BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|26667203 calcium/calmodulin-dependent protein kinase II gamma isoform 1 [Homo sapiens] (556 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 1136 0.0 gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 1041 0.0 gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 1004 0.0 gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 983 0.0 gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 976 0.0 gi|26051208 calcium/calmodulin-dependent protein kinase II beta ... 917 0.0 gi|26051210 calcium/calmodulin-dependent protein kinase II beta ... 911 0.0 gi|26051206 calcium/calmodulin-dependent protein kinase II beta ... 902 0.0 gi|26051212 calcium/calmodulin-dependent protein kinase II beta ... 884 0.0 gi|26051216 calcium/calmodulin-dependent protein kinase II beta ... 868 0.0 gi|212549753 calcium/calmodulin-dependent protein kinase II delt... 863 0.0 gi|212549756 calcium/calmodulin-dependent protein kinase II delt... 845 0.0 gi|26667183 calcium/calmodulin-dependent protein kinase II delta... 844 0.0 gi|26667186 calcium/calmodulin-dependent protein kinase II delta... 844 0.0 gi|26667180 calcium/calmodulin-dependent protein kinase II delta... 844 0.0 gi|26667189 calcium/calmodulin-dependent protein kinase II delta... 843 0.0 gi|26051214 calcium/calmodulin-dependent protein kinase II beta ... 814 0.0 gi|25952114 calcium/calmodulin-dependent protein kinase II alpha... 807 0.0 gi|25952118 calcium/calmodulin-dependent protein kinase II alpha... 803 0.0 gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 660 0.0 gi|26051218 calcium/calmodulin-dependent protein kinase II beta ... 603 e-172 gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 275 6e-74 gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 275 6e-74 gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 275 6e-74 gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 242 7e-64 gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 236 5e-62 gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 236 5e-62 gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 233 5e-61 gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca... 226 6e-59 gi|209364619 pregnancy upregulated non-ubiquitously expressed Ca... 226 6e-59 >gi|26667203 calcium/calmodulin-dependent protein kinase II gamma isoform 1 [Homo sapiens] Length = 556 Score = 1136 bits (2939), Expect = 0.0 Identities = 556/556 (100%), Positives = 556/556 (100%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS Sbjct: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL Sbjct: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW Sbjct: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 Query: 541 LNVHYHCSGAPAAPLQ 556 LNVHYHCSGAPAAPLQ Sbjct: 541 LNVHYHCSGAPAAPLQ 556 >gi|26667199 calcium/calmodulin-dependent protein kinase II gamma isoform 3 [Homo sapiens] Length = 518 Score = 1041 bits (2692), Expect = 0.0 Identities = 517/556 (92%), Positives = 518/556 (93%), Gaps = 38/556 (6%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 HNATDGIKGSTESCNTTTEDEDLK Sbjct: 361 HNATDGIKGSTESCNTTTEDEDLK------------------------------------ 384 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 +RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL Sbjct: 385 --VRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 442 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW Sbjct: 443 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 502 Query: 541 LNVHYHCSGAPAAPLQ 556 LNVHYHCSGAPAAPLQ Sbjct: 503 LNVHYHCSGAPAAPLQ 518 >gi|26667211 calcium/calmodulin-dependent protein kinase II gamma isoform 6 [Homo sapiens] Length = 504 Score = 1004 bits (2597), Expect = 0.0 Identities = 503/556 (90%), Positives = 504/556 (90%), Gaps = 52/556 (9%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSL EPQTTVV Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSL--------------EPQTTVV 346 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 HNATDGIKGSTESCNTTTEDEDLK Sbjct: 347 HNATDGIKGSTESCNTTTEDEDLK------------------------------------ 370 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 +RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL Sbjct: 371 --VRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 428 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW Sbjct: 429 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 488 Query: 541 LNVHYHCSGAPAAPLQ 556 LNVHYHCSGAPAAPLQ Sbjct: 489 LNVHYHCSGAPAAPLQ 504 >gi|26667191 calcium/calmodulin-dependent protein kinase II gamma isoform 4 [Homo