Guide to the Human Genome
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Search of human proteins with 239758027

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239758027 PREDICTED: similar to LIM and senescent cell
antigen-like domains 1 [Homo sapiens]
         (116 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239758027 PREDICTED: similar to LIM and senescent cell antige...   262   5e-71
gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo ...   208   6e-55
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ...   208   6e-55
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo...   180   2e-46
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo...   180   2e-46
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo...   180   2e-46
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor...   180   2e-46
gi|170932518 paxillin isoform 3 [Homo sapiens]                         60   4e-10
gi|170932516 paxillin isoform 2 [Homo sapiens]                         60   4e-10
gi|170932514 paxillin isoform 1 [Homo sapiens]                         60   4e-10
gi|221316659 leupaxin isoform 1 [Homo sapiens]                         60   4e-10
gi|4758670 leupaxin isoform 2 [Homo sapiens]                           60   4e-10
gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]     57   3e-09
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]     57   3e-09
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]     57   3e-09
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]    54   3e-08
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]    54   3e-08
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]    54   3e-08
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]    54   3e-08
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]    54   3e-08
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]    54   3e-08
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]     54   3e-08
gi|54112385 four and a half LIM domains 3 [Homo sapiens]               54   3e-08
gi|109638745 transforming growth factor beta 1 induced transcrip...    54   3e-08
gi|21361591 transforming growth factor beta 1 induced transcript...    54   3e-08
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]             52   8e-08
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              52   8e-08
gi|87159836 four and a half LIM domains 2 [Homo sapiens]               52   1e-07
gi|87159834 four and a half LIM domains 2 [Homo sapiens]               52   1e-07
gi|42403575 four and a half LIM domains 2 [Homo sapiens]               52   1e-07

>gi|239758027 PREDICTED: similar to LIM and senescent cell
           antigen-like domains 1 [Homo sapiens]
          Length = 116

 Score =  262 bits (669), Expect = 5e-71
 Identities = 116/116 (100%), Positives = 116/116 (100%)

Query: 1   MDLLARWPLHWLLIPLPGFQRLKKLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF 60
           MDLLARWPLHWLLIPLPGFQRLKKLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF
Sbjct: 1   MDLLARWPLHWLLIPLPGFQRLKKLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF 60

Query: 61  VKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
           VKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCG
Sbjct: 61  VKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116


>gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo
           sapiens]
          Length = 248

 Score =  208 bits (530), Expect = 6e-55
 Identities = 91/91 (100%), Positives = 91/91 (100%)

Query: 26  GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 85
           GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI
Sbjct: 137 GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 196

Query: 86  CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
           CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG
Sbjct: 197 CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 227



 Score = 34.3 bits (77), Expect = 0.022
 Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 5/83 (6%)

Query: 33  VIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAI 92
           ++ +    +H +CF C  C +   +  F +  GR  C   H+ +    L    C +C   
Sbjct: 85  IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE--HDFQM---LFAPCCHQCGEF 139

Query: 93  IDEQPLIFKNDPYHPDHFNCANC 115
           I  + +   N+ +HP+ F C  C
Sbjct: 140 IIGRVIKAMNNSWHPECFRCDLC 162


>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 325

 Score =  208 bits (530), Expect = 6e-55
 Identities = 91/91 (100%), Positives = 91/91 (100%)

Query: 26  GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 85
           GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI
Sbjct: 75  GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 134

Query: 86  CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
           CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG
Sbjct: 135 CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 165



 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I GRV+ AM   WH E F C  C++        +  G   C   +N+     L   +C  
Sbjct: 200 IEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQ-----LFGDVCFH 254

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C+ +I+   +   N  +  + F C+ C
Sbjct: 255 CNRVIEGDVVSALNKAWCVNCFACSTC 281



 Score = 35.0 bits (79), Expect = 0.013
 Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 5/84 (5%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 91
           +++ +    +H +CF C  C +   +  F +  GR  C   H+ +    L    C +C  
Sbjct: 22  KIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE--HDFQM---LFAPCCHQCGE 76

Query: 92  IIDEQPLIFKNDPYHPDHFNCANC 115
            I  + +   N+ +HP+ F C  C
Sbjct: 77  FIIGRVIKAMNNSWHPECFRCDLC 100



 Score = 32.3 bits (72), Expect = 0.083
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 75
           I G V+ A+N +W   CF C  C   L     FV+   + +C+ C+ +
Sbjct: 259 IEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306


>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
           1 [Homo sapiens]
          Length = 363

 Score =  180 bits (456), Expect = 2e-46
 Identities = 74/91 (81%), Positives = 84/91 (92%)

Query: 26  GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 85
           GEFIIGRVIKAMNN+WHP CFRC+LC   LAD+GFVKNAGRHLCRPCHNREKA+GLGKYI
Sbjct: 102 GEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYI 161

Query: 86  CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
           CQ+CH +IDEQPL+F++D YHPDHFNC +CG
Sbjct: 162 CQRCHLVIDEQPLMFRSDAYHPDHFNCTHCG 192



 Score = 38.9 bits (89), Expect = 9e-04
 Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I GRV+ A+   WH E F C  C++        +  G   C   +N+     L   +C  
Sbjct: 227 IEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQ-----LFGDVCYN 281

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C  +I+   +   N  +    F+C+ C
Sbjct: 282 CSHVIEGDVVSALNKAWCVSCFSCSTC 308



