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Search of human proteins with 24496763
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24496763 mucolipin 3 [Homo sapiens]
(553 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24496763 mucolipin 3 [Homo sapiens] 1130 0.0
gi|54792073 mucolipin 2 [Homo sapiens] 654 0.0
gi|10092597 mucolipin 1 [Homo sapiens] 623 e-178
gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens] 59 1e-08
gi|4505835 polycystin 2 [Homo sapiens] 57 4e-08
gi|5174633 receptor for egg jelly-like protein precursor [Homo s... 54 4e-07
gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] 48 3e-05
gi|26051223 sperm-associated cation channel 2 isoform 2 [Homo sa... 37 0.036
gi|16876443 sperm-associated cation channel 2 isoform 1 [Homo sa... 37 0.036
gi|17505200 transient receptor potential cation channel, subfami... 37 0.047
gi|21314682 transient receptor potential cation channel, subfami... 33 0.68
gi|62988334 cation channel, sperm associated 4 [Homo sapiens] 32 1.2
gi|21735483 transient receptor potential cation channel, subfami... 32 1.5
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 32 1.5
gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I... 32 2.0
gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I... 32 2.0
gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens] 32 2.0
gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s... 31 2.6
gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s... 31 2.6
gi|169206328 PREDICTED: hypothetical protein [Homo sapiens] 31 3.4
gi|219689113 two pore segment channel 1 isoform 1 [Homo sapiens] 30 4.4
gi|29725622 two pore segment channel 1 isoform 2 [Homo sapiens] 30 4.4
gi|24119274 voltage gated channel like 1 [Homo sapiens] 30 4.4
gi|169210316 PREDICTED: hypothetical protein [Homo sapiens] 30 5.8
gi|188035871 SET and MYND domain containing 2 [Homo sapiens] 30 5.8
gi|20070163 voltage-dependent calcium channel alpha 1G subunit i... 30 7.5
gi|38505292 voltage-dependent calcium channel alpha 1G subunit i... 30 7.5
gi|38505290 voltage-dependent calcium channel alpha 1G subunit i... 30 7.5
gi|38505288 voltage-dependent calcium channel alpha 1G subunit i... 30 7.5
gi|38505286 voltage-dependent calcium channel alpha 1G subunit i... 30 7.5
>gi|24496763 mucolipin 3 [Homo sapiens]
Length = 553
Score = 1130 bits (2924), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 1 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP 60
MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
Sbjct: 1 MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP 60
Query: 61 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS 120
WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
Sbjct: 61 WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS 120
Query: 121 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE 180
DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
Sbjct: 121 DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE 180
Query: 181 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD 240
IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
Sbjct: 181 IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD 240
Query: 241 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL 300
FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
Sbjct: 241 FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL 300
Query: 301 ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM 360
ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
Sbjct: 301 ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM 360
Query: 361 EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA 420
EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA
Sbjct: 361 EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA 420
Query: 421 MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI 480
MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI
Sbjct: 421 MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI 480
Query: 481 YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE 540
YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE
Sbjct: 481 YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE 540
Query: 541 DDPPVSLFCCCKK 553
DDPPVSLFCCCKK
Sbjct: 541 DDPPVSLFCCCKK 553
>gi|54792073 mucolipin 2 [Homo sapiens]
Length = 566
Score = 654 bits (1686), Expect = 0.0
Identities = 310/521 (59%), Positives = 404/521 (77%), Gaps = 5/521 (0%)
Query: 35 EDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEEN 94
E+ +R LKF+FM+PCEK+ AR + PWKL +QILKI MVT QLV FGLSNQ+VVAFKE+N
Sbjct: 38 EECLREDLKFYFMSPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDN 97
Query: 95 TIAFKHLFLKGYMDRMDDTYA--VYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTK 152
T+AFKHLFLKGY +D Y+ VYTQ D Y+ + FA+NQY QL ++++G Y
Sbjct: 98 TVAFKHLFLKGYSGTDEDDYSCSVYTQEDAYESIFFAINQYHQLKDITLGTLGYGENEDN 157
Query: 153 QSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHR 212
+ + +C+ YK+G ++P N+T +ID ++E +C ++ + +N L+F+R
Sbjct: 158 RIGLKVCKQHYKKGTMFPSNETLNIDNDVELDCVQLDLQDLSKKPPDWKNSSFFRLEFYR 217
Query: 213 LLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDW 272
LL VE+ F LK I+LQT+ +ELPDCY F TI FDNKAHSG+IKI D+D I ECKD
Sbjct: 218 LLQVEISFHLKGIDLQTIHSRELPDCYVFQNTIIFDNKAHSGKIKIYFDSDAKIEECKDL 277
Query: 273 HVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVS 332
++ GS QKN Y+++FDAFVI+ CL SLILC RS++ L+L++ F+NFFL YK+ V +
Sbjct: 278 NIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRKRFLNFFLEKYKRPVCDT 337
Query: 333 DQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYL 392
DQ EF+NGWY+++IISD++TIIGSILKMEI+AK+LT+YD+CSI LGTST+LVW+GVIRYL
Sbjct: 338 DQWEFINGWYVLVIISDLMTIIGSILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYL 397
Query: 393 GFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLF 452
G+F YN+LILT+QA+LP V+RFC CA MIYLGY FCGWIVLGPYHDKF +LN V+ECLF
Sbjct: 398 GYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHDKFENLNTVAECLF 457
Query: 453 SLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQ 512
SL+NGDDMFATFA++QQKS LVWLFSR+YLYSFISLFIYMILSLFIALITD+Y+TIK++Q
Sbjct: 458 SLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQ 517
Query: 513 QDGFPETELRTFISECKDLPNSGKYRLEDDPPVSLFCCCKK 553
Q+GFPET+L+ F+ EC + +Y+ E +S CC ++
Sbjct: 518 QNGFPETDLQEFLKECS---SKEEYQKESSAFLSCICCRRR 555
>gi|10092597 mucolipin 1 [Homo sapiens]
Length = 580
Score = 623 bits (1606), Expect = e-178
Identities = 305/532 (57%), Positives = 395/532 (74%), Gaps = 17/532 (3%)
Query: 35 EDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEEN 94
E+ +RR+LK+FFM+PC+KF A+GRKP KL +Q++KI +VT+QL+LFGLSNQ+ V F+EEN
Sbjct: 38 EEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREEN 97
Query: 95 TIAFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKG---- 150
TIAF+HLFL GY D DDT+A YT+ +Y + AV+QYL L +VS+G +AY G
Sbjct: 98 TIAFRHLFLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPW 157
Query: 151 TKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDE--------PFHIGTPAEN 202
T S +A+CQ +Y RG++ P NDTFDIDP + T+C V+P E + + +
Sbjct: 158 TNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLESSSS 217
Query: 203 KLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDN 262
NLTL FH+L+ V + F+LK INLQ++ + E+PDCY F++ ITFDNKAHSGRI ISL+
Sbjct: 218 YKNLTLKFHKLVNVTIHFRLKTINLQSLINNEIPDCYTFSVLITFDNKAHSGRIPISLET 277
