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Search of human proteins with 24307991
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24307991 p53-associated parkin-like cytoplasmic protein
[Homo sapiens]
(2517 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 5105 0.0
gi|41872646 cullin 7 [Homo sapiens] 1336 0.0
gi|5453557 ariadne homolog 2 [Homo sapiens] 177 1e-43
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 149 3e-35
gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa... 136 3e-31
gi|126032348 hect domain and RLD 2 [Homo sapiens] 95 8e-19
gi|157738609 HECT domain containing 3 [Homo sapiens] 94 2e-18
gi|73747881 zinc finger, ZZ type with EF hand domain 1 [Homo sap... 93 4e-18
gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 91 2e-17
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 91 2e-17
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 91 2e-17
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 91 2e-17
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 91 2e-17
gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 89 5e-17
gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 89 7e-17
gi|35493801 ring finger protein 19 [Homo sapiens] 83 4e-15
gi|35493782 ring finger protein 19 [Homo sapiens] 83 4e-15
gi|38045938 ring finger protein 144 [Homo sapiens] 77 3e-13
gi|169790973 parkin isoform 3 [Homo sapiens] 67 2e-10
gi|169790971 parkin isoform 2 [Homo sapiens] 67 2e-10
gi|169790969 parkin isoform 1 [Homo sapiens] 67 2e-10
gi|50284696 IBR domain containing 2 [Homo sapiens] 65 6e-10
gi|109150431 ring finger protein 31 [Homo sapiens] 59 8e-08
gi|115529449 upstream binding transcription factor, RNA polymera... 56 5e-07
gi|115529451 upstream binding transcription factor, RNA polymera... 56 5e-07
gi|7657671 upstream binding transcription factor, RNA polymerase... 56 5e-07
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 55 7e-07
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 55 7e-07
gi|22749145 ring finger protein 217 [Homo sapiens] 55 1e-06
gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ... 49 8e-05
>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
sapiens]
Length = 2517
Score = 5105 bits (13243), Expect = 0.0
Identities = 2517/2517 (100%), Positives = 2517/2517 (100%)
Query: 1 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 60
MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
Sbjct: 1 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 60
Query: 61 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 120
EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
Sbjct: 61 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 120
Query: 121 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 180
ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
Sbjct: 121 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 180
Query: 181 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 240
QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
Sbjct: 181 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 240
Query: 241 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 300
MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
Sbjct: 241 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 300
Query: 301 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 360
EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
Sbjct: 301 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 360
Query: 361 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 420
WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
Sbjct: 361 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 420
Query: 421 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 480
QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
Sbjct: 421 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 480
Query: 481 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 540
LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
Sbjct: 481 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 540
Query: 541 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 600
VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
Sbjct: 541 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 600
Query: 601 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 660
EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
Sbjct: 601 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 660
Query: 661 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 720
ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
Sbjct: 661 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 720
Query: 721 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 780
RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
Sbjct: 721 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 780
Query: 781 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 840
MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
Sbjct: 781 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 840
Query: 841 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 900
PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
Sbjct: 841 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 900
Query: 901 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 960
SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
Sbjct: 901 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 960
Query: 961 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 1020
AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
Sbjct: 961 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 1020
Query: 1021 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1080
RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