 Score = 32.3 bits (72), Expect = 0.083
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 75
           I G V+ A+N +W   CF C  C   L     FV+   + +C+ C+ +
Sbjct: 286 IEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333


>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
           5 [Homo sapiens]
          Length = 336

 Score =  180 bits (456), Expect = 2e-46
 Identities = 74/91 (81%), Positives = 84/91 (92%)

Query: 26  GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 85
           GEFIIGRVIKAMNN+WHP CFRC+LC   LAD+GFVKNAGRHLCRPCHNREKA+GLGKYI
Sbjct: 75  GEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYI 134

Query: 86  CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
           CQ+CH +IDEQPL+F++D YHPDHFNC +CG
Sbjct: 135 CQRCHLVIDEQPLMFRSDAYHPDHFNCTHCG 165



 Score = 38.9 bits (89), Expect = 9e-04
 Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I GRV+ A+   WH E F C  C++        +  G   C   +N+     L   +C  
Sbjct: 200 IEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQ-----LFGDVCYN 254

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C  +I+   +   N  +    F+C+ C
Sbjct: 255 CSHVIEGDVVSALNKAWCVSCFSCSTC 281



 Score = 32.3 bits (72), Expect = 0.083
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 75
           I G V+ A+N +W   CF C  C   L     FV+   + +C+ C+ +
Sbjct: 259 IEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306


>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
           3 [Homo sapiens]
          Length = 341

 Score =  180 bits (456), Expect = 2e-46
 Identities = 74/91 (81%), Positives = 84/91 (92%)

Query: 26  GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 85
           GEFIIGRVIKAMNN+WHP CFRC+LC   LAD+GFVKNAGRHLCRPCHNREKA+GLGKYI
Sbjct: 80  GEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYI 139

Query: 86  CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
           CQ+CH +IDEQPL+F++D YHPDHFNC +CG
Sbjct: 140 CQRCHLVIDEQPLMFRSDAYHPDHFNCTHCG 170



 Score = 38.9 bits (89), Expect = 9e-04
 Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I GRV+ A+   WH E F C  C++        +  G   C   +N+     L   +C  
Sbjct: 205 IEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQ-----LFGDVCYN 259

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C  +I+   +   N  +    F+C+ C
Sbjct: 260 CSHVIEGDVVSALNKAWCVSCFSCSTC 286



 Score = 32.3 bits (72), Expect = 0.083
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 75
           I G V+ A+N +W   CF C  C   L     FV+   + +C+ C+ +
Sbjct: 264 IEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311


>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
           [Homo sapiens]
          Length = 365

 Score =  180 bits (456), Expect = 2e-46
 Identities = 74/91 (81%), Positives = 84/91 (92%)

Query: 26  GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 85
           GEFIIGRVIKAMNN+WHP CFRC+LC   LAD+GFVKNAGRHLCRPCHNREKA+GLGKYI
Sbjct: 104 GEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYI 163

Query: 86  CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
           CQ+CH +IDEQPL+F++D YHPDHFNC +CG
Sbjct: 164 CQRCHLVIDEQPLMFRSDAYHPDHFNCTHCG 194



 Score = 38.9 bits (89), Expect = 9e-04
 Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I GRV+ A+   WH E F C  C++        +  G   C   +N+     L   +C  
Sbjct: 229 IEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQ-----LFGDVCYN 283

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C  +I+   +   N  +    F+C+ C
Sbjct: 284 CSHVIEGDVVSALNKAWCVSCFSCSTC 310



 Score = 32.3 bits (72), Expect = 0.083
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 75
           I G V+ A+N +W   CF C  C   L     FV+   + +C+ C+ +
Sbjct: 288 IEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score = 60.1 bits (144), Expect = 4e-10
 Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 7/89 (7%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARGLGKYICQ 87
           I G+V+ AM  +WHPE F C  CQE +    F +  G+  C +  HN    R      C 
Sbjct: 198 IAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR------CY 251

Query: 88  KCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
            C+  I ++ +   +  +HP+HF CA CG
Sbjct: 252 YCNGPILDKVVTALDRTWHPEHFFCAQCG 280



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I+   I A+N  WHPECF C  C     +  F ++ G+  C   H  E+   L    C  
Sbjct: 316 ILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE-VHYHERRGSL----CSG 370

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C   I  + +      +HP+HF CA C
Sbjct: 371 CQKPITGRCITAMAKKFHPEHFVCAFC 397



 Score = 44.3 bits (103), Expect = 2e-05
 Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I+ +V+ A++ +WHPE F C  C       GF +  G+  CR  +    A       C  
Sbjct: 257 ILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK-----CGG 311

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C   I E  +   N  +HP+ F C  C
Sbjct: 312 CARAILENYISALNTLWHPECFVCREC 338



 Score = 31.6 bits (70), Expect = 0.14
 Identities = 16/44 (36%), Positives = 21/44 (47%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           I GR I AM   +HPE F C  C + L    F +   +  C+ C
Sbjct: 375 ITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 418



 Score = 28.9 bits (63), Expect = 0.91
 Identities = 11/35 (31%), Positives = 17/35 (48%)

Query: 81  LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 115
           + K +C  C   I  Q +      +HP+HF C +C
Sbjct: 186 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHC 220


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score = 60.1 bits (144), Expect = 4e-10
 Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 7/89 (7%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARGLGKYICQ 87
           I G+V+ AM  +WHPE F C  CQE +    F +  G+  C +  HN    R      C 
Sbjct: 331 IAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR------CY 384

