Search of human proteins with 26051260

Search of human proteins with 26051260

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26051260 potassium voltage-gated channel KQT-like protein 2
isoform c [Homo sapiens]
         (844 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26051260 potassium voltage-gated channel KQT-like protein 2 i...  1717   0.0  
gi|26051262 potassium voltage-gated channel KQT-like protein 2 i...  1709   0.0  
gi|26051264 potassium voltage-gated channel KQT-like protein 2 i...  1698   0.0  
gi|26051266 potassium voltage-gated channel KQT-like protein 2 i...  1672   0.0  
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i...   761   0.0  
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,...   683   0.0  
gi|236461942 potassium voltage-gated channel, KQT-like subfamily...   677   0.0  
gi|236462079 potassium voltage-gated channel, KQT-like subfamily...   676   0.0  
gi|236461719 potassium voltage-gated channel, KQT-like subfamily...   672   0.0  
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i...   672   0.0  
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H...   670   0.0  
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i...   665   0.0  
gi|236462242 potassium voltage-gated channel, KQT-like subfamily...   472   e-133
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,...   405   e-112
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,...   379   e-105
gi|21217561 Shaw-related voltage-gated potassium channel protein...   104   3e-22
gi|21217563 Shaw-related voltage-gated potassium channel protein...   104   3e-22
gi|24497458 Shaw-related voltage-gated potassium channel protein...   104   3e-22
gi|119395748 potassium voltage-gated channel subfamily A member ...    95   3e-19
gi|88758565 potassium voltage-gated channel, shaker-related subf...    94   5e-19
gi|4504817 potassium voltage-gated channel, shaker-related subfa...    94   5e-19
gi|4826784 potassium voltage-gated channel, Shab-related subfami...    92   2e-18
gi|27436974 potassium voltage-gated channel, Shab-related subfam...    92   3e-18
gi|4826786 Shaw-related voltage-gated potassium channel protein ...    91   4e-18
gi|163792201 Shaw-related voltage-gated potassium channel protei...    91   4e-18
gi|88758576 Shaw-related voltage-gated potassium channel protein...    90   1e-17
gi|24497462 Shaw-related voltage-gated potassium channel protein...    90   1e-17
gi|24497464 Shaw-related voltage-gated potassium channel protein...    90   1e-17
gi|4504821 potassium voltage-gated channel, shaker-related subfa...    89   2e-17
gi|4826782 potassium voltage-gated channel, shaker-related subfa...    89   2e-17

>gi|26051260 potassium voltage-gated channel KQT-like protein 2
           isoform c [Homo sapiens]
          Length = 844

 Score = 1717 bits (4447), Expect = 0.0
 Identities = 844/844 (100%), Positives = 844/844 (100%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMYRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRVFSSPR 420
           QYYERTVTVPMYRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRVFSSPR
Sbjct: 361 QYYERTVTVPMYRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRVFSSPR 420

Query: 421 GVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE 480
           GVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE
Sbjct: 421 GVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE 480

Query: 481 EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVI 540
           EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVI
Sbjct: 481 EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVI 540

Query: 541 EQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPSMMGRLGKVEK 600
           EQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPSMMGRLGKVEK
Sbjct: 541 EQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPSMMGRLGKVEK 600

Query: 601 QVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVK 660
           QVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVK
Sbjct: 601 QVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVK 660

Query: 661 IVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGSLVRIPPPPAH 720
           IVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGSLVRIPPPPAH
Sbjct: 661 IVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGSLVRIPPPPAH 720

Query: 721 ERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSIS 780
           ERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSIS
Sbjct: 721 ERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSIS 780

Query: 781 QSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWA 840
           QSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWA
Sbjct: 781 QSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWA 840

Query: 841 GPRK 844
           GPRK
Sbjct: 841 GPRK 844


>gi|26051262 potassium voltage-gated channel KQT-like protein 2
           isoform b [Homo sapiens]
          Length = 854

 Score = 1709 bits (4426), Expect = 0.0
 Identities = 844/854 (98%), Positives = 844/854 (98%), Gaps = 10/854 (1%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMY----------RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS 410
           QYYERTVTVPMY          RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS
Sbjct: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS 420

Query: 411 LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 470
           LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI
Sbjct: 421 LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 480

Query: 471 KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 530
           KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES
Sbjct: 481 KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 540

Query: 531 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 590
           LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS
Sbjct: 541 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 600

Query: 591 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 650
           MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE
Sbjct: 601 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 660

Query: 651 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 710
           HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS
Sbjct: 661 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 720

Query: 711 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 770
           LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL
Sbjct: 721 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 780

Query: 771 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 830
           ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG
Sbjct: 781 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 840

Query: 831 EGPFGDVGWAGPRK 844
           EGPFGDVGWAGPRK
Sbjct: 841 EGPFGDVGWAGPRK 854


>gi|26051264 potassium voltage-gated channel KQT-like protein 2
           isoform a [Homo sapiens]
          Length = 872

 Score = 1698 bits (4397), Expect = 0.0
 Identities = 844/872 (96%), Positives = 844/872 (96%), Gaps = 28/872 (3%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMY----------RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPS---- 406
           QYYERTVTVPMY          RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPS    
Sbjct: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSKGSP 420

