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Search of human proteins with 26667211
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26667211 calcium/calmodulin-dependent protein kinase II
gamma isoform 6 [Homo sapiens]
(504 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 1034 0.0
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 1025 0.0
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 1008 0.0
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 1004 0.0
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 1001 0.0
gi|26051208 calcium/calmodulin-dependent protein kinase II beta ... 927 0.0
gi|26051210 calcium/calmodulin-dependent protein kinase II beta ... 921 0.0
gi|26051206 calcium/calmodulin-dependent protein kinase II beta ... 912 0.0
gi|26051212 calcium/calmodulin-dependent protein kinase II beta ... 904 0.0
gi|26051216 calcium/calmodulin-dependent protein kinase II beta ... 891 0.0
gi|212549753 calcium/calmodulin-dependent protein kinase II delt... 885 0.0
gi|212549756 calcium/calmodulin-dependent protein kinase II delt... 867 0.0
gi|26667183 calcium/calmodulin-dependent protein kinase II delta... 867 0.0
gi|26667186 calcium/calmodulin-dependent protein kinase II delta... 867 0.0
gi|26667180 calcium/calmodulin-dependent protein kinase II delta... 867 0.0
gi|26667189 calcium/calmodulin-dependent protein kinase II delta... 866 0.0
gi|26051214 calcium/calmodulin-dependent protein kinase II beta ... 836 0.0
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha... 831 0.0
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha... 828 0.0
gi|26051218 calcium/calmodulin-dependent protein kinase II beta ... 803 0.0
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 647 0.0
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 275 5e-74
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 275 5e-74
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 275 5e-74
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 243 2e-64
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 236 5e-62
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 236 5e-62
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 233 4e-61
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca... 226 5e-59
gi|209364619 pregnancy upregulated non-ubiquitously expressed Ca... 226 5e-59
>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
isoform 6 [Homo sapiens]
Length = 504
Score = 1034 bits (2674), Expect = 0.0
Identities = 504/504 (100%), Positives = 504/504 (100%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF
Sbjct: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV
Sbjct: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
Query: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
WHRRDGKWLNVHYHCSGAPAAPLQ
Sbjct: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
isoform 3 [Homo sapiens]
Length = 518
Score = 1025 bits (2649), Expect = 0.0
Identities = 504/518 (97%), Positives = 504/518 (97%), Gaps = 14/518 (2%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSL--------------EPQTTVV 346
KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSL EPQTTVV
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360
Query: 347 HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF 406
HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF
Sbjct: 361 HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF 420
Query: 407 EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 466
EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG
Sbjct: 421 EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 480
Query: 467 QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 504
QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ
Sbjct: 481 QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 518
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 1008 bits (2607), Expect = 0.0
Identities = 495/504 (98%), Positives = 495/504 (98%), Gaps = 9/504 (1%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
KGAILTTMLVSRNFSAAKSLLNKKSDGGVK EPQTTVVHNATDGIKGSTESC
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVK---------EPQTTVVHNATDGIKGSTESC 351
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF
Sbjct: 352 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 411
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV
Sbjct: 412 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 471
Query: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
WHRRDGKWLNVHYHCSGAPAAPLQ
Sbjct: 472 WHRRDGKWLNVHYHCSGAPAAPLQ 495
>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
isoform 1 [Homo sapiens]
Length = 556
Score = 1004 bits (2597), Expect = 0.0
Identities = 503/556 (90%), Positives = 504/556 (90%), Gaps = 52/556 (9%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSL--------------EPQTTVV 346
KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSL EPQTTVV
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360
Query: 347 HNATDGIKGSTESCNTTTEDEDLK------------------------------------ 370
HNATDGIKGSTESCNTTTEDEDLK
Sbjct: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420
Query: 371 --VRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 428
+RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL
Sbjct: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480
Query: 429 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 488
LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW
Sbjct: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540
Query: 489 LNVHYHCSGAPAAPLQ 504
LNVHYHCSGAPAAPLQ
Sbjct: 541 LNVHYHCSGAPAAPLQ 556
>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
isoform 2 [Homo sapiens]
Length = 527
Score = 1001 bits (2587), Expect = 0.0
Identities = 496/527 (94%), Positives = 501/527 (95%), Gaps = 23/527 (4%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLVSRNFS---------------------AAKSLLNKKSDGGVKPQ--SNNKN 337
KGAILTTMLVSRNFS AAKSLLNKKSDGGVK + S++ +
Sbjct: 301 KGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVH 360
Query: 338 SLEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTK 397
+EPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTK
Sbjct: 361 LMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTK 420
Query: 398 ICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAY 457
ICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAY
Sbjct: 421 ICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAY 480
Query: 458 IRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 504
IRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ
Sbjct: 481 IRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 527
>gi|26051208 calcium/calmodulin-dependent protein kinase II beta
isoform 3 [Homo sapiens]
Length = 518
Score = 927 bits (2397), Expect = 0.0
Identities = 456/519 (87%), Positives = 478/519 (92%), Gaps = 16/519 (3%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNN-KNS--------------LEPQTTV 345
KGAILTTML +RNFSAAKSLLNKK+D GVKPQ+N+ KNS LEPQTTV
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKAD-GVKPQTNSTKNSAAATSPKGTLPPAALEPQTTV 359
Query: 346 VHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTS 405
+HN DGIK S++S NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTS
Sbjct: 360 IHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTS 419
Query: 406 FEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID 465
FEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID
Sbjct: 420 FEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID 479
Query: 466 GQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 504
GQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 480 GQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 518
>gi|26051210 calcium/calmodulin-dependent protein kinase II beta
isoform 4 [Homo sapiens]
Length = 517
Score = 921 bits (2381), Expect = 0.0
Identities = 455/519 (87%), Positives = 477/519 (91%), Gaps = 17/519 (3%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNN-KNS--------------LEPQTTV 345
KGAILTTML +RNFS AKSLLNKK+D GVKPQ+N+ KNS LEPQTTV
Sbjct: 301 KGAILTTMLATRNFS-AKSLLNKKAD-GVKPQTNSTKNSAAATSPKGTLPPAALEPQTTV 358
Query: 346 VHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTS 405
+HN DGIK S++S NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTS
Sbjct: 359 IHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTS 418
Query: 406 FEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID 465
FEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID
Sbjct: 419 FEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID 478
Query: 466 GQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 504
GQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 479 GQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
>gi|26051206 calcium/calmodulin-dependent protein kinase II beta
isoform 2 [Homo sapiens]
Length = 542
Score = 912 bits (2358), Expect = 0.0
Identities = 455/543 (83%), Positives = 477/543 (87%), Gaps = 40/543 (7%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDGGVKPQSNN- 335
KGAILTTML +RNFS AKSLLNKK+D GVKPQ+N+
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKAD-GVKPQTNST 359
Query: 336 KNS--------------LEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITE 381
KNS LEPQTTV+HN DGIK S++S NTT EDED K RKQEIIK TE
Sbjct: 360 KNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTE 419
Query: 382 QLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTIL 441
QLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTIL
Sbjct: 420 QLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTIL 479
Query: 442 NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAA 501
NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP A
Sbjct: 480 NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVA 539
Query: 502 PLQ 504
PLQ
Sbjct: 540 PLQ 542
>gi|26051212 calcium/calmodulin-dependent protein kinase II beta
isoform 5 [Homo sapiens]
Length = 503
Score = 904 bits (2336), Expect = 0.0
Identities = 441/504 (87%), Positives = 464/504 (92%), Gaps = 1/504 (0%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
KGAILTTML +RNFSAAKSLLNKK+D GVKPQ+N+ + T+ S++S
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKAD-GVKPQTNSTKNSAAATSPKGTLPPAALESSDSA 359
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDF
Sbjct: 360 NTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDF 419
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
