Guide to the Human Genome
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Name: LCT Sequence: fasta or formatted (1927aa) NCBI GI: 32481206
Description:

lactase-phlorizin hydrolase preproprotein

Referenced in:

Stomach, Small Intestine, and Colon
Galactose and Lactose
Polymorphism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.7        149           2
 C cysteine            1.0         19           1
 D aspartate           6.0        116           2
 E glutamate           5.3        102           3
 F phenylalanine       5.8        111           2
 G glycine             6.5        126           2
 H histidine           3.1         59           2
 I isoleucine          4.7         90           2
 K lysine              3.9         76           2
 L leucine             8.8        170           3
 M methionine          1.3         26           1
 N asparagine          4.3         82           2
 P proline             5.5        106           2
 Q glutamine           4.2         80           3
 R arginine            5.4        105           2
 S serine              8.4        161           4
 T threonine           5.3        103           2
 V valine              5.5        106           2
 W tryptophan          2.8         53           1
 Y tyrosine            4.5         87           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   lactase-phlorizin hydrolase preproprotein 
KL                    0.158   klotho 
KLB                   0.155   klotho beta 
LCTL                  0.115   lactase-like 
GBA3                  0.108   cytosolic beta-glucosidase isoform a 
GBA3                  0.024   cytosolic beta-glucosidase isoform b 
HEPHL1                0.004   hephaestin-like 1 
DYNC1H1               0.002   cytoplasmic dynein 1 heavy chain 1 
ANKH                  0.002   progressive ankylosis protein 
BAHCC1                0.002   BAH domain and coiled-coil containing 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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