Query: 407 --------------QKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKV 452
                         QKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKV
Sbjct: 421 CRGPLCGCCPGRSSQKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKV 480

Query: 453 PKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI 512
           PKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI
Sbjct: 481 PKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI 540

Query: 513 RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAIT 572
           RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAIT
Sbjct: 541 RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAIT 600

Query: 573 DKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFG 632
           DKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFG
Sbjct: 601 DKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFG 660

Query: 633 AKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQP 692
           AKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQP
Sbjct: 661 AKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQP 720

Query: 693 QSHPRQGHGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGN 752
           QSHPRQGHGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGN
Sbjct: 721 QSHPRQGHGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGN 780

Query: 753 LRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESD 812
           LRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESD
Sbjct: 781 LRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESD 840

Query: 813 TDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK 844
           TDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK
Sbjct: 841 TDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK 872


>gi|26051266 potassium voltage-gated channel KQT-like protein 2
           isoform d [Homo sapiens]
          Length = 841

 Score = 1672 bits (4330), Expect = 0.0
 Identities = 831/854 (97%), Positives = 831/854 (97%), Gaps = 23/854 (2%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMY----------RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS 410
           QYYERTVTVPMY          RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP     
Sbjct: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP----- 415

Query: 411 LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 470
                  SPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI
Sbjct: 416 -------SPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 468

Query: 471 KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 530
           KGAASRQNS EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES
Sbjct: 469 KGAASRQNS-EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 527

Query: 531 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 590
           LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS
Sbjct: 528 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 587

Query: 591 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 650
           MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE
Sbjct: 588 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 647

Query: 651 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 710
           HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS
Sbjct: 648 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 707

Query: 711 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 770
           LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL
Sbjct: 708 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 767

Query: 771 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 830
           ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG
Sbjct: 768 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 827

Query: 831 EGPFGDVGWAGPRK 844
           EGPFGDVGWAGPRK
Sbjct: 828 EGPFGDVGWAGPRK 841


>gi|26051268 potassium voltage-gated channel KQT-like protein 2
           isoform e [Homo sapiens]
          Length = 393

 Score =  761 bits (1964), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMYR 373
           QYYERTVTVPMYR
Sbjct: 361 QYYERTVTVPMYR 373


>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 1 [Homo sapiens]
          Length = 932

 Score =  683 bits (1763), Expect = 0.0
 Identities = 380/669 (56%), Positives = 459/669 (68%), Gaps = 52/669 (7%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPP 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +             E++V++  ++  P 
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAAD-------------EKSVSIATWK--PH 396

Query: 378 LNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKGKGSPQAQTVR 436
           L  L      K + G         E S SQK+S K+RV  +SPRG + K + +      R
Sbjct: 397 LKALHTCSPTKKEQG---------EASSSQKLSFKERVRMASPRGQSIKSRQASVGD--R 445

Query: 437 RSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLPGEDIVDDKSC 495
           RSPS D + E SP+KV KSWSF DR+R R + R+K +  +   + + +L  +D+ D+K C
Sbjct: 446 RSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGC 505

Query: 496 PCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIK 555
            C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIK
Sbjct: 506 QCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIK 565

Query: 556 SLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVN 614
           SLQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++
Sbjct: 566 SLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLD 625

Query: 615 IYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSS 667
           IY Q  R G       A F     E E    Y SP DS++        GC+ +   ++ S
Sbjct: 626 IYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANIS 685

Query: 668 TGQKNFSAP 676
            G +    P
Sbjct: 686 RGLQFILTP 694


>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 3 [Homo sapiens]
          Length = 942

 Score =  677 bits (1748), Expect = 0.0
 Identities = 378/671 (56%), Positives = 460/671 (68%), Gaps = 46/671 (6%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTV--PMYRLI 375
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +    P  +  
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTNKFC 410

Query: 376 PPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKGKGSPQAQT 434
              N+ +L R   S+               SQK+S K+RV  +SPRG + K + +     
Sbjct: 411 S--NKQKLFRMYTSR-------------KQSQKLSFKERVRMASPRGQSIKSRQASVGD- 454

Query: 435 VRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLPGEDIVDDK 493
            RRSPS D + E SP+KV KSWSF DR+R R + R+K +  +   + + +L  +D+ D+K
Sbjct: 455 -RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEK 513

Query: 494 SCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSR 553
            C C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML R
Sbjct: 514 GCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCR 573

Query: 554 IKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFL 612
           IKSLQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S+E KLD L
Sbjct: 574 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 633

Query: 613 VNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSS 665
           ++IY Q  R G       A F     E E    Y SP DS++        GC+ +   ++
Sbjct: 634 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 693

Query: 666 SSTGQKNFSAP 676
            S G +    P
Sbjct: 694 ISRGLQFILTP 704


>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 4 [Homo sapiens]
          Length = 951

 Score =  676 bits (1744), Expect = 0.0
 Identities = 381/681 (55%), Positives = 460/681 (67%), Gaps = 57/681 (8%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPP 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +             E++V++  ++  P 
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAAD-------------EKSVSIATWK--PH 396

