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Search of human proteins with 120587019
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|120587019 zinc finger protein 318 [Homo sapiens]
(2279 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|120587019 zinc finger protein 318 [Homo sapiens] 4557 0.0
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 73 3e-12
gi|210032580 SET domain containing 1B [Homo sapiens] 67 2e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 66 4e-10
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 64 2e-09
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 64 2e-09
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 64 2e-09
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 64 2e-09
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 64 2e-09
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 64 2e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 62 6e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 62 6e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is... 62 6e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 62 6e-09
gi|221219020 NYD-SP11 protein [Homo sapiens] 62 8e-09
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi... 60 2e-08
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi... 60 2e-08
gi|40807465 zinc finger protein 341 [Homo sapiens] 59 4e-08
gi|87299628 biorientation of chromosomes in cell division 1-like... 59 5e-08
gi|116256475 zinc finger protein 827 [Homo sapiens] 59 7e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 58 1e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 58 1e-07
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 57 2e-07
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 57 2e-07
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 57 2e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 57 2e-07
gi|150378539 piccolo isoform 1 [Homo sapiens] 57 2e-07
gi|52485606 formin-like 2 [Homo sapiens] 57 3e-07
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 57 3e-07
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 57 3e-07
>gi|120587019 zinc finger protein 318 [Homo sapiens]
Length = 2279
Score = 4557 bits (11820), Expect = 0.0
Identities = 2279/2279 (100%), Positives = 2279/2279 (100%)
Query: 1 MYRSSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSP 60
MYRSSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSP
Sbjct: 1 MYRSSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSP 60
Query: 61 SGHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRLFPPGPAGFRGSSRGESRADYAR 120
SGHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRLFPPGPAGFRGSSRGESRADYAR
Sbjct: 61 SGHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRLFPPGPAGFRGSSRGESRADYAR 120
Query: 121 DGRGDHPGDSGSRRRSPGLCSDSLEKSLRITVGNDHFCVSTPERRRLSDRLGSPVDNLED 180
DGRGDHPGDSGSRRRSPGLCSDSLEKSLRITVGNDHFCVSTPERRRLSDRLGSPVDNLED
Sbjct: 121 DGRGDHPGDSGSRRRSPGLCSDSLEKSLRITVGNDHFCVSTPERRRLSDRLGSPVDNLED 180
Query: 181 MDRDDLTDDSVFTRSSQCSRGLERYISQEEGPLSPFLGQLDEDYRTKETFLHRSDYSPHI 240
MDRDDLTDDSVFTRSSQCSRGLERYISQEEGPLSPFLGQLDEDYRTKETFLHRSDYSPHI
Sbjct: 181 MDRDDLTDDSVFTRSSQCSRGLERYISQEEGPLSPFLGQLDEDYRTKETFLHRSDYSPHI 240
Query: 241 SCHDELLRGTERNREKLKGYSIRSEERSREAKRPRYDDTVKINSMGGDHPSFTSGTRNYR 300
SCHDELLRGTERNREKLKGYSIRSEERSREAKRPRYDDTVKINSMGGDHPSFTSGTRNYR
Sbjct: 241 SCHDELLRGTERNREKLKGYSIRSEERSREAKRPRYDDTVKINSMGGDHPSFTSGTRNYR 300
Query: 301 QRRRSPSPRFLDPEFRELDLARRKREEEEERSRSLSQELVGVDGGGTGCSIPGLSGVLTA 360
QRRRSPSPRFLDPEFRELDLARRKREEEEERSRSLSQELVGVDGGGTGCSIPGLSGVLTA
Sbjct: 301 QRRRSPSPRFLDPEFRELDLARRKREEEEERSRSLSQELVGVDGGGTGCSIPGLSGVLTA 360
Query: 361 SEPGYSLHRPEEVSVMPKKSILKKRIEVDIMEPSMQLESFSSSTSSSQDHPLYSGHPSLP 420
SEPGYSLHRPEEVSVMPKKSILKKRIEVDIMEPSMQLESFSSSTSSSQDHPLYSGHPSLP
Sbjct: 361 SEPGYSLHRPEEVSVMPKKSILKKRIEVDIMEPSMQLESFSSSTSSSQDHPLYSGHPSLP 420
Query: 421 LSGAIAAFASEIENKGTMVETALKEPQGNLYQWGPLPGIPKDNSPLREKFGSFLCHKDNL 480
LSGAIAAFASEIENKGTMVETALKEPQGNLYQWGPLPGIPKDNSPLREKFGSFLCHKDNL
Sbjct: 421 LSGAIAAFASEIENKGTMVETALKEPQGNLYQWGPLPGIPKDNSPLREKFGSFLCHKDNL 480
Query: 481 DLKAEGPERHTDFLLPHERASQDGSGFSRILSMLADSTSTQEKRRRSFPDIEDEEKFLYG 540
DLKAEGPERHTDFLLPHERASQDGSGFSRILSMLADSTSTQEKRRRSFPDIEDEEKFLYG
Sbjct: 481 DLKAEGPERHTDFLLPHERASQDGSGFSRILSMLADSTSTQEKRRRSFPDIEDEEKFLYG 540
Query: 541 DEEEDLKAESVPKPLGSSESEVMRQKASSLPSSAPAVKLESLEETNPEYAKIHDLLKTIG 600
DEEEDLKAESVPKPLGSSESEVMRQKASSLPSSAPAVKLESLEETNPEYAKIHDLLKTIG
Sbjct: 541 DEEEDLKAESVPKPLGSSESEVMRQKASSLPSSAPAVKLESLEETNPEYAKIHDLLKTIG 600
Query: 601 LDIGVAEISQLAARTQERLHGKKPSLRSSADRRSSVDRYFSADHCSSVDHRFSADRCSSV 660
LDIGVAEISQLAARTQERLHGKKPSLRSSADRRSSVDRYFSADHCSSVDHRFSADRCSSV
Sbjct: 601 LDIGVAEISQLAARTQERLHGKKPSLRSSADRRSSVDRYFSADHCSSVDHRFSADRCSSV 660
Query: 661 DHCFSADRRSSDPHRLESREAHHSNTHSPEVSHPHPPSPVDPYLLTKNSPPFLKSDHPVG 720
DHCFSADRRSSDPHRLESREAHHSNTHSPEVSHPHPPSPVDPYLLTKNSPPFLKSDHPVG
Sbjct: 661 DHCFSADRRSSDPHRLESREAHHSNTHSPEVSHPHPPSPVDPYLLTKNSPPFLKSDHPVG 720
Query: 721 HISGPEVVGSGFQSSVAVRCMLPSAPSAPIRLPHTAALSQFHMPRASQFAAARIPPNYQG 780
HISGPEVVGSGFQSSVAVRCMLPSAPSAPIRLPHTAALSQFHMPRASQFAAARIPPNYQG
Sbjct: 721 HISGPEVVGSGFQSSVAVRCMLPSAPSAPIRLPHTAALSQFHMPRASQFAAARIPPNYQG 780
Query: 781 PAIPPASFDAYRHYMAYAASRWPMYPTSQPSNHPVPEPHRIMPITKQATRSRPNLRVIPT 840
PAIPPASFDAYRHYMAYAASRWPMYPTSQPSNHPVPEPHRIMPITKQATRSRPNLRVIPT
Sbjct: 781 PAIPPASFDAYRHYMAYAASRWPMYPTSQPSNHPVPEPHRIMPITKQATRSRPNLRVIPT 840
Query: 841 VTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKN 900
VTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKN
Sbjct: 841 VTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKN 900
Query: 901 DREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELR 960
DREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELR
Sbjct: 901 DREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELR 960
Query: 961 QEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNS 1020
QEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNS
Sbjct: 961 QEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNS 1020
Query: 1021 SSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFD 1080
SSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFD
Sbjct: 1021 SSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFD 1080
Query: 1081 FFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQL 1140
FFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQL
Sbjct: 1081 FFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQL 1140
Query: 1141 CEEFLGDPISGEQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSEL 1200
CEEFLGDPISGEQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSEL
Sbjct: 1141 CEEFLGDPISGEQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSEL 1200
Query: 1201 KRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLK 1260
KRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLK
Sbjct: 1201 KRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLK 1260
Query: 1261 EEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPI 1320
EEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPI
Sbjct: 1261 EEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPI 1320
Query: 1321 KIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIK 1380
KIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIK
Sbjct: 1321 KIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIK 1380
Query: 1381 SSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQI 1440
SSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQI
Sbjct: 1381 SSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQI 1440
Query: 1441 LPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVL 1500
LPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVL
Sbjct: 1441 LPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVL 1500
Query: 1501 PVAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCL 1560
PVAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCL
Sbjct: 1501 PVAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCL 1560
Query: 1561 ATANAKDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKSSDTSSTSPLNS 1620
ATANAKDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKSSDTSSTSPLNS
Sbjct: 1561 ATANAKDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKSSDTSSTSPLNS 1620
Query: 1621 SASQEELHQDEGLVAAPIVSNSEKPIAKTLVALGKWSVVEHVGPKSTGSTYGFLQPLTRL 1680
SASQEELHQDEGLVAAPIVSNSEKPIAKTLVALGKWSVVEHVGPKSTGSTYGFLQPLTRL
Sbjct: 1621 SASQEELHQDEGLVAAPIVSNSEKPIAKTLVALGKWSVVEHVGPKSTGSTYGFLQPLTRL 1680
Query: 1681 CQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSELDLGEPGPPGVEPPPQLLDIQC 1740
CQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSELDLGEPGPPGVEPPPQLLDIQC
Sbjct: 1681 CQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSELDLGEPGPPGVEPPPQLLDIQC 1740
Query: 1741 KESQKLVEIHLRESVNQDKESQELRKSEDCRESEIETNTELKERVKELSEGIVDEGVSTS 1800
KESQKLVEIHLRESVNQDKESQELRKSEDCRESEIETNTELKERVKELSEGIVDEGVSTS
Sbjct: 1741 KESQKLVEIHLRESVNQDKESQELRKSEDCRESEIETNTELKERVKELSEGIVDEGVSTS 1800
Query: 1801 IGPHSIDDSNLNHGNRYMWEGEVKQPNLLMIDKEAEQSNKLMTGSETPSKVVIKLSPQAC 1860
IGPHSIDDSNLNHGNRYMWEGEVKQPNLLMIDKEAEQSNKLMTGSETPSKVVIKLSPQAC
Sbjct: 1801 IGPHSIDDSNLNHGNRYMWEGEVKQPNLLMIDKEAEQSNKLMTGSETPSKVVIKLSPQAC 1860
Query: 1861 SFTKAKLDSFLSEARSLLNPQDTPVKISAPELLLHSPARSAMCLTGSPQEQGVSVVSEEG 1920
SFTKAKLDSFLSEARSLLNPQDTPVKISAPELLLHSPARSAMCLTGSPQEQGVSVVSEEG
Sbjct: 1861 SFTKAKLDSFLSEARSLLNPQDTPVKISAPELLLHSPARSAMCLTGSPQEQGVSVVSEEG 1920
Query: 1921 LENSAPESASRTSRYRSLKLKRERSKDFQVKKIYELAVWDENKKRPETWESPEKPKTEAL 1980
LENSAPESASRTSRYRSLKLKRERSKDFQVKKIYELAVWDENKKRPETWESPEKPKTEAL
Sbjct: 1921 LENSAPESASRTSRYRSLKLKRERSKDFQVKKIYELAVWDENKKRPETWESPEKPKTEAL 1980
Query: 1981 ELQDVHPELTVTIESKALEDFEATDLKVEELTALGNLGDMPVDFCTTRVSPAHRSPTVLC 2040
ELQDVHPELTVTIESKALEDFEATDLKVEELTALGNLGDMPVDFCTTRVSPAHRSPTVLC
Sbjct: 1981 ELQDVHPELTVTIESKALEDFEATDLKVEELTALGNLGDMPVDFCTTRVSPAHRSPTVLC 2040
Query: 2041 QKVCEENSVSPIGCNSSDPADFEPIPSFSGFPLDSPKTLVLDFETEGERNSPNPRSVRIP 2100
QKVCEENSVSPIGCNSSDPADFEPIPSFSGFPLDSPKTLVLDFETEGERNSPNPRSVRIP
Sbjct: 2041 QKVCEENSVSPIGCNSSDPADFEPIPSFSGFPLDSPKTLVLDFETEGERNSPNPRSVRIP 2100
Query: 2101 SPNILKTGLTENVDRGLGGLEGTHQALDLLAGGMMPEEVKESSQLDKQESLGLELKTINS 2160
SPNILKTGLTENVDRGLGGLEGTHQALDLLAGGMMPEEVKESSQLDKQESLGLELKTINS
Sbjct: 2101 SPNILKTGLTENVDRGLGGLEGTHQALDLLAGGMMPEEVKESSQLDKQESLGLELKTINS 2160
Query: 2161 AGLGPSPCLPDLVDFVTRTSGVQKDKLCSPLSEPGDPSKCSSLELGPLQLEISNASTTEV 2220
AGLGPSPCLPDLVDFVTRTSGVQKDKLCSPLSEPGDPSKCSSLELGPLQLEISNASTTEV
Sbjct: 2161 AGLGPSPCLPDLVDFVTRTSGVQKDKLCSPLSEPGDPSKCSSLELGPLQLEISNASTTEV 2220
Query: 2221 AILQVDDDSGDPLNLVKAPVSRSPPREQVIEDNMVPQGMPEQETTVGAIQDHTESSVHN 2279
AILQVDDDSGDPLNLVKAPVSRSPPREQVIEDNMVPQGMPEQETTVGAIQDHTESSVHN
Sbjct: 2221 AILQVDDDSGDPLNLVKAPVSRSPPREQVIEDNMVPQGMPEQETTVGAIQDHTESSVHN 2279
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 73.2 bits (178), Expect = 3e-12
Identities = 94/409 (22%), Positives = 158/409 (38%), Gaps = 44/409 (10%)
Query: 1176 ERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLED 1235
E R A L L+ + + L + KPK+++K+KK K ++ K ++V E +
Sbjct: 504 EEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKS 563
Query: 1236 QLSEGRNSPEKAENKRNTGIKLQLKEEVKKESPTSSSFGKFSWKKPEKEEEKS--SLVTP 1293
+ E K N N+ + + +K + P + + KP EEK SL
Sbjct: 564 KAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDIN 623
Query: 1294 SISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLP 1353
+ E++ + + + P +I++ +T+ T + TS K R
Sbjct: 624 KLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA 683
Query: 1354 IPSTVLRKSCSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFGGE 1413
V+ S + + F S +S ++ ++S ++ P K G
Sbjct: 684 EKVDVIAGS--------SKMKGFSSSESESSSESSSSDSEDSETEMA--PKSKKKGHPGR 733
Query: 1414 EVILKGSPEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPP-----PPPVIPHPAAPSAAQ 1468
E + + + P+ +P+Q PPP PPPPPPP PPP P P+ P A
Sbjct: 734 EQKKHHHHHHQQM---QQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQA- 789
Query: 1469 ANAILAP-VKSNPVVSQTLSPGFVGPN--ILNPVLPVAIMAS----AQPAA-IPSDETAP 1520
AP +KS+P P F+ +L P LP ++ QP +P E P
Sbjct: 790 -----APAMKSSP-------PPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPP 837
Query: 1521 GVSESDRDQT---LFSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAK 1566
+ + T L V PP L + +Q + R + L A+
Sbjct: 838 HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPAR 886
Score = 42.4 bits (98), Expect = 0.005
Identities = 36/123 (29%), Positives = 47/123 (38%), Gaps = 16/123 (13%)
Query: 1436 LPEQILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVV---SQTLSPGFVG 1492
+P Q L PPP PP P PPP P P A PVK+ V + T +P +
Sbjct: 242 VPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTID 301
Query: 1493 PNILNPVLP----VAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSE 1548
P P LP + + ++ P V +S + P P SS SE
Sbjct: 302 PIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQ---------HPAPEKSSKVSE 352
Query: 1549 QAK 1551
Q K
Sbjct: 353 QLK 355
Score = 38.1 bits (87), Expect = 0.100
Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 2/34 (5%)
Query: 1433 PSH--LPEQILPPPPPPPPPPPPPPPVIPHPAAP 1464
P H + +Q+ PPPPPPP P PPP H P
Sbjct: 961 PPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPP 994
Score = 37.7 bits (86), Expect = 0.13
Identities = 80/399 (20%), Positives = 131/399 (32%), Gaps = 72/399 (18%)
Query: 539 YGDEEEDLKAESVPKPLGSSESEVMRQKASSLPSSAPAVKLE-------SLEETNPEYAK 591
Y EEED KP+ E + + LP + SL+ +NP+ +
Sbjct: 599 YESEEEDKC-----KPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIE 653
Query: 592 IH-DLLKTIGLDIGVAEISQLAARTQERLHGKKPSLRSSAD--RRSSVDRYFSADHCSSV 648
I + LK + + +L L K+ D SS + FS+ S
Sbjct: 654 IDFETLKP-------STLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESS 706
Query: 649 DHRFSADRCSSVDHCFSADRRSSDPHRLESREAHHSNTHSPEVSHPHPPSPVDPYLLTKN 708
S+D S ++ P R + + HH + + P P P P
Sbjct: 707 SESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPP 766
Query: 709 SPPFLKSDHPVGHISGPEVVGSGFQSSVAVRCMLPSAPSAPIRLPHTAALSQFHMPRASQ 768
PP + P P P +P AA + P
Sbjct: 767 PPPPQQQQQ-------------------------PPPPPPPPSMPQQAAPAMKSSP--PP 799
Query: 769 FAAARIPPNYQGPAIPPASFDAYRHYMAYAASRWPMYPTSQPS---NHPVPEPHRIMP-I 824
F A ++P P +P + FD H+ P+ QP + P P H P +
Sbjct: 800 FIATQVP--VLEPQLPGSVFDPIGHFTQ------PILHLPQPELPPHLPQPPEHSTPPHL 851
Query: 825 TKQATRSRPNLRVIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNR 884
+ A S P L P +P + + ++P P+L + + +
Sbjct: 852 NQHAVVSPPALH---NALPQQPSRPSNRAAALPPKPARPPAVSPALTQ---TPLLPQPPM 905
Query: 885 ASQKQKVIEEREKLKNDREARQKKMYYLRTELERLHKQQ 923
A Q ++E+ E + Q ++Y L++L K Q
Sbjct: 906 AQPPQVLLEDEEPPAPPLTSMQMQLY-----LQQLQKVQ 939
Score = 34.7 bits (78), Expect = 1.1
Identities = 21/62 (33%), Positives = 23/62 (37%), Gaps = 12/62 (19%)
Query: 1436 LPEQILPPPPPPPPPPP------------PPPPVIPHPAAPSAAQANAILAPVKSNPVVS 1483
LP + PPPP PPP PPPP P P P Q PV P+
Sbjct: 945 LPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQF 1004
Query: 1484 QT 1485
T
Sbjct: 1005 ST 1006
Score = 34.7 bits (78), Expect = 1.1
Identities = 24/82 (29%), Positives = 26/82 (31%), Gaps = 24/82 (29%)
Query: 1431 SEPSHLPEQILPPPPPPPPPPP------------------------PPPPVIPHPAAPSA 1466
S L +Q PPPPP P PPP PPPP P P
Sbjct: 965 SVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP 1024
Query: 1467 AQANAILAPVKSNPVVSQTLSP 1488
Q P K V+ SP
Sbjct: 1025 GQQPPPPQPAKPQQVIQHHHSP 1046
Score = 32.3 bits (72), Expect = 5.5
Identities = 22/88 (25%), Positives = 32/88 (36%)
Query: 16 KDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRG 75
K G S SS SSS + S P P R + H ++ +P
Sbjct: 694 KMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPV 753
Query: 76 RRVSPSPPRARRGSPSPPRGRRLFPPGP 103
+ P PP+ P P + ++ PP P
Sbjct: 754 PQQPPPPPQQPPPPPPPQQQQQPPPPPP 781
Score = 32.3 bits (72), Expect = 5.5
Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 3/67 (4%)
Query: 38 RSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRR 97
+ PPPPP P ++ + P R P P PP+ ++ P PP G++
Sbjct: 971 QQQPPPPPPPQPQPPPQQQHQPPP--RPVHLQPMQFSTHIQQPPPPQGQQ-PPHPPPGQQ 1027
Query: 98 LFPPGPA 104
PP PA
Sbjct: 1028 PPPPQPA 1034
Score = 32.0 bits (71), Expect = 7.1
Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 3/48 (6%)
Query: 1421 PEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPSAAQ 1468
P V L +H+ + PPPP PP PPP P P P+ Q
Sbjct: 993 PPRPVHLQPMQFSTHIQQ---PPPPQGQQPPHPPPGQQPPPPQPAKPQ 1037
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 67.0 bits (162), Expect = 2e-10
Identities = 89/386 (23%), Positives = 145/386 (37%), Gaps = 45/386 (11%)
Query: 1190 LETERRRQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQ---------LSEG 1240
LE + + + K LSE+ + ++E++A+ +E ++DD D+ LSE
Sbjct: 1027 LELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEA 1086
Query: 1241 RNSPEKAENKRNTGIKLQLKEEV--KKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKE 1298
E ++ T + K E ES SS F S P E++ +V ++E
