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Search of human proteins with 24233517
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24233517 IKK interacting protein isoform 1 [Homo sapiens]
(377 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24233517 IKK interacting protein isoform 1 [Homo sapiens] 736 0.0
gi|42491362 IKK interacting protein isoform 2 [Homo sapiens] 238 7e-63
gi|42476085 IKK interacting protein isoform 3.1 [Homo sapiens] 123 2e-28
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 67 3e-11
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 66 4e-11
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 66 4e-11
gi|118498362 kinectin 1 isoform b [Homo sapiens] 64 3e-10
gi|118498356 kinectin 1 isoform a [Homo sapiens] 64 3e-10
gi|118498368 kinectin 1 isoform c [Homo sapiens] 64 3e-10
gi|33620775 kinectin 1 isoform a [Homo sapiens] 64 3e-10
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 62 8e-10
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 61 2e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 61 2e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 61 2e-09
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 61 2e-09
gi|71061468 centromere protein E [Homo sapiens] 60 3e-09
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 60 4e-09
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 59 9e-09
gi|33188445 microfilament and actin filament cross-linker protei... 58 1e-08
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 57 2e-08
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 57 2e-08
gi|156104908 myosin heavy chain 6 [Homo sapiens] 57 2e-08
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 57 2e-08
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 57 3e-08
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 57 3e-08
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 57 3e-08
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 57 3e-08
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 56 5e-08
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 56 6e-08
gi|38044112 restin isoform b [Homo sapiens] 56 6e-08
>gi|24233517 IKK interacting protein isoform 1 [Homo sapiens]
Length = 377
Score = 736 bits (1900), Expect = 0.0
Identities = 377/377 (100%), Positives = 377/377 (100%)
Query: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW 60
MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW
Sbjct: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW 60
Query: 61 FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQF 120
FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQF
Sbjct: 61 FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQF 120
Query: 121 EQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
EQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI
Sbjct: 121 EQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
Query: 181 HSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK 240
HSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK
Sbjct: 181 HSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK 240
Query: 241 LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDL 300
LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDL
Sbjct: 241 LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDL 300
Query: 301 TMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEK 360
TMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEK
Sbjct: 301 TMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEK 360
Query: 361 GTLKEYNIENKGIGGDF 377
GTLKEYNIENKGIGGDF
Sbjct: 361 GTLKEYNIENKGIGGDF 377
>gi|42491362 IKK interacting protein isoform 2 [Homo sapiens]
Length = 350
Score = 238 bits (607), Expect = 7e-63
Identities = 136/353 (38%), Positives = 216/353 (61%), Gaps = 15/353 (4%)
Query: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW 60
MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW
Sbjct: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW 60
Query: 61 FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSL--MT 118
FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEK + +E+I+++ S + +
Sbjct: 61 FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLK 120
Query: 119 QFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAK 178
+ ++E++ ++ + I +++L + +L++ + +++ + K++ +
Sbjct: 121 RLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIR 180
Query: 179 HIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAI 238
I VT + S ++ L +++ +E +T++NI + + + + +++ I
Sbjct: 181 RISGLVT-DVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRI 239
Query: 239 EKLEE---EQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEK 295
+++ E + F + D L KV + T ++ +++ + +D E
Sbjct: 240 NSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYN---LKKDFSRLEP 296
Query: 296 KMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKV 348
+ DLT+++ + D+L+ EI + + + +++ +Q E+ +K+++
Sbjct: 297 LVNDLTLRIGRLVTDLLQREKEIAFLSEKI------SNLTIVQAEIKDIKDEI 343
>gi|42476085 IKK interacting protein isoform 3.1 [Homo sapiens]
Length = 70
Score = 123 bits (309), Expect = 2e-28
Identities = 59/59 (100%), Positives = 59/59 (100%)
Query: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA 59
MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA
Sbjct: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA 59
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 67.0 bits (162), Expect = 3e-11
Identities = 70/301 (23%), Positives = 145/301 (48%), Gaps = 31/301 (10%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN 126
EK EN+ L ++ET + Q + K+ L E+L++ + EA + +T +QE
Sbjct: 859 EKQLAAENR--LTEMETLQSQLMAEKLQL-QEQLQAETELCAEAEELRARLTAKKQE--- 912
Query: 127 LQDIMHDIQ---NNEEVLTQRMQSLNEKFQNITDFWKRSLEE-----MNINTDIFKSEAK 178
L++I HD++ EE Q +Q+ +K Q + LEE + + +EAK
Sbjct: 913 LEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAK 972
Query: 179 HI---HSQVTVQINSAE--QEIKLLTERLKDL------EDSTLRNIRTVKRQEEEDLLRV 227
Q+ ++ + + +E KLL +R+ + E+ +++ +K + E + +
Sbjct: 973 LKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDL 1032
Query: 228 EEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVL-RV 286
EE+L + K ++LE+ + L DL++++++ + ++ E K L E + + L RV
Sbjct: 1033 EERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARV 1092
Query: 287 SQDLIETE---KKMEDLTMQMFNMEDDM--LKAVSEIMEMQKTLEGIQYDNSILKMQNEL 341
++ + KK+ +L Q+ +++D+ +A E QK G + + ++++ L
Sbjct: 1093 EEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTL 1152
Query: 342 D 342
D
Sbjct: 1153 D 1153
Score = 57.0 bits (136), Expect = 3e-08
Identities = 64/310 (20%), Positives = 133/310 (42%), Gaps = 33/310 (10%)
Query: 70 AKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSM-SLMTQFEQEVSNLQ 128
A+VE + + + ++L+S+IS + E LES + +A L + E + L+
Sbjct: 1090 ARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELE 1149
Query: 129 DIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQI 188
D + +E+ ++R Q +N K++LEE + E + HSQ ++
Sbjct: 1150 DTLDSTAAQQELRSKREQEVN--------ILKKTLEEEAKTHEAQIQEMRQKHSQAVEEL 1201
Query: 189 NSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHAL 248
++ K + L+ + TL N R E + LL+ + K +E +E
Sbjct: 1202 AEQLEQTKRVKANLEKAK-QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK 1260
Query: 249 FARDEDLTNKLSDYEPKVEECKTHLPTIE-----------------SAIHSVLRVSQDLI 291
F E + +L+D KV + + L + SA+ S L+ +Q+L+
Sbjct: 1261 FNEGERVRTELAD---KVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELL 1317
Query: 292 ETEKKME-DLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHD 350
+ E + + L+ ++ +ED+ ++ E ++ + + I + ++ +K+K+ D
Sbjct: 1318 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNL--EKQIATLHAQVADMKKKMED 1375
Query: 351 FIAYSSTGEK 360
+ T E+
Sbjct: 1376 SVGCLETAEE 1385
Score = 46.6 bits (109), Expect = 4e-05
Identities = 36/192 (18%), Positives = 97/192 (50%), Gaps = 11/192 (5%)
Query: 186 VQINSAEQEIKLLTERLKDLED------STLRNIRTVKRQEEEDLLRVEEQLGSDTKAIE 239
+Q++ E+E+ E L + + + L + T++ Q + L+++EQL ++T+
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCA 897
Query: 240 KLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMED 299
+ EE + L A+ ++L D E +VEE + +++ ++ Q++ E E+++E+
Sbjct: 898 EAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQA---EKKKMQQNIQELEEQLEE 954
Query: 300 LTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGE 359
++ + + +++ ++++ E I ++ K+ E +L++++ +F + E
Sbjct: 955 EESARQKLQLEKVTTEAKLKKLEE--EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE 1012
Query: 360 KGTLKEYNIENK 371
+ + ++NK
Sbjct: 1013 EKSKSLAKLKNK 1024
Score = 43.9 bits (102), Expect = 2e-04
Identities = 51/272 (18%), Positives = 117/272 (43%), Gaps = 27/272 (9%)
Query: 65 QSEKFAKVENQYQLLKLETNE--------FQQLQSK----ISLISEKLESTESILQEATS 112
Q E +K E + +LK E Q+++ K + ++E+LE T+ +
Sbjct: 1158 QQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEK 1217
Query: 113 SMSLMTQFEQEVSNLQDIM----HDIQNNEEVLTQRMQSLNEKFQN--------ITDFWK 160
+ + E++N ++ D ++ + + ++Q L KF K
Sbjct: 1218 AKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTK 1277
Query: 161 RSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQE 220
+E N+ + +S++K S++T ++ E +++ E L++ E+ ++ T +Q
Sbjct: 1278 LQVELDNVTGLLSQSDSKS--SKLTKDFSALESQLQDTQELLQE-ENRQKLSLSTKLKQV 1334
Query: 221 EEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAI 280
E++ EQL + +A LE++ L A+ D+ K+ D +E + ++ +
Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDL 1394
Query: 281 HSVLRVSQDLIETEKKMEDLTMQMFNMEDDML 312
+ + ++ + K+E ++ DD+L
Sbjct: 1395 EGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Score = 42.7 bits (99), Expect = 5e-04
Identities = 47/251 (18%), Positives = 104/251 (41%), Gaps = 38/251 (15%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLIS----EKLESTESILQEATSS-------MSLMTQFE 121
EN+ +L +E E QLQ +++ + + + + E +S + + E
Sbjct: 1670 ENEKKLKSMEA-EMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLE 1728
Query: 122 QEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIH 181
++ L++ + + Q N E++ R++ N L+ INTD+ E H
Sbjct: 1729 ARIAQLEEELEEEQGNTELINDRLKKAN-------------LQIDQINTDL-NLERSHAQ 1774
Query: 182 SQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDT------ 235
+ E++ K L +L+++E + + E + ++EEQL ++T
Sbjct: 1775 KNENAR-QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAA 1833
Query: 236 -KAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLP----TIESAIHSVLRVSQDL 290
K + + E++ + + +D Y+ + ++ T L +E A R +
Sbjct: 1834 CKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASR 1893
Query: 291 IETEKKMEDLT 301
+ ++++ED T
Sbjct: 1894 RKLQRELEDAT 1904
Score = 41.6 bits (96), Expect = 0.001
Identities = 60/299 (20%), Positives = 129/299 (43%), Gaps = 33/299 (11%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEV 124
+ E+ AK + Q+ L + ++ K+ LE+ E + ++ + ++Q +E
Sbjct: 1346 EEEEEAKHNLEKQIATLHA-QVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEK 1404
Query: 125 SNLQDIMHDIQNN-EEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQ 183
D + + ++ L + L+ + Q+ + K+ + + + AK+ +
Sbjct: 1405 VAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEER 1464
Query: 184 VTVQINSAEQEIKLLTERLKDLEDST-----LRNIRTVKRQEEEDLLRVEEQLGSDTKAI 238
+ + E+E K L+ + LE++ L + R E EDL+ ++ +G K++
Sbjct: 1465 DRAEAEAREKETKALS-LARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG---KSV 1520
Query: 239 EKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSV----LRVSQDLIETE 294
+LE+ + AL E +VEE KT L +E + + LR+ +L +
Sbjct: 1521 HELEKSKRAL--------------EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMK 1566
Query: 295 KKME-DLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSI---LKMQNELDILKEKVH 349
+ E DL + E+ + V ++ EM+ LE + S+ + + E+D+ + H
Sbjct: 1567 AQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAH 1625
Score = 38.5 bits (88), Expect = 0.010
Identities = 54/285 (18%), Positives = 119/285 (41%), Gaps = 41/285 (14%)
Query: 77 QLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQN 136
QL KL+ Q++ + + + S E IL +A + + E E+ LQ+ + +
Sbjct: 1639 QLRKLQA----QMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694
Query: 137 NEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIK 196
+ Q L ++ N + +LEE K + +Q+ ++ + +
Sbjct: 1695 AKRQAQQERDELADEIANSSGKGALALEE--------KRRLEARIAQLEEELEEEQGNTE 1746
Query: 197 LLTERLK--DLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIE-KLEEEQHALFARDE 253
L+ +RLK +L+ + ++R + +QL K ++ KL+E + +
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTV----- 1801
Query: 254 DLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQ----DLIETEKKMEDLTMQMFN--- 306
S Y+ + + + +E + + + Q + TEKK++D+ +Q+ +
Sbjct: 1802 -----KSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERR 1856
Query: 307 ----MEDDMLKAVSEIMEMQKTLEGIQYD-----NSILKMQNELD 342
+D KA + + ++++ LE + + S K+Q EL+
Sbjct: 1857 NAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELE 1901
Score = 30.4 bits (67), Expect = 2.7
Identities = 36/189 (19%), Positives = 75/189 (39%), Gaps = 18/189 (9%)
Query: 85 EFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQR 144
E ++ Q LI+++L+ + + + ++L Q+ N + + +V Q
Sbjct: 1737 ELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQE 1796
Query: 145 MQ-SLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLL----- 198
M+ ++ K++ + + ++ D +E K Q+ E+++K +
Sbjct: 1797 MEGTVKSKYKASITALEAKIAQLEEQLD---NETKE-RQAACKQVRRTEKKLKDVLLQVD 1852
Query: 199 -----TERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDE 253
E+ KD D ++ +KRQ EE + S K +LE+ A +
Sbjct: 1853 DERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNR 1912
Query: 254 D---LTNKL 259
+ L NKL
Sbjct: 1913 EVSSLKNKL 1921
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 66.2 bits (160), Expect = 4e-11
Identities = 64/308 (20%), Positives = 148/308 (48%), Gaps = 40/308 (12%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN 126
EK KVE + + ++ + QQL + ++++E+L++ + EA + + +QE
Sbjct: 866 EKQTKVEGELEEME---RKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQE--- 919
Query: 127 LQDIMHDIQNN---EEVLTQRMQSLNEKFQ-NITDFWKRSLEE------MNINTDIFKSE 176
L++I+HD+++ EE Q +Q+ +K Q +I D ++ EE + + +++
Sbjct: 920 LEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAK 979
Query: 177 AKHIHSQVTV---QINSAEQEIKLLTERLKDL------EDSTLRNIRTVKRQEEEDLLRV 227
K + ++ + Q + +E KL+ +R+ + E+ +N+ ++ ++E + +
Sbjct: 980 IKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDL 1039
Query: 228 EEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVS 287
EE+L + K ++LE+ + L DL +++++ + +++E K L E + L
Sbjct: 1040 EERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGAL--- 1096
Query: 288 QDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQ-----NELD 342
+ +D T+ N + + ++I E+Q+ E + + + Q EL+
Sbjct: 1097 -------ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149
Query: 343 ILKEKVHD 350
LK ++ D
Sbjct: 1150 ALKTELED 1157
Score = 51.6 bits (122), Expect = 1e-06
Identities = 68/322 (21%), Positives = 140/322 (43%), Gaps = 53/322 (16%)
Query: 68 KFAKVENQYQLLKLETNEFQQLQSKISLISEKLEST-ESILQEATSSMSLMTQFEQEVSN 126
+ A+++ ++ K N+ ++ + +S E L++ E L + L T+ EQEV+
Sbjct: 1119 QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAE 1178
Query: 127 LQDIMHDIQNNEEVLTQRM--------QSLNEKFQNITDFWKRSLE--EMNINTD----- 171
L+ + + N E Q M + L+E+ + F K +LE + + TD
Sbjct: 1179 LKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRF-KANLEKNKQGLETDNKELA 1237
Query: 172 -------IFKSEAKHIHSQVTVQINSAEQEIK-------LLTERLKDLEDSTLRNIRTVK 217
K+E++H ++ Q+ ++ L E+ L++ L N+ T+
Sbjct: 1238 CEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNE-LDNVSTLL 1296
Query: 218 RQEE-------EDLLRVEEQLGSDTKAIEKLEEEQHALFARD---EDLTNKLSDYEPKVE 267
+ E +D +E QL + +++ ++ L +R E+ N L + + + E
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEE 1356
Query: 268 ECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLE- 326
E + +L VL + L +T+KK++D + ++E+ K + + + + LE
Sbjct: 1357 EARKNLE------KQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
Query: 327 -GIQYD---NSILKMQNELDIL 344
+ YD + ++Q ELD L
Sbjct: 1411 KALAYDKLEKTKNRLQQELDDL 1432
Score = 44.3 bits (103), Expect = 2e-04
Identities = 50/259 (19%), Positives = 107/259 (41%), Gaps = 37/259 (14%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLIS--------EKLESTESILQEATSSMSL 116
+ E FA+ + + LK E QLQ +++ E+ E + I A+ +L
Sbjct: 1668 RDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSAL 1727
Query: 117 MTQ---FEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIF 173
+ + E ++ L++ + + Q+N E+L R F K +L+ +N ++
Sbjct: 1728 LDEKRRLEARIAQLEEELEEEQSNMELLNDR-------------FRKTTLQVDTLNAELA 1774
Query: 174 KSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGS 233
+ S Q E++ K L +L++LE + + E + ++EEQL
Sbjct: 1775 AERSAAQKSDNARQ--QLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ 1832
Query: 234 D-------TKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLP----TIESAIHS 282
+ K + + E++ +F + ED Y+ ++E+ + +E A
Sbjct: 1833 EAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEE 1892
Query: 283 VLRVSQDLIETEKKMEDLT 301
R + + +++++D T
Sbjct: 1893 ATRANASRRKLQRELDDAT 1911
Score = 40.0 bits (92), Expect = 0.003
Identities = 70/345 (20%), Positives = 149/345 (43%), Gaps = 58/345 (16%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEV-SNL---Q 128
E + +LLK Q+L+ K +L +KLE T++ LQ+ +++ +++V SNL Q
Sbjct: 1392 EAKKKLLKDAEALSQRLEEK-ALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQ 1450
Query: 129 DIMHDIQNNEEVLTQR----------------------MQSLNEKFQNITDFWKRSLEEM 166
+ E+ ++ R ++L E + +F +++ +
Sbjct: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLR 1510
Query: 167 NINTDIFKSE---AKHIHS------QVTVQINSAEQEIKLLTERLKDLEDSTLR---NIR 214
D+ S+ K++H + Q+ +++ L + L+ ED+ LR N++
Sbjct: 1511 ADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 215 TVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLP 274
+K Q E DL +EQ + + K E L A ED + + ++ + L
Sbjct: 1571 AMKAQFERDLQTRDEQNEEKKRLLIKQVRE---LEAELEDERKQRALAVASKKKMEIDLK 1627
Query: 275 TIESAIHSVLRVSQDLIETEKK----MEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQY 330
+E+ I + + ++I+ +K M+D ++ + ++ E +K L+ ++
Sbjct: 1628 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEA 1687
Query: 331 DNSILKMQNEL----------DILKEKVHDFIAYSSTGEKGTLKE 365
+ IL++Q EL + ++++ D I S++G+ L E
Sbjct: 1688 E--ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDE 1730
Score = 39.3 bits (90), Expect = 0.006
Identities = 39/194 (20%), Positives = 96/194 (49%), Gaps = 15/194 (7%)
Query: 186 VQINSAEQEIKLLTERLKDLEDSTLR---NIRTVKRQ-----EEEDLLRVEEQLGSDTKA 237
+Q+ E+E++ E L +++ + + ++R+ EE+++L EQL ++T+
Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILA--EQLQAETEL 902
Query: 238 IEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKM 297
+ EE + L A+ ++L L D E +VEE + +++ + QDL E+++
Sbjct: 903 FAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDL---EEQL 959
Query: 298 EDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSST 357
++ ++ + + A ++I +M++ + ++ NS K E ++++++ + + +
Sbjct: 960 DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNS--KFIKEKKLMEDRIAECSSQLAE 1017
Query: 358 GEKGTLKEYNIENK 371
E+ I NK
Sbjct: 1018 EEEKAKNLAKIRNK 1031
Score = 35.8 bits (81), Expect = 0.065
Identities = 34/188 (18%), Positives = 87/188 (46%), Gaps = 15/188 (7%)
Query: 81 LETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVS-NLQDIMHDIQNNEE 139
L+T + +Q + K L+ +++ E+ L++ +L ++++ +L+D+ I+ +
Sbjct: 1580 LQTRD-EQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANK 1638
Query: 140 VLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLT 199
+ ++ L + + D+ +R LEE + D ++ Q +E+++K L
Sbjct: 1639 ARDEVIKQLRKLQAQMKDY-QRELEEARASRD-----------EIFAQSKESEKKLKSLE 1686
Query: 200 ERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKL 259
+ L++ L + +R E++ + +++ + L +E+ L AR L +L
Sbjct: 1687 AEILQLQEE-LASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEEL 1745
Query: 260 SDYEPKVE 267
+ + +E
Sbjct: 1746 EEEQSNME 1753
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 66.2 bits (160), Expect = 4e-11
Identities = 67/304 (22%), Positives = 137/304 (45%), Gaps = 35/304 (11%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN 126
EK ++ Q Q + +L ++ K++ E+IL+ S + EQ++
Sbjct: 1090 EKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILE 1149
Query: 127 LQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTV 186
+ I+ ++ N L + + L + +N D +++E+ + +I + + +
Sbjct: 1150 KESIILKLERN---LKEFQEHLQDSVKNTKDL---NVKELKLKEEITQLTNNLQDMKHLL 1203
Query: 187 QINSAEQEI-KLLTERLKD-LEDSTLR--NIRTVKRQEEEDLLRVEEQLGSDTKAIEKLE 242
Q+ E+E + TE+LK+ L S+ R N++ +++EED ++E+L K I++++
Sbjct: 1204 QLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQ 1263
Query: 243 EEQHALFARDEDLTNKLSDYEPKVEECKTHLPT----------------IESAIHSVLRV 286
+E + D+ L K+++ E K +C L +E AI R
Sbjct: 1264 KEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERA 1323
Query: 287 SQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKE 346
+DL EK +ED+ M +E+ V + ++ LE ++ ++ EL+ KE
Sbjct: 1324 CKDLNVKEKIIEDMRM---TLEEQEQTQVEQDQVLEAKLEEVE------RLATELEKWKE 1374
Query: 347 KVHD 350
K +D
Sbjct: 1375 KCND 1378
Score = 61.2 bits (147), Expect = 1e-09
Identities = 66/303 (21%), Positives = 142/303 (46%), Gaps = 28/303 (9%)
Query: 64 QQSEKFAKVENQYQLLKLE-TNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQ 122
+Q EK K+ N+ + TN Q++ + I E L + +S+ Q + + +
Sbjct: 916 EQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDE-LRTLDSVSQISNIDLLNLRDLSN 974
Query: 123 --EVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEM-NINTDIFKSEAKH 179
E NL + D+ N+ +++++++ + N + + S+E + +I K+ +K
Sbjct: 975 GSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKK 1034
Query: 180 IHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIE 239
H QI EQ+I+ L +K +D R ++ + + ++DLL+ +E L K E