Query: 88  KCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
            C+  I ++ +   +  +HP+HF CA CG
Sbjct: 385 YCNGPILDKVVTALDRTWHPEHFFCAQCG 413



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I+   I A+N  WHPECF C  C     +  F ++ G+  C   H  E+   L    C  
Sbjct: 449 ILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE-VHYHERRGSL----CSG 503

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C   I  + +      +HP+HF CA C
Sbjct: 504 CQKPITGRCITAMAKKFHPEHFVCAFC 530



 Score = 44.3 bits (103), Expect = 2e-05
 Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I+ +V+ A++ +WHPE F C  C       GF +  G+  CR  +    A       C  
Sbjct: 390 ILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK-----CGG 444

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C   I E  +   N  +HP+ F C  C
Sbjct: 445 CARAILENYISALNTLWHPECFVCREC 471



 Score = 31.6 bits (70), Expect = 0.14
 Identities = 16/44 (36%), Positives = 21/44 (47%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           I GR I AM   +HPE F C  C + L    F +   +  C+ C
Sbjct: 508 ITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 551



 Score = 28.9 bits (63), Expect = 0.91
 Identities = 11/35 (31%), Positives = 17/35 (48%)

Query: 81  LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 115
           + K +C  C   I  Q +      +HP+HF C +C
Sbjct: 319 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHC 353


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score = 60.1 bits (144), Expect = 4e-10
 Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 7/89 (7%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARGLGKYICQ 87
           I G+V+ AM  +WHPE F C  CQE +    F +  G+  C +  HN    R      C 
Sbjct: 365 IAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR------CY 418

Query: 88  KCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
            C+  I ++ +   +  +HP+HF CA CG
Sbjct: 419 YCNGPILDKVVTALDRTWHPEHFFCAQCG 447



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I+   I A+N  WHPECF C  C     +  F ++ G+  C   H  E+   L    C  
Sbjct: 483 ILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE-VHYHERRGSL----CSG 537

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C   I  + +      +HP+HF CA C
Sbjct: 538 CQKPITGRCITAMAKKFHPEHFVCAFC 564



 Score = 44.3 bits (103), Expect = 2e-05
 Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I+ +V+ A++ +WHPE F C  C       GF +  G+  CR  +    A       C  
Sbjct: 424 ILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK-----CGG 478

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C   I E  +   N  +HP+ F C  C
Sbjct: 479 CARAILENYISALNTLWHPECFVCREC 505



 Score = 31.6 bits (70), Expect = 0.14
 Identities = 16/44 (36%), Positives = 21/44 (47%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           I GR I AM   +HPE F C  C + L    F +   +  C+ C
Sbjct: 542 ITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 585



 Score = 28.9 bits (63), Expect = 0.91
 Identities = 11/35 (31%), Positives = 17/35 (48%)

Query: 81  LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 115
           + K +C  C   I  Q +      +HP+HF C +C
Sbjct: 353 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHC 387


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score = 60.1 bits (144), Expect = 4e-10
 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 5/88 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I G+VI A+  SWHPE F C  C+E +    F + +G   C   +++     L    C  
Sbjct: 164 IAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----LFSPRCAY 218

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANCG 116
           C A I ++ L   N  +HP+HF C++CG
Sbjct: 219 CAAPILDKVLTAMNQTWHPEHFFCSHCG 246



 Score = 48.9 bits (115), Expect = 9e-07
 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I+ +V+ AMN +WHPE F C  C EV    GF +   +  C     R+    +    C  
Sbjct: 223 ILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLAMFSPKCGG 277

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C+  + E  L   +  +HP+ F C +C
Sbjct: 278 CNRPVLENYLSAMDTVWHPECFVCGDC 304



 Score = 48.1 bits (113), Expect = 1e-06
 Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           ++   + AM+  WHPECF C  C    +   F +  GR  C   ++  +       +C  
Sbjct: 282 VLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT-----LCHG 336

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C   I  + +      +HP+HF CA C
Sbjct: 337 CGQPITGRCISAMGYKFHPEHFVCAFC 363



 Score = 38.9 bits (89), Expect = 9e-04
 Identities = 19/50 (38%), Positives = 26/50 (52%)

Query: 26  GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 75
           G+ I GR I AM   +HPE F C  C   L+   F +   +  C+PC N+
Sbjct: 338 GQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 387



 Score = 25.8 bits (55), Expect = 7.7
 Identities = 9/30 (30%), Positives = 14/30 (46%)

Query: 86  CQKCHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C  C   I  + +      +HP+HF C +C
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHC 186


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score = 60.1 bits (144), Expect = 4e-10
 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 5/88 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I G+VI A+  SWHPE F C  C+E +    F + +G   C   +++     L    C  
Sbjct: 159 IAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----LFSPRCAY 213

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANCG 116
           C A I ++ L   N  +HP+HF C++CG
Sbjct: 214 CAAPILDKVLTAMNQTWHPEHFFCSHCG 241



 Score = 48.9 bits (115), Expect = 9e-07
 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I+ +V+ AMN +WHPE F C  C EV    GF +   +  C     R+    +    C  
Sbjct: 218 ILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLAMFSPKCGG 272

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C+  + E  L   +  +HP+ F C +C
Sbjct: 273 CNRPVLENYLSAMDTVWHPECFVCGDC 299