Sbjct: 1087 SEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVV----ARE 1142
Query: 1299 EILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTV 1358
E E +++ + A P + G+ A +P P V + + + I +
Sbjct: 1143 EEEEEEEEEMVAEESMASAGPEDFEQDGEE--AALAPGAPAVDS---LGMEEEVDIETEA 1197
Query: 1359 LRKSCSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILK 1418
+ +M PL + + P + + A LL P + + +
Sbjct: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPE 1257
Query: 1419 GSPEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPPPPPVIP------HPAAPSAAQAN-- 1470
+PE + + E P LP + PP PPP PP PP PP P HP+ P A
Sbjct: 1258 RAPEHDLEV-EPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDH 1316
Query: 1471 --------AILAPVKSNPVVSQT------LSPGFVGPNILNPVLPVAIMASAQPAAIPSD 1516
LA +S V T LS G G ++ +P +P + + PA PS
Sbjct: 1317 PPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGS--PFSYPAPSPSL 1374
Query: 1517 ETAPGVSESDRDQTLFSVLVRPPPPL 1542
+ RD + P PL
Sbjct: 1375 SSGGLPRTPGRDFSFTPTFSEPSGPL 1400
Score = 47.0 bits (110), Expect = 2e-04
Identities = 28/71 (39%), Positives = 31/71 (43%), Gaps = 12/71 (16%)
Query: 1437 PEQILPPPPPPPPPPPP------PPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGF 1490
P PP PPPPPPPPP PPP+ P P P A P + P PG
Sbjct: 683 PPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAH------PAVTVPPPPLPAPPGV 736
Query: 1491 VGPNILNPVLP 1501
P IL P+ P
Sbjct: 737 PPPPILPPLPP 747
Score = 46.6 bits (109), Expect = 3e-04
Identities = 39/126 (30%), Positives = 52/126 (41%), Gaps = 34/126 (26%)
Query: 1346 TKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDI 1405
T + P LP P SC P P+ + G + P + L+ PP
Sbjct: 1455 TPLPPLLPAPLA----SC------PPPMK-----RKPGRPRRSPPSMLSLDGPLVRPP-- 1497
Query: 1406 ISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQI--------LPPPPPP----PPPPPP 1453
A G E ++L G P+ V + +H P + +P PPPP PPPPPP
Sbjct: 1498 AGAALGRELLLLPGQPQTPVFPS-----THDPRTVTLDFRNAGIPAPPPPLPPQPPPPPP 1552
Query: 1454 PPPVIP 1459
PPPV P
Sbjct: 1553 PPPVEP 1558
Score = 38.5 bits (88), Expect = 0.076
Identities = 16/33 (48%), Positives = 19/33 (57%), Gaps = 4/33 (12%)
Query: 1436 LPEQILPPPPPPPPPPP----PPPPVIPHPAAP 1464
+P + PPPPPPPP P PPPP+ P P
Sbjct: 705 MPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVP 737
Score = 37.0 bits (84), Expect = 0.22
Identities = 105/504 (20%), Positives = 173/504 (34%), Gaps = 62/504 (12%)
Query: 1185 GLAVVLETERRRQS-ELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQ------L 1237
GL + L R S ++KRK +K+ + V E+D+ SE+ D+
Sbjct: 948 GLGIGLRGAIRLPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPC 1007
Query: 1238 SEGRNSPEKAENKRNTGIKLQLK---EEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPS 1294
+ P+ +R L+L EE +KES + ++ E+EEE+
Sbjct: 1008 ELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEED--DDD 1065
Query: 1295 ISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPI 1354
++ ES D ED K +TV TS T+S+++
Sbjct: 1066 DDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTS--KAEATSSSESS------- 1116
Query: 1355 PSTVLRKSCSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSA-----DLLLPPDIISKA 1409
S+ S ++ S ++ + + V +ES A D + + A
Sbjct: 1117 ESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALA 1176
Query: 1410 FGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPSAAQA 1469
G V G EE + E P P + PP P P P P +Q
Sbjct: 1177 PGAPAVDSLGMEEEVDIETEAVAPEERPSML--DEPPLPVGVEEPADSREPPEEPGLSQE 1234
Query: 1470 NAIL-------APVKSNPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGV 1522
A+L V++ P +S +P + P P+ + QP P P
Sbjct: 1235 GAMLLSPEPPAKEVEARPPLSPERAPEH--DLEVEPEPPMMLPLPLQPPLPPPRPPRPPS 1292
Query: 1523 SESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGK---- 1578
+ + T S PP PL+ L C + A ++ + + GG+
Sbjct: 1293 PPPEPETTDASHPSVPPEPLAEDHPPHTPGL-----CGSLAKSQSTETVPATPGGEPPLS 1347
Query: 1579 --------------GAPETKGAPETKLSGGPLANGENSNLSRTKSSDTSSTSPLNSSASQ 1624
G+P + AP LS G L + S T + S L
Sbjct: 1348 GGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPL 1407
Query: 1625 EELHQDE--GLVAAPIVSNSEKPI 1646
+DE G +A+P++ + P+
Sbjct: 1408 PTGRRDERSGPLASPVLLETGLPL 1431
Score = 35.8 bits (81), Expect = 0.49
Identities = 15/32 (46%), Positives = 18/32 (56%)
Query: 1433 PSHLPEQILPPPPPPPPPPPPPPPVIPHPAAP 1464
P+H + PPP P PP PPPP + P P P
Sbjct: 718 PAHPAVTVPPPPLPAPPGVPPPPILPPLPPFP 749
Score = 35.0 bits (79), Expect = 0.84
Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 9/101 (8%)
Query: 4 SSARSSVSSHRPKDDGGGGPRSGRSSG-SSSGPARRSSPPPPPSGSSSRTPARRPRSPSG 62
S A+S + P GG P SG SSG S S P SP P+ S S + PR+P
Sbjct: 1326 SLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGR 1385
Query: 63 HRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRLFPPGP 103
+ S P G + P P P GRR GP
Sbjct: 1386 DFSFTPTFSEPSGPLLLPVCPL--------PTGRRDERSGP 1418
Score = 33.5 bits (75), Expect = 2.5
Identities = 73/358 (20%), Positives = 132/358 (36%), Gaps = 55/358 (15%)
Query: 1641 NSEKPIAKTLVA---LGKWSVVEHVGPKSTGSTYGFLQ----PLTRLCQSRPYETITPKT 1693
+ ++P K +A L W E +G + G G P ++ + P +T T
Sbjct: 918 DEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPPDT-TSSG 976
Query: 1694 DTLAIWTSSSF-----QSDTSRDISPEKSELDLGEPGPPGV-----EPPPQLLDIQCKES 1743
D + S+S +S+ RD + +L + P GV P LD +E
Sbjct: 977 DQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEED 1036
Query: 1744 QKLVEIHLRESVNQDKESQELRK--------SEDCRESEIETNTELKERVKELSEGIVDE 1795
+K +ES +++E++E + S+D ESE + E EG DE
Sbjct: 1037 EKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDE 1096
Query: 1796 GVSTSI---------GPHSIDDSNLNHGNRYMWEGEVKQPNLLMIDKEAEQSNKLMTGSE 1846
+ SI S + S + + ++ ++E E+ + M E
Sbjct: 1097 EETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEE 1156
Query: 1847 TPSKV----------VIKLSPQACSFTKAKLDSFLSEARSLLNPQDTPVKISAPELL--L 1894
+ + L+P A + ++ + + P++ P + P L +
Sbjct: 1157 SMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGV 1216
Query: 1895 HSPARSAMCLTGSPQEQGVSVVSEEGLENSAPESASRTSRYR-SLKLKRERSKDFQVK 1951
PA S P+E G +S+EG +PE ++ R L +R D +V+
Sbjct: 1217 EEPADS----REPPEEPG---LSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVE 1267
Score = 32.0 bits (71), Expect = 7.1
Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 10/83 (12%)
Query: 933 EKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQKSL 992
E+DG + L + M++ ++ EA E++ S LD+ +G+ +
Sbjct: 1167 EQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGV-------EEP 1219
Query: 993 SDSREPTEKPGKAEKSK---SPE 1012
+DSREP E+PG +++ SPE
Sbjct: 1220 ADSREPPEEPGLSQEGAMLLSPE 1242
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 65.9 bits (159), Expect = 4e-10
Identities = 126/587 (21%), Positives = 222/587 (37%), Gaps = 90/587 (15%)
Query: 862 PVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKNDREARQKKMYYLRTELERLHK 921
P+ S+P + P + K ++ +K KV+E+ EK + + +TE ++ +
Sbjct: 417 PIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEK--------ETVIVEEQTEETQVTE 468
Query: 922 QQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILG 981
+ E K+ +E++G ++ E ++ + AEEA + E +
Sbjct: 469 EVTEEEEKEAKEEEGKEE----EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVK--- 521
Query: 982 INIFDKSQKSLSDSREPTEKPGKAEKS-KSPEKVSSFSNSSSNKESKVNN-EKFRTKSPK 1039
+ KS ++++ P ++ K+ KSPEK S + + + + EK KSP
Sbjct: 522 -----EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPA 576
Query: 1040 PAESPQSAT----KQLDQPTAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQTLD 1095
+SP+ A ++ P A A + ++ + + +
Sbjct: 577 EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA--------EAKSPVKEEAKS 628
Query: 1096 PYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQLCEEFLGDPISGEQHV 1155
P K +S K++A K +K P K E P + V
Sbjct: 629 PAEVKSPEKAKSPTKEEA-KSPEKAKSPEK-----------------EEAKSPEKAKSPV 670
Query: 1156 KGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEKKEK 1215
K + + K +P+ E ++ ++ ++ + +++ K KEE K
Sbjct: 671 KAEAKSPEKAK----SPVKAEAKSPEKA-------KSPVKEEAKSPEKAKSPVKEEAKSP 719
Query: 1216 KAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKA---ENKRNTGIKL-QLKEEVKKESPTSS 1271
+ KA VKE+ K EK + + E SPEKA E + +K + K K+E+ + +
Sbjct: 720 E-KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778
Query: 1272 SFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKD---KEDGKT---EAGKAKPIKIKLS 1325
K P KEE KS S KE+ K+ KE+ K+ E K + +K+K
Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEP 838
Query: 1326 GKTVVAHTSPWMPVVTTSTQTKIR--PNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSG 1383
K +P P +K P P + + + KP K S
Sbjct: 839 PKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP---------KESK 889
Query: 1384 TTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEK 1430
AK KE + D P +A EV P+EK +A+K
Sbjct: 890 VEAK-----KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK 931
Score = 65.9 bits (159), Expect = 4e-10
Identities = 121/517 (23%), Positives = 203/517 (39%), Gaps = 103/517 (19%)
Query: 842 TPDKPKQ--KESLRGSIPAAQVPV--QVSIPSLIRYNPEKISDEKNRASQKQKVIEEREK 897
+P+K K KE + S P A+ P + P+ ++ +PEK ++ + EK
Sbjct: 546 SPEKAKSPAKEEAK-SPPEAKSPEKEEAKSPAEVK-SPEKAKSPAKEEAKSPAEAKSPEK 603
Query: 898 LKNDREARQKKMYYLRTELERLHKQQGEML---RKKRREKDGHKDPLLVEVSRLQDNIMK 954
K+ + K ++ ++ K E+ + K K+ K P + ++
Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP 663
Query: 955 DIAE--LRQEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKA-----EK 1007
+ A+ ++ EA+ EK +S + A+ +K+ S +E + P KA E+
Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAK--------SPEKAKSPVKEEAKSPEKAKSPVKEE 715
Query: 1008 SKSPEKVSSFSNSSSNKESKVNNE-KFRTKSPKPAESPQSA-TKQLDQPTAAYEYYDAGN 1065
+KSPEK S + K + K KSP+ A+SP+ A T + P A
Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAK-------- 767
Query: 1066 HWCKDCNTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVP-- 1123
+ P ++ + K +S K++ +K +K P
Sbjct: 768 ---------------------TPAKEEARSPADK-FPEKAKSPVKEE-VKSPEKAKSPLK 804
Query: 1124 --AKGSEFLVPISGFYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVDEN----PLYEER 1177
AK E +P +E + P+ E+ + + E KK +E P EE+
Sbjct: 805 EDAKAPEKEIPK--------KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856
Query: 1178 RNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEK----------------KEKKAKAVK 1221
++ ++ A E + + E K EKPKE K EK+A A
Sbjct: 857 KDSKKEE--APKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKV 914
Query: 1222 EVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEVKKESPTSSSFGKFSWKKP 1281
EVKED K EK E E ++ K +K + KE ++ T K +KP
Sbjct: 915 EVKEDAKPKEKTEVAKKEPDDAKAKEPSK-----PAEKKEAAPEKKDTKEEKAKKPEEKP 969
Query: 1282 E-----KEEEKSSLVTPSISKEEILE--SSKDKEDGK 1311
+ KE++K+ PS K E E SS D++D K
Sbjct: 970 KTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSK 1006
Score = 50.1 bits (118), Expect = 3e-05
Identities = 158/815 (19%), Positives = 291/815 (35%), Gaps = 101/815 (12%)
Query: 847 KQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISD-----EKNRASQKQKVIEEREKLKND 901
++ E+ R + +Q L R++ E++ + + + A+Q Q E R+ LK D
Sbjct: 207 QEAEAARVDLQKKAQALQEECGYLRRHHQEEVGELLGQIQGSGAAQAQMQAETRDALKCD 266
Query: 902 REARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQ 961
+ ++ +R +LE G ++ + ++ + V + RL + + +R
Sbjct: 267 VTSALRE---IRAQLE------GHAVQSTLQSEEWFR----VRLDRLSEAAKVNTDAMRS 313
Query: 962 EAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNSS 1021
EE + + +L A+ + ++ SL R E +A+ ++S+ +
Sbjct: 314 AQEEITEYRRQLQ--ARTTELEALKSTKDSLERQRSELEDRHQAD-------IASYQEAI 364
Query: 1022 SNKESKVNNEKFRTKSP-KPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFD 1080
++++ N K+ + + + + LD AAY G ++C G +
Sbjct: 365 QQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEG----EECRIGFGPI-- 418
Query: 1081 FFTHMHNKKHTQTLDPYNRPWA-SKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQ 1139
P++ P K S + +K +KI V K +
Sbjct: 419 ---------------PFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEK----------- 452
Query: 1140 LCEEFLGDPISGEQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSE 1199
E + + + E V E+ K+ +E EE + G ++ ++
Sbjct: 453 --ETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAA 510
Query: 1200 LKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQL 1259
K ++ P +E+ + A+A KE+ K +++ E SP K E K K
Sbjct: 511 SPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP--EKAKSPAKEEAKSPPEAKSPE 568
Query: 1260 KEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKP 1319
KEE K + S K P KEE KS P+ +K S KE+ K+ A P
Sbjct: 569 KEEAKSPAEVKS---PEKAKSPAKEEAKS----PAEAKSPEKAKSPVKEEAKSPAEAKSP 621
Query: 1320 IKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSI 1379
+K + K+ SP T + K P KS P + +
Sbjct: 622 VKEE--AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKS-------PEKAKSPVKA 672
Query: 1380 KSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQ 1439
++ PV E+ + + +A E+ K +E+ EK++ E
Sbjct: 673 EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA--KSPVKEEAKSPEKAKSPVKEEA 730
Query: 1440 ILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGP-NILNP 1498
P P P +P A+ + +P P + SP P +P
Sbjct: 731 KTPEKAKSPVKEEAKSP--EKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788
Query: 1499 VLPVAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNS 1558
V + + D AP E + + + S + P E KK E+ +
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAP-EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Query: 1559 CLATANAKDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKSSDTSSTSPL 1618
AT ++ D S + AP+ K AP+ K+ E + K ++ +
Sbjct: 848 -PATPKTEEKKD----SKKEEAPK-KEAPKPKVE-------EKKEPAVEKPKESKVEAKK 894
Query: 1619 NSSASQEELHQDEGLVAAPI-VSNSEKPIAKTLVA 1652
+ ++++ E A + V KP KT VA
Sbjct: 895 EEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA 929
Score = 45.1 bits (105), Expect = 8e-04
Identities = 91/403 (22%), Positives = 135/403 (33%), Gaps = 48/403 (11%)
Query: 1191 ETERRRQSELKRKLSEKPKEEKK--EKKAKAVKEVKEDDKVSE--KLEDQLSEGRNSPEK 1246
++ + +S +K + ++ P E K +++AK+ EVK +K K E + E SPEK
Sbjct: 599 KSPEKAKSPVKEE-AKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657
Query: 1247 AE----NKRNTGIKLQLKEEVKKESPT-SSSFGKFSWKKPEKEEEKSSLVTPSISKEEIL 1301
E K + +K + K K +SP + + K P KEE KS S KEE
Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717
Query: 1302 ESSKDKEDGKTEAGKAKPIK--IKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVL 1359
K K K EA + K +K K+ SP T P P+
Sbjct: 718 SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP----EKAKTLDVKSPEAKTPAKEE 773
Query: 1360 RKSCSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKG 1419
+S + + A +KS PL D P I K EEV
Sbjct: 774 ARSPADKFPEKAKSPVKEEVKSPEKAKSPL------KEDAKAPEKEIPKK---EEVKSPV 824
Query: 1420 SPEEKVVLAEKSEPSHLPEQILPPPPP-----------PPPPPPPPPPVIPHPAAPSAAQ 1468
EEK + EP E+ P P P P P + P+ +
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 1469 ANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSESD-- 1526
K + P P + A P ++T E D
Sbjct: 885 PKESKVEAKKEEAEDKKKVP--------TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDA 936
Query: 1527 --RDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKD 1567
++ + + P E+AKK E++ A A D
Sbjct: 937 KAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979
Score = 42.4 bits (98), Expect = 0.005
Identities = 40/212 (18%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Query: 848 QKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKNDREARQK 907
+KE ++ + + P +V + + P+K +EK A+ K + ++ +K + ++ K
Sbjct: 816 KKEEVKSPVKEEEKPQEVKV----KEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK 871
Query: 908 KMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAE 967
+ E ++ ++ KK +D K P + + + + +D A+ +++ E A+
Sbjct: 872 PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED-AKPKEKTEVAK 930
Query: 968 KKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNSSSNKESK 1027
K+ + + S+ + P +K K EK+K PE+ + +
Sbjct: 931 KEPDDAKAK---------EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Query: 1028 VNNEKFRTKSPKPAESPQSATKQLDQPTAAYE 1059
++ E + K+ K +S + K P A E
Sbjct: 982 LSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013
Score = 37.0 bits (84), Expect = 0.22
Identities = 63/268 (23%), Positives = 114/268 (42%), Gaps = 38/268 (14%)
Query: 1726 PPGVEPPPQL---LDIQCKESQKLVEIHLRESVNQDKESQELRKSEDCRESEIETNTELK 1782
P G+ P + + ++ +E K+VE +E+V +++++E + +E+ E E E K
Sbjct: 423 PEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEE---EKEAK 479
Query: 1783 ERVKELSEGIVDE----GVSTSIGPHSIDDSNLNHGNRYMWEGEVKQPNLLMIDKEAEQS 1838
E + EG +E G + P + + ++ + + E K P ++ E
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK 539
Query: 1839 N----KLMTGSETPSKVVIKLSPQACSFTKAKLDSFLSEARSLLNPQDTPVKISAPELLL 1894
+ K +++P+K K P+A S K EA+S P ++ +PE
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEK-------EEAKS-------PAEVKSPEKA- 584
Query: 1895 HSPARSAMCLTGSPQEQGVSVVSEEGLENSAPESASRTSRYRSLKLKRERSKDFQVKKIY 1954
SPA+ SP E S E ++ E A + +S +K E +VK