Sbjct: 1035 SH-----QIEELEQQIEKLQAEVKGYKDENNR-LKEKEHKNQDDLLKEKETLIQQLK--E 1086
Query: 240 KLEEE--------QHALFARD--EDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQD 289
+L+E+ QH + + +LT ++ Y+ K++E +T L T + ++ QD
Sbjct: 1087 ELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQD 1146
Query: 290 LIETEKKMEDLTMQMFNMEDDMLKAVS-----EIMEMQKTLEGIQYDNSILKMQNELDIL 344
++E E + L + ++ + +V + E++ E Q N++ M++ L +
Sbjct: 1147 ILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLK 1206
Query: 345 KEK 347
+E+
Sbjct: 1207 EEE 1209
Score = 53.5 bits (127), Expect = 3e-07
Identities = 75/317 (23%), Positives = 150/317 (47%), Gaps = 48/317 (15%)
Query: 64 QQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQE 123
++S + ++E Q + L+ E ++ +++ ++ ++ + +L+E + L+ Q ++E
Sbjct: 1033 KKSHQIEELEQQIEKLQAEVKGYKDENNRLK--EKEHKNQDDLLKEKET---LIQQLKEE 1087
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQ 183
+ +++ D+Q V +R +L+E Q +T + K ++E+ + K E H ++
Sbjct: 1088 LQE-KNVTLDVQIQHVVEGKR--ALSELTQGVTCY-KAKIKELETILETQKVECSH-SAK 1142
Query: 184 VTVQINSAEQEIKLLTERLKD----LEDSTLR----NIRTVKRQEE-----------EDL 224
+ I E I L LK+ L+DS N++ +K +EE + L
Sbjct: 1143 LEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHL 1202
Query: 225 LRV-EEQLGSDTKAIEKLEEEQHALFARDE----DLTNKLSDY---EPKVEECKTHLPTI 276
L++ EE+ ++ + EKL+EE A AR + DL K DY + K+ + K + +
Sbjct: 1203 LQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQV 1262
Query: 277 ESAIHSVLRVSQDLI-----ETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYD 331
+ + SV+R L+ E EKK + ++ +M+ ++ + E + QK E IQ
Sbjct: 1263 QKEV-SVMRDEDKLLRIKINELEKKKNQCSQEL-DMKQRTIQQLKEQLNNQKVEEAIQQY 1320
Query: 332 NSILKMQNELDILKEKV 348
K N +KEK+
Sbjct: 1321 ERACKDLN----VKEKI 1333
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 63.5 bits (153), Expect = 3e-10
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 34/294 (11%)
Query: 83 TNEFQQLQSKISLISEKLES-----------TESILQEATSSMSLMTQFEQEVSNLQDIM 131
T QLQ K L++ E T+ ++ E S ++T+ + + L+
Sbjct: 328 TTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEH 387
Query: 132 HDIQNNEEVLTQRMQSLNEKFQNITDFWKRSL----EEMNINTDIFKSEAKHIHSQVTVQ 187
+ QN V Q Q + KFQ + + + + +E I D + + S+ + +
Sbjct: 388 NVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAE 447
Query: 188 INSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHA 247
+N Q+ L L + +T K Q+EE + EQ + K +L+E +
Sbjct: 448 LNKLRQDYARLVNELTE---------KTGKLQQEEVQKKNAEQAATQLKV--QLQEAERR 496
Query: 248 LFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMF-- 305
+ + +++E ++ ++ E+ + S+ D + +++++E MQ+
Sbjct: 497 WEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMES 556
Query: 306 -----NMEDDMLKAVSEIMEMQKTLEG-IQYDNSILKMQNELDILKEKVHDFIA 353
N E+ + V +I+E + L+ IQ +S + Q +L E++H IA
Sbjct: 557 EQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIA 610
Score = 55.5 bits (132), Expect = 8e-08
Identities = 68/321 (21%), Positives = 146/321 (45%), Gaps = 35/321 (10%)
Query: 75 QYQLLKLETNEFQQ---LQSKISLISEKLEST--ESILQEATSSMSLMTQFEQEVSNLQD 129
Q + LK + +F Q+ S+++E+L E Q + SL ++ ++ S ++
Sbjct: 577 QNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 636
Query: 130 IMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQIN 189
+ DIQN +L +Q L + N LE+M + + + + + Q+ +I+
Sbjct: 637 LK-DIQNMNFLLKAEVQKL-QALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEIS 694
Query: 190 SAEQEIKLLTERLKDLEDSTLRNIRTVK----------------RQEEEDLLRVEEQLGS 233
+ +E K+L ++ K L+ S ++ ++T+ ++++E L VEE L +
Sbjct: 695 NKMEEFKILNDQNKALK-SEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLET 753
Query: 234 DTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIET 293
+ EEE +A+ + LT ++ D + K + + +E + +
Sbjct: 754 GLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSV 813
Query: 294 EKKMEDLTMQMFNMEDDM-LKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFI 352
E+ +E +++ N E + L S++ E+Q L+G + + +K +L+EK D
Sbjct: 814 EELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKA-----VLEEKEKDL- 867
Query: 353 AYSSTGEKGTLKEYNIENKGI 373
++TG+ L++ EN+ +
Sbjct: 868 --ANTGK--WLQDLQEENESL 884
Score = 48.5 bits (114), Expect = 1e-05
Identities = 67/322 (20%), Positives = 144/322 (44%), Gaps = 50/322 (15%)
Query: 62 VFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFE 121
+ + E+F + +Q + LK E + Q L S+ + +E E +QE + + +
Sbjct: 693 ISNKMEEFKILNDQNKALKSEVQKLQTLVSE-QPNKDVVEQMEKCIQEKDEKLKTVEELL 751
Query: 122 Q----EVSNLQDIMHDIQNNEEVLTQRMQSLNEK------FQNITDFWKRSLEEMNINT- 170
+ +V+ ++ ++ I+ LT+ +Q L K F ++ + K+ + E +
Sbjct: 752 ETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIK 811
Query: 171 ---DIFKSEA-KHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLR 226
++ ++E K + + TVQ+ S +++ L LK E+ + ++ V ++E+DL
Sbjct: 812 SVEELLEAELLKVANKEKTVQL-SITSKVQELQNLLKGKEEQ-MNTMKAVLEEKEKDLAN 869
Query: 227 V----------EEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTI 276
E L + + + + ++ + ++ E+L L + E +++ + L
Sbjct: 870 TGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKER 929
Query: 277 ESAIHSVLRVSQDLIETEK----KMEDLTMQ------MFNMEDDMLKAVSEIMEMQKTLE 326
ES + S ++ QD+ + K ++E L Q F +++LK +S E +K +
Sbjct: 930 ESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVIS---EREKEIS 986
Query: 327 GIQYDNSILKMQNELDILKEKV 348
G + NELD LK+ V
Sbjct: 987 G---------LWNELDSLKDAV 999
Score = 47.4 bits (111), Expect = 2e-05
Identities = 59/326 (18%), Positives = 142/326 (43%), Gaps = 29/326 (8%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLM-TQFEQE 123
+ E+ ++N LLK E + Q L ++ + + +LE + + + L+ Q + E
Sbjct: 633 KEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 692
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSL-----NEKFQNITDFWKRSLEEMNINTDIFKSEAK 178
+SN + + + + L +Q L + +++ + ++ ++E + + +
Sbjct: 693 ISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLE 752
Query: 179 HIHSQVTV---QINSAEQEIKLLTERLKDLE---------DSTLRNIRTVKRQEEEDLLR 226
QV ++N+ E LT+ ++DL+ S + ++ V +++ +
Sbjct: 753 TGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKS 812
Query: 227 VEEQLGSD-TKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLR 285
VEE L ++ K K + Q ++ ++ ++L N L E ++ K L E + + +
Sbjct: 813 VEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGK 872
Query: 286 VSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILK 345
QDL E + ++ ++ + S+ E++ L+ + +N + +++ +LK
Sbjct: 873 WLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLK--EKENELKRLE---AMLK 927
Query: 346 EKVHDFIAYSSTGEKGTLKEYNIENK 371
E+ D + + L++ ENK
Sbjct: 928 ERESDL-----SSKTQLLQDVQDENK 948
Score = 42.7 bits (99), Expect = 5e-04
Identities = 51/268 (19%), Positives = 112/268 (41%), Gaps = 10/268 (3%)
Query: 71 KVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDI 130
K+ YQ + +FQQ++ ++ L+ IL++A S+ + + +Q + L +
Sbjct: 393 KIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQS-AELNKL 451
Query: 131 MHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINS 190
D LT++ L ++ + K++ E+ + EA+ +V I
Sbjct: 452 RQDYARLVNELTEKTGKLQQE-----EVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 506
Query: 191 AEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFA 250
E + + L+ + ++++ + D L ++QL + + ++ +E EQ +
Sbjct: 507 RTAEHEAAQQDLQSKFVAKENEVQSL-HSKLTDTLVSKQQL--EQRLMQLMESEQKRV-N 562
Query: 251 RDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDD 310
++E L ++ D + E K + S I + S E K + + Q+ ED
Sbjct: 563 KEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDS 622
Query: 311 MLKAVSEIMEMQKTLEGIQYDNSILKMQ 338
+ + ++ L+ IQ N +LK +
Sbjct: 623 LASERDRLTSKEEELKDIQNMNFLLKAE 650
Score = 38.9 bits (89), Expect = 0.008
Identities = 56/276 (20%), Positives = 113/276 (40%), Gaps = 30/276 (10%)
Query: 73 ENQYQLLKLETNE-FQQLQSKISLIS-----EKLESTESILQEATSSMSLMTQFEQEVSN 126
+ Q + ++LE E ++L K+S+ S E L E +E + T +EV
Sbjct: 1039 QQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAG----TSGSEEVKV 1094
Query: 127 LQDIMHDIQNNEEVLT------QRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
L+ H ++ +E+ T ++ +S+ + + I +RS+E+ + E+
Sbjct: 1095 LE---HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKT 1151
Query: 181 HSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK 240
Q+ S+EQE++ L KD+E N+R + E +L + E + + + +
Sbjct: 1152 IKQMQSSFTSSEQELERLRSENKDIE-----NLRREREHLEMELEKAEMERSTYVTEVRE 1206
Query: 241 LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAI------HSVLRVSQDLIETE 294
L+ + + + N+ + + + L I+S I +V+ S ETE
Sbjct: 1207 LKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETE 1266
Query: 295 KKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQY 330
++ N L+ + + + Q T E Y
Sbjct: 1267 SSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHY 1302
Score = 32.0 bits (71), Expect = 0.94
Identities = 45/263 (17%), Positives = 109/263 (41%), Gaps = 46/263 (17%)
Query: 98 EKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITD 157
E L STE +LQ+ + S Q + E L+ +EVL + ++
Sbjct: 1018 EALASTEKMLQDKVNKTSKERQQQVEAVELE--------AKEVLKKLFPKVSVPSNLSYG 1069
Query: 158 FWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVK 217
W F+ +AK + S +E+K+L +LK+ ++ + + ++
Sbjct: 1070 EWLHG----------FEKKAKECMAG-----TSGSEEVKVLEHKLKEADE--MHTLLQLE 1112
Query: 218 RQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIE 277
++ + +L ++T+ I L++ Q ++ + K+ + +++ ++ + E
Sbjct: 1113 CEKYKSVL-------AETEGI--LQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSE 1163
Query: 278 SAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTL------------ 325
+ + ++D+ ++ E L M++ E + V+E+ E++ L
Sbjct: 1164 QELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQN 1223
Query: 326 EGIQYDNSILKMQNELDILKEKV 348
E + + K Q L++++ K+
Sbjct: 1224 ERQKVAGDLHKAQQSLELIQSKI 1246
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 63.5 bits (153), Expect = 3e-10
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 34/294 (11%)
Query: 83 TNEFQQLQSKISLISEKLES-----------TESILQEATSSMSLMTQFEQEVSNLQDIM 131
T QLQ K L++ E T+ ++ E S ++T+ + + L+
Sbjct: 328 TTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEH 387
Query: 132 HDIQNNEEVLTQRMQSLNEKFQNITDFWKRSL----EEMNINTDIFKSEAKHIHSQVTVQ 187
+ QN V Q Q + KFQ + + + + +E I D + + S+ + +
Sbjct: 388 NVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAE 447
Query: 188 INSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHA 247
+N Q+ L L + +T K Q+EE + EQ + K +L+E +
Sbjct: 448 LNKLRQDYARLVNELTE---------KTGKLQQEEVQKKNAEQAATQLKV--QLQEAERR 496
Query: 248 LFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMF-- 305
+ + +++E ++ ++ E+ + S+ D + +++++E MQ+
Sbjct: 497 WEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMES 556
Query: 306 -----NMEDDMLKAVSEIMEMQKTLEG-IQYDNSILKMQNELDILKEKVHDFIA 353
N E+ + V +I+E + L+ IQ +S + Q +L E++H IA
Sbjct: 557 EQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIA 610
Score = 54.3 bits (129), Expect = 2e-07
Identities = 74/344 (21%), Positives = 155/344 (45%), Gaps = 58/344 (16%)
Query: 75 QYQLLKLETNEFQQ---LQSKISLISEKLEST--ESILQEATSSMSLMTQFEQEVSNLQD 129
Q + LK + +F Q+ S+++E+L E Q + SL ++ ++ S ++
Sbjct: 577 QNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 636
Query: 130 IMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQIN 189
+ DIQN +L +Q L + N LE+M + + + + + Q+ +I+
Sbjct: 637 LK-DIQNMNFLLKAEVQKL-QALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEIS 694
Query: 190 SAEQEIKLLTERLKDLEDSTLRNIRTVK----------------RQEEEDLLRVEEQLGS 233
+ +E K+L ++ K L+ S ++ ++T+ ++++E L VEE L +
Sbjct: 695 NKMEEFKILNDQNKALK-SEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLET 753
Query: 234 DTKAIEKLEEEQHALFARDEDLTNKLSDYEPK----------VEECKTHLPTIESAIHSV 283
+ EEE +A+ + LT ++ D + K VEE K + + I SV
Sbjct: 754 GLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSV 813
Query: 284 LRVSQ----DLIETEKKMEDLTMQMFNMEDDM----------LKAVSEIMEMQKTLEGIQ 329
+ + + EK ++DL ++ +++++ L S++ E+Q L+G +
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Query: 330 YDNSILKMQNELDILKEKVHDFIAYSSTGEKGTLKEYNIENKGI 373
+ +K +L+EK D ++TG+ L++ EN+ +
Sbjct: 874 EQMNTMKA-----VLEEKEKDL---ANTGK--WLQDLQEENESL 907
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/281 (17%), Positives = 121/281 (43%), Gaps = 14/281 (4%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLM-TQFEQE 123
+ E+ ++N LLK E + Q L ++ + + +LE + + + L+ Q + E
Sbjct: 633 KEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 692
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSL-----NEKFQNITDFWKRSLEEMNINTDIFKSEAK 178
+SN + + + + L +Q L + +++ + ++ ++E + + +
Sbjct: 693 ISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLE 752
Query: 179 HIHSQVTV---QINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDT 235
QV ++N+ E LT+ ++DL+ +N + E+L +V +
Sbjct: 753 TGLIQVATKEEELNAIRTENSSLTKEVQDLK--AKQNDQVSFASLVEELKKVIHEKDGKI 810
Query: 236 KAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEK 295
K++E+L E + A E + D + +++ K + ++ L ++ + E +
Sbjct: 811 KSVEELLEAELLKVANKE---KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQN 867
Query: 296 KMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILK 336
++ QM M+ + + ++ K L+ +Q +N LK
Sbjct: 868 LLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Score = 46.2 bits (108), Expect = 5e-05
Identities = 61/301 (20%), Positives = 134/301 (44%), Gaps = 36/301 (11%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN 126
EK K++ +LL+ + + +++ I + S +Q+ + + F V
Sbjct: 739 EKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEE 798
Query: 127 LQDIMHD----IQNNEEVLTQRMQSLNEKFQNITDFWK--RSLEEMNINTDIFKSEAKHI 180
L+ ++H+ I++ EE+L + + K + + D + ++L+E N + K++ I
Sbjct: 799 LKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSI 858
Query: 181 HSQVTVQIN---SAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKA 237
S+V N E+++ + L++ E + ++ +EE E L + +
Sbjct: 859 TSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEE-----NESLKAHVQE 913
Query: 238 IEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEK-- 295
+ + ++ + ++ E+L L + E +++ + L ES + S ++ QD+ + K
Sbjct: 914 VAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLF 973
Query: 296 --KMEDLTMQ------MFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEK 347
++E L Q F +++LK +S E +K + G + NELD LK+
Sbjct: 974 KSQIEQLKQQNYQQASSFPPHEELLKVIS---EREKEISG---------LWNELDSLKDA 1021
Query: 348 V 348
V
Sbjct: 1022 V 1022
Score = 42.7 bits (99), Expect = 5e-04
Identities = 51/268 (19%), Positives = 112/268 (41%), Gaps = 10/268 (3%)
Query: 71 KVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDI 130
K+ YQ + +FQQ++ ++ L+ IL++A S+ + + +Q + L +
Sbjct: 393 KIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQS-AELNKL 451
Query: 131 MHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINS 190
D LT++ L ++ + K++ E+ + EA+ +V I
Sbjct: 452 RQDYARLVNELTEKTGKLQQE-----EVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 506
Query: 191 AEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFA 250
E + + L+ + ++++ + D L ++QL + + ++ +E EQ +
Sbjct: 507 RTAEHEAAQQDLQSKFVAKENEVQSL-HSKLTDTLVSKQQL--EQRLMQLMESEQKRV-N 562
Query: 251 RDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDD 310
++E L ++ D + E K + S I + S E K + + Q+ ED
Sbjct: 563 KEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDS 622
Query: 311 MLKAVSEIMEMQKTLEGIQYDNSILKMQ 338
+ + ++ L+ IQ N +LK +
Sbjct: 623 LASERDRLTSKEEELKDIQNMNFLLKAE 650
Score = 40.8 bits (94), Expect = 0.002
Identities = 60/303 (19%), Positives = 133/303 (43%), Gaps = 52/303 (17%)
Query: 73 ENQYQLLKLETNE-FQQLQSKISLIS-----EKLESTESILQEATSSMSLMTQFEQEVSN 126
+ Q + ++LE E ++L K+S+ S E L E +E + T +EV
Sbjct: 1062 QQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAG----TSGSEEVKV 1117
Query: 127 LQDIMHDIQNNEEVLT------QRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
L+ H ++ +E+ T ++ +S+ + + I +RS+E+ + E+
Sbjct: 1118 LE---HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKT 1174
Query: 181 HSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK 240
Q+ S+EQE++ L KD+E N+R E + L +E +EK
Sbjct: 1175 IKQMQSSFTSSEQELERLRSENKDIE-----NLR-----REREHLEME---------LEK 1215
Query: 241 LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDL 300
E E+ +L + L++ + K+++ + +R +++L + ++ +
Sbjct: 1216 AEMERSTYVTEVRELKDLLTELQKKLDD----------SYSEAVRQNEELNLLKAQLNET 1265
Query: 301 TMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEK 360
++ +++ K ++ + Q++LE IQ + I+K + +++ D + + EK
Sbjct: 1266 LTKLRTEQNERQKVAGDLHKAQQSLELIQ--SKIVKAAGDTTVIENS--DVSPETESSEK 1321
Query: 361 GTL 363
T+
Sbjct: 1322 ETM 1324
Score = 35.0 bits (79), Expect = 0.11
Identities = 57/362 (15%), Positives = 153/362 (42%), Gaps = 84/362 (23%)
Query: 62 VFQQSEKFAKVENQYQ----LLKLETNEFQQLQSKISLISEKLESTESILQEATSS---- 113
V Q + K A +Q++ +LK + NE ++L++ + L S +LQ+
Sbjct: 914 VAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLF 973
Query: 114 ------------------------MSLMTQFEQEVSNLQDIMHDI---------QNNE-- 138
+ ++++ E+E+S L + + + +NN+
Sbjct: 974 KSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLR 1033
Query: 139 EVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQIN--------- 189
E + M++L + + D ++ +E + + EAK + ++ +++
Sbjct: 1034 EKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGE 1093
Query: 190 ----------------SAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGS 233
S +E+K+L +LK+ ++ + + ++ ++ + +L +
Sbjct: 1094 WLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADE--MHTLLQLECEKYKSVL-------A 1144
Query: 234 DTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIET 293
+T+ I L++ Q ++ + K+ + +++ ++ + E + + ++D+
Sbjct: 1145 ETEGI--LQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENL 1202
Query: 294 EKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQ--YDNS---ILKMQNELDILKEKV 348
++ E L M++ E + V+E+ E++ L +Q D+S ++ EL++LK ++
Sbjct: 1203 RREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQL 1262
Query: 349 HD 350
++
Sbjct: 1263 NE 1264
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 63.5 bits (153), Expect = 3e-10
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 34/294 (11%)
Query: 83 TNEFQQLQSKISLISEKLES-----------TESILQEATSSMSLMTQFEQEVSNLQDIM 131
T QLQ K L++ E T+ ++ E S ++T+ + + L+
Sbjct: 328 TTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEH 387
Query: 132 HDIQNNEEVLTQRMQSLNEKFQNITDFWKRSL----EEMNINTDIFKSEAKHIHSQVTVQ 187
+ QN V Q Q + KFQ + + + + +E I D + + S+ + +
Sbjct: 388 NVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAE 447
Query: 188 INSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHA 247
+N Q+ L L + +T K Q+EE + EQ + K +L+E +
Sbjct: 448 LNKLRQDYARLVNELTE---------KTGKLQQEEVQKKNAEQAATQLKV--QLQEAERR 496
Query: 248 LFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMF-- 305
+ + +++E ++ ++ E+ + S+ D + +++++E MQ+
Sbjct: 497 WEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMES 556
Query: 306 -----NMEDDMLKAVSEIMEMQKTLEG-IQYDNSILKMQNELDILKEKVHDFIA 353
N E+ + V +I+E + L+ IQ +S + Q +L E++H IA
Sbjct: 557 EQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIA 610
Score = 54.3 bits (129), Expect = 2e-07
Identities = 74/344 (21%), Positives = 155/344 (45%), Gaps = 58/344 (16%)
Query: 75 QYQLLKLETNEFQQ---LQSKISLISEKLEST--ESILQEATSSMSLMTQFEQEVSNLQD 129
Q + LK + +F Q+ S+++E+L E Q + SL ++ ++ S ++
Sbjct: 577 QNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 636
Query: 130 IMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQIN 189
+ DIQN +L +Q L + N LE+M + + + + + Q+ +I+
Sbjct: 637 LK-DIQNMNFLLKAEVQKL-QALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEIS 694
Query: 190 SAEQEIKLLTERLKDLEDSTLRNIRTVK----------------RQEEEDLLRVEEQLGS 233
+ +E K+L ++ K L+ S ++ ++T+ ++++E L VEE L +
Sbjct: 695 NKMEEFKILNDQNKALK-SEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLET 753
Query: 234 DTKAIEKLEEEQHALFARDEDLTNKLSDYEPK----------VEECKTHLPTIESAIHSV 283
+ EEE +A+ + LT ++ D + K VEE K + + I SV
Sbjct: 754 GLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSV 813
Query: 284 LRVSQ----DLIETEKKMEDLTMQMFNMEDDM----------LKAVSEIMEMQKTLEGIQ 329
+ + + EK ++DL ++ +++++ L S++ E+Q L+G +
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Query: 330 YDNSILKMQNELDILKEKVHDFIAYSSTGEKGTLKEYNIENKGI 373
+ +K +L+EK D ++TG+ L++ EN+ +
Sbjct: 874 EQMNTMKA-----VLEEKEKDL---ANTGK--WLQDLQEENESL 907
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/281 (17%), Positives = 121/281 (43%), Gaps = 14/281 (4%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLM-TQFEQE 123
+ E+ ++N LLK E + Q L ++ + + +LE + + + L+ Q + E
Sbjct: 633 KEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 692
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSL-----NEKFQNITDFWKRSLEEMNINTDIFKSEAK 178
+SN + + + + L +Q L + +++ + ++ ++E + + +
Sbjct: 693 ISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLE 752
Query: 179 HIHSQVTV---QINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDT 235
QV ++N+ E LT+ ++DL+ +N + E+L +V +
Sbjct: 753 TGLIQVATKEEELNAIRTENSSLTKEVQDLK--AKQNDQVSFASLVEELKKVIHEKDGKI 810
Query: 236 KAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEK 295
K++E+L E + A E + D + +++ K + ++ L ++ + E +
Sbjct: 811 KSVEELLEAELLKVANKE---KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQN 867
Query: 296 KMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILK 336
++ QM M+ + + ++ K L+ +Q +N LK
Sbjct: 868 LLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Score = 46.2 bits (108), Expect = 5e-05
Identities = 61/301 (20%), Positives = 134/301 (44%), Gaps = 36/301 (11%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN 126
EK K++ +LL+ + + +++ I + S +Q+ + + F V
Sbjct: 739 EKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEE 798
Query: 127 LQDIMHD----IQNNEEVLTQRMQSLNEKFQNITDFWK--RSLEEMNINTDIFKSEAKHI 180
L+ ++H+ I++ EE+L + + K + + D + ++L+E N + K++ I
Sbjct: 799 LKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSI 858