 Score = 48.1 bits (113), Expect = 1e-06
 Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           ++   + AM+  WHPECF C  C    +   F +  GR  C   ++  +       +C  
Sbjct: 277 VLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT-----LCHG 331

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C   I  + +      +HP+HF CA C
Sbjct: 332 CGQPITGRCISAMGYKFHPEHFVCAFC 358



 Score = 38.9 bits (89), Expect = 9e-04
 Identities = 19/50 (38%), Positives = 26/50 (52%)

Query: 26  GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 75
           G+ I GR I AM   +HPE F C  C   L+   F +   +  C+PC N+
Sbjct: 333 GQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 382



 Score = 25.8 bits (55), Expect = 7.7
 Identities = 9/30 (30%), Positives = 14/30 (46%)

Query: 86  CQKCHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C  C   I  + +      +HP+HF C +C
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHC 181


>gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]
          Length = 276

 Score = 57.0 bits (136), Expect = 3e-09
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 34  IKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII 93
           ++AM   +H +CF C  C+  LA   F +  GR LC PC+     R      C KC  ++
Sbjct: 100 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER------CGKCGEVV 153

Query: 94  DEQPLIFKNDPYHPDHFNCANC 115
            +  +      +HP  F C  C
Sbjct: 154 RDHIIRALGQAFHPSCFTCVTC 175



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 14/41 (34%), Positives = 22/41 (53%)

Query: 20  QRLKKLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF 60
           +R  K GE +   +I+A+  ++HP CF C  C   + D  F
Sbjct: 144 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 184



 Score = 35.8 bits (81), Expect = 0.007
 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 4/51 (7%)

Query: 34  IKAMNNSWHPECFRCDLCQEVLA----DIGFVKNAGRHLCRPCHNREKARG 80
           I+ M  ++H  C+RC+ C+ +L+    D G         C+PCH +  A G
Sbjct: 224 IECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAG 274


>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
          Length = 374

 Score = 57.0 bits (136), Expect = 3e-09
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 34  IKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII 93
           ++AM   +H +CF C  C+  LA   F +  GR LC PC+     R      C KC  ++
Sbjct: 197 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER------CGKCGEVV 250

Query: 94  DEQPLIFKNDPYHPDHFNCANC 115
            +  +      +HP  F C  C
Sbjct: 251 RDHIIRALGQAFHPSCFTCVTC 272



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 14/41 (34%), Positives = 22/41 (53%)

Query: 20  QRLKKLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF 60
           +R  K GE +   +I+A+  ++HP CF C  C   + D  F
Sbjct: 241 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281


>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
          Length = 373

 Score = 57.0 bits (136), Expect = 3e-09
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 34  IKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII 93
           ++AM   +H +CF C  C+  LA   F +  GR LC PC+     R      C KC  ++
Sbjct: 197 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER------CGKCGEVV 250

Query: 94  DEQPLIFKNDPYHPDHFNCANC 115
            +  +      +HP  F C  C
Sbjct: 251 RDHIIRALGQAFHPSCFTCVTC 272



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 14/41 (34%), Positives = 22/41 (53%)

Query: 20  QRLKKLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF 60
           +R  K GE +   +I+A+  ++HP CF C  C   + D  F
Sbjct: 241 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281



 Score = 35.8 bits (81), Expect = 0.007
 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 4/51 (7%)

Query: 34  IKAMNNSWHPECFRCDLCQEVLA----DIGFVKNAGRHLCRPCHNREKARG 80
           I+ M  ++H  C+RC+ C+ +L+    D G         C+PCH +  A G
Sbjct: 321 IECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAG 371


>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
          Length = 194

 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 9/81 (11%)

Query: 38  NNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIID 94
           N  WH  CFRC  C   LA+  FV    + LC  C  RE   K +G  K I      +  
Sbjct: 58  NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAG 111

Query: 95  EQPLIFKNDPYHPDHFNCANC 115
           +Q + +K   +H D F C+NC
Sbjct: 112 DQNVEYKGTVWHKDCFTCSNC 132



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%)

Query: 44  ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 101
           E F C  C++ L    +V+  G H C  C ++  A       C +C   I  D + + +K
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57

Query: 102 NDPYHPDHFNCANC 115
           N  +H   F CA C
Sbjct: 58  NRFWHDTCFRCAKC 71



 Score = 36.2 bits (82), Expect = 0.006
 Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 5/58 (8%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPL 98
           WH +CF C  C++V+    F        C  CH  + A+      C KC+  + + P+
Sbjct: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKGLVKAPV 174


>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 9/81 (11%)

Query: 38  NNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIID 94
           N  WH  CFRC  C   LA+  FV    + LC  C  RE   K +G  K I      +  
Sbjct: 58  NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAG 111

Query: 95  EQPLIFKNDPYHPDHFNCANC 115
           +Q + +K   +H D F C+NC
Sbjct: 112 DQNVEYKGTVWHKDCFTCSNC 132



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIF 100
           WH +CF C  C++V+    F        C  CH  + A+      C KC+  I    + +
Sbjct: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITY 176

Query: 101 KNDPYHPDHFNCANC 115
           ++ P+H D F C  C
Sbjct: 177 QDQPWHADCFVCVTC 191



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%)

Query: 44  ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 101
           E F C  C++ L    +V+  G H C  C ++  A       C +C   I  D + + +K
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57