Sbjct: 585 KSPAKEE---AKSPAE----AKSPEKAKSPVKEEAKSPAEAKS-PVKEEAKSPAEVKSPE 636
Query: 1955 EL-AVWDENKKRPETWESPEKPKTEALE 1981
+ + E K PE +SPEK + ++ E
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEEAKSPE 664
Score = 33.1 bits (74), Expect = 3.2
Identities = 19/90 (21%), Positives = 39/90 (43%), Gaps = 3/90 (3%)
Query: 3 RSSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSG 62
+ A+S + P+ + P +S + PA+ + PP + S + A +SP+
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEA---KSPAE 577
Query: 63 HRGRRASPSPPRGRRVSPSPPRARRGSPSP 92
+ + SP + SP+ ++ + SP
Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 63.9 bits (154), Expect = 2e-09
Identities = 85/347 (24%), Positives = 144/347 (41%), Gaps = 44/347 (12%)
Query: 1205 SEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRN---SPEKAENKRNTGIKLQLKE 1261
+E ++EK+++K K + E +KV D+ E + PE AE+ N L +
Sbjct: 169 TEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANL-----LHK 223
Query: 1262 EVKKESPTSSSFGKFSWKKPEKEEEKSSL-VTPSISKEEILESSKDKEDGKTE------- 1313
++ + +S F + + SL P E+L ++++ +
Sbjct: 224 HIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPP 283
Query: 1314 ---AGKAKPIKIKLSGKTVVAHTSPWMPVVTTS----TQTKIRPNLPIPSTV----LRKS 1362
AG AKPI +S T + P P + + T P P+PS + LR S
Sbjct: 284 MHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRAS 343
Query: 1363 CSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFG--GEEVILKGS 1420
++T P P TA P V A L + P ++ A ++
Sbjct: 344 MTSTPPPPVP-----PPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSP 398
Query: 1421 PEEKVVLAEKSEPSH-LPE-QILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKS 1478
P + ++ P H LP+ ++ PPPPPPPP PPP + P++P A LA S
Sbjct: 399 PVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGI--RPSSPVTVTA---LAHPPS 453
Query: 1479 NPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSES 1525
+ + +PG P ++ P P ++ +++P PS T P +S++
Sbjct: 454 GLHPTPSTAPGPHVP-LMPPSPPSQVIPASEPKRHPS--TLPVISDA 497
Score = 48.5 bits (114), Expect = 7e-05
Identities = 50/159 (31%), Positives = 64/159 (40%), Gaps = 18/159 (11%)
Query: 1386 AKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKV--VLAEKSEPSHLPEQILPP 1443
AKP+P SSA L+ S A G V + +P + + S S P
Sbjct: 290 AKPIPTCI-SSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTP 348
Query: 1444 PPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVA 1503
PPP PPPPPPP + PA P AP++ P V P + P ++ P PVA
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPP------APLQIAPGVLHPAPPP-IAPPLVQPSPPVA 401
Query: 1504 IMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPL 1542
A P ET P V + + PPPPL
Sbjct: 402 -------RAAPVCETVP-VHPLPQGEVQGLPPPPPPPPL 432
Score = 33.1 bits (74), Expect = 3.2
Identities = 30/99 (30%), Positives = 38/99 (38%), Gaps = 21/99 (21%)
Query: 25 SGRSSGSSSGPARRSSPPPPPSGSSSRTPA-RRPRSPSGHRGRRASPSPP--RGRRVSPS 81
S + +S P PPPPP ++ + PA P +P P+PP V PS
Sbjct: 338 SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Query: 82 PPRAR------------------RGSPSPPRGRRLFPPG 102
PP AR +G P PP L PPG
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPG 436
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 63.9 bits (154), Expect = 2e-09
Identities = 85/347 (24%), Positives = 144/347 (41%), Gaps = 44/347 (12%)
Query: 1205 SEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRN---SPEKAENKRNTGIKLQLKE 1261
+E ++EK+++K K + E +KV D+ E + PE AE+ N L +
Sbjct: 169 TEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANL-----LHK 223
Query: 1262 EVKKESPTSSSFGKFSWKKPEKEEEKSSL-VTPSISKEEILESSKDKEDGKTE------- 1313
++ + +S F + + SL P E+L ++++ +
Sbjct: 224 HIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPP 283
Query: 1314 ---AGKAKPIKIKLSGKTVVAHTSPWMPVVTTS----TQTKIRPNLPIPSTV----LRKS 1362
AG AKPI +S T + P P + + T P P+PS + LR S
Sbjct: 284 MHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRAS 343
Query: 1363 CSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFG--GEEVILKGS 1420
++T P P TA P V A L + P ++ A ++
Sbjct: 344 MTSTPPPPVP-----PPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSP 398
Query: 1421 PEEKVVLAEKSEPSH-LPE-QILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKS 1478
P + ++ P H LP+ ++ PPPPPPPP PPP + P++P A LA S
Sbjct: 399 PVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGI--RPSSPVTVTA---LAHPPS 453
Query: 1479 NPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSES 1525
+ + +PG P ++ P P ++ +++P PS T P +S++
Sbjct: 454 GLHPTPSTAPGPHVP-LMPPSPPSQVIPASEPKRHPS--TLPVISDA 497
Score = 48.5 bits (114), Expect = 7e-05
Identities = 50/159 (31%), Positives = 64/159 (40%), Gaps = 18/159 (11%)
Query: 1386 AKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKV--VLAEKSEPSHLPEQILPP 1443
AKP+P SSA L+ S A G V + +P + + S S P
Sbjct: 290 AKPIPTCI-SSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTP 348
Query: 1444 PPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVA 1503
PPP PPPPPPP + PA P AP++ P V P + P ++ P PVA
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPP------APLQIAPGVLHPAPPP-IAPPLVQPSPPVA 401
Query: 1504 IMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPL 1542
A P ET P V + + PPPPL
Sbjct: 402 -------RAAPVCETVP-VHPLPQGEVQGLPPPPPPPPL 432
Score = 33.1 bits (74), Expect = 3.2
Identities = 30/99 (30%), Positives = 38/99 (38%), Gaps = 21/99 (21%)
Query: 25 SGRSSGSSSGPARRSSPPPPPSGSSSRTPA-RRPRSPSGHRGRRASPSPP--RGRRVSPS 81
S + +S P PPPPP ++ + PA P +P P+PP V PS
Sbjct: 338 SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Query: 82 PPRAR------------------RGSPSPPRGRRLFPPG 102
PP AR +G P PP L PPG
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPG 436
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 63.9 bits (154), Expect = 2e-09
Identities = 85/347 (24%), Positives = 144/347 (41%), Gaps = 44/347 (12%)
Query: 1205 SEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRN---SPEKAENKRNTGIKLQLKE 1261
+E ++EK+++K K + E +KV D+ E + PE AE+ N L +
Sbjct: 169 TEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANL-----LHK 223
Query: 1262 EVKKESPTSSSFGKFSWKKPEKEEEKSSL-VTPSISKEEILESSKDKEDGKTE------- 1313
++ + +S F + + SL P E+L ++++ +
Sbjct: 224 HIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPP 283
Query: 1314 ---AGKAKPIKIKLSGKTVVAHTSPWMPVVTTS----TQTKIRPNLPIPSTV----LRKS 1362
AG AKPI +S T + P P + + T P P+PS + LR S
Sbjct: 284 MHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRAS 343
Query: 1363 CSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFG--GEEVILKGS 1420
++T P P TA P V A L + P ++ A ++
Sbjct: 344 MTSTPPPPVP-----PPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSP 398
Query: 1421 PEEKVVLAEKSEPSH-LPE-QILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKS 1478
P + ++ P H LP+ ++ PPPPPPPP PPP + P++P A LA S
Sbjct: 399 PVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGI--RPSSPVTVTA---LAHPPS 453
Query: 1479 NPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSES 1525
+ + +PG P ++ P P ++ +++P PS T P +S++
Sbjct: 454 GLHPTPSTAPGPHVP-LMPPSPPSQVIPASEPKRHPS--TLPVISDA 497
Score = 48.5 bits (114), Expect = 7e-05
Identities = 50/159 (31%), Positives = 64/159 (40%), Gaps = 18/159 (11%)
Query: 1386 AKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKV--VLAEKSEPSHLPEQILPP 1443
AKP+P SSA L+ S A G V + +P + + S S P
Sbjct: 290 AKPIPTCI-SSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTP 348
Query: 1444 PPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVA 1503
PPP PPPPPPP + PA P AP++ P V P + P ++ P PVA
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPP------APLQIAPGVLHPAPPP-IAPPLVQPSPPVA 401
Query: 1504 IMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPL 1542
A P ET P V + + PPPPL
Sbjct: 402 -------RAAPVCETVP-VHPLPQGEVQGLPPPPPPPPL 432
Score = 33.1 bits (74), Expect = 3.2
Identities = 30/99 (30%), Positives = 38/99 (38%), Gaps = 21/99 (21%)
Query: 25 SGRSSGSSSGPARRSSPPPPPSGSSSRTPA-RRPRSPSGHRGRRASPSPP--RGRRVSPS 81
S + +S P PPPPP ++ + PA P +P P+PP V PS
Sbjct: 338 SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Query: 82 PPRAR------------------RGSPSPPRGRRLFPPG 102
PP AR +G P PP L PPG
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPG 436
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 63.9 bits (154), Expect = 2e-09
Identities = 85/347 (24%), Positives = 144/347 (41%), Gaps = 44/347 (12%)
Query: 1205 SEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRN---SPEKAENKRNTGIKLQLKE 1261
+E ++EK+++K K + E +KV D+ E + PE AE+ N L +
Sbjct: 169 TEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANL-----LHK 223
Query: 1262 EVKKESPTSSSFGKFSWKKPEKEEEKSSL-VTPSISKEEILESSKDKEDGKTE------- 1313
++ + +S F + + SL P E+L ++++ +
Sbjct: 224 HIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPP 283
Query: 1314 ---AGKAKPIKIKLSGKTVVAHTSPWMPVVTTS----TQTKIRPNLPIPSTV----LRKS 1362
AG AKPI +S T + P P + + T P P+PS + LR S
Sbjct: 284 MHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRAS 343
Query: 1363 CSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFG--GEEVILKGS 1420
++T P P TA P V A L + P ++ A ++
Sbjct: 344 MTSTPPPPVP-----PPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSP 398
Query: 1421 PEEKVVLAEKSEPSH-LPE-QILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKS 1478
P + ++ P H LP+ ++ PPPPPPPP PPP + P++P A LA S
Sbjct: 399 PVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGI--RPSSPVTVTA---LAHPPS 453
Query: 1479 NPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSES 1525
+ + +PG P ++ P P ++ +++P PS T P +S++
Sbjct: 454 GLHPTPSTAPGPHVP-LMPPSPPSQVIPASEPKRHPS--TLPVISDA 497
Score = 48.5 bits (114), Expect = 7e-05
Identities = 50/159 (31%), Positives = 64/159 (40%), Gaps = 18/159 (11%)
Query: 1386 AKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKV--VLAEKSEPSHLPEQILPP 1443
AKP+P SSA L+ S A G V + +P + + S S P
Sbjct: 290 AKPIPTCI-SSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTP 348
Query: 1444 PPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVA 1503
PPP PPPPPPP + PA P AP++ P V P + P ++ P PVA
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPP------APLQIAPGVLHPAPPP-IAPPLVQPSPPVA 401
Query: 1504 IMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPL 1542
A P ET P V + + PPPPL
Sbjct: 402 -------RAAPVCETVP-VHPLPQGEVQGLPPPPPPPPL 432
Score = 33.1 bits (74), Expect = 3.2
Identities = 30/99 (30%), Positives = 38/99 (38%), Gaps = 21/99 (21%)
Query: 25 SGRSSGSSSGPARRSSPPPPPSGSSSRTPA-RRPRSPSGHRGRRASPSPP--RGRRVSPS 81
S + +S P PPPPP ++ + PA P +P P+PP V PS
Sbjct: 338 SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Query: 82 PPRAR------------------RGSPSPPRGRRLFPPG 102
PP AR +G P PP L PPG
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPG 436
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 63.5 bits (153), Expect = 2e-09
Identities = 106/480 (22%), Positives = 185/480 (38%), Gaps = 60/480 (12%)
Query: 1161 NEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKAV 1220
NE YK V + RR +Q + ++++Q + R E+ E++KEK+A+
Sbjct: 476 NENYKSLVRRS---YRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKE 532
Query: 1221 KEVKE-----DDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEVKKESPTSSSFGK 1275
+E E +D + EK +D E + E +K Q + + + ++
Sbjct: 533 EEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANS 592
Query: 1276 FSWKKPEKEEEKSSLVTPSISK--EEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHT 1333
P++ E +S+ S+ EE +E++K G E G+ ++ G V+
Sbjct: 593 EEAITPQQSAELASMELNESSRWTEEEMETAKK---GLLEHGRNWSAIARMVGSKTVSQC 649
Query: 1334 SPW-------MPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPA---PLNTFLSIKSSG 1383
+ + Q K++ + +K A S+ A P+ +++SG
Sbjct: 650 KNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASG 709
Query: 1384 TTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPP 1443
+ +V+E+ A ++ G + S E + + +E + Q P
Sbjct: 710 VSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIP-SPHTEAAKDTGQNGPK 768
Query: 1444 PP-------PPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNIL 1496
PP PPP PP PPP IP P P+ A S + T P P+
Sbjct: 769 PPATLGADGPPPGPPTPPPEDIPAPTEPTPA----------SEATGAPTPPPAPPSPSAP 818
Query: 1497 NPVLPVAIMASAQPAAIP---SDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKK- 1552
PV+P AA P +E P +E T + P+ S +E+A++
Sbjct: 819 PPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDT-----GKAEEPVKSECTEEAEEG 873
Query: 1553 -LEKRNSCLATANAKDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKSSD 1611
+ +++ A A A+ GG G T K SG P ++S+ S T S+D
Sbjct: 874 PAKGKDAEAAEATAEGALKAEKKEGGSGRATT-----AKSSGAP----QDSDSSATCSAD 924
Score = 34.7 bits (78), Expect = 1.1
Identities = 123/615 (20%), Positives = 198/615 (32%), Gaps = 127/615 (20%)
Query: 1208 PKEEKKEKKAKAVKEVKED---------DKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQ 1258
P EE +E+K A +E+ D + +E+ E+ ++G+++ E AE +K +
Sbjct: 836 PVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDA-EAAEATAEGALKAE 894
Query: 1259 LKEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSK----------DKE 1308
KE + T+ S G P+ + ++ + + E + ++
Sbjct: 895 KKEGGSGRATTAKSSGA-----PQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTG 949
Query: 1309 DGKTEAGKAKPIKIKLSGKTVVAH----TSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCS 1364
D + A KP+ +K + A T P + TK P P P L+
Sbjct: 950 DPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESD 1009
Query: 1365 ATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPE-- 1422
A P S + + P P KE+ + P AF E L G P
Sbjct: 1010 A------PQQPGSSPRGKSRSPAP-PADKEAEKPVFFP------AFAAEAQKLPGDPPCW 1056
Query: 1423 ----------EKVVLAEKSEPSHLPEQILPPPPP--------------PPPPPPPPPPVI 1458
+V+ A P PP P PP PPP+I
Sbjct: 1057 TSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLI 1116
Query: 1459 PHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDET 1518
PS + + +SQ +S P + PV + P + +
Sbjct: 1117 SSAKHPSVLE--------RQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKL 1168
Query: 1519 APGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGK 1578
AP S ++Q PP L +++A L R + L +
Sbjct: 1169 AP-FSGVKQEQLSPRGQAGPPESLGVPTAQEASVL--RGTALGSV--------------P 1211
Query: 1579 GAPETKGAPETKLSGGPLANGENSNLSRTKS----SDTSSTSPLNSSASQEELHQDEGLV 1634
G TKG P T++ S T + T + S S+ + +++ L
Sbjct: 1212 GGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSLP 1271
Query: 1635 AAPIVSNSEKPIAKTLVALGKWSVVEHVGPKSTGSTYGFLQPLTRLCQSRPYETITPKTD 1694
++ +K L G SV + K G R P+ET PK
Sbjct: 1272 KGHVIYEGKK--GHVLSYEGGMSVTQ--CSKEDG----------RSSSGPPHETAAPKR- 1316
Query: 1695 TLAIWTSSSFQSDTSRDISPEKSELDLGEPGPPGVEPPPQLLDIQCKESQKLVEIHLRES 1754
T + R IS E +G PP P L + + H+R S
Sbjct: 1317 -----TYDMMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKE----------QHHIRGS 1361
Query: 1755 VNQDKESQELRKSED 1769
+ Q + ED
Sbjct: 1362 ITQGIPRSYVEAQED 1376
Score = 33.1 bits (74), Expect = 3.2
Identities = 21/92 (22%), Positives = 31/92 (33%), Gaps = 9/92 (9%)
Query: 16 KDDGGGGPRSGRSSGSSSGPARRSSPP---------PPPSGSSSRTPARRPRSPSGHRGR 66
KD G GP+ + G+ P +PP P P+ ++ P P PS
Sbjct: 760 KDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPP 819
Query: 67 RASPSPPRGRRVSPSPPRARRGSPSPPRGRRL 98
P + + +PP PP L
Sbjct: 820 PVVPKEEKEEETAAAPPVEEGEEQKPPAAEEL 851
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 63.5 bits (153), Expect = 2e-09
Identities = 98/362 (27%), Positives = 140/362 (38%), Gaps = 68/362 (18%)
Query: 4 SSARSSVSSHRPK-DDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSG 62
++A S V++ +P GGP GR++ ARR S S S+SRT + R S S
Sbjct: 345 AAAASGVTTGKPPAPPQPGGPAPGRNAS-----ARRRSSSSSSSSSASRTSSSRSSSRSS 399
Query: 63 HRGRRASP-------SPPRGRRVSPSPPRARRGSPSPPRGRR-------------LFPPG 102
R RR + R R S S R+RR S S RGRR P
Sbjct: 400 SRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR 459
Query: 103 PAGF----RGSSRGESRADYARDGRGDHPGDSGSRRRSPGLCSDSLEKSLRITVGNDHFC 158
G+ R SR S Y R GRG S SR RS S S +SL T H
Sbjct: 460 RGGYGPRRRSRSRSHSGDRYRRGGRGLR-HHSSSRSRSSWSLSPSRSRSL--TRSRSHSP 516
Query: 159 VSTPERRRLSDRLGSPVDNLEDMDRDDLTDDSVFTRSSQCSRGLERYISQEEGPLSPFLG 218
+ R R R SP + R+ LT + + + E +E G P L
Sbjct: 517 SPSQSRSRSRSRSQSPSPS---PAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLT 573
Query: 219 QLDEDYRTKETFLHRSDYSPHISCHDELLRGTERNRE-----KLKGYSIRSEERS-REAK 272
++ + L+R + + +++++ +E + IR +ER RE +
Sbjct: 574 PQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKE 633
Query: 273 RPRYDDTVKINSMGGDHPSFTSGTRNYRQRRRSPSPRFLDPEFRELDLARRKREEEEERS 332
R ++ R Y ++ RSPSPR+ RE +RR+ RS
Sbjct: 634 REEWE-------------------RQYSRQSRSPSPRY----SREYSSSRRR---SRSRS 667
Query: 333 RS 334
RS
Sbjct: 668 RS 669
Score = 40.8 bits (94), Expect = 0.015
Identities = 44/120 (36%), Positives = 48/120 (40%), Gaps = 18/120 (15%)
Query: 3 RSSARSSVSSHR----PKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPR 58
R S S HR P GG GPR S S SG R SSSR+ +
Sbjct: 441 RHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSL 500