Sbjct: 1021 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1080
Query: 1081 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1140
KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
Sbjct: 1081 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1140
Query: 1141 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1200
HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
Sbjct: 1141 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1200
Query: 1201 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1260
GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
Sbjct: 1201 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1260
Query: 1261 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1320
VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
Sbjct: 1261 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1320
Query: 1321 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1380
RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
Sbjct: 1321 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1380
Query: 1381 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP 1440
QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
Sbjct: 1381 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP 1440
Query: 1441 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR 1500
EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
Sbjct: 1441 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR 1500
Query: 1501 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGG 1560
YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGG
Sbjct: 1501 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGG 1560
Query: 1561 LIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQ 1620
LIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQ
Sbjct: 1561 LIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQ 1620
Query: 1621 IGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEE 1680
IGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEE
Sbjct: 1621 IGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEE 1680
Query: 1681 EAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQN 1740
EAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQN
Sbjct: 1681 EAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQN 1740
Query: 1741 HPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLS 1800
HPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLS
Sbjct: 1741 HPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLS 1800
Query: 1801 PELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKD 1860
PELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKD
Sbjct: 1801 PELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKD 1860
Query: 1861 EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVA 1920
EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVA
Sbjct: 1861 EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVA 1920
Query: 1921 CTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSP 1980
CTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSP
Sbjct: 1921 CTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSP 1980
Query: 1981 EAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQ 2040
EAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQ
Sbjct: 1981 EAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQ 2040
Query: 2041 SYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEY 2100
SYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEY
Sbjct: 2041 SYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEY 2100
Query: 2101 LTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWC 2160
LTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWC
Sbjct: 2101 LTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWC 2160
Query: 2161 TNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMS 2220
TNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMS
Sbjct: 2161 TNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMS 2220
Query: 2221 VEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS 2280
VEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS
Sbjct: 2221 VEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS 2280
Query: 2281 AMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE 2340
AMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE
Sbjct: 2281 AMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE 2340
Query: 2341 QARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLL 2400
QARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLL
Sbjct: 2341 QARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLL 2400
Query: 2401 RADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGP 2460
RADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGP
Sbjct: 2401 RADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGP 2460
Query: 2461 EAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD 2517
EAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD
Sbjct: 2461 EAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD 2517
>gi|41872646 cullin 7 [Homo sapiens]
Length = 1698
Score = 1336 bits (3457), Expect = 0.0
Identities = 677/1065 (63%), Positives = 827/1065 (77%), Gaps = 32/1065 (3%)
Query: 918 MMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGG--PSAELLLDLERVLCREG 975
++LL+ ++ S + A +E Q SP ++ LV G P+ ++LLDLE+ L EG
Sbjct: 589 VLLLDAQAQAKDSEDAAKVEAKEPPSQ--SPNTPLQRLVEGYGPAGKILLDLEQALSSEG 646
Query: 976 SPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHE 1035
+ V+PLL +LQ++ QPFL L+++LD P N+TL L+VLR++ +L+DFPEA++LPWHE
Sbjct: 647 TQENKVKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHE 706
Query: 1036 VLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQL 1095
++ C+ CL P++D E++QEL FLHRL S+ +DYAVVL LGA++ +SK L+KH +L