Query: 263 DISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFL 322
I+ECK H S + + ++FD VILTC +S +LC RS++RG LQ EFV F
Sbjct: 278 QAHIQECK--HPSVFQHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMW 335
Query: 323 LHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTM 382
+ +S+ +++EFVNGWYI+++ SD+LTI G+I+K+ I+AK+L SYDVCSILLGTST+
Sbjct: 336 RQRGRVISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTL 395
Query: 383 LVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFR 442
LVW+GVIRYL FF YN+LI TL+ ALP+V+RFCCC A+IYLGYCFCGWIVLGPYH KFR
Sbjct: 396 LVWVGVIRYLTFFHNYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFR 455
Query: 443 SLNMVSECLFSLINGDDMFATFAKMQQ---KSYLVWLFSRIYLYSFISLFIYMILSLFIA 499
SL+MVSECLFSLINGDDMF TFA MQ +S LVWLFS++YLYSFISLFIYM+LSLFIA
Sbjct: 456 SLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIA 515
Query: 500 LITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLEDDPPVSLFCCC 551
LIT Y+TIK G E+EL+ +I++C+D P SGK+R SL CCC
Sbjct: 516 LITGAYDTIKHPGGAGAEESELQAYIAQCQDSPTSGKFRRGSGSACSLLCCC 567
>gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]
Length = 613
Score = 58.9 bits (141), Expect = 1e-08
Identities = 32/134 (23%), Positives = 65/134 (48%), Gaps = 6/134 (4%)
Query: 376 LLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLG 435
++ + W+ + +++ F + L TL + +++ F +I+ Y G++V G
Sbjct: 371 IIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFG 430
Query: 436 PYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILS 495
D F + F ++ GD FA +QQ + ++ IY +FI +++L+
Sbjct: 431 SQVDDFSTFQNSIFAQFRIVLGD---FNFAGIQQANPIL---GPIYFITFIFFVFFVLLN 484
Query: 496 LFIALITDTYETIK 509
+F+A+I DTY +K
Sbjct: 485 MFLAIINDTYSEVK 498
>gi|4505835 polycystin 2 [Homo sapiens]
Length = 968
Score = 57.0 bits (136), Expect = 4e-08
Identities = 36/153 (23%), Positives = 68/153 (44%), Gaps = 12/153 (7%)
Query: 376 LLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLG 435
+ + VW+ + +++ F + L T+ ++ F +I+L Y ++V G
Sbjct: 561 IAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFG 620
Query: 436 PYHDKFRSLNMVSECLFS---LINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYM 492
D F + EC+F+ +I GD FA + + + IY +F+ ++
Sbjct: 621 TQVDDFSTF---QECIFTQFRIILGDINFAEIEEANR------VLGPIYFTTFVFFMFFI 671
Query: 493 ILSLFIALITDTYETIKQYQQDGFPETELRTFI 525
+L++F+A+I DTY +K E EL I
Sbjct: 672 LLNMFLAIINDTYSEVKSDLAQQKAEMELSDLI 704
>gi|5174633 receptor for egg jelly-like protein precursor [Homo
sapiens]
Length = 2253
Score = 53.9 bits (128), Expect = 4e-07
Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 12/162 (7%)
Query: 372 VCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGW 431
+ I+LG L L +RY FF L +QAALP + ++ + Y G+
Sbjct: 2049 IMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGY 2108
Query: 432 IVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIY 491
+V G + + +L ++ +FS F+ + + ++L SF+ + I
Sbjct: 2109 LVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSNNR-------ILGVLFLSSFMLVMIC 2161
Query: 492 MILSLFIALITDTYETIKQ--YQQDGFPETELRTFISECKDL 531
++++LF A+I YE +KQ Y++ P E+ C+ L
Sbjct: 2162 VLINLFQAVILSAYEEMKQPVYEE---PSDEVEAMTYLCRKL 2200
>gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]
Length = 805
Score = 47.8 bits (112), Expect = 3e-05
Identities = 24/126 (19%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 385 WLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSL 444
W+ + +Y+ F L TL +++ F +++ Y G+++ G + F +
Sbjct: 450 WIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTF 509
Query: 445 NMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDT 504
F +I GD + + + Y +++ +++L++F+A+I DT
Sbjct: 510 IKCIFTQFRIILGDFDYNAIDNANR------ILGPAYFVTYVFFVFFVLLNMFLAIINDT 563