Query: 59 SPSGH----RGRRASPSP------PRGRRVSPSPPRAR----RGSPSPPRGRRLFPPGPA 104
SPS R R SPSP R R SPSP AR R + SP G +L PA
Sbjct: 501 SPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPA 560
Score = 32.0 bits (71), Expect = 7.1
Identities = 35/149 (23%), Positives = 57/149 (38%), Gaps = 9/149 (6%)
Query: 793 HYMAYAASRWPMYP------TSQPSNHPVPEPHRIMPITKQATRSRPNLRVIPTVTPDKP 846
H + + S W + P T S+ P P R ++ + S R T P
Sbjct: 489 HSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASP 548
Query: 847 KQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEK--NRASQKQKVIEEREKLKNDREA 904
E L+ + PAA + P L K+ +K NR + K + EK+
Sbjct: 549 AVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQ-EKMIQQEHE 607
Query: 905 RQKKMYYLRTELERLHKQQGEMLRKKRRE 933
RQ++ LR ++ ++ E K+R E
Sbjct: 608 RQEREDELRAMARKIRMKERERREKEREE 636
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 62.0 bits (149), Expect = 6e-09
Identities = 79/345 (22%), Positives = 130/345 (37%), Gaps = 52/345 (15%)
Query: 1203 KLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSP----EKAENKRNTGIKLQ 1258
K S KP +KK KK +E+ E+ VSE E S +S K ++ +N+ +
Sbjct: 93 KRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRE 152
Query: 1259 LKEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAK 1318
L++++K + + K KP +E S + K ++S + +
Sbjct: 153 LQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHN--------- 203
Query: 1319 PIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLS 1378
K+ S P +TT+ RP+LP P++ K S T++K + T +
Sbjct: 204 --KVSTS------------PKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKET 248
Query: 1379 I----------KSSGTTAKPLPVVKESSADLLLPPD-IISKAFGGEEVILKG----SPEE 1423
K T+AK ++++SA L P +++K E KG +P+E
Sbjct: 249 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 308
Query: 1424 KVVLAEKSEPSHLPEQILP--------PPPPPPPPPPPPPPVIPHPAAPSAAQANAILAP 1475
K S P++ P P P P P P AP+ + A P
Sbjct: 309 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 368
Query: 1476 VKSNPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAP 1520
+ P ++ +P P P A +PA E AP
Sbjct: 369 KEPAPTTTKEPAPTTTKSAPTTPKEP-APTTPKKPAPTTPKEPAP 412
Score = 62.0 bits (149), Expect = 6e-09
Identities = 179/850 (21%), Positives = 278/850 (32%), Gaps = 101/850 (11%)
Query: 987 KSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNSS------SNKESKVNNEKFRTKSPKP 1040
K K + +S E TE+ +E +S SS S+SS S+K S N E + K
Sbjct: 102 KKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKD 161
Query: 1041 AESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQ----TLDP 1096
+ ++ K +P E AG+ D T D T HNK T T P
Sbjct: 162 NKKNRTKKKPTPKPPVVDE---AGSGL--DNGDFKVTTPDTSTTQHNKVSTSPKITTAKP 216
Query: 1097 YN-RPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQLCEEFLGDPISGEQHV 1155
N RP +K+ ++ + TV K + ++ D
Sbjct: 217 INPRPSLPPNSDTSKETSLTVNKETTVETKETT----------TTNKQTSTDGKEKTTSA 266
Query: 1156 KGHQHNEKY--KKYVDENPLYEERRNLDRQAGLAVVLETERR-RQSELKRKLSEKPKEEK 1212
K Q EK K + + + L T + + K S PKE
Sbjct: 267 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 326
Query: 1213 KEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEVKKESPTSSS 1272
A KE + K + +P + T K K+ +PT++
Sbjct: 327 PTTIKSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385
Query: 1273 FGKFSWKKPEKEEEKSSLVT------PSISKEEILESSKD-----KEDGKTEAGKAKPIK 1321
+ K+P K T P+ KE + K+ KE T + P
Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 445
Query: 1322 IKLSGKTVVAHTSPWMPVVTTSTQTK----IRPNLPIPSTVLRKSCSATMSKPAPLNTFL 1377
K T +P P T TK P P P+T KS T +PAP T
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT--KSAPTTTKEPAPTTT-- 501
Query: 1378 SIKSSGTTAK-PLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHL 1436
KS+ TT K P P + A +P+E K
Sbjct: 502 --KSAPTTPKEPSPTTTKEPAPT--------------------TPKEPAPTTPKKPAPTT 539
Query: 1437 PEQILPPPPPPPPPPPP--PPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPN 1494
P++ P P P P P P P AP+ + A P K P + L+P P
Sbjct: 540 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP--TTPE 597
Query: 1495 ILNPVLP--VAIMASAQPAAIPSDETAPGVSESDRDQT-LFSVLVRPPPPLSSVFSEQAK 1551
P P +A +P +E AP ++ T P P + E A
Sbjct: 598 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657
Query: 1552 KLEKRNSCLATANA--KDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKS 1609
K + L + ++ K AP+ + AP T + + + +
Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDKPAPTTPKGT 716
Query: 1610 SDTSSTSPLNSSASQEELHQDEG----LVAAPIVSNSEKPIAKTL---VALGKWSVVEH- 1661
+ T+ P ++ + +G + P + +KP K L G S
Sbjct: 717 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 776
Query: 1662 ---VGPKSTGSTYGFLQPLTRLCQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSE 1718
PK T T T + P TP T + T ++ + T+ SP++S
Sbjct: 777 PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 836
Query: 1719 LDL-GEPGPPGVEPPPQLLDIQCKESQKLVEIHLRESVNQDKESQELRKSEDCRESEIET 1777
+L EP P +E P+ + ++ + + + ++LR + ET
Sbjct: 837 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-------ET 889
Query: 1778 NTELKERVKE 1787
T + KE
Sbjct: 890 TTAAPKMTKE 899
Score = 33.5 bits (75), Expect = 2.5
Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 16/110 (14%)
Query: 806 PTSQPSNHPVPEPHRIMPITKQATRSRPNLRVIPTVTPDKPKQKESLRG-------SIPA 858
PTS PS+ P P K T+ P P+K K K+ + S+
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKRSPK-------PPNKKKTKKVIESEEITEEHSVSE 121
Query: 859 AQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKNDREARQKK 908
Q S S KI KN A+ ++ ++++ K+K++++ R KK
Sbjct: 122 NQESSSSSSSSSSSSTIRKIKSSKNSAANRE--LQKKLKVKDNKKNRTKK 169
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 62.0 bits (149), Expect = 6e-09
Identities = 79/345 (22%), Positives = 130/345 (37%), Gaps = 52/345 (15%)
Query: 1203 KLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSP----EKAENKRNTGIKLQ 1258
K S KP +KK KK +E+ E+ VSE E S +S K ++ +N+ +
Sbjct: 134 KRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRE 193
Query: 1259 LKEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAK 1318
L++++K + + K KP +E S + K ++S + +
Sbjct: 194 LQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHN--------- 244
Query: 1319 PIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLS 1378
K+ S P +TT+ RP+LP P++ K S T++K + T +
Sbjct: 245 --KVSTS------------PKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKET 289
Query: 1379 I----------KSSGTTAKPLPVVKESSADLLLPPD-IISKAFGGEEVILKG----SPEE 1423
K T+AK ++++SA L P +++K E KG +P+E
Sbjct: 290 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 349
Query: 1424 KVVLAEKSEPSHLPEQILP--------PPPPPPPPPPPPPPVIPHPAAPSAAQANAILAP 1475
K S P++ P P P P P P AP+ + A P
Sbjct: 350 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 409
Query: 1476 VKSNPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAP 1520
+ P ++ +P P P A +PA E AP
Sbjct: 410 KEPAPTTTKEPAPTTTKSAPTTPKEP-APTTPKKPAPTTPKEPAP 453
Score = 62.0 bits (149), Expect = 6e-09
Identities = 179/850 (21%), Positives = 278/850 (32%), Gaps = 101/850 (11%)
Query: 987 KSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNSS------SNKESKVNNEKFRTKSPKP 1040
K K + +S E TE+ +E +S SS S+SS S+K S N E + K
Sbjct: 143 KKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKD 202
Query: 1041 AESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQ----TLDP 1096
+ ++ K +P E AG+ D T D T HNK T T P
Sbjct: 203 NKKNRTKKKPTPKPPVVDE---AGSGL--DNGDFKVTTPDTSTTQHNKVSTSPKITTAKP 257
Query: 1097 YN-RPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQLCEEFLGDPISGEQHV 1155
N RP +K+ ++ + TV K + ++ D
Sbjct: 258 INPRPSLPPNSDTSKETSLTVNKETTVETKETT----------TTNKQTSTDGKEKTTSA 307
Query: 1156 KGHQHNEKY--KKYVDENPLYEERRNLDRQAGLAVVLETERR-RQSELKRKLSEKPKEEK 1212
K Q EK K + + + L T + + K S PKE
Sbjct: 308 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 367
Query: 1213 KEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEVKKESPTSSS 1272
A KE + K + +P + T K K+ +PT++
Sbjct: 368 PTTIKSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426
Query: 1273 FGKFSWKKPEKEEEKSSLVT------PSISKEEILESSKD-----KEDGKTEAGKAKPIK 1321
+ K+P K T P+ KE + K+ KE T + P
Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 486
Query: 1322 IKLSGKTVVAHTSPWMPVVTTSTQTK----IRPNLPIPSTVLRKSCSATMSKPAPLNTFL 1377
K T +P P T TK P P P+T KS T +PAP T
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT--KSAPTTTKEPAPTTT-- 542
Query: 1378 SIKSSGTTAK-PLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHL 1436
KS+ TT K P P + A +P+E K
Sbjct: 543 --KSAPTTPKEPSPTTTKEPAPT--------------------TPKEPAPTTPKKPAPTT 580
Query: 1437 PEQILPPPPPPPPPPPP--PPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPN 1494
P++ P P P P P P P AP+ + A P K P + L+P P
Sbjct: 581 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP--TTPE 638
Query: 1495 ILNPVLP--VAIMASAQPAAIPSDETAPGVSESDRDQT-LFSVLVRPPPPLSSVFSEQAK 1551
P P +A +P +E AP ++ T P P + E A
Sbjct: 639 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698
Query: 1552 KLEKRNSCLATANA--KDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKS 1609
K + L + ++ K AP+ + AP T + + + +
Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDKPAPTTPKGT 757
Query: 1610 SDTSSTSPLNSSASQEELHQDEG----LVAAPIVSNSEKPIAKTL---VALGKWSVVEH- 1661
+ T+ P ++ + +G + P + +KP K L G S
Sbjct: 758 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 817
Query: 1662 ---VGPKSTGSTYGFLQPLTRLCQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSE 1718
PK T T T + P TP T + T ++ + T+ SP++S
Sbjct: 818 PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 877
Query: 1719 LDL-GEPGPPGVEPPPQLLDIQCKESQKLVEIHLRESVNQDKESQELRKSEDCRESEIET 1777
+L EP P +E P+ + ++ + + + ++LR + ET
Sbjct: 878 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-------ET 930
Query: 1778 NTELKERVKE 1787
T + KE
Sbjct: 931 TTAAPKMTKE 940
Score = 33.5 bits (75), Expect = 2.5
Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 16/110 (14%)
Query: 806 PTSQPSNHPVPEPHRIMPITKQATRSRPNLRVIPTVTPDKPKQKESLRG-------SIPA 858
PTS PS+ P P K T+ P P+K K K+ + S+
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPK-------PPNKKKTKKVIESEEITEEHSVSE 162
Query: 859 AQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKNDREARQKK 908
Q S S KI KN A+ ++ ++++ K+K++++ R KK
Sbjct: 163 NQESSSSSSSSSSSSTIRKIKSSKNSAANRE--LQKKLKVKDNKKNRTKK 210
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 62.0 bits (149), Expect = 6e-09
Identities = 52/168 (30%), Positives = 71/168 (42%), Gaps = 37/168 (22%)
Query: 1420 SPEEKVVLA-EKSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPSAAQA--------- 1469
SP+ K+V S+PS PPPPPPPPPPPPPPP +P +APSA A
Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669
Query: 1470 -----------NAILAPVKSNPVVSQTLSPG-FVGPNIL--------NPVLPVAIMASAQ 1509
A+ P + SQ++ P V PN + P P + MA +
Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLK 729
Query: 1510 PA----AIPSDETAPGVSESDRDQTLFSV---LVRPPPPLSSVFSEQA 1550
PA ++P P + + Q + V PPPP+ + QA
Sbjct: 730 PAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA 777
Score = 55.5 bits (132), Expect = 6e-07
Identities = 75/283 (26%), Positives = 101/283 (35%), Gaps = 63/283 (22%)
Query: 1313 EAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAP 1372
E+ KA+ + ++V SP +VT T ++ P LP P P P
Sbjct: 589 ESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPP 648
Query: 1373 LNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSE 1432
L + S S+G+ A VK S+ L S A L P V+ ++ +
Sbjct: 649 LPS-QSAPSAGSAAPMF--VKYSTITRLQNASQHSGA-------LFKPPTPPVMQSQSVK 698
Query: 1433 PSHL--PEQILPPPPPPPPPP--------------------------------------- 1451
P L P ++PPPPPPPPPP
Sbjct: 699 PQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQV 758
Query: 1452 ----PPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGF--VGPNILNPVLPVAIM 1505
PPPPP IP P P A + P P ++T++P P P +P A
Sbjct: 759 APPTPPPPPPIPAPLPPQAPPKPLVTIPA---PTSTKTVAPVVTQAAPPTPTPPVPPAKK 815
Query: 1506 ASAQPAAI--PSDETAPGVSESDRDQTLFSVLVRPPP-PLSSV 1545
A PA+ PS T P S +PPP PLS V
Sbjct: 816 QPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPV 858
Score = 48.1 bits (113), Expect = 1e-04
Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 11/144 (7%)
Query: 1350 PNLPIPSTVLRKSCS-ATMSKPAPLNTFLSIK---SSGTTAKPLPVVKESSADLLLPPDI 1405
P +P+P L K S P+PL+ S+ +S P P ES +P ++
Sbjct: 831 PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANV 890
Query: 1406 ISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPS 1465
++ + K P + + P PE L PPPPP P P PPP P A+P+
Sbjct: 891 APQSPPAVKAKPKWQPSS-IPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPT 949
Query: 1466 AAQANAILAPVKSNPVVSQTLSPG 1489
++ +P K S+T SPG
Sbjct: 950 PDKSG---SPGKK---TSKTSSPG 967
Score = 47.8 bits (112), Expect = 1e-04
Identities = 61/218 (27%), Positives = 83/218 (38%), Gaps = 56/218 (25%)
Query: 1346 TKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDI 1405
T++ P P P + A + AP ++I + +T PVV +++ PP
Sbjct: 756 TQVAPPTPPPPPPI----PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP-- 809
Query: 1406 ISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPS 1465
V K +P+ I PP PP PP P PPP +P +
Sbjct: 810 --------------------VPPAKKQPAFPASYI--PPSPPTPPVPVPPPTLPKQQSFC 847
Query: 1466 AAQANAILAPVKSNPVVSQTLS-------PGFVGPNILNPV-------LPVAIMASA--Q 1509
A + L+PV S VV Q S P + L PV P A+ A Q
Sbjct: 848 AKPPPSPLSPVPS--VVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ 905
Query: 1510 PAAI--PSDETAPGVSESDRDQTLFSVLVRPPPPLSSV 1545
P++I PS + P ES LV PPPP S V
Sbjct: 906 PSSIPVPSPDFPPPPPESS--------LVFPPPPPSPV 935
Score = 37.4 bits (85), Expect = 0.17
Identities = 45/193 (23%), Positives = 75/193 (38%), Gaps = 32/193 (16%)
Query: 670 SSDPHRLESREAHHSNTHSPEVSHPHP--PSPVDPY-----LLTKNSPPFLKSDHPVGHI 722
S+ P L+ + H +P P P P+P+ P L+T +P K+ PV
Sbjct: 741 SAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQ 800
Query: 723 SG-----PEVVGSGFQSSVAVRCMLPSAPSAPIRLPHTAALSQFHMPRASQFAAARIPPN 777
+ P V + Q + + PS P+ P+ +P +P+ F A
Sbjct: 801 AAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPT------LPKQQSFCAKP---- 850
Query: 778 YQGPAIPPASFDAYRHYMAYAASRWPMYPT--SQPSNHPVPEPHRIMPITKQATRSRPNL 835
PP+ + AS++P PT + S P P + P + A +++P
Sbjct: 851 ------PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKW 904
Query: 836 R--VIPTVTPDKP 846
+ IP +PD P
Sbjct: 905 QPSSIPVPSPDFP 917
Score = 34.3 bits (77), Expect = 1.4
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 6/51 (11%)
Query: 35 PARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRAS-PSPPRGRRVSPSPPR 84
P+ +PPPPP ++S TP + SG G++ S S P G++ P+P R
Sbjct: 932 PSPVPAPPPPPPPTASPTPDK-----SGSPGKKTSKTSSPGGKKPPPTPQR 977
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 62.0 bits (149), Expect = 6e-09
Identities = 47/123 (38%), Positives = 59/123 (47%), Gaps = 11/123 (8%)
Query: 24 RSGRSSGSSSGPARRSSPPPPPSGSSS------RTPARRPRSPSGHRGRRASPSPPRGRR 77
R RS + P RR +P PPP + R+P+ R SP RR SPSPP RR
Sbjct: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQ--RRYSPSPPPKRR 613
Query: 78 -VSPSPPRARRGSPSPPRGRRLFPPGPAGFRGS--SRGESRADYARDGRGDHPGDSGSRR 134
SP PP RR SPSPP RR+ P R S ++ S + ++ +G P S
Sbjct: 614 TASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREA 673
Query: 135 RSP 137
RSP
Sbjct: 674 RSP 676
Score = 55.1 bits (131), Expect = 8e-07
Identities = 40/101 (39%), Positives = 47/101 (46%), Gaps = 10/101 (9%)
Query: 37 RRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGR 96
RR SPP S S P RR SP RRASPSPP RRVS SPP +R SP R
Sbjct: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKR-- 651
Query: 97 RLFPPGPAGFRGSSRGESRADYARDGRGDHPGDSGSRRRSP 137
P+ +G S + R+ R P ++R SP
Sbjct: 652 ----RSPSLSSKHRKGSSPSRSTREARSPQP----NKRHSP 684
Score = 54.7 bits (130), Expect = 1e-06
Identities = 47/137 (34%), Positives = 57/137 (41%), Gaps = 8/137 (5%)
Query: 4 SSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSG- 62
S + SS RPK GR S P+R +SP P + RR RSPS
Sbjct: 496 SGSSSSSEDERPKRSHVKNGEVGRRRRHS--PSRSASPSPRKRQKETSPRGRRRRSPSPP 553
Query: 63 --HRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRLFPPGPAGFRGSSRGESRADYAR 120
R R SP+PP RR +P+PP RR +PSPP RR P P + +
Sbjct: 554 PTRRRRSPSPAPPPRRRRTPTPPPRRR-TPSPPPRRR--SPSPRRYSPPIQRRYSPSPPP 610
Query: 121 DGRGDHPGDSGSRRRSP 137
R P RR SP
Sbjct: 611 KRRTASPPPPPKRRASP 627
Score = 51.6 bits (122), Expect = 9e-06
Identities = 39/103 (37%), Positives = 46/103 (44%), Gaps = 8/103 (7%)
Query: 3 RSSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSG 62
R + +SS S P+ G RR SP S S+S +P +R + S
Sbjct: 487 RQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSP----SRSASPSPRKRQKETSP 542
Query: 63 HRGRRASPSPP-RGRRVSPSP---PRARRGSPSPPRGRRLFPP 101
RR SPSPP RR SPSP PR RR PPR R PP
Sbjct: 543 RGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP 585
Score = 49.7 bits (117), Expect = 3e-05
Identities = 47/128 (36%), Positives = 53/128 (41%), Gaps = 45/128 (35%)
Query: 3 RSSARSSVSSH-RPKDDGGGGPRSGRSSGSSSGPARRSSP---------------PPPP- 45
RS RS SH RP+ R RS S P RR SP PPPP