Query: 181 HSQVTVQIN---SAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKA 237
S+V N E+++ + L++ E + ++ +EE E L + +
Sbjct: 859 TSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEE-----NESLKAHVQE 913
Query: 238 IEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEK-- 295
+ + ++ + ++ E+L L + E +++ + L ES + S ++ QD+ + K
Sbjct: 914 VAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLF 973
Query: 296 --KMEDLTMQ------MFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEK 347
++E L Q F +++LK +S E +K + G + NELD LK+
Sbjct: 974 KSQIEQLKQQNYQQASSFPPHEELLKVIS---EREKEISG---------LWNELDSLKDA 1021
Query: 348 V 348
V
Sbjct: 1022 V 1022
Score = 42.7 bits (99), Expect = 5e-04
Identities = 51/268 (19%), Positives = 112/268 (41%), Gaps = 10/268 (3%)
Query: 71 KVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDI 130
K+ YQ + +FQQ++ ++ L+ IL++A S+ + + +Q + L +
Sbjct: 393 KIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQS-AELNKL 451
Query: 131 MHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINS 190
D LT++ L ++ + K++ E+ + EA+ +V I
Sbjct: 452 RQDYARLVNELTEKTGKLQQE-----EVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 506
Query: 191 AEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFA 250
E + + L+ + ++++ + D L ++QL + + ++ +E EQ +
Sbjct: 507 RTAEHEAAQQDLQSKFVAKENEVQSL-HSKLTDTLVSKQQL--EQRLMQLMESEQKRV-N 562
Query: 251 RDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDD 310
++E L ++ D + E K + S I + S E K + + Q+ ED
Sbjct: 563 KEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDS 622
Query: 311 MLKAVSEIMEMQKTLEGIQYDNSILKMQ 338
+ + ++ L+ IQ N +LK +
Sbjct: 623 LASERDRLTSKEEELKDIQNMNFLLKAE 650
Score = 40.4 bits (93), Expect = 0.003
Identities = 59/287 (20%), Positives = 118/287 (41%), Gaps = 30/287 (10%)
Query: 62 VFQQSEKFAKVENQYQLLKLETNE-FQQLQSKISLIS-----EKLESTESILQEATSSMS 115
V Q +K + + Q + ++LE E ++L K+S+ S E L E +E +
Sbjct: 1022 VEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAG-- 1079
Query: 116 LMTQFEQEVSNLQDIMHDIQNNEEVLT------QRMQSLNEKFQNITDFWKRSLEEMNIN 169
T +EV L+ H ++ +E+ T ++ +S+ + + I +RS+E+
Sbjct: 1080 --TSGSEEVKVLE---HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENK 1134
Query: 170 TDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEE 229
+ E+ Q+ S+EQE++ L KD+E N+R + E +L + E
Sbjct: 1135 WKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIE-----NLRREREHLEMELEKAEM 1189
Query: 230 QLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAI------HSV 283
+ + + +L+ + + + N+ + + + L I+S I +V
Sbjct: 1190 ERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTV 1249
Query: 284 LRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQY 330
+ S ETE ++ N L+ + + + Q T E Y
Sbjct: 1250 IENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHY 1296
Score = 36.6 bits (83), Expect = 0.038
Identities = 51/341 (14%), Positives = 141/341 (41%), Gaps = 68/341 (19%)
Query: 62 VFQQSEKFAKVENQYQ----LLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLM 117
V Q + K A +Q++ +LK + NE ++L++ + L S +LQ+ L
Sbjct: 914 VAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKL- 972
Query: 118 TQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFW-------------KRSLE 164
F+ ++ L+ + ++ + ++ ++E+ + I+ W ++
Sbjct: 973 --FKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNN 1030
Query: 165 EMNINTDIFKSEAKHIHSQVTVQIN-------------------------SAEQEIKLLT 199
E + + EAK + ++ +++ S +E+K+L
Sbjct: 1031 ERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLE 1090
Query: 200 ERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKL 259
+LK+ ++ + + ++ ++ + +L ++T+ I L++ Q ++ + K+
Sbjct: 1091 HKLKEADE--MHTLLQLECEKYKSVL-------AETEGI--LQKLQRSVEQEENKWKVKV 1139
Query: 260 SDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIM 319
+ +++ ++ + E + + ++D+ ++ E L M++ E + V+E+
Sbjct: 1140 DESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVR 1199
Query: 320 EMQKTL------------EGIQYDNSILKMQNELDILKEKV 348
E++ L E + + K Q L++++ K+
Sbjct: 1200 ELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1240
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 63.5 bits (153), Expect = 3e-10
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 34/294 (11%)
Query: 83 TNEFQQLQSKISLISEKLES-----------TESILQEATSSMSLMTQFEQEVSNLQDIM 131
T QLQ K L++ E T+ ++ E S ++T+ + + L+
Sbjct: 328 TTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEH 387
Query: 132 HDIQNNEEVLTQRMQSLNEKFQNITDFWKRSL----EEMNINTDIFKSEAKHIHSQVTVQ 187
+ QN V Q Q + KFQ + + + + +E I D + + S+ + +
Sbjct: 388 NVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAE 447
Query: 188 INSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHA 247
+N Q+ L L + +T K Q+EE + EQ + K +L+E +
Sbjct: 448 LNKLRQDYARLVNELTE---------KTGKLQQEEVQKKNAEQAATQLKV--QLQEAERR 496
Query: 248 LFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMF-- 305
+ + +++E ++ ++ E+ + S+ D + +++++E MQ+
Sbjct: 497 WEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMES 556
Query: 306 -----NMEDDMLKAVSEIMEMQKTLEG-IQYDNSILKMQNELDILKEKVHDFIA 353
N E+ + V +I+E + L+ IQ +S + Q +L E++H IA
Sbjct: 557 EQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIA 610
Score = 54.3 bits (129), Expect = 2e-07
Identities = 74/344 (21%), Positives = 155/344 (45%), Gaps = 58/344 (16%)
Query: 75 QYQLLKLETNEFQQ---LQSKISLISEKLEST--ESILQEATSSMSLMTQFEQEVSNLQD 129
Q + LK + +F Q+ S+++E+L E Q + SL ++ ++ S ++
Sbjct: 577 QNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 636
Query: 130 IMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQIN 189
+ DIQN +L +Q L + N LE+M + + + + + Q+ +I+
Sbjct: 637 LK-DIQNMNFLLKAEVQKL-QALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEIS 694
Query: 190 SAEQEIKLLTERLKDLEDSTLRNIRTVK----------------RQEEEDLLRVEEQLGS 233
+ +E K+L ++ K L+ S ++ ++T+ ++++E L VEE L +
Sbjct: 695 NKMEEFKILNDQNKALK-SEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLET 753
Query: 234 DTKAIEKLEEEQHALFARDEDLTNKLSDYEPK----------VEECKTHLPTIESAIHSV 283
+ EEE +A+ + LT ++ D + K VEE K + + I SV
Sbjct: 754 GLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSV 813
Query: 284 LRVSQ----DLIETEKKMEDLTMQMFNMEDDM----------LKAVSEIMEMQKTLEGIQ 329
+ + + EK ++DL ++ +++++ L S++ E+Q L+G +
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Query: 330 YDNSILKMQNELDILKEKVHDFIAYSSTGEKGTLKEYNIENKGI 373
+ +K +L+EK D ++TG+ L++ EN+ +
Sbjct: 874 EQMNTMKA-----VLEEKEKDL---ANTGK--WLQDLQEENESL 907
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/281 (17%), Positives = 121/281 (43%), Gaps = 14/281 (4%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLM-TQFEQE 123
+ E+ ++N LLK E + Q L ++ + + +LE + + + L+ Q + E
Sbjct: 633 KEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 692
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSL-----NEKFQNITDFWKRSLEEMNINTDIFKSEAK 178
+SN + + + + L +Q L + +++ + ++ ++E + + +
Sbjct: 693 ISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLE 752
Query: 179 HIHSQVTV---QINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDT 235
QV ++N+ E LT+ ++DL+ +N + E+L +V +
Sbjct: 753 TGLIQVATKEEELNAIRTENSSLTKEVQDLK--AKQNDQVSFASLVEELKKVIHEKDGKI 810
Query: 236 KAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEK 295
K++E+L E + A E + D + +++ K + ++ L ++ + E +
Sbjct: 811 KSVEELLEAELLKVANKE---KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQN 867
Query: 296 KMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILK 336
++ QM M+ + + ++ K L+ +Q +N LK
Sbjct: 868 LLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Score = 46.2 bits (108), Expect = 5e-05
Identities = 61/301 (20%), Positives = 134/301 (44%), Gaps = 36/301 (11%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN 126
EK K++ +LL+ + + +++ I + S +Q+ + + F V
Sbjct: 739 EKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEE 798
Query: 127 LQDIMHD----IQNNEEVLTQRMQSLNEKFQNITDFWK--RSLEEMNINTDIFKSEAKHI 180
L+ ++H+ I++ EE+L + + K + + D + ++L+E N + K++ I
Sbjct: 799 LKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSI 858
Query: 181 HSQVTVQIN---SAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKA 237
S+V N E+++ + L++ E + ++ +EE E L + +
Sbjct: 859 TSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEE-----NESLKAHVQE 913
Query: 238 IEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEK-- 295
+ + ++ + ++ E+L L + E +++ + L ES + S ++ QD+ + K
Sbjct: 914 VAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLF 973
Query: 296 --KMEDLTMQ------MFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEK 347
++E L Q F +++LK +S E +K + G + NELD LK+
Sbjct: 974 KSQIEQLKQQNYQQASSFPPHEELLKVIS---EREKEISG---------LWNELDSLKDA 1021
Query: 348 V 348
V
Sbjct: 1022 V 1022
Score = 42.7 bits (99), Expect = 5e-04
Identities = 51/268 (19%), Positives = 112/268 (41%), Gaps = 10/268 (3%)
Query: 71 KVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDI 130
K+ YQ + +FQQ++ ++ L+ IL++A S+ + + +Q + L +
Sbjct: 393 KIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQS-AELNKL 451
Query: 131 MHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINS 190
D LT++ L ++ + K++ E+ + EA+ +V I
Sbjct: 452 RQDYARLVNELTEKTGKLQQE-----EVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 506
Query: 191 AEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFA 250
E + + L+ + ++++ + D L ++QL + + ++ +E EQ +
Sbjct: 507 RTAEHEAAQQDLQSKFVAKENEVQSL-HSKLTDTLVSKQQL--EQRLMQLMESEQKRV-N 562
Query: 251 RDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDD 310
++E L ++ D + E K + S I + S E K + + Q+ ED
Sbjct: 563 KEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDS 622
Query: 311 MLKAVSEIMEMQKTLEGIQYDNSILKMQ 338
+ + ++ L+ IQ N +LK +
Sbjct: 623 LASERDRLTSKEEELKDIQNMNFLLKAE 650
Score = 40.8 bits (94), Expect = 0.002
Identities = 60/303 (19%), Positives = 133/303 (43%), Gaps = 52/303 (17%)
Query: 73 ENQYQLLKLETNE-FQQLQSKISLIS-----EKLESTESILQEATSSMSLMTQFEQEVSN 126
+ Q + ++LE E ++L K+S+ S E L E +E + T +EV
Sbjct: 1062 QQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAG----TSGSEEVKV 1117
Query: 127 LQDIMHDIQNNEEVLT------QRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
L+ H ++ +E+ T ++ +S+ + + I +RS+E+ + E+
Sbjct: 1118 LE---HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKT 1174
Query: 181 HSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK 240
Q+ S+EQE++ L KD+E N+R E + L +E +EK
Sbjct: 1175 IKQMQSSFTSSEQELERLRSENKDIE-----NLR-----REREHLEME---------LEK 1215
Query: 241 LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDL 300
E E+ +L + L++ + K+++ + +R +++L + ++ +
Sbjct: 1216 AEMERSTYVTEVRELKDLLTELQKKLDD----------SYSEAVRQNEELNLLKAQLNET 1265
Query: 301 TMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEK 360
++ +++ K ++ + Q++LE IQ + I+K + +++ D + + EK
Sbjct: 1266 LTKLRTEQNERQKVAGDLHKAQQSLELIQ--SKIVKAAGDTTVIENS--DVSPETESSEK 1321
Query: 361 GTL 363
T+
Sbjct: 1322 ETM 1324
Score = 35.0 bits (79), Expect = 0.11
Identities = 57/362 (15%), Positives = 153/362 (42%), Gaps = 84/362 (23%)
Query: 62 VFQQSEKFAKVENQYQ----LLKLETNEFQQLQSKISLISEKLESTESILQEATSS---- 113
V Q + K A +Q++ +LK + NE ++L++ + L S +LQ+
Sbjct: 914 VAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLF 973
Query: 114 ------------------------MSLMTQFEQEVSNLQDIMHDI---------QNNE-- 138
+ ++++ E+E+S L + + + +NN+
Sbjct: 974 KSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLR 1033
Query: 139 EVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQIN--------- 189
E + M++L + + D ++ +E + + EAK + ++ +++
Sbjct: 1034 EKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGE 1093
Query: 190 ----------------SAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGS 233
S +E+K+L +LK+ ++ + + ++ ++ + +L +
Sbjct: 1094 WLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADE--MHTLLQLECEKYKSVL-------A 1144
Query: 234 DTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIET 293
+T+ I L++ Q ++ + K+ + +++ ++ + E + + ++D+
Sbjct: 1145 ETEGI--LQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENL 1202
Query: 294 EKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQ--YDNS---ILKMQNELDILKEKV 348
++ E L M++ E + V+E+ E++ L +Q D+S ++ EL++LK ++
Sbjct: 1203 RREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQL 1262
Query: 349 HD 350
++
Sbjct: 1263 NE 1264
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 62.0 bits (149), Expect = 8e-10
Identities = 51/263 (19%), Positives = 118/263 (44%), Gaps = 31/263 (11%)
Query: 80 KLETNEFQ---QLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN-LQDIMHDIQ 135
K ET+ Q +L+ ++++L+ E ++ + S + + + + N ++D+M D++
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433
Query: 136 NNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEI 195
+ + F I WK+ EE + + EA+ + +++
Sbjct: 1434 RSNAAAAA-LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELF---------- 1482
Query: 196 KLLTERLKDLEDSTLRNIRTVKRQE---EEDLLRVEEQLGSDTKAIEKLEEEQHALFARD 252
+LK+ + +L ++ T KR+ +E++ + EQLGS K I +LE+ + L A
Sbjct: 1483 -----KLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 1537
Query: 253 EDLTNKLSDYEPKVEECKTHLPTIESAIHSV-LRVSQDLIETEKKMEDLTMQMFNMEDDM 311
+L + L + E +E + + + + + + + L E +++ME + D +
Sbjct: 1538 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSL 1597
Query: 312 -------LKAVSEIMEMQKTLEG 327
++ +E + ++K +EG
Sbjct: 1598 QTSLDAETRSRNEALRVKKKMEG 1620
Score = 49.3 bits (116), Expect = 6e-06
Identities = 65/307 (21%), Positives = 143/307 (46%), Gaps = 35/307 (11%)
Query: 60 WFVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQ 119
+F + K A+ E + +K E ++ K ++LE L + + + L Q
Sbjct: 833 YFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQ 892
Query: 120 FEQE-VSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDF------WKRSLEE--MNINT 170
EQ+ +++ ++ + N+ L +++ +NE+ ++ + KR LE+ +
Sbjct: 893 AEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKR 952
Query: 171 DIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEE------EDL 224
DI + + ++V + ++ E ++K LTE + L++ + + K +E +DL
Sbjct: 953 DI--DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1010
Query: 225 LRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVL 284
E+++ + TKA KLE++ +DL L + E KV + L + + L
Sbjct: 1011 QAEEDKVNTLTKAKVKLEQQV-------DDLEGSL-EQEKKV---RMDLERAKRKLEGDL 1059
Query: 285 RVSQDLI---ETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNEL 341
+++Q+ I E +K+ D + +D L A++ +E ++ L G Q + ++Q +
Sbjct: 1060 KLTQESIMDLENDKQQLD---ERLKKKDFELNALNARIEDEQAL-GSQLQKKLKELQARI 1115
Query: 342 DILKEKV 348
+ L+E++
Sbjct: 1116 EELEEEL 1122
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/298 (19%), Positives = 124/298 (41%), Gaps = 38/298 (12%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISL-ISEKLESTES-------ILQEATSSMSLMT 118
E A +E++ + EF Q++++I ++EK E E ++ +S+ T
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAET 1605
Query: 119 QFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAK 178
+ E ++ M N E+ + + Q +SL+ + +T I +A
Sbjct: 1606 RSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV----KSLQSLLKDTQIQLDDA- 1660
Query: 179 HIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAI 238
V+ N +E + ER +L + L +R V Q E E++L ++ +
Sbjct: 1661 -------VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1713
Query: 239 EKLEEEQHALFAR----DEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETE 294
+ L + +L + D DL+ ++ E V+EC+ + AI ++++L
Sbjct: 1714 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEEL---- 1769
Query: 295 KKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGI----------QYDNSILKMQNELD 342
KK +D + + M+ +M + + ++ E I + + + +++NEL+
Sbjct: 1770 KKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1827
Score = 45.8 bits (107), Expect = 6e-05
Identities = 45/237 (18%), Positives = 109/237 (45%), Gaps = 20/237 (8%)
Query: 117 MTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSE 176
M ++E + L++ + + + L ++M SL ++ ++ + E+ N+ ++
Sbjct: 849 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ--LQVQAEQDNL------AD 900
Query: 177 AKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTK 236
A+ Q+ E ++K + ERL+D E+ + KR+ E++ ++ +
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKRDIDDLEL 959
Query: 237 AIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKK 296
+ K+E+E+HA + ++LT +++ + + + ++ A L DL E K
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL---DDLQAEEDK 1016
Query: 297 MEDLTMQMFNME---DDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHD 350
+ LT +E DD+ ++ + +++ LE + K++ +L + +E + D
Sbjct: 1017 VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLE-----RAKRKLEGDLKLTQESIMD 1068
Score = 41.2 bits (95), Expect = 0.002
Identities = 52/288 (18%), Positives = 124/288 (43%), Gaps = 34/288 (11%)
Query: 63 FQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQ 122
F+ + A++E++ L + ++LQ++I + E+LE+ + + L + +
Sbjct: 1085 FELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVE---KLRSDLSR 1141
Query: 123 EVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHS 182
E+ + + + + V + + +FQ + +R LEE + + + + H+
Sbjct: 1142 ELEEISERLEEAGGATSVQIEMNKKREAEFQKM----RRDLEEATLQHEATAAALRKKHA 1197
Query: 183 QVTVQINSAEQEIKLLTERLK--------DLED--STLRNIRTVKRQEEEDLLRVEEQLG 232
++ ++ + ++L+ +L+D S + I K E+ +E+Q+
Sbjct: 1198 DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMN 1257
Query: 233 SDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIE 292
K EE Q ++ DLT++ + + + E L E+ I + R +
Sbjct: 1258 EHR---SKAEETQRSV----NDLTSQRAKLQTENGELSRQLDEKEALISQLTR---GKLT 1307
Query: 293 TEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNE 340
+++EDL Q+ ++ +KA + + L+ ++D +L+ Q E
Sbjct: 1308 YTQQLEDLKRQL----EEEVKAKNALAH---ALQSARHDCDLLREQYE 1348
Score = 37.0 bits (84), Expect = 0.029
Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 24/177 (13%)
Query: 85 EFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQ----NNEEV 140
+ QLQ+++ ++ + E ++A + ++M + E+ QD ++ N E+
Sbjct: 1733 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAE---ELKKEQDTSAHLERMKKNMEQT 1789
Query: 141 LTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSE--AKHIHSQVTVQ-INSAEQEIKL 197
+ L+E Q K+ L+++ ++E A+ + +V+ + +E+ IK
Sbjct: 1790 IKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKE 1849
Query: 198 LTE----------RLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEE 244
LT RL+DL D ++ KRQ EE EEQ ++ K++ E
Sbjct: 1850 LTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE----AEEQANTNLSKFRKVQHE 1902
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 60.8 bits (146), Expect = 2e-09
Identities = 73/342 (21%), Positives = 149/342 (43%), Gaps = 62/342 (18%)
Query: 69 FAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMT---------- 118
F KV+ Q+ + E E Q + ++ E+ + E+ L+E S +T
Sbjct: 838 FTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896
Query: 119 QFEQEV---------------SNLQDIMHDIQ---NNEEVLTQRMQSLNEKF-QNITDFW 159
Q E E+ L++I+H+++ EE Q++Q+ +K Q + D
Sbjct: 897 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE 956
Query: 160 KRSLEE------MNINTDIFKSEAKHIHSQVTV---QINSAEQEIKLLTERLKDL----- 205
++ EE + + +++ K + ++ V Q N +E KLL ER+ DL
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Query: 206 -EDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEP 264
E+ +N+ +K + E + +E +L + K+ ++LE+ + L D +++D +
Sbjct: 1017 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQA 1076
Query: 265 KVEECKTHLPTIESAIHSVLRVSQDLIETE----KKMEDLTMQMFNMEDDM--LKAVSEI 318
++ E K L E + + L D I + KK+ +L + ++++D+ +A
Sbjct: 1077 QIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1136
Query: 319 MEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEK 360
E QK + EL+ LK ++ D + ++T ++
Sbjct: 1137 AEKQKR-----------DLGEELEALKTELEDTLDSTATQQE 1167
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/320 (16%), Positives = 146/320 (45%), Gaps = 56/320 (17%)
Query: 68 KFAKVENQYQLLKLETNEFQ----QLQSKISLISEKLESTESILQEATSSMSLMTQFEQE 123
K K+E Q Q L+ + ++ + +L K+ + ++ES +L EA + ++
Sbjct: 1253 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKA---IKLAKD 1309
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQ 183
V++L + D Q + T++ +++ K + + + ++++ + ++ +HI S
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI-ST 1368
Query: 184 VTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEE 243
+ +Q++ ++++++ ++ LE+ K++ ++++ + +Q A +KLE+
Sbjct: 1369 LNIQLSDSKKKLQDFASTVEALEEG--------KKRFQKEIENLTQQYEEKAAAYDKLEK 1420
Query: 244 EQH-------------------------------ALFARDEDLTNKLSDYEPKVE----E 268
++ L A ++++++K +D + E E
Sbjct: 1421 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1480
Query: 269 CKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGI 328
+T ++ A+ L ++L T K ++ + + +DD+ K V E+ + ++ LE
Sbjct: 1481 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE-- 1538
Query: 329 QYDNSILKMQNELDILKEKV 348
+ +M+ +L+ L++++
Sbjct: 1539 ---TQMEEMKTQLEELEDEL 1555
Score = 48.5 bits (114), Expect = 1e-05
Identities = 55/304 (18%), Positives = 121/304 (39%), Gaps = 35/304 (11%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEV 124
Q E AK E + +LK +E + +S + + E + ++E T + QF++
Sbjct: 1165 QQELRAKREQEVTVLKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLE---QFKRAK 1219
Query: 125 SNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQV 184
+NL ++ L ++ L + Q + + K+ LE S+ + +++
Sbjct: 1220 ANLDKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 185 TVQINSAEQEIKLLTERLKDLEDSTLR---------------------------NIRTVK 217
+++ + E++ +T L + E ++ N+ T
Sbjct: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
Query: 218 RQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIE 277
RQ EE+ +++QL + +A + LE L + D KL D+ VE + +
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
Query: 278 SAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQ--YDNSIL 335
I ++ + ++ K+E ++ DD++ + ++ LE Q +D +
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 336 KMQN 339