Query: 505 YETIKQ 510
Y +K+
Sbjct: 564 YSEVKE 569
>gi|26051223 sperm-associated cation channel 2 isoform 2 [Homo
sapiens]
Length = 530
Score = 37.4 bits (85), Expect = 0.036
Identities = 51/271 (18%), Positives = 103/271 (38%), Gaps = 32/271 (11%)
Query: 272 WHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFF-LLHYKKEVS 330
W + + KN ++F +IL + L+ + + L+L E +F LL + E+
Sbjct: 103 WVLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEIL 162
Query: 331 VSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIR 390
+ F W + D + + S+L + +L+G + VWL ++R
Sbjct: 163 LKWLSNFSVFWKSAWNVFDFVVTMLSLLPEVV------------VLVGVTGQSVWLQLLR 210
Query: 391 Y---------LGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPY---- 437
L F + ++IL L AL ++ + + + G V Y
Sbjct: 211 ICRVLRSLKLLAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVFSEYTRSP 270
Query: 438 ------HDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIY 491
H F L +F L D +A + + + +FS IY ++ L
Sbjct: 271 RQDLEYHVFFSDLPNSLVTVFILFTLDHWYALLQDVWKVPEVSRIFSSIYFILWLLLGSI 330
Query: 492 MILSLFIALITDTYETIKQYQQDGFPETELR 522
+ S+ +A++ ++ I++ + E++
Sbjct: 331 IFRSIIVAMMVTNFQNIRKELNEEMARREVQ 361
>gi|16876443 sperm-associated cation channel 2 isoform 1 [Homo
sapiens]
Length = 528
Score = 37.4 bits (85), Expect = 0.036
Identities = 51/271 (18%), Positives = 103/271 (38%), Gaps = 32/271 (11%)
Query: 272 WHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFF-LLHYKKEVS 330
W + + KN ++F +IL + L+ + + L+L E +F LL + E+
Sbjct: 103 WVLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEIL 162
Query: 331 VSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIR 390
+ F W + D + + S+L + +L+G + VWL ++R
Sbjct: 163 LKWLSNFSVFWKSAWNVFDFVVTMLSLLPEVV------------VLVGVTGQSVWLQLLR 210
Query: 391 Y---------LGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPY---- 437
L F + ++IL L AL ++ + + + G V Y
Sbjct: 211 ICRVLRSLKLLAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVFSEYTRSP 270
Query: 438 ------HDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIY 491
H F L +F L D +A + + + +FS IY ++ L
Sbjct: 271 RQDLEYHVFFSDLPNSLVTVFILFTLDHWYALLQDVWKVPEVSRIFSSIYFILWLLLGSI 330
Query: 492 MILSLFIALITDTYETIKQYQQDGFPETELR 522
+ S+ +A++ ++ I++ + E++
Sbjct: 331 IFRSIIVAMMVTNFQNIRKELNEEMARREVQ 361
>gi|17505200 transient receptor potential cation channel, subfamily
V, member 5 [Homo sapiens]
Length = 729
Score = 37.0 bits (84), Expect = 0.047
Identities = 40/192 (20%), Positives = 87/192 (45%), Gaps = 20/192 (10%)
Query: 350 ILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAAL 409
I+T +L + + T+ +V + + + +L W V+ + F + +Q +
Sbjct: 429 IITYASLVLVTMVMRLTNTNGEV--VPMSFALVLGWCSVMYFTRGFQMLGPFTIMIQKMI 486
Query: 410 -PNVIRFCCCAAMIYLGYCFCGWIV--------LGPYHDKFRSLNMVSECLFSLINGDDM 460
+++RFC A++ LG+ +I+ LG ++D +L E ++I+
Sbjct: 487 FGDLMRFCWLMAVVILGFASAFYIIFQTEDPTSLGQFYDYPMALFTTFELFLTVID---- 542
Query: 461 FATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETE 520
A L ++FS I ++F + ++L+LFIA++ DT+ + Q + + +
Sbjct: 543 ----APANYDVDLPFMFS-IVNFAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQV 597
Query: 521 LRTFISECKDLP 532
+ T + + LP
Sbjct: 598 VATTVMLERKLP 609
>gi|21314682 transient receptor potential cation channel, subfamily
V, member 6 [Homo sapiens]
Length = 725
Score = 33.1 bits (74), Expect = 0.68
Identities = 34/173 (19%), Positives = 80/173 (46%), Gaps = 23/173 (13%)
Query: 341 WYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNL 400
++++II + ++ ++++ I A +++LG ++ + + LG F
Sbjct: 425 FHVLIITYAFMVLVTMVMRL-ISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFT---- 479
Query: 401 LILTLQAALPNVIRFCCCAAMIYLGYCFCGWIV--------LGPYHDKFRSLNMVSECLF 452