Sbjct: 707 AVDACMACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKL 766
Query: 1096 LLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRH 1155
L ELRD+V +CEK+A LY L ++IL GCIQMVLGQIEDHRRTHQPINIPFFDVFLR+
Sbjct: 767 ELAQELRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDHRRTHQPINIPFFDVFLRY 826
Query: 1156 LCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLV 1215
LCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGS GSHYITLHM RG+L+
Sbjct: 827 LCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILI 886
Query: 1216 RQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQ 1275
RQLTLLVASEDSSYMPARVVV GGDSTS + TELN+VNVMPSASRVILLENL RFWPIIQ
Sbjct: 887 RQLTLLVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQ 946
Query: 1276 IRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRR 1335
IRIKRCQQGGIDTR+RG+E+LGPKPTFWP+FREQLCR T LFY +RAQAWS+D+AED R
Sbjct: 947 IRIKRCQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRS 1006
Query: 1336 LLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALG 1395
LL L RLN LR EQNFADRFLPDDEAAQALGKTCWEALVSP+VQNITSPD +G+S LG
Sbjct: 1007 LLHLSSRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLG 1066
Query: 1396 WLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSPEPST-RPFSKNSKGR 1454
WLLDQYLE +E NP SR +F SRVRRL HLLVHVEP P P +T RP +N +
Sbjct: 1067 WLLDQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRN-RSH 1125
Query: 1455 DRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSE 1514
D S + LPSS +RN+T+CW +VV++QV+ FL ++WR DFVPRYC+ + LQ + SE
Sbjct: 1126 DWSSLATRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSE 1185
Query: 1515 LFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGGLIGGAPGVEMLGQL 1574
LFGPRAAF+LAL++G +GALL+ FL AAH+SEQFAR+IDQQIQG IGGA +E L QL
Sbjct: 1186 LFGPRAAFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQL 1245
Query: 1575 QRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQLML 1634
Q+ L+ +++ SGLE+ATTFEH+YQHYMADRLL SSWLEGAVLEQIG CFPNRLPQ ML
Sbjct: 1246 QQCLQAVLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQML 1305
Query: 1635 QSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEK------------RLEEEEEE------ 1676
QSLSTS+ELQRQFH++QLQ+LD+ L+ ED E+K + E+EEE
Sbjct: 1306 QSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVV 1365
Query: 1677 -----EEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRF 1731
EEEEE ++L+ E P +S+LVLS WPV+ +C+ +PR CLP+ L+R+
Sbjct: 1366 DVAEGEEEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRY 1425
Query: 1732 SSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVE 1791
S+FY++SQ+HP L+ G RRLQWTWLG AELQFG Q LHVSTVQMWLLL N + VSVE
Sbjct: 1426 SNFYNKSQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVE 1485
Query: 1792 TLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPG--PQRSGEALWLI 1849
+LL S LS ++L QA+ PLTS GPL LHE +D P GGVL++ + P+ + + LI
Sbjct: 1486 SLLAFSGLSADMLNQAIGPLTSSRGPLDLHEQKDIP-GGVLKIRDGSKEPRSRWDIVRLI 1544
Query: 1850 PPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPG 1909
PPQ YL E ++G+ LE++RNLL+CL+VRILKAHG++GLHIDQLVCLVLEAWQKGP PP
Sbjct: 1545 PPQTYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPR 1604
Query: 1910 TLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAP 1954
L ++ G AC+STDVLSCILHLLG+G ++R DDRPQ+L YA P
Sbjct: 1605 GLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVLSYAVP 1649
Score = 607 bits (1566), Expect = e-173
Identities = 342/637 (53%), Positives = 434/637 (68%), Gaps = 29/637 (4%)
Query: 1 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGK--VGVEEG 58
MVGE + VPLGP L AYP+ELIRQR GHDGHPEY IRW +L+ G+ G G +
Sbjct: 1 MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC 60
Query: 59 KAEHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEAD 118
KAEHIL+W+S E+YANC +LGE G E AG + G LD+ + EME D
Sbjct: 61 KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAG-------EVGALDKSVLEEMETD 113
Query: 119 VQALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNP 178
V++L++RA RQL E A +LHT+HVLSAYASI PLTGVF++ LDLLMHML +P
Sbjct: 114 VKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSP 173
Query: 179 EPQIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEE 238
+ QIR SAG+M+QAL++HDAG+R +LLSLSQQ+ IE+H+DFDSR LL LFA+ T S E
Sbjct: 174 DYQIRWSAGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLS-E 232
Query: 239 HCMAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLN-SSPELGAGDQSSPCATREKSRGQ 297
H M+FEGI LPQ+PG++LFSLVKRYL VTSLLDQLN S+ E GA + S+P RGQ
Sbjct: 233 HPMSFEGIQLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAP-EELSGERGQ 291
Query: 298 RELEFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPR 357
ELEFSMA+G LISELV++M W + S++ S R SIFQP ++ S LP P
Sbjct: 292 LELEFSMAMGTLISELVQAMRWDQ-ASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPS 350
Query: 358 -RQGWVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPV 416
R+ FR RSEF+S + Y YV+ TLQPGMRVRMLDDYEEISAGDEGEFRQSNNG+PPV
Sbjct: 351 FRRSRRFRPRSEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPV 410
Query: 417 QVFWQSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGAT-VLGTAFPSWDWNPMDGL 475
QVFW+STGRTYWVHWHMLEILG EE ED A +GA A+ VLG A P+W W PM L
Sbjct: 411 QVFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTEL 470
Query: 476 YPLPYLQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLD-ETLGEKAL 534
Y +PY+ PE + E +LT AEWWELLFFIKKLD + Q + Q L +NLD E L ++ L
Sbjct: 471 YAVPYVLPEDEDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEIL 530
Query: 535 GEISVSVEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDP 594
E++V +E+A+ LL L R S L DL+N +Y KYG P + + ++ + +
Sbjct: 531 AELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKYG-----PEALAGNQAYPSLLEA 585
Query: 595 EE-----ESKSEASFSEEETESLKAKAEAPKTEAEPT 626
+E +++++A SE ++ K +A+ P +++ T