+ +N
Sbjct: 1459 EEKN 1462
Score = 45.4 bits (106), Expect = 8e-05
Identities = 36/185 (19%), Positives = 93/185 (50%), Gaps = 6/185 (3%)
Query: 187 QINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQH 246
++ + E E++ ER + E+ L+ + Q E+ ++EQL ++T+ + EE +
Sbjct: 853 EMQAKEDELQKTKERQQKAENE-LKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 911
Query: 247 ALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFN 306
L A+ ++L L + E ++EE + +++ +++Q +++ E+++E+
Sbjct: 912 RLAAKKQELEEILHEMEARLEEEEDRGQQLQA---ERKKMAQQMLDLEEQLEEEEAARQK 968
Query: 307 MEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEKGTLKEY 366
++ + + A ++I +++ E + D+ K+ E +L+E++ D + E+
Sbjct: 969 LQLEKVTAEAKIKKLED--EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 367 NIENK 371
++NK
Sbjct: 1027 KLKNK 1031
Score = 45.1 bits (105), Expect = 1e-04
Identities = 70/323 (21%), Positives = 139/323 (43%), Gaps = 50/323 (15%)
Query: 66 SEKFAKVENQYQLLKLETNEF----QQLQSKISLISEKLESTESILQEATSSMSLMTQ-- 119
S K ++E + L+ + +E Q L+ IS ++ +L ++ LQ+ S++ + +
Sbjct: 1335 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1394
Query: 120 --FEQEVSNLQDIMHD-------IQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINT 170
F++E+ NL + ++ + L Q + L N +LE+
Sbjct: 1395 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS-NLEKKQRKF 1453
Query: 171 DIFKSEAKHIHSQVTVQINSAEQEIK-----------LLTERLKDLEDSTLRNIRTVKRQ 219
D +E K+I S+ + + AE E + L E L+ E+ L + +
Sbjct: 1454 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE--LERTNKMLKA 1511
Query: 220 EEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKV---EECKTHLPTI 276
E EDL+ ++ +G K + +LE+ + AL + E++ +L + E ++ E+ K L
Sbjct: 1512 EMEDLVSSKDDVG---KNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 277 ESAIHSVLRVSQDL----IETEKKMEDLTMQMFNME---DDMLKAVSEIMEMQKTLEG-- 327
A+ + +DL + E+K L Q+ E +D K + +K LEG
Sbjct: 1569 MQALKG--QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1626
Query: 328 ----IQYDNSILKMQNELDILKE 346
+Q D++I + + L++
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRK 1649
Score = 36.2 bits (82), Expect = 0.050
Identities = 39/237 (16%), Positives = 99/237 (41%), Gaps = 20/237 (8%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLISEKLEST----ESILQEATSSMSLMTQFEQEVSNLQ 128
EN+ + LE + QLQ ++ + E + +E SS+S + E L+
Sbjct: 1677 ENEKKAKSLEA-DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1735
Query: 129 DIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQI 188
+ ++ E M++++++ + T + E+++ +S A+ S
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKAT----QQAEQLSNELATERSTAQKNESAR---- 1787
Query: 189 NSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSD-------TKAIEKL 241
E++ K L +L ++E + ++ E + ++EEQ+ + TK++++
Sbjct: 1788 QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK 1847
Query: 242 EEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKME 298
+++ + + ED Y+ + E+ + ++ + SQ + +K++
Sbjct: 1848 DKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1904
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 60.8 bits (146), Expect = 2e-09
Identities = 73/342 (21%), Positives = 149/342 (43%), Gaps = 62/342 (18%)
Query: 69 FAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMT---------- 118
F KV+ Q+ + E E Q + ++ E+ + E+ L+E S +T
Sbjct: 845 FTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 903
Query: 119 QFEQEV---------------SNLQDIMHDIQ---NNEEVLTQRMQSLNEKF-QNITDFW 159
Q E E+ L++I+H+++ EE Q++Q+ +K Q + D
Sbjct: 904 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE 963
Query: 160 KRSLEE------MNINTDIFKSEAKHIHSQVTV---QINSAEQEIKLLTERLKDL----- 205
++ EE + + +++ K + ++ V Q N +E KLL ER+ DL
Sbjct: 964 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Query: 206 -EDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEP 264
E+ +N+ +K + E + +E +L + K+ ++LE+ + L D +++D +
Sbjct: 1024 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQA 1083
Query: 265 KVEECKTHLPTIESAIHSVLRVSQDLIETE----KKMEDLTMQMFNMEDDM--LKAVSEI 318
++ E K L E + + L D I + KK+ +L + ++++D+ +A
Sbjct: 1084 QIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1143
Query: 319 MEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEK 360
E QK + EL+ LK ++ D + ++T ++
Sbjct: 1144 AEKQKR-----------DLGEELEALKTELEDTLDSTATQQE 1174
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/320 (16%), Positives = 146/320 (45%), Gaps = 56/320 (17%)
Query: 68 KFAKVENQYQLLKLETNEFQ----QLQSKISLISEKLESTESILQEATSSMSLMTQFEQE 123
K K+E Q Q L+ + ++ + +L K+ + ++ES +L EA + ++
Sbjct: 1260 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKA---IKLAKD 1316
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQ 183
V++L + D Q + T++ +++ K + + + ++++ + ++ +HI S
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI-ST 1375
Query: 184 VTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEE 243
+ +Q++ ++++++ ++ LE+ K++ ++++ + +Q A +KLE+
Sbjct: 1376 LNIQLSDSKKKLQDFASTVEALEEG--------KKRFQKEIENLTQQYEEKAAAYDKLEK 1427
Query: 244 EQH-------------------------------ALFARDEDLTNKLSDYEPKVE----E 268
++ L A ++++++K +D + E E
Sbjct: 1428 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1487
Query: 269 CKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGI 328
+T ++ A+ L ++L T K ++ + + +DD+ K V E+ + ++ LE
Sbjct: 1488 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE-- 1545
Query: 329 QYDNSILKMQNELDILKEKV 348
+ +M+ +L+ L++++
Sbjct: 1546 ---TQMEEMKTQLEELEDEL 1562
Score = 48.5 bits (114), Expect = 1e-05
Identities = 55/304 (18%), Positives = 121/304 (39%), Gaps = 35/304 (11%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEV 124
Q E AK E + +LK +E + +S + + E + ++E T + QF++
Sbjct: 1172 QQELRAKREQEVTVLKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLE---QFKRAK 1226
Query: 125 SNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQV 184
+NL ++ L ++ L + Q + + K+ LE S+ + +++
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEAQVQELQSKCSDGERARAEL 1285
Query: 185 TVQINSAEQEIKLLTERLKDLEDSTLR---------------------------NIRTVK 217
+++ + E++ +T L + E ++ N+ T
Sbjct: 1286 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1345
Query: 218 RQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIE 277
RQ EE+ +++QL + +A + LE L + D KL D+ VE + +
Sbjct: 1346 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1405
Query: 278 SAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQ--YDNSIL 335
I ++ + ++ K+E ++ DD++ + ++ LE Q +D +
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 336 KMQN 339
+ +N
Sbjct: 1466 EEKN 1469
Score = 45.4 bits (106), Expect = 8e-05
Identities = 36/185 (19%), Positives = 93/185 (50%), Gaps = 6/185 (3%)
Query: 187 QINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQH 246
++ + E E++ ER + E+ L+ + Q E+ ++EQL ++T+ + EE +
Sbjct: 860 EMQAKEDELQKTKERQQKAENE-LKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 918
Query: 247 ALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFN 306
L A+ ++L L + E ++EE + +++ +++Q +++ E+++E+
Sbjct: 919 RLAAKKQELEEILHEMEARLEEEEDRGQQLQA---ERKKMAQQMLDLEEQLEEEEAARQK 975
Query: 307 MEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEKGTLKEY 366
++ + + A ++I +++ E + D+ K+ E +L+E++ D + E+
Sbjct: 976 LQLEKVTAEAKIKKLED--EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 367 NIENK 371
++NK
Sbjct: 1034 KLKNK 1038
Score = 45.1 bits (105), Expect = 1e-04
Identities = 70/323 (21%), Positives = 139/323 (43%), Gaps = 50/323 (15%)
Query: 66 SEKFAKVENQYQLLKLETNEF----QQLQSKISLISEKLESTESILQEATSSMSLMTQ-- 119
S K ++E + L+ + +E Q L+ IS ++ +L ++ LQ+ S++ + +
Sbjct: 1342 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1401
Query: 120 --FEQEVSNLQDIMHD-------IQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINT 170
F++E+ NL + ++ + L Q + L N +LE+
Sbjct: 1402 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS-NLEKKQRKF 1460
Query: 171 DIFKSEAKHIHSQVTVQINSAEQEIK-----------LLTERLKDLEDSTLRNIRTVKRQ 219
D +E K+I S+ + + AE E + L E L+ E+ L + +
Sbjct: 1461 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE--LERTNKMLKA 1518
Query: 220 EEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKV---EECKTHLPTI 276
E EDL+ ++ +G K + +LE+ + AL + E++ +L + E ++ E+ K L
Sbjct: 1519 EMEDLVSSKDDVG---KNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 277 ESAIHSVLRVSQDL----IETEKKMEDLTMQMFNME---DDMLKAVSEIMEMQKTLEG-- 327
A+ + +DL + E+K L Q+ E +D K + +K LEG
Sbjct: 1576 MQALKG--QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1633
Query: 328 ----IQYDNSILKMQNELDILKE 346
+Q D++I + + L++
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRK 1656
Score = 36.2 bits (82), Expect = 0.050
Identities = 39/237 (16%), Positives = 99/237 (41%), Gaps = 20/237 (8%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLISEKLEST----ESILQEATSSMSLMTQFEQEVSNLQ 128
EN+ + LE + QLQ ++ + E + +E SS+S + E L+
Sbjct: 1684 ENEKKAKSLEA-DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1742
Query: 129 DIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQI 188
+ ++ E M++++++ + T + E+++ +S A+ S
Sbjct: 1743 ARIAQLEEELEEEQGNMEAMSDRVRKAT----QQAEQLSNELATERSTAQKNESAR---- 1794
Query: 189 NSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSD-------TKAIEKL 241
E++ K L +L ++E + ++ E + ++EEQ+ + TK++++
Sbjct: 1795 QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK 1854
Query: 242 EEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKME 298
+++ + + ED Y+ + E+ + ++ + SQ + +K++
Sbjct: 1855 DKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1911
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 60.8 bits (146), Expect = 2e-09
Identities = 73/342 (21%), Positives = 149/342 (43%), Gaps = 62/342 (18%)
Query: 69 FAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMT---------- 118
F KV+ Q+ + E E Q + ++ E+ + E+ L+E S +T
Sbjct: 845 FTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 903
Query: 119 QFEQEV---------------SNLQDIMHDIQ---NNEEVLTQRMQSLNEKF-QNITDFW 159
Q E E+ L++I+H+++ EE Q++Q+ +K Q + D
Sbjct: 904 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE 963
Query: 160 KRSLEE------MNINTDIFKSEAKHIHSQVTV---QINSAEQEIKLLTERLKDL----- 205
++ EE + + +++ K + ++ V Q N +E KLL ER+ DL
Sbjct: 964 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Query: 206 -EDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEP 264
E+ +N+ +K + E + +E +L + K+ ++LE+ + L D +++D +
Sbjct: 1024 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQA 1083
Query: 265 KVEECKTHLPTIESAIHSVLRVSQDLIETE----KKMEDLTMQMFNMEDDM--LKAVSEI 318
++ E K L E + + L D I + KK+ +L + ++++D+ +A
Sbjct: 1084 QIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1143
Query: 319 MEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEK 360
E QK + EL+ LK ++ D + ++T ++
Sbjct: 1144 AEKQKR-----------DLGEELEALKTELEDTLDSTATQQE 1174
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/320 (16%), Positives = 146/320 (45%), Gaps = 56/320 (17%)
Query: 68 KFAKVENQYQLLKLETNEFQ----QLQSKISLISEKLESTESILQEATSSMSLMTQFEQE 123
K K+E Q Q L+ + ++ + +L K+ + ++ES +L EA + ++
Sbjct: 1260 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKA---IKLAKD 1316
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQ 183
V++L + D Q + T++ +++ K + + + ++++ + ++ +HI S
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI-ST 1375
Query: 184 VTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEE 243
+ +Q++ ++++++ ++ LE+ K++ ++++ + +Q A +KLE+
Sbjct: 1376 LNIQLSDSKKKLQDFASTVEALEEG--------KKRFQKEIENLTQQYEEKAAAYDKLEK 1427
Query: 244 EQH-------------------------------ALFARDEDLTNKLSDYEPKVE----E 268
++ L A ++++++K +D + E E
Sbjct: 1428 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1487
Query: 269 CKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGI 328
+T ++ A+ L ++L T K ++ + + +DD+ K V E+ + ++ LE
Sbjct: 1488 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE-- 1545
Query: 329 QYDNSILKMQNELDILKEKV 348
+ +M+ +L+ L++++
Sbjct: 1546 ---TQMEEMKTQLEELEDEL 1562
Score = 48.5 bits (114), Expect = 1e-05
Identities = 55/304 (18%), Positives = 121/304 (39%), Gaps = 35/304 (11%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEV 124
Q E AK E + +LK +E + +S + + E + ++E T + QF++
Sbjct: 1172 QQELRAKREQEVTVLKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLE---QFKRAK 1226
Query: 125 SNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQV 184
+NL ++ L ++ L + Q + + K+ LE S+ + +++
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEAQVQELQSKCSDGERARAEL 1285
Query: 185 TVQINSAEQEIKLLTERLKDLEDSTLR---------------------------NIRTVK 217
+++ + E++ +T L + E ++ N+ T
Sbjct: 1286 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1345
Query: 218 RQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIE 277
RQ EE+ +++QL + +A + LE L + D KL D+ VE + +
Sbjct: 1346 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1405
Query: 278 SAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQ--YDNSIL 335
I ++ + ++ K+E ++ DD++ + ++ LE Q +D +
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 336 KMQN 339
+ +N
Sbjct: 1466 EEKN 1469
Score = 45.4 bits (106), Expect = 8e-05
Identities = 36/185 (19%), Positives = 93/185 (50%), Gaps = 6/185 (3%)
Query: 187 QINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQH 246
++ + E E++ ER + E+ L+ + Q E+ ++EQL ++T+ + EE +
Sbjct: 860 EMQAKEDELQKTKERQQKAENE-LKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 918
Query: 247 ALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFN 306
L A+ ++L L + E ++EE + +++ +++Q +++ E+++E+
Sbjct: 919 RLAAKKQELEEILHEMEARLEEEEDRGQQLQA---ERKKMAQQMLDLEEQLEEEEAARQK 975
Query: 307 MEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEKGTLKEY 366
++ + + A ++I +++ E + D+ K+ E +L+E++ D + E+
Sbjct: 976 LQLEKVTAEAKIKKLED--EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 367 NIENK 371
++NK
Sbjct: 1034 KLKNK 1038
Score = 45.1 bits (105), Expect = 1e-04
Identities = 70/323 (21%), Positives = 139/323 (43%), Gaps = 50/323 (15%)
Query: 66 SEKFAKVENQYQLLKLETNEF----QQLQSKISLISEKLESTESILQEATSSMSLMTQ-- 119
S K ++E + L+ + +E Q L+ IS ++ +L ++ LQ+ S++ + +
Sbjct: 1342 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1401
Query: 120 --FEQEVSNLQDIMHD-------IQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINT 170
F++E+ NL + ++ + L Q + L N +LE+
Sbjct: 1402 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS-NLEKKQRKF 1460
Query: 171 DIFKSEAKHIHSQVTVQINSAEQEIK-----------LLTERLKDLEDSTLRNIRTVKRQ 219
D +E K+I S+ + + AE E + L E L+ E+ L + +
Sbjct: 1461 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE--LERTNKMLKA 1518
Query: 220 EEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKV---EECKTHLPTI 276
E EDL+ ++ +G K + +LE+ + AL + E++ +L + E ++ E+ K L
Sbjct: 1519 EMEDLVSSKDDVG---KNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 277 ESAIHSVLRVSQDL----IETEKKMEDLTMQMFNME---DDMLKAVSEIMEMQKTLEG-- 327
A+ + +DL + E+K L Q+ E +D K + +K LEG
Sbjct: 1576 MQALKG--QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1633
Query: 328 ----IQYDNSILKMQNELDILKE 346
+Q D++I + + L++
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRK 1656
Score = 36.2 bits (82), Expect = 0.050
Identities = 39/237 (16%), Positives = 99/237 (41%), Gaps = 20/237 (8%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLISEKLEST----ESILQEATSSMSLMTQFEQEVSNLQ 128
EN+ + LE + QLQ ++ + E + +E SS+S + E L+
Sbjct: 1684 ENEKKAKSLEA-DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1742
Query: 129 DIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQI 188
+ ++ E M++++++ + T + E+++ +S A+ S
Sbjct: 1743 ARIAQLEEELEEEQGNMEAMSDRVRKAT----QQAEQLSNELATERSTAQKNESAR---- 1794
Query: 189 NSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSD-------TKAIEKL 241
E++ K L +L ++E + ++ E + ++EEQ+ + TK++++
Sbjct: 1795 QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK 1854
Query: 242 EEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKME 298
+++ + + ED Y+ + E+ + ++ + SQ + +K++
Sbjct: 1855 DKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1911
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 60.8 bits (146), Expect = 2e-09
Identities = 73/342 (21%), Positives = 149/342 (43%), Gaps = 62/342 (18%)
Query: 69 FAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMT---------- 118
F KV+ Q+ + E E Q + ++ E+ + E+ L+E S +T
Sbjct: 838 FTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896
Query: 119 QFEQEV---------------SNLQDIMHDIQ---NNEEVLTQRMQSLNEKF-QNITDFW 159
Q E E+ L++I+H+++ EE Q++Q+ +K Q + D
Sbjct: 897 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE 956
Query: 160 KRSLEE------MNINTDIFKSEAKHIHSQVTV---QINSAEQEIKLLTERLKDL----- 205
++ EE + + +++ K + ++ V Q N +E KLL ER+ DL
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Query: 206 -EDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEP 264
E+ +N+ +K + E + +E +L + K+ ++LE+ + L D +++D +
Sbjct: 1017 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQA 1076
Query: 265 KVEECKTHLPTIESAIHSVLRVSQDLIETE----KKMEDLTMQMFNMEDDM--LKAVSEI 318
++ E K L E + + L D I + KK+ +L + ++++D+ +A
Sbjct: 1077 QIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1136
Query: 319 MEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEK 360
E QK + EL+ LK ++ D + ++T ++
Sbjct: 1137 AEKQKR-----------DLGEELEALKTELEDTLDSTATQQE 1167
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/320 (16%), Positives = 146/320 (45%), Gaps = 56/320 (17%)
Query: 68 KFAKVENQYQLLKLETNEFQ----QLQSKISLISEKLESTESILQEATSSMSLMTQFEQE 123
K K+E Q Q L+ + ++ + +L K+ + ++ES +L EA + ++
Sbjct: 1253 KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKA---IKLAKD 1309
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQ 183
V++L + D Q + T++ +++ K + + + ++++ + ++ +HI S
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHI-ST 1368
Query: 184 VTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEE 243
+ +Q++ ++++++ ++ LE+ K++ ++++ + +Q A +KLE+
Sbjct: 1369 LNIQLSDSKKKLQDFASTVEALEEG--------KKRFQKEIENLTQQYEEKAAAYDKLEK 1420
Query: 244 EQH-------------------------------ALFARDEDLTNKLSDYEPKVE----E 268
++ L A ++++++K +D + E E
Sbjct: 1421 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1480
Query: 269 CKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGI 328
+T ++ A+ L ++L T K ++ + + +DD+ K V E+ + ++ LE
Sbjct: 1481 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE-- 1538
Query: 329 QYDNSILKMQNELDILKEKV 348
+ +M+ +L+ L++++
Sbjct: 1539 ---TQMEEMKTQLEELEDEL 1555
Score = 48.5 bits (114), Expect = 1e-05
Identities = 55/304 (18%), Positives = 121/304 (39%), Gaps = 35/304 (11%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEV 124
Q E AK E + +LK +E + +S + + E + ++E T + QF++
Sbjct: 1165 QQELRAKREQEVTVLKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLE---QFKRAK 1219
Query: 125 SNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQV 184
+NL ++ L ++ L + Q + + K+ LE S+ + +++
Sbjct: 1220 ANLDKNKQTLEKENADLAGELRVLGQAKQEV-EHKKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 185 TVQINSAEQEIKLLTERLKDLEDSTLR---------------------------NIRTVK 217
+++ + E++ +T L + E ++ N+ T
Sbjct: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
Query: 218 RQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIE 277
RQ EE+ +++QL + +A + LE L + D KL D+ VE + +
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
Query: 278 SAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQ--YDNSIL 335
I ++ + ++ K+E ++ DD++ + ++ LE Q +D +
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 336 KMQN 339
+ +N
Sbjct: 1459 EEKN 1462
Score = 45.4 bits (106), Expect = 8e-05
Identities = 36/185 (19%), Positives = 93/185 (50%), Gaps = 6/185 (3%)
Query: 187 QINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQH 246
++ + E E++ ER + E+ L+ + Q E+ ++EQL ++T+ + EE +
Sbjct: 853 EMQAKEDELQKTKERQQKAENE-LKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 911
Query: 247 ALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFN 306
L A+ ++L L + E ++EE + +++ +++Q +++ E+++E+
Sbjct: 912 RLAAKKQELEEILHEMEARLEEEEDRGQQLQA---ERKKMAQQMLDLEEQLEEEEAARQK 968
Query: 307 MEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEKGTLKEY 366
++ + + A ++I +++ E + D+ K+ E +L+E++ D + E+
Sbjct: 969 LQLEKVTAEAKIKKLED--EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 367 NIENK 371
++NK
Sbjct: 1027 KLKNK 1031
Score = 45.1 bits (105), Expect = 1e-04
Identities = 70/323 (21%), Positives = 139/323 (43%), Gaps = 50/323 (15%)
Query: 66 SEKFAKVENQYQLLKLETNEF----QQLQSKISLISEKLESTESILQEATSSMSLMTQ-- 119
S K ++E + L+ + +E Q L+ IS ++ +L ++ LQ+ S++ + +
Sbjct: 1335 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1394
Query: 120 --FEQEVSNLQDIMHD-------IQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINT 170
F++E+ NL + ++ + L Q + L N +LE+
Sbjct: 1395 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS-NLEKKQRKF 1453
Query: 171 DIFKSEAKHIHSQVTVQINSAEQEIK-----------LLTERLKDLEDSTLRNIRTVKRQ 219
D +E K+I S+ + + AE E + L E L+ E+ L + +
Sbjct: 1454 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE--LERTNKMLKA 1511
Query: 220 EEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKV---EECKTHLPTI 276
E EDL+ ++ +G K + +LE+ + AL + E++ +L + E ++ E+ K L
Sbjct: 1512 EMEDLVSSKDDVG---KNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 277 ESAIHSVLRVSQDL----IETEKKMEDLTMQMFNME---DDMLKAVSEIMEMQKTLEG-- 327
A+ + +DL + E+K L Q+ E +D K + +K LEG
Sbjct: 1569 MQALKG--QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1626
Query: 328 ----IQYDNSILKMQNELDILKE 346
+Q D++I + + L++
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRK 1649
Score = 36.2 bits (82), Expect = 0.050
Identities = 39/237 (16%), Positives = 99/237 (41%), Gaps = 20/237 (8%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLISEKLEST----ESILQEATSSMSLMTQFEQEVSNLQ 128
EN+ + LE + QLQ ++ + E + +E SS+S + E L+
Sbjct: 1677 ENEKKAKSLEA-DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1735
