVVPGGYSPPRKVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV 789
>gi|13375646 leucine rich repeat and fibronectin type III domain
containing 3 [Homo sapiens]
Length = 628
Score = 593 bits (1530), Expect = e-169
Identities = 327/603 (54%), Positives = 396/603 (65%), Gaps = 33/603 (5%)
Query: 4 PLLLLLLASGAAA----------CPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVEL 53
PLLL LL A+ CP C CQ S LS LC GLLFVPP++DRR EL
Sbjct: 5 PLLLCLLPLAPASSPPQSATPSPCPRRCRCQTQSLPLSVLCPGAGLLFVPPSLDRRAAEL 64
Query: 54 RLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGT 113
RLADNFI ++ D NMTGL+ L+LSRN I + A AF DL +LR+LHLDGNRL LG
Sbjct: 65 RLADNFIASVRRRDLANMTGLLHLSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLGE 124
Query: 114 GSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHT 173
G LRG VNL+HLILS NQL +A GA DD E+LEDLDLSYNNL Q+PW +G + ++T
Sbjct: 125 GQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNNLEQLPWEALGRLGNVNT 184
Query: 174 LNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSR----GRDAEASPAPLVL 229
L LDHNL+ ++P GAF++L +L+RLD+TSNRL T+ PDPLFSR R + + LVL
Sbjct: 185 LGLDHNLLASVPAGAFSRLHKLARLDMTSNRLTTIPPDPLFSRLPLLARPRGSPASALVL 244
Query: 230 SFSGNPLHCNCELLWLRRLARPDDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQR 289
+F GNPLHCNCEL+WLRRLAR DDLE CASPP L GRYFWAV E EF CEPP++ +
Sbjct: 245 AFGGNPLHCNCELVWLRRLAREDDLEACASPPALGGRYFWAVGEEEFVCEPPVVTHRSPP 304
Query: 290 LWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGY 349
L V G+ A LRCRA+GDP P + WV P RL+GNSSRARAFPNGTLE+ VT GD G +
Sbjct: 305 LAVPAGRPAALRCRAVGDPEPRVRWVSPQGRLLGNSSRARAFPNGTLELLVTEPGDGGIF 364
Query: 350 TCIATNPAGEATARVELRVLALPH---GGNSSAEGGRPG-------PSDIAASARTAAEG 399
TCIA N AGEATA VEL V P ++S + R G PS +ASA+ A G
Sbjct: 365 TCIAANAAGEATAAVELTVGPPPPPQLANSTSCDPPRDGDPDALTPPSAASASAKVADTG 424
Query: 400 EGTLESEPAVQVTEVTATSGLVSWGPGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHF 459
T + VQVTE AT+ LV W RP + M+QIQYNSS D+ L+YR++PA S F
Sbjct: 425 PPT---DRGVQVTEHGATAALVQWPDQRPIPGIRMYQIQYNSSADDILVYRMIPAESRSF 481
Query: 460 LLKHLVPGADYDLCLLALSPAAGPSDLTATRLLGCAHFSTLPASPLCHALQAHVLGGTLT 519
LL L G YDLC+LA+ + + LTATR +GCA FST PA C A A LGGT+
Sbjct: 482 LLTDLASGRTYDLCVLAVYEDSA-TGLTATRPVGCARFSTEPALRPCGAPHAPFLGGTMI 540
Query: 520 VAVGGVLVAALLVFTVALLVR-----GRGAGNGRLPLKLSHVQSQTNGGPSPTPKAHPPR 574
+A+GGV+VA++LVF LL+R G+ G ++P +S V SQTNG PTP PP
Sbjct: 541 IALGGVIVASVLVFIFVLLMRYKVHGGQPPGKAKIPAPVSSVCSQTNGALGPTPTPAPPA 600
Query: 575 SPP 577
P
Sbjct: 601 PEP 603
>gi|31542244 leucine rich repeat and fibronectin type III domain
containing 5 [Homo sapiens]
Length = 719
Score = 572 bits (1473), Expect = e-163
Identities = 294/570 (51%), Positives = 389/570 (68%), Gaps = 14/570 (2%)
Query: 5 LLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALG 64
L L+ +A A CP CVCQ LS +L+TLCA +GLLFVPPN+DRRTVELRLADNF+ +
Sbjct: 8 LFLIGIAVKAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIK 67
Query: 65 PPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQH 124
DF NMT LVDLTLSRN I+ I AF DL +LR+LHL+ NRL ++ G NL H
Sbjct: 68 RKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHH 127
Query: 125 LILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDAL 184
LIL+ NQL I+ AFDD +LE+LDLSYNNL +PW + M +LHTL+LDHN+ID +
Sbjct: 128 LILNNNQLTLISSTAFDDVF-ALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNI 186
Query: 185 PPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGR----DAEASPAPLVLSFSGNPLHCNC 240
P G F+ L +++RLD+TSN+L L PDPLF R + SP+ LSF GNPLHCNC
Sbjct: 187 PKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNC 246
Query: 241 ELLWLRRLARPDDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATL 300
ELLWLRRL+R DDLETCASPP L GRYFW++PE EF CEPPLI RHT + VLEGQRATL
Sbjct: 247 ELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATL 306
Query: 301 RCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEA 360
RC+A GDP P +HW+ P+ +L+ N++R+ + NGTL+I +T D G +TCIA+NPAGEA
Sbjct: 307 RCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEA 366
Query: 361 TARVELRVLALPHGGNSS--AEGGRPGPSDIAASAR----TAAEGEGTLESEPAVQVTEV 414
T V+L ++ LPH NS+ PG SDI+ S + T++ T S+ + V E
Sbjct: 367 TQIVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNTSSSNGDTKLSQDKIVVAEA 426
Query: 415 TATSGLVSWGPGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCL 474
T+++ L+ + R + MFQIQYN + D+TL+YR++P +S FL+ +L G YDLC+
Sbjct: 427 TSSTALLKFNFQRNIPGIRMFQIQYNGTYDDTLVYRMIPPTSKTFLVNNLAAGTMYDLCV 486
Query: 475 LALSPAAGPSDLTATRLLGCAHFSTLPASPLCHALQAHVLGGTLTVAVGGVLVAALLVFT 534
LA+ G + LTATR++GC F+T CH +Q+ LGGT+ + +GG++VA++LVF
Sbjct: 487 LAIYD-DGITSLTATRVVGCIQFTTEQDYVRCHFMQSQFLGGTMIIIIGGIIVASVLVFI 545
Query: 535 VALLVRGRGAGNG--RLPLKLSHVQSQTNG 562
+ L++R + N K+S+V SQTNG
Sbjct: 546 IILMIRYKVCNNNGQHKVTKVSNVYSQTNG 575
>gi|149773484 leucine rich repeat and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 771
Score = 560 bits (1444), Expect = e-159
Identities = 305/590 (51%), Positives = 384/590 (65%), Gaps = 21/590 (3%)
Query: 2 APPLLLLLLASGAAACPLP--CVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNF 59
A P LLLL A + P P C+CQN++ +L+ LCA GLLFVPP +DRR VELRL DNF
Sbjct: 17 ALPFLLLLWAGASRGQPCPGRCICQNVAPTLTMLCAKTGLLFVPPAIDRRVVELRLTDNF 76
Query: 60 IQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGP 119
I A+ DF NMT LV LTLSRN I ++ A AF DL +LR+LHLD NRL E+ LRG
Sbjct: 77 IAAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGL 136
Query: 120 VNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHN 179
NL+HLIL NQ+ R+ AFD FL ++EDLDLSYNNL +PW +G M L+TL LDHN
Sbjct: 137 GNLRHLILGNNQIRRVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHN 196
Query: 180 LIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGR-DAEASPAPLVLSFSGNPLHC 238
LID + G F QL +L RLD+TSNRL L PD LF R + P PL +SF GNPLHC
Sbjct: 197 LIDHIAEGTFVQLHKLVRLDMTSNRLHKLPPDGLFLRSQGTGPKPPTPLTVSFGGNPLHC 256
Query: 239 NCELLWLRRLARPDDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHT-QRLWVLEGQR 297
NCELLWLRRL R DDLETCA+P L RYFW++PE EF CEPPLI R R V+EGQ
Sbjct: 257 NCELLWLRRLTREDDLETCATPEHLTDRYFWSIPEEEFLCEPPLITRQAGGRALVVEGQA 316
Query: 298 ATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPA 357
+LRCRA+GDP P +HWV PD RL+GNSSR R +GTL++ +T D+G +TCIA+N A
Sbjct: 317 VSLRCRAVGDPEPVVHWVAPDGRLLGNSSRTRVRGDGTLDVTITTLRDSGTFTCIASNAA 376
Query: 358 GEATARVELRVLALPHGGNSSAEG---GRPGPSDIAASARTAAEGEGTLESEPAVQVTEV 414
GEATA VE+ V+ LP A PG SDIA R A +E + E+
Sbjct: 377 GEATAPVEVCVVPLPLMAPPPAAPPPLTEPGSSDIATPGRPGANDSA---AERRLVAAEL 433
Query: 415 TATSGLVSWGPGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCL 474
T+ S L+ W RP + M+Q+QYNSS D++L+YR++P++S FL+ L G YDLC+
Sbjct: 434 TSNSVLIRWPAQRPVPGIRMYQVQYNSSVDDSLVYRMIPSTSQTFLVNDLAAGRAYDLCV 493
Query: 475 LALSPAAGPSDLTATRLLGCAHFSTLPASPLCHALQAHVLGGTLTVAVGGVLVAALLVFT 534
LA+ G + L ATR++GC F+T C L+AH LGGT+ +A+GGV+VA++LVF
Sbjct: 494 LAVYD-DGATALPATRVVGCVQFTTAGDPAPCRPLRAHFLGGTMIIAIGGVIVASVLVFI 552
Query: 535 VALLVRGRGAGNG--------RLPLKLSHVQSQTNGGPSPTPKAHPPRSP 576
V L++R + G+G R ++SHV SQTNG + T A P P
Sbjct: 553 VLLMIRYKVYGDGDSRRVKGSRSLPRVSHVCSQTNG--AGTGAAQAPALP 600
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 162 bits (410), Expect = 9e-40
Identities = 143/482 (29%), Positives = 209/482 (43%), Gaps = 71/482 (14%)
Query: 14 AAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRNMTG 73
A +CP+ C C N ++ +C R L VP ++ T L L +N IQ + F+++
Sbjct: 54 ATSCPVACSCSN--QASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRH 111
Query: 74 LVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGNQLG 133
L L LS+N + +I AF L SL +L L NRL + T + L+ L L N +
Sbjct: 112 LEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIE 171