Sbjct: 285 RSRTRSRSPSHTRPR-------RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR 337
Query: 46 ------------------SGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSP--SPPRA 85
SGSSS + + R RSP +R S P + RR+SP SPPR
Sbjct: 338 HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPR- 396
Query: 86 RRGSPSPP 93
RR PSPP
Sbjct: 397 RRHRPSPP 404
Score = 49.3 bits (116), Expect = 4e-05
Identities = 36/94 (38%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
Query: 23 PRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPSP 82
P R + S P RR S PPP SS P + RSPS R SP R R + SP
Sbjct: 619 PPPKRRASPSPPPKRRVSHSPPPKQRSS--PVTKRRSPSLSSKHRKGSSPSRSTREARSP 676
Query: 83 PRARRGSPSP-PRGRRLFPPGPAGFRGSSRGESR 115
+R SPSP PR + P RG+S R
Sbjct: 677 QPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQR 710
Score = 47.0 bits (110), Expect = 2e-04
Identities = 40/108 (37%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 15 PKDDGGGGPRSGRSSGSSSGPARRSSPPP---PPS-------GSSSRTPARRPRSPSGHR 64
PK P R S P +RSSP PS GSS R RSP +
Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN- 679
Query: 65 GRRASPSP-PRGRRVSPSPPRARRGSPSPPRGRRLFPPGPAGFRGSSR 111
+R SPSP PR + S SPP RRG+ S P+ R+ P R SR
Sbjct: 680 -KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726
Score = 46.6 bits (109), Expect = 3e-04
Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 23/141 (16%)
Query: 929 KKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKS 988
K RE G PLL+ I EL++E E +++Q E +K+A + K
Sbjct: 96 KNAREFMGELWPLLLSAQENIAGIPSAFLELKKE--EIKQRQIEQEKLASM-------KK 146
Query: 989 QKSLSDSREPTEKPG---KAEKSKSPEKVSSFSNSSSNKESKVNNEKFR----------- 1034
Q D R+ EK K E+S+SP + S S S + S V E+ R
Sbjct: 147 QDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTK 206
Query: 1035 TKSPKPAESPQSATKQLDQPT 1055
++SP PA + T +L +P+
Sbjct: 207 SRSPSPAPEKKEKTPELPEPS 227
Score = 46.6 bits (109), Expect = 3e-04
Identities = 46/147 (31%), Positives = 52/147 (35%), Gaps = 28/147 (19%)
Query: 11 SSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSG---SSSRTPARRPRSPSGHRGRR 67
S HR G P S P +R SP P P SSS P RR S S R +
Sbjct: 658 SKHRK----GSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQS 713
Query: 68 ASPSPPRGRRV-------------SPSPPRARR--------GSPSPPRGRRLFPPGPAGF 106
SPS RRV SPSP RR GSP P + PP P
Sbjct: 714 PSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQS 773
Query: 107 RGSSRGESRADYARDGRGDHPGDSGSR 133
+ S S A + + P S R
Sbjct: 774 QSPSTNWSPAVPVKKAKSPTPSPSPPR 800
Score = 42.7 bits (99), Expect = 0.004
Identities = 64/307 (20%), Positives = 106/307 (34%), Gaps = 47/307 (15%)
Query: 1191 ETERRRQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENK 1250
+ E+ + + +K++ +K K +K+EK++ K + K R+SP + E K
Sbjct: 135 QIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERK 194
Query: 1251 RNTGIKLQLKEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDG 1310
R+ + + + + SP PEK+E+ L PS+ +E
Sbjct: 195 RSHSRSPRHRTKSRSPSPA-----------PEKKEKTPELPEPSVKVKEPSVQEATSTSD 243
Query: 1311 KTEAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKP 1370
+ K +PI SP + K RP S ++ S + S
Sbjct: 244 ILKVPKPEPI-------PEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHT 296
Query: 1371 APLNTFLS-IKSSGTTAKPLPVVKES----SADLLLPPDIISKAFGG-------EEVILK 1418
P S +S +P P + S + +PP + L
Sbjct: 297 RPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLS 356
Query: 1419 GSPEEKVVLAEKSEPSHLPEQILPPP----------PPP-----PPPPPPPPPVIPHPAA 1463
GS +S P P++ PP PP P PP PPP H +
Sbjct: 357 GSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH--S 414
Query: 1464 PSAAQAN 1470
P+ Q+N
Sbjct: 415 PTPQQSN 421
Score = 42.0 bits (97), Expect = 0.007
Identities = 73/287 (25%), Positives = 101/287 (35%), Gaps = 40/287 (13%)
Query: 44 PPSGSSSRTPAR-RPRSPSGHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRLFPPG 102
P S S S++ +R R RSPS R RR S R P RR SP R PP
Sbjct: 276 PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPP 335
Query: 103 PAGFRGSSRGESRADYARDGRGDHPGDSGSRRRS-----PGLCSDSLEKSLRITVGNDHF 157
P R S R + G S SR RS P S K+ R++
Sbjct: 336 PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPS---- 391
Query: 158 CVSTPERRRLSDRLGSPVDNLEDMDRDDLTDDSVFTRSSQCS-------------RGLER 204
++P RRR R P S TR S+ S +G E+
Sbjct: 392 --ASPPRRR--HRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEK 447
Query: 205 YISQEEGPLSPFLGQLDEDYRTKETFLHRSDYSPHISCHDELLRGTERNREKLKGYSIRS 264
S P P +L E D ++ D + + + R+ + S
Sbjct: 448 RESPSPAP-KPRKVELSES---------EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSG 497
Query: 265 EERSREAKRPRYDDTVKINSMG--GDHPSFTSGTRNYRQRRRSPSPR 309
S E +RP+ VK +G H S + + R+R++ SPR
Sbjct: 498 SSSSSEDERPKRSH-VKNGEVGRRRRHSPSRSASPSPRKRQKETSPR 543
Score = 40.4 bits (93), Expect = 0.020
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 12 SHRPKDDGGGGPRSGRSSGSSSGPARRSSPPP-------PPSGSSSRTPARRPRSPSGHR 64
SH P P + R S S S R+ S P P + +P+ RPR+P
Sbjct: 636 SHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP---- 691
Query: 65 GRRASPSPPRGRRVSPSPPRARRGSPSP 92
+ S SPP RR + S P+ RR SPSP
Sbjct: 692 --QTSSSPPPVRRGASSSPQ-RRQSPSP 716
Score = 39.7 bits (91), Expect = 0.034
Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 3/98 (3%)
Query: 4 SSARSSVSSHRPKDDGGGGPRSGRS-SGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSG 62
SS+RS +P PR R S S+S P RR P PP + + P+ +
Sbjct: 363 SSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNR 422
Query: 63 HRGRRASPSPPR-GRRVSPSPPRARRGSPSP-PRGRRL 98
R R S SP R +V+ +R SPSP P+ R++
Sbjct: 423 TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV 460
Score = 38.5 bits (88), Expect = 0.076
Identities = 60/256 (23%), Positives = 89/256 (34%), Gaps = 37/256 (14%)
Query: 800 SRWPMYPTSQPSNHPVPEPHRIMPITKQATRSRPNLRVIPTVTPDKPKQKESLRGSIPAA 859
SR P + T S P PE K+ T P P+V +P +E+ S
Sbjct: 198 SRSPRHRTKSRSPSPAPEK-------KEKTPELPE----PSVKVKEPSVQEATSTS-DIL 245
Query: 860 QVPVQVSIPSLIRYNPEKISDEKNRASQKQKV-IEEREKLKNDREARQKKMYYLRTELER 918
+VP IP P++ S EKN +K+K R + ++ +R + T R
Sbjct: 246 KVPKPEPIPE-----PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR 300
Query: 919 LHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQ 978
H+ + +RR + R M R+ +++ A
Sbjct: 301 RHRSRSRSYSPRRRPSPRRRPS---PRRRTPPRRMPPPPRHRRSRSPVRRRRRSS---AS 354
Query: 979 ILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNSSSNKESKVNNEKFRTKSP 1038
+ G S S S SR P +KP K S P K S S+S R P
Sbjct: 355 LSG----SSSSSSSSRSRSPPKKPPK-RTSSPPRKTRRLSPSASPPR--------RRHRP 401
Query: 1039 KPAESPQSATKQLDQP 1054
P +P T+ P
Sbjct: 402 SPPATPPPKTRHSPTP 417
Score = 37.0 bits (84), Expect = 0.22
Identities = 60/248 (24%), Positives = 96/248 (38%), Gaps = 36/248 (14%)
Query: 668 RRSSDPHRLESREAHHSNTHSPEVSHPHPP----SPVDPYLLTKNSPPFLKSDHPVGHIS 723
RR++ P R A S VSH PP SPV TK P L S H G
Sbjct: 612 RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPV-----TKRRSPSLSSKHRKG--- 663
Query: 724 GPEVVGSGFQSSVAVRCMLPS---APSAPIRLPHTAALSQFHMPRASQFAAARIPPNYQG 780
S +S+ R P+ +PS R P T++ P + A+ P Q
Sbjct: 664 -----SSPSRSTREARSPQPNKRHSPSPRPRAPQTSS-----SPPPVRRGASSSPQRRQS 713
Query: 781 PAIPPASFDAYRHYMAYAASRWPMYPTSQPSNHPVPEPHRIMPITKQATRSRPNLRVIPT 840
P+ P++ R SR P + + P P+ R + ++ + S P
Sbjct: 714 PS--PSTRPIRR------VSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP 765
Query: 841 VTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKN 900
P + + PA VPV+ + +P + SD++ +K+K +++ K K+
Sbjct: 766 APPSPVQSQSPSTNWSPA--VPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHK-KD 822
Query: 901 DREARQKK 908
+ + KK
Sbjct: 823 KKHKKHKK 830
Score = 32.3 bits (72), Expect = 5.5
Identities = 57/284 (20%), Positives = 93/284 (32%), Gaps = 41/284 (14%)
Query: 1443 PPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPV 1502
P P PPP P P PS +P + +P + + SP P
Sbjct: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPS-----------PP 609
Query: 1503 AIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLAT 1562
+A P P +P R V PPP +++ + KR S +
Sbjct: 610 PKRRTASPPPPPKRRASPSPPPKRR------VSHSPPP------KQRSSPVTKRRSPSLS 657
Query: 1563 ANAKDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKSSDTSSTSP--LNS 1620
+ + KG+ ++ E + P N +S R ++ TSS+ P
Sbjct: 658 SKHR-----------KGSSPSRSTREAR---SPQPNKRHSPSPRPRAPQTSSSPPPVRRG 703
Query: 1621 SASQEELHQDEGLVAAPIVSNSEKPIAKTLVALGKWSVVEHVGPKSTGSTYGFLQPLTRL 1680
++S + Q PI S P K + S S+ S G +P +
Sbjct: 704 ASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKK 763
Query: 1681 --CQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSELDLG 1722
P ++ +P T+ +S T P S+ + G
Sbjct: 764 PPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGG 807
Score = 32.0 bits (71), Expect = 7.1
Identities = 88/438 (20%), Positives = 159/438 (36%), Gaps = 62/438 (14%)
Query: 1201 KRKLSEKPKEEKKEKKAK-AVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQL 1259
K + S P++ + +K++ +V + KV++ + +E R SP A R K++L
Sbjct: 410 KTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKH---KGTEKRESPSPAPKPR----KVEL 462
Query: 1260 KEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKP 1319
E + + ++ ++ + + + S S SS+D+ ++ +
Sbjct: 463 SESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS-----SSEDERPKRSHVKNGEV 517
Query: 1320 IKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSI 1379
+ + + A SP TS + + R + P T R+S S + P +
Sbjct: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSP--APPPRRRRTPTP 575
Query: 1380 KSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQ 1439
T P P + S PP + + PS P++
Sbjct: 576 PPRRRTPSPPPRRRSPSPRRYSPP-----------------------IQRRYSPSPPPKR 612
Query: 1440 ILPPPPPPPP----PPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVS---QTLSPGFVG 1492
PPPPP P PPP + H +P Q ++ + +S + S + SP
Sbjct: 613 RTASPPPPPKRRASPSPPPKRRVSH--SPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRST 670
Query: 1493 PNILNPVLPVAIMASAQPAAIPSDETAP----GVSESDRDQTLFSVLVRPPPPLSSVFSE 1548
+P S +P A + + P G S S + + S RP +S +
Sbjct: 671 REARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR--TP 728
Query: 1549 QAKKLEKRNSCLATANAKDLYDIFYSSGGKGAPE-----TKGAPETKLSGGPLANGENSN 1603
+ KK++K A+ + + + + S G+PE P S P N +
Sbjct: 729 EPKKIKK----AASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAV 784
Query: 1604 LSRTKSSDTSSTSPLNSS 1621
+ S T S SP +S
Sbjct: 785 PVKKAKSPTPSPSPPRNS 802
Score = 31.6 bits (70), Expect = 9.3
Identities = 31/176 (17%), Positives = 67/176 (38%), Gaps = 20/176 (11%)
Query: 875 PEKISDEKNRASQKQKVIEEREKLKNDREARQKKMYYLRTELERLHKQQGEMLRKKRREK 934
P +S ++N A +E +++ R+ Q+K+ ++ + E K+ E R ++
Sbjct: 107 PLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKR 166
Query: 935 DGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQKSLSD 994
+ + P + R E+K+S +S + +
Sbjct: 167 ERSRSPR-------RRKSRSPSPRRRSSPVRRERKRSH-------------SRSPRHRTK 206
Query: 995 SREPTEKPGKAEKSKSPEKVSSFSNSSSNKESKVNNEKFRTKSPKPAESPQSATKQ 1050
SR P+ P K EK+ + S S +E+ ++ + P+P P+ + +
Sbjct: 207 SRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPE 262
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 61.6 bits (148), Expect = 8e-09
Identities = 102/524 (19%), Positives = 214/524 (40%), Gaps = 64/524 (12%)
Query: 865 VSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKNDRE-ARQKKMYYLRTELERLHKQQ 923
V + + EK++ EK + + ++ +++ +++L+ + + A+++K L E++RL +++
Sbjct: 1917 VQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKA--LNLEMKRLAEEK 1974
Query: 924 GEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEA-----------EKKQSE 972
++ K G R + +++ E + EE E+ +
Sbjct: 1975 MRLVEGKETLSKGETPE--TSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIA 2032
Query: 973 LDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNSS---SNKESKVN 1029
K+ G IF + Q+ L+ + K + SK P K++ + + E K+
Sbjct: 2033 KGKLEFTRGQRIFVQGQRKLAKASRKLIKK-RESLSKEPAKLNKILKALQKLTRDERKLT 2091
Query: 1030 NEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHNK- 1088
E+ + K A + ++Q + +D F+ ++
Sbjct: 2092 QEEIKMTKMKRALFVKERRLSIEQSKLDIKEWD-------------------FSEKRSEL 2132
Query: 1089 -KHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPIS---GFYCQLCEEF 1144
K + L R A+K + ++ ++ + K SE ++ G + F
Sbjct: 2133 TKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPF 2192
Query: 1145 LGDPISGEQHVK-GHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSELKRK 1203
L + K G + EK+ VDE + E + L LE + SE
Sbjct: 2193 LKRRWRKRKEAKRGDKPKEKFSSQVDE--VESEEHFSEEMESLLDELEKQESLSSE---- 2246
Query: 1204 LSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEV 1263
E+ +EE++E++ + V+E +E+ K E+ E++ E +K + K ++Q KEEV
Sbjct: 2247 -EEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEV 2305
Query: 1264 KKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKE-EILESSK----DKEDGKTEAGKAK 1318
+E S + E+EEE+S + + +E EIL+ K ++ K+ G+ +
Sbjct: 2306 FEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365
Query: 1319 PIKI-------KLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIP 1355
+ I K + SP +++T+ + K + +P+P
Sbjct: 2366 VLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVP 2409
Score = 41.6 bits (96), Expect = 0.009
Identities = 33/166 (19%), Positives = 78/166 (46%), Gaps = 8/166 (4%)
Query: 817 EPHRIMPITKQATRSRPNLRVIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRY--N 874
E ++P K+ R R + DKPK+K S + ++ + SL+
Sbjct: 2185 EEEEVIPFLKRRWRKRKEAK-----RGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEK 2239
Query: 875 PEKISDEKNRASQKQKVIEEREKLKNDREARQKKMYYLRTELERLHKQQGEMLRKKRREK 934
E +S E+ ++++ EE E+++ + E R+++ ++E+ +++ + ++K++E+
Sbjct: 2240 QESLSSEEEEEREEEEEREE-EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE 2298
Query: 935 DGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQIL 980
K+ + E + + +E EE+ + E+D+ +IL
Sbjct: 2299 VQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEIL 2344
Score = 40.8 bits (94), Expect = 0.015
Identities = 39/182 (21%), Positives = 96/182 (52%), Gaps = 19/182 (10%)
Query: 871 IRYNPEKISDEKNRASQKQKV-IEEREKLKNDREARQKKMYYLRTELERLHKQQGEMLRK 929
+ + EK+S+E+ + +Q++++ I+E+EKL +E ++ L + E+L +++ ++ +K
Sbjct: 1756 LAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQK 1815
Query: 930 KRREKDGHKDPLLVEVSRLQ-DNIMKDIAELRQEAEE-AEKKQS-------------ELD 974
+ R + ++ ++ Q N+ ++ L QE E+ A++K++ +L
Sbjct: 1816 RERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLV 1875
Query: 975 KVAQILGI--NIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNSSSNKESKVNNEK 1032
+V LG+ I + ++ L+ +E K K + +++ +K+ +S + K+ K+ EK
Sbjct: 1876 QVKNKLGMFNKILAQVEEKLTQEKETVIKK-KEKLAETEKKLVQVEDSLAKKQEKLAQEK 1934
Query: 1033 FR 1034
+
Sbjct: 1935 MK 1936
Score = 38.5 bits (88), Expect = 0.076
Identities = 92/468 (19%), Positives = 181/468 (38%), Gaps = 66/468 (14%)
Query: 881 EKNRASQKQKVIEEREKLKNDREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDP 940
E+ A + +K+ +E EKL R+ KK + E E+L K+ G++ K
Sbjct: 1641 EETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQ----- 1695
Query: 941 LLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREPTE 1000
+ E+ + + N+ EL QE EE E EL + + + + + + E
Sbjct: 1696 KVEELPQREQNLDWQEKELAQELEELEWDMEELS----------WKEEELNQEEGKLVEE 1745
Query: 1001 KPGKAEKSKS----PEKVSSFSNSSSNKESKVNNEKFRT---KSPKPAESPQSATKQLDQ 1053
K AE+ ++ EK+S + +E + EK + K P E + K+
Sbjct: 1746 KKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL 1805
Query: 1054 PTAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDA 1113
+ W + + +K + N + ++ K++
Sbjct: 1806 IEKKMKLAQKRERWINSMEELTKNKMILY-----QKKNLAQEKKNLAQEKEKLAQRKENL 1860
Query: 1114 IKRTDKITVPAKGSEFLVPISGFYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVDENPL 1173
+ +++T K + G + K V+E
Sbjct: 1861 LYNKERLTHSKKQLVQVKNKLGMF------------------------NKILAQVEEKLT 1896
Query: 1174 YEERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKL 1233
E+ + ++ LA ETE ++ +++ L++K ++ +EK A+++ K ++L
Sbjct: 1897 QEKETVIKKKEKLA---ETE-KKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGK--KRL 1950
Query: 1234 EDQLSEGRNSPEKA---ENKRNTGIKLQL---KEEVKK-ESPTSSSFGKFSWKKPEKEEE 1286
+L + EKA E KR K++L KE + K E+P +S K + + E E
Sbjct: 1951 RGELDIAKE--EKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFER 2008
Query: 1287 KSSLVTPSISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHTS 1334
K SL + E+ + + ++ E K + + +I + G+ +A S
Sbjct: 2009 KLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKAS 2056
>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapiens]
Length = 678
Score = 60.5 bits (145), Expect = 2e-08
Identities = 75/297 (25%), Positives = 119/297 (40%), Gaps = 36/297 (12%)
Query: 1402 PPDIISKAFGGEEVILKGSPEEKVV-LAEKSEPSHLP------EQILPPPPPPPPPPPPP 1454
PP + EV++ G+P +V L E+ +P P E+ PPPPPPPP PP P
Sbjct: 49 PPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRP 108
Query: 1455 PPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGF-VGPNILNPVLPVAIMASA----Q 1509
PP P P A + + + + +T S F V P L+ ++++ +
Sbjct: 109 PPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPE 168
