KL 23949

Name: KL	Sequence: fasta or formatted (1012aa)		NCBI GI: 24497614
Description: klotho		Referenced in: Bone and Related Tissues Galactose and Lactose
Composition: Amino acid Percentage Count Longest homopolymer A alanine 7.5 76 2 C cysteine 1.2 12 1 D aspartate 5.4 55 2 E glutamate 4.6 47 2 F phenylalanine 6.0 61 2 G glycine 6.6 67 2 H histidine 3.2 32 2 I isoleucine 4.7 48 2 K lysine 4.6 47 2 L leucine 11.0 111 3 M methionine 1.8 18 1 N asparagine 4.1 41 2 P proline 6.3 64 4 Q glutamine 4.2 42 2 R arginine 5.7 58 2 S serine 5.8 59 2 T threonine 4.3 44 2 V valine 5.0 51 2 W tryptophan 3.0 30 1 Y tyrosine 4.8 49 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 klotho KLB 0.418 klotho beta LCT 0.300 lactase-phlorizin hydrolase preproprotein LCTL 0.167 lactase-like GBA3 0.160 cytosolic beta-glucosidase isoform a GBA3 0.037 cytosolic beta-glucosidase isoform b LOC100293776 0.006 PREDICTED: hypothetical protein LOC100288658 0.006 PREDICTED: hypothetical protein XP_002342750 LOC100288658 0.006 PREDICTED: hypothetical protein C4orf48 0.005 hypothetical protein LOC401115 GRID2IP 0.005 glutamate receptor, ionotropic, delta 2 (Grid2) int... NRXN2 0.005 neurexin 2 isoform alpha-1 precursor NRXN2 0.005 neurexin 2 isoform alpha-2 precursor KIAA1522 0.005 hypothetical protein LOC57648 SCAMP1 0.004 secretory carrier membrane protein 1 BAT2D1 0.004 HBxAg transactivated protein 2 SMCR7 0.003 Smith-Magenis syndrome chromosome region, candidate... FUCA1 0.003 fucosidase, alpha-L-1, tissue GABBR2 0.003 G protein-coupled receptor 51 PLXNC1 0.003 plexin C1 HS3ST4 0.003 heparan sulfate D-glucosaminyl 3-O-sulfotransferase... ADAMTS5 0.003 ADAM metallopeptidase with thrombospondin type 1 mo... IGFBP2 0.002 insulin-like growth factor binding protein 2, 36kDa ... NKX2-5 0.002 NK2 transcription factor related, locus 5 SORCS2 0.002 VPS10 domain receptor protein SORCS 2 VGF 0.002 VGF nerve growth factor inducible precursor Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.