Sbjct: 586 QEDVLLLDAQAQAKDSE---DAAKVEAKEPPSQSPNT 619
>gi|5453557 ariadne homolog 2 [Homo sapiens]
Length = 493
Score = 177 bits (449), Expect = 1e-43
Identities = 108/407 (26%), Positives = 181/407 (44%), Gaps = 33/407 (8%)
Query: 2000 QEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQ 2059
+E EG + + + + L + VA+ +L + HW ++L Y + LL+ A + +
Sbjct: 67 KESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEARVQPNP 126
Query: 2060 AQAVPVR--PDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPI 2117
++ VP P HC VC+ + ++L SL C H C+SCW ++ + ++ + + +C
Sbjct: 127 SKHVPTSHPPHHCAVCMQFVR-KENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMA 185
Query: 2118 ADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGC 2177
DCP + F+ ++ + E+ KY + L R YVES L C I ++
Sbjct: 186 QDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRAR 245
Query: 2178 GTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCP 2237
C++C CF C H P C + +W+ + ++++ + +K CP
Sbjct: 246 RVQCNRCNEVFCFKCR-QMYHAPTDCATIRKWLTK------CADDSETANYISAHTKDCP 298
Query: 2238 SCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS-----------AMVSKA 2286
C IEKN GC HM C+KC H FCW CL WK + +YY CS + ++A
Sbjct: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQA 358
Query: 2287 ARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPR---------SFTFLNDACQ 2337
K++ Y ER H+++ + R IHE R + +L +A +
Sbjct: 359 REALKKYLFYFERWENHNKSLQLEAQTYQR---IHEKIQERVMNNLGTWIDWQYLQNAAK 415
Query: 2338 GLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLE 2384
L + R L Y Y++Y + + E Q LE L +E
Sbjct: 416 LLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVE 462
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding protein
homolog 1 [Homo sapiens]
Length = 557
Score = 149 bits (377), Expect = 3e-35
Identities = 117/453 (25%), Positives = 190/453 (41%), Gaps = 43/453 (9%)
Query: 1997 MSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLC 2056
++ +++ M + +R+V E + + + LL+H +W E+L++ Y + L A
Sbjct: 104 LTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHV 163
Query: 2057 VHQAQAVPVRPDHCPVCVSPLGC--------DDDLPSLCCMHYCCKSCWNEYLTTRI-EQ 2107
++ ++ R + + C + L C H C CW+EYLTT+I E+
Sbjct: 164 INPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEE 223
Query: 2108 NLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCD 2167
+ +CP C + +++ +V KY+ + +VE L WC P C
Sbjct: 224 GMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPD-CH 282
Query: 2168 RILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWV---DDGGYYDGMSVEAQ 2224
++ Q KCG CFNC H P C + +W+ DD +++
Sbjct: 283 HVVKVQYPDAKPVRCKCGRQFCFNCG-ENWHDPVKCKWLKKWIKKCDD---------DSE 332
Query: 2225 SKHLAKLISKRCPSCQAPIEKNEGCLHMTCAK--CNHGFCWRCLKSWKPNHKDYYNCSAM 2282
+ + +K CP C IEK+ GC HM C C FCW CL W+P+ +YNC+
Sbjct: 333 TSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRY 392
Query: 2283 ---VSKAAR--QEK------RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFT- 2330
+KAAR QE+ R+ Y R H Q+ F L +V E + +
Sbjct: 393 NEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSW 452
Query: 2331 ----FLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEET 2386
FL A L Q R L Y V++FY + + E +LE T L LE
Sbjct: 453 IEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERD 512
Query: 2387 LLR--CRDLASSLRLLRADCLSTGMELLRRIQE 2417
+ + +D+ ++ C S LL+ + E
Sbjct: 513 ISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHE 545
>gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo
sapiens]
Length = 1089
Score = 136 bits (342), Expect = 3e-31
Identities = 117/497 (23%), Positives = 200/497 (40%), Gaps = 96/497 (19%)
Query: 1997 MSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLC 2056
+ PQ++ L + + + L A+ LL W E+LL+++ +PE +G+
Sbjct: 228 LRPQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQ 287
Query: 2057 V--------------------HQAQAVPVRPDH------------CPVCVSPLGCDDDLP 2084
+ ++ PD C +C+ + +D
Sbjct: 288 MPTPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPV 347
Query: 2085 SLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEK 2144
+ C H C+ CW +L +I++ N CP DC I ++VS E+ +Y +
Sbjct: 348 DMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVVSK-EMDKRYLQ 406
Query: 2145 ALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTT----------------CSKCGWAS 2188
++ +VE+ + WC P GCDR + G T+ C K G
Sbjct: 407 FDIKAFVENNPAIKWCPTP-GCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGK-GHLF 464
Query: 2189 CFNCSFPEAHYPASCGHMSQW---VDDGGYYDGMSVEAQSKHLAKLI-----SKRCPSCQ 2240
C+ C EAH P C W + + + + V + A + SK C +C+
Sbjct: 465 CWEC-LGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCK 523
Query: 2241 APIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKD---YYNCS-------------AMVS 2284
+PI+KNEGC HM CAKC + FCW CL+ WK + YY C+ M
Sbjct: 524 SPIQKNEGCNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTV 583
Query: 2285 KAARQEKRFQDYNERCTFHHQAR--EFAVNLRNRV------------SAIHEVPPP-RSF 2329
+A ++ KRFQ+ + ++ + + E + L R+ A+ E
Sbjct: 584 EAEKKHKRFQELDRFMHYYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDT 643
Query: 2330 TFLNDACQGLEQARKVLAYACVYSFYSQ-DAEYMDVVEQQTENLELHTNALQILLEETLL 2388
TF+ DA L + R++L + Y F+ + + ++ E +LE+ T L + L
Sbjct: 644 TFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYL 703
Query: 2389 RCRDLASSLRLLRADCL 2405
R ++++A CL
Sbjct: 704 R----TPRHKIIKAACL 716
>gi|126032348 hect domain and RLD 2 [Homo sapiens]
Length = 4834
Score = 95.1 bits (235), Expect = 8e-19
Identities = 52/127 (40%), Positives = 83/127 (65%), Gaps = 2/127 (1%)
Query: 1171 EKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYM 1230
+ + VSS+ ++AS+L D + + W+S+GS G H+I L + VLV +L ++V DSSYM
Sbjct: 2787 KSLNVSSSVNQASRLIDGS-EPCWQSSGSQGKHWIRLEIFPDVLVHRLKMIVDPADSSYM 2845
Query: 1231 PARVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRV 1290