sapiens] Length = 495 Score = 983 bits (2541), Expect = 0.0 Identities = 494/556 (88%), Positives = 495/556 (89%), Gaps = 61/556 (10%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTMLVSRNFSAAKSLLNKKSDGGVK EPQTTVV Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVK-----------------------EPQTTVV 337 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 HNATDGIKGSTESCNTTTEDEDLK Sbjct: 338 HNATDGIKGSTESCNTTTEDEDLK------------------------------------ 361 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 +RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL Sbjct: 362 --VRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 419 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW Sbjct: 420 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 479 Query: 541 LNVHYHCSGAPAAPLQ 556 LNVHYHCSGAPAAPLQ Sbjct: 480 LNVHYHCSGAPAAPLQ 495 >gi|26667196 calcium/calmodulin-dependent protein kinase II gamma isoform 2 [Homo sapiens] Length = 527 Score = 976 bits (2524), Expect = 0.0 Identities = 495/577 (85%), Positives = 501/577 (86%), Gaps = 71/577 (12%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 Query: 301 KGAILTTMLVSRNFS---------------------AAKSLLNKKSDGGVKPQSNNKNSL 339 KGAILTTMLVSRNFS AAKSLLNKKSDGGVK + ++ + Sbjct: 301 KGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVH 360 Query: 340 VSPAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEG 399 + MEPQTTVVHNATDGIKGSTESCNTTTEDEDLK Sbjct: 361 L------------MEPQTTVVHNATDGIKGSTESCNTTTEDEDLK--------------- 393 Query: 400 RSSRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFE 459 +RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFE Sbjct: 394 -----------------------VRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFE 430 Query: 460 PEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 519 PEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ Sbjct: 431 PEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 490 Query: 520 GRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 556 GRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ Sbjct: 491 GRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 527 >gi|26051208 calcium/calmodulin-dependent protein kinase II beta isoform 3 [Homo sapiens] Length = 518 Score = 917 bits (2370), Expect = 0.0 Identities = 457/557 (82%), Positives = 483/557 (86%), Gaps = 40/557 (7%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNN-KNSLVSPAQEPAPLQTAMEPQTTV 359 KGAILTTML +RNFSAAKSLLNKK+D GVKPQ+N+ KNS + + + A+EPQTTV Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKAD-GVKPQTNSTKNSAAATSPKGTLPPAALEPQTTV 359 Query: 360 VHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLC 419 +HN DGIK S++S NTT EDED KA Sbjct: 360 IHNPVDGIKESSDSANTTIEDEDAKA---------------------------------- 385 Query: 420 SSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFEN 479 RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFEN Sbjct: 386 ----RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFEN 441 Query: 480 LLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK 539 LL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK Sbjct: 442 LLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK 501 Query: 540 WLNVHYHCSGAPAAPLQ 556 W NVH+HCSGAP APLQ Sbjct: 502 WQNVHFHCSGAPVAPLQ 518 >gi|26051210 calcium/calmodulin-dependent protein kinase II beta isoform 4 [Homo sapiens] Length = 517 Score = 911 bits (2354), Expect = 0.0 Identities = 456/557 (81%), Positives = 482/557 (86%), Gaps = 41/557 (7%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNN-KNSLVSPAQEPAPLQTAMEPQTTV 359 KGAILTTML +RNFS AKSLLNKK+D GVKPQ+N+ KNS + + + A+EPQTTV Sbjct: 301 KGAILTTMLATRNFS-AKSLLNKKAD-GVKPQTNSTKNSAAATSPKGTLPPAALEPQTTV 358 Query: 360 VHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLC 419 +HN DGIK S++S NTT EDED KA Sbjct: 359 IHNPVDGIKESSDSANTTIEDEDAKA---------------------------------- 384 Query: 420 SSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFEN 479 RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFEN Sbjct: 385 ----RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFEN 440 Query: 480 LLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK 539 LL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK Sbjct: 441 LLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK 500 Query: 540 WLNVHYHCSGAPAAPLQ 556 W NVH+HCSGAP APLQ Sbjct: 501 WQNVHFHCSGAPVAPLQ 517 >gi|26051206 calcium/calmodulin-dependent protein kinase II beta isoform 2 [Homo sapiens] Length = 542 Score = 902 bits (2331), Expect = 0.0 Identities = 456/581 (78%), Positives = 482/581 (82%), Gaps = 64/581 (11%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDGGVKPQSNN- 335 KGAILTTML +RNFS AKSLLNKK+DG VKPQ+N+ Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADG-VKPQTNST 359 Query: 336 KNSLVSPAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSS 395 KNS + + + A+EPQTTV+HN DGIK S++S NTT EDED KA Sbjct: 360 KNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKA---------- 409 Query: 396 VPEGRSSRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGL 455 RKQEIIK TEQLIEA+NNGDFEAY KICDPGL Sbjct: 410 ----------------------------RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGL 441 Query: 456 TSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQY 515 TSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQY Sbjct: 442 TSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQY 501 Query: 516 IDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 556 IDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ Sbjct: 502 IDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 542 >gi|26051212 calcium/calmodulin-dependent protein kinase II beta isoform 5 [Homo sapiens] Length = 503 Score = 884 bits (2283), Expect = 0.0 Identities = 446/557 (80%), Positives = 471/557 (84%), Gaps = 55/557 (9%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNN-KNSLVSPAQEPAPLQTAMEPQTTV 359 KGAILTTML +RNFSAAKSLLNKK+D GVKPQ+N+ KNS + + + A+E Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKAD-GVKPQTNSTKNSAAATSPKGTLPPAALE----- 354 Query: 360 VHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLC 419 S++S NTT EDED KA Sbjct: 355 ----------SSDSANTTIEDEDAKA---------------------------------- 370 Query: 420 SSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFEN 479 RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFEN Sbjct: 371 ----RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFEN 426 Query: 480 LLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK 539 LL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK Sbjct: 427 LLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGK 486 Query: 540 WLNVHYHCSGAPAAPLQ 556 W NVH+HCSGAP APLQ Sbjct: 487 WQNVHFHCSGAPVAPLQ 503 >gi|26051216 calcium/calmodulin-dependent protein kinase II beta isoform 7 [Homo sapiens] Length = 479 Score = 868 bits (2243), Expect = 0.0 Identities = 437/556 (78%), Positives = 457/556 (82%), Gaps = 77/556 (13%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTML +RNFSAAKSLLNKK+DG Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADG--------------------------------- 327 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 +K S++S NTT EDED KA Sbjct: 328 ------VKESSDSANTTIEDEDAKA----------------------------------- 346 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENL Sbjct: 347 ---RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENL 403 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 L+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW Sbjct: 404 LAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 463 Query: 541 LNVHYHCSGAPAAPLQ 556 NVH+HCSGAP APLQ Sbjct: 464 QNVHFHCSGAPVAPLQ 479 >gi|212549753 calcium/calmodulin-dependent protein kinase II delta isoform 5 [Homo sapiens] Length = 492 Score = 863 bits (2229), Expect = 0.0 Identities = 433/556 (77%), Positives = 464/556 (83%), Gaps = 64/556 (11%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTML +RNFSAAKSLL KK DG EPQTTV+ Sbjct: 301 KGAILTTMLATRNFSAAKSLL-KKPDG------------------------VKEPQTTVI 335 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 HN DG K STES NTT EDED+KA Sbjct: 336 HN-PDGNKESTESSNTTIEDEDVKA----------------------------------- 359 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN Sbjct: 360 ---RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENA 416 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW Sbjct: 417 LSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKW 476 Query: 541 LNVHYHCSGAPAAPLQ 556 NVH+H SG+P P++ Sbjct: 477 QNVHFHRSGSPTVPIK 492 >gi|212549756 calcium/calmodulin-dependent protein kinase II delta isoform 4 [Homo sapiens] Length = 489 Score = 845 bits (2184), Expect = 0.0 Identities = 424/556 (76%), Positives = 459/556 (82%), Gaps = 67/556 (12%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTML +RNFSAAKSLL KK DG K +S++ ++ Sbjct: 301 KGAILTTMLATRNFSAAKSLL-KKPDGVKKRKSSSSVQMME------------------- 340 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 STES NTT EDED+KA Sbjct: 341 ---------STESSNTTIEDEDVKA----------------------------------- 356 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN Sbjct: 357 ---RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENA 413 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW Sbjct: 414 LSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKW 473 Query: 541 LNVHYHCSGAPAAPLQ 556 NVH+H SG+P P++ Sbjct: 474 QNVHFHRSGSPTVPIK 489 >gi|26667183 calcium/calmodulin-dependent protein kinase II delta isoform 1 [Homo sapiens] Length = 478 Score = 844 bits (2180), Expect = 0.0 Identities = 422/556 (75%), Positives = 453/556 (81%), Gaps = 78/556 (14%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTML +RNFSAAKSLL K Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK------------------------------------- 323 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 DG+K STES NTT EDED+KA Sbjct: 324 ---PDGVKESTESSNTTIEDEDVKA----------------------------------- 345 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN Sbjct: 346 ---RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENA 402 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW Sbjct: 403 LSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKW 462 Query: 541 LNVHYHCSGAPAAPLQ 556 NVH+H SG+P P++ Sbjct: 463 QNVHFHRSGSPTVPIK 478 >gi|26667186 calcium/calmodulin-dependent protein kinase II delta isoform 1 [Homo sapiens] Length = 478 Score = 844 bits (2180), Expect = 0.0 Identities = 422/556 (75%), Positives = 453/556 (81%), Gaps = 78/556 (14%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTML +RNFSAAKSLL K Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK------------------------------------- 323 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 DG+K STES NTT EDED+KA Sbjct: 324 ---PDGVKESTESSNTTIEDEDVKA----------------------------------- 345 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN Sbjct: 346 ---RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENA 402 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW Sbjct: 403 LSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKW 462 Query: 541 LNVHYHCSGAPAAPLQ 556 NVH+H SG+P P++ Sbjct: 463 QNVHFHRSGSPTVPIK 478 >gi|26667180 calcium/calmodulin-dependent protein kinase II delta isoform 3 [Homo sapiens] Length = 499 Score = 844 bits (2180), Expect = 0.0 Identities = 422/556 (75%), Positives = 453/556 (81%), Gaps = 78/556 (14%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTML +RNFSAAKSLL K Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK------------------------------------- 323 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 DG+K STES NTT EDED+KA Sbjct: 324 ---PDGVKESTESSNTTIEDEDVKA----------------------------------- 345 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN Sbjct: 346 ---RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENA 402 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW Sbjct: 403 LSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKW 462 Query: 541 LNVHYHCSGAPAAPLQ 556 NVH+H SG+P P++ Sbjct: 463 QNVHFHRSGSPTVPIK 478 >gi|26667189 calcium/calmodulin-dependent protein kinase II delta isoform 2 [Homo sapiens] Length = 478 Score = 843 bits (2179), Expect = 0.0 Identities = 422/555 (76%), Positives = 452/555 (81%), Gaps = 78/555 (14%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360 KGAILTTML +RNFSAAKSLL K Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK------------------------------------- 323 Query: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420 DG+K STES NTT EDED+KA Sbjct: 324 ---PDGVKESTESSNTTIEDEDVKA----------------------------------- 345 Query: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480 RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN Sbjct: 346 ---RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENA 402 Query: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540 LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW Sbjct: 403 LSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKW 462 Query: 541 LNVHYHCSGAPAAPL 555 NVH+H SG+P P+ Sbjct: 463 QNVHFHRSGSPTVPI 477 >gi|26051214 calcium/calmodulin-dependent protein kinase II beta isoform 6 [Homo sapiens] Length = 492 Score = 814 bits (2102), Expect = 0.0 Identities = 422/580 (72%), Positives = 441/580 (76%), Gaps = 112/580 (19%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDGGVKPQSNNK 336 KGAILTTML +RNFS AKSLLNKK+DG Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADG--------- 351 Query: 337 NSLVSPAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSV 396 EPQTTV+HN DGIK S++S NTT EDED KA Sbjct: 352 ---------------VKEPQTTVIHNPVDGIKESSDSANTTIEDEDAKA----------- 385 Query: 397 PEGRSSRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLT 456 RKQEIIK TEQLIEA+NNGDFEAY