BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo sapiens] (2517 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 5105 0.0 gi|41872646 cullin 7 [Homo sapiens] 1336 0.0 gi|5453557 ariadne homolog 2 [Homo sapiens] 177 1e-43 gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 149 3e-35 gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa... 136 3e-31 gi|126032348 hect domain and RLD 2 [Homo sapiens] 95 8e-19 gi|157738609 HECT domain containing 3 [Homo sapiens] 94 2e-18 gi|73747881 zinc finger, ZZ type with EF hand domain 1 [Homo sap... 93 4e-18 gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 91 2e-17 gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 91 2e-17 gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 91 2e-17 gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 91 2e-17 gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 91 2e-17 gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 89 5e-17 gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 89 7e-17 gi|35493801 ring finger protein 19 [Homo sapiens] 83 4e-15 gi|35493782 ring finger protein 19 [Homo sapiens] 83 4e-15 gi|38045938 ring finger protein 144 [Homo sapiens] 77 3e-13 gi|169790973 parkin isoform 3 [Homo sapiens] 67 2e-10 gi|169790971 parkin isoform 2 [Homo sapiens] 67 2e-10 gi|169790969 parkin isoform 1 [Homo sapiens] 67 2e-10 gi|50284696 IBR domain containing 2 [Homo sapiens] 65 6e-10 gi|109150431 ring finger protein 31 [Homo sapiens] 59 8e-08 gi|115529449 upstream binding transcription factor, RNA polymera... 56 5e-07 gi|115529451 upstream binding transcription factor, RNA polymera... 56 5e-07 gi|7657671 upstream binding transcription factor, RNA polymerase... 56 5e-07 gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 55 7e-07 gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 55 7e-07 gi|22749145 ring finger protein 217 [Homo sapiens] 55 1e-06 gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ... 49 8e-05 >gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo sapiens] Length = 2517 Score = 5105 bits (13243), Expect = 0.0 Identities = 2517/2517 (100%), Positives = 2517/2517 (100%) Query: 1 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 60 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA Sbjct: 1 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA 60 Query: 61 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 120 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ Sbjct: 61 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ 120 Query: 121 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 180 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP Sbjct: 121 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP 180 Query: 181 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 240 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC Sbjct: 181 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC 240 Query: 241 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 300 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL Sbjct: 241 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL 300 Query: 301 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 360 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG Sbjct: 301 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG 360 Query: 361 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 420 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW Sbjct: 361 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW 420 Query: 421 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 480 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY Sbjct: 421 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY 480 Query: 481 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 540 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS Sbjct: 481 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS 540 Query: 541 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 600 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS Sbjct: 541 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS 600 Query: 601 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 660 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA Sbjct: 601 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA 660 Query: 661 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 720 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV Sbjct: 661 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV 720 Query: 721 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 780 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC Sbjct: 721 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC 780 Query: 781 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 840 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR Sbjct: 781 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR 840 Query: 841 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 900 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH Sbjct: 841 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH 900 Query: 901 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 960 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS Sbjct: 901 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS 960 Query: 961 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 1020 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT Sbjct: 961 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT 1020 Query: 1021 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1080 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA Sbjct: 1021 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA 1080 Query: 1081 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1140 