Query: 134 RIAPGAFD------------------------DFLESLEDLDLSYNNLRQVPWAGIGAMP 169
I AF+ + L +L L+L NL+ +P + A+
Sbjct: 172 SIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDIP--NLTALV 229
Query: 170 ALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATL---APDPLFS------RGRDA 220
L L L N +D + PG+F L L +L L ++AT+ A D L S +
Sbjct: 230 RLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNL 289
Query: 221 EASPAPLV--------LSFSGNPLHCNCELLWLR---RLARPDDLETCA---SPPGLAGR 266
+ P L + + NP HCNC++LWL + P + CA +P GL GR
Sbjct: 290 MSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWLKETVPSNTTCCARCHAPAGLKGR 349
Query: 267 YFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSS 326
Y + + F+C P+I L V EG A L+CR G +++W+ P+ L+ + S
Sbjct: 350 YIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRT-GTSMTSVNWLTPNGTLMTHGS 408
Query: 327 ---RARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVELRVLA---LPHGGNSSAE 380
R +GTL D G YTC+ TN AG TA L V A + GG S
Sbjct: 409 YRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTASATLNVSAVDPVAAGGTGSGG 468
Query: 381 GGRPGPSDIAASAR-----TAAEGEGTLESEPAVQVTEVTATS----GLVS---WGPGRP 428
GG G + + T E TLE++P + + T G + WG GRP
Sbjct: 469 GGPGGSGGVGGGSGGYTYFTTVTVE-TLETQPGEEALQPRGTEKEPPGPTTDGVWGGGRP 527
Query: 429 AD 430
D
Sbjct: 528 GD 529
>gi|52138725 leucine rich repeat and Ig domain containing 4 [Homo
sapiens]
Length = 593
Score = 147 bits (370), Expect = 4e-35
Identities = 128/410 (31%), Positives = 183/410 (44%), Gaps = 42/410 (10%)
Query: 52 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVEL 111
+L + DN + + P F + L LTL R ++ + A L +L +L L + L
Sbjct: 160 KLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRL 219
Query: 112 GTGSLRGPVNLQHL-ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPA 170
G+LRG L+ L I L + PG+ +L L ++ NL VP+ + +
Sbjct: 220 PAGALRGLGQLKELEIHLWPSLEALDPGSLVGL--NLSSLAITRCNLSSVPFQALYHLSF 277
Query: 171 LHTLNLDHNLIDALPPGAFAQLGQLSRL----------------DLTSNRLATLAPDPLF 214
L L+L N I A+P + L +L L LT+ L +A + L
Sbjct: 278 LRVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQ 337
Query: 215 SRGRDAEASPAPLV-LSFSGNPLHCNCELLWLRRLARPDDL----ETCASPPGLAGR--- 266
+ A SP LV L SGNPL C+C LLWL RL R D CA P + G+
Sbjct: 338 TLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRHLDFGMSPPACAGPHHVQGKSLK 397
Query: 267 -YFWAVPEGEFSCEPPLIARHTQRLWVL--EGQRATLRCRALGDPAPTMHWVGPDDRLVG 323
+ +P G F+C+P LI + R WV+ EG A C GDPAPT+ W+ P +G
Sbjct: 398 EFSDILPPGHFTCKPALIRKSGPR-WVIAEEGGHAVFSCSGDGDPAPTVSWMRPHGAWLG 456
Query: 324 NSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVELRVLAL--PHGGNSSAE- 380
+ R R +GTLEI D G Y C+ +N AG + R L V+ + P+G S
Sbjct: 457 RAGRVRVLEDGTLEIRSVQLRDRGAYVCVVSNVAGNDSLRTWLEVIQVEPPNGTLSDPNI 516
Query: 381 --GGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTATSGLVS-WGPGR 427
G PGP + + G L +T VT GL++ W G+
Sbjct: 517 TVPGIPGPFFLDSRGVAMVLAVGFLPF-----LTSVTLCFGLIALWSKGK 561
Score = 94.7 bits (234), Expect = 2e-19
Identities = 76/222 (34%), Positives = 98/222 (44%), Gaps = 25/222 (11%)
Query: 3 PPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQA 62
PPLL LLL G + P VC S+ + LC HR L VP + T L L+ N +
Sbjct: 15 PPLLFLLLLPGGSGGSCPAVCDCTSQPQAVLCGHRQLEAVPGGLPLDTELLDLSGNRLWG 74
Query: 63 LGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPV-- 120
L ++ L +L LS N ++ + AF L+SL +L L GNRL +G G G
Sbjct: 75 LQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSAL 134
Query: 121 ----------------------NLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLR 158
+LQ L + N L +APGAF L L L L NL
Sbjct: 135 TLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAG-LAKLSTLTLERCNLS 193
Query: 159 QVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDL 200
VP + +PAL L L I LP GA LGQL L++
Sbjct: 194 TVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEI 235
Score = 53.5 bits (127), Expect = 6e-07
Identities = 37/103 (35%), Positives = 55/103 (53%), Gaps = 3/103 (2%)
Query: 103 LDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPW 162
L G+R +E G L P++ + L LSGN+L + G L L++LDLSYN L +
Sbjct: 45 LCGHRQLEAVPGGL--PLDTELLDLSGNRLWGLQQGMLSR-LSLLQELDLSYNQLSTLEP 101
Query: 163 AGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRL 205
+ +L TL L N + + PG F+ L L+ LDL N++
Sbjct: 102 GAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQI 144
>gi|51317373 netrin-G1 ligand [Homo sapiens]
Length = 640
Score = 139 bits (350), Expect = 8e-33
Identities = 126/434 (29%), Positives = 182/434 (41%), Gaps = 80/434 (18%)
Query: 4 PLLLLLLASG---------AAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELR 54
PLL++LLA A CP C C N + +C + L VP + T L
Sbjct: 25 PLLVVLLALQLLVVAGLVRAQTCPSVCSCSN--QFSKVICVRKNLREVPDGISTNTRLLN 82
Query: 55 LADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTG 114
L +N IQ + F+++ L L LSRN I I AF L +L +L L NRL + G
Sbjct: 83 LHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNG 142
Query: 115 SLRGPVNLQHLILSGN-------------------------QLGRIAPGAFDDFLESLED 149
+ L+ L L N +L I+ GAF+ L +L
Sbjct: 143 AFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEG-LSNLRY 201
Query: 150 LDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRL----------- 198
L+L+ NLR++P + + L L+L N + A+ PG+F L L +L
Sbjct: 202 LNLAMCNLREIP--NLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIE 259
Query: 199 -------------DLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNCELLWL 245
+L N L TL P LF+ E + NP +CNC++LWL
Sbjct: 260 RNAFDNLQSLVEINLAHNNL-TLLPHDLFTPLHHLER------IHLHHNPWNCNCDILWL 312
Query: 246 R---RLARPDDLETCA---SPPGLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRAT 299
+ P + CA +PP L GRY + + F+C P+I L V EG A
Sbjct: 313 SWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAE 372
Query: 300 LRCRALGDPAPTMHWVGPDDRLVGNSS---RARAFPNGTLEIGVTGAGDAGGYTCIATNP 356
L+CRA ++ W+ P+ ++ + + R +GTL D G YTC+ +N
Sbjct: 373 LKCRA-STSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNS 431
Query: 357 AGEATARVELRVLA 370
G TA L V A
Sbjct: 432 VGNTTASATLNVTA 445
>gi|157426829 leucine rich repeat and Ig domain containing 3 [Homo
sapiens]
Length = 592
Score = 134 bits (336), Expect = 3e-31
Identities = 109/357 (30%), Positives = 153/357 (42%), Gaps = 31/357 (8%)
Query: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
L + DN + + F + L +LTL R +T + + G L SL +L L + L
Sbjct: 155 LEVGDNDLVFVSRRAFAGLLALEELTLERCNLTALSGESLGHLRSLGALRLRHLAIASLE 214
Query: 113 TGSLRGPVNLQHLILSG-NQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPAL 171
+ R L HL + L +A G+ +L L +++ N+ VP A + L
Sbjct: 215 DQNFRRLPGLLHLEIDNWPLLEEVAAGSLRGL--NLTSLSVTHTNITAVPAAALRHQAHL 272
Query: 172 HTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLS- 230
LNL HN I +P G+F L +L L L LA + P + + + +LS
Sbjct: 273 TCLNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLRQIRLLNLSNNLLST 332
Query: 231 ----------------FSGNPLHCNCELLWL----RRLARPDDLETCASPPGLAGRYFWA 270
GNPL C+C LLW+ + L L CA+P + G
Sbjct: 333 LEESTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDALRN 392
Query: 271 VPEGE----FSCEPPLIA-RHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNS 325
+P+ F C P I R QR+ G+ CRA G+PAPT+ WV P R V +
Sbjct: 393 LPDSVLFEYFVCRKPKIRERRLQRVTATAGEDVRFLCRAEGEPAPTVAWVTPQHRPVTAT 452
Query: 326 S--RARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVELRVLALPHGGNSSAE 380
S RAR P GTLEI D+G YTC+A+N G T L V P + E
Sbjct: 453 SAGRARVLPGGTLEIQDARPQDSGTYTCVASNAGGNDTYFATLTVRPEPAANRTPGE 509
Score = 81.6 bits (200), Expect = 2e-15
Identities = 70/206 (33%), Positives = 94/206 (45%), Gaps = 4/206 (1%)
Query: 4 PLLLLLLASG-AAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQA 62
PLLLL A A CP C C + +++ C R L VP + T L L+ N I+