Query: 129 DIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQI 188
+ ++ E M++++++ + T + E+++ +S A+ S
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKAT----QQAEQLSNELATERSTAQKNESAR---- 1787
Query: 189 NSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSD-------TKAIEKL 241
E++ K L +L ++E + ++ E + ++EEQ+ + TK++++
Sbjct: 1788 QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK 1847
Query: 242 EEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKME 298
+++ + + ED Y+ + E+ + ++ + SQ + +K++
Sbjct: 1848 DKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1904
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 60.1 bits (144), Expect = 3e-09
Identities = 71/297 (23%), Positives = 130/297 (43%), Gaps = 35/297 (11%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKLEST----ESILQEATSSMSLMTQFEQ 122
E+ ++E + L+ + Q ++ + +LI+EKL+ T +++ QE L +
Sbjct: 884 ERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQI 943
Query: 123 EVSNLQDIMHDIQN----NEEVLTQRMQSLNEKFQNITDFWKRSLEEM--NINTDIFKSE 176
E L+ +HD N +E L ++SL + + I + EE+ N++ + E
Sbjct: 944 ERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGE 1003
Query: 177 AKHIHSQVTVQINSAE----QEIKLLTERLKDLE--DSTLRNIRTVKRQEE-----EDLL 225
K Q V I+ + + + LT +KD E + + ++ + E E ++
Sbjct: 1004 TKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVI 1063
Query: 226 RVEEQLGSDTKA-IEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVL 284
+EQL +D K IE E Q L L ++L + V + K H E +
Sbjct: 1064 AEKEQLKTDLKENIEMTIENQEELRL----LGDELKKQQEIVAQEKNHAIKKEGELS--- 1116
Query: 285 RVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNEL 341
R L E E+K+++ + Q+ + +L E+ EMQK + N I ++NEL
Sbjct: 1117 RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKI------NEIENLKNEL 1167
Score = 59.7 bits (143), Expect = 4e-09
Identities = 63/320 (19%), Positives = 149/320 (46%), Gaps = 41/320 (12%)
Query: 66 SEKFAKVENQYQLLKLETNEFQQLQSKISL----ISEKLESTESILQEATSSMSL---MT 118
+EKF + + + + L E + + ++ + + + E + T + +QE+ S M
Sbjct: 1334 NEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMK 1393
Query: 119 QFEQEVSNLQDIMHDIQNNEEVLTQ---RMQSLNEKFQNITDFWK---RSLEEMNINTDI 172
+ + E + + M + + L + M L+++ Q D K + +++ ++
Sbjct: 1394 EKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEV 1453
Query: 173 FKSEAKHIHS---QVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEE 229
+SE+ + ++ + E+E+K+ LK+ E+ T+ +R ++E ++ +++
Sbjct: 1454 LQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEE-TINELRVNLSEKETEISTIQK 1512
Query: 230 QLGSDTKAIEKLEEEQHALFARDEDLTNK-LSDYEPKVEECKT---HLPTIESAIHSVLR 285
QL + +KL+ + ++ ++E K +S+ + KV E K H +SA+ S+
Sbjct: 1513 QLEAIN---DKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSI-- 1567
Query: 286 VSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDIL- 344
E KM +LT ++ ++++ + E EM++ E +Q + LK +N +I+
Sbjct: 1568 --------ESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLK-ENTKEIVA 1618
Query: 345 -----KEKVHDFIAYSSTGE 359
+EK + F+ ++ E
Sbjct: 1619 KMKESQEKEYQFLKMTAVNE 1638
Score = 56.2 bits (134), Expect = 5e-08
Identities = 65/290 (22%), Positives = 133/290 (45%), Gaps = 31/290 (10%)
Query: 73 ENQYQLLKLET-NEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIM 131
E +YQ LK+ NE Q+ +I + E+ E+ + L+ + +TQ E NL+++
Sbjct: 1625 EKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHE--NLEEMR 1682
Query: 132 HDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEA-KHIHSQVTVQINS 190
+ ++ ++S+ E + D K +L E I D+ K E K +H + +
Sbjct: 1683 SVTKERDD-----LRSVEETLKVERDQLKENLRE-TITRDLEKQEELKIVHMHLKEHQET 1736
Query: 191 AEQEIKLLTERL-------KDLEDST-LRNIRTVKRQEEEDL--LRVEEQLGSDTKAIEK 240
++ +++E+ KDLE S + +K QEE + + ++EQ + K
Sbjct: 1737 IDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGI 1796
Query: 241 LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDL 300
+ E+ L +DL N + + K++E K + H ++ + +D+ ET+KK+ ++
Sbjct: 1797 VSEKTDKLSNMQKDLENSNAKLQEKIQELKANE-------HQLITLKKDVNETQKKVSEM 1849
Query: 301 TMQMFNMEDDMLK----AVSEIMEMQKTLEGIQYDNSILKMQNELDILKE 346
++D L + + QK E ++ S++K ++ L ++E
Sbjct: 1850 EQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEE 1899
Score = 55.8 bits (133), Expect = 6e-08
Identities = 63/303 (20%), Positives = 140/303 (46%), Gaps = 40/303 (13%)
Query: 66 SEKFAKVENQYQLLKLETN-EFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEV 124
S++ K ++ LK E + + Q+LQ K + E+L M Q ++++
Sbjct: 851 SKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNE--------------MEQLKEQL 896
Query: 125 SNLQDIMHDIQNNEEVLTQRMQSLNEKFQNIT---DFWKRSLEEMNINTDIFKSEAKHIH 181
N + ++ + ++T+++Q E+ + +T D K+ E + I D KS+ IH
Sbjct: 897 ENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSD---IH 953
Query: 182 SQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK- 240
V + I++ EQ ++ E LK ++ T+ +++ +E L +EE G ++
Sbjct: 954 DTVNMNIDTQEQ-LRNALESLKQHQE-TINTLKSKISEEVSRNLHMEENTGETKDEFQQK 1011
Query: 241 ---LEEEQHALFARDEDLT-----NKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIE 292
++++Q + LT N++ + + K+ ++ + SV+ ++ ++
Sbjct: 1012 MVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVI-AEKEQLK 1070
Query: 293 TEKKMEDLTMQMFNMED-----DMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEK 347
T+ K E++ M + N E+ D LK EI+ +K I+ + + + + L ++EK
Sbjct: 1071 TDLK-ENIEMTIENQEELRLLGDELKKQQEIVAQEKN-HAIKKEGELSRTCDRLAEVEEK 1128
Query: 348 VHD 350
+ +
Sbjct: 1129 LKE 1131
Score = 50.4 bits (119), Expect = 3e-06
Identities = 57/312 (18%), Positives = 131/312 (41%), Gaps = 30/312 (9%)
Query: 90 QSKISLISEKLESTESIL-QEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSL 148
Q ++ L+ ++L+ + I+ QE ++ + + L ++ ++ + L ++ Q L
Sbjct: 1084 QEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL 1143
Query: 149 NEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQ-----VTVQINSAEQEIKLLTER-- 201
+ +++ K+ E N+ ++ E H + + ++N +E+K +T+
Sbjct: 1144 LNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERK 1203
Query: 202 -LKDLEDST----------LRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEE---EQHA 247
LK+L+ S +R I Q +E+L L + I++L E+ A
Sbjct: 1204 VLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTA 1263
Query: 248 LFARDEDLTN---KLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQM 304
+DL KL + P + E + LP ++ + +++ + TE+ + +
Sbjct: 1264 QIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTL 1323
Query: 305 FNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNEL-----DILKEKVHDFIAYSSTGE 359
+E + L+ + E Q+ ++ + + LK E D LKE + + +A +
Sbjct: 1324 ARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQ 1383
Query: 360 KGTLKEYNIENK 371
+ N++ K
Sbjct: 1384 SKQEQSLNMKEK 1395
Score = 48.1 bits (113), Expect = 1e-05
Identities = 53/272 (19%), Positives = 121/272 (44%), Gaps = 29/272 (10%)
Query: 98 EKLESTESILQEATSSMSLMTQ-FEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNIT 156
E ++ I+ E T +S M + E + LQ+ + +++ NE L + +NE + ++
Sbjct: 1788 ETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVS 1847
Query: 157 DF--WKRSLEEMNINTDIFKSE----AKHIHSQVTVQ---------INSAEQEIKLLTER 201
+ K+ +++ ++ + E A+ +H + + E+ +KL ++
Sbjct: 1848 EMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQ 1907
Query: 202 LKD-LEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLS 260
LK+ L+++ R++ + + +L E + D K EK+ E+ + +DL
Sbjct: 1908 LKESLQETKARDLEIQQELKTARMLSKEHKETVD-KLREKISEKTIQISDIQKDLDKSKD 1966
Query: 261 DYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIME 320
+ + K++E ++ +LRV +D+ + KK+ ++ E L S M+
Sbjct: 1967 ELQKKIQE-------LQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMD 2019
Query: 321 ----MQKTLEGIQYDNSILKMQNELDILKEKV 348
+K E ++ + K ++EL +KE +
Sbjct: 2020 NFQLTKKLHESLEEIRIVAKERDELRRIKESL 2051
Score = 46.2 bits (108), Expect = 5e-05
Identities = 66/336 (19%), Positives = 140/336 (41%), Gaps = 43/336 (12%)
Query: 79 LKLETNEFQQLQSKISLISEKLE----STESILQEATSSMSLMTQFEQEVSNLQDIMHDI 134
LK +E ++L+ +I SE+L + + E S + +E+ +D +
Sbjct: 749 LKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATT 808
Query: 135 QNNEEVLTQRMQSLNEKFQNITDFWKRSLEE-MNINTDI---------FKSEAKHIHSQV 184
Q+N + Q Q+ + +K LEE +N +I F S + +++
Sbjct: 809 QSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTEL 868
Query: 185 TVQINSAEQEIKLLTERLKDLE---------DSTLRNIRTVKRQEEEDLLRVEEQLGSDT 235
+ + +++ + + ERL ++E DSTL+ + K E L + E++ + T
Sbjct: 869 SYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLT 928
Query: 236 KAIEKLEEEQHAL-FARDE------DLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQ 288
+ + L++ Q +L RD+ D N D + ++ L + I+++
Sbjct: 929 QEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKIS 988
Query: 289 DLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQ----KTLEGIQYDNSILKMQNELDIL 344
+ + ME+ T + + + + + +++ +TL DN I++ Q ++ L
Sbjct: 989 EEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSL 1048
Query: 345 KEKVHDF--IAYSSTGEKGTLK-------EYNIENK 371
++ ++ + S EK LK E IEN+
Sbjct: 1049 IQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQ 1084
Score = 45.8 bits (107), Expect = 6e-05
Identities = 59/294 (20%), Positives = 126/294 (42%), Gaps = 53/294 (18%)
Query: 79 LKLETNEFQQLQSKISLISE-KLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNN 137
LKL N ++ + SE + S ++ Q+ S+ MTQF +E N + + ++N
Sbjct: 2229 LKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNG 2288
Query: 138 EEVLTQRMQSLNEKFQN------------------ITDFWKRSLEEM-NINTDIFKSEAK 178
+ R+ +N F N I+ W++ L+ + N +FK+
Sbjct: 2289 IQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQT 2348
Query: 179 HIHSQVT-VQINSAEQEIK----------LLTERLKDLEDSTLRNIRTVKRQEEEDLLRV 227
S + Q+N Q+ K L TE++++LE+S L + +E ++++
Sbjct: 2349 LKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENS-LHEAKESAMHKESKIIKM 2407
Query: 228 EEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVS 287
+++L I KL+ + H +NK +E+ K + ++ +V+
Sbjct: 2408 QKELEVTNDIIAKLQAKVHE--------SNKC------LEKTKETIQVLQD------KVA 2447
Query: 288 QDLIETEKKMEDLTMQMFNMEDDMLKAVSEI-MEMQKTLEGIQYDNSILKMQNE 340
++++EDL M++ ++ + +K E E+ T ++Y ++++ E
Sbjct: 2448 LGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRE 2501
Score = 42.7 bits (99), Expect = 5e-04
Identities = 59/292 (20%), Positives = 129/292 (44%), Gaps = 31/292 (10%)
Query: 80 KLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEE 139
K + +EF+ L+ K K + ++ E ++ +L+ EV N QD+ +++ + E
Sbjct: 531 KNDLDEFEALERKT-----KKDQEMQLIHEISNLKNLVKH--AEVYN-QDLENELSSKVE 582
Query: 140 VLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQV-----TVQINSAEQE 194
+L ++ + +K Q D K +M+++ + E Q TV +++ +
Sbjct: 583 LLREKEDQI-KKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRES 641
Query: 195 IKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDED 254
L +E L+ E ++ + T +Q E D+ + QL + K LE+E + F
Sbjct: 642 AFLRSENLELKEK--MKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITK 699
Query: 255 LTNKLSDYEPKVEECKTHLPTIESAIHSVLR-VSQDLIETEKKMEDLTMQMFNMEDDMLK 313
LT+ + PK C L E I + + +++++ E E E++ + ++
Sbjct: 700 LTSLIDGKVPKDLLCNLEL---EGKITDLQKELNKEVEENEALREEVILL-----SELKS 751
Query: 314 AVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEKGTLKE 365
SE+ ++K ++ + I+ + K+K+ + + + +G L+E
Sbjct: 752 LPSEVERLRKEIQDKSEELHIITSE------KDKLFSEVVHKESRVQGLLEE 797
Score = 33.9 bits (76), Expect = 0.25
Identities = 52/261 (19%), Positives = 111/261 (42%), Gaps = 55/261 (21%)
Query: 67 EKFAKVENQYQLLKL------------ETNEFQQLQSKIS-LISEKLESTESILQEATSS 113
EK K+ YQ LK + N+ + S+ + L +EK+ E+ L EA S
Sbjct: 2337 EKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKES 2396
Query: 114 MS------LMTQFEQEVSN-----LQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRS 162
+ Q E EV+N LQ +H+ E + +Q L +K +K
Sbjct: 2397 AMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEE 2456
Query: 163 LEEMN---INTDIFKSE-AKHIHSQVTVQINSAEQE---IKLLTERLK---DLEDSTLRN 212
+E++ + D+ K + AK +++ + E + I+LL E L+ +D+++ +
Sbjct: 2457 IEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVIS 2516
Query: 213 IRTVKRQEEEDL---------------------LRVEEQLGSDTKAIEKLEEEQHALFAR 251
T + + L +R+E+++ + E+L ++++ L +
Sbjct: 2517 EHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSN 2576
Query: 252 DEDLTNKLSDYEPKVEECKTH 272
++ L+N++ ++ + + + H
Sbjct: 2577 NQHLSNEVKTWKERTLKREAH 2597
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 59.7 bits (143), Expect = 4e-09
Identities = 49/280 (17%), Positives = 135/280 (48%), Gaps = 21/280 (7%)
Query: 64 QQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQE 123
Q E+ A ++ L+ N+ +Q+ +I +K+++ E++LQ++ ++SL+ + ++
Sbjct: 489 QHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKERED 548
Query: 124 V-SNLQD------IMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSE 176
+ + +Q +++ +Q L +++ L EK +N ++ K++ E ++ K+
Sbjct: 549 LYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAH 608
Query: 177 AKHIHSQV----------TVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLR 226
+ +V Q+N +++++ L ++K + L + K + DL
Sbjct: 609 LRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIK-AKTELLLSAEAAKTAQRADL-- 665
Query: 227 VEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRV 286
+ L + A++ ++E + + + + +T KL D + + ++HL + S+ +
Sbjct: 666 -QNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQK 724
Query: 287 SQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLE 326
+++L KK+E ++++ ++ L+ + + ++ LE
Sbjct: 725 TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLE 764
Score = 49.3 bits (116), Expect = 6e-06
Identities = 60/308 (19%), Positives = 123/308 (39%), Gaps = 34/308 (11%)
Query: 64 QQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQE 123
Q E +++ L+ E + L +++S + +KL L+ + S +FE+E
Sbjct: 826 QHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKS------EFEKE 879
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQ 183
+ + D++ + L ++Q E K+SLE+ + K E + Q
Sbjct: 880 NQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQ 939
Query: 184 VTVQINSAEQ---EIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK 240
+ N+ +Q E + L + +L+ S+ + + ++ + E + V ++ + K ++
Sbjct: 940 LIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQ 999
Query: 241 LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKM--- 297
L + L A E ++ ++YE E K +L QDL E+K+
Sbjct: 1000 LTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLA 1059
Query: 298 ------------------EDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQN 339
++L +E D K ++ E K L+ IQ + S+
Sbjct: 1060 QEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSL----K 1115
Query: 340 ELDILKEK 347
E +++ EK
Sbjct: 1116 EKELVNEK 1123
Score = 47.4 bits (111), Expect = 2e-05
Identities = 59/272 (21%), Positives = 109/272 (40%), Gaps = 35/272 (12%)
Query: 78 LLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNN 137
+LK E + Q L ++L E+ +E + E S E +S L+ +
Sbjct: 225 VLKKELVQVQTLMDNMTL--ERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQE 282
Query: 138 EEVLTQRMQSLNEKFQNITDFWKRSLEEM-NINTDIFKSEAKHIHSQVTVQINSAEQEIK 196
V Q +Q L +T + E + D K E KH V+ + A
Sbjct: 283 VAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQA----- 337
Query: 197 LLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLT 256
T KDL+ L++ + E L R+ +L +A +KL+EE + + + L
Sbjct: 338 --TLHQKDLDCQQLQSRLSAS---ETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLK 392
Query: 257 NKLSDYEPKVEECKTHLPTIESAI---HSVL-------------------RVSQDLIETE 294
+ + + EE + H ++S I HS L S+ L++ E
Sbjct: 393 AEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKE 452
Query: 295 KKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLE 326
+++ DL +++ +E+ + + V+ E+Q L+
Sbjct: 453 QQVADLQLKLSRLEEQLKEKVTNSTELQHQLD 484
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/329 (17%), Positives = 132/329 (40%), Gaps = 50/329 (15%)
Query: 79 LKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNN- 137
L++E + + SE LES + L + ++ Q + +S I H+ NN
Sbjct: 774 LEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNR 833
Query: 138 --------------EEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKS-------E 176
+E L + ++ +K ++D K S E K+
Sbjct: 834 IQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKT 893
Query: 177 AKHIHSQVTVQINSAEQEIKLLTE--------------RLKDLEDSTLRNIRTVKRQEEE 222
K + Q+ VQ+ + +E K L + L +++ ++ T+K+ E+E
Sbjct: 894 CKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKE 953
Query: 223 D------LLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTI 276
+ + +++ K IE L+ E + +L NKL + ++ + L
Sbjct: 954 EQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKL---QQQLTQAAQELAAE 1010
Query: 277 ESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILK 336
+ I SVL+ + + ++++ + L + E ++L ++ +++ L Q D ++
Sbjct: 1011 KEKI-SVLQNNYE--KSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQED--LIS 1065
Query: 337 MQNELDILKEKVHDFIAYSSTGEKGTLKE 365
+N++ + + + +T E+ + K+
Sbjct: 1066 NRNQIGNQNKLIQELKTAKATLEQDSAKK 1094
Score = 41.2 bits (95), Expect = 0.002
Identities = 46/209 (22%), Positives = 92/209 (44%), Gaps = 24/209 (11%)
Query: 64 QQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQE 123
Q+ E K ++ ++ E Q L+ ++ E+L+ E I +EA + E
Sbjct: 1171 QKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKK-EFIEKEA--------KLHSE 1221
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFW---KRSLEEMNINTDIFKSEAKHI 180
+ + M + NE LT ++ +LNE + W +R + E+ TD + E +
Sbjct: 1222 IKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVL 1281
Query: 181 HSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK 240
+ TVQ N+ ++ LL LK + + ++T +L ++ +L + T A+++
Sbjct: 1282 --EATVQ-NNQDERRALLERCLKG--EGEIEKLQT-------KVLELQRKLDNTTAAVQE 1329
Query: 241 LEEEQHALFARDEDLTNKLSDYEPKVEEC 269
L E +L + N+ + +V+ C
Sbjct: 1330 LGRENQSLQIKHTQALNRKWAEDNEVQNC 1358
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 58.5 bits (140), Expect = 9e-09
Identities = 49/279 (17%), Positives = 126/279 (45%), Gaps = 33/279 (11%)
Query: 80 KLETNEFQ---QLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN-LQDIMHDIQ 135
K ET+ Q +L+ ++++L+ E ++ + + + + +Q + N ++D+M D++
Sbjct: 1377 KYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1436
Query: 136 NNEEVLTQRMQSLNEKFQNITDFWKRSLEEM------------NINTDIFKSEAKHIHSQ 183
+ + F + WK+ EE +++T++FK K+++ +
Sbjct: 1437 RSNAACAA-LDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFK--VKNVYEE 1493
Query: 184 VTVQINSAEQEIKLLTERLKDLEDST------LRNIRTVKRQEEEDLLRVEEQLGSDTKA 237
Q+ + +E K L + + DL + + + +K+Q E++ ++ L +
Sbjct: 1494 SLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEAS 1553
Query: 238 IE----KLEEEQHALFARDEDLTNKLSDYEPKVEECKTH----LPTIESAIHSVLRVSQD 289
+E K+ Q L ++ K+++ + ++++ K + + T++S + + +R D
Sbjct: 1554 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRND 1613
Query: 290 LIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGI 328
+ +KKME +M + + +E + + +GI
Sbjct: 1614 ALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGI 1652
Score = 47.8 bits (112), Expect = 2e-05
Identities = 60/311 (19%), Positives = 138/311 (44%), Gaps = 47/311 (15%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN 126
E+F K +++ L K E + + ++L+ EK + + EA S + EQ + N
Sbjct: 857 EEFQKTKDE--LAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKN 914
Query: 127 -------LQDIMHDIQNNEEV---LTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSE 176
++++ + EE+ LT + + L ++ + K+ ++++ +
Sbjct: 915 KIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSEL----KKDIDDLELTL------ 964
Query: 177 AKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEE------EDLLRVEEQ 230
++V + ++ E ++K LTE + L+++ + + K +E +DL E++
Sbjct: 965 -----AKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDK 1019
Query: 231 LGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQD- 289
+ TKA KLE++ +DL L + ++ + L + + L+++Q+
Sbjct: 1020 VNILTKAKTKLEQQV-------DDLEGSLE----QEKKLRMDLERAKRKLEGDLKLAQES 1068
Query: 290 LIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVH 349
++ E + L ++ E ++ +S+I + Q IQ I ++Q ++ L E++
Sbjct: 1069 TMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAV--EIQLQKKIKELQARIEELGEEIE 1126
Query: 350 DFIAYSSTGEK 360
A + EK
Sbjct: 1127 AERASRAKAEK 1137
Score = 46.2 bits (108), Expect = 5e-05
Identities = 58/250 (23%), Positives = 100/250 (40%), Gaps = 43/250 (17%)
Query: 60 WFVFQQSEKFAKVENQ--------YQLL------------KLETNEFQQLQSKISLISEK 99
W +Q+E+ K+ Q QLL KLE N+ QLQS++ + ++
Sbjct: 1692 WATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE-NDVSQLQSEVEEVIQE 1750
Query: 100 LESTESILQEATSSMSLMTQF---EQEVS--------NLQDIMHDIQNNEEVLTQRMQSL 148
+ E ++A + ++M + EQ+ S NL+ + D+Q+ + Q
Sbjct: 1751 SRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKG 1810
Query: 149 NEKFQNITDFWKRSLE-----EMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLK 203
+K + R LE E N + K KH + + E +L RL+
Sbjct: 1811 GKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVL--RLQ 1868
Query: 204 DLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYE 263
DL D +++ KRQ EE EEQ ++ KL+ E R + ++++
Sbjct: 1869 DLVDKLQAKVKSYKRQAEE----AEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLR 1924
Query: 264 PKVEECKTHL 273
K E T +
Sbjct: 1925 VKSREVHTKI 1934
Score = 40.4 bits (93), Expect = 0.003
Identities = 69/337 (20%), Positives = 134/337 (39%), Gaps = 40/337 (11%)
Query: 66 SEKFAKVENQYQ--LLKLET--NEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFE 121
S + KV+N Y+ L +LET E + LQ +IS ++E++ + E + Q E
Sbjct: 1481 STELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK---IKKQVE 1537
Query: 122 QEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI- 180
QE +Q + + + + E ++ + + + R + E + D K +
Sbjct: 1538 QEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVV 1597
Query: 181 ---HSQVTVQINSAEQEIKLLTERLKDLED-------------STLRNIRTVKRQEEEDL 224
S + +I S +++ + DL + +LRN R + +E
Sbjct: 1598 ETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQ 1657