H+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV
Sbjct: 420 HRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 479
Query: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
WHRRDGKW NVH+HCSGAP APLQ
Sbjct: 480 WHRRDGKWQNVHFHCSGAPVAPLQ 503
>gi|26051216 calcium/calmodulin-dependent protein kinase II beta
isoform 7 [Homo sapiens]
Length = 479
Score = 891 bits (2302), Expect = 0.0
Identities = 436/504 (86%), Positives = 456/504 (90%), Gaps = 25/504 (4%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
KGAILTTML +RNFSAAKSLLNKK+ DG+K S++S
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKA-------------------------DGVKESSDSA 335
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDF
Sbjct: 336 NTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDF 395
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
H+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV
Sbjct: 396 HRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 455
Query: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
WHRRDGKW NVH+HCSGAP APLQ
Sbjct: 456 WHRRDGKWQNVHFHCSGAPVAPLQ 479
>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
isoform 5 [Homo sapiens]
Length = 492
Score = 885 bits (2287), Expect = 0.0
Identities = 432/504 (85%), Positives = 463/504 (91%), Gaps = 12/504 (2%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
KGAILTTML +RNFSAAKSLL K GVK EPQTTV+HN DG K STES
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPD--GVK---------EPQTTVIHN-PDGNKESTESS 348
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDF
Sbjct: 349 NTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDF 408
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
H+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRV
Sbjct: 409 HRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRV 468
Query: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
WHRRDGKW NVH+H SG+P P++
Sbjct: 469 WHRRDGKWQNVHFHRSGSPTVPIK 492
>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
isoform 4 [Homo sapiens]
Length = 489
Score = 867 bits (2239), Expect = 0.0
Identities = 423/504 (83%), Positives = 457/504 (90%), Gaps = 15/504 (2%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
KGAILTTML +RNFSAAKSLL KK DG K +S++ + STES
Sbjct: 301 KGAILTTMLATRNFSAAKSLL-KKPDGVKKRKSSSSVQM--------------MESTESS 345
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDF
Sbjct: 346 NTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDF 405
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
H+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRV
Sbjct: 406 HRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRV 465
Query: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
WHRRDGKW NVH+H SG+P P++
Sbjct: 466 WHRRDGKWQNVHFHRSGSPTVPIK 489
>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 867 bits (2239), Expect = 0.0
Identities = 421/504 (83%), Positives = 452/504 (89%), Gaps = 26/504 (5%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
KGAILTTML +RNFSAAKSLL K DG+K STES
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK--------------------------PDGVKESTESS 334
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDF
Sbjct: 335 NTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDF 394
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
H+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRV
Sbjct: 395 HRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRV 454
Query: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
WHRRDGKW NVH+H SG+P P++
Sbjct: 455 WHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 867 bits (2239), Expect = 0.0
Identities = 421/504 (83%), Positives = 452/504 (89%), Gaps = 26/504 (5%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
KGAILTTML +RNFSAAKSLL K DG+K STES
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK--------------------------PDGVKESTESS 334
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDF
Sbjct: 335 NTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDF 394
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
H+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRV
Sbjct: 395 HRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRV 454
Query: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
WHRRDGKW NVH+H SG+P P++
Sbjct: 455 WHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
isoform 3 [Homo sapiens]
Length = 499
Score = 867 bits (2239), Expect = 0.0
Identities = 421/504 (83%), Positives = 452/504 (89%), Gaps = 26/504 (5%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
KGAILTTML +RNFSAAKSLL K DG+K STES
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK--------------------------PDGVKESTESS 334
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDF
Sbjct: 335 NTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDF 394
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
H+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRV
Sbjct: 395 HRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRV 454
Query: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
WHRRDGKW NVH+H SG+P P++
Sbjct: 455 WHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
isoform 2 [Homo sapiens]