Query: 1510 PAAIPSDETA---PGVSESDRDQTLFSVLVRPPP----PLSSVFSEQAKKLEKRNSCLAT 1562
P A P++ A PG + + PPP P ++ S A + C++
Sbjct: 169 PRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSA 228
Query: 1563 A-NAKDLYDIFYSSGGKGAPET--KGAPETKLSGGPLANGENSNLSRTKSSDTSSTSPLN 1619
A + D ++I K ET G + + AN NS + KS +S +P
Sbjct: 229 ATSTNDSFEI--RPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSK--ASGAPPP 284
Query: 1620 SSASQEELHQDEGLVAAPIVSNSEKPI--AKTLVALGK--------WSVVEHVGPKS 1666
EL + + A+P +P+ ALGK W+V E P++
Sbjct: 285 EGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRT 341
Score = 37.7 bits (86), Expect = 0.13
Identities = 39/118 (33%), Positives = 42/118 (35%), Gaps = 28/118 (23%)
Query: 23 PRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPR--GRRVSP 80
P + R GS P R PPPPP P PR P A+PSPP G R
Sbjct: 82 PAAPRRRGS---PERARPPPPPP-------PPAPPRPPP------AAPSPPAAPGPRGGG 125
Query: 81 SPPRARRGSPSPPRGRRLFPPGPAGF----------RGSSRGESRADYARDGRGDHPG 128
+ P ARR G F P G G S E RA A G PG
Sbjct: 126 ASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPG 183
Score = 32.7 bits (73), Expect = 4.2
Identities = 37/120 (30%), Positives = 48/120 (40%), Gaps = 24/120 (20%)
Query: 41 PPPPPSGSSSRTPARRPR---SPSGHRGRRASP-SPPRGRRVSPSPPRARRGSPSPPRGR 96
PP PP+ +++ A +P G R PP R SP RAR P PP
Sbjct: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
Query: 97 RLFP---------PGPAGFRGSSRGESRADYAR---------DGRGDHPGDSGSRRRSPG 138
P PGP G G+S G R+D+ + RG H G +G+R S G
Sbjct: 106 PRPPPAAPSPPAAPGPRG-GGASPGARRSDFLQKTGSNSFTVHPRGLHRG-AGARLLSNG 163
>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapiens]
Length = 650
Score = 60.5 bits (145), Expect = 2e-08
Identities = 75/297 (25%), Positives = 119/297 (40%), Gaps = 36/297 (12%)
Query: 1402 PPDIISKAFGGEEVILKGSPEEKVV-LAEKSEPSHLP------EQILPPPPPPPPPPPPP 1454
PP + EV++ G+P +V L E+ +P P E+ PPPPPPPP PP P
Sbjct: 49 PPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRP 108
Query: 1455 PPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGF-VGPNILNPVLPVAIMASA----Q 1509
PP P P A + + + + +T S F V P L+ ++++ +
Sbjct: 109 PPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPE 168
Query: 1510 PAAIPSDETA---PGVSESDRDQTLFSVLVRPPP----PLSSVFSEQAKKLEKRNSCLAT 1562
P A P++ A PG + + PPP P ++ S A + C++
Sbjct: 169 PRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSA 228
Query: 1563 A-NAKDLYDIFYSSGGKGAPET--KGAPETKLSGGPLANGENSNLSRTKSSDTSSTSPLN 1619
A + D ++I K ET G + + AN NS + KS +S +P
Sbjct: 229 ATSTNDSFEI--RPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSK--ASGAPPP 284
Query: 1620 SSASQEELHQDEGLVAAPIVSNSEKPI--AKTLVALGK--------WSVVEHVGPKS 1666
EL + + A+P +P+ ALGK W+V E P++
Sbjct: 285 EGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRT 341
Score = 37.7 bits (86), Expect = 0.13
Identities = 39/118 (33%), Positives = 42/118 (35%), Gaps = 28/118 (23%)
Query: 23 PRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPR--GRRVSP 80
P + R GS P R PPPPP P PR P A+PSPP G R
Sbjct: 82 PAAPRRRGS---PERARPPPPPP-------PPAPPRPPP------AAPSPPAAPGPRGGG 125
Query: 81 SPPRARRGSPSPPRGRRLFPPGPAGF----------RGSSRGESRADYARDGRGDHPG 128
+ P ARR G F P G G S E RA A G PG
Sbjct: 126 ASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPG 183
Score = 32.7 bits (73), Expect = 4.2
Identities = 37/120 (30%), Positives = 48/120 (40%), Gaps = 24/120 (20%)
Query: 41 PPPPPSGSSSRTPARRPR---SPSGHRGRRASP-SPPRGRRVSPSPPRARRGSPSPPRGR 96
PP PP+ +++ A +P G R PP R SP RAR P PP
Sbjct: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
Query: 97 RLFP---------PGPAGFRGSSRGESRADYAR---------DGRGDHPGDSGSRRRSPG 138
P PGP G G+S G R+D+ + RG H G +G+R S G
Sbjct: 106 PRPPPAAPSPPAAPGPRG-GGASPGARRSDFLQKTGSNSFTVHPRGLHRG-AGARLLSNG 163
>gi|40807465 zinc finger protein 341 [Homo sapiens]
Length = 847
Score = 59.3 bits (142), Expect = 4e-08
Identities = 42/144 (29%), Positives = 66/144 (45%), Gaps = 19/144 (13%)
Query: 1337 MPVVTTSTQTKIRPNLPIPSTVLRKSCS---------ATMSKPAPLNTFLSIKSSGTTAK 1387
+P T + + + N P +TV + S A P P N +S + T
Sbjct: 65 LPAFMTHKREQCQGNAPALATVSLATNSIYPPSAAPTAVQQAPTPANRQIS---TYITVP 121
Query: 1388 PLPVVKES-SADLLLPPDIISKAFGG----EEVILKGSPEEKVVLAEKSEPSHLPEQILP 1442
P P+++ ++L+ D++ A ++ + +G P + L S PS+L + P
Sbjct: 122 PSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPPPVQSSLNMHSVPSYLTQP--P 179
Query: 1443 PPPPPPPPPPPPPPVIPHPAAPSA 1466
PPPPPPPP PPPPP P P P +
Sbjct: 180 PPPPPPPPLPPPPPPQPPPPPPQS 203
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 58.9 bits (141), Expect = 5e-08
Identities = 105/493 (21%), Positives = 181/493 (36%), Gaps = 55/493 (11%)
Query: 873 YNPEKISDEKNRASQKQKVIEEREKLKNDREARQKKMYYLRTELERLHKQQGEMLRKKRR 932
+ P S + + + V + R+ + ++E R + R +LE KQ+ E + +
Sbjct: 472 HKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKT 531
Query: 933 EKDGH---------------KDPLLVEVSRLQDNIMKDIA-------ELRQEAEEAEKKQ 970
+ G K + EV + + + K +A + R E ++KKQ
Sbjct: 532 KGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQ 591
Query: 971 SELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSN--SSSNKESKV 1028
+ + L + + +K +S S+E K+E SK ++S + + ESK+
Sbjct: 592 QYEEDSKETLKTSEHCEKEK-ISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKL 650
Query: 1029 NNE-KFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHN 1087
E K RT +P E Q T D K +T+ N
Sbjct: 651 EREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTL-----------KN 699
Query: 1088 KKHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQLCEEFLGD 1147
+KH + D S + E K K + T SE + + Y C GD
Sbjct: 700 EKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTP----SEDKLSVKHKYKGDCMHKTGD 755
Query: 1148 PISGEQHVKGHQHNEKYKKYVDENPLYE----ERRNLDRQAGLAVVLETERRRQSELKRK 1203
KG + E +K + L ER++ R VL + + SE K
Sbjct: 756 ETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIK 815
Query: 1204 LSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEV 1263
E ++E +K+ + E + + S + D + + + + GI LQ + E
Sbjct: 816 TDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQ-----KDSLGSKQHGITLQRRSES 870
Query: 1264 KKESPTS-SSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPIKI 1322
E S S KPE+ K T S+ +E+++ SK K GK + K ++
Sbjct: 871 YSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGK----QVKVVET 926
Query: 1323 KLSGKTVVAHTSP 1335
+L T+P
Sbjct: 927 ELQEGATKQATTP 939
Score = 48.1 bits (113), Expect = 1e-04
Identities = 88/475 (18%), Positives = 166/475 (34%), Gaps = 72/475 (15%)
Query: 1431 SEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPSAAQANA------------------- 1471
+ P P PPPPPP P P PPPP A P A A
Sbjct: 3 TNPQPQPPPPAPPPPPPQPQPQPPPPPPGPGAGPGAGGAGGAGAGAGDPQLVAMIVNHLK 62
Query: 1472 -----------ILAPVKSNPVVSQTLS--PGFVGPNILNPVLPVAIMASAQPAAIPSDET 1518
LA V + P FV ++ + + I
Sbjct: 63 SQGLFDQFRRDCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVL 122
Query: 1519 APGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGK 1578
G+ ES D+ + V+ P ++ F Q +K + LAT N K+ G
Sbjct: 123 KSGMLESGIDRIISQVV---DPKINHTFRPQVEKAV--HEFLATLNHKE------EGSGN 171
Query: 1579 GAPETKGAPETKLSGGPLANGENSNLSRTKSSDTSSTSPLNSSASQEELHQDEGLVAAPI 1638
AP+ + + ++ G G ++N++ S + + LN AS +
Sbjct: 172 TAPDDEKPDTSLITQGVPTPGPSANVANDAMSILETITSLNQEASAARASTETSNAKTSE 231
Query: 1639 VSNSEKPIAKTL-VALGKWSVVEHVGPKSTGSTYGFLQPLTRLCQSRPYETITPKTDTLA 1697
++ + P T + K E + K + + L +S + + + +
Sbjct: 232 RASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIK 291
Query: 1698 IWTSSS-----FQSDTSRDISPEKSE-LDLGEPGPPGVEPPPQLLDIQCKESQKLVEIHL 1751
+T D ++ S +K++ D GE P E + + + K +K
Sbjct: 292 NYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKF----- 346
Query: 1752 RESVNQDKESQELRKSEDCRESEIET-------NTELKERVKELSE--GIVDEGVS--TS 1800
+ + +++Q+++ + +E E+E+ N+ + V+ E ++D V T
Sbjct: 347 -DHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTD 405
Query: 1801 IGPHSIDDSNLNH-----GNRYMWEGEVKQPNLLMIDKEAEQSNKLMTGSETPSK 1850
I S+ S+L+ + +++ + D+E + NK T + S+
Sbjct: 406 ITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSE 460
Score = 47.0 bits (110), Expect = 2e-04
Identities = 75/406 (18%), Positives = 163/406 (40%), Gaps = 58/406 (14%)
Query: 895 REKLKNDREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMK 954
++++K+ +E +++ +L HK +G+ + K E + H ++V ++NI K
Sbjct: 718 KKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKV---EENIQK 774
Query: 955 DIAELRQEAEEAEKKQSEL--DKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPE 1012
+ + +++ +++S+ ++ +LG + S+ + ++ K E+ S E
Sbjct: 775 QSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAE 834
Query: 1013 KVSSFSNSSSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCN 1072
K + S + +SK+ + +K +S + D+ C +
Sbjct: 835 KTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDK--------------CDMDS 880
Query: 1073 TICGTMFDFFTHMHN-KKHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLV 1131
T + +H K+ T++L SK++++ KQ + T+ K +
Sbjct: 881 TNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPK 940
Query: 1132 PISGFYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLE 1191
P E++ + + ++ K V++ P E G+ VLE
Sbjct: 941 P-----------------DKEKNTEENDSEKQRKSKVEDKPFEE--------TGVEPVLE 975
Query: 1192 TERRRQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKR 1251
T ++ S + K ++K K+ K D S +LE +LS+G K+ + +
Sbjct: 976 TASSSAHSTQKDSSHRAKLPLAKEKYKSDK-----DSTSTRLERKLSDG----HKSRSLK 1026
Query: 1252 NTGIKLQLKEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISK 1297
++ ++ K+E K + GK EK SSL+ +S+
Sbjct: 1027 HSSKDIKKKDENKSDDKD----GKEVDSSHEKARGNSSLMEKKLSR 1068
Score = 32.7 bits (73), Expect = 4.2
Identities = 33/121 (27%), Positives = 57/121 (47%), Gaps = 18/121 (14%)
Query: 1204 LSEKPKEEKKEKKAKAVKEVKEDDK-------VSEKLEDQLSEGRN-SPEKAENKRNTGI 1255
L PK E+ V+E+K K +++ ++ + SE +N S +K E K ++
Sbjct: 271 LETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNE 330
Query: 1256 KLQLKEEVKKE-------SPTSSSFGKFSWKKPEKEEEKSSLVTPS---ISKEEILESSK 1305
K + K+E K++ S S K +K KE+E SL PS +K + +E +K
Sbjct: 331 KGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTK 390
Query: 1306 D 1306
+
Sbjct: 391 E 391
Score = 32.3 bits (72), Expect = 5.5
Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 3/61 (4%)
Query: 515 ADSTSTQEKRRRSFPDIEDEEKFLYGDEEEDLKAESVPK---PLGSSESEVMRQKASSLP 571
A+S+ + KR++S D +++K DEEE+ + E P ++ SE R K P
Sbjct: 2961 AESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQRSKTQLSP 3020
Query: 572 S 572
S
Sbjct: 3021 S 3021
Score = 32.0 bits (71), Expect = 7.1
Identities = 36/163 (22%), Positives = 67/163 (41%), Gaps = 24/163 (14%)
Query: 1152 EQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEE 1211
+ + KG + EK +K E +++ D Q + + +Q++ K S K E
Sbjct: 327 DSNEKGERKKEKKEK--TEKKFDHSKKSEDTQ-------KVKDEKQAKEKEVESLKLPSE 377
Query: 1212 KKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEVKKESPTSS 1271
K KAK V+ KED + + D L+ + + +T +E+ ++E TS
Sbjct: 378 KNSNKAKTVEGTKEDFSLIDSDVDGLT------DITVSSVHTSDLSSFEEDTEEEVVTSD 431
Query: 1272 SFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEA 1314
S + ++E+ K + S D +GKT++
Sbjct: 432 SMEEGEITSDDEEKNKQNKTKTQTS---------DSSEGKTKS 465
>gi|116256475 zinc finger protein 827 [Homo sapiens]
Length = 1077
Score = 58.5 bits (140), Expect = 7e-08
Identities = 39/114 (34%), Positives = 53/114 (46%), Gaps = 15/114 (13%)
Query: 1343 STQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLP 1402
S+Q+ + V +S + P P ++FLS+ S ++A L V +A LL
Sbjct: 245 SSQSASSTLAALSKKVSERSLTPGQEHPPPASSFLSLASMTSSAALLKEVAARAAGSLLA 304
Query: 1403 PDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPPPPP 1456
K+ E L P EK PE++ PPPPPPPPPPPPPPP
Sbjct: 305 ----EKSSLLPEDPLPPPPSEKK-----------PEKVTPPPPPPPPPPPPPPP 343
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 57.8 bits (138), Expect = 1e-07
Identities = 119/543 (21%), Positives = 186/543 (34%), Gaps = 86/543 (15%)
Query: 1264 KKESPTSSSFGKFSWKKPEKEEEKSSLVT------PSISKEEILESSKD------KEDGK 1311
K+ +PT+ + K+P K T P+ KE ++K+ KE
Sbjct: 331 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390
Query: 1312 TEAGKAKPIKIKLSGKTVV--AHTSPWMPVVTTSTQ-TKIRPNLPIPSTVLRKSCSATMS 1368
T K+ P K T A T+P P TT+ + P P P+T +K T
Sbjct: 391 TTT-KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPK 448
Query: 1369 KPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLA 1428
+PAP T + TT KP P + A P A + + +PE+
Sbjct: 449 EPAP--TTPKEPAPTTTKKPAPTTPKEPA----PTTPKETAPTTPKKLTPTTPEKLAPTT 502
Query: 1429 EKSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSP 1488
+ PE++ P P P P P P P P AA N P + P +P
Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPA---PTTPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 1489 GFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSE 1548
+PA ETAP + TL + P P ++
Sbjct: 560 -------------------KEPAPTTPKETAPTTPKGTAPTTL-----KEPAP-TTPKKP 594
Query: 1549 QAKKLEKRNSCLATANAKDLYDIFYSSGGKGAPET-KG-APETKLSGGPLANGENSNLSR 1606
K+L + T+ D K AP T KG AP T P E + +
Sbjct: 595 APKELAPTTTKEPTSTTCD----------KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 644
Query: 1607 TKSSDTSSTSPLNSSASQEELHQ-DEGLVAAPIVSNSEKPIAKTLVALGKWSVVEHVGPK 1665
++ T+ P ++ + + P + S+KP T PK
Sbjct: 645 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT--------------PK 690
Query: 1666 STGSTYGFLQPLTRLCQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSELDL-GEP 1724
T T T + P TP T + T ++ + T+ SP++S +L EP
Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 750
Query: 1725 GPPGVEPPPQLLDIQCKESQKLVEIHLRESVNQDKESQELRKSEDCRESEIETNTELKER 1784
P +E P+ + ++ + + + ++LR + ET T +
Sbjct: 751 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-------ETTTAAPKM 803
Query: 1785 VKE 1787
KE
Sbjct: 804 TKE 806
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 57.8 bits (138), Expect = 1e-07
Identities = 119/543 (21%), Positives = 186/543 (34%), Gaps = 86/543 (15%)
Query: 1264 KKESPTSSSFGKFSWKKPEKEEEKSSLVT------PSISKEEILESSKD------KEDGK 1311
K+ +PT+ + K+P K T P+ KE ++K+ KE
Sbjct: 372 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431
Query: 1312 TEAGKAKPIKIKLSGKTVV--AHTSPWMPVVTTSTQ-TKIRPNLPIPSTVLRKSCSATMS 1368
T K+ P K T A T+P P TT+ + P P P+T +K T
Sbjct: 432 TTT-KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPK 489
Query: 1369 KPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLA 1428
+PAP T + TT KP P + A P A + + +PE+
Sbjct: 490 EPAP--TTPKEPAPTTTKKPAPTTPKEPA----PTTPKETAPTTPKKLTPTTPEKLAPTT 543
Query: 1429 EKSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSP 1488
+ PE++ P P P P P P P P AA N P + P +P
Sbjct: 544 PEKPAPTTPEELAPTTPEEPTPTTPEEPA---PTTPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 1489 GFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSE 1548
+PA ETAP + TL + P P ++
Sbjct: 601 -------------------KEPAPTTPKETAPTTPKGTAPTTL-----KEPAP-TTPKKP 635
Query: 1549 QAKKLEKRNSCLATANAKDLYDIFYSSGGKGAPET-KG-APETKLSGGPLANGENSNLSR 1606
K+L + T+ D K AP T KG AP T P E + +
Sbjct: 636 APKELAPTTTKEPTSTTCD----------KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 685
Query: 1607 TKSSDTSSTSPLNSSASQEELHQ-DEGLVAAPIVSNSEKPIAKTLVALGKWSVVEHVGPK 1665
++ T+ P ++ + + P + S+KP T PK
Sbjct: 686 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT--------------PK 731
Query: 1666 STGSTYGFLQPLTRLCQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSELDL-GEP 1724
T T T + P TP T + T ++ + T+ SP++S +L EP
Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 791
Query: 1725 GPPGVEPPPQLLDIQCKESQKLVEIHLRESVNQDKESQELRKSEDCRESEIETNTELKER 1784
P +E P+ + ++ + + + ++LR + ET T +
Sbjct: 792 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-------ETTTAAPKM 844
Query: 1785 VKE 1787
KE
Sbjct: 845 TKE 847
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 57.4 bits (137), Expect = 2e-07
Identities = 105/480 (21%), Positives = 183/480 (38%), Gaps = 77/480 (16%)
Query: 1161 NEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQ-----SELKRKLSEKPKEEKKEK 1215
NE YK V + Y R +Q + ++++Q S+ ++ EK KE +KE+
Sbjct: 476 NENYKSLVRRS--YRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEE 533
Query: 1216 KAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEVKKESPTSSSFGK 1275
+ V+ KE D + EK +D E + E +K Q + + + ++
Sbjct: 534 EKPEVENDKE-DLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANS 592
Query: 1276 FSWKKPEKEEEKSSLVTPSISK--EEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHT 1333
P++ E +S+ S+ EE +E++K G E G+ ++ G V+
Sbjct: 593 EEAITPQQSAELASMELNESSRWTEEEMETAK---KGLLEHGRNWSAIARMVGSKTVSQC 649
Query: 1334 SPW-------MPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPA---PLNTFLSIKSSG 1383
+ + Q K++ + +K A S+ A P+ +++SG
Sbjct: 650 KNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASG 709
Query: 1384 TTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPP 1443
+ +V+E+ E + S + + + + +E + Q P
Sbjct: 710 VSGNEEEMVEEA------------------EATVNNSSDTESIPSPHTEAAKDTGQNGPK 751