Query: 378 LNQLELLRNLKSKSGLA------------FRKDPPPEPSPSQKVSLKDRV-FSSPRGVAA 424
           L  L      K + G A            FR         SQK+S K+RV  +SPRG + 
Sbjct: 397 LKALHTCSPTKKEQGEASSSKFCSNKQKLFRM--YTSRKQSQKLSFKERVRMASPRGQSI 454

Query: 425 KGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EAS 483
           K + +      RRSPS D + E SP+KV KSWSF DR+R R + R+K +  +   + + +
Sbjct: 455 KSRQASVGD--RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTA 512

Query: 484 LPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQY 543
           L  +D+ D+K C C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQY
Sbjct: 513 LGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQY 572

Query: 544 SAGHLDMLSRIKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQV 602
           SAGHLDML RIKSLQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV
Sbjct: 573 SAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQV 632

Query: 603 LSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRH 655
            S+E KLD L++IY Q  R G       A F     E E    Y SP DS++        
Sbjct: 633 QSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNS 692

Query: 656 GCIVKIVRSSSSTGQKNFSAP 676
           GC+ +   ++ S G +    P
Sbjct: 693 GCLSRSTSANISRGLQFILTP 713


>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 2 [Homo sapiens]
          Length = 923

 Score =  672 bits (1734), Expect = 0.0
 Identities = 377/670 (56%), Positives = 456/670 (68%), Gaps = 63/670 (9%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPP 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +             E++V++  ++  P 
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAAD-------------EKSVSIATWK--PH 396

Query: 378 LNQLELLRNLKSKSGLAFRKDPPPEPSP-SQKVSLKDRV-FSSPRGVAAKGKGSPQAQTV 435
           L  L                      SP +QK+S K+RV  +SPRG + K + +      
Sbjct: 397 LKALHTC-------------------SPTNQKLSFKERVRMASPRGQSIKSRQASVGD-- 435

Query: 436 RRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLPGEDIVDDKS 494
           RRSPS D + E SP+KV KSWSF DR+R R + R+K +  +   + + +L  +D+ D+K 
Sbjct: 436 RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKG 495

Query: 495 CPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRI 554
           C C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RI
Sbjct: 496 CQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRI 555

Query: 555 KSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLV 613
           KSLQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S+E KLD L+
Sbjct: 556 KSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLL 615

Query: 614 NIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSS 666
           +IY Q  R G       A F     E E    Y SP DS++        GC+ +   ++ 
Sbjct: 616 DIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 675

Query: 667 STGQKNFSAP 676
           S G +    P
Sbjct: 676 SRGLQFILTP 685


>gi|26638653 potassium voltage-gated channel KQT-like protein 4
           isoform a [Homo sapiens]
          Length = 695

 Score =  672 bits (1733), Expect = 0.0
 Identities = 363/669 (54%), Positives = 462/669 (69%), Gaps = 59/669 (8%)

Query: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97

Query: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157

Query: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217

Query: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277

Query: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337

Query: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELL--RNLKS 389
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+         ++P   +L LL     ++
Sbjct: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD--------SILPSFRELALLFEHVQRA 389

Query: 390 KSG----LAFRKDPPPEPSPSQ---------------------KVSLKDRV-FSSPRGVA 423
           ++G    L  R+ P P+ +PS+                     ++ +KDR+   S +   
Sbjct: 390 RNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRT 449

Query: 424 AKGKGSPQAQTVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEA 482
              K      T+  SPS++Q  E  SP+KV KSWSF DR+R R + R+K    R ++E+A
Sbjct: 450 GPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLK---PRTSAEDA 506

Query: 483 SLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQ 542
             P E++ ++KS  CE   +D+ P +K  IR++ +++FLV+KRKFKE+LRPYDV DVIEQ
Sbjct: 507 --PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQ 564

Query: 543 YSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDPSMMGRLGKVEK 600
           YSAGHLDML RIKSLQ+RVDQIVGRGP      +   KGP++AE+ ++ SMMGR+ KVEK
Sbjct: 565 YSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEK 624

Query: 601 QVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCI 658
           QV S+E KLD L+  Y +  R G   +         +P+    YHSP D  E +      
Sbjct: 625 QVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD-HEDISVSAQT 683

Query: 659 VKIVRSSSS 667
           + I RS S+
Sbjct: 684 LSISRSVST 692


>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
           sapiens]
          Length = 872

 Score =  670 bits (1728), Expect = 0.0
 Identities = 419/897 (46%), Positives = 530/897 (59%), Gaps = 121/897 (13%)

Query: 4   KSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGS-------EAPKRGSILSK 56
           + R  G+ PG   +  L +G  G D       +DG LL+ G          P+   +L+K
Sbjct: 39  EERKVGLAPGDVEQVTLALG-AGAD-------KDGTLLLEGGGRDEGQRRTPQGIGLLAK 90

Query: 57  PRAGGAGAGKPPKRN-AFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTI 115
                    +P KRN A YR++Q  +Y+ LERPRGWA +YHA VFL+V  CL+L+V +T 
Sbjct: 91  -----TPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTF 145

