Guide to the Human Genome
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Name: KL Sequence: fasta or formatted (1012aa) NCBI GI: 24497614
Description:

klotho

Referenced in:

Bone and Related Tissues
Galactose and Lactose

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.5         76           2
 C cysteine            1.2         12           1
 D aspartate           5.4         55           2
 E glutamate           4.6         47           2
 F phenylalanine       6.0         61           2
 G glycine             6.6         67           2
 H histidine           3.2         32           2
 I isoleucine          4.7         48           2
 K lysine              4.6         47           2
 L leucine            11.0        111           3
 M methionine          1.8         18           1
 N asparagine          4.1         41           2
 P proline             6.3         64           4
 Q glutamine           4.2         42           2
 R arginine            5.7         58           2
 S serine              5.8         59           2
 T threonine           4.3         44           2
 V valine              5.0         51           2
 W tryptophan          3.0         30           1
 Y tyrosine            4.8         49           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   klotho 
KLB                   0.418   klotho beta 
LCT                   0.300   lactase-phlorizin hydrolase preproprotein 
LCTL                  0.167   lactase-like 
GBA3                  0.160   cytosolic beta-glucosidase isoform a 
GBA3                  0.037   cytosolic beta-glucosidase isoform b 
LOC100293776          0.006   PREDICTED: hypothetical protein 
LOC100288658          0.006   PREDICTED: hypothetical protein XP_002342750 
LOC100288658          0.006   PREDICTED: hypothetical protein 
C4orf48               0.005   hypothetical protein LOC401115 
GRID2IP               0.005   glutamate receptor, ionotropic, delta 2 (Grid2) int...
NRXN2                 0.005   neurexin 2 isoform alpha-1 precursor 
NRXN2                 0.005   neurexin 2 isoform alpha-2 precursor 
KIAA1522              0.005   hypothetical protein LOC57648 
SCAMP1                0.004   secretory carrier membrane protein 1 
BAT2D1                0.004   HBxAg transactivated protein 2 
SMCR7                 0.003   Smith-Magenis syndrome chromosome region, candidate...
FUCA1                 0.003   fucosidase, alpha-L-1, tissue 
GABBR2                0.003   G protein-coupled receptor 51 
PLXNC1                0.003   plexin C1 
HS3ST4                0.003   heparan sulfate D-glucosaminyl 3-O-sulfotransferase...
ADAMTS5               0.003   ADAM metallopeptidase with thrombospondin type 1 mo...
IGFBP2                0.002   insulin-like growth factor binding protein 2, 36kDa ...
NKX2-5                0.002   NK2 transcription factor related, locus 5 
SORCS2                0.002   VPS10 domain receptor protein SORCS 2 
VGF                   0.002   VGF nerve growth factor inducible precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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