Sbjct: 11 PLLLLPAAPPPAGGCPARCECTVQTRAVA--CTRRRLTAVPDGIPAETRLLELSRNRIRC 68
Query: 63 LGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNL 122
L P D + L +L LS NAI + AF +L LR L L GN+L + G NL
Sbjct: 69 LNPGDLAALPALEELDLSENAIAHVEPGAFANLPRLRVLRLRGNQLKLIPPGVFTRLDNL 128
Query: 123 QHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLID 182
L LS N+L + F D L SL L++ N+L V + AL L L+ +
Sbjct: 129 TLLDLSENKLVILLDYTFQD-LHSLRRLEVGDNDLVFVSRRAFAGLLALEELTLERCNLT 187
Query: 183 ALPPGAFAQLGQLSRLDLTSNRLATL 208
AL + L L L L +A+L
Sbjct: 188 ALSGESLGHLRSLGALRLRHLAIASL 213
Score = 45.1 bits (105), Expect = 2e-04
Identities = 28/67 (41%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Query: 150 LDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLA 209
L+LS N +R + + A+PAL L+L N I + PGAFA L +L L L N+L L
Sbjct: 59 LELSRNRIRCLNPGDLAALPALEELDLSENAIAHVEPGAFANLPRLRVLRLRGNQL-KLI 117
Query: 210 PDPLFSR 216
P +F+R
Sbjct: 118 PPGVFTR 124
>gi|15029530 leucine rich repeat containing 4 [Homo sapiens]
Length = 653
Score = 130 bits (328), Expect = 3e-30
Identities = 114/413 (27%), Positives = 174/413 (42%), Gaps = 66/413 (15%)
Query: 11 ASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRN 70
++G CP C C N + +C RGL VP + T L L +N IQ + FR+
Sbjct: 40 SAGPQNCPSVCSCSN--QFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRH 97
Query: 71 MTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGN 130
+ L L L RN+I +I AF L SL +L L N L + +G+ L+ L L N
Sbjct: 98 LHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNN 157
Query: 131 -------------------------QLGRIAPGAFDDF---------------------L 144
+L I+ GAF+ L
Sbjct: 158 PIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLTPL 217
Query: 145 ESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNR 204
LE+L++S N+ ++ + +L L + ++ + + AF L L L+L N
Sbjct: 218 VGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNN 277
Query: 205 LATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNCELLWLRRLAR---PDDLETCA--- 258
L++L P LF+ R + L NP +C+C++LWL R P + C
Sbjct: 278 LSSL-PHDLFTPLRYL------VELHLHHNPWNCDCDILWLAWWLREYIPTNSTCCGRCH 330
Query: 259 SPPGLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPD 318
+P + GRY V + F C P I + L + EG+ A L+CR P ++ W+ P+
Sbjct: 331 APMHMRGRYLVEVDQASFQCSAPFIMDAPRDLNISEGRMAELKCRT--PPMSSVKWLLPN 388
Query: 319 DRLVGNSS---RARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVELRV 368
++ ++S R +GTL D G YTC+ TN AG + A L V
Sbjct: 389 GTVLSHASRHPRISVLNDGTLNFSHVLLSDTGVYTCMVTNVAGNSNASAYLNV 441
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 130 bits (326), Expect = 5e-30
Identities = 110/374 (29%), Positives = 155/374 (41%), Gaps = 66/374 (17%)
Query: 8 LLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPD 67
L L +G LPC + L + C H L +P V ++T L L N I+ +
Sbjct: 11 LFLLAGWCLPGLPCPSRCLCFKSTVRCMHLMLDHIP-QVPQQTTVLDLRFNRIREIPGSA 69
Query: 68 FRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLIL 127
F+ + L L L+ N I +I AF LE+L L+L N + L + +G ++L+HL +
Sbjct: 70 FKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLYI 129
Query: 128 SGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPG 187
NQL + P F D L L L L +N + +P G
Sbjct: 130 HFNQLEMLQPETFGDLLR-------------------------LERLFLHNNKLSKIPAG 164
Query: 188 AFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNCELLWLRR 247
+F+ L L RL L SN L C+C+L+WL
Sbjct: 165 SFSNLDSLKRLRLDSNALV-------------------------------CDCDLMWLGE 193
Query: 248 LAR-------PDDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATL 300
L + TC P L GR +V EF+C+ P I Q + V G
Sbjct: 194 LLQGFAQHGHTQAAATCEYPRRLHGRAVASVTVEEFNCQSPRITFEPQDVEVPSGNTVYF 253
Query: 301 RCRALGDPAPTMHWVGPDDRL-VGNSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGE 359
CRA G+P P + W+ + L + + +R F +GTL I T D G Y C+A N AGE
Sbjct: 254 TCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGE 313
Query: 360 A-TARVELRVLALP 372
A T LR +LP
Sbjct: 314 AKTQSAMLRYSSLP 327
Score = 41.6 bits (96), Expect = 0.002
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
Query: 295 GQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTCIAT 354
G+ + C A G+P P + W + + S + GTL I G D G Y C+A
Sbjct: 525 GKNINISCHAQGEPQPIITW-NKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRYECVAR 583
Query: 355 NPAGEATARVELRVLAL 371
N G A + L V A+
Sbjct: 584 NSFGLAVTNMFLTVTAI 600
Score = 33.9 bits (76), Expect = 0.47
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 1/77 (1%)
Query: 292 VLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTC 351
VLE C A G+P P + W +L +GTL I D G Y C
Sbjct: 430 VLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHT-VLSSGTLRIDRAAQHDQGQYEC 488
Query: 352 IATNPAGEATARVELRV 368
A + G V+L V
Sbjct: 489 QAVSSLGVKKVSVQLTV 505
>gi|88702793 slit-like 2 [Homo sapiens]
Length = 673
Score = 129 bits (323), Expect = 1e-29
Identities = 176/673 (26%), Positives = 246/673 (36%), Gaps = 148/673 (21%)
Query: 1 MAPPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFI 60
+ P LLLL L G CP C C S+ + C R VP +V TV L + +N I
Sbjct: 8 LLPLLLLLALGPGVQGCPSGCQC---SQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGI 64
Query: 61 QALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPV 120
L F + GL L LS+N I + + F L +L +L L NRL E+ + RG
Sbjct: 65 TMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLR 124
Query: 121 NLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNL 180
L+ L L N++ I PGAFD L+ L +L L N LR +P +P L L+L HN
Sbjct: 125 RLERLYLGKNRIRHIQPGAFDT-LDRLLELKLQDNELRALPPL---RLPRLLLLDLSHNS 180
Query: 181 IDALPP-----------------------GAFAQLGQLSRLDLTSNRLATLAPDPLFSRG 217
+ AL P G F++L L LD++ N+L + P RG
Sbjct: 181 LLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRG 240
Query: 218 ----------RDAEASPAPL-------------------------------VLSFSGNPL 236
R A+ P L +L+ + NP
Sbjct: 241 LTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPF 300
Query: 237 HCNCELLWLR--------RLARPDDLETCASPPGLAGRYFWAVPEGEFSC---------- 278
+C C L W LA P++ C PP AGR + +F C
Sbjct: 301 NCVCPLSWFGPWVRESHVTLASPEETR-CHFPPKNAGRLLLELDYADFGCPATTTTATVP 359
Query: 279 -------EPPLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAF 331
EP ++ W+ + AT A P+ VGP +
Sbjct: 360 TTRPVVREPTALSSSLAPTWLSPTEPAT---EAPSPPSTAPPTVGPVPQ------PQDCP 410
Query: 332 PNGTLEIGVTGAGDAGGYTCIATNPAGEATARVELRVLALPHGGNSSAEGGRPGPSDIAA 391
P+ L G G C+ P G E + +G RP P+ +
Sbjct: 411 PSTCLNGGTCHLGTRHHLACLC--PEGFTGLYCE----------SQMGQGTRPSPTPVTP 458
Query: 392 SARTAAEGEGTLESEPAVQVTEVTATSGLVSWGPGRPADPVWMFQIQYN--SSEDETLIY 449
+ TL EP V+ + GL + G + ++ Y S D+ L+
Sbjct: 459 RPPRSL----TLGIEP---VSPTSLRVGLQRYLQGSSVQ-LRSLRLTYRNLSGPDKRLVT 510
Query: 450 RIVPASSHHFLLKHLVPGADYDLCLLALSPAAGPSDLTATRLLGCAHFSTLPASPLCHAL 509
+PAS + + L P A Y +C++ L P P A C T PA HA
Sbjct: 511 LRLPASLAEYTVTQLRPNATYSVCVMPLGPGRVPEGEEA-----CGEAHTPPAVHSNHAP 565
Query: 510 QAHVLGGTLTV----AVGGVLVAALLVFTVALLV-RGRG----------AGNGRLPLKLS 554
G L + A+ VL+AAL A V RGR G G PL+L
Sbjct: 566 VTQAREGNLPLLIAPALAAVLLAALAAVGAAYCVRRGRAMAAAAQDKGQVGPGAGPLELE 625
Query: 555 HVQSQTNGGPSPT 567
V+ GP T
Sbjct: 626 GVKVPLEPGPKAT 638
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 127 bits (320), Expect = 2e-29
Identities = 95/281 (33%), Positives = 130/281 (46%), Gaps = 17/281 (6%)
Query: 101 LHLDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQV 160
L L NR+ E+ G+ R NL L+L+ NQ+ RI GAF+D LE+L+ L L N ++ +
Sbjct: 67 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFED-LENLKYLYLYKNEIQSI 125
Query: 161 PWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDA 220
+ +L L L N I+ L P +F L +L RL L +NR+ L P F+
Sbjct: 126 DRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGT-FNHLESM 184