Query: 116 KEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMV 175
           KEYE  S   L +LE   I +FG E+ +RIWAAGCCCRY+GWRGRLKFARKP C++DI V
Sbjct: 146 KEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFV 205

Query: 176 LIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
           LIAS+ V+A G+QGNV ATS LRSLRFLQILRM+RMDRRGGTWKLLGS + AHSKEL+TA
Sbjct: 206 LIASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITA 264

Query: 236 WYIGFLCLILASFLVYLAEK--------GEN--DHFDTYADALWWGLITLTTIGYGDKYP 285
           WYIGFL LIL+SFLVYL EK        GE   + F+TYADALWWGLITL TIGYGDK P
Sbjct: 265 WYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTP 324

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
           +TW GRL+AATF+LIGVSFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQ+AWR
Sbjct: 325 KTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWR 384

Query: 346 FYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP 405
           +YATN +R DL +TW++YE  V+ P +R      QL                    E + 
Sbjct: 385 YYATNPNRIDLVATWRFYESVVSFPFFR----KEQL--------------------EAAS 420

Query: 406 SQKVSLKDRV-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRA 464
           SQK+ L DRV  S+PRG   KGK          +P    ++E+SPSK PK     ++ R 
Sbjct: 421 SQKLGLLDRVRLSNPRGSNTKGK--------LFTPLNVDAIEESPSKEPKPVGLNNKERF 472

Query: 465 RQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSK 524
           R AFR+K  A  Q+SE+A   G+ + +D+    +F  ED+ P LK +IRAV +++F + K
Sbjct: 473 RTAFRMKAYAFWQSSEDAG-TGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYK 531

Query: 525 RKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDR--TKG--- 579
           +KFKE+LRPYDV DVIEQYSAGHLDMLSRIK LQ+R+D I   GP  T K +   KG   
Sbjct: 532 KKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAF 591

Query: 580 ----------------PAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIP 623
                           P+ +E+ ED SMMG+  KVE+QV  M KKLDFLV+++MQ M   
Sbjct: 592 TFPSQQSPRNEPYVARPSTSEI-EDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERL 650

Query: 624 PTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQ 683
             +   Y+  K           ED     +R+  +  I+ + S TG       P  PP  
Sbjct: 651 QVQVTEYYPTKGTSSPAEAEKKED-----NRYSDLKTIICNYSETG-------PPEPPYS 698

Query: 684 CPPST----------SWQPQSHPRQG------HGTSPVGDHGSLVRIPPPPAHERSLSAY 727
               T          +  P + PR G        T P      + R    P      S  
Sbjct: 699 FHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRV 758

Query: 728 GGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD 787
              ++A ++     D    R      RDSDT +S+ SV+HEELERS SGFSISQ +++  
Sbjct: 759 SCHSQADLQG-PYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYV 817

Query: 788 ALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK 844
              +     +   + + Y+AEGE+DTD+D  TP G  P S+TG+G   D  W    K
Sbjct: 818 FGPN---GGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDG-ISDSVWTPSNK 870


>gi|26638655 potassium voltage-gated channel KQT-like protein 4
           isoform b [Homo sapiens]
          Length = 641

 Score =  665 bits (1715), Expect = 0.0
 Identities = 355/642 (55%), Positives = 444/642 (69%), Gaps = 59/642 (9%)

Query: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97

Query: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157

Query: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217

Query: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277

Query: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337

Query: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELLRNLKSKS 391
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+  +                        
Sbjct: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSIL------------------------ 373

Query: 392 GLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLE-DSP 449
                      PS S ++ +KDR+   S +      K      T+  SPS++Q  E  SP
Sbjct: 374 -----------PSFSSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSP 422

Query: 450 SKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLK 509
           +KV KSWSF DR+R R + R+K    R ++E+A  P E++ ++KS  CE   +D+ P +K
Sbjct: 423 TKVQKSWSFNDRTRFRASLRLK---PRTSAEDA--PSEEVAEEKSYQCELTVDDIMPAVK 477

Query: 510 VSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGP 569
             IR++ +++FLV+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP
Sbjct: 478 TVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGP 537

Query: 570 A--ITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPT 625
                 +   KGP++AE+ ++ SMMGR+ KVEKQV S+E KLD L+  Y +  R G   +
Sbjct: 538 GDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSAS 597

Query: 626 ETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSS 667
                    +P+    YHSP D  E +      + I RS S+
Sbjct: 598 LGAVQVPLFDPDITSDYHSPVD-HEDISVSAQTLSISRSVST 638


>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 5 [Homo sapiens]
          Length = 822

 Score =  472 bits (1214), Expect = e-133
 Identities = 238/344 (69%), Positives = 271/344 (78%), Gaps = 17/344 (4%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQ 361
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWK 394



 Score =  138 bits (347), Expect = 2e-32
 Identities = 85/168 (50%), Positives = 106/168 (63%), Gaps = 8/168 (4%)

Query: 517 VMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITD-KD 575
           +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQI+G+G   +D K 
Sbjct: 417 IMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKS 476