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT Sbjct: 1081 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT 1140 Query: 1141 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1200 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST Sbjct: 1141 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST 1200 Query: 1201 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1260 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR Sbjct: 1201 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR 1260 Query: 1261 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1320 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI Sbjct: 1261 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI 1320 Query: 1321 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1380 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV Sbjct: 1321 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV 1380 Query: 1381 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP 1440 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP Sbjct: 1381 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP 1440 Query: 1441 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR 1500 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR Sbjct: 1441 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR 1500 Query: 1501 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGG 1560 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGG Sbjct: 1501 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGG 1560 Query: 1561 LIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQ 1620 LIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQ Sbjct: 1561 LIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQ 1620 Query: 1621 IGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEE 1680 IGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEE Sbjct: 1621 IGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEE 1680 Query: 1681 EAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQN 1740 EAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQN Sbjct: 1681 EAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQN 1740 Query: 1741 HPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLS 1800 HPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLS Sbjct: 1741 HPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLS 1800 Query: 1801 PELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKD 1860 PELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKD Sbjct: 1801 PELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKD 1860 Query: 1861 EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVA 1920 EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVA Sbjct: 1861 EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVA 1920 Query: 1921 CTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSP 1980 CTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSP Sbjct: 1921 CTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSP 1980 Query: 1981 EAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQ 2040 EAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQ Sbjct: 1981 EAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQ 2040 Query: 2041 SYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEY 2100 SYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEY Sbjct: 2041 SYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEY 2100 Query: 2101 LTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWC 2160 LTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWC Sbjct: 2101 LTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWC 2160 Query: 2161 TNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMS 2220 TNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMS Sbjct: 2161 TNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMS 2220 Query: 2221 VEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS 2280 VEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS Sbjct: 2221 VEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS 2280 Query: 2281 AMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE 2340 AMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE Sbjct: 2281 AMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE 2340 Query: 2341 QARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLL 2400 QARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLL Sbjct: 2341 QARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLL 2400 Query: 2401 RADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGP 2460 RADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGP Sbjct: 2401 RADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGP 2460 Query: 2461 EAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD 2517 EAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD Sbjct: 2461 EAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD 2517 >gi|41872646 cullin 7 [Homo sapiens] Length = 1698 Score = 1336 bits (3457), Expect = 0.0 Identities = 677/1065 (63%), Positives = 827/1065 (77%), Gaps = 32/1065 (3%) Query: 918 MMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGG--PSAELLLDLERVLCREG 975 ++LL+ ++ S + A +E Q SP ++ LV G P+ ++LLDLE+ L EG Sbjct: 589 VLLLDAQAQAKDSEDAAKVEAKEPPSQ--SPNTPLQRLVEGYGPAGKILLDLEQALSSEG 646 Query: 976 SPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHE 1035 + V+PLL +LQ++ QPFL L+++LD P N+TL L+VLR++ +L+DFPEA++LPWHE Sbjct: 647 TQENKVKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHE 706 Query: 1036 VLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQL 1095 ++ C+ CL P++D E++QEL FLHRL S+ +DYAVVL LGA++ +SK L+KH +L Sbjct: 707 AVDACMACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKL 766 Query: 1096 LLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRH 1155 L