Length = 478
Score = 866 bits (2238), Expect = 0.0
Identities = 421/503 (83%), Positives = 451/503 (89%), Gaps = 26/503 (5%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
KGAILTTML +RNFSAAKSLL K DG+K STES
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK--------------------------PDGVKESTESS 334
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDF
Sbjct: 335 NTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDF 394
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
H+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRV
Sbjct: 395 HRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRV 454
Query: 481 WHRRDGKWLNVHYHCSGAPAAPL 503
WHRRDGKW NVH+H SG+P P+
Sbjct: 455 WHRRDGKWQNVHFHRSGSPTVPI 477
>gi|26051214 calcium/calmodulin-dependent protein kinase II beta
isoform 6 [Homo sapiens]
Length = 492
Score = 836 bits (2160), Expect = 0.0
Identities = 423/528 (80%), Positives = 442/528 (83%), Gaps = 60/528 (11%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDGGVKPQSNNK 336
KGAILTTML +RNFS AKSLLNKK+D GVK
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKAD-GVK------ 353
Query: 337 NSLEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYT 396
EPQTTV+HN DGIK S++S NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY
Sbjct: 354 ---EPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYA 410
Query: 397 KICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIA 456
FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIA
Sbjct: 411 --------------------------FYFENLLAKNSKPIHTTILNPHVHVIGEDAACIA 444
Query: 457 YIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 504
YIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 445 YIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 492
>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
isoform 1 [Homo sapiens]
Length = 489
Score = 831 bits (2147), Expect = 0.0
Identities = 403/497 (81%), Positives = 445/497 (89%), Gaps = 14/497 (2%)
Query: 4 TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63
T TCTRFT++YQLFEELGKGAFSVVRRCVK + QEYAAKIINTKKLSARDHQKLEREAR
Sbjct: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
Query: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123
ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
Query: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183
V H HQ +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP
Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
Query: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
Query: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303
EAK+LIN+MLTINP+KRITA +ALKHPW+ RSTVAS MHRQETV+CL+KFNARRKLKGA
Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
Query: 304 ILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESCNTT 363
ILTTML +RNFS KS NKKSDG K +S++ L S+ES NTT
Sbjct: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQL--------------MESSESTNTT 348
Query: 364 TEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKF 423
EDED KVRKQEIIK+TEQLIEAI+NGDFE+YTK+CDPG+T+FEPEALGNLVEG+DFH+F
Sbjct: 349 IEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRF 408
Query: 424 YFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHR 483
YFENL S+NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHR
Sbjct: 409 YFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHR 468
Query: 484 RDGKWLNVHYHCSGAPA 500
RDGKW VH+H SGAP+
Sbjct: 469 RDGKWQIVHFHRSGAPS 485
>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
isoform 2 [Homo sapiens]
Length = 478
Score = 828 bits (2139), Expect = 0.0
Identities = 401/497 (80%), Positives = 441/497 (88%), Gaps = 25/497 (5%)
Query: 4 TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63
T TCTRFT++YQLFEELGKGAFSVVRRCVK + QEYAAKIINTKKLSARDHQKLEREAR
Sbjct: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
Query: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123
ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
Query: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183
V H HQ +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP
Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
Query: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
Query: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303
EAK+LIN+MLTINP+KRITA +ALKHPW+ RSTVAS MHRQETV+CL+KFNARRKLKGA
Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
Query: 304 ILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESCNTT 363
ILTTML +RNFS KS NKKS DG+K S+ES NTT
Sbjct: 303 ILTTMLATRNFSGGKSGGNKKS-------------------------DGVKESSESTNTT 337
Query: 364 TEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKF 423
EDED KVRKQEIIK+TEQLIEAI+NGDFE+YTK+CDPG+T+FEPEALGNLVEG+DFH+F
Sbjct: 338 IEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRF 397
Query: 424 YFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHR 483
YFENL S+NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHR
Sbjct: 398 YFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHR 457
Query: 484 RDGKWLNVHYHCSGAPA 500
RDGKW VH+H SGAP+
Sbjct: 458 RDGKWQIVHFHRSGAPS 474
>gi|26051218 calcium/calmodulin-dependent protein kinase II beta
isoform 8 [Homo sapiens]
Length = 449
Score = 803 bits (2075), Expect = 0.0