I+ + +++RFC A++ LG+ +I+ LG ++D +L E
Sbjct: 480 -IMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFL 538
Query: 453 SLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTY 505
++I+G + L +++S Y +F + ++L+L IA++ DT+
Sbjct: 539 TIIDGPANY--------NVDLPFMYSITYA-AFAIIATLLMLNLLIAMMGDTH 582
>gi|62988334 cation channel, sperm associated 4 [Homo sapiens]
Length = 472
Score = 32.3 bits (72), Expect = 1.2
Identities = 23/119 (19%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 401 LILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDK-FRSLNMVSECLFSLINGD- 458
+I + ++P++ L + G + G + K F+++ + LF I D
Sbjct: 203 IIRVILQSVPDMANIMVLILFFMLVFSVFGVTLFGAFVPKHFQNIQVALYTLFICITQDG 262
Query: 459 --DMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDG 515
D+++ F + +++ Y + + IY FI++ ++ ++LF+ ++T E + + + G
Sbjct: 263 WVDIYSDF-QTEKREYAMEIGGAIYFTIFITIGAFIGINLFVIVVTTNLEQMMKAGEQG 320
>gi|21735483 transient receptor potential cation channel, subfamily
V, member 3 [Homo sapiens]
Length = 790
Score = 32.0 bits (71), Expect = 1.5
Identities = 38/198 (19%), Positives = 81/198 (40%), Gaps = 12/198 (6%)
Query: 339 NGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKY 398
+ W+ + + +I S+ K + V ++ LG + ML + + +G ++
Sbjct: 519 DAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYS-- 576
Query: 399 NLLILTLQAALPNVIRFCCCAAMIYLGY--CFCGWIVLGPYHDK-FRSLNMVSECLFSLI 455
++ + L +V++F + LG+ I P +K S S+ + L
Sbjct: 577 ---VMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSFSDAVLELF 633
Query: 456 NGDDMFATFAKMQQKSY-LVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQD 514
Q Y +++LF L +++ L ++L++ IAL+ +T E + + +
Sbjct: 634 KLTIGLGDLNIQQNSKYPILFLF---LLITYVILTFVLLLNMLIALMGETVENVSKESER 690
Query: 515 GFPETELRTFISECKDLP 532
+ RT + K LP
Sbjct: 691 IWRLQRARTILEFEKMLP 708
>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
subunit [Homo sapiens]
Length = 2339
Score = 32.0 bits (71), Expect = 1.5
Identities = 49/257 (19%), Positives = 98/257 (38%), Gaps = 39/257 (15%)
Query: 271 DWHVSGSIQKNTHYMMI--FDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKE 328
++ + I NT +M+ +DA ++ + + + + ++ + + F +L+Y
Sbjct: 1474 EYFIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNY--- 1530
Query: 329 VSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGV 388
F + W + D +T++GSI + + + T+ I L + +
Sbjct: 1531 --------FRDAWNVF----DFVTVLGSITDILVTEIAETNN---FINLSFLRLFRAARL 1575
Query: 389 IRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPY----------H 438
I+ L +L+ T + + C AM++ Y G V G H
Sbjct: 1576 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRH 1635
Query: 439 DKFRSLNMVSECLFSLINGDDMFATFA---------KMQQKSYLVWLFSRIYLYSFISLF 489
+ FR+ LF G+ + + F+ Y SFI L
Sbjct: 1636 NNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLC 1695
Query: 490 IYMILSLFIALITDTYE 506
+++L+LF+A+I D +E
Sbjct: 1696 SFLMLNLFVAVIMDNFE 1712
>gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I
subunit isoform b [Homo sapiens]
Length = 2188
Score = 31.6 bits (70), Expect = 2.0
Identities = 54/269 (20%), Positives = 109/269 (40%), Gaps = 33/269 (12%)
Query: 282 THYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVN------FFLLHYKKEVSVSDQM 335
+HY+ IF F+I +V++ L + L+ ++ N F L K V+ +
Sbjct: 1451 SHYLDIFITFIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRR 1510
Query: 336 EFVNGWYIMIIISDILTIIGSIL-KMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGF 394
F + W + + +L+++G L ++EI A + + ++ +L V++ L
Sbjct: 1511 FFKDRWNQLDLAIVLLSVMGITLEEIEINA----ALPINPTIIRIMRVLRIARVLKLLKM 1566
Query: 395 FAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPY-------------HDKF 441
L+ T+ ALP V +++ Y G + G H F