ELRD+V +CEK+A LY L ++IL GCIQMVLGQIEDHRRTHQPINIPFFDVFLR+ Sbjct: 767 ELAQELRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDHRRTHQPINIPFFDVFLRY 826 Query: 1156 LCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLV 1215 LCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGS GSHYITLHM RG+L+ Sbjct: 827 LCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILI 886 Query: 1216 RQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQ 1275 RQLTLLVASEDSSYMPARVVV GGDSTS + TELN+VNVMPSASRVILLENL RFWPIIQ Sbjct: 887 RQLTLLVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQ 946 Query: 1276 IRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRR 1335 IRIKRCQQGGIDTR+RG+E+LGPKPTFWP+FREQLCR T LFY +RAQAWS+D+AED R Sbjct: 947 IRIKRCQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRS 1006 Query: 1336 LLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALG 1395 LL L RLN LR EQNFADRFLPDDEAAQALGKTCWEALVSP+VQNITSPD +G+S LG Sbjct: 1007 LLHLSSRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLG 1066 Query: 1396 WLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSPEPST-RPFSKNSKGR 1454 WLLDQYLE +E NP SR +F SRVRRL HLLVHVEP P P +T RP +N + Sbjct: 1067 WLLDQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRN-RSH 1125 Query: 1455 DRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSE 1514 D S + LPSS +RN+T+CW +VV++QV+ FL ++WR DFVPRYC+ + LQ + SE Sbjct: 1126 DWSSLATRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSE 1185 Query: 1515 LFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGGLIGGAPGVEMLGQL 1574 LFGPRAAF+LAL++G +GALL+ FL AAH+SEQFAR+IDQQIQG IGGA +E L QL Sbjct: 1186 LFGPRAAFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQL 1245 Query: 1575 QRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQLML 1634 Q+ L+ +++ SGLE+ATTFEH+YQHYMADRLL SSWLEGAVLEQIG CFPNRLPQ ML Sbjct: 1246 QQCLQAVLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQML 1305 Query: 1635 QSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEK------------RLEEEEEE------ 1676 QSLSTS+ELQRQFH++QLQ+LD+ L+ ED E+K + E+EEE Sbjct: 1306 QSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVV 1365 Query: 1677 -----EEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRF 1731 EEEEE ++L+ E P +S+LVLS WPV+ +C+ +PR CLP+ L+R+ Sbjct: 1366 DVAEGEEEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRY 1425 Query: 1732 SSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVE 1791 S+FY++SQ+HP L+ G RRLQWTWLG AELQFG Q LHVSTVQMWLLL N + VSVE Sbjct: 1426 SNFYNKSQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVE 1485 Query: 1792 TLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPG--PQRSGEALWLI 1849 +LL S LS ++L QA+ PLTS GPL LHE +D P GGVL++ + P+ + + LI Sbjct: 1486 SLLAFSGLSADMLNQAIGPLTSSRGPLDLHEQKDIP-GGVLKIRDGSKEPRSRWDIVRLI 1544 Query: 1850 PPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPG 1909 PPQ YL E ++G+ LE++RNLL+CL+VRILKAHG++GLHIDQLVCLVLEAWQKGP PP Sbjct: 1545 PPQTYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPR 1604 Query: 1910 TLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAP 1954 L ++ G AC+STDVLSCILHLLG+G ++R DDRPQ+L YA P Sbjct: 1605 GLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVLSYAVP 1649 Score = 607 bits (1566), Expect = e-173 Identities = 342/637 (53%), Positives = 434/637 (68%), Gaps = 29/637 (4%) Query: 1 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGK--VGVEEG 58 MVGE + VPLGP L AYP+ELIRQR GHDGHPEY IRW +L+ G+ G G + Sbjct: 1 MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC 60 Query: 59 KAEHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEAD 118 KAEHIL+W+S E+YANC +LGE G E AG + G LD+ + EME D Sbjct: 61 KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAG-------EVGALDKSVLEEMETD 113 Query: 119 VQALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNP 178 V++L++RA RQL E A +LHT+HVLSAYASI PLTGVF++ LDLLMHML +P Sbjct: 114 VKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSP 173 Query: 179 EPQIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEE 238 + QIR SAG+M+QAL++HDAG+R +LLSLSQQ+ IE+H+DFDSR LL LFA+ T S E Sbjct: 174 DYQIRWSAGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLS-E 232 Query: 239 HCMAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLN-SSPELGAGDQSSPCATREKSRGQ 297 H M+FEGI LPQ+PG++LFSLVKRYL VTSLLDQLN S+ E GA + S+P RGQ Sbjct: 233 HPMSFEGIQLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAP-EELSGERGQ 291 Query: 298 RELEFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPR 357 ELEFSMA+G LISELV++M W + S++ S R SIFQP ++ S LP P Sbjct: 292 LELEFSMAMGTLISELVQAMRWDQ-ASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPS 350 Query: 358 -RQGWVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPV 416 R+ FR RSEF+S + Y YV+ TLQPGMRVRMLDDYEEISAGDEGEFRQSNNG+PPV Sbjct: 351 FRRSRRFRPRSEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPV 410 Query: 417 QVFWQSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGAT-VLGTAFPSWDWNPMDGL 475 QVFW+STGRTYWVHWHMLEILG EE ED A +GA A+ VLG A P+W W PM L Sbjct: 411 QVFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTEL 470 Query: 476 YPLPYLQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLD-ETLGEKAL 534 Y +PY+ PE + E +LT AEWWELLFFIKKLD + Q + Q L +NLD E L ++ L Sbjct: 471 YAVPYVLPEDEDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEIL 530 Query: 535 GEISVSVEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDP 594 E++V +E+A+ LL L R S L DL+N +Y KYG P + + ++ + + Sbjct: 531 AELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKYG-----PEALAGNQAYPSLLEA 585 Query: 595 EE-----ESKSEASFSEEETESLKAKAEAPKTEAEPT 626 +E +++++A SE ++ K +A+ P +++ T Sbjct: 586 QEDVLLLDAQAQAKDSE---DAAKVEAKEPPSQSPNT 619 >gi|5453557 ariadne homolog 2 [Homo sapiens] Length = 493 Score = 177 bits (449), Expect = 1e-43 