Query: 221 EASPAPLVLSFSGNPLHCNCELLWLRRLARP-------DDLETCASPPGLAGRYFWAVPE 273
+ L N LHC+CE+LWL L + C P + GR +
Sbjct: 185 KR------LRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITP 238
Query: 274 GEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRL-VGNSSRARAFP 332
E +CE P I Q V G CRA G+P P + W+ ++ L + SR
Sbjct: 239 EELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLD 298
Query: 333 NGTLEIGVTGAGDAGGYTCIATNPAGEA-TARVELRVLALP 372
+GTL I T D G Y C+A N AGE T V LR P
Sbjct: 299 DGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSP 339
Score = 102 bits (255), Expect = 8e-22
Identities = 115/424 (27%), Positives = 167/424 (39%), Gaps = 72/424 (16%)
Query: 6 LLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGP 65
L ++ A CP C+C + C H LL P V +T L L N I+ + P
Sbjct: 25 LAVVAQKPGAGCPSRCLCFRTT----VRCMHL-LLEAVPAVAPQTSILDLRFNRIREIQP 79
Query: 66 PDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
FR + L L L+ N I RI + AF DLE+L+ L+L N + + + +G +L+ L
Sbjct: 80 GAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQL 139
Query: 126 ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHN------ 179
L NQ+ + P +F L LE L L N + + + ++ L LD N
Sbjct: 140 YLHFNQIETLDPDSFQH-LPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTLHCDC 198
Query: 180 ----LIDALPPGAFAQLGQLSRL-----DLTSNRLATLAPDPLFSRGRDAEASPAPLVLS 230
L D L A + Q + + + +AT+ P+ L + P ++
Sbjct: 199 EILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCERPRITSEPQDADVT 258
Query: 231 FSGNPLHCNC--------ELLWLR-----------RLARPDD--------------LETC 257
SGN ++ C E++WLR RL DD + C
Sbjct: 259 -SGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQC 317
Query: 258 ASPPGLAG---------RYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDP 308
+ +AG RYF + F +P Q VL G+ TL C A G P
Sbjct: 318 MAK-NVAGEVKTQEVTLRYFGSPARPTFVIQP-------QNTEVLVGESVTLECSATGHP 369
Query: 309 APTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVELRV 368
P + W D + R P+G L I GD+G Y C ATN A + V
Sbjct: 370 PPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIV 429
Query: 369 LALP 372
ALP
Sbjct: 430 QALP 433
Score = 47.0 bits (110), Expect = 5e-05
Identities = 29/88 (32%), Positives = 37/88 (42%), Gaps = 1/88 (1%)
Query: 281 PLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGV 340
P+ A V G L C + G+P P + W D V S + P G L I
Sbjct: 525 PVFASIPSDTTVEVGANVQLPCSSQGEPEPAITW-NKDGVQVTESGKFHISPEGFLTIND 583
Query: 341 TGAGDAGGYTCIATNPAGEATARVELRV 368
G DAG Y C+A N G A+ + L V
Sbjct: 584 VGPADAGRYECVARNTIGSASVSMVLSV 611
Score = 42.0 bits (97), Expect = 0.002
Identities = 37/129 (28%), Positives = 51/129 (39%), Gaps = 12/129 (9%)
Query: 292 VLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTC 351
V+EGQ +C A G+P P + W +L R +GTL I D G Y C
Sbjct: 444 VIEGQTVDFQCEAKGNPPPVIAWTKGGSQL-SVDRRHLVLSSGTLRISGVALHDQGQYEC 502
Query: 352 IATNPAGEATARVELRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEGTLESEPA--- 408
A N G + +V + P A ++ A+ + +G E EPA
Sbjct: 503 QAVNIIG--SQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQG--EPEPAITW 558
Query: 409 ----VQVTE 413
VQVTE
Sbjct: 559 NKDGVQVTE 567
>gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 126 bits (317), Expect = 5e-29
Identities = 148/557 (26%), Positives = 224/557 (40%), Gaps = 93/557 (16%)
Query: 52 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVEL 111
EL L N + + P F ++ L+ L L+ N + I +R F L +L L + GN++ +
Sbjct: 145 ELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAI 204
Query: 112 GTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPAL 171
+ R NL+ L+L+G L I+ A + L+SLE L N L +VP + +P L
Sbjct: 205 LDMNFRPLANLRSLVLAGMNLREISDYALEG-LQSLESLSFYDNQLARVPRRALEQVPGL 263
Query: 172 HTLNLDHNLIDALPPGAFA-------------------------QLGQLSRLDLTSN-RL 205
L+L+ N + + PG FA L +L++LD+T+N RL
Sbjct: 264 KFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRL 323
Query: 206 ATLAPDPLFS-----------------RGRDAEASPAPLVLSFSGNPLHCNCELLWLR-- 246
+ + P + E+ P + GNP+ C+C + W
Sbjct: 324 SFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANAT 383
Query: 247 ----RLARPDDLETCASPPGLAGRYFWAVPEGEFS--CEPPLIAR-HTQRLWVLEGQRAT 299
R P CA PP L VP E + C P + R L V G+
Sbjct: 384 GTRVRFIEPQS-TLCAEPPDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMV 442
Query: 300 LRCRALGDPAPTMHWVGPDD-RLVGNSS--RARAFPNGTLEIGVTGAGDAGGYTCIATNP 356
L CRAL +P P ++WV P RL + R R +P GTLE+ A +AG YTC+A N
Sbjct: 443 LHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAGLYTCVAQNL 502
Query: 357 AGEATARVELRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTA 416
G T V + V G + + GR EG+G ++V E
Sbjct: 503 VGADTKTVSVVV------GRALLQPGRD-------------EGQGL-----ELRVQETHP 538
Query: 417 TSGLVSW--GPGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCL 474
L+SW P + + + T + R+ P +H + + L+ +Y CL
Sbjct: 539 YHILLSWVTPPNTVSTNLTWSSASSLRGQGATALARL-PRGTHSYNITRLLQATEYWACL 597
Query: 475 LALSPAAGPSDLTATRLLGCAHFSTLPASPLCHALQAHVLGGTLTVAVGGVLVAALLVFT 534
+ A L C T A+ CH G +A+ +L+AA L
Sbjct: 598 QV-------AFADAHTQLACVWARTKEATS-CHRALGDRPGLIAILALAVLLLAAGLAAH 649
Query: 535 VALLVRGRGAGNGRLPL 551
+ +G G GR PL
Sbjct: 650 LGTGQPRKGVG-GRRPL 665
Score = 83.2 bits (204), Expect = 7e-16
Identities = 72/227 (31%), Positives = 98/227 (43%), Gaps = 19/227 (8%)
Query: 1 MAPPLLLLLLASGAAA---------CPLPCVCQ---------NLSESLSTLCAHRGLLFV 42
+ PLLL +A AA CP C CQ + E+ + C L V
Sbjct: 4 LVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAV 63
Query: 43 PPNVDRRTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLH 102
PP + T L L N I + + + L +L LS+N+ + F L L SLH
Sbjct: 64 PPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLH 123
Query: 103 LDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPW 162
L+ N+L L S G +LQ L L+ NQL RIAP AF L +L L L+ N LR +
Sbjct: 124 LEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSG-LSNLLRLHLNSNLLRAIDS 182
Query: 163 AGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLA 209
+P L L + N +DA+ F L L L L L ++
Sbjct: 183 RWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 119 PVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDH 178
P Q L+L N + R+ +L +L +LDLS N+ A+P L +L+L+
Sbjct: 68 PAGTQTLLLQSNSIVRVDQSELG-YLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEE 126
Query: 179 NLIDALPPGAFAQLGQLSRLDLTSNRLATLAP 210
N + L +FA L L L L N+L +AP
Sbjct: 127 NQLTRLEDHSFAGLASLQELYLNHNQLYRIAP 158
>gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 126 bits (317), Expect = 5e-29
Identities = 148/557 (26%), Positives = 224/557 (40%), Gaps = 93/557 (16%)
Query: 52 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVEL 111
EL L N + + P F ++ L+ L L+ N + I +R F L +L L + GN++ +
Sbjct: 145 ELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAI 204
Query: 112 GTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPAL 171
+ R NL+ L+L+G L I+ A + L+SLE L N L +VP + +P L
Sbjct: 205 LDMNFRPLANLRSLVLAGMNLREISDYALEG-LQSLESLSFYDNQLARVPRRALEQVPGL 263
Query: 172 HTLNLDHNLIDALPPGAFA-------------------------QLGQLSRLDLTSN-RL 205
L+L+ N + + PG FA L +L++LD+T+N RL
Sbjct: 264 KFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRL 323
Query: 206 ATLAPDPLFS-----------------RGRDAEASPAPLVLSFSGNPLHCNCELLWLR-- 246
+ + P + E+ P + GNP+ C+C + W
Sbjct: 324 SFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANAT 383
Query: 247 ----RLARPDDLETCASPPGLAGRYFWAVPEGEFS--CEPPLIAR-HTQRLWVLEGQRAT 299
R P CA PP L VP E + C P + R L V G+
Sbjct: 384 GTRVRFIEPQS-TLCAEPPDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMV 442
Query: 300 LRCRALGDPAPTMHWVGPDD-RLVGNSS--RARAFPNGTLEIGVTGAGDAGGYTCIATNP 356
L CRAL +P P ++WV P RL + R R +P GTLE+ A +AG YTC+A N