P+ VVV GG+S + + EL T+N+ PS + V LL + + I+I IK+C+ GID ++
Sbjct: 2846 PSLVVVSGGNSLNNL-IELKTININPSDTTVPLLNDCTEYHRYIEIAIKQCRSSGIDCKI 2904
Query: 1291 RGVEVLG 1297
G+ +LG
Sbjct: 2905 HGLILLG 2911
Score = 59.7 bits (143), Expect = 4e-08
Identities = 36/113 (31%), Positives = 56/113 (49%), Gaps = 11/113 (9%)
Query: 363 FRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGE-FRQSNNGIPP--VQVF 419
+++R++F S Y YV++ +Q GM VR YEE+ GD G+ + +G+ VQ
Sbjct: 2551 YKKRADFLSNDDYAVYVRENIQVGMMVRCCRAYEEVCEGDVGKVIKLDRDGLHDLNVQCD 2610
Query: 420 WQSTGRTYWVHWHMLEILG---PEEATEDKASAAVEKGAGATVLGTAFPSWDW 469
WQ G TYWV + +E++G P ++ K V A T P + W
Sbjct: 2611 WQQKGGTYWVRYIHVELIGYPPPSSSSHIKIGDKVRVKASVTT-----PKYKW 2658
>gi|157738609 HECT domain containing 3 [Homo sapiens]
Length = 861
Score = 93.6 bits (231), Expect = 2e-18
Identities = 52/128 (40%), Positives = 80/128 (62%), Gaps = 5/128 (3%)
Query: 1171 EKVEVSS--NPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSS 1228
E ++VSS S LTD N TYWES+GS H++ L M +G +V++L L V + D +
Sbjct: 245 ESIDVSSYTEEFNVSCLTDSNADTYWESDGSQCQHWVRLTMKKGTIVKKLLLTVDTTDDN 304
Query: 1229 YMPARVVVFGGDSTSCIGTELNTVNVMPS-ASRVILLENLNRFWPIIQIRIKRCQQGGID 1287
+MP RVVV+GG+ + +L+ V++ + V +LE++ PII+IRI C+ GID
Sbjct: 305 FMPKRVVVYGGEGDNL--KKLSDVSIDETLIGDVCVLEDMTVHLPIIEIRIVECRDDGID 362
Query: 1288 TRVRGVEV 1295
R+RGV++
Sbjct: 363 VRLRGVKI 370
>gi|73747881 zinc finger, ZZ type with EF hand domain 1 [Homo sapiens]
Length = 2961
Score = 92.8 bits (229), Expect = 4e-18
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 2/131 (1%)
Query: 1168 KCWEKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDS 1227
KC+ +E SSN K+T+ +YW+S+GS SH+I L M V++R L++ VA+ D
Sbjct: 251 KCYAYIETSSNSADIDKMTNGETSSYWQSDGSACSHWIRLKMKPDVVLRHLSIAVAATDQ 310
Query: 1228 SYMPARVVVFGGDSTSCIGTELNTVNVMPSAS-RVILLENLNRFWPIIQIRIKRCQQGGI 1286
SYMP +V V G + S + E+ V++ + + V LLEN N +QI IKRC G
Sbjct: 311 SYMPQQVTVAVGRNASDL-QEVRDVHIPSNVTGYVTLLENANVSQLYVQINIKRCLSDGC 369
Query: 1287 DTRVRGVEVLG 1297
DTR+ G+ +G
Sbjct: 370 DTRIHGLRAVG 380
>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 90.5 bits (223), Expect = 2e-17
Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
C +C + + L C H CK+C +Y +I V CP CP+ T +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188
+ +V + E+ ++Y++ LL+ ++ +++ +C P+ C ++ Q GC CS C +A
Sbjct: 280 KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 336
Query: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227
C C H + C ++ + D Y E +SK
Sbjct: 337 CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395
Query: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268
+ SK CP C PIEK +GC MTC C FCW C+ S
Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 436
>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 90.5 bits (223), Expect = 2e-17
Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
C +C + + L C H CK+C +Y +I V CP CP+ T +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188
+ +V + E+ ++Y++ LL+ ++ +++ +C P+ C ++ Q GC CS C +A
Sbjct: 280 KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 336
Query: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227
C C H + C ++ + D Y E +SK
Sbjct: 337 CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395
Query: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268
+ SK CP C PIEK +GC MTC C FCW C+ S
Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 436
>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 90.5 bits (223), Expect = 2e-17
Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
C +C + + L C H CK+C +Y +I V CP CP+ T +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188
+ +V + E+ ++Y++ LL+ ++ +++ +C P+ C ++ Q GC CS C +A
Sbjct: 280 KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 336
Query: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227
C C H + C ++ + D Y E +SK
Sbjct: 337 CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395
Query: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268
+ SK CP C PIEK +GC MTC C FCW C+ S
Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 436
>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
Length = 348
Score = 90.5 bits (223), Expect = 2e-17
Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
C +C + + L C H CK+C +Y +I V CP CP+ T +
Sbjct: 94 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153
Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188
+ +V + E+ ++Y++ LL+ ++ +++ +C P+ C ++ Q GC CS C +A
Sbjct: 154 KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 210
Query: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227
C C H + C ++ + D Y E +SK
Sbjct: 211 CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 269
Query: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268
+ SK CP C PIEK +GC MTC C FCW C+ S
Sbjct: 270 WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 310
>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 90.5 bits (223), Expect = 2e-17
Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
C +C + + L C H CK+C +Y +I V CP CP+ T +
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188
+ +V + E+ ++Y++ LL+ ++ +++ +C P+ C ++ Q GC CS C +A
Sbjct: 280 KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 336
Query: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227
C C H + C ++ + D Y E +SK
Sbjct: 337 CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395
Query: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268
+ SK CP C PIEK +GC MTC C FCW C+ S
Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 436
>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
Length = 587
Score = 89.0 bits (219), Expect = 5e-17
Identities = 63/217 (29%), Positives = 94/217 (43%), Gaps = 23/217 (10%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