Sbjct: 1567 ATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATF 1626
Query: 442 RSLNMVSECLFSLINGDDMFATF------AKMQQKSYL--VWLFSRIYLYSFISLFIYMI 493
+ M LF + GD+ ++S L + S +Y SF+ +++
Sbjct: 1627 ENFGMAFLTLFQVSTGDNWNGIMKDTLRDCTHDERSCLSSLQFVSPLYFVSFVLTAQFVL 1686
Query: 494 LSLFIA-LITDTYETIKQYQQDGFPETEL 521
+++ +A L+ ++ K+ Q+D + EL
Sbjct: 1687 INVVVAVLMKHLDDSNKEAQEDAEMDAEL 1715
>gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I
subunit isoform a [Homo sapiens]
Length = 2223
Score = 31.6 bits (70), Expect = 2.0
Identities = 54/269 (20%), Positives = 109/269 (40%), Gaps = 33/269 (12%)
Query: 282 THYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVN------FFLLHYKKEVSVSDQM 335
+HY+ IF F+I +V++ L + L+ ++ N F L K V+ +
Sbjct: 1486 SHYLDIFITFIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRR 1545
Query: 336 EFVNGWYIMIIISDILTIIGSIL-KMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGF 394
F + W + + +L+++G L ++EI A + + ++ +L V++ L
Sbjct: 1546 FFKDRWNQLDLAIVLLSVMGITLEEIEINA----ALPINPTIIRIMRVLRIARVLKLLKM 1601
Query: 395 FAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPY-------------HDKF 441
L+ T+ ALP V +++ Y G + G H F
Sbjct: 1602 ATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATF 1661
Query: 442 RSLNMVSECLFSLINGDDMFATF------AKMQQKSYL--VWLFSRIYLYSFISLFIYMI 493
+ M LF + GD+ ++S L + S +Y SF+ +++
Sbjct: 1662 ENFGMAFLTLFQVSTGDNWNGIMKDTLRDCTHDERSCLSSLQFVSPLYFVSFVLTAQFVL 1721
Query: 494 LSLFIA-LITDTYETIKQYQQDGFPETEL 521
+++ +A L+ ++ K+ Q+D + EL
Sbjct: 1722 INVVVAVLMKHLDDSNKEAQEDAEMDAEL 1750
>gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens]
Length = 809
Score = 31.6 bits (70), Expect = 2.0
Identities = 18/85 (21%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 331 VSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIR 390
+ +++FV G I++ +++ + K ++ S+ +D+C + G + M +++
Sbjct: 271 IQPRLQFVRGGDIIVDSNELRKHYRTSTKFQLDVASIIPFDICYLFFGFNPMFRANRMLK 330
Query: 391 YLGFFA-KYNLLILTLQAALPNVIR 414
Y FF ++L + +A + VIR
Sbjct: 331 YTSFFEFNHHLESIMDKAYIYRVIR 355
>gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo
sapiens]
Length = 2506
Score = 31.2 bits (69), Expect = 2.6
Identities = 13/30 (43%), Positives = 21/30 (70%)
Query: 477 FSRIYLYSFISLFIYMILSLFIALITDTYE 506
F+ Y SFI L +++L+LF+A+I D +E
Sbjct: 1785 FAYFYFVSFIFLCSFLMLNLFVAVIMDNFE 1814
>gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo
sapiens]
Length = 2261
Score = 31.2 bits (69), Expect = 2.6
Identities = 13/30 (43%), Positives = 21/30 (70%)
Query: 477 FSRIYLYSFISLFIYMILSLFIALITDTYE 506
F+ Y SFI L +++L+LF+A+I D +E
Sbjct: 1786 FAYFYFVSFIFLCSFLMLNLFVAVIMDNFE 1815
>gi|169206328 PREDICTED: hypothetical protein [Homo sapiens]
Length = 359
Score = 30.8 bits (68), Expect = 3.4
Identities = 10/37 (27%), Positives = 24/37 (64%)
Query: 475 WLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQY 511
+++ +Y+Y++I +++Y+ + + I + T TY I Y
Sbjct: 92 YMYIYVYIYTYIQIYVYICIYIHIYMYTHTYICIHIY 128
>gi|219689113 two pore segment channel 1 isoform 1 [Homo sapiens]
Length = 888
Score = 30.4 bits (67), Expect = 4.4
Identities = 13/49 (26%), Positives = 29/49 (59%)
Query: 462 ATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQ 510
A F + SY +S ++ ++S+ +Y I++L +A++ DT+ I++
Sbjct: 352 ANFPDVMMPSYSRNPWSCVFFIVYLSIELYFIMNLLLAVVFDTFNDIEK 400
>gi|29725622 two pore segment channel 1 isoform 2 [Homo sapiens]
Length = 816
Score = 30.4 bits (67), Expect = 4.4
Identities = 13/49 (26%), Positives = 29/49 (59%)
Query: 462 ATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQ 510
A F + SY +S ++ ++S+ +Y I++L +A++ DT+ I++
Sbjct: 280 ANFPDVMMPSYSRNPWSCVFFIVYLSIELYFIMNLLLAVVFDTFNDIEK 328
>gi|24119274 voltage gated channel like 1 [Homo sapiens]