Sbjct: 443 LHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAGLYTCVAQNL 502
Query: 357 AGEATARVELRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTA 416
G T V + V G + + GR EG+G ++V E
Sbjct: 503 VGADTKTVSVVV------GRALLQPGRD-------------EGQGL-----ELRVQETHP 538
Query: 417 TSGLVSW--GPGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCL 474
L+SW P + + + T + R+ P +H + + L+ +Y CL
Sbjct: 539 YHILLSWVTPPNTVSTNLTWSSASSLRGQGATALARL-PRGTHSYNITRLLQATEYWACL 597
Query: 475 LALSPAAGPSDLTATRLLGCAHFSTLPASPLCHALQAHVLGGTLTVAVGGVLVAALLVFT 534
+ A L C T A+ CH G +A+ +L+AA L
Sbjct: 598 QV-------AFADAHTQLACVWARTKEATS-CHRALGDRPGLIAILALAVLLLAAGLAAH 649
Query: 535 VALLVRGRGAGNGRLPL 551
+ +G G GR PL
Sbjct: 650 LGTGQPRKGVG-GRRPL 665
Score = 83.2 bits (204), Expect = 7e-16
Identities = 72/227 (31%), Positives = 98/227 (43%), Gaps = 19/227 (8%)
Query: 1 MAPPLLLLLLASGAAA---------CPLPCVCQ---------NLSESLSTLCAHRGLLFV 42
+ PLLL +A AA CP C CQ + E+ + C L V
Sbjct: 4 LVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAV 63
Query: 43 PPNVDRRTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLH 102
PP + T L L N I + + + L +L LS+N+ + F L L SLH
Sbjct: 64 PPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLH 123
Query: 103 LDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPW 162
L+ N+L L S G +LQ L L+ NQL RIAP AF L +L L L+ N LR +
Sbjct: 124 LEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSG-LSNLLRLHLNSNLLRAIDS 182
Query: 163 AGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLA 209
+P L L + N +DA+ F L L L L L ++
Sbjct: 183 RWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 119 PVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDH 178
P Q L+L N + R+ +L +L +LDLS N+ A+P L +L+L+
Sbjct: 68 PAGTQTLLLQSNSIVRVDQSELG-YLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEE 126
Query: 179 NLIDALPPGAFAQLGQLSRLDLTSNRLATLAP 210
N + L +FA L L L L N+L +AP
Sbjct: 127 NQLTRLEDHSFAGLASLQELYLNHNQLYRIAP 158
>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
Length = 513
Score = 124 bits (312), Expect = 2e-28
Identities = 119/390 (30%), Positives = 154/390 (39%), Gaps = 62/390 (15%)
Query: 4 PLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQAL 63
PLLLLLL AA CP C C S + C L VP + T L L DN I L
Sbjct: 10 PLLLLLLPLRAAGCPAACRCY----SATVECGALRLRVVPLGIPPGTQTLFLQDNNIARL 65
Query: 64 GPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQ 123
P + L L L N++ + A AF L L L NRL L +G+ G L+
Sbjct: 66 EPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLR 125
Query: 124 HLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDA 183
L L+GNQL R+ LD ++ +L P L L+L N I+
Sbjct: 126 VLYLAGNQLARL--------------LDFTFLHL-----------PRLQELHLQENSIEL 160
Query: 184 LPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNCELL 243
L A A L L+ LDL+ N+L T++ + L + + VL + NP C+C L
Sbjct: 161 LEDQALAGLSSLALLDLSRNQLGTISREAL-------QPLASLQVLRLTENPWRCDCALH 213
Query: 244 WL---------RRLARPDDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLE 294
WL R L D CA PP LA + V C PP + L
Sbjct: 214 WLGAWIKEGGQRLLTSRDRKIMCAEPPRLALQSLLDVSHSSLICIPPSVHVQPLELTANL 273
Query: 295 GQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGD--------- 345
G+ + C+A G P P + W G G L +G A D
Sbjct: 274 GEDLRVACQASGYPQPLVTWRKVPQPREGRPRAQAQLEGGLLGLGGHSASDTGSGMLFLS 333
Query: 346 ------AGGYTCIATNPAGEATARVELRVL 369
AG Y C A+N G ARV R+L
Sbjct: 334 NITLAHAGKYECEASNAGG--AARVPFRLL 361
>gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo
sapiens]
Length = 606
Score = 122 bits (307), Expect = 8e-28
Identities = 107/346 (30%), Positives = 151/346 (43%), Gaps = 33/346 (9%)
Query: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
L + DN + + F + L LTL + +T + A L SL SLHL + +
Sbjct: 158 LEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMP 217
Query: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172
+ + +L+HL + L + P A + +L L ++ NL VP+ + L
Sbjct: 218 VYAFKRLFHLKHLEIDYWPLLDMMP-ANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLT 276
Query: 173 TLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDP----------------LFSR 216
LNL +N I + G F+ L +L L + +L T+ P L +
Sbjct: 277 HLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETL 336
Query: 217 GRDAEASPAPL-VLSFSGNPLHCNCELLWLRRLARPDDLE------TCASPPGLAGRYFW 269
+ +SP L VLS + NPL C+C LLW+ L R L+ CA P + R F
Sbjct: 337 EENVFSSPRALEVLSINNNPLACDCRLLWI--LQRQPTLQFGGQQPMCAGPDTIRERSFK 394
Query: 270 AVPEGE----FSCEPPLIA-RHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGN 324
F+C+ P I + Q L V EGQ L C A GDP P + WV P R +
Sbjct: 395 DFHSTALSFYFTCKKPKIREKKLQHLLVDEGQTVQLECSADGDPQPVISWVTPRRRFITT 454
Query: 325 SSRARA--FPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVELRV 368
S RA +GTLEI D+G Y CIA+N AG T L V
Sbjct: 455 KSNGRATVLGDGTLEIRFAQDQDSGMYVCIASNAAGNDTFTASLTV 500
Score = 84.0 bits (206), Expect = 4e-16
Identities = 66/228 (28%), Positives = 103/228 (45%), Gaps = 25/228 (10%)
Query: 6 LLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGP 65
++L+ CP C C ++S+S C R L+ +P + T L L+ N ++++ P
Sbjct: 17 VVLIFMGSTIGCPARCECSAQNKSVS--CHRRRLIAIPEGIPIETKILDLSKNRLKSVNP 74
Query: 66 PDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
+F + L ++ LS N I + AF +L +LRSL L GNRL + G G NL L
Sbjct: 75 EEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKL 134
Query: 126 ILSGNQLGRIAPGAFDDF-----------------------LESLEDLDLSYNNLRQVPW 162
+S N++ + F D L SLE L L NL VP
Sbjct: 135 DISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPT 194
Query: 163 AGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAP 210
+ + +L +L+L H I+ +P AF +L L L++ L + P
Sbjct: 195 EALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMP 242
>gi|194306623 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 122 bits (305), Expect = 1e-27
Identities = 122/464 (26%), Positives = 175/464 (37%), Gaps = 121/464 (26%)
Query: 6 LLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGP 65
L+ L A +CP PC C + CA++ L VP +
Sbjct: 9 LVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLP------------------ 50
Query: 66 PDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
+ L+LS N IT + AF D+ + SL L
Sbjct: 51 ------ANVTTLSLSANKITVLRRGAFADVTQVTSLWL---------------------- 82
Query: 126 ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALP 185
+ N++ + PGA L L++LDLS+N + PW+ + + AL L ++HN + +LP
Sbjct: 83 --AHNEVRTVEPGALA-VLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
Query: 186 PGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNCELLWL 245
A L L L + +NRL TLAP +A A L NP HC C L+WL
Sbjct: 140 RDALGALPDLRSLRINNNRLRTLAPGTF-------DALSALSHLQLYHNPFHCGCGLVWL 192
Query: 246 R------RLARPD-DLETCASPPGLAGRYFW-------AVPEGEFSCEPPLIARHTQRLW 291
+ R++ P+ D CASPP L G + A P S EPPL A T
Sbjct: 193 QAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAEPPLEAPGTP--- 249
Query: 292 VLEGQRATLRCRALGDPAPTMHW----------------VGPDDRLVGN----------- 324
+ G L C A G P P + W G DD +
Sbjct: 250 LRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLL 309
Query: 325 -------------------SSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVE 365
+ R A NG+L + + A +AG YTC A N G + +
Sbjct: 310 TQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIR 369
Query: 366 LRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEG--TLESEP 407
+ V A ++ GG P + ++ A+G G L S+P
Sbjct: 370 VAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKP 413
>gi|194306621 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 122 bits (305), Expect = 1e-27
Identities = 122/464 (26%), Positives = 175/464 (37%), Gaps = 121/464 (26%)
Query: 6 LLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGP 65