Sbjct: 386 ---------------------------RKQEIIKTTEQLIEAVNNGDFEAYA-------- 410 Query: 457 SFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYI 516 FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYI Sbjct: 411 ------------------FYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYI 452 Query: 517 DGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 556 DGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ Sbjct: 453 DGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 492 >gi|25952114 calcium/calmodulin-dependent protein kinase II alpha isoform 1 [Homo sapiens] Length = 489 Score = 807 bits (2085), Expect = 0.0 Identities = 402/549 (73%), Positives = 446/549 (81%), Gaps = 66/549 (12%) Query: 4 TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63 T TCTRFT++YQLFEELGKGAFSVVRRCVK + QEYAAKIINTKKLSARDHQKLEREAR Sbjct: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62 Query: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123 ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+ Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122 Query: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183 V H HQ +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182 Query: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243 EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242 Query: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303 EAK+LIN+MLTINP+KRITA +ALKHPW+ RSTVAS MHRQETV+CL+KFNARRKLKGA Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302 Query: 304 ILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVVHNA 363 ILTTML +RNFS KS NKKSDG K +S++ L+ Sbjct: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLME---------------------- 340 Query: 364 TDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCSSAM 423 S+ES NTT EDED K + Sbjct: 341 ------SSESTNTTIEDEDTK--------------------------------------V 356 Query: 424 RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSK 483 RKQEIIK+TEQLIEAI+NGDFE+YTK+CDPG+T+FEPEALGNLVEG+DFH+FYFENL S+ Sbjct: 357 RKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSR 416 Query: 484 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNV 543 NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKW V Sbjct: 417 NSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIV 476 Query: 544 HYHCSGAPA 552 H+H SGAP+ Sbjct: 477 HFHRSGAPS 485 >gi|25952118 calcium/calmodulin-dependent protein kinase II alpha isoform 2 [Homo sapiens] Length = 478 Score = 803 bits (2073), Expect = 0.0 Identities = 400/549 (72%), Positives = 441/549 (80%), Gaps = 77/549 (14%) Query: 4 TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63 T TCTRFT++YQLFEELGKGAFSVVRRCVK + QEYAAKIINTKKLSARDHQKLEREAR Sbjct: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62 Query: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123 ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+ Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122 Query: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183 V H HQ +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182 Query: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243 EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242 Query: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303 EAK+LIN+MLTINP+KRITA +ALKHPW+ RSTVAS MHRQETV+CL+KFNARRKLKGA Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302 Query: 304 ILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVVHNA 363 ILTTML +RNFS KS NKKSDG Sbjct: 303 ILTTMLATRNFSGGKSGGNKKSDG------------------------------------ 326 Query: 364 TDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCSSAM 423 +K S+ES NTT EDED K + Sbjct: 327 ---VKESSESTNTTIEDEDTK--------------------------------------V 345 Query: 424 RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSK 483 RKQEIIK+TEQLIEAI+NGDFE+YTK+CDPG+T+FEPEALGNLVEG+DFH+FYFENL S+ Sbjct: 346 RKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSR 405 Query: 484 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNV 543 NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKW V Sbjct: 406 NSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIV 465 Query: 544 HYHCSGAPA 552 H+H SGAP+ Sbjct: 466 HFHRSGAPS 474 >gi|26051204 calcium/calmodulin-dependent protein kinase II beta isoform 1 [Homo sapiens] Length = 666 Score = 660 bits (1704), Expect = 0.0 Identities = 341/449 (75%), Positives = 369/449 (82%), Gaps = 34/449 (7%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDGGVKPQSNN- 335 KGAILTTML +RNFS AKSLLNKK+D GVKPQ+N+ Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKAD-GVKPQTNST 