Query: 576 RTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGA 633
           R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++IY Q  R G       A F  
Sbjct: 477 REKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQI 536

Query: 634 K--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQKNFSAP 676
              E E    Y SP DS++        GC+ +   ++ S G +    P
Sbjct: 537 PPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTP 584


>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 1 [Homo sapiens]
          Length = 676

 Score =  405 bits (1040), Expect = e-112
 Identities = 241/605 (39%), Positives = 354/605 (58%), Gaps = 57/605 (9%)

Query: 29  PGAPDSTRDGALLIAGSEAPKRGSILSKPRAGGAGAGKPPKRNAFYRKLQNFLYNVLERP 88
           P  P S    A     S+   R  +   PR       +P         +Q  +YN LERP
Sbjct: 61  PAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTH---VQGRVYNFLERP 117

Query: 89  RGW-AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWA 147
            GW  F+YH  VFL+V  CL+ SV STI++Y   + G L+ +EIV +V FG EY VR+W+
Sbjct: 118 TGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWS 177

Query: 148 AGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILR 207
           AGC  +Y G  GRL+FARKP  +ID++V++AS+ VL  GS+G VFATSA+R +RFLQILR
Sbjct: 178 AGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILR 237

Query: 208 MIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFD 262
           M+ +DR+GGTW+LLGSVV+ H +EL+T  YIGFL LI +S+ VYLAEK   +      F 
Sbjct: 238 MLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFG 297

Query: 263 TYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQE 322
           +YADALWWG++T+TTIGYGDK PQTW G+ +A+ F++  +SFFALPAGILGSGFALKVQ+
Sbjct: 298 SYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQ 357

Query: 323 QHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLE 382
           + RQKHF ++   AA LIQ+AWR YA   +     STW+ Y R      + L+ P  + +
Sbjct: 358 KQRQKHFNRQIPAAASLIQTAWRCYA---AENPDSSTWKIYIRKAP-RSHTLLSPSPKPK 413

Query: 383 LLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRVFSSPRGVAAKGKGSPQA--QTVRRSPS 440
               +K K    F+ D     +P +K+     +   P         S      +VR+SP+
Sbjct: 414 KSVVVKKKK---FKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPT 470

Query: 441 ADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFV 500
               LE S     ++ SF                    +E+  L GE ++     P   +
Sbjct: 471 L---LEVSMPHFMRTNSF--------------------AEDLDLEGETLL----TPITHI 503

Query: 501 TEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSR 560
           ++ L    + +I+ +  M++ V+K+KF+++ +PYDV DVIEQYS GHL+++ RIK LQ R
Sbjct: 504 SQ-LREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRR 562

Query: 561 VDQIVGRGP---AITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYM 617
           +DQ +G+     ++++K + +G          ++  RL +VE +V  ++++L  + ++  
Sbjct: 563 LDQSIGKPSLFISVSEKSKDRG--------SNTIGARLNRVEDKVTQLDQRLALITDMLH 614

Query: 618 QRMGI 622
           Q + +
Sbjct: 615 QLLSL 619


>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 2 [Homo sapiens]
          Length = 549

 Score =  379 bits (974), Expect = e-105
 Identities = 219/533 (41%), Positives = 326/533 (61%), Gaps = 53/533 (9%)

Query: 100 FLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
           FL+V  CL+ SV STI++Y   + G L+ +EIV +V FG EY VR+W+AGC  +Y G  G
Sbjct: 3   FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62

Query: 160 RLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWK 219
           RL+FARKP  +ID++V++AS+ VL  GS+G VFATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 63  RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122

Query: 220 LLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFDTYADALWWGLIT 274
           LLGSVV+ H +EL+T  YIGFL LI +S+ VYLAEK   +      F +YADALWWG++T
Sbjct: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182

Query: 275 LTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRN 334
           +TTIGYGDK PQTW G+ +A+ F++  +SFFALPAGILGSGFALKVQ++ RQKHF ++  
Sbjct: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242

Query: 335 PAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELLRNLKSKSGLA 394
            AA LIQ+AWR YA   +     STW+ Y R      + L+ P  + +    +K K    
Sbjct: 243 AAASLIQTAWRCYA---AENPDSSTWKIYIRKAP-RSHTLLSPSPKPKKSVVVKKKK--- 295

Query: 395 FRKDPPPEPSPSQKVSLKDRVFSSPRGVAAKGKGSPQA--QTVRRSPSADQSLEDSPSKV 452
           F+ D     +P +K+     +   P         S      +VR+SP+    LE S    
Sbjct: 296 FKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL---LEVSMPHF 352

Query: 453 PKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI 512
            ++ SF                    +E+  L GE ++     P   +++ L    + +I
Sbjct: 353 MRTNSF--------------------AEDLDLEGETLL----TPITHISQ-LREHHRATI 387

Query: 513 RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGP--- 569
           + +  M++ V+K+KF+++ +PYDV DVIEQYS GHL+++ RIK LQ R+DQ +G+     
Sbjct: 388 KVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFI 447