L+ L A +CP PC C + CA++ L VP +
Sbjct: 9 LVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLP------------------ 50
Query: 66 PDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
+ L+LS N IT + AF D+ + SL L
Sbjct: 51 ------ANVTTLSLSANKITVLRRGAFADVTQVTSLWL---------------------- 82
Query: 126 ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALP 185
+ N++ + PGA L L++LDLS+N + PW+ + + AL L ++HN + +LP
Sbjct: 83 --AHNEVRTVEPGALA-VLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
Query: 186 PGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNCELLWL 245
A L L L + +NRL TLAP +A A L NP HC C L+WL
Sbjct: 140 RDALGALPDLRSLRINNNRLRTLAPGTF-------DALSALSHLQLYHNPFHCGCGLVWL 192
Query: 246 R------RLARPD-DLETCASPPGLAGRYFW-------AVPEGEFSCEPPLIARHTQRLW 291
+ R++ P+ D CASPP L G + A P S EPPL A T
Sbjct: 193 QAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAEPPLEAPGTP--- 249
Query: 292 VLEGQRATLRCRALGDPAPTMHW----------------VGPDDRLVGN----------- 324
+ G L C A G P P + W G DD +
Sbjct: 250 LRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLL 309
Query: 325 -------------------SSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVE 365
+ R A NG+L + + A +AG YTC A N G + +
Sbjct: 310 TQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIR 369
Query: 366 LRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEG--TLESEP 407
+ V A ++ GG P + ++ A+G G L S+P
Sbjct: 370 VAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKP 413
>gi|39930401 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 122 bits (305), Expect = 1e-27
Identities = 122/464 (26%), Positives = 175/464 (37%), Gaps = 121/464 (26%)
Query: 6 LLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGP 65
L+ L A +CP PC C + CA++ L VP +
Sbjct: 9 LVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLP------------------ 50
Query: 66 PDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
+ L+LS N IT + AF D+ + SL L
Sbjct: 51 ------ANVTTLSLSANKITVLRRGAFADVTQVTSLWL---------------------- 82
Query: 126 ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALP 185
+ N++ + PGA L L++LDLS+N + PW+ + + AL L ++HN + +LP
Sbjct: 83 --AHNEVRTVEPGALA-VLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
Query: 186 PGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNCELLWL 245
A L L L + +NRL TLAP +A A L NP HC C L+WL
Sbjct: 140 RDALGALPDLRSLRINNNRLRTLAPGTF-------DALSALSHLQLYHNPFHCGCGLVWL 192
Query: 246 R------RLARPD-DLETCASPPGLAGRYFW-------AVPEGEFSCEPPLIARHTQRLW 291
+ R++ P+ D CASPP L G + A P S EPPL A T
Sbjct: 193 QAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAEPPLEAPGTP--- 249
Query: 292 VLEGQRATLRCRALGDPAPTMHW----------------VGPDDRLVGN----------- 324
+ G L C A G P P + W G DD +
Sbjct: 250 LRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLL 309
Query: 325 -------------------SSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVE 365
+ R A NG+L + + A +AG YTC A N G + +
Sbjct: 310 TQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIR 369
Query: 366 LRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEG--TLESEP 407
+ V A ++ GG P + ++ A+G G L S+P
Sbjct: 370 VAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKP 413
>gi|194306618 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 122 bits (305), Expect = 1e-27
Identities = 122/464 (26%), Positives = 175/464 (37%), Gaps = 121/464 (26%)
Query: 6 LLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGP 65
L+ L A +CP PC C + CA++ L VP +
Sbjct: 9 LVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLP------------------ 50
Query: 66 PDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
+ L+LS N IT + AF D+ + SL L
Sbjct: 51 ------ANVTTLSLSANKITVLRRGAFADVTQVTSLWL---------------------- 82
Query: 126 ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALP 185
+ N++ + PGA L L++LDLS+N + PW+ + + AL L ++HN + +LP
Sbjct: 83 --AHNEVRTVEPGALA-VLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
Query: 186 PGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNCELLWL 245
A L L L + +NRL TLAP +A A L NP HC C L+WL
Sbjct: 140 RDALGALPDLRSLRINNNRLRTLAPGTF-------DALSALSHLQLYHNPFHCGCGLVWL 192
Query: 246 R------RLARPD-DLETCASPPGLAGRYFW-------AVPEGEFSCEPPLIARHTQRLW 291
+ R++ P+ D CASPP L G + A P S EPPL A T
Sbjct: 193 QAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAEPPLEAPGTP--- 249
Query: 292 VLEGQRATLRCRALGDPAPTMHW----------------VGPDDRLVGN----------- 324
+ G L C A G P P + W G DD +
Sbjct: 250 LRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLL 309
Query: 325 -------------------SSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVE 365
+ R A NG+L + + A +AG YTC A N G + +
Sbjct: 310 TQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIR 369
Query: 366 LRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEG--TLESEP 407
+ V A ++ GG P + ++ A+G G L S+P
Sbjct: 370 VAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKP 413
>gi|193083136 leucine-rich repeat, immunoglobulin-like and
transmembrane domains 3 [Homo sapiens]
Length = 634
Score = 113 bits (283), Expect = 5e-25
Identities = 89/271 (32%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 120 VNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHN 179
V LQ+L ++ N + I P +F + L+ L +L L N+L PWA + MP L TL+L +N
Sbjct: 36 VELQYLWVTYNSVASIDPSSFYN-LKQLHELRLDGNSLAAFPWASLLDMPLLRTLDLHNN 94
Query: 180 LIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFS-------RGRDAEASPAPLVLSFS 232
I ++P A L L+ LDL+SNRL TL PD L S + SP+ ++L
Sbjct: 95 KITSVPNEALRYLKNLAYLDLSSNRLTTLPPDFLESWTHLVSTPSGVLDLSPSRIILGLQ 154
Query: 233 GNPLHCNC---ELLWLRRLARP-----DDLETCASPPGLAGRYFWAVPEGEFSCEPPLIA 284
NP C+C +++ L ++ P D L TC+ P L G F E E +P ++
Sbjct: 155 DNPWFCDCHISKMIELSKVVDPAIVLLDPLMTCSEPERLTGILFQRA-ELEHCLKPSVMT 213
Query: 285 RHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGT----LEIGV 340
T+ + L G LRC A G P P + W D V + + G + +
Sbjct: 214 SATKIMSAL-GSNVLLRCDATGFPTPQITWTRSDSSPVNYTVIQESPEEGVRWSIMSLTG 272
Query: 341 TGAGDAGGYTCIATNPAGEATARVELRVLAL 371
+ DAG Y C A N AG + A V + VL +
Sbjct: 273 ISSKDAGDYKCKAKNLAGMSEAVVTVTVLGI 303
>gi|41582239 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 113 bits (283), Expect = 5e-25
Identities = 104/337 (30%), Positives = 140/337 (41%), Gaps = 59/337 (17%)
Query: 91 AFGDLESL--------RSLHLDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIAPGAFDD 142
A+ DLES+ +L L NRL L G+ R LQ L L+ N++ +A GA
Sbjct: 37 AYRDLESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALAS 96
Query: 143 FLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTS 202
L L+ LDLS+N + W+ + + AL L +D N + +P AF L L L L
Sbjct: 97 -LSHLKSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNH 155
Query: 203 NRLATLAPDPLFSRGRDAEASPAPLV----LSFSGNPLHCNCELLWLRRLA-------RP 251
NRL TL AE + PL L + NP C C ++WL+ A
Sbjct: 156 NRLHTL-----------AEGTFTPLTALSHLQINENPFDCTCGIVWLKTWALTTAVSIPE 204
Query: 252 DDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQ----RLWVLEGQRATLRCRALGD 307
D C SP L G +P C P + Q + G L C G
Sbjct: 205 QDNIACTSPHVLKGTPLSRLP--PLPCSAPSVQLSYQPSQDGAELRPGFVLALHCDVDGQ 262
Query: 308 PAPTMHW---------------VGPDDR------LVGNSSRARAFPNGTLEIGVTGAGDA 346
PAP +HW VG D R + + R +AF NG+L I G +
Sbjct: 263 PAPQLHWHIQIPSGIVEITSPNVGTDGRALPGTPVASSQPRFQAFANGSLLIPDFGKLEE 322
Query: 347 GGYTCIATNPAGEATARVELRVLALPHGGNSSAEGGR 383
G Y+C+ATN G A + V++ LA P G G R
Sbjct: 323 GTYSCLATNELGSAESSVDV-ALATPGEGGEDTLGRR 358
>gi|5031809 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 113 bits (283), Expect = 5e-25
Identities = 104/337 (30%), Positives = 140/337 (41%), Gaps = 59/337 (17%)
Query: 91 AFGDLESL--------RSLHLDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIAPGAFDD 142