Query: 225 LRVEEQLGSDTKAIEKL---EEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIH 281
L +++ L E+L E + L A E+L L E + + L +
Sbjct: 1658 LHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQ 1717
Query: 282 SVLRVSQDLIETEKKM-----------EDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQY 330
+ + LI T+KK+ E++ + N E+ KA+++ M + L+ Q
Sbjct: 1718 LLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQD 1777
Query: 331 DNSIL-KMQNELD-ILKEKVHDFIAYSSTGEKGTLKE 365
++ L +M+ L+ +K+ H KG K+
Sbjct: 1778 TSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ 1814
Score = 38.1 bits (87), Expect = 0.013
Identities = 51/286 (17%), Positives = 122/286 (42%), Gaps = 30/286 (10%)
Query: 63 FQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQ 122
F+ S +K+E++ + + ++LQ++I + E++E+ + +A S +++ +
Sbjct: 1088 FEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELE 1147
Query: 123 EVSNLQDIMHDIQNNEEV--LTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
E+S + EE T LN+K + +R LEE + + + +
Sbjct: 1148 EIS---------ERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKK 1198
Query: 181 HSQVTVQINSAEQEIKLLTERLK------DLEDSTLRNIRTVKRQEEEDLLRVEEQLGSD 234
H+ ++ ++ + ++L+ +E L + + + +L ++ L
Sbjct: 1199 HADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQ 1258
Query: 235 TKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETE 294
++ EEEQ L DLT + + + + E L ++ + + R Q +
Sbjct: 1259 VSELKTKEEEQQRLI---NDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQ---AST 1312
Query: 295 KKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNE 340
+++E+L Q+ ++ KA + + L+ ++D +L+ Q E
Sbjct: 1313 QQIEELKHQL----EEETKAKNALAH---ALQSSRHDCDLLREQYE 1351
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/309 (22%), Positives = 133/309 (43%), Gaps = 36/309 (11%)
Query: 66 SEKFAKVENQYQLLKLETNEFQQLQSKISLISEK-LESTESILQE----ATSSMSLMTQF 120
S++++ + Y+L + F + Q K + L S+++I QE T +L+T
Sbjct: 1340 SQQYSTIVKDYELQLMTYKAFVESQQKSPGKRRRMLSSSDAITQEFMDLRTRYTALVTLT 1399
Query: 121 EQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
Q V + D + ++ E+V+ + Q EK + + W +L NT + +A
Sbjct: 1400 TQHVKYISDALRRLEEEEKVVEEEKQEHVEKVKELLG-WVSTLAR---NT---QGKATSS 1452
Query: 181 HSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVK--------RQEEEDLLRVEEQLG 232
++ + I A E ++L+E L ++ I+T + + E++ ++ EQL
Sbjct: 1453 ETKESTDIEKAILEQQVLSEELTTKKEQVSEAIKTSQIFLAKHGHKLSEKEKKQISEQLN 1512
Query: 233 SDTKAIE--------KLEEEQHALFARDEDLT--NKLSDYEPKVEECKTHLPTIESAI-- 280
+ KA +L++ Q L + E T + + ++E+ + + E A+
Sbjct: 1513 ALNKAYHDLCDGSANQLQQLQSQLAHQTEQKTLQKQQNTCHQQLEDLCSWVGQAERALAG 1572
Query: 281 HSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNE 340
H QDL +K DL +++DD+ + + K +EG +N E
Sbjct: 1573 HQGRTTQQDLSALQKNQSDLK----DLQDDIQNRATSFATVVKDIEGFMEENQTKLSPRE 1628
Query: 341 LDILKEKVH 349
L L+EK+H
Sbjct: 1629 LTALREKLH 1637
Score = 39.7 bits (91), Expect = 0.004
Identities = 67/325 (20%), Positives = 128/325 (39%), Gaps = 28/325 (8%)
Query: 68 KFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLM---------- 117
K A+V +++ L L+ E + K+ +E E LQ+ + S M
Sbjct: 2127 KLAEVSQRFEQLCLQQQEKESSLKKLLPQAEMFEHLSGKLQQFMENKSRMLASGNQPDQD 2186
Query: 118 -TQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFK-- 174
T F Q++ L M D Q N + L + L+ D + N+ D +
Sbjct: 2187 ITHFFQQIQELNLEMEDQQENLDTLEHLVTELS-SCGFALDLCQHQDRVQNLRKDFTELQ 2245
Query: 175 ---SEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQL 231
E + S Q++ + ++ + LK+ E S ++ +E E + + L
Sbjct: 2246 KTVKEREKDASSCQEQLDEFRKLVRTFQKWLKETEGSIPPTETSMSAKELEKQIEHLKSL 2305
Query: 232 GSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTH--LPTIESAIHSV--LRVS 287
D + L EE + + L N + + + KT LP++ S++ SV
Sbjct: 2306 LDDWASKGTLVEE---INCKGTSLENLIMEITAPDSQGKTGSILPSVGSSVGSVNGYHTC 2362
Query: 288 QDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYD-NSILKMQNELDILKE 346
+DL E + M D+ ++ + + + + + +E + + NS+L+ L+ +E
Sbjct: 2363 KDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQW---LESKEE 2419
Query: 347 KVHDFIAYSSTGEKGTLKEYNIENK 371
+ A SS + T+K NK
Sbjct: 2420 VLKSMDAMSSPTKTETVKAQAESNK 2444
Score = 35.8 bits (81), Expect = 0.065
Identities = 61/297 (20%), Positives = 122/297 (41%), Gaps = 46/297 (15%)
Query: 67 EKFAKVENQYQLLK-------LETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQ 119
EK+ K EN Y +K L +E ++I+ +K+E L+ +S + +
Sbjct: 3902 EKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRMPPL 3961
Query: 120 FEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEM-----NINTDIFK 174
EV +++ + D + T ++ L F+ + KR EE+ + D+
Sbjct: 3962 IPAEVDKIRECISD----NKSATVELEKLQPSFEAL----KRRGEELIGRSQGADKDLAA 4013
Query: 175 SEAKHIHSQVT-----VQINSAEQEIKLL--TERLKDLEDSTLRNIRTVKRQEEEDLLRV 227
E + Q+ ++ + E+EIK L E + + T+K + +D++
Sbjct: 4014 KEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALLTTIK--DTQDIVHD 4071
Query: 228 EEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYE----PKVEEC-KTHLPTIESAIHS 282
E G D I++ E + + L +L + C +T P + +I
Sbjct: 4072 LESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDE 4131
Query: 283 VLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGI--QYDNSILKM 337
+ ++L +T K+ ++ +ED M AV + Q TL+ + DN+++K+
Sbjct: 4132 MNNAWENLNKTWKE------RLEKLEDAMQAAV----QYQDTLQAMFDWLDNTVIKL 4178
Score = 34.7 bits (78), Expect = 0.14
Identities = 59/276 (21%), Positives = 113/276 (40%), Gaps = 45/276 (16%)
Query: 101 ESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWK 160
E+T+SIL SL + S LQ + Q+ +E L +QS+ E QN+
Sbjct: 2017 ETTDSILSHF---QSLSYSLAERSSLLQKAIAQSQSVQESLESLLQSIGEVEQNLEGKQV 2073
Query: 161 RSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLR-----NIRT 215
SL I + + + + Q +S E +++T R + DST +
Sbjct: 2074 SSLSSGVIQEAL--ATNMKLKQDIARQKSSLEATREMVT-RFMETADSTTAAVLQGKLAE 2130
Query: 216 VKRQEEEDLLRVEEQLGSDTKAIEKLE-------------EEQHALFAR----DEDLTN- 257
V ++ E+ L+ +E+ S K + + E E + + A D+D+T+
Sbjct: 2131 VSQRFEQLCLQQQEKESSLKKLLPQAEMFEHLSGKLQQFMENKSRMLASGNQPDQDITHF 2190
Query: 258 --KLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAV 315
++ + ++E+ + +L T+E + TE + + +D +
Sbjct: 2191 FQQIQELNLEMEDQQENLDTLEHLV------------TELSSCGFALDLCQHQDRVQNLR 2238
Query: 316 SEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDF 351
+ E+QKT++ + D S Q +LD ++ V F
Sbjct: 2239 KDFTELQKTVKEREKDAS--SCQEQLDEFRKLVRTF 2272
Score = 32.0 bits (71), Expect = 0.94
Identities = 40/218 (18%), Positives = 94/218 (43%), Gaps = 18/218 (8%)
Query: 94 SLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQ 153
++++ + + + +L+E + Q + + D+ + + + +QS+N+K+
Sbjct: 2544 NMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGILTGPGDVSLSTSQVQKELQSINQKWV 2603
Query: 154 NITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNI 213
+TD K + I+ I KS +Q + ++++ + +RL ++ +
Sbjct: 2604 ELTD--KLNSRSSQIDQAIVKS------TQYQELLQDLSEKVRAVGQRL-SVQSAISTQP 2654
Query: 214 RTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHL 273
VK+Q EE ++ SD +E+L+ E ++L+ + + K +E K L
Sbjct: 2655 EAVKQQLEE-----TSEIRSD---LEQLDHEVKEAQTLCDELSVLIGEQYLK-DELKKRL 2705
Query: 274 PTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDM 311
T+ + + ++ D I + T Q M D++
Sbjct: 2706 ETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDEL 2743
Score = 32.0 bits (71), Expect = 0.94
Identities = 43/232 (18%), Positives = 95/232 (40%), Gaps = 30/232 (12%)
Query: 87 QQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQ 146
Q++ S ++ KLE S + + E+ + I D
Sbjct: 3043 QRVNSGCVMMENKLEGIGQFHCRVREMFSQLADLDDELDGMGAIGRDTD----------- 3091
Query: 147 SLNEKFQNITDFWKRSLEEMNINTDIFKSEAKH-IHSQVTVQINSAEQEIKLLTERLKDL 205
SL + +++ F + + + ++ + ++E +H + + T+ + ++E++ L ++ L
Sbjct: 3092 SLQSQIEDVRLFLNK-IHVLKLDIEASEAECRHMLEEEGTLDLLGLKRELEALNKQCGKL 3150
Query: 206 EDSTLRNIRTVKRQEE--------EDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTN 257
+ R RQE+ ED R + L T A E+ E Q + E +
Sbjct: 3151 TE------RGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEAEALQWVVGTEVEIINQ 3204
Query: 258 KLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMED 309
+L+D++ +E + ++ + V + Q LI++ K D+ +ME+
Sbjct: 3205 QLADFKMFQKE---QVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEHDMEE 3253
Score = 31.2 bits (69), Expect = 1.6
Identities = 55/263 (20%), Positives = 99/263 (37%), Gaps = 68/263 (25%)
Query: 74 NQYQLLKLETNEFQQL--------------QSKISLISEKLESTESILQEATSSMSLMTQ 119
N+ Q T +FQQ+ Q+K IS KLE +S LQE + Q
Sbjct: 2724 NRLQAALASTQQFQQMFDELRTWLDDKQSQQAKNCPISAKLERLQSQLQENEEFQKSLNQ 2783
Query: 120 FE--------------------QEVSNLQDIMHDIQNNEEVLTQR-----------MQSL 148
+E LQ+ + +++N+ E L+++ MQ
Sbjct: 2784 HSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVELKNHWEELSKKTADRQSRLKDCMQKA 2843
Query: 149 NEKFQNITDF--W----KRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERL 202
+ ++ D W K + E+ + D + E+ + S+ +N E+ LL E L
Sbjct: 2844 QKYQWHVEDLVPWIEDCKAKMSELRVTLDPVQLESSLLRSK--AMLNEVEKRRSLL-EIL 2900
Query: 203 KDLEDSTLRN-------IRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDL 255
D + + IR K +++ V E+L + T ++E++ + R +
Sbjct: 2901 NSAADILINSSEADEDGIRDEKAGINQNMDAVTEELQAKTGSLEEMTQ-------RLREF 2953
Query: 256 TNKLSDYEPKVEECKTHLPTIES 278
+ E KVE K L ++
Sbjct: 2954 QESFKNIEKKVEGAKHQLEIFDA 2976
Score = 30.0 bits (66), Expect = 3.6
Identities = 60/271 (22%), Positives = 114/271 (42%), Gaps = 61/271 (22%)
Query: 89 LQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSL 148
L+ K ++S K+E +S L+EA ++L T+F+ ++LQ+ ++ LT QSL
Sbjct: 4461 LEQKWHVVSSKMEERKSKLEEA---LNLATEFQ---NSLQEFIN-------WLTLAEQSL 4507
Query: 149 NEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDS 208
N S + +NT + + E H ++N+ +I L D
Sbjct: 4508 N----------IASPPSLILNTVLSQIEE---HKVFANEVNAHRDQIIEL--------DQ 4546
Query: 209 TLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEE 268
T ++ + +++D++ ++ L S EK+ + R + L D + ++
Sbjct: 4547 TGNQLKFL--SQKQDVVLIKNLLVSVQSRWEKVVQ-------RSIERGRSLDDARKRAKQ 4597
Query: 269 CKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGI 328
H + D +E + D +++ N D + +S+ E QKTL G
Sbjct: 4598 -----------FHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGK 4646
Query: 329 Q--YDNSI-----LKMQNELDILKEKVHDFI 352
Q YD +I LK + L +K+ +F+
Sbjct: 4647 QPVYDTTIRTGRALKEKTLLPEDSQKLDNFL 4677
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 57.4 bits (137), Expect = 2e-08
Identities = 51/283 (18%), Positives = 125/283 (44%), Gaps = 29/283 (10%)
Query: 80 KLETNEFQ---QLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN-LQDIMHDIQ 135
K ET+ Q +L+ ++++L++ E ++ + + + + +Q + N ++D+M D++
Sbjct: 1380 KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439
Query: 136 NNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEA----------KHIHSQVT 185
+ F I WK+ EE + + + EA K+ + +
Sbjct: 1440 RTNAACAA-LDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESL 1498
Query: 186 VQINSAEQEIKLLTERLKDLEDST------LRNIRTVKRQEEEDLLRVEEQLGSDTKAIE 239
Q+ + ++E K L + + DL + + + +K+Q E++ ++ L ++E
Sbjct: 1499 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLE 1558
Query: 240 ----KLEEEQHALFARDEDLTNKLSDYEPKVEECKTH----LPTIESAIHSVLRVSQDLI 291
K+ Q L ++ K+++ + ++++ K + + +++S + + +R D I
Sbjct: 1559 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAI 1618
Query: 292 ETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSI 334
+KKME +M + + +E + + +GI D I
Sbjct: 1619 RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQI 1661
Score = 46.6 bits (109), Expect = 4e-05
Identities = 40/180 (22%), Positives = 83/180 (46%), Gaps = 7/180 (3%)
Query: 192 EQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFAR 251
E +IK +TER +D E+ + KR+ E++ +++ + + K+E+E+HA +
Sbjct: 922 EAKIKEVTERAED-EEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980
Query: 252 DEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDM 311
++LT +++ + + + ++ A L DL E K+ LT +E
Sbjct: 981 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL---DDLQAEEDKVNTLTKAKIKLE-QQ 1036
Query: 312 LKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDF-IAYSSTGEKGTLKEYNIEN 370
+ + +E +K L + + + K++ +L + +E + D EK KE+ I N
Sbjct: 1037 VDDLEGSLEQEKKLR-MDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISN 1095
Score = 43.5 bits (101), Expect = 3e-04
Identities = 60/291 (20%), Positives = 118/291 (40%), Gaps = 38/291 (13%)
Query: 71 KVENQYQ--LLKLET--NEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN 126
K++N Y+ L +LET E + LQ +IS ++E++ + E + Q EQE
Sbjct: 1489 KIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK---IKKQVEQEKCE 1545
Query: 127 LQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSE----AKHIHS 182
LQ + + + + E ++ + + + R + E + D K + + S
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605
Query: 183 QVTVQINSAEQEIKLLTERLKDLED-------------STLRNIRTVK------RQEEED 223
+ +I S I+L + DL + LRN R + + +D
Sbjct: 1606 TLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDD 1665
Query: 224 LLRVEEQLGSDTKAIEK----LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIE-- 277
LR +E L +E+ L+ E L A E E ++ + + +
Sbjct: 1666 ALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ 1725
Query: 278 --SAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLE 326
S I++ ++ D+ + + +MED+ + N E+ KA+++ M + L+
Sbjct: 1726 NTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELK 1776
Score = 42.0 bits (97), Expect = 0.001
Identities = 48/261 (18%), Positives = 113/261 (43%), Gaps = 24/261 (9%)
Query: 71 KVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMS--------LMTQFEQ 122
K+E Q L+ + ++L+ + KLE + QE+ + + + E
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
Query: 123 EVSNLQDIMHD-------IQNNEEVLTQRMQSLNEKFQ-NITDFWKRSLEEMNINTDI-- 172
E+SNLQ + D +Q + L R++ L E+ + K + +++ ++
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1151
Query: 173 FKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRN---IRTVKRQEEEDLLRVEE 229
+ + QI ++ + +DLE++TL++ T++++ + + + E
Sbjct: 1152 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGE 1211
Query: 230 QLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQD 289
Q+ + + +KLE+E+ + +DL + + + T+E + S L+ ++
Sbjct: 1212 QIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQL-SELKSKEE 1270
Query: 290 LIETEKKMEDLTMQMFNMEDD 310
E ++ + DLT Q ++ +
Sbjct: 1271 --EQQRLINDLTAQRGRLQTE 1289
Score = 40.4 bits (93), Expect = 0.003
Identities = 56/290 (19%), Positives = 125/290 (43%), Gaps = 38/290 (13%)
Query: 63 FQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQ 122
F+ S +K+E++ L + ++LQ++I + E++E+ + +A S +++ +
Sbjct: 1091 FEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Query: 123 EVSNLQDIMHDIQNNEEV--LTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
E+S + EE T +N+K + +R LEE + + + +
Sbjct: 1151 EIS---------ERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1201
Query: 181 HSQVTVQINSAEQEIKLLTERLKDLE-------DSTLRNIRTVKRQE---EEDLLRVEEQ 230
H+ ++ ++ + ++L+ + D N+ TV + + E+ +E+Q
Sbjct: 1202 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
Query: 231 LGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDL 290
L ++ EEEQ L DLT + + + E L E+ + + R Q
Sbjct: 1262 LSE----LKSKEEEQQRLI---NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAF 1314
Query: 291 IETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNE 340
+ ++E+L Q+ ++ +KA + + L+ ++D +L+ Q E
Sbjct: 1315 TQ---QIEELKRQL----EEEIKAKNALAH---ALQSSRHDCDLLREQYE 1354
Score = 39.7 bits (91), Expect = 0.004
Identities = 48/208 (23%), Positives = 85/208 (40%), Gaps = 23/208 (11%)
Query: 80 KLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQF---EQEVS--------NLQ 128
KLET + Q+Q ++ I ++ + E ++A + ++M + EQ+ S N++
Sbjct: 1735 KLET-DISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1793
Query: 129 DIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLE-----EMNINTDIFKSEAKHIHSQ 183
+ D+Q + Q +K + R LE E N + K KH
Sbjct: 1794 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRV 1853
Query: 184 VTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEE 243
+ + E +L RL+DL D +++ KRQ EE EEQ ++ KL+
Sbjct: 1854 KELTYQTEEDRKNIL--RLQDLVDKLQAKVKSYKRQAEE----AEEQSNTNLAKFRKLQH 1907
Query: 244 EQHALFARDEDLTNKLSDYEPKVEECKT 271
E R + ++++ K E T
Sbjct: 1908 ELEEAEERADIAESQVNKLRVKSREVHT 1935
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 57.4 bits (137), Expect = 2e-08
Identities = 51/283 (18%), Positives = 125/283 (44%), Gaps = 29/283 (10%)
Query: 80 KLETNEFQ---QLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN-LQDIMHDIQ 135
K ET+ Q +L+ ++++L++ E ++ + + + + +Q + N ++D+M D++
Sbjct: 1380 KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439
Query: 136 NNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEA----------KHIHSQVT 185
+ F I WK+ EE + + + EA K+ + +
Sbjct: 1440 RTNAACAA-LDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESL 1498
Query: 186 VQINSAEQEIKLLTERLKDLEDST------LRNIRTVKRQEEEDLLRVEEQLGSDTKAIE 239
Q+ + ++E K L + + DL + + + +K+Q E++ ++ L ++E
Sbjct: 1499 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLE 1558
Query: 240 ----KLEEEQHALFARDEDLTNKLSDYEPKVEECKTH----LPTIESAIHSVLRVSQDLI 291
K+ Q L ++ K+++ + ++++ K + + +++S + + +R D I
Sbjct: 1559 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAI 1618
Query: 292 ETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSI 334
+KKME +M + + +E + + +GI D I
Sbjct: 1619 RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQI 1661
Score = 46.6 bits (109), Expect = 4e-05
Identities = 40/180 (22%), Positives = 83/180 (46%), Gaps = 7/180 (3%)
Query: 192 EQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFAR 251
E +IK +TER +D E+ + KR+ E++ +++ + + K+E+E+HA +
Sbjct: 922 EAKIKEVTERAED-EEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980
Query: 252 DEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDM 311
++LT +++ + + + ++ A L DL E K+ LT +E
Sbjct: 981 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL---DDLQAEEDKVNTLTKAKIKLE-QQ 1036
Query: 312 LKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHDF-IAYSSTGEKGTLKEYNIEN 370
+ + +E +K L + + + K++ +L + +E + D EK KE+ I N
Sbjct: 1037 VDDLEGSLEQEKKLR-MDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISN 1095
Score = 43.5 bits (101), Expect = 3e-04
Identities = 60/291 (20%), Positives = 118/291 (40%), Gaps = 38/291 (13%)
Query: 71 KVENQYQ--LLKLET--NEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN 126
K++N Y+ L +LET E + LQ +IS ++E++ + E + Q EQE
Sbjct: 1489 KIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK---IKKQVEQEKCE 1545
Query: 127 LQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSE----AKHIHS 182
LQ + + + + E ++ + + + R + E + D K + + S
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605
Query: 183 QVTVQINSAEQEIKLLTERLKDLED-------------STLRNIRTVK------RQEEED 223
+ +I S I+L + DL + LRN R + + +D
Sbjct: 1606 TLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDD 1665
Query: 224 LLRVEEQLGSDTKAIEK----LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIE-- 277
LR +E L +E+ L+ E L A E E ++ + + +
Sbjct: 1666 ALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ 1725
Query: 278 --SAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLE 326
S I++ ++ D+ + + +MED+ + N E+ KA+++ M + L+
Sbjct: 1726 NTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELK 1776
Score = 42.0 bits (97), Expect = 0.001
Identities = 48/261 (18%), Positives = 113/261 (43%), Gaps = 24/261 (9%)
Query: 71 KVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMS--------LMTQFEQ 122
K+E Q L+ + ++L+ + KLE + QE+ + + + E
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
Query: 123 EVSNLQDIMHD-------IQNNEEVLTQRMQSLNEKFQ-NITDFWKRSLEEMNINTDI-- 172
E+SNLQ + D +Q + L R++ L E+ + K + +++ ++
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1151
Query: 173 FKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRN---IRTVKRQEEEDLLRVEE 229
+ + QI ++ + +DLE++TL++ T++++ + + + E
Sbjct: 1152 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGE 1211
Query: 230 QLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQD 289
Q+ + + +KLE+E+ + +DL + + + T+E + S L+ ++
Sbjct: 1212 QIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQL-SELKSKEE 1270
Query: 290 LIETEKKMEDLTMQMFNMEDD 310
E ++ + DLT Q ++ +
Sbjct: 1271 --EQQRLINDLTAQRGRLQTE 1289
Score = 40.4 bits (93), Expect = 0.003
Identities = 56/290 (19%), Positives = 125/290 (43%), Gaps = 38/290 (13%)
Query: 63 FQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQ 122
F+ S +K+E++ L + ++LQ++I + E++E+ + +A S +++ +
Sbjct: 1091 FEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Query: 123 EVSNLQDIMHDIQNNEEV--LTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
E+S + EE T +N+K + +R LEE + + + +
Sbjct: 1151 EIS---------ERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1201
Query: 181 HSQVTVQINSAEQEIKLLTERLKDLE-------DSTLRNIRTVKRQE---EEDLLRVEEQ 230
H+ ++ ++ + ++L+ + D N+ TV + + E+ +E+Q
Sbjct: 1202 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
Query: 231 LGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDL 290
L ++ EEEQ L DLT + + + E L E+ + + R Q
Sbjct: 1262 LSE----LKSKEEEQQRLI---NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAF 1314
Query: 291 IETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNE 340
+ ++E+L Q+ ++ +KA + + L+ ++D +L+ Q E
Sbjct: 1315 TQ---QIEELKRQL----EEEIKAKNALAH---ALQSSRHDCDLLREQYE 1354
Score = 39.7 bits (91), Expect = 0.004
Identities = 48/208 (23%), Positives = 85/208 (40%), Gaps = 23/208 (11%)
Query: 80 KLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQF---EQEVS--------NLQ 128
KLET + Q+Q ++ I ++ + E ++A + ++M + EQ+ S N++
Sbjct: 1735 KLET-DISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1793
Query: 129 DIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLE-----EMNINTDIFKSEAKHIHSQ 183
+ D+Q + Q +K + R LE E N + K KH
Sbjct: 1794 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRV 1853
