Guide to the Human Genome
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Name: PLK1 Sequence: fasta or formatted (603aa) NCBI GI: 21359873
Description:

polo-like kinase 1

Referenced in:

Centrosome
Additional Serine / Threonine Protein Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6         40           3
 C cysteine            2.2         13           2
 D aspartate           4.8         29           1
 E glutamate           7.0         42           2
 F phenylalanine       3.8         23           2
 G glycine             5.6         34           2
 H histidine           2.7         16           1
 I isoleucine          5.1         31           2
 K lysine              6.6         40           2
 L leucine            11.8         71           3
 M methionine          1.7         10           1
 N asparagine          3.6         22           1
 P proline             6.3         38           2
 Q glutamine           2.2         13           2
 R arginine            7.6         46           3
 S serine              7.1         43           2
 T threonine           4.6         28           1
 V valine              6.1         37           2
 W tryptophan          0.7          4           1
 Y tyrosine            3.8         23           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   polo-like kinase 1 
PLK3                  0.362   polo-like kinase 3 
PLK2                  0.354   polo-like kinase 2 
PLK4                  0.151   polo-like kinase 4 
AURKA                 0.116   serine/threonine protein kinase 6 
AURKA                 0.116   serine/threonine protein kinase 6 
AURKA                 0.116   serine/threonine protein kinase 6 
AURKA                 0.116   serine/threonine protein kinase 6 
AURKA                 0.116   serine/threonine protein kinase 6 
AURKA                 0.116   serine/threonine protein kinase 6 
STK33                 0.116   serine/threonine kinase 33 
HUNK                  0.113   hormonally upregulated Neu-associated kinase 
NUAK1                 0.111   AMPK-related protein kinase 5 
MARK3                 0.105   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.105   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.105   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.105   MAP/microtubule affinity-regulating kinase 3 isoform...
MARK2                 0.103   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.103   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.103   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.103   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.103   MAP/microtubule affinity-regulating kinase 2 isoform...
MARK1                 0.103   MAP/microtubule affinity-regulating kinase 1 
MARK4                 0.103   MAP/microtubule affinity-regulating kinase 4 
NUAK2                 0.102   NUAK family, SNF1-like kinase, 2 
RPS6KA3               0.101   ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Ho...
PRKAA1                0.101   protein kinase, AMP-activated, alpha 1 catalytic sub...
PDPK1                 0.101   3-phosphoinositide dependent protein kinase-1 isoform...
LOC100287510          0.101   PREDICTED: hypothetical protein XP_002343452 
PRKG2                 0.100   protein kinase, cGMP-dependent, type II 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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