Query: 102 NDPYHPDHFNCANC 115
           N  +H   F CA C
Sbjct: 58  NRFWHDTCFRCAKC 71



 Score = 33.1 bits (74), Expect = 0.048
 Identities = 22/97 (22%), Positives = 35/97 (36%), Gaps = 10/97 (10%)

Query: 24  KLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGK 83
           K  + I    I   +  WH +CF C  C + LA   F     ++ C  C+    A+    
Sbjct: 164 KCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK--- 220

Query: 84  YICQKCHAII-----DEQPLIFKNDPYHPDHFNCANC 115
             C  C   I         + ++   +H   F+C  C
Sbjct: 221 --CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKC 255



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 14/40 (35%), Positives = 18/40 (45%)

Query: 33  VIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           V+     SWH  CF C  C   LA+  FV +  +  C  C
Sbjct: 237 VVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276


>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
          Length = 323

 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 9/81 (11%)

Query: 38  NNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIID 94
           N  WH  CFRC  C   LA+  FV    + LC  C  RE   K +G  K I      +  
Sbjct: 58  NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAG 111

Query: 95  EQPLIFKNDPYHPDHFNCANC 115
           +Q + +K   +H D F C+NC
Sbjct: 112 DQNVEYKGTVWHKDCFTCSNC 132



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIF 100
           WH +CF C  C++V+    F        C  CH  + A+      C KC+  I    + +
Sbjct: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITY 176

Query: 101 KNDPYHPDHFNCANC 115
           ++ P+H D F C  C
Sbjct: 177 QDQPWHADCFVCVTC 191



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%)

Query: 44  ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 101
           E F C  C++ L    +V+  G H C  C ++  A       C +C   I  D + + +K
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57

Query: 102 NDPYHPDHFNCANC 115
           N  +H   F CA C
Sbjct: 58  NRFWHDTCFRCAKC 71



 Score = 31.2 bits (69), Expect = 0.18
 Identities = 16/66 (24%), Positives = 26/66 (39%), Gaps = 8/66 (12%)

Query: 24  KLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGK 83
           K  + I    I   +  WH +CF C  C + LA   F     ++ C  C+          
Sbjct: 164 KCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK--------N 215

Query: 84  YICQKC 89
           ++ +KC
Sbjct: 216 FVAKKC 221


>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 9/81 (11%)

Query: 38  NNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIID 94
           N  WH  CFRC  C   LA+  FV    + LC  C  RE   K +G  K I      +  
Sbjct: 58  NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAG 111

Query: 95  EQPLIFKNDPYHPDHFNCANC 115
           +Q + +K   +H D F C+NC
Sbjct: 112 DQNVEYKGTVWHKDCFTCSNC 132



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIF 100
           WH +CF C  C++V+    F        C  CH  + A+      C KC+  I    + +
Sbjct: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITY 176

Query: 101 KNDPYHPDHFNCANC 115
           ++ P+H D F C  C
Sbjct: 177 QDQPWHADCFVCVTC 191



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%)

Query: 44  ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 101
           E F C  C++ L    +V+  G H C  C ++  A       C +C   I  D + + +K
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57

Query: 102 NDPYHPDHFNCANC 115
           N  +H   F CA C
Sbjct: 58  NRFWHDTCFRCAKC 71



 Score = 33.1 bits (74), Expect = 0.048
 Identities = 22/97 (22%), Positives = 35/97 (36%), Gaps = 10/97 (10%)

Query: 24  KLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGK 83
           K  + I    I   +  WH +CF C  C + LA   F     ++ C  C+    A+    
Sbjct: 164 KCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK--- 220

Query: 84  YICQKCHAII-----DEQPLIFKNDPYHPDHFNCANC 115
             C  C   I         + ++   +H   F+C  C
Sbjct: 221 --CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKC 255



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 14/40 (35%), Positives = 18/40 (45%)

Query: 33  VIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           V+     SWH  CF C  C   LA+  FV +  +  C  C
Sbjct: 237 VVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276


>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
          Length = 309

 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 9/81 (11%)

Query: 38  NNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIID 94
           N  WH  CFRC  C   LA+  FV    + LC  C  RE   K +G  K I      +  
Sbjct: 87  NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAG 140

Query: 95  EQPLIFKNDPYHPDHFNCANC 115
           +Q + +K   +H D F C+NC
Sbjct: 141 DQNVEYKGTVWHKDCFTCSNC 161



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIF 100
           WH +CF C  C++V+    F        C  CH  + A+      C KC+  I    + +
Sbjct: 151 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITY 205

Query: 101 KNDPYHPDHFNCANC 115
           ++ P+H D F C  C
Sbjct: 206 QDQPWHADCFVCVTC 220



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%)

Query: 44  ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 101
           E F C  C++ L    +V+  G H C  C ++  A       C +C   I  D + + +K
Sbjct: 32  EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 86

Query: 102 NDPYHPDHFNCANC 115
           N  +H   F CA C
Sbjct: 87  NRFWHDTCFRCAKC 100



 Score = 33.1 bits (74), Expect = 0.048
 Identities = 22/97 (22%), Positives = 35/97 (36%), Gaps = 10/97 (10%)

Query: 24  KLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGK 83
           K  + I    I   +  WH +CF C  C + LA   F     ++ C  C+    A+    
Sbjct: 193 KCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK--- 249

Query: 84  YICQKCHAII-----DEQPLIFKNDPYHPDHFNCANC 115
             C  C   I         + ++   +H   F+C  C
Sbjct: 250 --CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKC 284