A+ DLES+ +L L NRL L G+ R LQ L L+ N++ +A GA
Sbjct: 37 AYRDLESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALAS 96
Query: 143 FLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTS 202
L L+ LDLS+N + W+ + + AL L +D N + +P AF L L L L
Sbjct: 97 -LSHLKSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNH 155
Query: 203 NRLATLAPDPLFSRGRDAEASPAPLV----LSFSGNPLHCNCELLWLRRLA-------RP 251
NRL TL AE + PL L + NP C C ++WL+ A
Sbjct: 156 NRLHTL-----------AEGTFTPLTALSHLQINENPFDCTCGIVWLKTWALTTAVSIPE 204
Query: 252 DDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQ----RLWVLEGQRATLRCRALGD 307
D C SP L G +P C P + Q + G L C G
Sbjct: 205 QDNIACTSPHVLKGTPLSRLP--PLPCSAPSVQLSYQPSQDGAELRPGFVLALHCDVDGQ 262
Query: 308 PAPTMHW---------------VGPDDR------LVGNSSRARAFPNGTLEIGVTGAGDA 346
PAP +HW VG D R + + R +AF NG+L I G +
Sbjct: 263 PAPQLHWHIQIPSGIVEITSPNVGTDGRALPGTPVASSQPRFQAFANGSLLIPDFGKLEE 322
Query: 347 GGYTCIATNPAGEATARVELRVLALPHGGNSSAEGGR 383
G Y+C+ATN G A + V++ LA P G G R
Sbjct: 323 GTYSCLATNELGSAESSVDV-ALATPGEGGEDTLGRR 358
>gi|62988340 leucine rich repeat containing 22 [Homo sapiens]
Length = 550
Score = 113 bits (282), Expect = 6e-25
Identities = 94/314 (29%), Positives = 138/314 (43%), Gaps = 36/314 (11%)
Query: 96 ESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYN 155
E + + ++ + L E+ GS L++L L+ N + I GA + L L +L L N
Sbjct: 55 EEFKQVRIENSPLFEMPQGSFINMSTLEYLWLNFNNISVIHLGALEH-LPELRELRLEGN 113
Query: 156 NLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPD---- 211
L VPW A P L L+L N IDALP A L L+ LDL+SNRL ++
Sbjct: 114 KLCSVPWTAFRATPLLRVLDLKRNKIDALPELALQFLVSLTYLDLSSNRLTVVSKSVFLN 173
Query: 212 -PLFSRGRDAEASP---APLVLSFSGNPLHCNCELLWLRRLARPDDLET--------CAS 259
P + + R + + LV++ NP C+C L L + + L C
Sbjct: 174 WPAYQKCRQPDCGAEILSSLVVALHDNPWVCDCRLRGLVQFVKSITLPVILVNSYLICQG 233
Query: 260 PPGLAGRYFWAVPEGEFS-CEPPLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGP- 317
P AG+ F E E S C P I+ + + + GQ TLRC A P+P++ W P
Sbjct: 234 PLSKAGQLF---HETELSACMKPQISTPSANITIRAGQNVTLRCLAQASPSPSIAWTYPL 290
Query: 318 ---DDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVELRV------ 368
+ V SS L I D+G YTC+A+N G++ + L V
Sbjct: 291 SMWREFDVLTSSTGEDTALSELAIPAAHLVDSGNYTCMASNSIGKSNLVISLHVQPAQAL 350
Query: 369 -----LALPHGGNS 377
L++P GN+
Sbjct: 351 HAPDSLSIPSEGNA 364
>gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 112 bits (279), Expect = 1e-24
Identities = 113/441 (25%), Positives = 186/441 (42%), Gaps = 59/441 (13%)
Query: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
L + +N I + +F+ + L L ++ +T I A LE+L S+ NRL+++
Sbjct: 193 LMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVP 252
Query: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQ---VPWAGIGAMP 169
+L+ VNL+ L L+ N + RI G F + L E L NN+ + + + +P
Sbjct: 253 HVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKE---LGINNMPELISIDSLAVDNLP 309
Query: 170 ALHTLNLDHN-LIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLV 228
L + +N + + P AF +L +L L L SN L+ L + E+ P
Sbjct: 310 DLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTI-------ESLPNLKE 362
Query: 229 LSFSGNPLHCNCELLWLR------RLARPDDLETCASPPGLAGRYFWAVP-EGEFSCEPP 281
+S NP+ C+C + W+ R PD L C PP G+ V P
Sbjct: 363 ISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSL-FCVDPPEFQGQNVRQVHFRDMMEICLP 421
Query: 282 LIARHT--QRLWVLEGQRATLRCRALGDPAPTMHWVGPD-DRLVGNSSRARAF--PNGTL 336
LIA + L V G + CRA +P P ++W+ P +L+ N+ + + GTL
Sbjct: 422 LIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTL 481
Query: 337 EIGVTGAGDAGGYTCIATNPAGEATARVELRVLALPHGGNSSAEGGRPGPSDIAASARTA 396
+I + G YTCIATN G V ++V +G P
Sbjct: 482 DINGVTPKEGGLYTCIATNLVGADLKSVMIKV-----------DGSFP------------ 518
Query: 397 AEGEGTLESEPAVQVTEVTATSGLVSWGPGR---PADPVWMFQIQYNSSEDETLIYRIVP 453
+ G+L +++ ++ A S LVSW + W ++ +S +P
Sbjct: 519 QDNNGSLN----IKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSAR--IP 572
Query: 454 ASSHHFLLKHLVPGADYDLCL 474
+ + L HL P +Y +C+
Sbjct: 573 SDVKVYNLTHLNPSTEYKICI 593
Score = 58.5 bits (140), Expect = 2e-08
Identities = 62/208 (29%), Positives = 91/208 (43%), Gaps = 15/208 (7%)
Query: 17 CPLPCVCQ--------NLSESLSTL-CAHRGLLFVPPNVDRRTVELRLADNFIQALG-PP 66
CP C C+ ++ ST+ C GLL P + T L L N I +
Sbjct: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
Query: 67 DFR-NMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
DF N+TGL LS+N ++ + + L S++L+ N+L EL L NLQ L
Sbjct: 89 DFPVNLTGL---DLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQEL 145
Query: 126 ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALP 185
++ N L I+PGAF L +L L L+ N L+ + A+P L L + N I +
Sbjct: 146 YINHNLLSTISPGAFIG-LHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
Query: 186 PGAFAQLGQLSRLDLTSNRLATLAPDPL 213
F L L L + L + + L
Sbjct: 205 DMNFKPLINLRSLVIAGINLTEIPDNAL 232
>gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 112 bits (279), Expect = 1e-24
Identities = 113/441 (25%), Positives = 186/441 (42%), Gaps = 59/441 (13%)
Query: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
L + +N I + +F+ + L L ++ +T I A LE+L S+ NRL+++
Sbjct: 193 LMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVP 252
Query: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQ---VPWAGIGAMP 169
+L+ VNL+ L L+ N + RI G F + L E L NN+ + + + +P
Sbjct: 253 HVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKE---LGINNMPELISIDSLAVDNLP 309
Query: 170 ALHTLNLDHN-LIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLV 228
L + +N + + P AF +L +L L L SN L+ L + E+ P
Sbjct: 310 DLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTI-------ESLPNLKE 362
Query: 229 LSFSGNPLHCNCELLWLR------RLARPDDLETCASPPGLAGRYFWAVP-EGEFSCEPP 281
+S NP+ C+C + W+ R PD L C PP G+ V P
Sbjct: 363 ISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSL-FCVDPPEFQGQNVRQVHFRDMMEICLP 421
Query: 282 LIARHT--QRLWVLEGQRATLRCRALGDPAPTMHWVGPD-DRLVGNSSRARAF--PNGTL 336
LIA + L V G + CRA +P P ++W+ P +L+ N+ + + GTL
Sbjct: 422 LIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTL 481
Query: 337 EIGVTGAGDAGGYTCIATNPAGEATARVELRVLALPHGGNSSAEGGRPGPSDIAASARTA 396
+I + G YTCIATN G V ++V +G P
Sbjct: 482 DINGVTPKEGGLYTCIATNLVGADLKSVMIKV-----------DGSFP------------ 518
Query: 397 AEGEGTLESEPAVQVTEVTATSGLVSWGPGR---PADPVWMFQIQYNSSEDETLIYRIVP 453
+ G+L +++ ++ A S LVSW + W ++ +S +P
Sbjct: 519 QDNNGSLN----IKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSAR--IP 572
Query: 454 ASSHHFLLKHLVPGADYDLCL 474
+ + L HL P +Y +C+
Sbjct: 573 SDVKVYNLTHLNPSTEYKICI 593
Score = 58.5 bits (140), Expect = 2e-08
Identities = 62/208 (29%), Positives = 91/208 (43%), Gaps = 15/208 (7%)
Query: 17 CPLPCVCQ--------NLSESLSTL-CAHRGLLFVPPNVDRRTVELRLADNFIQALG-PP 66
CP C C+ ++ ST+ C GLL P + T L L N I +
Sbjct: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
Query: 67 DFR-NMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
DF N+TGL LS+N ++ + + L S++L+ N+L EL L NLQ L
Sbjct: 89 DFPVNLTGL---DLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQEL 145
Query: 126 ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALP 185
++ N L I+PGAF L +L L L+ N L+ + A+P L L + N I +
Sbjct: 146 YINHNLLSTISPGAFIG-LHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
Query: 186 PGAFAQLGQLSRLDLTSNRLATLAPDPL 213
F L L L + L + + L
Sbjct: 205 DMNFKPLINLRSLVIAGINLTEIPDNAL 232
>gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 112 bits (279), Expect = 1e-24
Identities = 113/441 (25%), Positives = 186/441 (42%), Gaps = 59/441 (13%)
Query: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
L + +N I + +F+ + L L ++ +T I A LE+L S+ NRL+++
Sbjct: 193 LMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVP 252