Length = 1738
Score = 30.4 bits (67), Expect = 4.4
Identities = 31/162 (19%), Positives = 60/162 (37%), Gaps = 31/162 (19%)
Query: 370 YDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFC 429
+ +C + +L+ + V Y FF + +L L A V+ F
Sbjct: 1312 FSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLF-------------- 1357
Query: 430 GWIVLGP---YHDKFRSLNMVSECLFSLINGDD---------MFATFAKMQQKSYLV--- 474
G + G H F S LF ++ G+D + F + +Y
Sbjct: 1358 GTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDC 1417
Query: 475 --WLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQD 514
+ + +Y SF + Y++L+L +A+I + + ++D
Sbjct: 1418 GNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEED 1459
>gi|169210316 PREDICTED: hypothetical protein [Homo sapiens]
Length = 365
Score = 30.0 bits (66), Expect = 5.8
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 6/81 (7%)
Query: 474 VWLFSRIYLYS--FISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISE--CK 529
V+++ IY+Y ++ +++YM + ++I + Y I Y G PE C
Sbjct: 252 VYMYICIYVYVCIYVYIYVYMCIYVYICIYMCIYVYICVYMSPG-PEKSSEDISKRLVCD 310
Query: 530 DL-PNSGKYRLEDDPPVSLFC 549
L P GK + EDD S C
Sbjct: 311 FLRPKQGKLQAEDDWQGSTVC 331
>gi|188035871 SET and MYND domain containing 2 [Homo sapiens]
Length = 433
Score = 30.0 bits (66), Expect = 5.8
Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 147 ENKGTKQSAMAICQHFYKRGNIYPGNDTFDI-DPEIETECFFVEPDEPFHIGT 198
E K QS +A HFY + +P ND+ + ++ F +E +E H+G+
Sbjct: 144 EKKDLIQSDIAALHHFYSKHLGFPDNDSLVVLFAQVNCNGFTIEDEELSHLGS 196
>gi|20070163 voltage-dependent calcium channel alpha 1G subunit
isoform 1 [Homo sapiens]
Length = 2377
Score = 29.6 bits (65), Expect = 7.5
Identities = 7/35 (20%), Positives = 23/35 (65%)
Query: 480 IYLYSFISLFIYMILSLFIALITDTYETIKQYQQD 514
+Y SF+ + + +L++F+ ++ + + +Q+Q++
Sbjct: 1515 LYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEE 1549
>gi|38505292 voltage-dependent calcium channel alpha 1G subunit
isoform 3 [Homo sapiens]
Length = 2343
Score = 29.6 bits (65), Expect = 7.5
Identities = 7/35 (20%), Positives = 23/35 (65%)
Query: 480 IYLYSFISLFIYMILSLFIALITDTYETIKQYQQD 514
+Y SF+ + + +L++F+ ++ + + +Q+Q++
Sbjct: 1492 LYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEE 1526
>gi|38505290 voltage-dependent calcium channel alpha 1G subunit
isoform 13 [Homo sapiens]
Length = 2243
Score = 29.6 bits (65), Expect = 7.5
Identities = 7/35 (20%), Positives = 23/35 (65%)
Query: 480 IYLYSFISLFIYMILSLFIALITDTYETIKQYQQD 514
+Y SF+ + + +L++F+ ++ + + +Q+Q++
Sbjct: 1492 LYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEE 1526
>gi|38505288 voltage-dependent calcium channel alpha 1G subunit
isoform 12 [Homo sapiens]
Length = 2250
Score = 29.6 bits (65), Expect = 7.5
Identities = 7/35 (20%), Positives = 23/35 (65%)
Query: 480 IYLYSFISLFIYMILSLFIALITDTYETIKQYQQD 514
+Y SF+ + + +L++F+ ++ + + +Q+Q++
Sbjct: 1492 LYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEE 1526
>gi|38505286 voltage-dependent calcium channel alpha 1G subunit
isoform 10 [Homo sapiens]
Length = 2266
Score = 29.6 bits (65), Expect = 7.5
Identities = 7/35 (20%), Positives = 23/35 (65%)
Query: 480 IYLYSFISLFIYMILSLFIALITDTYETIKQYQQD 514
+Y SF+ + + +L++F+ ++ + + +Q+Q++
Sbjct: 1515 LYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEE 1549
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.141 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,598,418
Number of Sequences: 37866
Number of extensions: 803982
Number of successful extensions: 2717
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2627
Number of HSP's gapped (non-prelim): 85
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.