CP+C+ L + L C H C+ C YL I ++ V +CP +C + I
Sbjct: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCP--ECSERLNPHDI 175
Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASC 2189
R +++ P ++ KYE+ +LR Y+ S + WC P C + G C+ C +C
Sbjct: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPD-CGYAVIAYG------CASCPKLTC 228
Query: 2190 FN--CSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLIS---------KRCPS 2238
C ++ H +Q D ++ ++KH + L K CP
Sbjct: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPR 288
Query: 2239 CQAPIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273
C A I K N+G C HMTCA C FCW C+K H
Sbjct: 289 CSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 325
>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
Length = 732
Score = 88.6 bits (218), Expect = 7e-17
Identities = 63/218 (28%), Positives = 94/218 (43%), Gaps = 24/218 (11%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
CP+C+ L + L C H C+ C YL I ++ V +CP +C + I
Sbjct: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCP--ECSERLNPHDI 175
Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASC 2189
R +++ P ++ KYE+ +LR Y+ S + WC P C + G C+ C +C
Sbjct: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPD-CGYAVIAYG------CASCPKLTC 228
Query: 2190 FN--CSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLIS----------KRCP 2237
C ++ H +Q D ++ ++KH + L K CP
Sbjct: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCP 288
Query: 2238 SCQAPIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273
C A I K N+G C HMTCA C FCW C+K H
Sbjct: 289 RCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 326
>gi|35493801 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 82.8 bits (203), Expect = 4e-15
Identities = 63/215 (29%), Positives = 93/215 (43%), Gaps = 17/215 (7%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
CP+C+ D + C H C C +YL I ++ V N +CP +C + I
Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRV-NISCP--ECTERFNPHDI 188
Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT----TCSK-- 2183
R I+S ++ KYE+ +LR ++ + + WC P ++ GC + TC +
Sbjct: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIA---FGCASCPKLTCGREG 245
Query: 2184 CGWASCFNCS---FPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQ 2240
CG C++C P A+ +Q + +Q A K CP C
Sbjct: 246 CGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCA 305
Query: 2241 APIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273
A I K N+G C HMTCA C FCW C+K H
Sbjct: 306 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 340
>gi|35493782 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 82.8 bits (203), Expect = 4e-15
Identities = 63/215 (29%), Positives = 93/215 (43%), Gaps = 17/215 (7%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
CP+C+ D + C H C C +YL I ++ V N +CP +C + I
Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRV-NISCP--ECTERFNPHDI 188
Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT----TCSK-- 2183
R I+S ++ KYE+ +LR ++ + + WC P ++ GC + TC +
Sbjct: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIA---FGCASCPKLTCGREG 245
Query: 2184 CGWASCFNCS---FPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQ 2240
CG C++C P A+ +Q + +Q A K CP C
Sbjct: 246 CGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCA 305
Query: 2241 APIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273
A I K N+G C HMTCA C FCW C+K H
Sbjct: 306 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 340
>gi|38045938 ring finger protein 144 [Homo sapiens]
Length = 292
Score = 76.6 bits (187), Expect = 3e-13
Identities = 55/205 (26%), Positives = 78/205 (38%), Gaps = 13/205 (6%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQP--TGA 2127
C +C+ + C C C +Y+ I++ L +CP A CP Q
Sbjct: 20 CKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQEN 79
Query: 2128 FIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTT----CSK 2183
I +V++ E++ +Y+K V TWC C + Q +G T C
Sbjct: 80 EIECMVAA-EIMQRYKKLQFEREVLFDPCRTWCP-ASTCQAVCQLQDVGLQTPQPVQCKA 137
Query: 2184 CGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPI 2243
C C C H C + G + A KRCP C+ I
Sbjct: 138 CRMEFCSTCK-ASWHPGQGCPETMPIT----FLPGETSAAFKMEEDDAPIKRCPKCKVYI 192
Query: 2244 EKNEGCLHMTCAKCNHGFCWRCLKS 2268
E++EGC M C C H FCW CL+S
Sbjct: 193 ERDEGCAQMMCKNCKHAFCWYCLES 217
>gi|169790973 parkin isoform 3 [Homo sapiens]
Length = 316
Score = 67.0 bits (162), Expect = 2e-10
Identities = 54/207 (26%), Positives = 80/207 (38%), Gaps = 37/207 (17%)
Query: 2090 HYCCKSCWNEYLTTRI-------EQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKY 2142
H C C++ Y TR+ + L + C +A CP + E ++Y
Sbjct: 108 HVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPC-VAGCPNSLIKELHHFRILGEEQYNRY 166
Query: 2143 EKALLRGYVESCSNLTWCTNPQGCD----------RILCRQGLGCGTTCSKCGWASCFNC 2192
++ V + C P GC ++ C G G G CG+A C C
Sbjct: 167 QQYGAEECVLQMGGVL-CPRP-GCGAGLLPEPDQRKVTCEGGNGLG-----CGFAFCREC 219
Query: 2193 SFPEAHYPASCGHMSQ--------WVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIE 2244
EA++ C + + + D + EA SK K +K CP C P+E
Sbjct: 220 K--EAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVE 277
Query: 2245 KNEGCLHMTC--AKCNHGFCWRCLKSW 2269
KN GC+HM C +C +CW C W
Sbjct: 278 KNGGCMHMKCPQPQCRLEWCWNCGCEW 304
>gi|169790971 parkin isoform 2 [Homo sapiens]
Length = 437
Score = 67.0 bits (162), Expect = 2e-10
Identities = 54/207 (26%), Positives = 80/207 (38%), Gaps = 37/207 (17%)
Query: 2090 HYCCKSCWNEYLTTRI-------EQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKY 2142
H C C++ Y TR+ + L + C +A CP + E ++Y
Sbjct: 229 HVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPC-VAGCPNSLIKELHHFRILGEEQYNRY 287
Query: 2143 EKALLRGYVESCSNLTWCTNPQGCD----------RILCRQGLGCGTTCSKCGWASCFNC 2192
++ V + C P GC ++ C G G G CG+A C C