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 14/40 (35%), Positives = 18/40 (45%)

Query: 33  VIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           V+     SWH  CF C  C   LA+  FV +  +  C  C
Sbjct: 266 VVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 305


>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
          Length = 296

 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 9/81 (11%)

Query: 38  NNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIID 94
           N  WH  CFRC  C   LA+  FV    + LC  C  RE   K +G  K I      +  
Sbjct: 74  NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAG 127

Query: 95  EQPLIFKNDPYHPDHFNCANC 115
           +Q + +K   +H D F C+NC
Sbjct: 128 DQNVEYKGTVWHKDCFTCSNC 148



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIF 100
           WH +CF C  C++V+    F        C  CH  + A+      C KC+  I    + +
Sbjct: 138 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITY 192

Query: 101 KNDPYHPDHFNCANC 115
           ++ P+H D F C  C
Sbjct: 193 QDQPWHADCFVCVTC 207



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%)

Query: 44  ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 101
           E F C  C++ L    +V+  G H C  C ++  A       C +C   I  D + + +K
Sbjct: 19  EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 73

Query: 102 NDPYHPDHFNCANC 115
           N  +H   F CA C
Sbjct: 74  NRFWHDTCFRCAKC 87



 Score = 33.1 bits (74), Expect = 0.048
 Identities = 22/97 (22%), Positives = 35/97 (36%), Gaps = 10/97 (10%)

Query: 24  KLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGK 83
           K  + I    I   +  WH +CF C  C + LA   F     ++ C  C+    A+    
Sbjct: 180 KCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK--- 236

Query: 84  YICQKCHAII-----DEQPLIFKNDPYHPDHFNCANC 115
             C  C   I         + ++   +H   F+C  C
Sbjct: 237 --CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKC 271



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 14/40 (35%), Positives = 18/40 (45%)

Query: 33  VIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           V+     SWH  CF C  C   LA+  FV +  +  C  C
Sbjct: 253 VVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 292


>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 9/81 (11%)

Query: 38  NNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIID 94
           N  WH  CFRC  C   LA+  FV    + LC  C  RE   K +G  K I      +  
Sbjct: 58  NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAG 111

Query: 95  EQPLIFKNDPYHPDHFNCANC 115
           +Q + +K   +H D F C+NC
Sbjct: 112 DQNVEYKGTVWHKDCFTCSNC 132



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIF 100
           WH +CF C  C++V+    F        C  CH  + A+      C KC+  I    + +
Sbjct: 122 WHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITY 176

Query: 101 KNDPYHPDHFNCANC 115
           ++ P+H D F C  C
Sbjct: 177 QDQPWHADCFVCVTC 191



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%)

Query: 44  ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 101
           E F C  C++ L    +V+  G H C  C ++  A       C +C   I  D + + +K
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57

Query: 102 NDPYHPDHFNCANC 115
           N  +H   F CA C
Sbjct: 58  NRFWHDTCFRCAKC 71



 Score = 33.1 bits (74), Expect = 0.048
 Identities = 22/97 (22%), Positives = 35/97 (36%), Gaps = 10/97 (10%)

Query: 24  KLGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGK 83
           K  + I    I   +  WH +CF C  C + LA   F     ++ C  C+    A+    
Sbjct: 164 KCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK--- 220

Query: 84  YICQKCHAII-----DEQPLIFKNDPYHPDHFNCANC 115
             C  C   I         + ++   +H   F+C  C
Sbjct: 221 --CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKC 255



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 14/40 (35%), Positives = 18/40 (45%)

Query: 33  VIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           V+     SWH  CF C  C   LA+  FV +  +  C  C
Sbjct: 237 VVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 91
           R ++    +WH  CF C  C++ L    FV + G H C PC+  + A       C +C  
Sbjct: 113 RKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPR-----CARCSK 167

Query: 92  IIDEQPLIFKNDPYHPDHFNCANC 115
            + +  + +++ P+H +   C  C
Sbjct: 168 TLTQGGVTYRDQPWHRECLVCTGC 191



 Score = 36.2 bits (82), Expect = 0.006
 Identities = 14/42 (33%), Positives = 20/42 (47%)

Query: 31  GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           G+ +   +  WH  CF C  C   L   GFV +  + LC+ C
Sbjct: 234 GKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275



 Score = 35.4 bits (80), Expect = 0.010
 Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 7/74 (9%)

Query: 44  ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 101
           E F C  C E L    +++      C PC++   A       C +C  +I  D + L ++
Sbjct: 3   ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFAN-----TCAECQQLIGHDSRELFYE 57

Query: 102 NDPYHPDHFNCANC 115
           +  +H   F C  C
Sbjct: 58  DRHFHEGCFRCCRC 71



 Score = 33.9 bits (76), Expect = 0.028
 Identities = 21/77 (27%), Positives = 29/77 (37%), Gaps = 7/77 (9%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPL 98
           +H  CFRC  CQ  LAD  F       LC  C+    +       C  C   +    + L
Sbjct: 61  FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQ-----CSACGETVMPGSRKL 115

Query: 99  IFKNDPYHPDHFNCANC 115
            +    +H   F C+ C
Sbjct: 116 EYGGQTWHEHCFLCSGC 132



 Score = 33.5 bits (75), Expect = 0.037
 Identities = 22/84 (26%), Positives = 33/84 (39%), Gaps = 19/84 (22%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLI- 99
           WH EC  C  CQ  LA   F        C  C         G+    KC +   ++P++ 
Sbjct: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVAC--------FGELFAPKCSSC--KRPIVG 230