Query: 1444 PP-------PPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNIL 1496
PP PPP PP PPP IP P P+ A S + T P P+
Sbjct: 752 PPATLGADGPPPGPPTPPPEDIPAPTEPTPA----------SEATGAPTPPPAPPSPSAP 801
Query: 1497 NPVLPVAIMASAQPAAIP---SDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKK- 1552
PV+P AA P +E P +E T + P+ S +E+A++
Sbjct: 802 PPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDT-----GKAEEPVKSECTEEAEEG 856
Query: 1553 -LEKRNSCLATANAKDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKSSD 1611
+ +++ A A A+ GG G T K SG P ++S+ S T S+D
Sbjct: 857 PAKGKDAEAAEATAEGALKAEKKEGGSGRATT-----AKSSGAP----QDSDSSATCSAD 907
Score = 34.3 bits (77), Expect = 1.4
Identities = 123/616 (19%), Positives = 198/616 (32%), Gaps = 128/616 (20%)
Query: 1208 PKEEKKEKKAKAVKEVKED---------DKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQ 1258
P EE +E+K A +E+ D + +E+ E+ ++G+++ E AE +K +
Sbjct: 819 PVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDA-EAAEATAEGALKAE 877
Query: 1259 LKEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSK----------DKE 1308
KE + T+ S G P+ + ++ + + E + ++
Sbjct: 878 KKEGGSGRATTAKSSGA-----PQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTG 932
Query: 1309 DGKTEAGKAKPIKIKLSGKTVVAH-----TSPWMPVVTTSTQTKIRPNLPIPSTVLRKSC 1363
D + A KP+ +K + A T P + TK P P P L+
Sbjct: 933 DPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPES 992
Query: 1364 SATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPE- 1422
A P S + + P P KE+ + P AF E L G P
Sbjct: 993 DA------PQQPGSSPRGKSRSPAP-PADKEAEKPVFFP------AFAAEAQKLPGDPPC 1039
Query: 1423 -----------EKVVLAEKSEPSHLPEQILPPPPP--------------PPPPPPPPPPV 1457
+V+ A P PP P PP PPP+
Sbjct: 1040 WTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPL 1099
Query: 1458 IPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDE 1517
I PS + + +SQ +S P + PV + P + +
Sbjct: 1100 ISSAKHPSVLE--------RQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKK 1151
Query: 1518 TAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGG 1577
AP S ++Q PP L +++A L R + L +
Sbjct: 1152 LAP-FSGVKQEQLSPRGQAGPPESLGVPTAQEASVL--RGTALGSV-------------- 1194
Query: 1578 KGAPETKGAPETKLSGGPLANGENSNLSRTKS----SDTSSTSPLNSSASQEELHQDEGL 1633
G TKG P T++ S T + T + S S+ + +++ L
Sbjct: 1195 PGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSL 1254
Query: 1634 VAAPIVSNSEKPIAKTLVALGKWSVVEHVGPKSTGSTYGFLQPLTRLCQSRPYETITPKT 1693
++ +K L G SV + K G R P+ET PK
Sbjct: 1255 PKGHVIYEGKK--GHVLSYEGGMSVTQ--CSKEDG----------RSSSGPPHETAAPKR 1300
Query: 1694 DTLAIWTSSSFQSDTSRDISPEKSELDLGEPGPPGVEPPPQLLDIQCKESQKLVEIHLRE 1753
T + R IS E +G PP P L + + H+R
Sbjct: 1301 ------TYDMMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKE----------QHHIRG 1344
Query: 1754 SVNQDKESQELRKSED 1769
S+ Q + ED
Sbjct: 1345 SITQGIPRSYVEAQED 1360
Score = 33.1 bits (74), Expect = 3.2
Identities = 21/92 (22%), Positives = 31/92 (33%), Gaps = 9/92 (9%)
Query: 16 KDDGGGGPRSGRSSGSSSGPARRSSPP---------PPPSGSSSRTPARRPRSPSGHRGR 66
KD G GP+ + G+ P +PP P P+ ++ P P PS
Sbjct: 743 KDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPP 802
Query: 67 RASPSPPRGRRVSPSPPRARRGSPSPPRGRRL 98
P + + +PP PP L
Sbjct: 803 PVVPKEEKEEETAAAPPVEEGEEQKPPAAEEL 834
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 57.0 bits (136), Expect = 2e-07
Identities = 137/680 (20%), Positives = 237/680 (34%), Gaps = 99/680 (14%)
Query: 828 ATRSRPNLRVIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQ 887
++ SR R++ K K + + G + + I L+ Y+ + SD +
Sbjct: 29 SSNSRERHRLVSKHKRHKSKHSKDM-GLVTPEAASLGTVIKPLVEYD-DISSDSDTFSDD 86
Query: 888 KQKVIEEREKLKNDREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSR 947
++ RE ND + L H++ ++L+ K+ EK+ ++ + +
Sbjct: 87 MAFKLDRRE---NDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQE-VSSKSGS 142
Query: 948 LQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEK 1007
++D I +E ++ K Q + S K S+ EK K +
Sbjct: 143 MKDRISGSSKRSNEETDDYGKAQ-------------VAKSSSKESRSSKLHKEKTRKERE 189
Query: 1008 SKSPEKVSSFSN---SSSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAA-----YE 1059
KS K S S+ + V++ K R++SP S S KQ D P+ A Y+
Sbjct: 190 LKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSS--KQDDSPSGASYGQDYD 247
Query: 1060 YYDAGNHWCKDCNTICGTMFDFFTHM--HNKKHTQTLDPYNRPWASKTQSEAKQDAIKRT 1117
+ +H + +D + + PY P A ++ + + +R
Sbjct: 248 LSPSRSHTSSN--------YDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQ 299
Query: 1118 DKITVPAKGSEFLVPISGFYC----------QLCEEFLG------DPISGEQHVKGHQHN 1161
++ ++ SG Y + FL P+ + +K +
Sbjct: 300 RSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRS 359
Query: 1162 EKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKAVK 1221
Y ++ + + + R + ++ V S L +LS K KE +A A
Sbjct: 360 PAYSRHSSSHSKKKRSSSRSRHSSISPV---RLPLNSSLGAELSRKKKE-----RAAAAA 411
Query: 1222 EVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEVKKESPTSSSFGKFSWKKP 1281
K D K S+ L NS +A++ KL +++K +P +
Sbjct: 412 AAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNT- 470
Query: 1282 EKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKT------------- 1328
E K+S T + +E E K+ +KPI +K T
Sbjct: 471 ---EVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPP 527
Query: 1329 ---VVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGTT 1385
+A P +P T QT P LP P L + S+PA F + +S T+
Sbjct: 528 PLPTIASPPPPLPTTTPPPQTPPLPPLP-PIPALPQQPPLPPSQPA----FSQVPASSTS 582
Query: 1386 AKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPP 1445
P ++SA + S+A V + + V A HL LPP P
Sbjct: 583 TLPPSTHSKTSA-------VSSQANSQPPVQVSVKTQVSVTAAIP----HLKTSTLPPLP 631
Query: 1446 PPPPPPPPPPPVIPHPAAPS 1465
PP P P PS
Sbjct: 632 LPPLLPGDDDMDSPKETLPS 651
Score = 47.0 bits (110), Expect = 2e-04
Identities = 66/303 (21%), Positives = 110/303 (36%), Gaps = 56/303 (18%)
Query: 1281 PEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHTSPWMPVV 1340
P ++ KS +P+ S+ S K + ++ P+++ L+ +
Sbjct: 348 PSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERA 407
Query: 1341 TTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGTTAKPLP---------- 1390
+ K+ ++S + + P N+ + K SG +K LP
Sbjct: 408 AAAAAAKMDG---------KESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAP 458
Query: 1391 ------------VVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVL----------- 1427
VK SS + D S+ +++ +G+ + K +
Sbjct: 459 DTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKET 518
Query: 1428 --AEKSEPSHLPEQILPPPPPP----PPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPV 1481
+EK P LP PPPP P PP PP PP+ P PA P L P S P
Sbjct: 519 ETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPP----LPP--SQPA 572
Query: 1482 VSQ--TLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPP 1539
SQ S + P+ + V+ A++QP S +T V+ + ++ P
Sbjct: 573 FSQVPASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPL 632
Query: 1540 PPL 1542
PPL
Sbjct: 633 PPL 635
Score = 42.7 bits (99), Expect = 0.004
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 9/45 (20%)
Query: 1442 PPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTL 1486
PP PP PPPPPPPPP++ + + AP + NP V+ L
Sbjct: 1257 PPEPPGPPPPPPPPPLV---------EGDLSSAPQELNPAVTAAL 1292
Score = 37.7 bits (86), Expect = 0.13
Identities = 59/190 (31%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query: 4 SSARSSVSSHRP------KDDGGGGPRSG--------RSSGSSSGPARRSSPPPPPSGSS 49
S R S S HR +DD G G RS SS+ + + SP GS+
Sbjct: 215 SPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSP-----GST 269
Query: 50 SRTPARRP--RSPSGHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRL-FPPGPAG- 105
SR + P + PS ++ SPSP R+ S SP RR S G P P G
Sbjct: 270 SRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGR 329
Query: 106 FRGSSRGESRADYARDGRGDHPGDSGSRRRSPGLC--SDSLEKSLRITVGNDHFCVSTPE 163
R SS S+ +R SR RSP S S K R + + H +S P
Sbjct: 330 RRSSSPFLSKRSLSRSPLPSRK-SMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSIS-PV 387
Query: 164 RRRLSDRLGS 173
R L+ LG+
Sbjct: 388 RLPLNSSLGA 397
Score = 34.3 bits (77), Expect = 1.4
Identities = 26/106 (24%), Positives = 43/106 (40%), Gaps = 16/106 (15%)
Query: 1347 KIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGT--TAKPLPVVKESSADLLLPPD 1404
K P+ P+ ++ S PA + L++ S T +P ++E+++D P
Sbjct: 1180 KEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGP- 1238
Query: 1405 IISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPPPPPPP 1450
+G + E++ PE PPPPPPPPP
Sbjct: 1239 -------------QGPRRTPTMPQEEAAEKRPPEPPGPPPPPPPPP 1271
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 57.0 bits (136), Expect = 2e-07
Identities = 137/680 (20%), Positives = 237/680 (34%), Gaps = 99/680 (14%)
Query: 828 ATRSRPNLRVIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQ 887
++ SR R++ K K + + G + + I L+ Y+ + SD +
Sbjct: 29 SSNSRERHRLVSKHKRHKSKHSKDM-GLVTPEAASLGTVIKPLVEYD-DISSDSDTFSDD 86
Query: 888 KQKVIEEREKLKNDREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSR 947
++ RE ND + L H++ ++L+ K+ EK+ ++ + +
Sbjct: 87 MAFKLDRRE---NDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQE-VSSKSGS 142
Query: 948 LQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEK 1007
++D I +E ++ K Q + S K S+ EK K +
Sbjct: 143 MKDRISGSSKRSNEETDDYGKAQ-------------VAKSSSKESRSSKLHKEKTRKERE 189
Query: 1008 SKSPEKVSSFSN---SSSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAA-----YE 1059
KS K S S+ + V++ K R++SP S S KQ D P+ A Y+
Sbjct: 190 LKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSS--KQDDSPSGASYGQDYD 247
Query: 1060 YYDAGNHWCKDCNTICGTMFDFFTHM--HNKKHTQTLDPYNRPWASKTQSEAKQDAIKRT 1117
+ +H + +D + + PY P A ++ + + +R
Sbjct: 248 LSPSRSHTSSN--------YDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQ 299
Query: 1118 DKITVPAKGSEFLVPISGFYC----------QLCEEFLG------DPISGEQHVKGHQHN 1161
++ ++ SG Y + FL P+ + +K +
Sbjct: 300 RSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRS 359
Query: 1162 EKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKAVK 1221
Y ++ + + + R + ++ V S L +LS K KE +A A
Sbjct: 360 PAYSRHSSSHSKKKRSSSRSRHSSISPV---RLPLNSSLGAELSRKKKE-----RAAAAA 411
Query: 1222 EVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEVKKESPTSSSFGKFSWKKP 1281
K D K S+ L NS +A++ KL +++K +P +
Sbjct: 412 AAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNT- 470
Query: 1282 EKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKT------------- 1328
E K+S T + +E E K+ +KPI +K T
Sbjct: 471 ---EVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPP 527
Query: 1329 ---VVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGTT 1385
+A P +P T QT P LP P L + S+PA F + +S T+
Sbjct: 528 PLPTIASPPPPLPTTTPPPQTPPLPPLP-PIPALPQQPPLPPSQPA----FSQVPASSTS 582
Query: 1386 AKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPP 1445
P ++SA + S+A V + + V A HL LPP P
Sbjct: 583 TLPPSTHSKTSA-------VSSQANSQPPVQVSVKTQVSVTAAIP----HLKTSTLPPLP 631
Query: 1446 PPPPPPPPPPPVIPHPAAPS 1465
PP P P PS
Sbjct: 632 LPPLLPGDDDMDSPKETLPS 651
Score = 48.9 bits (115), Expect = 6e-05
Identities = 38/142 (26%), Positives = 61/142 (42%), Gaps = 22/142 (15%)
Query: 1347 KIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGT--TAKPLPVVKESSADLLLPPD 1404
K P+ P+ ++ S PA + L++ S T +P ++E+++D P
Sbjct: 1180 KEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQ 1239
Query: 1405 IISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAP 1464
+ P+E+ A P LP + PP PP PPPPPPPPP++
Sbjct: 1240 GPRRT--------PTMPQEE---AAACPPHILPPEKRPPEPPGPPPPPPPPPLV------ 1282
Query: 1465 SAAQANAILAPVKSNPVVSQTL 1486
+ + AP + NP V+ L
Sbjct: 1283 ---EGDLSSAPQELNPAVTAAL 1301
Score = 47.0 bits (110), Expect = 2e-04
Identities = 66/303 (21%), Positives = 110/303 (36%), Gaps = 56/303 (18%)
Query: 1281 PEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHTSPWMPVV 1340
P ++ KS +P+ S+ S K + ++ P+++ L+ +
Sbjct: 348 PSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERA 407
Query: 1341 TTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGTTAKPLP---------- 1390
+ K+ ++S + + P N+ + K SG +K LP
Sbjct: 408 AAAAAAKMDG---------KESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAP 458
Query: 1391 ------------VVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVL----------- 1427
VK SS + D S+ +++ +G+ + K +
Sbjct: 459 DTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKET 518
Query: 1428 --AEKSEPSHLPEQILPPPPPP----PPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPV 1481
+EK P LP PPPP P PP PP PP+ P PA P L P S P
Sbjct: 519 ETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPP----LPP--SQPA 572
Query: 1482 VSQ--TLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPP 1539
SQ S + P+ + V+ A++QP S +T V+ + ++ P
Sbjct: 573 FSQVPASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPL 632
Query: 1540 PPL 1542
PPL
Sbjct: 633 PPL 635
Score = 37.7 bits (86), Expect = 0.13
Identities = 59/190 (31%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query: 4 SSARSSVSSHRP------KDDGGGGPRSG--------RSSGSSSGPARRSSPPPPPSGSS 49
S R S S HR +DD G G RS SS+ + + SP GS+
Sbjct: 215 SPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSP-----GST 269
Query: 50 SRTPARRP--RSPSGHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRL-FPPGPAG- 105
SR + P + PS ++ SPSP R+ S SP RR S G P P G
Sbjct: 270 SRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGR 329
Query: 106 FRGSSRGESRADYARDGRGDHPGDSGSRRRSPGLC--SDSLEKSLRITVGNDHFCVSTPE 163
R SS S+ +R SR RSP S S K R + + H +S P
Sbjct: 330 RRSSSPFLSKRSLSRSPLPSRK-SMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSIS-PV 387
Query: 164 RRRLSDRLGS 173
R L+ LG+
Sbjct: 388 RLPLNSSLGA 397
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 57.0 bits (136), Expect = 2e-07
Identities = 65/263 (24%), Positives = 90/263 (34%), Gaps = 67/263 (25%)
Query: 1264 KKESPTSSSFGK---FSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPI 1320
K E P + + S K P K+ +K T + E+LE+ +DK++ + E K+
Sbjct: 2280 KPEGPVADTVSTDLLISEKDPVKKAKKE---TGNGIILEVLEAYRDKKELEAERTKSS-- 2334
Query: 1321 KIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIK 1380
+TV H + + Q + +T + KPA S
Sbjct: 2335 ----LSETVFDHPPSSVIALPMKEQ--------LSTTYFTSGETFGQEKPASQLPSGSPS 2382
Query: 1381 SSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQI 1440
S AKP P + SS D+ P
Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQP------------------------------------- 2405
Query: 1441 LPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVS--QTLSPGFVGPNILNP 1498
PPPPPPPPPPPPPPP P P P + P K V S T +P F L
Sbjct: 2406 -PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464
Query: 1499 V-------LPVAIMASAQPAAIP 1514
LPV + + P +P
Sbjct: 2465 TAVLRSNGLPVTRICTTAPPPVP 2487
Score = 39.3 bits (90), Expect = 0.045
Identities = 93/491 (18%), Positives = 186/491 (37%), Gaps = 82/491 (16%)
Query: 836 RVIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEER 895
++ P VT D+ KQ+ES A+ + + +P + PE +EK R+ +K+ ++EE+
Sbjct: 1184 KIPPMVTTDQ-KQEESKLEKDKASALQEKKPLPEEKKLIPE---EEKIRSEEKKPLLEEK 1239
Query: 896 EKLKNDRE-ARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMK 954
+ D++ + K + L K Q ++ +K +G P V+ + M+
Sbjct: 1240 KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEK---LEGRVAPKTVQEGKQPQTKME 1296
Query: 955 DIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREP--TEKPGKAEKSK-SP 1011
+ ++ E DK+ K++ + +P T KP + E K
Sbjct: 1297 GLPSGTPQSLPKED-----------------DKTTKTIKEQPQPPCTAKPDQVEPGKEKT 1339
Query: 1012 EKVSSFSNSSSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDC 1071
EK S++SS+++ K + + + + ++ S+ ++ E KD
Sbjct: 1340 EKEDDKSDTSSSQQPK--SPQGLSDTGYSSDGISSSLGEIPSLIPTDE---------KD- 1387
Query: 1072 NTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLV 1131
+ G D F+ + L S +++A A ++++K T P + S
Sbjct: 1388 -ILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVS---- 1442
Query: 1132 PISGFYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLE 1191
P + K +E + + E + E +
Sbjct: 1443 ----------------PEQPKDQEKTQSLSETLEITISEEEIKESQ-------------- 1472
Query: 1192 TERRRQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKR 1251
E R+ + K + P + ++K++ V ++ + + +E+ SE NSP + KR
Sbjct: 1473 -EERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEES-SESENSP-VPQRKR 1529
Query: 1252 NTGIKLQLKEEVKKESPTSS----SFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDK 1307
T + +E K+E S F + + +E+ S + ++ E S
Sbjct: 1530 RTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSST 1589
Query: 1308 EDGKTEAGKAK 1318
E K E K K
Sbjct: 1590 ESQKKEETKGK 1600
Score = 37.7 bits (86), Expect = 0.13
Identities = 114/490 (23%), Positives = 172/490 (35%), Gaps = 93/490 (18%)
Query: 1285 EEKSSLVTPSISKEEILESSKDKEDGKTEAGKA-KPIKIKLSGKTVVAHTSPWMPVVTTS 1343
++ S PS S++ K A ++ KP+ SGK P P T S
Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK-------PLQPP-TVS 573
Query: 1344 TQTKIRPNLPIPSTVLRKSCSAT-----MSKPAPLNTFLSIKSSGTTA---KPLPVVKES 1395
K P+ +P T+ C+ T + + A NT +++ + P P + E