Query: 570 AITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGI 622
           ++++K + +G          ++  RL +VE +V  ++++L  + ++  Q + +
Sbjct: 448 SVSEKSKDRG--------SNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSL 492


>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2a [Homo sapiens]
          Length = 613

 Score =  104 bits (260), Expect = 3e-22
 Identities = 77/292 (26%), Positives = 137/292 (46%), Gaps = 44/292 (15%)

Query: 62  AGAGKPPKRNAFYRKLQNFLYNVLERP---RGWAFIYHAYVFLLVFS----CL------- 107
           AG G P  ++  +R+LQ  ++ + E P   R   FI  A +F ++ S    CL       
Sbjct: 196 AGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFN 255

Query: 108 --------VLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
                   V++  S + +YE  ++ AL  +E V +V F  E+ VRI  +           
Sbjct: 256 IVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSP---------N 306

Query: 160 RLKFARKPFCVIDIMVLIA---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGG 216
           +L+F +    +ID + ++     + +    S+        LR +RF++ILR+ ++ R   
Sbjct: 307 KLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFV 366

Query: 217 TWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEK----------GENDHFDTYAD 266
             ++LG  + A + E +       L +++ + ++Y AE+           E+  F     
Sbjct: 367 GLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPI 426

Query: 267 ALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
             WW ++T+TT+GYGD YPQTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 427 GFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2b [Homo sapiens]
          Length = 638

 Score =  104 bits (260), Expect = 3e-22
 Identities = 77/292 (26%), Positives = 137/292 (46%), Gaps = 44/292 (15%)

Query: 62  AGAGKPPKRNAFYRKLQNFLYNVLERP---RGWAFIYHAYVFLLVFS----CL------- 107
           AG G P  ++  +R+LQ  ++ + E P   R   FI  A +F ++ S    CL       
Sbjct: 196 AGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFN 255

Query: 108 --------VLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
                   V++  S + +YE  ++ AL  +E V +V F  E+ VRI  +           
Sbjct: 256 IVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSP---------N 306

Query: 160 RLKFARKPFCVIDIMVLIA---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGG 216
           +L+F +    +ID + ++     + +    S+        LR +RF++ILR+ ++ R   
Sbjct: 307 KLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFV 366

Query: 217 TWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEK----------GENDHFDTYAD 266
             ++LG  + A + E +       L +++ + ++Y AE+           E+  F     
Sbjct: 367 GLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPI 426

Query: 267 ALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
             WW ++T+TT+GYGD YPQTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 427 GFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2c [Homo sapiens]
          Length = 558

 Score =  104 bits (260), Expect = 3e-22
 Identities = 77/292 (26%), Positives = 137/292 (46%), Gaps = 44/292 (15%)

Query: 62  AGAGKPPKRNAFYRKLQNFLYNVLERP---RGWAFIYHAYVFLLVFS----CL------- 107
           AG G P  ++  +R+LQ  ++ + E P   R   FI  A +F ++ S    CL       
Sbjct: 196 AGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFN 255

Query: 108 --------VLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
                   V++  S + +YE  ++ AL  +E V +V F  E+ VRI  +           
Sbjct: 256 IVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSP---------N 306

Query: 160 RLKFARKPFCVIDIMVLIA---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGG 216
           +L+F +    +ID + ++     + +    S+        LR +RF++ILR+ ++ R   
Sbjct: 307 KLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFV 366

Query: 217 TWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEK----------GENDHFDTYAD 266
             ++LG  + A + E +       L +++ + ++Y AE+           E+  F     
Sbjct: 367 GLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPI 426

Query: 267 ALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
             WW ++T+TT+GYGD YPQTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 427 GFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|119395748 potassium voltage-gated channel subfamily A member 1
           [Homo sapiens]
          Length = 495

 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 61/199 (30%), Positives = 99/199 (49%), Gaps = 18/199 (9%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAA- 185
           +I+E + I+ F  E  VR +A            +  F +     IDI+ +I     L   
Sbjct: 222 FIVETLCIIWFSFELVVRFFACP---------SKTDFFKNIMNFIDIVAIIPYFITLGTE 272

Query: 186 -----GSQGNVFATSA--LRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYI 238
                G+Q    ATS   LR +R +++ R+ ++ R     ++LG  + A  +EL    + 
Sbjct: 273 IAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFF 332

Query: 239 GFLCLILASFLVYLAEKGEND-HFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATF 297
            F+ +IL S  VY AE  E + HF +  DA WW ++++TT+GYGD YP T  G+++ +  
Sbjct: 333 LFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLC 392

Query: 298 TLIGVSFFALPAGILGSGF 316
            + GV   ALP  ++ S F
Sbjct: 393 AIAGVLTIALPVPVIVSNF 411


>gi|88758565 potassium voltage-gated channel, shaker-related
           subfamily, member 3 [Homo sapiens]
          Length = 575

 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 58/197 (29%), Positives = 99/197 (50%), Gaps = 16/197 (8%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLA-- 184
           +++E + I+ F  E  VR +A            +  F+R    +IDI+ +I     L   
Sbjct: 296 FVVETLCIIWFSFELLVRFFACP---------SKATFSRNIMNLIDIVAIIPYFITLGTE 346