Query: 184 VTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEE 243
+ + E +L RL+DL D +++ KRQ EE EEQ ++ KL+
Sbjct: 1854 KELTYQTEEDRKNIL--RLQDLVDKLQAKVKSYKRQAEE----AEEQSNTNLAKFRKLQH 1907
Query: 244 EQHALFARDEDLTNKLSDYEPKVEECKT 271
E R + ++++ K E T
Sbjct: 1908 ELEEAEERADIAESQVNKLRVKSREVHT 1935
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 57.4 bits (137), Expect = 2e-08
Identities = 48/263 (18%), Positives = 117/263 (44%), Gaps = 31/263 (11%)
Query: 80 KLETNEFQ---QLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSN-LQDIMHDIQ 135
K ET+ Q +L+ ++++L+ E ++ + S + + + + N ++D+M D++
Sbjct: 1376 KYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1435
Query: 136 NNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEI 195
+ + F I WK+ EE + + EA+ + +++
Sbjct: 1436 RSNAAAAA-LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELF---------- 1484
Query: 196 KLLTERLKDLEDSTLRNIRTVKRQE---EEDLLRVEEQLGSDTKAIEKLEEEQHALFARD 252
+LK+ + +L ++ T KR+ +E++ + EQLG K + +LE+ + L
Sbjct: 1485 -----KLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEK 1539
Query: 253 EDLTNKLSDYEPKVEECKTHLPTIESAIHSV-LRVSQDLIETEKKMEDLTMQMFNMEDDM 311
+L + L + E +E + + + + + + + L E +++ME + D +
Sbjct: 1540 LELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSL 1599
Query: 312 -------LKAVSEIMEMQKTLEG 327
++ +E++ ++K +EG
Sbjct: 1600 QTSLDAETRSRNEVLRVKKKMEG 1622
Score = 51.2 bits (121), Expect = 1e-06
Identities = 58/286 (20%), Positives = 118/286 (41%), Gaps = 38/286 (13%)
Query: 71 KVENQYQLLKLETNEFQQLQSKISLISEKLESTES-ILQEATSSMSLMTQFEQEVSNLQD 129
KV Q ++ KLE LQS + LE E IL+ + + E++++ +
Sbjct: 1530 KVRKQLEVEKLE------LQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDE 1583
Query: 130 IMHDIQNNEEVLTQRMQ-SLNEKFQNITDFW--KRSLEEMNINTDIFKSEAKHIHSQVTV 186
M + N + + +Q SL+ + ++ + K+ +E +I S A + ++
Sbjct: 1584 EMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQK 1643
Query: 187 QINSAEQEIK--------------------LLTERLKDLEDSTLRNIRTVKRQEEEDLLR 226
Q+ S + +K + ER +L + L +R V Q E
Sbjct: 1644 QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 1703
Query: 227 VEEQLGSDTKAIEKLEEEQHALFAR----DEDLTNKLSDYEPKVEECKTHLPTIESAIHS 282
E++L ++ ++ L + +L + + DLT S+ E V+EC+ + AI
Sbjct: 1704 AEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITD 1763
Query: 283 VLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGI 328
++++L KK +D + + M+ +M + + ++ E I
Sbjct: 1764 AAMMAEEL----KKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQI 1805
Score = 48.9 bits (115), Expect = 7e-06
Identities = 68/336 (20%), Positives = 142/336 (42%), Gaps = 65/336 (19%)
Query: 88 QLQSKISLISEKLESTESILQEATSSMSLM----TQFEQEVSNLQDIM-------HDIQN 136
QL++K+ ++E+LE E + E T+ + ++ ++++ +L+ + H +N
Sbjct: 916 QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 975
Query: 137 NEEVLTQRMQSLNEKFQNIT-------DFWKRSLEEMNINTDIFKSEAKH---IHSQVTV 186
+ LT+ M L+E +T + +++L+++ + D S +K + QV
Sbjct: 976 KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDD 1035
Query: 187 QINSAEQE-----------------IKLLTERLKDLEDSTLR------------NIRTVK 217
S EQE +KL E + DLE+ L+ N + K
Sbjct: 1036 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSK 1095
Query: 218 RQEEEDL-LRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTI 276
++E+ L L+++++L + IE+LEEE A + SD ++EE L
Sbjct: 1096 IEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEA 1155
Query: 277 ESAIHSVLRVSQ----DLIETEKKMEDLTMQ--------MFNMEDDMLKAVSEIMEMQKT 324
A + +++ + + + +E+ T+Q D + + +I +Q+
Sbjct: 1156 GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRV 1215
Query: 325 LEGIQYDNSILKMQNELDILKEKVHDFIAYSSTGEK 360
+ ++ + S K+ ELD + + I + EK
Sbjct: 1216 KQKLEKEKSEFKL--ELDDVTSNMEQIIKAKANLEK 1249
Score = 45.8 bits (107), Expect = 6e-05
Identities = 44/241 (18%), Positives = 113/241 (46%), Gaps = 18/241 (7%)
Query: 117 MTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSE 176
M ++E +++ + + + L ++M SL ++ ++ + E+ N+N +
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQ--LQVQAEQDNLN------D 902
Query: 177 AKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTK 236
A+ Q+ E ++K + ERL+D E+ + KR+ E++ +++ +
Sbjct: 903 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKKDIDDLEL 961
Query: 237 AIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSV---LRVSQDLIET 293
+ K+E+E+HA + ++LT +++ + + + ++ A L+V +D + +
Sbjct: 962 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNS 1021
Query: 294 -EKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYD-----NSILKMQNELDILKEK 347
K L Q+ ++E + + M++++ ++ D SI+ ++N+ L+EK
Sbjct: 1022 LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081
Query: 348 V 348
+
Sbjct: 1082 L 1082
Score = 38.1 bits (87), Expect = 0.013
Identities = 43/185 (23%), Positives = 82/185 (44%), Gaps = 25/185 (13%)
Query: 77 QLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQ- 135
Q K+E+ + QLQS++ ++ + E ++A + ++M + E+ QD ++
Sbjct: 1728 QKKKMES-DLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAE---ELKKEQDTSAHLER 1783
Query: 136 ---NNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSE--AKHIHSQVTVQ-IN 189
N E+ + L+E Q K+ L+++ + E A+ + +V+ +
Sbjct: 1784 MKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMR 1843
Query: 190 SAEQEIKLLTE----------RLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIE 239
+E+ IK LT RL+DL D ++ KRQ EE EEQ ++
Sbjct: 1844 KSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEE----AEEQANTNLSKFR 1899
Query: 240 KLEEE 244
K++ E
Sbjct: 1900 KVQHE 1904
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 57.4 bits (137), Expect = 2e-08
Identities = 64/294 (21%), Positives = 137/294 (46%), Gaps = 31/294 (10%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEA----TSSMSLMTQF 120
+ E+ K E+Q + L+ + E + ++ L EKL+ S L++ + S S TQ
Sbjct: 393 KDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQL 452
Query: 121 EQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
+ +++ D+ N EV+ R++ L + E+++ D+ K ++
Sbjct: 453 HLNLEKEKNLTKDLLNELEVVKSRVKELECSESRL------EKAELSLKDDLTKLKS--- 503
Query: 181 HSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK 240
TV + E K + E++K E+ + + + E+ ++ V E+L ++K + K
Sbjct: 504 ---FTVML---VDERKNMMEKIKQ-EERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 556
Query: 241 L----EEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIE-TEK 295
L EE+ + L ++L KL E K E + ++ + + V +++ +
Sbjct: 557 LKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSR 616
Query: 296 KMEDLTMQMFNMEDDMLKAVS-EIMEMQKTLEGIQ-YDNSILKMQNELDILKEK 347
K +LT ED+ +K ++ EI ++K L+ ++ + ++K ++E D L++K
Sbjct: 617 KGSELTCP----EDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQK 666
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/300 (18%), Positives = 134/300 (44%), Gaps = 19/300 (6%)
Query: 65 QSEKFAKVENQYQLLKLETN----EFQQLQSKISLISEKLEST-----ESILQEATSSMS 115
+ EK +V ++ +L E + +++ S++ + EK + T E +L
Sbjct: 119 EPEKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRR 178
Query: 116 LMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKS 175
+ + E E D M+ + +L Q + L + + + R +E + +
Sbjct: 179 TVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRD 238
Query: 176 EAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDT 235
E + S + ++ + I+ L + + ++D T + R+EEE L + + D
Sbjct: 239 ELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQK-----LREEEEKLKAITSKSKEDR 293
Query: 236 KAIEKLE---EEQHALFARD-EDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLI 291
+ + KLE E + + F+++ E++ KL++ E + + L + I + +++L
Sbjct: 294 QKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQ 353
Query: 292 ETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQK-TLEGIQYDNSILKMQNELDILKEKVHD 350
+ E+++++L ++ E ++E+ ++K LE D I K +++ L++K+ +
Sbjct: 354 KAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQE 413
Score = 39.3 bits (90), Expect = 0.006
Identities = 54/264 (20%), Positives = 105/264 (39%), Gaps = 33/264 (12%)
Query: 93 ISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKF 152
+ L+ E+ E I QE L F+ E + D+ + + L + + EK
Sbjct: 506 VMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKV 565
Query: 153 QNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRN 212
N+T R +E+ KSE + S+++ ++ LL +RL +E+
Sbjct: 566 YNLT----RERDEL---IGKLKSEEEK-SSELSCSVD-------LLKKRLDGIEEVEREI 610
Query: 213 IRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTH 272
R R+ E + ++ T IE+L++ L + DL +Y+ ++ +T
Sbjct: 611 TRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTE 670
Query: 273 -------LPTIESAIHSVLR---------VSQDL-IETEKKMEDLTMQMFNMEDDMLK-A 314
+E H + + VSQ+ + ++E+ + E LK
Sbjct: 671 QDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEK 730
Query: 315 VSEIMEMQKTLEGIQYDNSILKMQ 338
+ E+M + L +Q D S+L+ +
Sbjct: 731 IHELMNKEDQLSQLQVDYSVLQQR 754
Score = 31.6 bits (70), Expect = 1.2
Identities = 50/243 (20%), Positives = 103/243 (42%), Gaps = 24/243 (9%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMH 132
E+ QLL + E Q + I ++ K E T+ + EA + + + + +
Sbjct: 78 EDLIQLLSIMEGELQAREDVIHML--KTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQ 135
Query: 133 DIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAE 192
+ E+V + + L+ + + ++R LE++ + A+ H + ++ E
Sbjct: 136 EKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLL--------AEKCHRRTVYEL---E 184
Query: 193 QEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHA--LFA 250
E T+ + +D T + QE E L ++ EQ KA + +E+++A L
Sbjct: 185 NEKHKHTDYMNKSDDFT-----NLLEQERERLKKLLEQ----EKAYQARKEKENAKRLNK 235
Query: 251 RDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDD 310
++L S V+E + H+ + V ++Q L E E+K++ +T +
Sbjct: 236 LRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQK 295
Query: 311 MLK 313
+LK
Sbjct: 296 LLK 298
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 57.0 bits (136), Expect = 3e-08
Identities = 64/305 (20%), Positives = 130/305 (42%), Gaps = 45/305 (14%)
Query: 64 QQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSM--------- 114
Q++EK VEN+ LK + + +++ L +EKL + L+EA +
Sbjct: 504 QENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVR 563
Query: 115 --SLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDI 172
T+ + +S L+ + ++Q +L N K Q D+++ L+ +
Sbjct: 564 LRKSHTEMSKSISQLESLNRELQERNRILE------NSKSQTDKDYYQ--LQAILEAERR 615
Query: 173 FKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLG 232
+ + + +I S ++E+K L L+ +E + + + E++ +E L
Sbjct: 616 DRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGER-KEAQDMLNHSEKEKNNLEIDLN 674
Query: 233 SDTKAI-EKLEEEQHALFARDEDLTNK-----------LSDYEPKVEECKTHLPTIESAI 280
K++ ++LE+E + LT+K + + E K++E + E+ +
Sbjct: 675 YKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRV 734
Query: 281 HSVLR----VSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILK 336
+ + + DL ++++K+E LT MED++ TL+ Q N L
Sbjct: 735 VQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEV---------KNLTLQLEQESNKRLL 785
Query: 337 MQNEL 341
+QNEL
Sbjct: 786 LQNEL 790
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/144 (23%), Positives = 69/144 (47%), Gaps = 5/144 (3%)
Query: 66 SEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVS 125
+EK K E +Y+L K E + + ++ +E+ T+++ + A + +++ +
Sbjct: 963 TEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKA 1022
Query: 126 NLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVT 185
N QD+ + N ++ + Q EKF + ++ L +M E H +++
Sbjct: 1023 NTQDLRKKEKENRKLQLELNQE-REKFNQMVVKHQKELNDMQAQ---LVEECAH-RNELQ 1077
Query: 186 VQINSAEQEIKLLTERLKDLEDST 209
+Q+ S E +I+ L +L DL DST
Sbjct: 1078 MQLASKESDIEQLRAKLLDLSDST 1101
Score = 34.7 bits (78), Expect = 0.14
Identities = 67/322 (20%), Positives = 137/322 (42%), Gaps = 48/322 (14%)
Query: 75 QYQLLKLETNEFQQLQSKISLISEKLESTE--SILQEATSSMSLMTQFEQEVSNLQDIMH 132
+++L +L T +++ + ++ + ++LE+ + S L + T L + E++ +
Sbjct: 822 EFELAQL-TKQYRGNEGQMRELQDQLEAEQYFSTLYK-TQVKELKEEIEEKNRENLKKIQ 879
Query: 133 DIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNIN-TDIFKSEAKHIHSQVTVQ---I 188
++QN +E L ++ K ++ + LEE T K A ++T + +
Sbjct: 880 ELQNEKETLATQLDLAETKAES-EQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTV 938
Query: 189 NSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHAL 248
+ E+ +LT+ ++ L +K+ EEE L EE++ + A EK + L
Sbjct: 939 SRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTL 998
Query: 249 FARDEDLTNKLSDY----EPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQM 304
NKL++ + K++ K + +QDL + EK+ L +++
Sbjct: 999 ---KTQAVNKLAEIMNRKDFKIDRKKAN--------------TQDLRKKEKENRKLQLEL 1041
Query: 305 FNMEDD-----MLKAVSEIMEMQKTLEGIQYDNSILKMQ-----NELDILKEKVHDFIAY 354
N E + ++K E+ +MQ L + L+MQ ++++ L+ K+ D
Sbjct: 1042 -NQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLSDS 1100
Query: 355 SSTGE-------KGTLKEYNIE 369
+S G L E IE
Sbjct: 1101 TSVASFPSADETDGNLPESRIE 1122
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 [Homo
sapiens]
Length = 1288
Score = 57.0 bits (136), Expect = 3e-08
Identities = 62/282 (21%), Positives = 124/282 (43%), Gaps = 37/282 (13%)
Query: 89 LQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSL 148
LQ +I S + S + + SL+ + +E N + +QN+ + + MQ
Sbjct: 740 LQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME--SQLQNDSK---KAMQIQ 794
Query: 149 NEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDS 208
+K Q LEE + + E ++ + T I ++ + L ++K+LE +
Sbjct: 795 EQKVQ---------LEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEAN 845
Query: 209 TLRNIRTVKRQE--EEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTN--------K 258
L K+Q+ EE++ + + + + K+E E L ++ N K
Sbjct: 846 VLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDK 905
Query: 259 LSDYEPKVEEC-----------KTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNM 307
L +++EC KT ++ A SVLR +++ +TEK+++DLT ++ ++
Sbjct: 906 LDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSL 965
Query: 308 EDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVH 349
ED + V +++L IQ ++ + EL +++E H
Sbjct: 966 EDKAAEVVKNTNAAEESLPEIQKEHR--NLLQELKVIQENEH 1005
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/319 (17%), Positives = 146/319 (45%), Gaps = 29/319 (9%)
Query: 60 WFVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQ 119
+++++ ++ A++E Q + + +T E + K +++S ++++ +++ ++ +T+
Sbjct: 325 YYIYELQKRIAEMETQKEKIHEDTKEINE---KSNILSNEMKAKNKDVKDTEKKLNKITK 381
Query: 120 FEQEVSN--LQDIMHDIQNNEEV--LTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKS 175
F +E Q + D+Q E++ T + + L ++ Q K +EE +
Sbjct: 382 FIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKD----KEKVEEFKS----IPA 433
Query: 176 EAKHIHSQVTVQINSAEQEIKLLTERLKDLEDST---LRNIRTVKRQEEEDLLRVEEQLG 232
++ +I ++ T + N+ E+E + ++LK++ DS + ++ K E++L+ + +
Sbjct: 434 KSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVN 493
Query: 233 SDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVL----RVSQ 288
++ + E +R ++L+ + + L ++AI + + Q
Sbjct: 494 EARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQ 553
Query: 289 DLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKV 348
+L E EK+++ LT + N + + ++ E + +L + +L I++EK
Sbjct: 554 ELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDA-----IIQEKK 608
Query: 349 HDFI--AYSSTGEKGTLKE 365
I Y G+ G + E
Sbjct: 609 SGRIPGIYGRLGDLGAIDE 627
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 [Homo
sapiens]
Length = 1288
Score = 57.0 bits (136), Expect = 3e-08
Identities = 62/282 (21%), Positives = 124/282 (43%), Gaps = 37/282 (13%)
Query: 89 LQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSL 148
LQ +I S + S + + SL+ + +E N + +QN+ + + MQ
Sbjct: 740 LQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME--SQLQNDSK---KAMQIQ 794
Query: 149 NEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDS 208
+K Q LEE + + E ++ + T I ++ + L ++K+LE +
Sbjct: 795 EQKVQ---------LEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEAN 845
Query: 209 TLRNIRTVKRQE--EEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTN--------K 258
L K+Q+ EE++ + + + + K+E E L ++ N K
Sbjct: 846 VLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDK 905
Query: 259 LSDYEPKVEEC-----------KTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNM 307
L +++EC KT ++ A SVLR +++ +TEK+++DLT ++ ++
Sbjct: 906 LDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSL 965
Query: 308 EDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVH 349
ED + V +++L IQ ++ + EL +++E H
Sbjct: 966 EDKAAEVVKNTNAAEESLPEIQKEHR--NLLQELKVIQENEH 1005
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/319 (17%), Positives = 146/319 (45%), Gaps = 29/319 (9%)
Query: 60 WFVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQ 119
+++++ ++ A++E Q + + +T E + K +++S ++++ +++ ++ +T+
Sbjct: 325 YYIYELQKRIAEMETQKEKIHEDTKEINE---KSNILSNEMKAKNKDVKDTEKKLNKITK 381
Query: 120 FEQEVSN--LQDIMHDIQNNEEV--LTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKS 175
F +E Q + D+Q E++ T + + L ++ Q K +EE +
Sbjct: 382 FIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKD----KEKVEEFKS----IPA 433
Query: 176 EAKHIHSQVTVQINSAEQEIKLLTERLKDLEDST---LRNIRTVKRQEEEDLLRVEEQLG 232
++ +I ++ T + N+ E+E + ++LK++ DS + ++ K E++L+ + +
Sbjct: 434 KSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVN 493
Query: 233 SDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVL----RVSQ 288
++ + E +R ++L+ + + L ++AI + + Q
Sbjct: 494 EARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQ 553
Query: 289 DLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKV 348
+L E EK+++ LT + N + + ++ E + +L + +L I++EK
Sbjct: 554 ELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDA-----IIQEKK 608
Query: 349 HDFI--AYSSTGEKGTLKE 365
I Y G+ G + E
Sbjct: 609 SGRIPGIYGRLGDLGAIDE 627
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 57.0 bits (136), Expect = 3e-08
Identities = 64/299 (21%), Positives = 137/299 (45%), Gaps = 25/299 (8%)
Query: 64 QQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQE 123
Q S+ +++N +L+LE +E Q L+ + +LE T+ + E + + Q Q+
Sbjct: 1690 QMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQ 1749
Query: 124 VSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQ 183
+ + ++ +RM + + Q+ + + E++ DI++ + +Q
Sbjct: 1750 QKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKL----AQ 1805
Query: 184 VTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAI-EKLE 242
+ +AE+ K+ L+ LE N+R + +QE + L R + L +D A+ ++L+
Sbjct: 1806 TKRVLAAAEENSKMEQSNLEKLE----LNVRKL-QQELDQLNRDKLSLHNDISAMQQQLQ 1860
Query: 243 EEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHS-VLRVSQDLI---------- 291
E++ A+ + E+L N + D+ ++ H + + S R+ +D+
Sbjct: 1861 EKREAVNSLQEELAN-VQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQ 1919
Query: 292 -ETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVH 349
E E K + L + +E++ LK V + M Q+ + + + S K++ LKE+ H
Sbjct: 1920 KEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEES--KLETSKVTLKEQQH 1976
Score = 56.6 bits (135), Expect = 4e-08
Identities = 54/284 (19%), Positives = 122/284 (42%), Gaps = 36/284 (12%)
Query: 83 TNEFQQLQSKISLISEKLESTESILQEATSSMSL-----------MTQFEQEVSNLQDIM 131
+ E + LQ K + +KL T+ +L A + + + + +QE+ L
Sbjct: 1786 SKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDK 1845
Query: 132 HDIQNNEEVLTQRMQ-------SLNEKFQNITDFW---KRSLEEMNINTDIFKSEAKHIH 181
+ N+ + Q++Q SL E+ N+ D K+ L + D+ SE +
Sbjct: 1846 LSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQ 1905
Query: 182 SQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQ------LGSDT 235
++ N E + E++ + ++ ++ + EE+ L++ +Q L +
Sbjct: 1906 KDISEWANRFED--------CQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKER 1957
Query: 236 KAIE-KLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETE 294
++ E KLE + L + L +L+D + K+++ + + E + ++ + E
Sbjct: 1958 ESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLE 2017
Query: 295 KKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQ 338
K + Q+ E +++ E++ +QK + ++ D S+L+ Q
Sbjct: 2018 KTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQ 2061
Score = 48.5 bits (114), Expect = 1e-05
Identities = 64/306 (20%), Positives = 127/306 (41%), Gaps = 45/306 (14%)
Query: 66 SEKFAKVENQYQLLKLETNEFQQLQSKISL--------------ISEKLESTESILQEAT 111
SE ++E Q + T EF+QL+ I L +S +L+ + QEA
Sbjct: 454 SELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEAL 513
Query: 112 SSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTD 171
M + +QE++ Q + D+Q + + S + K ++ ++S +E + D
Sbjct: 514 DLELQMEKQKQEIAGKQKEIKDLQ----IAIDSLDSKDPKHSHMKA--QKSGKEQQL--D 565
Query: 172 IFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLE----DSTLRNIRTVKRQEEEDLLRV 227
I + + + S++ ++ +E TE +KDLE + + +K+ E + +
Sbjct: 566 IMNKQYQQLESRLDEILSRIAKE----TEEIKDLEEQLTEGQIAANEALKKDLEGVISGL 621
Query: 228 EEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPK----------VEECKTHLPTIE 277
+E LG+ + + E L E L +L++ E + E + L +E
Sbjct: 622 QEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELE 681
Query: 278 SAIHSVLRVSQDLIETEKKMEDLTMQM---FNMEDDMLKAVSEIMEMQKTLEGIQYDNSI 334
SA+ V+ L +T+ + ++ N+ D + E E++K Q + S
Sbjct: 682 SALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKE--ELEKVTRLTQLEQSA 739
Query: 335 LKMQNE 340
L+ + E
Sbjct: 740 LQAELE 745
Score = 44.3 bits (103), Expect = 2e-04
Identities = 60/285 (21%), Positives = 118/285 (41%), Gaps = 31/285 (10%)
Query: 71 KVENQYQLLKLETNEFQQLQSKISLISEK------LESTESILQEATSSMSLMTQFEQEV 124
++E Q Q + + E + LQ I + K +++ +S ++ M+ Q++Q
Sbjct: 518 QMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMN--KQYQQLE 575
Query: 125 SNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQV 184
S L +I+ I E + + L E + K+ LE + + K +Q
Sbjct: 576 SRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQA 635
Query: 185 TVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEE 244
+ E + L +RL ++E +R + E + E + + +E +E
Sbjct: 636 QNECRKLRDEKETLLQRLTEVEQ---------ERDQLEIVAMDAENMRKELAELESALQE 686