Query: 100 --------FKNDPYHPDHFNCANC 115
                   F++  +H + F+CA C
Sbjct: 231 LGGGKYVSFEDRHWHHNCFSCARC 254


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 7/89 (7%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH-NREKARGLGKYICQ 87
           I G+V+ A+  +WHPE F C  C   L    F +  G   C  C+  R   R      C 
Sbjct: 235 IAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR------CG 288

Query: 88  KCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
            C+  I  + +      +HP+HF C +CG
Sbjct: 289 FCNQPIRHKMVTALGTHWHPEHFCCVSCG 317



 Score = 48.9 bits (115), Expect = 9e-07
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I+   I A++  WHP+CF C  C    +   F ++ GR LC   ++    RG    +C  
Sbjct: 353 ILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCE--NHFHARRG---SLCAT 407

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C   +  + +      +HPDHF C  C
Sbjct: 408 CGLPVTGRCVSALGRRFHPDHFTCTFC 434



 Score = 46.6 bits (109), Expect = 4e-06
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 5/84 (5%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 91
           +++ A+   WHPE F C  C E   D GF +  GR  C     R     L    CQ C  
Sbjct: 297 KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RRDFLQLFAPRCQGCQG 351

Query: 92  IIDEQPLIFKNDPYHPDHFNCANC 115
            I +  +   +  +HPD F C  C
Sbjct: 352 PILDNYISALSALWHPDCFVCREC 375



 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 15/44 (34%), Positives = 23/44 (52%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           + GR + A+   +HP+ F C  C   L    F + AG+  C+PC
Sbjct: 412 VTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 455



 Score = 28.1 bits (61), Expect = 1.6
 Identities = 11/33 (33%), Positives = 16/33 (48%)

Query: 83  KYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 115
           K +C  C+  I  Q +      +HP+HF C  C
Sbjct: 225 KGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGC 257


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 7/89 (7%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH-NREKARGLGKYICQ 87
           I G+V+ A+  +WHPE F C  C   L    F +  G   C  C+  R   R      C 
Sbjct: 218 IAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR------CG 271

Query: 88  KCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
            C+  I  + +      +HP+HF C +CG
Sbjct: 272 FCNQPIRHKMVTALGTHWHPEHFCCVSCG 300



 Score = 48.9 bits (115), Expect = 9e-07
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I+   I A++  WHP+CF C  C    +   F ++ GR LC   ++    RG    +C  
Sbjct: 336 ILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCE--NHFHARRG---SLCAT 390

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C   +  + +      +HPDHF C  C
Sbjct: 391 CGLPVTGRCVSALGRRFHPDHFTCTFC 417



 Score = 46.6 bits (109), Expect = 4e-06
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 5/84 (5%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 91
           +++ A+   WHPE F C  C E   D GF +  GR  C     R     L    CQ C  
Sbjct: 280 KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RRDFLQLFAPRCQGCQG 334

Query: 92  IIDEQPLIFKNDPYHPDHFNCANC 115
            I +  +   +  +HPD F C  C
Sbjct: 335 PILDNYISALSALWHPDCFVCREC 358



 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 15/44 (34%), Positives = 23/44 (52%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           + GR + A+   +HP+ F C  C   L    F + AG+  C+PC
Sbjct: 395 VTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438



 Score = 28.1 bits (61), Expect = 1.6
 Identities = 11/33 (33%), Positives = 16/33 (48%)

Query: 83  KYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 115
           K +C  C+  I  Q +      +HP+HF C  C
Sbjct: 208 KGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGC 240


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score = 52.4 bits (124), Expect = 8e-08
 Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I G  + AM  SWHPE F C  C+  LAD+ FV+      C  C+ +  A      +C K
Sbjct: 448 IRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP-----LCAK 502

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C+  I  + +      +H   F CA C
Sbjct: 503 CNTKIMGEVMHALRQTWHTTCFVCAAC 529



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 24/98 (24%), Positives = 35/98 (35%), Gaps = 23/98 (23%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR---------PCHNREKAR 79
           I+G V+ A+  +WH  CF C  C++   +  F    G   C           CH  +   
Sbjct: 507 IMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPV 566

Query: 80  GLGK--------------YICQKCHAIIDEQPLIFKND 103
             G               +IC  CH  ++ QP   K D
Sbjct: 567 EAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKD 604



 Score = 32.7 bits (73), Expect = 0.063
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 70
           + I+A+ ++WH  CF C +C   L    F     R LC+
Sbjct: 571 KFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609



 Score = 27.7 bits (60), Expect = 2.0
 Identities = 10/31 (32%), Positives = 16/31 (51%)

Query: 85  ICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 115
           +C  C+ +I    L+     +HP+ F CA C
Sbjct: 440 LCGHCNNVIRGPFLVAMGRSWHPEEFTCAYC 470


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 52.4 bits (124), Expect = 8e-08
 Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
           I G  + AM  SWHPE F C  C+  LAD+ FV+      C  C+ +  A      +C K
Sbjct: 558 IRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP-----LCAK 612

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
           C+  I  + +      +H   F CA C
Sbjct: 613 CNTKIMGEVMHALRQTWHTTCFVCAAC 639



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 24/98 (24%), Positives = 35/98 (35%), Gaps = 23/98 (23%)