Query: 185 -AGSQGN---VFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
            A  QGN     + + LR +R +++ R+ ++ R     ++LG  + A  +EL    +  F
Sbjct: 347 LAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF 406

Query: 241 LCLILASFLVYLAEKGE-NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTL 299
           + +IL S  VY AE  +    F +  DA WW ++T+TT+GYGD +P T  G+++ +   +
Sbjct: 407 IGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAI 466

Query: 300 IGVSFFALPAGILGSGF 316
            GV   ALP  ++ S F
Sbjct: 467 AGVLTIALPVPVIVSNF 483


>gi|4504817 potassium voltage-gated channel, shaker-related
           subfamily, member 4 [Homo sapiens]
          Length = 653

 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 59/201 (29%), Positives = 97/201 (48%), Gaps = 20/201 (9%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAA- 185
           +I+E V IV F  E+ VR +A            +  F +    +IDI+ ++     L   
Sbjct: 372 FIVETVCIVWFSFEFVVRCFACP---------SQALFFKNIMNIIDIVSILPYFITLGTD 422

Query: 186 ---------GSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAW 236
                    G Q    + + LR +R +++ R+ ++ R     ++LG  + A  +EL    
Sbjct: 423 LAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLI 482

Query: 237 YIGFLCLILASFLVYLAEKGE-NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAA 295
           +  F+ +IL S  VY AE  E   HF +  DA WW ++T+TT+GYGD  P T  G+++ +
Sbjct: 483 FFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGS 542

Query: 296 TFTLIGVSFFALPAGILGSGF 316
              + GV   ALP  ++ S F
Sbjct: 543 LCAIAGVLTIALPVPVIVSNF 563


>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
           member 1 [Homo sapiens]
          Length = 858

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 73/268 (27%), Positives = 132/268 (49%), Gaps = 24/268 (8%)

Query: 81  LYNVLERPRGWA---FIYHAYVFLLVFSCLVLSV-----FSTIKEYEKSSEGA-LYILEI 131
           L+++LE+P        +    +  +V S + LS+       ++ E+ +S++   L  +E 
Sbjct: 175 LWDLLEKPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEA 234

Query: 132 VTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIAS-IAVLAAGSQGN 190
           V I  F +EY +R  ++      + W    KF + P   ID++ ++   + +    S  +
Sbjct: 235 VCIAWFTMEYLLRFLSSP-----KKW----KFFKGPLNAIDLLAILPYYVTIFLTESNKS 285

Query: 191 VFATSALRSL----RFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILA 246
           V     +R +    R ++ILR++++ R     + LG  +     EL        + +++ 
Sbjct: 286 VLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIF 345

Query: 247 SFLVYLAEKGEND-HFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFF 305
           S LV+ AEK E+D  F +   + WW  IT+TT+GYGD YP+T  G+++     + GV   
Sbjct: 346 SSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVI 405

Query: 306 ALPAGILGSGFALKVQEQHRQKHFEKRR 333
           ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 406 ALPIPIIVNNFSEFYKEQKRQEKAIKRR 433


>gi|27436974 potassium voltage-gated channel, Shab-related
           subfamily, member 2 [Homo sapiens]
          Length = 911

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 73/269 (27%), Positives = 131/269 (48%), Gaps = 26/269 (9%)

Query: 81  LYNVLERPRGWA---FIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGA-------LYILE 130
           L+++LE+P        +    +  +V S + LS+ +T+ E +++ E         L  +E
Sbjct: 179 LWDLLEKPNSSVAAKILAIVSILFIVLSTIALSL-NTLPELQETDEFGQLNDNRQLAHVE 237

Query: 131 IVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIAS-IAVLAAGSQG 189
            V I  F +EY +R  ++           + KF + P  VID++ ++   + +    S  
Sbjct: 238 AVCIAWFTMEYLLRFLSSP---------NKWKFFKGPLNVIDLLAILPYYVTIFLTESNK 288

Query: 190 NVFATSALRSL----RFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLIL 245
           +V     +R +    R ++ILR++++ R     + LG  +     EL        + +++
Sbjct: 289 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 348

Query: 246 ASFLVYLAEKGEN-DHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSF 304
            S LV+ AEK E+   F +   + WW  IT+TT+GYGD YP+T  G+++     + GV  
Sbjct: 349 FSSLVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLV 408

Query: 305 FALPAGILGSGFALKVQEQHRQKHFEKRR 333
            ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 409 IALPIPIIVNNFSEFYKEQKRQEKAIKRR 437


>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
           isoform B [Homo sapiens]
          Length = 511

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 55/213 (25%), Positives = 102/213 (47%), Gaps = 22/213 (10%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V +V F  E+ +R+              +++F +    +ID + ++ 
Sbjct: 238 EAETEAFLTYIEGVCVVWFTFEFLMRVIFCP---------NKVEFIKNSLNIIDFVAILP 288

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 289 FYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 348

Query: 236 WYIGFLCLILASFLVYLAEK----------GENDHFDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+           E+ HF       WW ++T+TT+GYGD YP
Sbjct: 349 IIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYP 408