Identities = 400/504 (79%), Positives = 418/504 (82%), Gaps = 55/504 (10%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KF
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKF------ 294
Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
NA +KG+
Sbjct: 295 -----------------------------------------------NARRKLKGAI--L 305
Query: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
T + RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDF
Sbjct: 306 TTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDF 365
Query: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
H+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV
Sbjct: 366 HRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 425
Query: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
WHRRDGKW NVH+HCSGAP APLQ
Sbjct: 426 WHRRDGKWQNVHFHCSGAPVAPLQ 449
>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
isoform 1 [Homo sapiens]
Length = 666
Score = 647 bits (1670), Expect = 0.0
Identities = 330/409 (80%), Positives = 348/409 (85%), Gaps = 40/409 (9%)
Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDGGVKPQSNN- 335
KGAILTTML +RNFS AKSLLNKK+D GVKPQ+N+
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKAD-GVKPQTNST 359
Query: 336 KNS--------------LEPQTTVVHNATDGIKGSTESCNTTTEDEDLK 370
KNS LEPQTTV+HN DGIK S++S NTT EDED K
Sbjct: 360 KNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAK 408
Score = 269 bits (688), Expect = 4e-72
Identities = 125/133 (93%), Positives = 129/133 (96%)
Query: 372 RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSK 431
RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+K
Sbjct: 534 RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAK 593
Query: 432 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNV 491
NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NV
Sbjct: 594 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNV 653
Query: 492 HYHCSGAPAAPLQ 504
H+HCSGAP APLQ
Sbjct: 654 HFHCSGAPVAPLQ 666
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 275 bits (704), Expect = 5e-74
Identities = 141/306 (46%), Positives = 205/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E +GKG FSVVRRC+ + + Q++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIHQILE 122
+LKHP+IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH + QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
++ + H ++I+HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV++++PYGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +AL HPW+ +R A +H ETVE LRKFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 275 bits (704), Expect = 5e-74
Identities = 141/306 (46%), Positives = 205/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E +GKG FSVVRRC+ + + Q++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIHQILE 122
+LKHP+IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH + QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
++ + H ++I+HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV++++PYGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +AL HPW+ +R A +H ETVE LRKFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 275 bits (704), Expect = 5e-74
Identities = 141/306 (46%), Positives = 205/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E +GKG FSVVRRC+ + + Q++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIHQILE 122
+LKHP+IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH + QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
++ + H ++I+HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV++++PYGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +AL HPW+ +R A +H ETVE LRKFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 243 bits (621), Expect = 2e-64
Identities = 145/386 (37%), Positives = 224/386 (58%), Gaps = 20/386 (5%)
Query: 11 TDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
+D +++ ELG+GA S+V RC +K + + YA K++ D + + E + L H
Sbjct: 43 SDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK----KTVDKKIVRTEIGVLLRLSH 98
Query: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130
PNI++L + LV +LVTGGELF+ IV + YYSE DA+ + QILE+V ++H++
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDP 190
IVHRDLKPENLL A+ A +K+ADFGL+ ++ Q GTPGY +PE+LR
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLS-KIVEHQVLMKTVCGTPGYCAPEILRGCA 217
Query: 191 YGKPVDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
YG VD+W+ G+I YILL G+ PF+DE DQ ++++I Y F SP WD V+ AK+L
Sbjct: 218 YGPEVDMWSVGIITYILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDL 276
Query: 249 INQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTM 308
+ +++ ++P KR+T QAL+HPWV ++ A+ +H + L++FNARRKLK A+ +
Sbjct: 277 VRKLIVLDPKKRLTTFQALQHPWVTGKA--ANFVHMDTAQKKLQEFNARRKLKAAVKAVV 334
Query: 309 LVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESCNTTTEDED 368
SR SA+ S G + Q ++K S +P + + + + +K E +
Sbjct: 335 ASSRLGSAS------SSHGSI--QESHKASRDP--SPIQDGNEDMKAIPEGEKIQGDGAQ 384
Query: 369 LKVRKQEIIKITEQLIEAINNGDFEA 394
V+ + + Q +E + D A
Sbjct: 385 AAVKGAQAELMKVQALEKVKGADINA 410
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 236 bits (601), Expect = 5e-62
Identities = 123/297 (41%), Positives = 183/297 (61%), Gaps = 3/297 (1%)