Sbjct: 288 QQYGAEECVLQMGGVL-CPRP-GCGAGLLPEPDQRKVTCEGGNGLG-----CGFAFCREC 340
Query: 2193 SFPEAHYPASCGHMSQ--------WVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIE 2244
EA++ C + + + D + EA SK K +K CP C P+E
Sbjct: 341 K--EAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVE 398
Query: 2245 KNEGCLHMTC--AKCNHGFCWRCLKSW 2269
KN GC+HM C +C +CW C W
Sbjct: 399 KNGGCMHMKCPQPQCRLEWCWNCGCEW 425
>gi|169790969 parkin isoform 1 [Homo sapiens]
Length = 465
Score = 67.0 bits (162), Expect = 2e-10
Identities = 54/207 (26%), Positives = 80/207 (38%), Gaps = 37/207 (17%)
Query: 2090 HYCCKSCWNEYLTTRI-------EQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKY 2142
H C C++ Y TR+ + L + C +A CP + E ++Y
Sbjct: 257 HVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPC-VAGCPNSLIKELHHFRILGEEQYNRY 315
Query: 2143 EKALLRGYVESCSNLTWCTNPQGCD----------RILCRQGLGCGTTCSKCGWASCFNC 2192
++ V + C P GC ++ C G G G CG+A C C
Sbjct: 316 QQYGAEECVLQMGGVL-CPRP-GCGAGLLPEPDQRKVTCEGGNGLG-----CGFAFCREC 368
Query: 2193 SFPEAHYPASCGHMSQ--------WVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIE 2244
EA++ C + + + D + EA SK K +K CP C P+E
Sbjct: 369 K--EAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVE 426
Query: 2245 KNEGCLHMTC--AKCNHGFCWRCLKSW 2269
KN GC+HM C +C +CW C W
Sbjct: 427 KNGGCMHMKCPQPQCRLEWCWNCGCEW 453
>gi|50284696 IBR domain containing 2 [Homo sapiens]
Length = 303
Score = 65.5 bits (158), Expect = 6e-10
Identities = 52/211 (24%), Positives = 76/211 (36%), Gaps = 27/211 (12%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYC----CKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPT 2125
C +C+ C+ L + + C C +C +Y+ I + TCP C T
Sbjct: 30 CKLCL----CEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGT 85
Query: 2126 --GAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSK 2183
A I +V + Y++ V TWC C + C S
Sbjct: 86 LQEAEIACLVPVDQ-FQLYQRLKFEREVHLDPYRTWCPVAD-CQTV-------CPVASSD 136
Query: 2184 CGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLIS------KRCP 2237
G C P H W + D + ++H A + K+CP
Sbjct: 137 PGQPVLVEC--PSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCP 194
Query: 2238 SCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268
C+ IE+NEGC M C C H FCW CL++
Sbjct: 195 VCRVYIERNEGCAQMMCKNCKHTFCWYCLQN 225
>gi|109150431 ring finger protein 31 [Homo sapiens]
Length = 1072
Score = 58.5 bits (140), Expect = 8e-08
Identities = 47/223 (21%), Positives = 78/223 (34%), Gaps = 29/223 (13%)
Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129
C VC L + C C C+ ++ T +++ + + CP P +
Sbjct: 699 CAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQL 758
Query: 2130 RAIVSS----------PEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT 2179
+ S+ P+ + + K L G + WC C +
Sbjct: 759 LSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQ---CSFGFIYEREQLEA 815
Query: 2180 TCSKCGWASCFNCS--FPEAHYPASCGHMSQW--VDDGGYYDGMSVEAQSKHLAKLISKR 2235
TC +C C C + E H SC W ++D Y Q++ LA + +
Sbjct: 816 TCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEY--------QAQGLAMYLQEN 867
Query: 2236 ---CPSCQAPIE-KNEGCLHMTCAKCNHGFCWRCLKSWKPNHK 2274
CP C+ GC+H C +C H FC C ++ +K
Sbjct: 868 GIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNK 910
Score = 35.0 bits (79), Expect = 0.93
Identities = 27/125 (21%), Positives = 45/125 (36%), Gaps = 16/125 (12%)
Query: 2236 CPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQD 2295
C C L TC +C+ FC RC + W+ H+ R + FQ+
Sbjct: 799 CAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHR------------GRSCEDFQN 846
Query: 2296 YNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE--QARKVLAYACVYS 2353
+ +QA+ A+ L+ + I S+ C Q R C +
Sbjct: 847 WKRMNDPEYQAQGLAMYLQE--NGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNA 904
Query: 2354 FYSQD 2358
FY+++
Sbjct: 905 FYAKN 909
>gi|115529449 upstream binding transcription factor, RNA polymerase I
isoform b [Homo sapiens]
Length = 727
Score = 55.8 bits (133), Expect = 5e-07
Identities = 28/73 (38%), Positives = 43/73 (58%)
Query: 2445 KGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFF 2504
+GPN S+ S E+EE++E+DEDD E +++E DE D+ D SE+ ++
Sbjct: 623 RGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 682
Query: 2505 FGDEEEDEDEAYD 2517
GDE E++DE D
Sbjct: 683 DGDENEEDDEDED 695
Score = 36.6 bits (83), Expect = 0.32
Identities = 20/71 (28%), Positives = 35/71 (49%)
Query: 2443 EAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQET 2502
++K + + E EEEE+D+ D E D + +++S DE+E D++
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Query: 2503 FFFGDEEEDED 2513
D++EDED
Sbjct: 695 DDDEDDDEDED 705
Score = 34.7 bits (78), Expect = 1.2
Identities = 15/39 (38%), Positives = 26/39 (66%)
Query: 2451 GSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDS 2489
G ++SS E+E+ +E++EDD E ++ DE+ DN+S
Sbjct: 670 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708
Score = 32.0 bits (71), Expect = 7.9
Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 4/48 (8%)
Query: 2452 SQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLD 2499
S+ ++ G E EE++ED++DD + D+ DE+ +++ S S + D
Sbjct: 677 SEDESEDGDENEEDDEDEDDD----EDDDEDEDNESEGSSSSSSSSGD 720
>gi|115529451 upstream binding transcription factor, RNA polymerase I
isoform b [Homo sapiens]
Length = 727
Score = 55.8 bits (133), Expect = 5e-07
Identities = 28/73 (38%), Positives = 43/73 (58%)
Query: 2445 KGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFF 2504
+GPN S+ S E+EE++E+DEDD E +++E DE D+ D SE+ ++
Sbjct: 623 RGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 682
Query: 2505 FGDEEEDEDEAYD 2517
GDE E++DE D
Sbjct: 683 DGDENEEDDEDED 695
Score = 36.6 bits (83), Expect = 0.32
Identities = 20/71 (28%), Positives = 35/71 (49%)
Query: 2443 EAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQET 2502