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
           QTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 409 QTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 441


>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
           isoform A [Homo sapiens]
          Length = 585

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 55/213 (25%), Positives = 102/213 (47%), Gaps = 22/213 (10%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V +V F  E+ +R+              +++F +    +ID + ++ 
Sbjct: 238 EAETEAFLTYIEGVCVVWFTFEFLMRVIFCP---------NKVEFIKNSLNIIDFVAILP 288

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 289 FYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 348

Query: 236 WYIGFLCLILASFLVYLAEK----------GENDHFDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+           E+ HF       WW ++T+TT+GYGD YP
Sbjct: 349 IIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYP 408

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
           QTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 409 QTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 441


>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
           isoform c [Homo sapiens]
          Length = 626

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 61/228 (26%), Positives = 108/228 (47%), Gaps = 22/228 (9%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V ++ F +E+ VRI     CC        L F +    +ID + ++ 
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILP 324

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 325 FYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384

Query: 236 WYIGFLCLILASFLVYLAEK--------GENDH--FDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+          NDH  F       WW ++T+TT+GYGD YP
Sbjct: 385 IIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYP 444

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRR 333
           +TW+G L+ A   L GV   A+P  ++ + F +       ++   K+R
Sbjct: 445 KTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
           isoform a [Homo sapiens]
          Length = 635

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 61/228 (26%), Positives = 108/228 (47%), Gaps = 22/228 (9%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V ++ F +E+ VRI     CC        L F +    +ID + ++ 
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILP 324

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 325 FYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384

Query: 236 WYIGFLCLILASFLVYLAEK--------GENDH--FDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+          NDH  F       WW ++T+TT+GYGD YP
Sbjct: 385 IIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYP 444

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRR 333
           +TW+G L+ A   L GV   A+P  ++ + F +       ++   K+R
Sbjct: 445 KTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
           isoform b [Homo sapiens]
          Length = 582

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 61/228 (26%), Positives = 108/228 (47%), Gaps = 22/228 (9%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V ++ F +E+ VRI     CC        L F +    +ID + ++ 
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILP 324

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 325 FYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384

Query: 236 WYIGFLCLILASFLVYLAEK--------GENDH--FDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+          NDH  F       WW ++T+TT+GYGD YP
Sbjct: 385 IIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYP 444

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRR 333
           +TW+G L+ A   L GV   A+P  ++ + F +       ++   K+R
Sbjct: 445 KTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|4504821 potassium voltage-gated channel, shaker-related
           subfamily, member 6 [Homo sapiens]
          Length = 529

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 58/207 (28%), Positives = 98/207 (47%), Gaps = 26/207 (12%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVL--- 183
           +++E + IV F  E  VR  A            +  F R    +ID++ +      L   
Sbjct: 264 FLVETLCIVWFTFELLVRFSACP---------SKPAFFRNIMNIIDLVAIFPYFITLGTE 314

Query: 184 ---------AAGSQGN----VFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSK 230
                    A+G  G       + + LR +R +++ R+ ++ R     ++LG  + A  +
Sbjct: 315 LVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMR 374

Query: 231 ELVTAWYIGFLCLILASFLVYLAEKGENDH-FDTYADALWWGLITLTTIGYGDKYPQTWN 289
           EL    +  F+ +IL S  VY AE  ++D  F +  DA WW ++T+TT+GYGD YP T  
Sbjct: 375 ELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVG 434

Query: 290 GRLLAATFTLIGVSFFALPAGILGSGF 316
           G+++ +   + GV   ALP  ++ S F
Sbjct: 435 GKIVGSLCAIAGVLTIALPVPVIVSNF 461


>gi|4826782 potassium voltage-gated channel, shaker-related
           subfamily, member 2 [Homo sapiens]
          Length = 499

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 56/200 (28%), Positives = 96/200 (48%), Gaps = 19/200 (9%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAA- 185
           +I+E + I+ F  E+ VR +A            +  F      +IDI+ +I     L   
Sbjct: 223 FIVETLCIIWFSFEFLVRFFACP---------SKAGFFTNIMNIIDIVAIIPYFITLGTE 273

Query: 186 -------GSQGN-VFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWY 237
                    QG    + + LR +R +++ R+ ++ R     ++LG  + A  +EL    +
Sbjct: 274 LAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIF 333

Query: 238 IGFLCLILASFLVYLAEKGEND-HFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAAT 296
             F+ +IL S  VY AE  E +  F +  DA WW ++++TT+GYGD  P T  G+++ + 
Sbjct: 334 FLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSL 393

Query: 297 FTLIGVSFFALPAGILGSGF 316
             + GV   ALP  ++ S F
Sbjct: 394 CAIAGVLTIALPVPVIVSNF 413


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,739,598
Number of Sequences: 37866
Number of extensions: 1982291
Number of successful extensions: 9260
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 148
Number of HSP's that attempted gapping in prelim test: 8682
Number of HSP's gapped (non-prelim): 622
length of query: 844
length of database: 18,247,518
effective HSP length: 111
effective length of query: 733
effective length of database: 14,044,392
effective search space: 10294539336
effective search space used: 10294539336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.