Identities = 108/407 (26%), Positives = 181/407 (44%), Gaps = 33/407 (8%) Query: 2000 QEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQ 2059 +E EG + + + + L + VA+ +L + HW ++L Y + LL+ A + + Sbjct: 67 KESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEARVQPNP 126 Query: 2060 AQAVPVR--PDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPI 2117 ++ VP P HC VC+ + ++L SL C H C+SCW ++ + ++ + + +C Sbjct: 127 SKHVPTSHPPHHCAVCMQFVR-KENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMA 185 Query: 2118 ADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGC 2177 DCP + F+ ++ + E+ KY + L R YVES L C I ++ Sbjct: 186 QDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRAR 245 Query: 2178 GTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCP 2237 C++C CF C H P C + +W+ + ++++ + +K CP Sbjct: 246 RVQCNRCNEVFCFKCR-QMYHAPTDCATIRKWLTK------CADDSETANYISAHTKDCP 298 Query: 2238 SCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS-----------AMVSKA 2286 C IEKN GC HM C+KC H FCW CL WK + +YY CS + ++A Sbjct: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQA 358 Query: 2287 ARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPR---------SFTFLNDACQ 2337 K++ Y ER H+++ + R IHE R + +L +A + Sbjct: 359 REALKKYLFYFERWENHNKSLQLEAQTYQR---IHEKIQERVMNNLGTWIDWQYLQNAAK 415 Query: 2338 GLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLE 2384 L + R L Y Y++Y + + E Q LE L +E Sbjct: 416 LLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVE 462 >gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 [Homo sapiens] Length = 557 Score = 149 bits (377), Expect = 3e-35 Identities = 117/453 (25%), Positives = 190/453 (41%), Gaps = 43/453 (9%) Query: 1997 MSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLC 2056 ++ +++ M + +R+V E + + + LL+H +W E+L++ Y + L A Sbjct: 104 LTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHV 163 Query: 2057 VHQAQAVPVRPDHCPVCVSPLGC--------DDDLPSLCCMHYCCKSCWNEYLTTRI-EQ 2107 ++ ++ R + + C + L C H C CW+EYLTT+I E+ Sbjct: 164 INPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEE 223 Query: 2108 NLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCD 2167 + +CP C + +++ +V KY+ + +VE L WC P C Sbjct: 224 GMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPD-CH 282 Query: 2168 RILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWV---DDGGYYDGMSVEAQ 2224 ++ Q KCG CFNC H P C + +W+ DD +++ Sbjct: 283 HVVKVQYPDAKPVRCKCGRQFCFNCG-ENWHDPVKCKWLKKWIKKCDD---------DSE 332 Query: 2225 SKHLAKLISKRCPSCQAPIEKNEGCLHMTCAK--CNHGFCWRCLKSWKPNHKDYYNCSAM 2282 + + +K CP C IEK+ GC HM C C FCW CL W+P+ +YNC+ Sbjct: 333 TSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRY 392 Query: 2283 ---VSKAAR--QEK------RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFT- 2330 +KAAR QE+ R+ Y R H Q+ F L +V E + + Sbjct: 393 NEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSW 452 Query: 2331 ----FLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEET 2386 FL A L Q R L Y V++FY + + E +LE T L LE Sbjct: 453 IEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERD 512 Query: 2387 LLR--CRDLASSLRLLRADCLSTGMELLRRIQE 2417 + + +D+ ++ C S LL+ + E Sbjct: 513 ISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHE 545 >gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sapiens] Length = 1089 Score = 136 bits (342), Expect = 3e-31 Identities = 117/497 (23%), Positives = 200/497 (40%), Gaps = 96/497 (19%) Query: 1997 MSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLC 2056 + PQ++ L + + + L A+ LL W E+LL+++ +PE +G+ Sbjct: 228 LRPQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQ 287 Query: 2057 V--------------------HQAQAVPVRPDH------------CPVCVSPLGCDDDLP 2084 + ++ PD C +C+ + +D Sbjct: 288 MPTPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPV 347 Query: 2085 SLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEK 2144 + C H C+ CW +L +I++ N CP DC I ++VS E+ +Y + Sbjct: 348 DMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVVSK-EMDKRYLQ 406 Query: 2145 ALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTT----------------CSKCGWAS 2188 ++ +VE+ + WC P GCDR + G T+ C K G Sbjct: 407 FDIKAFVENNPAIKWCPTP-GCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGK-GHLF 464 Query: 2189 CFNCSFPEAHYPASCGHMSQW---VDDGGYYDGMSVEAQSKHLAKLI-----SKRCPSCQ 2240 C+ C EAH P C W + + + + V + A + SK C +C+ Sbjct: 465 CWEC-LGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCK 523 Query: 2241 APIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKD---YYNCS-------------AMVS 2284 +PI+KNEGC HM CAKC + FCW CL+ WK + YY C+ M Sbjct: 524 SPIQKNEGCNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTV 583 Query: 2285 KAARQEKRFQDYNERCTFHHQAR--EFAVNLRNRV------------SAIHEVPPP-RSF 2329 +A ++ KRFQ+ + ++ + + E + L R+ A+ E Sbjct: 584 EAEKKHKRFQELDRFMHYYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDT 643 Query: 2330 TFLNDACQGLEQARKVLAYACVYSFYSQ-DAEYMDVVEQQTENLELHTNALQILLEETLL 2388 TF+ DA L + R++L + Y F+ + + ++ E +LE+ T L + L Sbjct: 644 TFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYL 703 Query: 2389 RCRDLASSLRLLRADCL 2405 R ++++A CL Sbjct: 704 R----TPRHKIIKAACL 716 >gi|126032348 hect domain and RLD 2 [Homo sapiens] Length = 4834 Score = 95.1 bits (235), Expect = 8e-19 Identities = 52/127 (40%), Positives = 83/127 (65%), Gaps = 2/127 (1%) Query: 1171 EKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYM 1230 + + VSS+ ++AS+L D + + W+S+GS G H+I L + VLV +L ++V DSSYM Sbjct: 2787 KSLNVSSSVNQASRLIDGS-EPCWQSSGSQGKHWIRLEIFPDVLVHRLKMIVDPADSSYM 2845 Query: 1231 PARVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRV 1290 P+ VVV GG+S + + EL T+N+ PS + V LL + + I+I IK+C+ GID ++ Sbjct: 2846 PSLVVVSGGNSLNNL-IELKTININPSDTTVPLLNDCTEYHRYIEIAIKQCRSSGIDCKI 2904 Query: 1291 RGVEVLG 1297 G+ +LG Sbjct: 2905 HGLILLG 2911 