Sbjct: 574 PSAKQPPSQGLPKTIC-PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
Query: 1396 SADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEK------SEPSHLPEQILPPPPPPP- 1448
L L + +A GG+ + SP+ K+ A S+ S P+Q P P
Sbjct: 633 KEWLCLNCQM-KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPK 691
Query: 1449 ------PPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPV 1502
P P PPP++ P + A A P + +S+ P PV
Sbjct: 692 QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS--LSKPAPPKEPSVPSEQDKAPV 749
Query: 1503 AIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLAT 1562
A QP + T VS S S +P P S V Q++ EK L T
Sbjct: 750 ADDKPKQPKMV--KPTTDLVSSS-------SATTKPDIPSSKV---QSQAEEKTTPPLKT 797
Query: 1563 ANAKDLYDIFYSSGGKGAP-ETKGAP----ETKLSG--------------GPLANGENSN 1603
+AK F +G K +P ++K P ++K+ P+ E
Sbjct: 798 DSAKPSQS-FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
Query: 1604 LSRTKSSDTSSTSPLNSSASQEELHQDEGLVAAPIVSNSEKPIAKT-LVALGKWSVVEHV 1662
++TK S P+ + + P S KP ++ +L S+ +
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD-- 914
Query: 1663 GPKSTGSTYGFLQPLTRLCQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSELDLG 1722
PKS QP T P ET+T K +S S S IS G
Sbjct: 915 APKS--------QPTT------PQETVTGK----LFGFGASIFSQASNLIS------TAG 950
Query: 1723 EPGPPGVEPP 1732
+PGP P
Sbjct: 951 QPGPHSQSGP 960
Score = 37.0 bits (84), Expect = 0.22
Identities = 33/133 (24%), Positives = 48/133 (36%), Gaps = 12/133 (9%)
Query: 1428 AEKSEPSHLPEQI---LPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQ 1484
A+++ P+ P Q+ PPP P P PPP PS + P + P
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520
Query: 1485 TLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSESDR--DQTLFSVLVRPPPPL 1542
PG P P SA+P+A P +S + QT ++PP
Sbjct: 521 PQQPGSTKPPSQQP-------GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 1543 SSVFSEQAKKLEK 1555
S ++ L K
Sbjct: 574 PSAKQPPSQGLPK 586
Score = 36.2 bits (82), Expect = 0.38
Identities = 84/381 (22%), Positives = 138/381 (36%), Gaps = 51/381 (13%)
Query: 1183 QAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRN 1242
+A L+ + E ERR+ + + + PK A++ ++ + S Q +
Sbjct: 42 EADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPD 101
Query: 1243 SPEKAE---NKRNTGIKLQLKEEVKKESPTSSSFGKFSWKKPEKEEEKSSL--------- 1290
A+ +K T + ++++ SP++ S + + KEE KSS+
Sbjct: 102 PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVN 161
Query: 1291 ----VTPSISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQT 1346
V+ ++K + D E + E K + + K GK P
Sbjct: 162 ALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPK 221
Query: 1347 KIRPNL-PIPSTVLRKSCSATMS---KPAPLNTFLSIKSSGTTAK----PLPVVKESSAD 1398
+ P P+ KS S+ K P T I+ T + LP+ +++S
Sbjct: 222 QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
Query: 1399 LLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPPPPPVI 1458
DI+ GE V K L S+P P Q P P PP P
Sbjct: 282 QTKQADIVR----GESV--------KPSLPSPSKP---PIQ-QPTPGKPPAQQPGHEKSQ 325
Query: 1459 PHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDET 1518
P PA P AQ + + P+ P T+ P P P P + A+P P+ +T
Sbjct: 326 PGPAKP-PAQPSGLTKPLAQQP---GTVKPPVQPPGTTKP--PAQPLGPAKP---PAQQT 376
Query: 1519 APGVSESDRDQTLFSVLVRPP 1539
G + +Q L +PP
Sbjct: 377 --GSEKPSSEQPGPKALAQPP 395
Score = 34.3 bits (77), Expect = 1.4
Identities = 28/108 (25%), Positives = 43/108 (39%), Gaps = 16/108 (14%)
Query: 15 PKDDGGGGPRSGRSSGSSSGPARRSSP--PPPPSGSSSRTPARRPRSPSGHRGRRASPSP 72
P G G S + +G + P++ P PPP ++ P ++P S P
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP----------GSAKP 499
Query: 73 PRGRRVSPSPPRARRG--SPSPPRGRRLFPPG--PAGFRGSSRGESRA 116
P + S PP + G PSP + PP P + S++ S A
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547
Score = 32.3 bits (72), Expect = 5.5
Identities = 60/299 (20%), Positives = 95/299 (31%), Gaps = 37/299 (12%)
Query: 1196 RQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGI 1255
++ + + + P + K K+ K VK + S +AE K +
Sbjct: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Query: 1256 KLQLKEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVT-PSISKEEILESSKDKEDGKTEA 1314
K + + PT F K + S +++ P S E + D K E
Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP 855
Query: 1315 GKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLN 1374
KA+ K+S P K P P P ++ P P
Sbjct: 856 KKAQT---KMS------------PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 1375 TF----LSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFG-GEEVILKGSPEEKVVLAE 1429
L++ S K P + + + K FG G + + S +++
Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQET--------VTGKLFGFGASIFSQASN----LIST 948
Query: 1430 KSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSP 1488
+P P P P P P P P P + A AP KS PV +T +P
Sbjct: 949 AGQPG--PHSQSGPGAPMKQAPAPSQP--PTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 57.0 bits (136), Expect = 2e-07
Identities = 65/263 (24%), Positives = 90/263 (34%), Gaps = 67/263 (25%)
Query: 1264 KKESPTSSSFGK---FSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPI 1320
K E P + + S K P K+ +K T + E+LE+ +DK++ + E K+
Sbjct: 2280 KPEGPVADTVSTDLLISEKDPVKKAKKE---TGNGIILEVLEAYRDKKELEAERTKSS-- 2334
Query: 1321 KIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIK 1380
+TV H + + Q + +T + KPA S
Sbjct: 2335 ----LSETVFDHPPSSVIALPMKEQ--------LSTTYFTSGETFGQEKPASQLPSGSPS 2382
Query: 1381 SSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQI 1440
S AKP P + SS D+ P
Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQP------------------------------------- 2405
Query: 1441 LPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVS--QTLSPGFVGPNILNP 1498
PPPPPPPPPPPPPPP P P P + P K V S T +P F L
Sbjct: 2406 -PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464
Query: 1499 V-------LPVAIMASAQPAAIP 1514
LPV + + P +P
Sbjct: 2465 TAVLRSNGLPVTRICTTAPPPVP 2487
Score = 39.3 bits (90), Expect = 0.045
Identities = 93/491 (18%), Positives = 186/491 (37%), Gaps = 82/491 (16%)
Query: 836 RVIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEER 895
++ P VT D+ KQ+ES A+ + + +P + PE +EK R+ +K+ ++EE+
Sbjct: 1184 KIPPMVTTDQ-KQEESKLEKDKASALQEKKPLPEEKKLIPE---EEKIRSEEKKPLLEEK 1239
Query: 896 EKLKNDRE-ARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMK 954
+ D++ + K + L K Q ++ +K +G P V+ + M+
Sbjct: 1240 KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEK---LEGRVAPKTVQEGKQPQTKME 1296
Query: 955 DIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREP--TEKPGKAEKSK-SP 1011
+ ++ E DK+ K++ + +P T KP + E K
Sbjct: 1297 GLPSGTPQSLPKED-----------------DKTTKTIKEQPQPPCTAKPDQVEPGKEKT 1339
Query: 1012 EKVSSFSNSSSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDC 1071
EK S++SS+++ K + + + + ++ S+ ++ E KD
Sbjct: 1340 EKEDDKSDTSSSQQPK--SPQGLSDTGYSSDGISSSLGEIPSLIPTDE---------KD- 1387
Query: 1072 NTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLV 1131
+ G D F+ + L S +++A A ++++K T P + S
Sbjct: 1388 -ILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVS---- 1442
Query: 1132 PISGFYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLE 1191
P + K +E + + E + E +
Sbjct: 1443 ----------------PEQPKDQEKTQSLSETLEITISEEEIKESQ-------------- 1472
Query: 1192 TERRRQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKR 1251
E R+ + K + P + ++K++ V ++ + + +E+ SE NSP + KR
Sbjct: 1473 -EERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEES-SESENSP-VPQRKR 1529
Query: 1252 NTGIKLQLKEEVKKESPTSS----SFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDK 1307
T + +E K+E S F + + +E+ S + ++ E S
Sbjct: 1530 RTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSST 1589
Query: 1308 EDGKTEAGKAK 1318
E K E K K
Sbjct: 1590 ESQKKEETKGK 1600
Score = 37.7 bits (86), Expect = 0.13
Identities = 114/490 (23%), Positives = 172/490 (35%), Gaps = 93/490 (18%)
Query: 1285 EEKSSLVTPSISKEEILESSKDKEDGKTEAGKA-KPIKIKLSGKTVVAHTSPWMPVVTTS 1343
++ S PS S++ K A ++ KP+ SGK P P T S
Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK-------PLQPP-TVS 573
Query: 1344 TQTKIRPNLPIPSTVLRKSCSAT-----MSKPAPLNTFLSIKSSGTTA---KPLPVVKES 1395
K P+ +P T+ C+ T + + A NT +++ + P P + E
Sbjct: 574 PSAKQPPSQGLPKTIC-PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
Query: 1396 SADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEK------SEPSHLPEQILPPPPPPP- 1448
L L + +A GG+ + SP+ K+ A S+ S P+Q P P
Sbjct: 633 KEWLCLNCQM-KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPK 691
Query: 1449 ------PPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPV 1502
P P PPP++ P + A A P + +S+ P PV
Sbjct: 692 QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS--LSKPAPPKEPSVPSEQDKAPV 749
Query: 1503 AIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLAT 1562
A QP + T VS S S +P P S V Q++ EK L T
Sbjct: 750 ADDKPKQPKMV--KPTTDLVSSS-------SATTKPDIPSSKV---QSQAEEKTTPPLKT 797
Query: 1563 ANAKDLYDIFYSSGGKGAP-ETKGAP----ETKLSG--------------GPLANGENSN 1603
+AK F +G K +P ++K P ++K+ P+ E
Sbjct: 798 DSAKPSQS-FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
Query: 1604 LSRTKSSDTSSTSPLNSSASQEELHQDEGLVAAPIVSNSEKPIAKT-LVALGKWSVVEHV 1662
++TK S P+ + + P S KP ++ +L S+ +
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD-- 914
Query: 1663 GPKSTGSTYGFLQPLTRLCQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSELDLG 1722
PKS QP T P ET+T K +S S S IS G
Sbjct: 915 APKS--------QPTT------PQETVTGK----LFGFGASIFSQASNLIS------TAG 950
Query: 1723 EPGPPGVEPP 1732
+PGP P
Sbjct: 951 QPGPHSQSGP 960
Score = 37.0 bits (84), Expect = 0.22
Identities = 33/133 (24%), Positives = 48/133 (36%), Gaps = 12/133 (9%)
Query: 1428 AEKSEPSHLPEQI---LPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQ 1484
A+++ P+ P Q+ PPP P P PPP PS + P + P
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520
Query: 1485 TLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSESDR--DQTLFSVLVRPPPPL 1542
PG P P SA+P+A P +S + QT ++PP
Sbjct: 521 PQQPGSTKPPSQQP-------GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 1543 SSVFSEQAKKLEK 1555
S ++ L K
Sbjct: 574 PSAKQPPSQGLPK 586
Score = 36.2 bits (82), Expect = 0.38
Identities = 84/381 (22%), Positives = 138/381 (36%), Gaps = 51/381 (13%)
Query: 1183 QAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRN 1242
+A L+ + E ERR+ + + + PK A++ ++ + S Q +
Sbjct: 42 EADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPD 101
Query: 1243 SPEKAE---NKRNTGIKLQLKEEVKKESPTSSSFGKFSWKKPEKEEEKSSL--------- 1290
A+ +K T + ++++ SP++ S + + KEE KSS+
Sbjct: 102 PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVN 161
Query: 1291 ----VTPSISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQT 1346
V+ ++K + D E + E K + + K GK P
Sbjct: 162 ALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPK 221
Query: 1347 KIRPNL-PIPSTVLRKSCSATMS---KPAPLNTFLSIKSSGTTAK----PLPVVKESSAD 1398
+ P P+ KS S+ K P T I+ T + LP+ +++S
Sbjct: 222 QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
Query: 1399 LLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPPPPPVI 1458
DI+ GE V K L S+P P Q P P PP P
Sbjct: 282 QTKQADIVR----GESV--------KPSLPSPSKP---PIQ-QPTPGKPPAQQPGHEKSQ 325
Query: 1459 PHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDET 1518
P PA P AQ + + P+ P T+ P P P P + A+P P+ +T
Sbjct: 326 PGPAKP-PAQPSGLTKPLAQQP---GTVKPPVQPPGTTKP--PAQPLGPAKP---PAQQT 376
Query: 1519 APGVSESDRDQTLFSVLVRPP 1539
G + +Q L +PP
Sbjct: 377 --GSEKPSSEQPGPKALAQPP 395
Score = 34.3 bits (77), Expect = 1.4
Identities = 28/108 (25%), Positives = 43/108 (39%), Gaps = 16/108 (14%)
Query: 15 PKDDGGGGPRSGRSSGSSSGPARRSSP--PPPPSGSSSRTPARRPRSPSGHRGRRASPSP 72
P G G S + +G + P++ P PPP ++ P ++P S P
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP----------GSAKP 499
Query: 73 PRGRRVSPSPPRARRG--SPSPPRGRRLFPPG--PAGFRGSSRGESRA 116
P + S PP + G PSP + PP P + S++ S A
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547
Score = 32.3 bits (72), Expect = 5.5
Identities = 60/299 (20%), Positives = 95/299 (31%), Gaps = 37/299 (12%)
Query: 1196 RQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGI 1255
++ + + + P + K K+ K VK + S +AE K +
Sbjct: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Query: 1256 KLQLKEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVT-PSISKEEILESSKDKEDGKTEA 1314
K + + PT F K + S +++ P S E + D K E
Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP 855
Query: 1315 GKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLN 1374
KA+ K+S P K P P P ++ P P
Sbjct: 856 KKAQT---KMS------------PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 1375 TF----LSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFG-GEEVILKGSPEEKVVLAE 1429
L++ S K P + + + K FG G + + S +++
Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQET--------VTGKLFGFGASIFSQASN----LIST 948
Query: 1430 KSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSP 1488
+P P P P P P P P P + A AP KS PV +T +P
Sbjct: 949 AGQPG--PHSQSGPGAPMKQAPAPSQP--PTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 56.6 bits (135), Expect = 3e-07
Identities = 35/126 (27%), Positives = 50/126 (39%), Gaps = 18/126 (14%)
Query: 1389 LPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPP----- 1443
+ + K+ D+ + P + S ++ G+ + A S P P LPP
Sbjct: 481 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP 540
Query: 1444 -------------PPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGF 1490
PPPPPPPPPPPPP P P A + AP + P+ S PG
Sbjct: 541 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGT 600
Query: 1491 VGPNIL 1496
P ++
Sbjct: 601 SSPTVV 606
Score = 36.2 bits (82), Expect = 0.38
Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 22 GPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPS 81
GP G +SSGP PP PPS + T P +P P PP P
Sbjct: 515 GPTMG---AASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPP 571
Query: 82 PP---RARRGSPSPPRGRRLFPPGPA 104
PP A P+PP L PP P+
Sbjct: 572 PPLPGPAAETVPAPP----LAPPLPS 593
Score = 33.9 bits (76), Expect = 1.9
Identities = 29/82 (35%), Positives = 31/82 (37%), Gaps = 15/82 (18%)
Query: 25 SGRSSGSSSGPARRSS--PPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPSP 82
+G S G + G A PPPPP SS TP P P PP P P
Sbjct: 510 AGNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPV------TPPMPP-----PPPP 558
Query: 83 PRARRGSPSPPRGRRLFPPGPA 104
P P PP L PGPA
Sbjct: 559 PPPPPPPPPPPPPPPL--PGPA 578
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 56.6 bits (135), Expect = 3e-07
Identities = 52/206 (25%), Positives = 87/206 (42%), Gaps = 16/206 (7%)
Query: 1400 LLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHL---PEQILPPPPPP---PPPPPP 1453
++PP + + + + S + + +K + SH P+Q LPPPPPP PPPP P
Sbjct: 413 IVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLP 472
Query: 1454 PPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAI 1513
PPP PHP P + + P SQ + + + ++ AQ ++
Sbjct: 473 PPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSL 532
Query: 1514 PSDETAPGVSESDRDQTL---FSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYD 1570
+T S QT+ + +VR P P+ S Q + L+ + A+ +K
Sbjct: 533 QLSQTK---SPQHLQQTIVGQINYIVRQPAPVQS--QSQEETLQATDEPPASQGSKPALP 587
Query: 1571 IFYSSGGKGAPETKGAPETKLSGGPL 1596
+ ++ P+ G ET LS P+
Sbjct: 588 LDKNTAA-ALPQASG-EETPLSVPPV 611
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 56.6 bits (135), Expect = 3e-07
Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 10/103 (9%)
Query: 32 SSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPSPP-----RAR 86
S+ A R+ PPPP ++ +P++R R+PS PR R +P PP
Sbjct: 678 SAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATA 737
Query: 87 RGSPSPPRGRRLFPPGPAGFRG-----SSRGESRADYARDGRG 124
+PSPPR R P P G G + R E+ + A D RG
Sbjct: 738 LAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRG 780
Score = 36.2 bits (82), Expect = 0.38
Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 7/110 (6%)
Query: 3 RSSARSSVSSHRPKDDGGGGPRS-GRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPS 61
RS A+ + ++ D G RS GR+ + R P PP S PA R+P
Sbjct: 762 RSPAKRAEAASMLAADVRGKTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPP 821
Query: 62 GHRGRRASPSPPRGRRVSPSPPRARRGSP--SPPRGRRLFPPGPAGFRGS 109
+P P + P+P R+ +P PPR + G G G+
Sbjct: 822 A----TETPGPEKAATDLPAPETPRKKTPIQKPPRKKSREAAGELGRAGA 867
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105,340,276
Number of Sequences: 37866
Number of extensions: 6303286
Number of successful extensions: 102434
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 931
Number of HSP's successfully gapped in prelim test: 2251
Number of HSP's that attempted gapping in prelim test: 42119
Number of HSP's gapped (non-prelim): 37679
length of query: 2279
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2161
effective length of database: 13,779,330
effective search space: 29777132130
effective search space used: 29777132130
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.