Query: 245 QHALFARDEDLTNKLSDYEPKVEECKTHLPTIES-----AIHSVLRVSQDLIETEKKMED 299
QH + A + LS YE ++E + +L E+ + V R++Q +E +
Sbjct: 687 QHEVNASLQQTQGDLSAYEAELE-ARLNLRDAEANQLKEELEKVTRLTQ--LEQSALQAE 743
Query: 300 LTMQMFNMEDDMLKAV------SEIMEMQKTLEGIQYDNSILKMQ 338
L + +++ + KA E E+ L+ +Q DN++LK Q
Sbjct: 744 LEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQ 788
Score = 43.9 bits (102), Expect = 2e-04
Identities = 55/247 (22%), Positives = 102/247 (41%), Gaps = 29/247 (11%)
Query: 121 EQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHI 180
E EVS L+DIM +++ + S + ++ +EE++ N D E K +
Sbjct: 1322 ENEVSRLEDIMQHLKSKKREERWMRASKRQS--------EKEMEELHHNIDDLLQEKKSL 1373
Query: 181 HSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEK 240
+V + ++ ++ KD D + ++ T E E L+ E + + + IEK
Sbjct: 1374 ECEVEELHRTVQKR-----QQQKDFIDGNVESLMT--ELEIEKSLKHHEDIVDEIECIEK 1426
Query: 241 -LEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMED 299
L + + L D L S+ E+ K +A+ + L++TE E+
Sbjct: 1427 TLLKRRSELREADRLLAEAESELSCTKEKTK-------NAVEKFTDAKRSLLQTESDAEE 1479
Query: 300 LTMQMFNMEDDMLKAVSEIMEMQKTLEGIQY----DNSILKMQNELDILKEKVHDFIAYS 355
L + +++KA ++ +Q + ++ ILK N+ I+ K DF S
Sbjct: 1480 LERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINK--IVAAKDSDFQCLS 1537
Query: 356 STGEKGT 362
EK T
Sbjct: 1538 KKKEKLT 1544
Score = 42.0 bits (97), Expect = 0.001
Identities = 56/286 (19%), Positives = 123/286 (43%), Gaps = 42/286 (14%)
Query: 70 AKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSS-------MSLMTQFEQ 122
+K +++ ++ +L N LQ K SL E E ++ + SLMT+ E
Sbjct: 1348 SKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEI 1407
Query: 123 EVS--NLQDIMHDIQNNEEVLTQRMQSLNE-----------------KFQNITDFW---K 160
E S + +DI+ +I+ E+ L +R L E K +N + + K
Sbjct: 1408 EKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAK 1467
Query: 161 RSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDLED------STLRNIR 214
RSL + T+ E + + V + A+Q+++ L KDLE L+ I
Sbjct: 1468 RSL----LQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEIN 1523
Query: 215 TVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLP 274
+ ++ D + ++ T+ ++KL+++ ++ L + E ++ + L
Sbjct: 1524 KIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELE 1583
Query: 275 TIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIME 320
++S + S Q++ ++++ ++ ++ M++A +++ E
Sbjct: 1584 KLKSQVTS---QQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQE 1626
Score = 35.4 bits (80), Expect = 0.085
Identities = 57/271 (21%), Positives = 112/271 (41%), Gaps = 50/271 (18%)
Query: 87 QQLQSKISLISEKLES-TESILQEATSSMSLMTQFE--QEVSNLQDIMHDIQNNEEVLTQ 143
++LQ +++L EKL + E Q ++ F+ Q + +Q + ++I +E L
Sbjct: 866 RKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQENL-- 923
Query: 144 RMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKL------ 197
+S+EE+ TD+ EA ++ Q+ E++ KL
Sbjct: 924 -----------------KSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQ 966
Query: 198 -----LTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARD 252
L + LK L+ + + T + +L ++QL S + K+ +E R
Sbjct: 967 EQVFGLDKELKKLK----KAVATSDKLATAELTIAKDQLKSLHGTVMKINQE------RA 1016
Query: 253 EDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDML 312
E+L + + K + L E+ I + Q+L+ + + L M+ +
Sbjct: 1017 EEL-QEAERFSRKAAQAARDLTRAEAEI----ELLQNLLRQKGEQFRLEMEKTGVGTGAN 1071
Query: 313 KAVSEIMEMQKTLEGIQYDNSILKMQNELDI 343
V EI ++ +T+E + I ++QN LD+
Sbjct: 1072 SQVLEIEKLNETME--RQRTEIARLQNVLDL 1100
Score = 30.4 bits (67), Expect = 2.7
Identities = 62/318 (19%), Positives = 128/318 (40%), Gaps = 35/318 (11%)
Query: 64 QQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSM-SLMTQFEQ 122
Q K E + + L+ E + L+ +S +L E L E + + +L + +
Sbjct: 1991 QVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADS 2050
Query: 123 EVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQ-NITDFWKRSLEEMNINTDIFKSEA---- 177
++ + + + +++ SL E + + K LE+ N+ I K A
Sbjct: 2051 MRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIEL 2110
Query: 178 ----KHIHSQ-VTVQINSAEQEIKLLTERLKDLEDSTLRNI------RTVKRQEEEDLLR 226
H ++ + ++N + E L +++ + +D R + RT+K + +++
Sbjct: 2111 VAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDE--- 2167
Query: 227 VEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTI--ESAIHSVL 284
+ L + + + +L + A+ R+E+L E ++E K +LP E L
Sbjct: 2168 IRTSLKNLNQFLPELPADLEAILERNENL-------EGELESLKENLPFTMNEGPFEEKL 2220
Query: 285 RVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGI-----QYDNSILKMQN 339
SQ I E + + +D LKA M K E + Q + ++ ++
Sbjct: 2221 NFSQVHIMDEHWRGEALREKLRHREDRLKAQLRHC-MSKQAEVLIKGKRQTEGTLHSLRR 2279
Query: 340 ELDILKEKVHDFIAYSST 357
++D L E V A S++
Sbjct: 2280 QVDALGELVTSTSADSAS 2297
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 56.2 bits (134), Expect = 5e-08
Identities = 71/344 (20%), Positives = 153/344 (44%), Gaps = 40/344 (11%)
Query: 62 VFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFE 121
+F+ + +V +Q + L+ E + LQ +IS ++E++ T LQEA + L+ E
Sbjct: 1485 LFKMRNAYEEVVDQLETLRREN---KNLQEEISDLTEQIAETGKNLQEAEKTKKLV---E 1538
Query: 122 QEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSE----A 177
QE S+LQ + +++ + E ++ + + + R + E + + K A
Sbjct: 1539 QEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAA 1598
Query: 178 KHIHSQVTVQINSAEQEIKLLTERLKDLED-------------STLRNIRTVKRQEEEDL 224
+ + S + +I S ++L + DL + T +++RTV+ Q ++
Sbjct: 1599 EALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQ 1658
Query: 225 LRVEEQLGSDTKAIEKL------------EEEQHALFARDEDLTNKLSDYEPKVEECKTH 272
L +++ L S+ E+L E E+ + + T +LS+ E +
Sbjct: 1659 LHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQ 1718
Query: 273 LPTIE--SAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQY 330
L + S I++ ++ D+ + + ++E+ + N E+ KA+++ M + L+ Q
Sbjct: 1719 LLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQD 1778
Query: 331 DNSIL-KMQNELD-ILKEKVHDFIAYSSTGEKGTLKE-YNIENK 371
++ L +M+ L+ +K+ H KG K+ +EN+
Sbjct: 1779 TSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENR 1822
Score = 55.8 bits (133), Expect = 6e-08
Identities = 59/312 (18%), Positives = 141/312 (45%), Gaps = 28/312 (8%)
Query: 64 QQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMT----- 118
Q SE AK E Q QL+ + +LQ++ +S ++E ES++ + T S +T
Sbjct: 1259 QFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEE 1318
Query: 119 ---QFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKS 175
Q E+E + H +Q++ + E+ Q +R+L + N +++
Sbjct: 1319 LKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEE-QEAKAELQRALSKANSEVAQWRT 1377
Query: 176 EAKHIHSQVTVQINSAEQEIKLLTERLKDLEDST---------LRNIRTVKRQEEEDLLR 226
+ + Q T ++ A+ K L +RL++ E++T L + + E EDL+R
Sbjct: 1378 KYETDAIQRTEELEEAK---KKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMR 1434
Query: 227 VEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRV 286
E+ + ++K + + A + KL + + ++E + ++ + + +
Sbjct: 1435 DLERSHTACATLDKKQRNFDKVLA---EWKQKLDESQAELEAAQKESRSLSTELFKMRNA 1491
Query: 287 SQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQ-NELDILK 345
+++++ ++E L + N+++++ +I E K L+ + +++ + ++L +
Sbjct: 1492 YEEVVD---QLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVAL 1548
Query: 346 EKVHDFIAYSST 357
E+V + + +
Sbjct: 1549 EEVEGSLEHEES 1560
Score = 45.4 bits (106), Expect = 8e-05
Identities = 49/279 (17%), Positives = 117/279 (41%), Gaps = 23/279 (8%)
Query: 79 LKLETNEFQQLQSKISLISEKLESTESILQEATSSMS----LMTQFEQEVSNLQDIMHDI 134
LK+ L++ I EKL+ E L + + + QF++++ LQ + ++
Sbjct: 1063 LKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEEL 1122
Query: 135 QNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQE 194
+ EE+ + +L K + R LEE++ + + QI ++
Sbjct: 1123 E--EEIEAEH--TLRAKIEKQRSDLARELEEIS-------ERLEEASGATSAQIEMNKKR 1171
Query: 195 IKLLTERLKDLEDSTLRN---IRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFAR 251
+ +DLE++TL++ T+++++ + + + EQ+ + + +KLE+E+ L
Sbjct: 1172 EAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKME 1231
Query: 252 DEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDM 311
+D+ + + + T+E + + + + + DL MQ ++
Sbjct: 1232 IDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDE---QQTQLIHDLNMQKARLQTQN 1288
Query: 312 LKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKVHD 350
+ + E + + Q S + +L+ LK ++ +
Sbjct: 1289 GELSHRVEEKESLIS--QLTKSKQALTQQLEELKRQMEE 1325
Score = 43.5 bits (101), Expect = 3e-04
Identities = 47/240 (19%), Positives = 109/240 (45%), Gaps = 17/240 (7%)
Query: 121 EQEVSNLQDIMHDIQNNEEVLTQ---RMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEA 177
E+E++ +++ D + +E L + R + L EK ++ ++ T+
Sbjct: 850 EKEMATMKE---DFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAE 906
Query: 178 KHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKA 237
+ + +I E ++K LTERL++ E+ + KR E+ ++ +
Sbjct: 907 ERCEGLIKSKI-LLEAKVKELTERLEEEEEMNSELVAK-KRNLEDKCSSLKRDIDDLELT 964
Query: 238 IEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSV---LRVSQD----L 290
+ K+E+E+HA + ++L+ +++ E + + +++ A L+V +D L
Sbjct: 965 LTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGL 1024
Query: 291 IETEKKMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEG--IQYDNSILKMQNELDILKEKV 348
I+ K+E T + + K +++ ++ LEG SI+ ++N+ ++EK+
Sbjct: 1025 IKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKL 1084
Score = 42.0 bits (97), Expect = 0.001
Identities = 50/260 (19%), Positives = 111/260 (42%), Gaps = 22/260 (8%)
Query: 80 KLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQ---FEQEVSNLQDIMHDIQN 136
+LE LQ K L + TE+++ L+ E +V L + + + +
Sbjct: 876 ELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEE 935
Query: 137 NEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQV---TVQINSAEQ 193
L + ++L +K ++ KR ++++ + + E ++V + ++ + E+
Sbjct: 936 MNSELVAKKRNLEDKCSSL----KRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEE 991
Query: 194 EIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDE 253
I LT+ K L+++ +Q +DL E+++ K KLE++ L E
Sbjct: 992 NISKLTKEKKSLQEA--------HQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLE 1043
Query: 254 DLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKME-DLTMQMFNMEDDML 312
+D E + + L + +I + Q + E KK E +L+ ++D+ +
Sbjct: 1044 QEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQV 1103
Query: 313 KAV---SEIMEMQKTLEGIQ 329
++ +I E+Q +E ++
Sbjct: 1104 HSLQFQKKIKELQARIEELE 1123
Score = 37.4 bits (85), Expect = 0.022
Identities = 40/175 (22%), Positives = 75/175 (42%), Gaps = 9/175 (5%)
Query: 70 AKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQD 129
A+VEN Q E+ ++ K I++ E + +E +S L + ++D
Sbjct: 1743 AEVENSIQ----ESRNAEEKAKKA--ITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1796
Query: 130 IMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLE-EMNINTDIFKSEAKHIHSQVTVQI 188
+ H + E++ + + +K +N + L+ E + K K+ +V
Sbjct: 1797 LQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKY-ERKVKEMT 1855
Query: 189 NSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEE 243
AE++ K + RL+DL D +++ KRQ EE + QL + +LEE
Sbjct: 1856 YQAEEDHKNIL-RLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEE 1909
Score = 35.0 bits (79), Expect = 0.11
Identities = 55/265 (20%), Positives = 113/265 (42%), Gaps = 38/265 (14%)
Query: 89 LQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQR---- 144
++ + L+ E+LE + L++ + L Q + S+ ++H QN + T++
Sbjct: 1678 VERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHS-QNTSLINTKKKLEA 1736
Query: 145 --------MQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIK 196
+++ ++ +N + K+++ + + + K E + + + + EQ +K
Sbjct: 1737 DIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVK 1795
Query: 197 LLTERLKDLEDSTLRN----IRTVKRQ--EEEDLLRVEEQLGSDT-KAIEKLE------- 242
L RL + E L+ I+ ++ + E E+ L VE++ G++ K K E
Sbjct: 1796 DLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMT 1855
Query: 243 ---EEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVL----RVSQDLIETEK 295
EE H R +DL +KL + KV+ K E ++ L RV +L E +
Sbjct: 1856 YQAEEDHKNILRLQDLVDKL---QAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAE 1912
Query: 296 KMEDLTMQMFNMEDDMLKAVSEIME 320
+ + Q+ + S+ ME
Sbjct: 1913 RADIAESQVNKLRAKSRDVGSQKME 1937
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 55.8 bits (133), Expect = 6e-08
Identities = 58/275 (21%), Positives = 124/275 (45%), Gaps = 37/275 (13%)
Query: 79 LKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMT----QFEQEVSNL---QDIM 131
LK E +L K+S +K++ ++ +QE +++ +++ ++ L Q+I+
Sbjct: 1220 LKTIMKENTELVQKLSNYEQKIKESKKHVQETRKQNMILSDEAIKYKDKIKTLEKNQEIL 1279
Query: 132 HDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSA 191
D N V+ + + N K Q++ K+S+E++ D+ A S+V + +N A
Sbjct: 1280 DDTAKNLRVMLESEREQNVKNQDLISENKKSIEKLK---DVISMNASEF-SEVQIALNEA 1335
Query: 192 ---EQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHAL 248
E+++K R+++ E++ L+ + +QE ED ++ +L K+ EK +++
Sbjct: 1336 KLSEEKVKSECHRVQE-ENARLKKKKEQLQQEIEDWSKLHAELSEQIKSFEKSQKDLEVA 1394
Query: 249 FARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNME 308
+D N L++ C T L +E S E + K + + ++ N E
Sbjct: 1395 LTHKDDNINALTN-------CITQLNLLECESES---------EGQNKGGNDSDELANGE 1438
Query: 309 ------DDMLKAVSEIMEMQKTLEGIQYDNSILKM 337
+ M + ++M++ +T I LK+
Sbjct: 1439 VGGDRNEKMKNQIKQMMDVSRTQTAISVVEEDLKL 1473
Score = 46.6 bits (109), Expect = 4e-05
Identities = 52/249 (20%), Positives = 109/249 (43%), Gaps = 38/249 (15%)
Query: 146 QSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLKDL 205
Q ++EK + I +++++ K KH+ + +++ IK +++K L
Sbjct: 1214 QQISEKLKTIMKENTELVQKLSNYEQKIKESKKHVQETRKQNMILSDEAIKY-KDKIKTL 1272
Query: 206 E------DSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKL 259
E D T +N+R + E E ++ ++ + + K+IEKL++ + + + ++
Sbjct: 1273 EKNQEILDDTAKNLRVMLESEREQNVKNQDLISENKKSIEKLKD----VISMN---ASEF 1325
Query: 260 SDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIM 319
S+ + + E K ++S H RV ++ +KK E L ++ +D K +E+
Sbjct: 1326 SEVQIALNEAKLSEEKVKSECH---RVQEENARLKKKKEQLQQEI----EDWSKLHAELS 1378
Query: 320 EMQKTLEGIQYD------------NSILKMQNELDILKEKVHDFIAYSSTGEKGTLKEYN 367
E K+ E Q D N++ +L++L+ + + S KG
Sbjct: 1379 EQIKSFEKSQKDLEVALTHKDDNINALTNCITQLNLLECE-----SESEGQNKGGNDSDE 1433
Query: 368 IENKGIGGD 376
+ N +GGD
Sbjct: 1434 LANGEVGGD 1442
Score = 45.4 bits (106), Expect = 8e-05
Identities = 33/152 (21%), Positives = 76/152 (50%), Gaps = 10/152 (6%)
Query: 71 KVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDI 130
K++NQ + + + + Q+ IS++ E L+ + L+ +S+S E +V L+D
Sbjct: 1446 KMKNQIKQMM----DVSRTQTAISVVEEDLKLLQLKLR---ASVSTKCNLEDQVKKLEDD 1498
Query: 131 MHDIQNNEEVLTQRMQSLNEKFQNITDFWKR---SLEEMNINTDIFKSEAKHIHSQVTVQ 187
+ +Q + L ++L +K + + + +++ +L++ + + E +H S +
Sbjct: 1499 RNSLQAAKAGLEDECKTLRQKVEILNELYQQKEMALQKKLSQEEYERQEREHRLSAADEK 1558
Query: 188 INSAEQEIKLLTERLKDLEDSTLRNIRTVKRQ 219
SA +E+K R++++ED + R+ K Q
Sbjct: 1559 AVSAAEEVKTYKRRIEEMEDELQKTERSFKNQ 1590
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 55.8 bits (133), Expect = 6e-08
Identities = 71/325 (21%), Positives = 137/325 (42%), Gaps = 53/325 (16%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSLMTQFEQEV 124
+S K + + + Q +L+ Q+ S++S + E LE IL+E + S E+ V
Sbjct: 768 ESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEAS-----EEAV 822
Query: 125 S---NLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIH 181
S ++Q+ ++ + EE L + +N+ D + E+ + K++ K +
Sbjct: 823 SVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEN 882
Query: 182 SQVTVQINSAEQEIKL------LTERLKDLEDSTLR------NIRTVKRQEEEDLLRVEE 229
+ S + +L L + +D+E+ L+ N +++ E+ ++ E+
Sbjct: 883 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQ 942
Query: 230 QLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHS-----VL 284
S +A +K EEE+ L + DL K+ + +E K S + +
Sbjct: 943 ---SQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 999
Query: 285 RVSQDLIETEKKMEDLT---------MQMFNMEDDMLKA---------VSEIMEMQKT-- 324
+ + L++TE K++ ++ + D KA + E M +KT
Sbjct: 1000 NLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTET 1059
Query: 325 ---LEGIQYDNSILKMQNELDILKE 346
LE + N+ K+QNELD LKE
Sbjct: 1060 LASLEDTKQTNA--KLQNELDTLKE 1082
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/299 (22%), Positives = 130/299 (43%), Gaps = 21/299 (7%)
Query: 85 EFQQLQSKI-SLISEKLESTESILQEATSSMSLMTQFEQEVSNLQDIMHDIQNNE----- 138
E + L++K+ +I EK S E+I + + +Q + ++D ++ +Q E
Sbjct: 645 EMEALRAKLMKVIKEKENSLEAIRSKLDKAE------DQHLVEMEDTLNKLQEAEIKVKE 698
Query: 139 -EVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFK---SEAKHIHSQVTVQINSAEQE 194
EVL + + N T K + EE ++ D + SE K ++ Q+ +AE++
Sbjct: 699 LEVLQAKCNEQTKVIDNFTSQLKAT-EEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQ 757
Query: 195 IKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDED 254
IK L E K+ E S +I + E L ++E L ++ E LE+E L + +
Sbjct: 758 IKHL-EIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAE 816
Query: 255 LTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKA 314
+ + + ++E L E + + + L E ME + E+ ++KA
Sbjct: 817 ASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKA 876
Query: 315 VSEIMEMQKTLEGIQYDNS--ILKMQNELDILKEKVHDF-IAYSSTGEKGTLKEYNIEN 370
++ + + DNS + KM +EL + + V + + + E + + +IE+
Sbjct: 877 KEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIED 935
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/247 (21%), Positives = 115/247 (46%), Gaps = 33/247 (13%)
Query: 84 NEFQQLQSKISLISEKLESTESILQEATSSMSLMTQF----EQEVSNLQDIMHDIQNNEE 139
+E ++L+ ++ ++++ E +S S +T+ E +++NLQ+ + ++ +E
Sbjct: 742 SEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKE 801
Query: 140 VLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLT 199
L + +Q L EKF ++ E +++ + ++ K +H Q Q N +++ L
Sbjct: 802 TLEKELQILKEKFAEASE------EAVSVQRSMQETVNK-LH-QKEEQFNMLSSDLEKLR 853
Query: 200 ERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKL 259
E L D+E K + EE L++ +E+L +D I K+ + + + + ++L
Sbjct: 854 ENLADMEAKFRE-----KDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTK---MNDEL 905
Query: 260 SDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMEDDMLKAVSEIM 319
E VEE + L + +++ +K +ED+T++ E +A +
Sbjct: 906 RLKERDVEELQLKL----------TKANENASFLQKSIEDMTVK---AEQSQQEAAKKHE 952
Query: 320 EMQKTLE 326
E +K LE
Sbjct: 953 EEKKELE 959
Score = 46.6 bits (109), Expect = 4e-05
Identities = 52/276 (18%), Positives = 113/276 (40%), Gaps = 25/276 (9%)
Query: 89 LQSKISLISEKLESTESILQEATSSM-----SLMTQFEQEVSNLQDIMHDIQNNEEVLTQ 143
L +IS + EKLE T + Q +S+ + ++E+ L + E L
Sbjct: 502 LLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKS 561
Query: 144 RMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQINSAEQEIKLLTERLK 203
+++ N++ ++ WK LE + E K S+ + E+K E+++
Sbjct: 562 KLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMR 621
Query: 204 DLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHALFA------------- 250
+ N++ +Q+ E +E K ++ ++E++++L A
Sbjct: 622 LDYQHEIENLQN--QQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHL 679
Query: 251 -RDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNMED 309
ED NKL + E KV+E L +++ + +V + K E+ + + +
Sbjct: 680 VEMEDTLNKLQEAEIKVKE----LEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRK 735
Query: 310 DMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILK 345
+ SE+ ++++ LE + L+++ + K
Sbjct: 736 ASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSK 771
Score = 45.1 bits (105), Expect = 1e-04
Identities = 53/256 (20%), Positives = 113/256 (44%), Gaps = 33/256 (12%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLISEKLESTESILQE-----ATSSMSLMTQFEQEVSNL 127
++Q + K E ++L+ K+S + +K+E++ + QE ++ T+ E+ + NL
Sbjct: 942 QSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1001
Query: 128 QDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAKHIHSQVTVQ 187
Q + D ++ +++ E+ + + LEE+ D K+ ++ +Q
Sbjct: 1002 QKTLLDTED-------KLKGAREENSGLL----QELEELRKQADKAKAAQT---AEDAMQ 1047
Query: 188 INSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAIEKLEEEQHA 247
I EQ K TE L LED+ N K Q E D L+ ++ K +E+L + +
Sbjct: 1048 I--MEQMTKEKTETLASLEDTKQTN---AKLQNELDTLK-----ENNLKNVEELNKSKEL 1097
Query: 248 LFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEKKMEDLTMQMFNM 307
L ++ K+ ++ ++E K + ++ + L E + D +
Sbjct: 1098 LTVENQ----KMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKL 1153
Query: 308 EDDMLKAVSEIMEMQK 323
E++ ++++EM+K
Sbjct: 1154 EEERSVLNNQLLEMKK 1169
Score = 30.0 bits (66), Expect = 3.6
Identities = 47/256 (18%), Positives = 105/256 (41%), Gaps = 24/256 (9%)
Query: 63 FQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEA--TSSMSLMTQF 120
FQ K+ +++ K+ ++K + + + +T + L+ + SS+S M+
Sbjct: 263 FQCQPKYGLFAPVHKVTKIGFPSTTPAKAKANAVRRVMATTSASLKRSPSASSLSSMSSV 322
Query: 121 EQEVSN-------LQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFW-KRSLEEMNI---N 169
VS+ L + T ++L EK Q+I +R LE +
Sbjct: 323 ASSVSSRPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKAT 382
Query: 170 TDIFKSE-----AKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDL 224
+ + + E A+ H Q +++ + +++ + E + L + KR+ E+
Sbjct: 383 SHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQ 442
Query: 225 LRVEEQLGSDTKAIEKLEEEQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESA--IHS 282
RVEE+ + E+ + ++DL ++ + V E + L + + A +
Sbjct: 443 FRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQE----VAELRRRLESNKPAGDVDM 498
Query: 283 VLRVSQDLIETEKKME 298
L + Q++ ++K+E
Sbjct: 499 SLSLLQEISSLQEKLE 514
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,711,249
Number of Sequences: 37866
Number of extensions: 568782
Number of successful extensions: 6051
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 735
Number of HSP's that attempted gapping in prelim test: 3773
Number of HSP's gapped (non-prelim): 2203
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.