Score = 59.7 bits (143), Expect = 4e-08 Identities = 36/113 (31%), Positives = 56/113 (49%), Gaps = 11/113 (9%) Query: 363 FRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGE-FRQSNNGIPP--VQVF 419 +++R++F S Y YV++ +Q GM VR YEE+ GD G+ + +G+ VQ Sbjct: 2551 YKKRADFLSNDDYAVYVRENIQVGMMVRCCRAYEEVCEGDVGKVIKLDRDGLHDLNVQCD 2610 Query: 420 WQSTGRTYWVHWHMLEILG---PEEATEDKASAAVEKGAGATVLGTAFPSWDW 469 WQ G TYWV + +E++G P ++ K V A T P + W Sbjct: 2611 WQQKGGTYWVRYIHVELIGYPPPSSSSHIKIGDKVRVKASVTT-----PKYKW 2658 >gi|157738609 HECT domain containing 3 [Homo sapiens] Length = 861 Score = 93.6 bits (231), Expect = 2e-18 Identities = 52/128 (40%), Positives = 80/128 (62%), Gaps = 5/128 (3%) Query: 1171 EKVEVSS--NPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSS 1228 E ++VSS S LTD N TYWES+GS H++ L M +G +V++L L V + D + Sbjct: 245 ESIDVSSYTEEFNVSCLTDSNADTYWESDGSQCQHWVRLTMKKGTIVKKLLLTVDTTDDN 304 Query: 1229 YMPARVVVFGGDSTSCIGTELNTVNVMPS-ASRVILLENLNRFWPIIQIRIKRCQQGGID 1287 +MP RVVV+GG+ + +L+ V++ + V +LE++ PII+IRI C+ GID Sbjct: 305 FMPKRVVVYGGEGDNL--KKLSDVSIDETLIGDVCVLEDMTVHLPIIEIRIVECRDDGID 362 Query: 1288 TRVRGVEV 1295 R+RGV++ Sbjct: 363 VRLRGVKI 370 >gi|73747881 zinc finger, ZZ type with EF hand domain 1 [Homo sapiens] Length = 2961 Score = 92.8 bits (229), Expect = 4e-18 Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 2/131 (1%) Query: 1168 KCWEKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDS 1227 KC+ +E SSN K+T+ +YW+S+GS SH+I L M V++R L++ VA+ D Sbjct: 251 KCYAYIETSSNSADIDKMTNGETSSYWQSDGSACSHWIRLKMKPDVVLRHLSIAVAATDQ 310 Query: 1228 SYMPARVVVFGGDSTSCIGTELNTVNVMPSAS-RVILLENLNRFWPIIQIRIKRCQQGGI 1286 SYMP +V V G + S + E+ V++ + + V LLEN N +QI IKRC G Sbjct: 311 SYMPQQVTVAVGRNASDL-QEVRDVHIPSNVTGYVTLLENANVSQLYVQINIKRCLSDGC 369 Query: 1287 DTRVRGVEVLG 1297 DTR+ G+ +G Sbjct: 370 DTRIHGLRAVG 380 >gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 90.5 bits (223), Expect = 2e-17 Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 C +C + + L C H CK+C +Y +I V CP CP+ T + Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279 Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188 + +V + E+ ++Y++ LL+ ++ +++ +C P+ C ++ Q GC CS C +A Sbjct: 280 KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 336 Query: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227 C C H + C ++ + D Y E +SK Sbjct: 337 CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395 Query: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268 + SK CP C PIEK +GC MTC C FCW C+ S Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 436 >gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 90.5 bits (223), Expect = 2e-17 Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 C +C + + L C H CK+C +Y +I V CP CP+ T + Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279 Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188 + +V + E+ ++Y++ LL+ ++ +++ +C P+ C ++ Q GC CS C +A Sbjct: 280 KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 336 Query: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227 C C H + C ++ + D Y E +SK Sbjct: 337 CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395 Query: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268 + SK CP C PIEK +GC MTC C FCW C+ S Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 436 >gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 90.5 bits (223), Expect = 2e-17 Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 C +C + + L C H CK+C +Y +I V CP CP+ T + Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279 Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188 + +V + E+ ++Y++ LL+ ++ +++ +C P+ C ++ Q GC CS C +A Sbjct: 280 KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 336 Query: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227 C C H + C ++ + D Y E +SK Sbjct: 337 CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395 Query: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268 + SK CP C PIEK +GC MTC C FCW C+ S Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 436 >gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] Length = 348 Score = 90.5 bits (223), Expect = 2e-17 Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 C +C + + L C H CK+C +Y +I V CP CP+ T + Sbjct: 94 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153 Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188 + +V + E+ ++Y++ LL+ ++ +++ +C P+ C ++ Q GC CS C +A Sbjct: 154 KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 210 Query: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227 C C H + C ++ + D Y E +SK Sbjct: 211 CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 269 Query: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268 + SK CP C PIEK +GC MTC C FCW C+ S Sbjct: 270 WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 310 >gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 90.5 bits (223), Expect = 2e-17 Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 C +C + + L C H CK+C +Y +I V CP CP+ T + Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279 Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188 + +V + E+ ++Y++ LL+ ++ +++ +C P+ C ++ Q GC CS C +A Sbjct: 280 KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 336 Query: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227 C C H + C ++ + D Y E +SK Sbjct: 337 CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 395 Query: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268 + SK CP C PIEK +GC MTC C FCW C+ S Sbjct: 396 WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 436 >gi|188219579 ring finger protein 19B isoform b [Homo sapiens] Length = 587 Score = 89.0 bits (219), Expect = 5e-17 Identities = 63/217 (29%), Positives = 94/217 (43%), Gaps = 23/217 (10%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 CP+C+ L + L C H C+ C YL I ++ V +CP +C + I Sbjct: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCP--ECSERLNPHDI 175 Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASC 2189 R +++ P ++ KYE+ +LR Y+ S + WC P C + G C+ C +C Sbjct: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPD-CGYAVIAYG------CASCPKLTC 228 Query: 2190 FN--CSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLIS---------KRCPS 2238 C ++ H +Q D ++ ++KH + L K CP Sbjct: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPR 288 Query: 2239 CQAPIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273 C A I K N+G C HMTCA C FCW C+K H Sbjct: 289 CSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 325 >gi|188219577 ring finger protein 19B isoform a [Homo sapiens] Length = 732 Score = 88.6 bits (218), Expect = 7e-17 Identities = 63/218 (28%), Positives = 94/218 (43%), Gaps = 24/218 (11%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 CP+C+ L + L C H C+ C YL I ++ V +CP +C + I Sbjct: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCP--ECSERLNPHDI 175 Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASC 2189 R +++ P ++ KYE+ +LR Y+ S + WC P C + G C+ C +C Sbjct: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPD-CGYAVIAYG------CASCPKLTC 228 Query: 2190 FN--CSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLIS----------KRCP 2237 C ++ H +Q D ++ ++KH + L K CP Sbjct: 229 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCP 288 Query: 2238 SCQAPIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273 C A I K N+G C HMTCA C FCW C+K H Sbjct: 289 RCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 326 >gi|35493801 ring finger protein 19 [Homo sapiens] Length = 838 Score = 82.8 bits (203), Expect = 4e-15 Identities = 63/215 (29%), Positives = 93/215 (43%), Gaps = 17/215 (7%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 CP+C+ D + C H C C +YL I ++ V N +CP +C + I Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRV-NISCP--ECTERFNPHDI 188 Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT----TCSK-- 2183 R I+S ++ KYE+ +LR ++ + + WC P ++ GC + TC + Sbjct: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIA---FGCASCPKLTCGREG 245 Query: 2184 CGWASCFNCS---FPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQ 2240 CG C++C P A+ +Q + +Q A K CP C Sbjct: 246 CGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCA 305 Query: 2241 APIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273 A I K N+G C HMTCA C FCW C+K H Sbjct: 306 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 340 >gi|35493782 ring finger protein 19 [Homo sapiens] Length = 838 Score = 82.8 bits (203), Expect = 4e-15 Identities = 63/215 (29%), Positives = 93/215 (43%), Gaps = 17/215 (7%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 CP+C+ D + C H C C +YL I ++ V N +CP +C + I Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRV-NISCP--ECTERFNPHDI 188 Query: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT----TCSK-- 2183 R I+S ++ KYE+ +LR ++ + + WC P ++ GC + TC + Sbjct: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIA---FGCASCPKLTCGREG 245 Query: 2184 CGWASCFNCS---FPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQ 2240 CG C++C P A+ +Q + +Q A K CP C Sbjct: 246 CGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCA 305 Query: 2241 APIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273 A I K N+G C HMTCA C FCW C+K H Sbjct: 306 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 340 >gi|38045938 ring finger protein 144 [Homo sapiens] Length = 292 Score = 76.6 bits (187), Expect = 3e-13 Identities = 55/205 (26%), Positives = 78/205 (38%), Gaps = 13/205 (6%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQP--TGA 2127 C +C+ + C C C +Y+ I++ L +CP A CP Q Sbjct: 20 CKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQEN 79 Query: 2128 FIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTT----CSK 2183 I +V++ E++ +Y+K V TWC C + Q +G T C Sbjct: 80 EIECMVAA-EIMQRYKKLQFEREVLFDPCRTWCP-ASTCQAVCQLQDVGLQTPQPVQCKA 137 Query: 2184 CGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPI 2243 C C C H C + G + A KRCP C+ I Sbjct: 138 CRMEFCSTCK-ASWHPGQGCPETMPIT----FLPGETSAAFKMEEDDAPIKRCPKCKVYI 192 Query: 2244 EKNEGCLHMTCAKCNHGFCWRCLKS 2268 E++EGC M C C H FCW CL+S Sbjct: 193 ERDEGCAQMMCKNCKHAFCWYCLES 217 >gi|169790973 parkin isoform 3 [Homo sapiens] Length = 316 Score = 67.0 bits (162), Expect = 2e-10 Identities = 54/207 (26%), Positives = 80/207 (38%), Gaps = 37/207 (17%) Query: 2090 HYCCKSCWNEYLTTRI-------EQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKY 2142 H C C++ Y TR+ + L + C +A CP + E ++Y Sbjct: 108 HVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPC-VAGCPNSLIKELHHFRILGEEQYNRY 166 Query: 2143 EKALLRGYVESCSNLTWCTNPQGCD----------RILCRQGLGCGTTCSKCGWASCFNC 2192 ++ V + C P GC ++ C G G G CG+A C C Sbjct: 167 QQYGAEECVLQMGGVL-CPRP-GCGAGLLPEPDQRKVTCEGGNGLG-----CGFAFCREC 219 Query: 2193 SFPEAHYPASCGHMSQ--------WVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIE 2244 EA++ C + + + D + EA SK K +K CP C P+E Sbjct: 220 K--EAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVE 277 Query: 2245 KNEGCLHMTC--AKCNHGFCWRCLKSW 2269 KN GC+HM C +C +CW C W Sbjct: 278 KNGGCMHMKCPQPQCRLEWCWNCGCEW 304 >gi|169790971 parkin isoform 2 [Homo sapiens] Length = 437 Score = 67.0 bits (162), Expect = 2e-10 Identities = 54/207 (26%), Positives = 80/207 (38%), Gaps = 37/207 (17%) Query: 2090 HYCCKSCWNEYLTTRI-------EQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKY 2142 H C C++ Y TR+ + L + C +A CP + E ++Y Sbjct: 229 HVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPC-VAGCPNSLIKELHHFRILGEEQYNRY 287 Query: 2143 EKALLRGYVESCSNLTWCTNPQGCD----------RILCRQGLGCGTTCSKCGWASCFNC 2192 ++ V + C P GC ++ C G G G CG+A C C Sbjct: 288 QQYGAEECVLQMGGVL-CPRP-GCGAGLLPEPDQRKVTCEGGNGLG-----CGFAFCREC 340 Query: 2193 SFPEAHYPASCGHMSQ--------WVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIE 2244 EA++ C + + + D + EA SK K +K CP C P+E Sbjct: 341 K--EAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVE 398 Query: 2245 KNEGCLHMTC--AKCNHGFCWRCLKSW 2269 KN GC+HM C +C +CW C W Sbjct: 399 KNGGCMHMKCPQPQCRLEWCWNCGCEW 425 >gi|169790969 parkin isoform 1 [Homo sapiens] Length = 465 Score = 67.0 bits (162), Expect = 2e-10 Identities = 54/207 (26%), Positives = 80/207 (38%), Gaps = 37/207 (17%) Query: 2090 HYCCKSCWNEYLTTRI-------EQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKY 2142 H C C++ Y TR+ + L + C +A CP + E ++Y Sbjct: 257 HVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPC-VAGCPNSLIKELHHFRILGEEQYNRY 315 Query: 2143 EKALLRGYVESCSNLTWCTNPQGCD----------RILCRQGLGCGTTCSKCGWASCFNC 2192 ++ V + C P GC ++ C G G G CG+A C C Sbjct: 316 QQYGAEECVLQMGGVL-CPRP-GCGAGLLPEPDQRKVTCEGGNGLG-----CGFAFCREC 368 Query: 2193 SFPEAHYPASCGHMSQ--------WVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIE 2244 EA++ C + + + D + EA SK K +K CP C P+E Sbjct: 369 K--EAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVE 426 Query: 2245 KNEGCLHMTC--AKCNHGFCWRCLKSW 2269 KN GC+HM C +C +CW C W Sbjct: 427 KNGGCMHMKCPQPQCRLEWCWNCGCEW 453 >gi|50284696 IBR domain containing 2 [Homo sapiens] Length = 303 Score = 65.5 bits (158), Expect = 6e-10 Identities = 52/211 (24%), Positives = 76/211 (36%), Gaps = 27/211 (12%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYC----CKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPT 2125 C +C+ C+ L + + C C +C +Y+ I + TCP C T Sbjct: 30 CKLCL----CEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGT 85 Query: 2126 --GAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSK 2183 A I +V + Y++ V TWC C + C S Sbjct: 86 LQEAEIACLVPVDQ-FQLYQRLKFEREVHLDPYRTWCPVAD-CQTV-------CPVASSD 136 Query: 2184 CGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLIS------KRCP 2237 G C P H W + D + ++H A + K+CP Sbjct: 137 PGQPVLVEC--PSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCP 194 Query: 2238 SCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268 C+ IE+NEGC M C C H FCW CL++ Sbjct: 195 VCRVYIERNEGCAQMMCKNCKHTFCWYCLQN 225 >gi|109150431 ring finger protein 31 [Homo sapiens] Length = 1072 Score = 58.5 bits (140), Expect = 8e-08 Identities = 47/223 (21%), Positives = 78/223 (34%), Gaps = 29/223 (13%) Query: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 C VC L + C C C+ ++ T +++ + + CP P + Sbjct: 699 CAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQL 758 Query: 2130 RAIVSS----------PEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT 2179 + S+ P+ + + K L G + WC C + Sbjct: 759 LSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQ---CSFGFIYEREQLEA 815 Query: 2180 TCSKCGWASCFNCS--FPEAHYPASCGHMSQW--VDDGGYYDGMSVEAQSKHLAKLISKR 2235 TC +C C C + E H SC W ++D Y Q++ LA + + Sbjct: 816 TCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEY--------QAQGLAMYLQEN 867 Query: 2236 ---CPSCQAPIE-KNEGCLHMTCAKCNHGFCWRCLKSWKPNHK 2274 CP C+ GC+H C +C H FC C ++ +K Sbjct: 868 GIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNK 910 Score = 35.0 bits (79), Expect = 0.93 Identities = 27/125 (21%), Positives = 45/125 (36%), Gaps = 16/125 (12%) Query: 2236 CPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQD 2295 C C L TC +C+ FC RC + W+ H+ R + FQ+ Sbjct: 799 CAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHR------------GRSCEDFQN 846 Query: 2296 YNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE--QARKVLAYACVYS 2353 + +QA+ A+ L+ + I S+ C Q R C + Sbjct: 847 WKRMNDPEYQAQGLAMYLQE--NGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNA 904 Query: 2354 FYSQD 2358 FY+++ Sbjct: 905 FYAKN 909 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 55.8 bits (133), Expect = 5e-07 Identities = 28/73 (38%), Positives = 43/73 (58%) Query: 2445 KGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFF 2504 +GPN S+ S E+EE++E+DEDD E +++E DE D+ D SE+ ++ Sbjct: 623 RGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 682 Query: 2505 FGDEEEDEDEAYD 2517 GDE E++DE D Sbjct: 683 DGDENEEDDEDED 695 Score = 36.6 bits (83), Expect = 0.32 Identities = 20/71 (28%), Positives = 35/71 (49%) Query: 2443 EAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQET 2502 ++K + + E EEEE+D+ D E D + +++S DE+E D++ Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694 Query: 2503 FFFGDEEEDED 2513 D++EDED Sbjct: 695 DDDEDDDEDED 705 Score = 34.7 bits (78), Expect = 1.2 Identities = 15/39 (38%), Positives = 26/39 (66%) Query: 2451 GSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDS 2489 G ++SS E+E+ +E++EDD E ++ DE+ DN+S Sbjct: 670 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708 Score = 32.0 bits (71), Expect = 7.9 Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 4/48 (8%) Query: 2452 SQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLD 2499 S+ ++ G E EE++ED++DD + D+ DE+ +++ S S + D Sbjct: 677 SEDESEDGDENEEDDEDEDDD----EDDDEDEDNESEGSSSSSSSSGD 720 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 55.8 bits (133), Expect = 5e-07 Identities = 28/73 (38%), Positives = 43/73 (58%) Query: 2445 KGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFF 2504 +GPN S+ S E+EE++E+DEDD E +++E DE D+ D SE+ ++ Sbjct: 623 RGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 682 Query: 2505 FGDEEEDEDEAYD 2517 GDE E++DE D Sbjct: 683 DGDENEEDDEDED 695 Score = 36.6 bits (83), Expect = 0.32 Identities = 20/71 (28%), Positives = 35/71 (49%) Query: 2443 EAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQET 2502 ++K + + E EEEE+D+ D E D + +++S DE+E D++ Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694 