359 Query: 336 KNSLVSPAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKA-------APL 388 KNS + + + A+EPQTTV+HN DGIK S++S NTT EDED KA + + Sbjct: 360 KNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKAPRVPDILSSV 419 Query: 389 RTGNGSSVPEGRSSRDRTAPSAGMQPQPS 417 R G+G+ EG AP + + P PS Sbjct: 420 RRGSGAPEAEGPLPCPSPAPFSPL-PAPS 447 Score = 274 bits (700), Expect = 2e-73 Identities = 131/164 (79%), Positives = 136/164 (82%) Query: 393 GSSVPEGRSSRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICD 452 GS PE P P + RKQEIIK TEQLIEA+NNGDFEAY KICD Sbjct: 503 GSGTPEAEGPSPVGPPPCPSPTIPGPLPTPSRKQEIIKTTEQLIEAVNNGDFEAYAKICD 562 Query: 453 PGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRL 512 PGLTSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRL Sbjct: 563 PGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRL 622 Query: 513 TQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 556 TQYIDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ Sbjct: 623 TQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 666 >gi|26051218 calcium/calmodulin-dependent protein kinase II beta isoform 8 [Homo sapiens] Length = 449 Score = 603 bits (1555), Expect = e-172 Identities = 297/356 (83%), Positives = 319/356 (89%), Gaps = 2/356 (0%) Query: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60 MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60 Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120 EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120 Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180 LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180 Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240 Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300 VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300 Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQ 356 KGAILTTML +RNFSA K + K ++ ++ +N + +P T+ EP+ Sbjct: 301 KGAILTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPG--LTSFEPE 354 Score = 269 bits (688), Expect = 4e-72 Identities = 125/133 (93%), Positives = 129/133 (96%) Query: 424 RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSK 483 RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+K Sbjct: 317 RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAK 376 Query: 484 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNV 543 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NV Sbjct: 377 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNV 436 Query: 544 HYHCSGAPAAPLQ 556 H+HCSGAP APLQ Sbjct: 437 HFHCSGAPVAPLQ 449 >gi|186700629 calcium/calmodulin-dependent serine protein kinase isoform 3 [Homo sapiens] Length = 897 Score = 275 bits (704), Expect = 6e-74 Identities = 141/306 (46%), Positives = 205/306 (66%), Gaps = 8/306 (2%) Query: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSAR---DHQKLEREARICR 66 F D Y+L E +GKG FSVVRRC+ + + Q++A KI++ K ++ + L+REA IC Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67 Query: 67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIHQILE 122 +LKHP+IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH + QILE Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127 Query: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182 ++ + H ++I+HRD+KP +LLASK A VKL FG+AI++ G GTP +++ Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187 Query: 183 PEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242 PEV++++PYGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++ Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246 Query: 243 PEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKG 302 AK+L+ +ML ++PA+RIT +AL HPW+ +R A +H ETVE LRKFNARRKLKG Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306 Query: 303 AILTTM 308 A+L + Sbjct: 307 AVLAAV 312 >gi|186700627 calcium/calmodulin-dependent serine protein kinase isoform 2 [Homo sapiens] Length = 898 Score = 275 bits (704), Expect = 6e-74 Identities = 141/306 (46%), Positives = 205/306 (66%), Gaps = 8/306 (2%) Query: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSAR---DHQKLEREARICR 66 F D Y+L E +GKG FSVVRRC+ + + Q++A KI++ K ++ + L+REA IC Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67 Query: 67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIHQILE 122 +LKHP+IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH + QILE Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127 Query: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182 ++ + H ++I+HRD+KP +LLASK A VKL FG+AI++ G GTP +++ Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187 Query: 183 PEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242 PEV++++PYGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++ Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246 Query: 243 PEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKG 302 AK+L+ +ML ++PA+RIT +AL HPW+ +R A +H ETVE LRKFNARRKLKG Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306 Query: 303 AILTTM 308 A+L + Sbjct: 307 AVLAAV 312 >gi|186972120 calcium/calmodulin-dependent serine protein kinase isoform 1 [Homo sapiens] Length = 921 Score = 275 bits (704), Expect = 6e-74 Identities = 141/306 (46%), Positives = 205/306 (66%), Gaps = 8/306 (2%) Query: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSAR---DHQKLEREARICR 66 F D Y+L E +GKG FSVVRRC+ + + Q++A KI++ K ++ + L+REA IC Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67 Query: 67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIHQILE 122 +LKHP+IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH + QILE Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127 Query: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182 ++ + H ++I+HRD+KP +LLASK A VKL FG+AI++ G GTP +++ Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187 Query: 183 PEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242 PEV++++PYGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++ Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246 Query: 243 PEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKG 302 AK+L+ +ML ++PA+RIT +AL HPW+ +R A +H ETVE LRKFNARRKLKG Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306 Query: 303 AILTTM 308 A+L + Sbjct: 307 AVLAAV 312 >gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo sapiens] Length = 473 Score = 242 bits (617), Expect = 7e-64 Identities = 141/351 (40%), Positives = 213/351 (60%), Gaps = 23/351 (6%) Query: 11 TDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKH 70 +D +++ ELG+GA S+V RC +K + + YA K++ D + + E + L H Sbjct: 43 SDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK----KTVDKKIVRTEIGVLLRLSH 98 Query: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130 PNI++L + LV +LVTGGELF+ IV + YYSE DA+ + QILE+V ++H++ Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158 Query: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDP 190 IVHRDLKPENLL A+ A +K+ADFGL+ ++ Q GTPGY +PE+LR Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLS-KIVEHQVLMKTVCGTPGYCAPEILRGCA 217 Query: 191 YGKPVDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248 YG VD+W+ G+I YILL G+ PF+DE DQ ++++I Y F SP WD V+ AK+L Sbjct: 218 YGPEVDMWSVGIITYILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDL 276 Query: 249 INQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTM 308 + +++ ++P KR+T QAL+HPWV ++ A+ +H + L++FNARRKLK A+ + Sbjct: 277 VRKLIVLDPKKRLTTFQALQHPWVTGKA--ANFVHMDTAQKKLQEFNARRKLKAAVKAVV 334 Query: 309 LVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTV 359 SR SA+ S G + Q ++K S ++P+P+Q E + Sbjct: 335 ASSRLGSAS------SSHGSI--QESHKAS-----RDPSPIQDGNEDMKAI 372 >gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1 [Homo sapiens] Length = 357 Score = 236 bits (601), Expect = 5e-62 Identities = 123/297 (41%), Positives = 183/297 (61%), Gaps = 3/297 (1%) Query: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73 ++ E LG GAFS V +K + + +A K I K L ++ +E E + R +KH NI Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81 Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133 V L D YLV LV+GGELF+ IV + +Y+E DAS I Q+L++V ++H+ IV Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141 Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK 193 HRDLKPENLL S+ + + + ++DFGL+ +++G+ GTPGY++PEVL + PY K Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200 Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253 VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I ++ Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260 Query: 254 TINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLV 310 +P KR T +QA +HPW+ + + +H + + +RK A+ K + A T +V Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQ-IRKNFAKSKWRQAFNATAVV 316 >gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform 2 [Homo sapiens] Length = 385 Score = 236 bits (601), Expect = 5e-62 Identities = 123/297 (41%), Positives = 183/297 (61%), Gaps = 3/297 (1%) Query: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73 ++ E LG GAFS V +K + + +A K I K L ++ +E E + R +KH NI Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81 Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133 V L D YLV LV+GGELF+ IV + +Y+E DAS I Q+L++V ++H+ IV Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141 Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK 193 HRDLKPENLL S+ + + + ++DFGL+ +++G+ GTPGY++PEVL + PY K Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200 Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253 VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I ++ Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260 Query: 254 TINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLV 310 +P KR T +QA +HPW+ + + +H + + +RK A+ K + A T +V Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQ-IRKNFAKSKWRQAFNATAVV 316 >gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo sapiens] Length = 370 Score = 233 bits (593), Expect = 5e-61 Identities = 125/299 (41%), Positives = 179/299 (59%), Gaps = 3/299 (1%) Query: 12 DDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71 D Y + LG GAFS V K + + A K I + L ++ +E E + +KHP Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS-MENEIAVLHKIKHP 76 Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131 NIV L D G YL+ LV+GGELF+ IV + +Y+E DAS I Q+L++V ++H Sbjct: 77 NIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLG 136 Query: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY 191 IVHRDLKPENLL S + + + ++DFGL+ +++ GTPGY++PEVL + PY Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLS-KMEDPGSVLSTACGTPGYVAPEVLAQKPY 195 Query: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251 K VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRH 255 Query: 252 MLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLV 310 ++ +P KR T +QAL+HPW+ + + +H Q E ++K A+ K K A T +V Sbjct: 256 LMEKDPEKRFTCEQALQHPWIAGDTALDKNIH-QSVSEQIKKNFAKSKWKQAFNATAVV 313 >gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM kinase isoform b [Homo sapiens] Length = 360 Score = 226 bits (575), Expect = 6e-59 Identities = 119/260 (45%), Positives = 162/260 (62%), Gaps = 5/260 (1%) Query: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73 Y++ E LG GAFS V ++ S A K I K L ++ +E E + R + HPNI Sbjct: 32 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKE-ALVENEIAVLRRISHPNI 90 Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133 V L D YL +LVTGGELF+ I+ R Y+E DASH + Q+L +V+++H IV Sbjct: 91 VALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIV 150 Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GTPGYLSPEVLRKDPYG 192 HRDLKPENLL A+ + + + ++DFGL+ G G A GTPGY++PE+L + PYG Sbjct: 151 HRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNM---LGTACGTPGYVAPELLEQKPYG 207 Query: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252 K VD+WA GVI YILL GYPPF+DE +L+ QI +Y+F SP WD ++ AK+ I + Sbjct: 208 KAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHL 267 Query: 253 LTINPAKRITADQALKHPWV 272 L +P KR T QAL+H W+ Sbjct: 268 LERDPQKRFTCQQALRHLWI 287 >gi|209364619 pregnancy upregulated non-ubiquitously expressed CaM kinase isoform a [Homo sapiens] Length = 426 Score = 226 bits (575), Expect = 6e-59 Identities = 119/260 (45%), Positives = 162/260 (62%), Gaps = 5/260 (1%) Query: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73 Y++ E LG GAFS V ++ S A K I K L ++ +E E + R + HPNI Sbjct: 98 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKE-ALVENEIAVLRRISHPNI 156 Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133 V L D YL +LVTGGELF+ I+ R Y+E DASH + Q+L +V+++H IV Sbjct: 157 VALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIV 216 Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GTPGYLSPEVLRKDPYG 192 HRDLKPENLL A+ + + + ++DFGL+ G G A GTPGY++PE+L + PYG Sbjct: 217 HRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNM---LGTACGTPGYVAPELLEQKPYG 273 Query: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252 K VD+WA GVI YILL GYPPF+DE +L+ QI +Y+F SP WD ++ AK+ I + Sbjct: 274 KAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHL 333 Query: 253 LTINPAKRITADQALKHPWV 272 L +P KR T QAL+H W+ Sbjct: 334 LERDPQKRFTCQQALRHLWI 353 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,527,064 Number of Sequences: 37866 Number of extensions: 1071763 Number of successful extensions: 5762 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 603 Number of HSP's successfully gapped in prelim test: 224 Number of HSP's that attempted gapping in prelim test: 3311 Number of HSP's gapped (non-prelim): 1099 length of query: 556 length of database: 18,247,518 effective HSP length: 107 effective length of query: 449 effective length of database: 14,195,856 effective search space: 6373939344 effective search space used: 6373939344 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.