Query: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQ---VPWAGIGAMP 169
+L+ VNL+ L L+ N + RI G F + L E L NN+ + + + +P
Sbjct: 253 HVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKE---LGINNMPELISIDSLAVDNLP 309
Query: 170 ALHTLNLDHN-LIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLV 228
L + +N + + P AF +L +L L L SN L+ L + E+ P
Sbjct: 310 DLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTI-------ESLPNLKE 362
Query: 229 LSFSGNPLHCNCELLWLR------RLARPDDLETCASPPGLAGRYFWAVP-EGEFSCEPP 281
+S NP+ C+C + W+ R PD L C PP G+ V P
Sbjct: 363 ISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSL-FCVDPPEFQGQNVRQVHFRDMMEICLP 421
Query: 282 LIARHT--QRLWVLEGQRATLRCRALGDPAPTMHWVGPD-DRLVGNSSRARAF--PNGTL 336
LIA + L V G + CRA +P P ++W+ P +L+ N+ + + GTL
Sbjct: 422 LIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTL 481
Query: 337 EIGVTGAGDAGGYTCIATNPAGEATARVELRVLALPHGGNSSAEGGRPGPSDIAASARTA 396
+I + G YTCIATN G V ++V +G P
Sbjct: 482 DINGVTPKEGGLYTCIATNLVGADLKSVMIKV-----------DGSFP------------ 518
Query: 397 AEGEGTLESEPAVQVTEVTATSGLVSWGPGR---PADPVWMFQIQYNSSEDETLIYRIVP 453
+ G+L +++ ++ A S LVSW + W ++ +S +P
Sbjct: 519 QDNNGSLN----IKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSAR--IP 572
Query: 454 ASSHHFLLKHLVPGADYDLCL 474
+ + L HL P +Y +C+
Sbjct: 573 SDVKVYNLTHLNPSTEYKICI 593
Score = 58.5 bits (140), Expect = 2e-08
Identities = 62/208 (29%), Positives = 91/208 (43%), Gaps = 15/208 (7%)
Query: 17 CPLPCVCQ--------NLSESLSTL-CAHRGLLFVPPNVDRRTVELRLADNFIQALG-PP 66
CP C C+ ++ ST+ C GLL P + T L L N I +
Sbjct: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
Query: 67 DFR-NMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
DF N+TGL LS+N ++ + + L S++L+ N+L EL L NLQ L
Sbjct: 89 DFPVNLTGL---DLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQEL 145
Query: 126 ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALP 185
++ N L I+PGAF L +L L L+ N L+ + A+P L L + N I +
Sbjct: 146 YINHNLLSTISPGAFIG-LHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
Query: 186 PGAFAQLGQLSRLDLTSNRLATLAPDPL 213
F L L L + L + + L
Sbjct: 205 DMNFKPLINLRSLVIAGINLTEIPDNAL 232
>gi|50263044 leucine-rich repeat neuronal 6A [Homo sapiens]
Length = 620
Score = 107 bits (268), Expect = 3e-23
Identities = 132/532 (24%), Positives = 186/532 (34%), Gaps = 149/532 (28%)
Query: 4 PLLLLLLAS----GAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRT--------- 50
P+LLL+L S A CP C C ++ + LC + + VP + T
Sbjct: 25 PILLLVLGSVLSGSATGCPPRCECS--AQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNR 82
Query: 51 ---------------VELRLADNFIQALGPPDFRNM---------------------TGL 74
EL L +N + A+ P F N+ TGL
Sbjct: 83 IKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGL 142
Query: 75 VDLT---------------------------LSRNAITRIGARAFGDLESLRSLHLDGNR 107
+LT + N + I RAF L SL L L+
Sbjct: 143 SNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCN 202
Query: 108 LVELGTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLE---------------------- 145
L + T +L L L L + I +F
Sbjct: 203 LTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYG 262
Query: 146 -SLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALP------------------- 185
+L L +++ NL VP+ + + L LNL +N I +
Sbjct: 263 LNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQ 322
Query: 186 -----PGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNC 240
P AF L L L+++ N+L TL S G L NPL C+C
Sbjct: 323 LAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLE-------TLILDSNPLACDC 375
Query: 241 ELLWLRR----LARPDDLETCASPPGLAGRYFWAVPE----GEFSCEPPLIA-RHTQRLW 291
LLW+ R L TCA+P + G+ F P+ F+C I R Q+++
Sbjct: 376 RLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFTCRRARIRDRKAQQVF 435
Query: 292 VLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRAR--AFPNGTLEIGVTGAGDAGGY 349
V EG CRA GDP P + W+ P LV S R FP+GTLE+ D G Y
Sbjct: 436 VDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDGTLEVRYAQVQDNGTY 495
Query: 350 TCIATNPAGEATARVELRVLAL----PHGGNSSAE--GGRPGPSDIAASART 395
CIA N G + L V + PH N + +PG + ++ T
Sbjct: 496 LCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGEANSTRAT 547
>gi|153791330 leucine rich repeat neuronal 1 [Homo sapiens]
Length = 716
Score = 105 bits (261), Expect = 2e-22
Identities = 133/510 (26%), Positives = 206/510 (40%), Gaps = 125/510 (24%)
Query: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRL---- 108
L L +N I + ++++ L +L ++ N I+ I A AF L++L LHL+ N+L
Sbjct: 124 LHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVID 183
Query: 109 ------------VELGTGSLRGPV--------NLQHLILSGNQLGRIAPGAFDDFLESLE 148
+ +G + G + NL+ L+L+G L I PG L+SLE
Sbjct: 184 SRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDI-PGNALVGLDSLE 242
Query: 149 DLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQ----------------- 191
L N L +VP + +P L L+L+ N I + G F
Sbjct: 243 SLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVS 302
Query: 192 --------LGQLSRLDLTSN-------RLATLAPDPLFSR-----------GRDAEASPA 225
L +L++L+ T+N RLA + L S + E+ P
Sbjct: 303 VDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPN 362
Query: 226 PLVLSFSGNPLHCNCELLWLR------RLARPDDLETCASPPGLAGRYFWAVPEGEFSCE 279
+S NPL C+C + W+ R P + CA PP G V + S +
Sbjct: 363 LREISIHSNPLRCDCVIHWINSNKTNIRFMEPLSM-FCAMPPEYKGHQVKEVLIQDSSEQ 421
Query: 280 P-PLIARHT--QRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGN-------SSRAR 329
P+I+ + RL V G L CRA+ +P P ++WV P +GN S + +
Sbjct: 422 CLPMISHDSFPNRLNVDIGTTVFLDCRAMAEPEPEIYWVTP----IGNKITVETLSDKYK 477
Query: 330 AFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVELRVLALPHGGNSSAEGGRPGPSDI 389
GTLEI D+G YTC+A N G T RV + G
Sbjct: 478 LSSEGTLEISNIQIEDSGRYTCVAQNVQGADT-----RVATIKVNG-------------- 518
Query: 390 AASARTAAEGEGTLESEPAVQVTEVTATSGLVSWGPGRPADPVWMFQIQYNSS----EDE 445
T +G L+ + V + + S LVSW + V ++++S+ ++
Sbjct: 519 -----TLLDGTQVLK----IYVKQTESHSILVSW---KVNSNVMTSNLKWSSATMKIDNP 566
Query: 446 TLIYRI-VPASSHHFLLKHLVPGADYDLCL 474
+ Y VP H + L HL P DY++CL
Sbjct: 567 HITYTARVPVDVHEYNLTHLQPSTDYEVCL 596
Score = 63.5 bits (153), Expect = 6e-10
Identities = 64/229 (27%), Positives = 97/229 (42%), Gaps = 18/229 (7%)
Query: 17 CPLPCVCQ---------NLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPD 67
CP CVC+ E+ + C L +P N+ T L L N I A +
Sbjct: 32 CPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSNLSSDTQVLLLQSNNI-AKTVDE 90
Query: 68 FRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLIL 127
+ + L +L S+N T I +L L +LHL+ N++ E+ L+ NLQ L +
Sbjct: 91 LQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYI 150
Query: 128 SGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPG 187
+ NQ+ I+ AF L++L L L+ N L+ + + P L L + N + +
Sbjct: 151 NHNQISTISAHAFAG-LKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDM 209
Query: 188 AFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPL 236
F L L L L L + + L G D+ S LSF N L
Sbjct: 210 NFKPLANLRSLVLAGMYLTDIPGNALV--GLDSLES-----LSFYDNKL 251
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,492,305
Number of Sequences: 37866
Number of extensions: 1617672
Number of successful extensions: 12938
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 345
Number of HSP's successfully gapped in prelim test: 273
Number of HSP's that attempted gapping in prelim test: 8625
Number of HSP's gapped (non-prelim): 2610
length of query: 635
length of database: 18,247,518
effective HSP length: 109
effective length of query: 526
effective length of database: 14,120,124
effective search space: 7427185224
effective search space used: 7427185224
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.