Query: 29  IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR---------PCHNREKAR 79
           I+G V+ A+  +WH  CF C  C++   +  F    G   C           CH  +   
Sbjct: 617 IMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPV 676

Query: 80  GLGK--------------YICQKCHAIIDEQPLIFKND 103
             G               +IC  CH  ++ QP   K D
Sbjct: 677 EAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKD 714



 Score = 32.7 bits (73), Expect = 0.063
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 70
           + I+A+ ++WH  CF C +C   L    F     R LC+
Sbjct: 681 KFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719



 Score = 27.7 bits (60), Expect = 2.0
 Identities = 10/31 (32%), Positives = 16/31 (51%)

Query: 85  ICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 115
           +C  C+ +I    L+     +HP+ F CA C
Sbjct: 550 LCGHCNNVIRGPFLVAMGRSWHPEEFTCAYC 580


>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 91
           R ++   +SWH  CF C  CQ+ +    F+    ++ C PC+ ++ A       C +C  
Sbjct: 113 RKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQ-----CVQCKK 167

Query: 92  IIDEQPLIFKNDPYHPDHFNCANC 115
            I    + ++  P+H + F C  C
Sbjct: 168 PITTGGVTYREQPWHKECFVCTAC 191



 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 7/77 (9%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPL 98
           WH  CF C  C+  L D  F     + LC  C++ E +       CQ+C   I    + +
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKM 115

Query: 99  IFKNDPYHPDHFNCANC 115
            +K   +H   F C  C
Sbjct: 116 EYKGSSWHETCFICHRC 132



 Score = 34.7 bits (78), Expect = 0.017
 Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 25/87 (28%)

Query: 41  WHPECFRCDLCQEVLA--------DIGFVKNAGRHL----CRPCHNREKARGLGKYICQK 88
           WH ECF C  C++ L+        D  +  N    L    C  C N     G  KYI   
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS-- 238

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
                      F+   +H D FNC  C
Sbjct: 239 -----------FEERQWHNDCFNCKKC 254



 Score = 31.2 bits (69), Expect = 0.18
 Identities = 13/41 (31%), Positives = 16/41 (39%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           + I      WH +CF C  C   L   GF+      LC  C
Sbjct: 235 KYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275


>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 91
           R ++   +SWH  CF C  CQ+ +    F+    ++ C PC+ ++ A       C +C  
Sbjct: 113 RKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQ-----CVQCKK 167

Query: 92  IIDEQPLIFKNDPYHPDHFNCANC 115
            I    + ++  P+H + F C  C
Sbjct: 168 PITTGGVTYREQPWHKECFVCTAC 191



 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 7/77 (9%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPL 98
           WH  CF C  C+  L D  F     + LC  C++ E +       CQ+C   I    + +
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKM 115

Query: 99  IFKNDPYHPDHFNCANC 115
            +K   +H   F C  C
Sbjct: 116 EYKGSSWHETCFICHRC 132



 Score = 34.7 bits (78), Expect = 0.017
 Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 25/87 (28%)

Query: 41  WHPECFRCDLCQEVLA--------DIGFVKNAGRHL----CRPCHNREKARGLGKYICQK 88
           WH ECF C  C++ L+        D  +  N    L    C  C N     G  KYI   
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS-- 238

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
                      F+   +H D FNC  C
Sbjct: 239 -----------FEERQWHNDCFNCKKC 254



 Score = 31.2 bits (69), Expect = 0.18
 Identities = 13/41 (31%), Positives = 16/41 (39%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           + I      WH +CF C  C   L   GF+      LC  C
Sbjct: 235 KYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275


>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 91
           R ++   +SWH  CF C  CQ+ +    F+    ++ C PC+ ++ A       C +C  
Sbjct: 113 RKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQ-----CVQCKK 167

Query: 92  IIDEQPLIFKNDPYHPDHFNCANC 115
            I    + ++  P+H + F C  C
Sbjct: 168 PITTGGVTYREQPWHKECFVCTAC 191



 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 7/77 (9%)

Query: 41  WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPL 98
           WH  CF C  C+  L D  F     + LC  C++ E +       CQ+C   I    + +
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKM 115

Query: 99  IFKNDPYHPDHFNCANC 115
            +K   +H   F C  C
Sbjct: 116 EYKGSSWHETCFICHRC 132



 Score = 34.7 bits (78), Expect = 0.017
 Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 25/87 (28%)

Query: 41  WHPECFRCDLCQEVLA--------DIGFVKNAGRHL----CRPCHNREKARGLGKYICQK 88
           WH ECF C  C++ L+        D  +  N    L    C  C N     G  KYI   
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS-- 238

Query: 89  CHAIIDEQPLIFKNDPYHPDHFNCANC 115
                      F+   +H D FNC  C
Sbjct: 239 -----------FEERQWHNDCFNCKKC 254



 Score = 31.2 bits (69), Expect = 0.18
 Identities = 13/41 (31%), Positives = 16/41 (39%)

Query: 32  RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 72
           + I      WH +CF C  C   L   GF+      LC  C
Sbjct: 235 KYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.147    0.529 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,268,309
Number of Sequences: 37866
Number of extensions: 230893
Number of successful extensions: 1152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 684
Number of HSP's gapped (non-prelim): 383
length of query: 116
length of database: 18,247,518
effective HSP length: 86
effective length of query: 30
effective length of database: 14,991,042
effective search space: 449731260
effective search space used: 449731260
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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