++K + + E EEEE+D+ D E D + +++S DE+E D++
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Query: 2503 FFFGDEEEDED 2513
D++EDED
Sbjct: 695 DDDEDDDEDED 705
Score = 34.7 bits (78), Expect = 1.2
Identities = 15/39 (38%), Positives = 26/39 (66%)
Query: 2451 GSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDS 2489
G ++SS E+E+ +E++EDD E ++ DE+ DN+S
Sbjct: 670 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708
Score = 32.0 bits (71), Expect = 7.9
Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 4/48 (8%)
Query: 2452 SQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLD 2499
S+ ++ G E EE++ED++DD + D+ DE+ +++ S S + D
Sbjct: 677 SEDESEDGDENEEDDEDEDDD----EDDDEDEDNESEGSSSSSSSSGD 720
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 55.8 bits (133), Expect = 5e-07
Identities = 28/73 (38%), Positives = 43/73 (58%)
Query: 2445 KGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFF 2504
+GPN S+ S E+EE++E+DEDD E +++E DE D+ D SE+ ++
Sbjct: 660 RGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 719
Query: 2505 FGDEEEDEDEAYD 2517
GDE E++DE D
Sbjct: 720 DGDENEEDDEDED 732
Score = 36.6 bits (83), Expect = 0.32
Identities = 20/71 (28%), Positives = 35/71 (49%)
Query: 2443 EAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQET 2502
++K + + E EEEE+D+ D E D + +++S DE+E D++
Sbjct: 672 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731
Query: 2503 FFFGDEEEDED 2513
D++EDED
Sbjct: 732 DDDEDDDEDED 742
Score = 34.7 bits (78), Expect = 1.2
Identities = 15/39 (38%), Positives = 26/39 (66%)
Query: 2451 GSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDS 2489
G ++SS E+E+ +E++EDD E ++ DE+ DN+S
Sbjct: 707 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 745
Score = 32.0 bits (71), Expect = 7.9
Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 4/48 (8%)
Query: 2452 SQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLD 2499
S+ ++ G E EE++ED++DD + D+ DE+ +++ S S + D
Sbjct: 714 SEDESEDGDENEEDDEDEDDD----EDDDEDEDNESEGSSSSSSSSGD 757
>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 isoform
1 [Homo sapiens]
Length = 468
Score = 55.5 bits (132), Expect = 7e-07
Identities = 46/211 (21%), Positives = 77/211 (36%), Gaps = 29/211 (13%)
Query: 2067 PDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTG 2126
P CPVC S L + + C+H C+ C L I + +CP D +G
Sbjct: 237 PAECPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRNSQEAEVSCPFIDNTYSCSG 292
Query: 2127 AFIRAIVSSPEVISKYEKALLRGY--VESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKC 2184
+ + + Y++ L G E+ S ++ C + TC C
Sbjct: 293 KLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVC 352
Query: 2185 GWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISK---------- 2234
+C C H +C Y + +++ AQ+ A+ ++
Sbjct: 353 FHVNCLLCK--AIHEQMNCKE---------YQEDLALRAQNDVAARQTTEMLKVMLQQGE 401
Query: 2235 --RCPSCQAPIEKNEGCLHMTCAKCNHGFCW 2263
RCP CQ ++K +GC + C C+ CW
Sbjct: 402 AMRCPQCQIVVQKKDGCDWIRCTVCHTEICW 432
>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
isoform 2 [Homo sapiens]
Length = 510
Score = 55.5 bits (132), Expect = 7e-07
Identities = 46/211 (21%), Positives = 77/211 (36%), Gaps = 29/211 (13%)
Query: 2067 PDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTG 2126
P CPVC S L + + C+H C+ C L I + +CP D +G
Sbjct: 279 PAECPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRNSQEAEVSCPFIDNTYSCSG 334
Query: 2127 AFIRAIVSSPEVISKYEKALLRGY--VESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKC 2184
+ + + Y++ L G E+ S ++ C + TC C
Sbjct: 335 KLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVC 394
Query: 2185 GWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISK---------- 2234
+C C H +C Y + +++ AQ+ A+ ++
Sbjct: 395 FHVNCLLCK--AIHEQMNCKE---------YQEDLALRAQNDVAARQTTEMLKVMLQQGE 443
Query: 2235 --RCPSCQAPIEKNEGCLHMTCAKCNHGFCW 2263
RCP CQ ++K +GC + C C+ CW
Sbjct: 444 AMRCPQCQIVVQKKDGCDWIRCTVCHTEICW 474
>gi|22749145 ring finger protein 217 [Homo sapiens]
Length = 275
Score = 54.7 bits (130), Expect = 1e-06
Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
Query: 2181 CSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQ 2240
C C + CF C P H +C + D + +E ++ +++CP C+
Sbjct: 83 CPTCQFVWCFKCHSPW-HEGVNCKEYKKG-DKLLRHWASEIEHGQRN-----AQKCPKCK 135
Query: 2241 APIEKNEGCLHMTCAKCNHGFCWRC 2265
I++ EGC HMTC++CN FC+RC
Sbjct: 136 IHIQRTEGCDHMTCSQCNTNFCYRC 160
>gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein [Homo
sapiens]
Length = 593
Score = 48.5 bits (114), Expect = 8e-05
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 11/80 (13%)
Query: 2437 PSVEAWEAKGPNMPGSQPQASSGPEAEEEEE--DDEDDVPEWQQDEFDEELDNDSFSYDE 2494
P E +A PGS + GP E E+ DED P+W+++E +E+L D +E
Sbjct: 86 PGSEEEDAAREGTPGSPGRGREGPGEEHFEDMASDEDMKPKWEEEEMEEDLGED----EE 141
Query: 2495 SENLDQETFFFGDEEEDEDE 2514
E D E DEEE+EDE
Sbjct: 142 EEEEDYE-----DEEEEEDE 156
Score = 32.7 bits (73), Expect = 4.6
Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 1661 EQEDEEEKRLEEEEEEEE----EEEAEKELFIEDPSPA-ISILVLSPR 1703
E+E+ EE E+EEEEEE EEE E E + P PA + L PR
Sbjct: 128 EEEEMEEDLGEDEEEEEEDYEDEEEEEDEEGLGPPGPASLGTTALFPR 175
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,298,482
Number of Sequences: 37866
Number of extensions: 5452492
Number of successful extensions: 55283
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 309
Number of HSP's successfully gapped in prelim test: 191
Number of HSP's that attempted gapping in prelim test: 39257
Number of HSP's gapped (non-prelim): 11232
length of query: 2517
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2398
effective length of database: 13,741,464
effective search space: 32952030672
effective search space used: 32952030672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.