Query: 2503 FFFGDEEEDED 2513 D++EDED Sbjct: 695 DDDEDDDEDED 705 Score = 34.7 bits (78), Expect = 1.2 Identities = 15/39 (38%), Positives = 26/39 (66%) Query: 2451 GSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDS 2489 G ++SS E+E+ +E++EDD E ++ DE+ DN+S Sbjct: 670 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708 Score = 32.0 bits (71), Expect = 7.9 Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 4/48 (8%) Query: 2452 SQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLD 2499 S+ ++ G E EE++ED++DD + D+ DE+ +++ S S + D Sbjct: 677 SEDESEDGDENEEDDEDEDDD----EDDDEDEDNESEGSSSSSSSSGD 720 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 55.8 bits (133), Expect = 5e-07 Identities = 28/73 (38%), Positives = 43/73 (58%) Query: 2445 KGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFF 2504 +GPN S+ S E+EE++E+DEDD E +++E DE D+ D SE+ ++ Sbjct: 660 RGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 719 Query: 2505 FGDEEEDEDEAYD 2517 GDE E++DE D Sbjct: 720 DGDENEEDDEDED 732 Score = 36.6 bits (83), Expect = 0.32 Identities = 20/71 (28%), Positives = 35/71 (49%) Query: 2443 EAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQET 2502 ++K + + E EEEE+D+ D E D + +++S DE+E D++ Sbjct: 672 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731 Query: 2503 FFFGDEEEDED 2513 D++EDED Sbjct: 732 DDDEDDDEDED 742 Score = 34.7 bits (78), Expect = 1.2 Identities = 15/39 (38%), Positives = 26/39 (66%) Query: 2451 GSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDS 2489 G ++SS E+E+ +E++EDD E ++ DE+ DN+S Sbjct: 707 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 745 Score = 32.0 bits (71), Expect = 7.9 Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 4/48 (8%) Query: 2452 SQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLD 2499 S+ ++ G E EE++ED++DD + D+ DE+ +++ S S + D Sbjct: 714 SEDESEDGDENEEDDEDEDDD----EDDDEDEDNESEGSSSSSSSSGD 757 >gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 isoform 1 [Homo sapiens] Length = 468 Score = 55.5 bits (132), Expect = 7e-07 Identities = 46/211 (21%), Positives = 77/211 (36%), Gaps = 29/211 (13%) Query: 2067 PDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTG 2126 P CPVC S L + + C+H C+ C L I + +CP D +G Sbjct: 237 PAECPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRNSQEAEVSCPFIDNTYSCSG 292 Query: 2127 AFIRAIVSSPEVISKYEKALLRGY--VESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKC 2184 + + + Y++ L G E+ S ++ C + TC C Sbjct: 293 KLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVC 352 Query: 2185 GWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISK---------- 2234 +C C H +C Y + +++ AQ+ A+ ++ Sbjct: 353 FHVNCLLCK--AIHEQMNCKE---------YQEDLALRAQNDVAARQTTEMLKVMLQQGE 401 Query: 2235 --RCPSCQAPIEKNEGCLHMTCAKCNHGFCW 2263 RCP CQ ++K +GC + C C+ CW Sbjct: 402 AMRCPQCQIVVQKKDGCDWIRCTVCHTEICW 432 >gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 isoform 2 [Homo sapiens] Length = 510 Score = 55.5 bits (132), Expect = 7e-07 Identities = 46/211 (21%), Positives = 77/211 (36%), Gaps = 29/211 (13%) Query: 2067 PDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTG 2126 P CPVC S L + + C+H C+ C L I + +CP D +G Sbjct: 279 PAECPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRNSQEAEVSCPFIDNTYSCSG 334 Query: 2127 AFIRAIVSSPEVISKYEKALLRGY--VESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKC 2184 + + + Y++ L G E+ S ++ C + TC C Sbjct: 335 KLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVC 394 Query: 2185 GWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISK---------- 2234 +C C H +C Y + +++ AQ+ A+ ++ Sbjct: 395 FHVNCLLCK--AIHEQMNCKE---------YQEDLALRAQNDVAARQTTEMLKVMLQQGE 443 Query: 2235 --RCPSCQAPIEKNEGCLHMTCAKCNHGFCW 2263 RCP CQ ++K +GC + C C+ CW Sbjct: 444 AMRCPQCQIVVQKKDGCDWIRCTVCHTEICW 474 >gi|22749145 ring finger protein 217 [Homo sapiens] Length = 275 Score = 54.7 bits (130), Expect = 1e-06 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 7/85 (8%) Query: 2181 CSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQ 2240 C C + CF C P H +C + D + +E ++ +++CP C+ Sbjct: 83 CPTCQFVWCFKCHSPW-HEGVNCKEYKKG-DKLLRHWASEIEHGQRN-----AQKCPKCK 135 Query: 2241 APIEKNEGCLHMTCAKCNHGFCWRC 2265 I++ EGC HMTC++CN FC+RC Sbjct: 136 IHIQRTEGCDHMTCSQCNTNFCYRC 160 >gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein [Homo sapiens] Length = 593 Score = 48.5 bits (114), Expect = 8e-05 Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 11/80 (13%) Query: 2437 PSVEAWEAKGPNMPGSQPQASSGPEAEEEEE--DDEDDVPEWQQDEFDEELDNDSFSYDE 2494 P E +A PGS + GP E E+ DED P+W+++E +E+L D +E Sbjct: 86 PGSEEEDAAREGTPGSPGRGREGPGEEHFEDMASDEDMKPKWEEEEMEEDLGED----EE 141 Query: 2495 SENLDQETFFFGDEEEDEDE 2514 E D E DEEE+EDE Sbjct: 142 EEEEDYE-----DEEEEEDE 156 Score = 32.7 bits (73), Expect = 4.6 Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 5/48 (10%) Query: 1661 EQEDEEEKRLEEEEEEEE----EEEAEKELFIEDPSPA-ISILVLSPR 1703 E+E+ EE E+EEEEEE EEE E E + P PA + L PR Sbjct: 128 EEEEMEEDLGEDEEEEEEDYEDEEEEEDEEGLGPPGPASLGTTALFPR 175 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.134 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 106,298,482 Number of Sequences: 37866 Number of extensions: 5452492 Number of successful extensions: 55283 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 309 Number of HSP's successfully gapped in prelim test: 191 Number of HSP's that attempted gapping in prelim test: 39257 Number of HSP's gapped (non-prelim): 11232 length of query: 2517 length of database: 18,247,518 effective HSP length: 119 effective length of query: 2398 effective length of database: 13,741,464 effective search space: 32952030672 effective search space used: 32952030672 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.