Query: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
++ E LG GAFS V +K + + +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
V L D YLV LV+GGELF+ IV + +Y+E DAS I Q+L++V ++H+ IV
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK 193
HRDLKPENLL S+ + + + ++DFGL+ +++G+ GTPGY++PEVL + PY K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 254 TINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLV 310
+P KR T +QA +HPW+ + + +H + + +RK A+ K + A T +V
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQ-IRKNFAKSKWRQAFNATAVV 316
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
2 [Homo sapiens]
Length = 385
Score = 236 bits (601), Expect = 5e-62
Identities = 123/297 (41%), Positives = 183/297 (61%), Gaps = 3/297 (1%)
Query: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
++ E LG GAFS V +K + + +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
V L D YLV LV+GGELF+ IV + +Y+E DAS I Q+L++V ++H+ IV
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK 193
HRDLKPENLL S+ + + + ++DFGL+ +++G+ GTPGY++PEVL + PY K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 254 TINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLV 310
+P KR T +QA +HPW+ + + +H + + +RK A+ K + A T +V
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQ-IRKNFAKSKWRQAFNATAVV 316
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 233 bits (593), Expect = 4e-61
Identities = 125/299 (41%), Positives = 179/299 (59%), Gaps = 3/299 (1%)
Query: 12 DDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
D Y + LG GAFS V K + + A K I + L ++ +E E + +KHP
Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS-MENEIAVLHKIKHP 76
Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131
NIV L D G YL+ LV+GGELF+ IV + +Y+E DAS I Q+L++V ++H
Sbjct: 77 NIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLG 136
Query: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY 191
IVHRDLKPENLL S + + + ++DFGL+ +++ GTPGY++PEVL + PY
Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLS-KMEDPGSVLSTACGTPGYVAPEVLAQKPY 195
Query: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
K VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRH 255
Query: 252 MLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLV 310
++ +P KR T +QAL+HPW+ + + +H Q E ++K A+ K K A T +V
Sbjct: 256 LMEKDPEKRFTCEQALQHPWIAGDTALDKNIH-QSVSEQIKKNFAKSKWKQAFNATAVV 313
>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform b [Homo sapiens]
Length = 360
Score = 226 bits (575), Expect = 5e-59
Identities = 119/260 (45%), Positives = 162/260 (62%), Gaps = 5/260 (1%)
Query: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Y++ E LG GAFS V ++ S A K I K L ++ +E E + R + HPNI
Sbjct: 32 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKE-ALVENEIAVLRRISHPNI 90
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
V L D YL +LVTGGELF+ I+ R Y+E DASH + Q+L +V+++H IV
Sbjct: 91 VALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIV 150
Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GTPGYLSPEVLRKDPYG 192
HRDLKPENLL A+ + + + ++DFGL+ G G A GTPGY++PE+L + PYG
Sbjct: 151 HRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNM---LGTACGTPGYVAPELLEQKPYG 207
Query: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
K VD+WA GVI YILL GYPPF+DE +L+ QI +Y+F SP WD ++ AK+ I +
Sbjct: 208 KAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHL 267
Query: 253 LTINPAKRITADQALKHPWV 272
L +P KR T QAL+H W+
Sbjct: 268 LERDPQKRFTCQQALRHLWI 287
>gi|209364619 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform a [Homo sapiens]
Length = 426
Score = 226 bits (575), Expect = 5e-59
Identities = 119/260 (45%), Positives = 162/260 (62%), Gaps = 5/260 (1%)
Query: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Y++ E LG GAFS V ++ S A K I K L ++ +E E + R + HPNI
Sbjct: 98 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKE-ALVENEIAVLRRISHPNI 156
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
V L D YL +LVTGGELF+ I+ R Y+E DASH + Q+L +V+++H IV
Sbjct: 157 VALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIV 216
Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GTPGYLSPEVLRKDPYG 192
HRDLKPENLL A+ + + + ++DFGL+ G G A GTPGY++PE+L + PYG
Sbjct: 217 HRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNM---LGTACGTPGYVAPELLEQKPYG 273
Query: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
K VD+WA GVI YILL GYPPF+DE +L+ QI +Y+F SP WD ++ AK+ I +
Sbjct: 274 KAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHL 333
Query: 253 LTINPAKRITADQALKHPWV 272
L +P KR T QAL+H W+
Sbjct: 334 LERDPQKRFTCQQALRHLWI 353
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,812,544
Number of Sequences: 37866
Number of extensions: 901301
Number of successful extensions: 4773
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 596
Number of HSP's successfully gapped in prelim test: 212
Number of HSP's that attempted gapping in prelim test: 2393
Number of HSP's gapped (non-prelim): 1008
length of query: 504
length of database: 18,247,518
effective HSP length: 107
effective length of query: 397
effective length of database: 14,195,856
effective search space: 5635754832
effective search space used: 5635754832
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.